{
  "ptid_time": "014_S_4039_2011-06-02",
  "img_path": "/data/qiuhui/data/adni/images/014_S_4039/2011-06-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,913 mm³, 67.6% above the reference mean. With a Z-score of 0.90 (81.5th percentile), this represents normal volume ; hippocampal volume measures 6,471 mm³.; whole brain volume measures 935,155 mm³, 21.6% below the reference mean. With a Z-score of -3.99 (0.0th percentile), this represents profound atrophy; entorhinal cortex volume measures 3,089 mm³, 22.8% below the reference mean. With a Z-score of -2.00 (2.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,075 mm³, 32.5% below the reference mean. With a Z-score of -4.93 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 14,896 mm³.. ",
  "text_data": "Age is 55.9 years. Gender is Male. Education: 19 years. Handedness: Right. Race: White. Medical history: Musculoskeletal; Alcohol Abuse; Drug Abuse. MMSE: 21.0. MoCA: 17.0. Logical Memory: 1.0. Laboratory findings: Neutrophils: 77.00 (significant elevated); RBC: 5.50 (significant elevated); Neutrophils: 6.26 (significant elevated); Total Bilirubin: 1.00 (profound elevated); ALT (SGPT): 35.00 (significant elevated). APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.67 SUVR (profound elevated); Amyloid beta: 593.60 pg/mL (mild reduced); Total tau: 542.70 pg/mL (profound elevated); Phosphorylated tau: 57.04 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The data shows profound atrophy in whole brain, entorhinal cortex, and fusiform gyrus volumes, along with elevated biomarkers (Aβ, T-tau, P-tau, AV45). The cognitive scores (MMSE: 21, MoCA: 17) are below normal ranges, indicating significant cognitive impairment. These findings are consistent with neurodegenerative disease, likely Alzheimer's.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: High",
  "timestamp": "2025-07-25T23:49:47.018752"
}