{
  "ptid_time": "127_S_0394_2007-01-04",
  "img_path": "/data/qiuhui/data/adni/images/127_S_0394/2007-01-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 62,573 mm³, 69.3% above the reference mean. With a Z-score of 1.87 (96.9th percentile), this represents moderate enlargement; hippocampal volume measures 6,099 mm³, 6.1% below the reference mean. With a Z-score of -0.49 (31.3th percentile), this represents normal volume ; whole brain volume measures 805,283 mm³, 13.2% below the reference mean. With a Z-score of -1.59 (5.6th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,526 mm³, 27.0% below the reference mean. With a Z-score of -1.46 (7.2th percentile), this represents mild atrophy; fusiform gyrus volume measures 11,079 mm³, 31.2% below the reference mean. With a Z-score of -2.35 (0.9th percentile), this represents significant atrophy; middle temporal gyrus volume measures 12,564 mm³, 30.3% below the reference mean. With a Z-score of -2.70 (0.3th percentile), this represents significant atrophy. ",
  "text_data": "Age is 84.5 years. Gender is Female. Education: 12 years. MMSE: 19.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (fusiform gyrus, middle temporal gyrus, entorhinal cortex, and whole brain), alongside moderate ventricular enlargement, consistent with neurodegeneration. The MMSE score of 19 (indicating moderate cognitive impairment) in an 84.5-year-old female further supports a dementia diagnosis, despite the absence of APOE4.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease given the pattern of atrophy)  \n**Confidence:** High",
  "timestamp": "2025-07-26T12:59:51.475390"
}