{
  "ptid_time": "032_S_0718_2006-07-12",
  "img_path": "/data/qiuhui/data/adni/images/032_S_0718/2006-07-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 39,550 mm³, 7.0% above the reference mean. With a Z-score of 0.19 (57.5th percentile), this represents normal volume ; hippocampal volume measures 7,011 mm³, 7.9% above the reference mean. With a Z-score of 0.64 (73.8th percentile), this represents normal volume ; whole brain volume measures 975,200 mm³, 5.1% above the reference mean. With a Z-score of 0.61 (72.8th percentile), this represents normal volume ; entorhinal cortex volume measures 4,004 mm³, 15.6% above the reference mean. With a Z-score of 0.84 (80.1th percentile), this represents normal volume ; fusiform gyrus volume measures 16,863 mm³, 4.7% above the reference mean. With a Z-score of 0.35 (63.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,302 mm³, 9.6% below the reference mean. With a Z-score of -0.85 (19.7th percentile), this represents normal volume . ",
  "text_data": "Age is 80.4 years. Gender is Female. Education: 18 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Endocrine-Metabolic; Hematopoietic-Lymphatic; Allergies or Drug Sensitivities; Malignancy; Major Surgical Procedures. MMSE: 27.0. Logical Memory: 6.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 803.50 pg/mL (normal ); Total tau: 387.80 pg/mL (moderate elevated); Phosphorylated tau: 40.41 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volume measurements (ventricular, hippocampal, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) are all within normal ranges, with most structures above the reference mean. The MMSE score of 27 is within the normal range (≥26), and Aβ levels are normal. However, elevated T-tau (moderate) and P-tau (significant) suggest neurodegeneration, which may indicate early pathological changes despite preserved cognitive function.  \n\nDiagnosis: CN (Cognitively Normal)  \nConfidence: Medium (due to conflicting biomarkers—normal Aβ but elevated tau—suggesting possible preclinical AD, but no cognitive impairment yet)",
  "timestamp": "2025-07-26T04:57:41.775697"
}