{
  "ptid_time": "130_S_4641_2014-05-02",
  "img_path": "/data/qiuhui/data/adni/images/130_S_4641/2014-05-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 72,077 mm³, 156.8% above the reference mean. With a Z-score of 3.59 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,043 mm³, 15.1% below the reference mean. With a Z-score of -1.38 (8.4th percentile), this represents mild atrophy; whole brain volume measures 1,042,760 mm³, 7.0% above the reference mean. With a Z-score of 0.88 (81.0th percentile), this represents normal volume ; entorhinal cortex volume measures 3,353 mm³, 8.7% below the reference mean. With a Z-score of -0.53 (29.6th percentile), this represents normal volume ; fusiform gyrus volume measures 18,309 mm³, 7.6% above the reference mean. With a Z-score of 0.69 (75.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,575 mm³, 7.3% above the reference mean. With a Z-score of 0.64 (73.8th percentile), this represents normal volume . ",
  "text_data": "Age is 75.6 years. Gender is Female. Education: 20 years. MMSE: 28.0. MoCA: 24.0. Logical Memory: 1.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.38 SUVR (significant elevated); Amyloid beta: 461.20 pg/mL (mild reduced); Total tau: 247.10 pg/mL (normal ); Phosphorylated tau: 23.02 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (indicating significant brain atrophy) and mild hippocampal atrophy, both of which are associated with Alzheimer's disease. The MMSE (28) is normal, but the MoCA (24) suggests mild cognitive impairment, supported by mildly reduced Aβ and significantly elevated AV45 (amyloid PET), consistent with early Alzheimer's pathology.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**, likely due to Alzheimer’s disease.  \n\n**Confidence:** **Medium** (clinical scores are borderline, but imaging and biomarkers strongly suggest early Alzheimer’s pathology).",
  "timestamp": "2025-07-26T14:50:47.051951"
}