{
  "ptid_time": "016_S_0702_2011-08-29",
  "img_path": "/data/qiuhui/data/adni/images/016_S_0702/2011-08-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 118,676 mm³, 142.8% above the reference mean. With a Z-score of 12.93 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,427 mm³, 30.5% below the reference mean. With a Z-score of -3.32 (0.0th percentile), this represents profound atrophy; whole brain volume measures 863,741 mm³, 13.8% below the reference mean. With a Z-score of -2.35 (0.9th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,270 mm³, 67.9% below the reference mean. With a Z-score of -3.49 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 15,215 mm³, 9.7% below the reference mean. With a Z-score of -1.12 (13.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 18,105 mm³, 4.0% below the reference mean. With a Z-score of -0.61 (27.1th percentile), this represents normal volume . ",
  "text_data": "Age is 90.0 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Malignancy; Major Surgical Procedures. MMSE: 21.0. MoCA: 17.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex) and significant whole-brain atrophy, alongside severe ventricular enlargement. The cognitive scores (MMSE 21, MoCA 17) are consistent with moderate cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T00:04:41.844549"
}