{
  "ptid_time": "127_S_1419_2009-08-19",
  "img_path": "/data/qiuhui/data/adni/images/127_S_1419/2009-08-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 47,712 mm³, 23.9% above the reference mean. With a Z-score of 0.57 (71.6th percentile), this represents normal volume ; hippocampal volume measures 6,954 mm³, 8.0% below the reference mean. With a Z-score of -0.78 (21.7th percentile), this represents normal volume ; whole brain volume measures 1,169,610 mm³, 8.4% above the reference mean. With a Z-score of 1.08 (86.1th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,927 mm³, 4.2% below the reference mean. With a Z-score of -0.29 (38.7th percentile), this represents normal volume ; fusiform gyrus volume measures 20,676 mm³, 9.8% above the reference mean. With a Z-score of 0.83 (79.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,968 mm³, 7.6% above the reference mean. With a Z-score of 0.69 (75.4th percentile), this represents normal volume . ",
  "text_data": "Age is 79.9 years. Gender is Male. Education: 17 years. MMSE: 29.0. Logical Memory: 5.0. APOEε4 alleles: 1.0. Biomarker levels: Pittsburgh compound B: 2.38 SUVR (significant elevated); Amyloid beta: 335.80 pg/mL (moderate reduced); Total tau: 243.30 pg/mL (normal ); Phosphorylated tau: 23.21 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume is slightly reduced (8.0% below mean, Z-score -0.78), but still within the normal range. Aβ is moderately reduced, suggesting amyloid pathology, but cognitive function (MMSE 29) remains intact.  \n**Diagnosis:** **MCI** (due to amyloid burden and subtle hippocampal changes, but no significant cognitive decline yet).  \n**Confidence:** **Medium** (clinical correlation needed; cognitive testing is borderline normal).",
  "timestamp": "2025-07-26T13:08:44.493347"
}