{
  "ptid_time": "133_S_0727_2008-03-11",
  "img_path": "/data/qiuhui/data/adni/images/133_S_0727/2008-03-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 68,299 mm³, 143.3% above the reference mean. With a Z-score of 3.28 (99.9th percentile), this represents profound enlargement; hippocampal volume measures 5,163 mm³, 27.4% below the reference mean. With a Z-score of -2.52 (0.6th percentile), this represents significant atrophy; whole brain volume measures 1,022,220 mm³, 4.9% above the reference mean. With a Z-score of 0.61 (73.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,856 mm³, 5.0% above the reference mean. With a Z-score of 0.31 (62.0th percentile), this represents normal volume ; fusiform gyrus volume measures 11,982 mm³, 29.6% below the reference mean. With a Z-score of -2.69 (0.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 12,908 mm³, 32.7% below the reference mean. With a Z-score of -2.84 (0.2th percentile), this represents significant atrophy. ",
  "text_data": "Age is 70.7 years. Gender is Female. Education: 12 years. MMSE: 20.0. Laboratory findings: Total Protein: 6.00 (significant reduced); GGT: 61.00 (profound elevated). APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement and significant atrophy in the hippocampus, fusiform gyrus, and middle temporal gyrus—key regions affected in Alzheimer's disease. The MMSE score of 20 indicates cognitive impairment, and the presence of two APOE4 alleles further increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T15:24:53.863462"
}