{
  "ptid_time": "003_S_0908_2007-10-25",
  "img_path": "/data/qiuhui/data/adni/images/003_S_0908/2007-10-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 51,420 mm³, 130.2% above the reference mean. With a Z-score of 3.26 (99.9th percentile), this represents profound enlargement; hippocampal volume measures 7,440 mm³, 3.2% below the reference mean. With a Z-score of -0.36 (36.1th percentile), this represents normal volume ; whole brain volume measures 1,067,730 mm³, 3.7% above the reference mean. With a Z-score of 0.47 (68.0th percentile), this represents normal volume ; entorhinal cortex volume measures 4,015 mm³, 3.1% above the reference mean. With a Z-score of 0.24 (59.6th percentile), this represents normal volume ; fusiform gyrus volume measures 16,322 mm³, 10.4% below the reference mean. With a Z-score of -1.17 (12.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 20,393 mm³, 0.6% below the reference mean. With a Z-score of -0.05 (47.8th percentile), this represents normal volume . ",
  "text_data": "Age is 63.9 years. Gender is Female. Education: 16 years. MMSE: 28.0. Logical Memory: 13.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 863.40 pg/mL (normal ); Total tau: 162.60 pg/mL (normal ); Phosphorylated tau: 15.93 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.26), which is a strong indicator of neurodegeneration, but hippocampal and whole brain volumes are within normal ranges. Biomarkers (Aβ, T-tau, P-tau) are normal, and cognitive performance (MMSE 28) is intact. Fusiform gyrus shows mild atrophy, but other regions are unaffected.  \n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (Ventricular enlargement is concerning, but normal biomarkers and cognition suggest no current impairment.)",
  "timestamp": "2025-07-25T20:39:05.246439"
}