{
  "ptid_time": "012_S_0917_2006-12-01",
  "img_path": "/data/qiuhui/data/adni/images/012_S_0917/2006-12-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 13,932 mm³, 63.8% below the reference mean. With a Z-score of -1.53 (6.3th percentile), this represents moderate atrophy; hippocampal volume measures 7,174 mm³, 5.1% below the reference mean. With a Z-score of -0.50 (31.0th percentile), this represents normal volume ; whole brain volume measures 1,007,330 mm³, 6.7% below the reference mean. With a Z-score of -0.87 (19.3th percentile), this represents normal volume ; entorhinal cortex volume measures 3,310 mm³, 19.3% below the reference mean. With a Z-score of -1.31 (9.6th percentile), this represents mild atrophy; fusiform gyrus volume measures 14,951 mm³, 20.6% below the reference mean. With a Z-score of -1.76 (3.9th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 16,474 mm³, 22.8% below the reference mean. With a Z-score of -2.05 (2.0th percentile), this represents significant atrophy. ",
  "text_data": "Age is 70.2 years. Gender is Male. Education: 10 years. MMSE: 24.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging shows moderate to significant atrophy in key Alzheimer’s-related regions (ventricular volume, entorhinal cortex, fusiform gyrus, middle temporal gyrus), while hippocampal volume is normal. The MMSE score of 24 suggests mild cognitive impairment, and the absence of APOE4 reduces but does not eliminate Alzheimer’s risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Atrophy patterns and MMSE support MCI, but lack of APOE4 and normal hippocampal volume introduce some uncertainty.)",
  "timestamp": "2025-07-25T23:06:50.094312"
}