{
  "ptid_time": "133_S_0638_2008-03-06",
  "img_path": "/data/qiuhui/data/adni/images/133_S_0638/2008-03-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 58,812 mm³, 25.1% above the reference mean. With a Z-score of 0.73 (76.7th percentile), this represents normal volume ; hippocampal volume measures 4,001 mm³, 42.6% below the reference mean. With a Z-score of -3.68 (0.0th percentile), this represents profound atrophy; whole brain volume measures 838,385 mm³, 18.5% below the reference mean. With a Z-score of -2.43 (0.8th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,845 mm³, 53.5% below the reference mean. With a Z-score of -3.50 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,507 mm³, 36.3% below the reference mean. With a Z-score of -3.14 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 12,984 mm³, 35.6% below the reference mean. With a Z-score of -3.19 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 84.6 years. Gender is Male. Education: 17 years. MMSE: 18.0. Laboratory findings: Total Bilirubin: 0.80 (significant elevated); Serum Glucose: 65.00 (significant reduced). APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) alongside significant whole-brain atrophy, consistent with advanced neurodegeneration. The MMSE score of 18 indicates moderate cognitive impairment, and the presence of two APOE4 alleles further supports Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T15:23:35.276961"
}