{
  "ptid_time": "012_S_4026_2013-06-10",
  "img_path": "/data/qiuhui/data/adni/images/012_S_4026/2013-06-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,308 mm³, 20.2% above the reference mean. With a Z-score of 0.48 (68.6th percentile), this represents normal volume ; hippocampal volume measures 7,067 mm³, 6.5% below the reference mean. With a Z-score of -0.64 (26.3th percentile), this represents normal volume ; whole brain volume measures 1,074,270 mm³, 0.5% below the reference mean. With a Z-score of -0.06 (47.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,875 mm³, 5.5% below the reference mean. With a Z-score of -0.37 (35.5th percentile), this represents normal volume ; fusiform gyrus volume measures 21,120 mm³, 12.1% above the reference mean. With a Z-score of 1.03 (84.9th percentile), this represents mild enlargement; middle temporal gyrus volume measures 21,619 mm³, 1.3% above the reference mean. With a Z-score of 0.12 (54.7th percentile), this represents normal volume . ",
  "text_data": "Age is 75.5 years. Gender is Male. Education: 16 years. MMSE: 29.0. MoCA: 30.0. Logical Memory: 17.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.21 SUVR (normal ); Amyloid beta: 550.70 pg/mL (mild reduced); Total tau: 208.30 pg/mL (normal ); Phosphorylated tau: 18.25 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges, with only mild deviations (e.g., slightly reduced hippocampal and entorhinal cortex volumes, mild fusiform gyrus enlargement). Cognitive scores (MMSE 29, MoCA 30) are intact, and biomarkers (Aβ mildly reduced, normal tau and AV45) do not strongly suggest Alzheimer’s pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mild Aβ reduction and subtle volume changes, but strong cognitive performance and lack of significant biomarker abnormalities)",
  "timestamp": "2025-07-25T23:11:02.351755"
}