{
  "ptid_time": "016_S_4951_2012-10-01",
  "img_path": "/data/qiuhui/data/adni/images/016_S_4951/2012-10-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,854 mm³, 22.1% below the reference mean. With a Z-score of -0.51 (30.6th percentile), this represents normal volume ; whole brain volume measures 1,012,300 mm³, 3.9% above the reference mean. With a Z-score of 0.49 (68.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,289 mm³, 10.5% below the reference mean. With a Z-score of -0.64 (26.1th percentile), this represents normal volume ; fusiform gyrus volume measures 17,661 mm³, 3.8% above the reference mean. With a Z-score of 0.35 (63.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,933 mm³, 14.4% above the reference mean. With a Z-score of 1.25 (89.5th percentile), this represents mild enlargement. ",
  "text_data": "Age is 71.9 years. Gender is Female. Education: 14 years. MMSE: 29.0. MoCA: 27.0. Logical Memory: 16.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.03 SUVR (normal ); Amyloid beta: 1024.00 pg/mL (normal ); Total tau: 119.40 pg/mL (moderate reduced); Phosphorylated tau: 12.12 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges, with only mild deviations (e.g., entorhinal cortex slightly below mean but still normal). Cognitive scores (MMSE 29, MoCA 27) are intact, and biomarkers (Aβ normal, AV45 normal) do not suggest amyloid pathology. Reduced T-tau and P-tau are atypical for Alzheimer’s but may indicate non-AD pathology or measurement variability.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to atypical tau profile but otherwise normal findings)",
  "timestamp": "2025-07-26T00:33:36.424094"
}