{
  "ptid_time": "067_S_1185_2007-08-07",
  "img_path": "/data/qiuhui/data/adni/images/067_S_1185/2007-08-07/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,326 mm³, 37.6% above the reference mean. With a Z-score of 0.89 (81.4th percentile), this represents normal volume ; hippocampal volume measures 5,535 mm³, 31.0% below the reference mean. With a Z-score of -3.10 (0.1th percentile), this represents profound atrophy; whole brain volume measures 909,576 mm³, 19.8% below the reference mean. With a Z-score of -2.81 (0.3th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,726 mm³, 36.1% below the reference mean. With a Z-score of -2.50 (0.6th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,943 mm³, 40.0% below the reference mean. With a Z-score of -3.33 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 14,833 mm³, 33.8% below the reference mean. With a Z-score of -2.79 (0.3th percentile), this represents significant atrophy. ",
  "text_data": "Age is 62.5 years. Gender is Male. Education: 16 years. MMSE: 16.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits profound atrophy in the hippocampus and fusiform gyrus, along with significant atrophy in the whole brain, entorhinal cortex, and middle temporal gyrus—all key regions affected in Alzheimer’s disease. The MMSE score of 16 indicates severe cognitive impairment, consistent with dementia. The presence of an APOE4 allele further supports Alzheimer’s pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T08:32:10.649394"
}