{
  "ptid_time": "016_S_6800_2019-08-19",
  "img_path": "/data/qiuhui/data/adni/images/016_S_6800/2019-08-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,087 mm³, 11.2% above the reference mean. With a Z-score of 0.30 (61.8th percentile), this represents normal volume ; hippocampal volume measures 4,781 mm³, 26.4% below the reference mean. With a Z-score of -2.11 (1.7th percentile), this represents significant atrophy; whole brain volume measures 809,946 mm³, 12.7% below the reference mean. With a Z-score of -1.53 (6.3th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,098 mm³, 39.4% below the reference mean. With a Z-score of -2.13 (1.7th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,021 mm³, 13.0% below the reference mean. With a Z-score of -0.97 (16.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 15,404 mm³, 14.6% below the reference mean. With a Z-score of -1.30 (9.8th percentile), this represents mild atrophy. ",
  "text_data": "Age is 87.5 years. Gender is Female. Education: 19 years. Handedness: Right. Race: White. MMSE: 29.0. MoCA: 20.0. Logical Memory: 6.0. Biomarker levels: Flobetaben (FBB): 1.68 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD), along with moderate whole-brain atrophy. The MMSE score of 29 is within the normal range, but the MoCA score of 20 suggests mild cognitive impairment (MCI). Given the age and the discrepancy between MMSE and MoCA, this likely reflects early AD pathology.  \n\n**Diagnosis:** **MCI (likely due to Alzheimer’s disease)**  \n**Confidence:** **Medium** (High confidence in atrophy patterns, but MoCA-MMSE discrepancy and lack of functional decline details limit certainty on dementia diagnosis.)",
  "timestamp": "2025-07-26T00:40:29.444202"
}