{
  "ptid_time": "128_S_0740_2006-07-31",
  "img_path": "/data/qiuhui/data/adni/images/128_S_0740/2006-07-31/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,550 mm³, 15.7% above the reference mean. With a Z-score of 0.38 (64.6th percentile), this represents normal volume ; hippocampal volume measures 5,683 mm³, 24.8% below the reference mean. With a Z-score of -2.42 (0.8th percentile), this represents significant atrophy; whole brain volume measures 975,848 mm³, 9.6% below the reference mean. With a Z-score of -1.25 (10.7th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,535 mm³, 38.2% below the reference mean. With a Z-score of -2.59 (0.5th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,025 mm³, 25.6% below the reference mean. With a Z-score of -2.18 (1.5th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,724 mm³, 31.0% below the reference mean. With a Z-score of -2.79 (0.3th percentile), this represents significant atrophy. ",
  "text_data": "Age is 72.2 years. Gender is Male. Education: 15 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 22.0. Logical Memory: 1.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), along with mild whole-brain atrophy. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk. These findings are consistent with neurodegenerative disease.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T13:49:15.753036"
}