{
  "ptid_time": "014_S_0563_2009-07-21",
  "img_path": "/data/qiuhui/data/adni/images/014_S_0563/2009-07-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 61,236 mm³, 30.2% above the reference mean. With a Z-score of 0.88 (81.0th percentile), this represents normal volume ; hippocampal volume measures 4,976 mm³, 28.6% below the reference mean. With a Z-score of -2.47 (0.7th percentile), this represents significant atrophy; whole brain volume measures 964,719 mm³, 6.3% below the reference mean. With a Z-score of -0.82 (20.6th percentile), this represents normal volume ; entorhinal cortex volume measures 2,399 mm³, 39.6% below the reference mean. With a Z-score of -2.59 (0.5th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,962 mm³, 11.6% below the reference mean. With a Z-score of -1.01 (15.7th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,790 mm³, 16.8% below the reference mean. With a Z-score of -1.50 (6.6th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 83.6 years. Gender is Male. Education: 18 years. MMSE: 21.0. Logical Memory: 5.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). The MMSE score of 21 suggests cognitive impairment, and the absence of APOE4 does not rule out AD, especially given the structural changes.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T23:45:40.720603"
}