{
  "ptid_time": "006_S_4713_2012-05-14",
  "img_path": "/data/qiuhui/data/adni/images/006_S_4713/2012-05-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 25,029 mm³, 35.0% below the reference mean. With a Z-score of -0.84 (20.1th percentile), this represents normal volume ; whole brain volume measures 1,179,040 mm³, 9.2% above the reference mean. With a Z-score of 1.20 (88.5th percentile), this represents mild enlargement; entorhinal cortex volume measures 5,572 mm³, 35.9% above the reference mean. With a Z-score of 2.43 (99.3th percentile), this represents significant enlargement; fusiform gyrus volume measures 20,244 mm³, 7.5% above the reference mean. With a Z-score of 0.64 (73.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 23,203 mm³, 8.7% above the reference mean. With a Z-score of 0.79 (78.4th percentile), this represents normal volume . ",
  "text_data": "Age is 70.5 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Gastrointestinal; Allergies or Drug Sensitivities; Smoking; Malignancy; Major Surgical Procedures. MMSE: 30.0. MoCA: 25.0. Logical Memory: 8.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.22 SUVR (mild elevated); Amyloid beta: 954.80 pg/mL (normal ); Total tau: 303.70 pg/mL (normal ); Phosphorylated tau: 26.70 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows normal or above-average volumes in key regions (e.g., entorhinal cortex, fusiform gyrus, middle temporal gyrus), with no significant atrophy. Biomarkers (Aβ, T-tau, P-tau) are normal, though AV45 (amyloid PET) is mildly elevated. Cognitive scores (MMSE 30, MoCA 25) are within normal limits for age, with MoCA slightly lower but not indicative of impairment. APOE4 carrier status increases Alzheimer's risk but does not confirm pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mildly elevated AV45 and slightly lower MoCA, but otherwise normal biomarkers and volumes)",
  "timestamp": "2025-07-25T21:40:31.461886"
}