{
  "ptid_time": "941_S_6044_2017-07-17",
  "img_path": "/data/qiuhui/data/adni/images/941_S_6044/2017-07-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 26,936 mm³, 4.0% below the reference mean. With a Z-score of -0.09 (46.3th percentile), this represents normal volume ; hippocampal volume measures 8,864 mm³, 24.6% above the reference mean. With a Z-score of 2.26 (98.8th percentile), this represents significant enlargement; whole brain volume measures 1,157,370 mm³, 18.7% above the reference mean. With a Z-score of 2.36 (99.1th percentile), this represents significant enlargement; entorhinal cortex volume measures 4,863 mm³, 32.4% above the reference mean. With a Z-score of 1.99 (97.7th percentile), this represents moderate enlargement; fusiform gyrus volume measures 21,017 mm³, 23.5% above the reference mean. With a Z-score of 2.14 (98.4th percentile), this represents significant enlargement; middle temporal gyrus volume measures 20,242 mm³, 5.6% above the reference mean. With a Z-score of 0.49 (68.6th percentile), this represents normal volume . ",
  "text_data": "Age is 75.0 years. Gender is Female. Education: 18 years. Handedness: Right. Race: White. MMSE: 30.0. MoCA: 25.0. Logical Memory: 14.0. APOEε4 alleles: 2.0. Biomarker levels: Flobetaben (FBB): 1.50 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volumes show significant enlargement in key regions (hippocampus, whole brain, entorhinal cortex, fusiform gyrus), which is atypical for Alzheimer's disease (AD) where atrophy is expected. The MMSE (30/30) is normal, while the MoCA (25/30) suggests mild cognitive inefficiency, but not impairment. APOE4 homozygosity increases AD risk, but the volumetric findings contradict typical AD progression.  \n\n**Diagnosis:** **Cognitively Normal (CN)**  \n**Confidence:** **Medium** (due to conflicting MoCA score and APOE4 status, but strong volumetric evidence against neurodegeneration)",
  "timestamp": "2025-07-26T17:44:42.318163"
}