{
  "ptid_time": "062_S_0535_2006-12-14",
  "img_path": "/data/qiuhui/data/adni/images/062_S_0535/2006-12-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 56,798 mm³, 47.5% above the reference mean. With a Z-score of 1.14 (87.2th percentile), this represents mild enlargement; hippocampal volume measures 4,705 mm³, 37.8% below the reference mean. With a Z-score of -3.68 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,025,360 mm³, 5.0% below the reference mean. With a Z-score of -0.65 (25.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,912 mm³, 29.0% below the reference mean. With a Z-score of -1.97 (2.5th percentile), this represents moderate atrophy; fusiform gyrus volume measures 16,134 mm³, 14.4% below the reference mean. With a Z-score of -1.22 (11.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,762 mm³, 21.4% below the reference mean. With a Z-score of -1.93 (2.7th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 77.3 years. Gender is Male. Education: 15 years. MMSE: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound hippocampal atrophy (Z-score -3.68) and moderate atrophy in the entorhinal cortex and middle temporal gyrus, which are key regions affected in Alzheimer’s disease. The MMSE score of 23 suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer’s risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T08:16:15.379036"
}