{
  "ptid_time": "007_S_2106_2010-12-29",
  "img_path": "/data/qiuhui/data/adni/images/007_S_2106/2010-12-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 25,859 mm³, 32.9% below the reference mean. With a Z-score of -0.79 (21.6th percentile), this represents normal volume ; hippocampal volume measures 7,159 mm³, 5.3% below the reference mean. With a Z-score of -0.52 (30.3th percentile), this represents normal volume ; whole brain volume measures 1,093,050 mm³, 1.3% above the reference mean. With a Z-score of 0.16 (56.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,629 mm³, 11.5% below the reference mean. With a Z-score of -0.78 (21.8th percentile), this represents normal volume ; fusiform gyrus volume measures 18,088 mm³, 4.0% below the reference mean. With a Z-score of -0.34 (36.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,790 mm³, 6.8% above the reference mean. With a Z-score of 0.61 (72.9th percentile), this represents normal volume . ",
  "text_data": "Age is 77.5 years. Gender is Male. Education: 12 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Endocrine-Metabolic; Renal-Genitourinary; Major Surgical Procedures. MMSE: 29.0. Logical Memory: 7.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.42 SUVR (significant elevated); Amyloid beta: 361.30 pg/mL (moderate reduced); Total tau: 414.60 pg/mL (significant elevated); Phosphorylated tau: 48.31 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volume measurements are within normal ranges, with no significant atrophy in key regions like the hippocampus or entorhinal cortex. However, the biomarker profile (elevated Aβ, T-tau, P-tau, and AV45) suggests significant amyloid deposition and tau pathology, which are indicative of Alzheimer's disease despite the preserved cognitive function (MMSE 29).  \nDiagnosis: **MCI** (due to biomarker evidence of AD pathology, but no significant cognitive decline yet)  \nConfidence: **Medium** (biomarkers strongly suggest AD pathology, but cognitive performance remains intact, making MCI more likely than dementia at this stage).",
  "timestamp": "2025-07-25T21:56:31.927194"
}