{
  "ptid_time": "041_S_1368_2009-03-16",
  "img_path": "/data/qiuhui/data/adni/images/041_S_1368/2009-03-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 52,499 mm³, 87.0% above the reference mean. With a Z-score of 1.99 (97.7th percentile), this represents moderate enlargement; hippocampal volume measures 4,509 mm³, 36.6% below the reference mean. With a Z-score of -3.36 (0.0th percentile), this represents profound atrophy; whole brain volume measures 781,039 mm³, 19.9% below the reference mean. With a Z-score of -2.50 (0.6th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,915 mm³, 47.9% below the reference mean. With a Z-score of -2.94 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 10,068 mm³, 40.8% below the reference mean. With a Z-score of -3.72 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 9,027 mm³, 52.9% below the reference mean. With a Z-score of -4.59 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 77.2 years. Gender is Female. Education: 18 years. MMSE: 5.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in multiple brain regions critical for memory and cognition (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside significant whole-brain atrophy and ventricular enlargement. The MMSE score of 5 indicates severe cognitive impairment. The absence of APOE4 does not rule out Alzheimer's given the structural and clinical severity.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease, given the pattern of atrophy).  \n\n**Confidence:** High.",
  "timestamp": "2025-07-26T07:05:06.269965"
}