{
  "ptid_time": "053_S_0389_2008-04-30",
  "img_path": "/data/qiuhui/data/adni/images/053_S_0389/2008-04-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 42,032 mm³, 49.8% above the reference mean. With a Z-score of 1.14 (87.3th percentile), this represents mild enlargement; hippocampal volume measures 4,960 mm³, 30.3% below the reference mean. With a Z-score of -2.78 (0.3th percentile), this represents significant atrophy; whole brain volume measures 1,043,140 mm³, 7.0% above the reference mean. With a Z-score of 0.88 (81.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,775 mm³, 24.4% below the reference mean. With a Z-score of -1.50 (6.7th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,703 mm³, 9.9% above the reference mean. With a Z-score of 0.90 (81.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,557 mm³, 8.4% below the reference mean. With a Z-score of -0.73 (23.3th percentile), this represents normal volume . ",
  "text_data": "Age is 73.5 years. Gender is Female. Education: 16 years. MMSE: 29.0. Logical Memory: 0.0. Laboratory findings: Total Protein: 8.00 (significant elevated). APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal atrophy (Z-score -2.78, 0.3rd percentile) and moderate entorhinal cortex atrophy (Z-score -1.50, 6.7th percentile), both key biomarkers for Alzheimer’s pathology. However, the MMSE score of 29 is within the normal range, suggesting no significant cognitive impairment at this time.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (given structural changes despite normal cognition, likely preclinical or early MCI stage).  \n\n**Confidence:** **Medium** (high confidence in structural findings, but clinical correlation is needed due to normal MMSE).",
  "timestamp": "2025-07-26T07:53:44.669683"
}