{
  "ptid_time": "127_S_1419_2007-07-23",
  "img_path": "/data/qiuhui/data/adni/images/127_S_1419/2007-07-23/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 39,896 mm³, 3.6% above the reference mean. With a Z-score of 0.09 (53.4th percentile), this represents normal volume ; hippocampal volume measures 7,498 mm³, 0.8% below the reference mean. With a Z-score of -0.08 (46.9th percentile), this represents normal volume ; whole brain volume measures 1,181,030 mm³, 9.4% above the reference mean. With a Z-score of 1.22 (88.9th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,979 mm³, 3.0% below the reference mean. With a Z-score of -0.20 (42.0th percentile), this represents normal volume ; fusiform gyrus volume measures 21,342 mm³, 13.3% above the reference mean. With a Z-score of 1.13 (87.1th percentile), this represents mild enlargement; middle temporal gyrus volume measures 23,938 mm³, 12.2% above the reference mean. With a Z-score of 1.09 (86.3th percentile), this represents mild enlargement. ",
  "text_data": "Age is 77.9 years. Gender is Male. Education: 17 years. Handedness: Right. Race: White. Medical history: Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Smoking; Malignancy; Major Surgical Procedures. MMSE: 28.0. Logical Memory: 7.0. APOEε4 alleles: 1.0. Biomarker levels: Pittsburgh compound B: 1.83 SUVR (normal ); Amyloid beta: 390.50 pg/mL (moderate reduced); Total tau: 234.90 pg/mL (normal ); Phosphorylated tau: 22.48 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges or mildly enlarged, with no significant atrophy in key regions like the hippocampus or entorhinal cortex. The MMSE score of 28 is within the normal range, and while Aβ is moderately reduced (suggesting amyloid pathology), tau markers (T-tau, P-tau) are normal, indicating no active neurodegeneration.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (due to the presence of amyloid pathology but lack of clinical or structural correlates of impairment)",
  "timestamp": "2025-07-26T13:08:11.423637"
}