{
  "ptid_time": "037_S_1225_2008-02-11",
  "img_path": "/data/qiuhui/data/adni/images/037_S_1225/2008-02-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 36,660 mm³, 4.8% below the reference mean. With a Z-score of -0.12 (45.4th percentile), this represents normal volume ; hippocampal volume measures 3,948 mm³, 47.8% below the reference mean. With a Z-score of -4.66 (0.0th percentile), this represents profound atrophy; whole brain volume measures 918,974 mm³, 14.9% below the reference mean. With a Z-score of -1.93 (2.7th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,553 mm³, 37.7% below the reference mean. With a Z-score of -2.56 (0.5th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,248 mm³, 24.4% below the reference mean. With a Z-score of -2.08 (1.9th percentile), this represents significant atrophy; middle temporal gyrus volume measures 19,515 mm³, 8.5% below the reference mean. With a Z-score of -0.77 (22.1th percentile), this represents normal volume . ",
  "text_data": "Age is 77.4 years. Gender is Male. Education: 20 years. MMSE: 28.0. Logical Memory: 2.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The hippocampal volume shows profound atrophy (Z-score -4.66, 0.0th percentile), and there is significant atrophy in the entorhinal cortex and fusiform gyrus, which are key regions affected in Alzheimer's disease. However, the MMSE score of 28 is within the normal range, and ventricular volume is normal, suggesting preserved cognitive function despite structural changes.  \nDiagnosis: MCI (Mild Cognitive Impairment)  \nConfidence: Medium  \n\n(Note: The discrepancy between severe structural atrophy and normal MMSE could indicate preclinical or very early-stage cognitive decline. APOE4-negative status reduces Alzheimer's risk but doesn't rule it out. Follow-up clinical correlation is advised.)",
  "timestamp": "2025-07-26T06:37:00.039042"
}