{
  "ptid_time": "126_S_6724_2019-05-02",
  "img_path": "/data/qiuhui/data/adni/images/126_S_6724/2019-05-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,663 mm³, 86.1% above the reference mean. With a Z-score of 2.06 (98.0th percentile), this represents significant enlargement; hippocampal volume measures 6,849 mm³, 9.4% below the reference mean. With a Z-score of -0.92 (18.0th percentile), this represents normal volume ; whole brain volume measures 1,032,390 mm³, 4.4% below the reference mean. With a Z-score of -0.57 (28.6th percentile), this represents normal volume ; entorhinal cortex volume measures 4,255 mm³, 3.8% above the reference mean. With a Z-score of 0.26 (60.1th percentile), this represents normal volume ; fusiform gyrus volume measures 18,799 mm³, 0.2% below the reference mean. With a Z-score of -0.02 (49.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,759 mm³, 7.4% below the reference mean. With a Z-score of -0.67 (25.3th percentile), this represents normal volume . ",
  "text_data": "Age is 75.4 years. Gender is Male. Education: 17 years. Handedness: Right. Race: White. MMSE: 26.0. MoCA: 21.0. Logical Memory: 8.0. APOEε4 alleles: 1.0. Biomarker levels: Flobetaben (FBB): 1.35 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (98th percentile), which is often associated with brain atrophy, but hippocampal volume is only mildly reduced (18th percentile) and within normal range. Cognitive scores (MMSE 26, MoCA 21) suggest mild cognitive impairment (MCI), particularly given the MoCA score below the typical cutoff of 26. The presence of one APOE4 allele increases Alzheimer's risk but does not confirm dementia.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Cognitive scores align with MCI, but structural changes are not severe enough for a dementia diagnosis at this stage.)",
  "timestamp": "2025-07-26T12:54:24.113569"
}