
Main files: 

test_TMTL_r3.m —— main test file for model training and testing
TMTL.m —— algorithm file for first time training (without biomarker latent factor knowledge base)
TMTL_2.m —— algorithm file for subsequent time training (with biomarker latent factor knowledge base)

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P.S. Because the datasets' size exceeds the available max limit set by OpenReview (The OpenReview limit is 100M, but our dataset is 15.1GB), therefore uploaded dataset is a subset of our data, so the test results can be different during tests. It is also inconvenient to store datasets to cloud storage based on double-blind rules, we are happy to provide the full dataset when needed.

The training time of cross-validation is longer than the specific model parameter test, and the specific time depends on the number of model parameter set for cross-validation. 

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For MMSE prediction: 

Before testing, please put the dataset file ADNI_MRI_BL_to_M06_to_M12_to_M24_(MMSE) into the TMTCL/data/ folder. 

In test_TMTL_r3.m
Please uncomment line 7, lines 19-35, line 238, lines 250-266, line 474, lines 485-501.
comment line 8, lines 40-56, line 239, lines 272-288, line 475, lines 507-523. 

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For ADAS-Cog prediction: 

Before testing, please put the dataset file ADNI_MRI_BL_to_M06_to_M12_to_M24_(ADAS) into the TMTCL/data/ folder. 

In test_TMTL_r3.m
Please uncomment line 8, lines 40-56, line 239, lines 272-288, line 475, lines 507-523. 
comment line 7, lines 19-35, line 238, lines 250-266, line 474, lines 485-501.

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For specific model parameter test: 

In test_TMTL_r3.m
Please uncomment lines 159-167, lines 390-399, lines 625-634. 
comment lines 153-154, lines 384-385, lines 619-620. 

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For model training and cross-validation: 

In test_TMTL_r3.m
Please uncomment lines 153-154, lines 384-385, lines 619-620. 
comment lines 159-167, lines 390-399, lines 625-634. 

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