{
  "ptid_time": "021_S_1109_2007-07-10",
  "img_path": "/data/qiuhui/data/adni/images/021_S_1109/2007-07-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 25,220 mm³, 10.1% below the reference mean. With a Z-score of -0.23 (40.8th percentile), this represents normal volume ; hippocampal volume measures 4,435 mm³, 37.7% below the reference mean. With a Z-score of -3.45 (0.0th percentile), this represents profound atrophy; whole brain volume measures 814,557 mm³, 16.4% below the reference mean. With a Z-score of -2.07 (1.9th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,857 mm³, 49.4% below the reference mean. With a Z-score of -3.03 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,032 mm³, 35.2% below the reference mean. With a Z-score of -3.20 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 13,564 mm³, 29.2% below the reference mean. With a Z-score of -2.54 (0.6th percentile), this represents significant atrophy. ",
  "text_data": "Age is 78.3 years. Gender is Female. Education: 17 years. MMSE: 20.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The imaging data shows profound atrophy in the hippocampus, entorhinal cortex, and fusiform gyrus, along with significant atrophy in the whole brain and middle temporal gyrus—key regions affected in Alzheimer's disease. The MMSE score of 20.0 indicates cognitive impairment, and the presence of one APOE4 allele further supports an Alzheimer's pathology.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: High",
  "timestamp": "2025-07-26T01:36:43.171976"
}