{
  "ptid_time": "098_S_0667_2012-07-28",
  "img_path": "/data/qiuhui/data/adni/images/098_S_0667/2012-07-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 103,354 mm³, 168.3% above the reference mean. With a Z-score of 4.03 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,963 mm³, 7.9% below the reference mean. With a Z-score of -0.77 (22.1th percentile), this represents normal volume ; whole brain volume measures 1,000,840 mm³, 7.3% below the reference mean. With a Z-score of -0.94 (17.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,397 mm³, 41.5% below the reference mean. With a Z-score of -2.82 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 12,377 mm³, 34.3% below the reference mean. With a Z-score of -2.92 (0.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 12,545 mm³, 41.2% below the reference mean. With a Z-score of -3.70 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 75.0 years. Gender is Male. Education: 20 years. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (indicating significant brain atrophy) and severe atrophy in the entorhinal cortex, fusiform gyrus, and middle temporal gyrus—key regions affected in Alzheimer’s disease. The hippocampal volume is within normal limits, but the widespread cortical atrophy and APOE4 carrier status strongly suggest neurodegenerative pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T10:42:00.042236"
}