{
  "ptid_time": "141_S_0696_2007-09-29",
  "img_path": "/data/qiuhui/data/adni/images/141_S_0696/2007-09-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,921 mm³, 67.2% above the reference mean. With a Z-score of 1.54 (93.8th percentile), this represents moderate enlargement; hippocampal volume measures 6,145 mm³, 13.6% below the reference mean. With a Z-score of -1.25 (10.6th percentile), this represents mild atrophy; whole brain volume measures 839,874 mm³, 13.8% below the reference mean. With a Z-score of -1.74 (4.1th percentile), this represents moderate atrophy; entorhinal cortex volume measures 3,148 mm³, 14.3% below the reference mean. With a Z-score of -0.88 (19.0th percentile), this represents normal volume ; fusiform gyrus volume measures 12,438 mm³, 26.9% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy; middle temporal gyrus volume measures 12,567 mm³, 34.4% below the reference mean. With a Z-score of -2.99 (0.1th percentile), this represents significant atrophy. ",
  "text_data": "Age is 75.0 years. Gender is Female. Education: 12 years. MMSE: 22.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, fusiform gyrus, middle temporal gyrus) alongside moderate whole-brain atrophy and ventricular enlargement. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T16:46:31.421403"
}