{
  "ptid_time": "041_S_4138_2013-09-11",
  "img_path": "/data/qiuhui/data/adni/images/041_S_4138/2013-09-11/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 4,217 mm³, 40.1% below the reference mean. With a Z-score of -22.13 (0.0th percentile), this represents profound atrophy; whole brain volume measures 886,454 mm³, 2.6% below the reference mean. With a Z-score of -0.29 (38.7th percentile), this represents normal volume . ",
  "text_data": "Age is 90.4 years. Gender is Female. Education: 14 years. MMSE: 22.0. MoCA: 22.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.01 SUVR (normal ); Total tau: 393.90 pg/mL (moderate elevated); Phosphorylated tau: 34.15 pg/mL (moderate elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows profound atrophy (40.1% below mean, Z-score -22.13), strongly suggestive of neurodegeneration, while whole brain volume is normal. Cognitive scores (MMSE 22, MoCA 22) are borderline impaired, and biomarkers (elevated T-tau/P-tau, normal AV45) support Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High** (due to severe hippocampal atrophy, biomarker profile, and borderline-low cognitive scores in a 90-year-old patient).",
  "timestamp": "2025-07-26T07:13:11.521041"
}