{
  "ptid_time": "116_S_4175_2015-09-03",
  "img_path": "/data/qiuhui/data/adni/images/116_S_4175/2015-09-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,037 mm³, 19.4% below the reference mean. With a Z-score of -0.47 (32.1th percentile), this represents normal volume ; hippocampal volume measures 7,901 mm³, 4.5% above the reference mean. With a Z-score of 0.44 (67.0th percentile), this represents normal volume ; whole brain volume measures 1,019,260 mm³, 5.6% below the reference mean. With a Z-score of -0.72 (23.5th percentile), this represents normal volume ; entorhinal cortex volume measures 4,262 mm³, 3.9% above the reference mean. With a Z-score of 0.27 (60.5th percentile), this represents normal volume ; fusiform gyrus volume measures 18,575 mm³, 1.4% below the reference mean. With a Z-score of -0.12 (45.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,770 mm³, 7.4% below the reference mean. With a Z-score of -0.66 (25.4th percentile), this represents normal volume . ",
  "text_data": "Age is 79.5 years. Gender is Male. Education: 20 years. MMSE: 25.0. MoCA: 22.0. Logical Memory: 6.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.34 SUVR (significant elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements (hippocampus, entorhinal cortex, fusiform gyrus, etc.) are within normal ranges, with no significant atrophy. The MMSE (25) and MoCA (22) scores suggest mild cognitive impairment, but not dementia. The presence of one APOE4 allele and elevated AV45 (amyloid PET) indicates amyloid pathology, increasing Alzheimer's risk.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment)**  \n**Confidence:** **Medium** (Cognitive scores suggest MCI, but structural imaging is normal; amyloid positivity supports early Alzheimer's-related MCI.)",
  "timestamp": "2025-07-26T12:08:50.147997"
}