{
  "ptid_time": "153_S_6237_2018-02-27",
  "img_path": "/data/qiuhui/data/adni/images/153_S_6237/2018-02-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 24,043 mm³, 7.6% above the reference mean. With a Z-score of 0.19 (57.6th percentile), this represents normal volume ; hippocampal volume measures 6,998 mm³, 8.9% below the reference mean. With a Z-score of -1.00 (15.8th percentile), this represents mild atrophy; whole brain volume measures 1,011,350 mm³, 1.7% below the reference mean. With a Z-score of -0.22 (41.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,758 mm³, 3.5% below the reference mean. With a Z-score of -0.27 (39.4th percentile), this represents normal volume ; fusiform gyrus volume measures 18,287 mm³, 0.4% above the reference mean. With a Z-score of 0.05 (51.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,437 mm³, 0.4% below the reference mean. With a Z-score of -0.04 (48.6th percentile), this represents normal volume . ",
  "text_data": "Age is 61.1 years. Gender is Female. Education: 20 years. Handedness: Right. Race: Asian. MMSE: 30.0. MoCA: 25.0. Logical Memory: 11.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.97 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows mild atrophy (Z-score -1.00, 15.8th percentile), which is a key biomarker for Alzheimer's pathology, while other brain regions are within normal ranges. The MoCA score (25/30) suggests mild cognitive impairment, but the MMSE (30/30) is normal, indicating possible early-stage cognitive changes. The absence of APOE4 and normal AV45 (amyloid PET) reduce the likelihood of advanced Alzheimer’s but do not rule out early neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting cognitive scores and normal amyloid imaging, but hippocampal atrophy supports MCI).",
  "timestamp": "2025-07-26T17:16:25.818990"
}