{
  "ptid_time": "027_S_0485_2007-05-30",
  "img_path": "/data/qiuhui/data/adni/images/027_S_0485/2007-05-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,326 mm³, 47.6% above the reference mean. With a Z-score of 1.13 (87.1th percentile), this represents mild enlargement; hippocampal volume measures 6,787 mm³, 15.4% below the reference mean. With a Z-score of -1.54 (6.1th percentile), this represents moderate atrophy; whole brain volume measures 957,885 mm³, 15.6% below the reference mean. With a Z-score of -2.20 (1.4th percentile), this represents significant atrophy; entorhinal cortex volume measures 4,994 mm³, 17.2% above the reference mean. With a Z-score of 1.19 (88.2th percentile), this represents mild enlargement; fusiform gyrus volume measures 13,484 mm³, 32.3% below the reference mean. With a Z-score of -2.68 (0.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 17,720 mm³, 20.9% below the reference mean. With a Z-score of -1.72 (4.2th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 65.4 years. Gender is Male. Education: 16 years. MMSE: 24.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in whole brain volume (-2.20 Z-score) and fusiform gyrus (-2.68 Z-score), along with moderate hippocampal atrophy (-1.54 Z-score), which are strongly associated with Alzheimer’s pathology. The MMSE score of 24 suggests mild cognitive impairment, and the presence of two APOE4 alleles increases Alzheimer’s risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T03:39:49.364199"
}