{
  "ptid_time": "019_S_4252_2012-10-23",
  "img_path": "/data/qiuhui/data/adni/images/019_S_4252/2012-10-23/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 67,608 mm³, 82.9% above the reference mean. With a Z-score of 2.24 (98.7th percentile), this represents significant enlargement; hippocampal volume measures 4,482 mm³, 31.0% below the reference mean. With a Z-score of -2.48 (0.7th percentile), this represents significant atrophy; whole brain volume measures 882,984 mm³, 4.9% below the reference mean. With a Z-score of -0.58 (27.9th percentile), this represents normal volume ; entorhinal cortex volume measures 2,289 mm³, 33.9% below the reference mean. With a Z-score of -1.83 (3.4th percentile), this represents moderate atrophy; fusiform gyrus volume measures 13,511 mm³, 16.1% below the reference mean. With a Z-score of -1.21 (11.3th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,266 mm³, 9.8% below the reference mean. With a Z-score of -0.87 (19.2th percentile), this represents normal volume . ",
  "text_data": "Age is 87.5 years. Gender is Female. Education: 16 years. MMSE: 18.0. MoCA: 14.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal atrophy (Z-score -2.48) and moderate entorhinal cortex atrophy (Z-score -1.83), both key regions affected in Alzheimer's disease. The cognitive scores (MMSE 18, MoCA 14) are well below normal, consistent with dementia. Ventricular enlargement further supports neurodegeneration.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T01:03:02.609713"
}