{
  "ptid_time": "094_S_4560_2012-03-16",
  "img_path": "/data/qiuhui/data/adni/images/094_S_4560/2012-03-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 25,156 mm³, 10.4% below the reference mean. With a Z-score of -0.24 (40.6th percentile), this represents normal volume ; hippocampal volume measures 6,679 mm³, 6.1% below the reference mean. With a Z-score of -0.56 (28.7th percentile), this represents normal volume ; whole brain volume measures 936,000 mm³, 4.0% below the reference mean. With a Z-score of -0.50 (30.9th percentile), this represents normal volume ; entorhinal cortex volume measures 3,670 mm³, 0.1% below the reference mean. With a Z-score of -0.00 (49.8th percentile), this represents normal volume ; fusiform gyrus volume measures 20,199 mm³, 18.7% above the reference mean. With a Z-score of 1.70 (95.6th percentile), this represents moderate enlargement; middle temporal gyrus volume measures 17,482 mm³, 8.8% below the reference mean. With a Z-score of -0.76 (22.2th percentile), this represents normal volume . ",
  "text_data": "Age is 70.3 years. Gender is Female. Education: 20 years. Handedness: Left. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Allergies or Drug Sensitivities. MMSE: 28.0. MoCA: 24.0. Logical Memory: 15.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.97 SUVR (normal ); Total tau: 211.80 pg/mL (normal ); Phosphorylated tau: 18.98 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "Reasoning: The brain volume measurements are largely within normal ranges, with only mild deviations (e.g., fusiform gyrus enlargement, middle temporal gyrus slightly below mean). Cognitive scores (MMSE 28, MoCA 24) suggest mild cognitive concern (MoCA <26 is typical for MCI), but biomarkers (normal tau, amyloid) and APOE4-negative status do not strongly support Alzheimer's pathology.  \nDiagnosis: **MCI** (mild cognitive impairment, likely non-amnestic or non-Alzheimer's subtype)  \nConfidence: **Medium** (cognitive scores indicate impairment, but biomarker profile is atypical for AD; other etiologies like vascular or non-neurodegenerative causes should be considered).",
  "timestamp": "2025-07-26T10:31:54.671395"
}