{
  "ptid_time": "011_S_0002_2005-08-26",
  "img_path": "/data/qiuhui/data/adni/images/011_S_0002/2005-08-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 118,233 mm³, 207.0% above the reference mean. With a Z-score of 4.96 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 8,336 mm³, 10.3% above the reference mean. With a Z-score of 1.00 (84.2th percentile), this represents mild enlargement; whole brain volume measures 1,229,740 mm³, 13.9% above the reference mean. With a Z-score of 1.81 (96.5th percentile), this represents moderate enlargement; entorhinal cortex volume measures 4,177 mm³, 1.9% above the reference mean. With a Z-score of 0.13 (55.0th percentile), this represents normal volume ; fusiform gyrus volume measures 16,559 mm³, 12.1% below the reference mean. With a Z-score of -1.03 (15.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 27,936 mm³, 30.9% above the reference mean. With a Z-score of 2.78 (99.7th percentile), this represents significant enlargement. ",
  "text_data": "Age is 74.3 years. Gender is Male. Education: 16 years. Handedness: Left. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Endocrine-Metabolic. MMSE: 28.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 4.96), which is strongly associated with neurodegeneration, alongside mild fusiform gyrus atrophy (Z-score -1.03). However, hippocampal volume is mildly enlarged (Z-score 1.00), and MMSE is normal (28/30), suggesting preserved cognitive function. The absence of APOE4 and normal entorhinal cortex volume reduce Alzheimer's likelihood.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (due to conflicting findings—ventricular enlargement suggests possible early neurodegeneration, but other markers and MMSE support normal cognition).",
  "timestamp": "2025-07-25T22:36:16.052168"
}