{
  "ptid_time": "002_S_1268_2009-03-04",
  "img_path": "/data/qiuhui/data/adni/images/002_S_1268/2009-03-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 80,993 mm³, 72.3% above the reference mean. With a Z-score of 2.10 (98.2th percentile), this represents significant enlargement; hippocampal volume measures 6,146 mm³, 11.8% below the reference mean. With a Z-score of -1.02 (15.4th percentile), this represents mild atrophy; whole brain volume measures 1,040,270 mm³, 1.1% above the reference mean. With a Z-score of 0.14 (55.6th percentile), this represents normal volume ; entorhinal cortex volume measures 4,720 mm³, 18.9% above the reference mean. With a Z-score of 1.24 (89.2th percentile), this represents mild enlargement; fusiform gyrus volume measures 17,504 mm³, 3.1% below the reference mean. With a Z-score of -0.27 (39.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,634 mm³, 2.3% above the reference mean. With a Z-score of 0.21 (58.1th percentile), this represents normal volume . ",
  "text_data": "Age is 84.7 years. Gender is Male. Education: 20 years. MMSE: 30.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 496.30 pg/mL (mild reduced); Total tau: 171.80 pg/mL (normal ); Phosphorylated tau: 16.29 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant ventricular enlargement (Z-score 2.10) and mild hippocampal atrophy (Z-score -1.02), which are structural changes often seen in neurodegenerative disorders. However, cognitive performance (MMSE 30) is intact, Aβ is only mildly reduced, and tau biomarkers are normal, suggesting no significant functional impairment.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (structural changes present but no dementia-level cognitive decline)  \n**Confidence:** **Medium** (biomarkers and imaging suggest early neurodegeneration, but clinical symptoms are not yet pronounced)",
  "timestamp": "2025-07-25T20:15:31.958484"
}