{
  "ptid_time": "021_S_0984_2007-12-13",
  "img_path": "/data/qiuhui/data/adni/images/021_S_0984/2007-12-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 85,797 mm³, 122.7% above the reference mean. With a Z-score of 2.94 (99.8th percentile), this represents significant enlargement; hippocampal volume measures 7,626 mm³, 0.9% above the reference mean. With a Z-score of 0.09 (53.4th percentile), this represents normal volume ; whole brain volume measures 1,076,680 mm³, 0.3% below the reference mean. With a Z-score of -0.03 (48.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,523 mm³, 14.1% below the reference mean. With a Z-score of -0.96 (17.0th percentile), this represents normal volume ; fusiform gyrus volume measures 17,323 mm³, 8.0% below the reference mean. With a Z-score of -0.69 (24.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,777 mm³, 6.7% above the reference mean. With a Z-score of 0.61 (72.8th percentile), this represents normal volume . ",
  "text_data": "Age is 77.6 years. Gender is Male. Education: 14 years. MMSE: 30.0. Logical Memory: 12.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 250.10 pg/mL (significant reduced); Total tau: 354.20 pg/mL (mild elevated); Phosphorylated tau: 37.41 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 2.94), which is a marker of brain atrophy, along with reduced Aβ and elevated P-tau, strongly suggesting Alzheimer's pathology. However, hippocampal volume is normal, and MMSE is intact (30/30), indicating preserved cognitive function despite biomarker abnormalities.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment, likely due to Alzheimer’s pathology)**  \n**Confidence:** **Medium** (Biomarkers strongly suggest Alzheimer’s, but cognitive performance is still normal, making early MCI more likely than full dementia.)",
  "timestamp": "2025-07-26T01:35:30.349170"
}