{
  "ptid_time": "002_S_4225_2018-11-12",
  "img_path": "/data/qiuhui/data/adni/images/002_S_4225/2018-11-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 70,794 mm³, 83.8% above the reference mean. With a Z-score of 2.01 (97.8th percentile), this represents significant enlargement; hippocampal volume measures 5,920 mm³, 21.7% below the reference mean. With a Z-score of -2.12 (1.7th percentile), this represents significant atrophy; whole brain volume measures 1,166,920 mm³, 8.1% above the reference mean. With a Z-score of 1.05 (85.4th percentile), this represents mild enlargement; entorhinal cortex volume measures 2,926 mm³, 28.6% below the reference mean. With a Z-score of -1.94 (2.6th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,621 mm³, 1.2% below the reference mean. With a Z-score of -0.10 (46.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 23,253 mm³, 9.0% above the reference mean. With a Z-score of 0.81 (79.0th percentile), this represents normal volume . ",
  "text_data": "Age is 76.9 years. Gender is Male. Education: 20 years. MMSE: 21.0. MoCA: 19.0. Logical Memory: 2.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.66 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD), alongside profound amyloid positivity (AV45). The cognitive scores (MMSE 21, MoCA 19) indicate moderate impairment, consistent with dementia. Ventricular enlargement further supports neurodegeneration.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T20:23:00.741532"
}