{
  "ptid_time": "067_S_0059_2010-12-10",
  "img_path": "/data/qiuhui/data/adni/images/067_S_0059/2010-12-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,066 mm³, 49.9% below the reference mean. With a Z-score of -1.14 (12.7th percentile), this represents mild atrophy; hippocampal volume measures 6,798 mm³, 4.4% below the reference mean. With a Z-score of -0.41 (34.2th percentile), this represents normal volume ; whole brain volume measures 842,989 mm³, 13.5% below the reference mean. With a Z-score of -1.70 (4.5th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,816 mm³, 23.3% below the reference mean. With a Z-score of -1.43 (7.6th percentile), this represents mild atrophy; fusiform gyrus volume measures 11,687 mm³, 31.3% below the reference mean. With a Z-score of -2.85 (0.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,712 mm³, 28.5% below the reference mean. With a Z-score of -2.47 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 75.9 years. Gender is Female. Education: 13 years. Handedness: Right. Race: Black or African American. Medical history: Cardiovascular; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 27.0. MoCA: 20.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.99 SUVR (normal ); Amyloid beta: 1616.00 pg/mL (moderate elevated); Total tau: 180.10 pg/mL (normal ); Phosphorylated tau: 16.22 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the fusiform gyrus and middle temporal gyrus, along with mild-to-moderate atrophy in other regions. The MMSE is normal (27/30), but the MoCA (20/30) suggests mild cognitive impairment. Biomarkers indicate moderate Aβ elevation but normal tau and AV45, which may suggest early Alzheimer’s pathology without significant neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting MMSE/MoCA scores and moderate Aβ elevation without tauopathy)",
  "timestamp": "2025-07-26T08:24:02.904746"
}