{
  "ptid_time": "116_S_1271_2011-04-04",
  "img_path": "/data/qiuhui/data/adni/images/116_S_1271/2011-04-04/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 4,046 mm³, 46.5% below the reference mean. With a Z-score of -4.53 (0.0th percentile), this represents profound atrophy; whole brain volume measures 721,233 mm³, 33.2% below the reference mean. With a Z-score of -4.31 (0.0th percentile), this represents profound atrophy; entorhinal cortex volume measures 1,822 mm³, 55.6% below the reference mean. With a Z-score of -3.77 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,640 mm³, 38.2% below the reference mean. With a Z-score of -3.25 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 10,776 mm³, 49.5% below the reference mean. With a Z-score of -4.45 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 75.2 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Endocrine-Metabolic; Gastrointestinal; Hematopoietic-Lymphatic; Renal-Genitourinary; Smoking; Malignancy; Major Surgical Procedures. MMSE: 13.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The data shows profound atrophy in multiple brain regions critical for memory and cognition (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), with Z-scores far below normal. Combined with a very low MMSE score (13/30) and APOE4 positivity, this strongly suggests advanced neurodegenerative disease.  \nDiagnosis: **Dementia** (likely Alzheimer’s disease given the pattern of atrophy and APOE4 status).  \nConfidence: **High**.",
  "timestamp": "2025-07-26T12:04:40.215692"
}