{
  "ptid_time": "067_S_0336_2006-05-04",
  "img_path": "/data/qiuhui/data/adni/images/067_S_0336/2006-05-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 26,507 mm³, 31.2% below the reference mean. With a Z-score of -0.75 (22.8th percentile), this represents normal volume ; hippocampal volume measures 5,622 mm³, 25.6% below the reference mean. With a Z-score of -2.50 (0.6th percentile), this represents significant atrophy; whole brain volume measures 953,844 mm³, 11.6% below the reference mean. With a Z-score of -1.51 (6.6th percentile), this represents moderate atrophy; entorhinal cortex volume measures 3,346 mm³, 18.4% below the reference mean. With a Z-score of -1.25 (10.6th percentile), this represents mild atrophy; fusiform gyrus volume measures 12,810 mm³, 32.0% below the reference mean. With a Z-score of -2.73 (0.3th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,174 mm³, 38.3% below the reference mean. With a Z-score of -3.44 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 76.1 years. Gender is Male. Education: 17 years. MMSE: 24.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 854.20 pg/mL (normal ); Total tau: 416.40 pg/mL (significant elevated); Phosphorylated tau: 45.17 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The data shows significant atrophy in the hippocampus, fusiform gyrus, and profound atrophy in the middle temporal gyrus, which are key regions affected in Alzheimer's disease. Elevated T-tau and P-tau levels, along with normal Aβ, suggest a tauopathy, likely Alzheimer's pathology, despite the MMSE score of 24 indicating only mild cognitive impairment.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: High",
  "timestamp": "2025-07-26T08:29:54.574861"
}