{
  "ptid_time": "022_S_4805_2014-07-11",
  "img_path": "/data/qiuhui/data/adni/images/022_S_4805/2014-07-11/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 6,189 mm³, 13.0% below the reference mean. With a Z-score of -1.19 (11.6th percentile), this represents mild atrophy; whole brain volume measures 1,065,460 mm³, 9.3% above the reference mean. With a Z-score of 1.17 (88.0th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,166 mm³, 13.8% below the reference mean. With a Z-score of -0.85 (19.8th percentile), this represents normal volume ; fusiform gyrus volume measures 17,183 mm³, 1.0% above the reference mean. With a Z-score of 0.09 (53.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,330 mm³, 4.4% below the reference mean. With a Z-score of -0.38 (35.2th percentile), this represents normal volume . ",
  "text_data": "Age is 73.9 years. Gender is Female. Education: 20 years. MMSE: 26.0. MoCA: 24.0. Logical Memory: 6.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.45 SUVR (significant elevated); Amyloid beta: 1023.00 pg/mL (normal ); Total tau: 392.50 pg/mL (moderate elevated); Phosphorylated tau: 42.39 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows mild hippocampal atrophy (Z-score -1.19) and elevated biomarkers (P-tau, AV45), suggesting Alzheimer's pathology, but Aβ is normal, which is atypical for typical AD. Cognitive scores (MMSE 26, MoCA 24) are borderline, with no severe impairment.  \n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to non-amyloid or mixed pathology given normal Aβ but elevated tau/PET).  \n**Confidence:** **Medium** (biomarker and imaging findings support neurodegeneration, but normal Aβ complicates a typical AD diagnosis).",
  "timestamp": "2025-07-26T02:21:53.405316"
}