{
  "ptid_time": "022_S_1097_2012-01-17",
  "img_path": "/data/qiuhui/data/adni/images/022_S_1097/2012-01-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 40,785 mm³, 5.9% above the reference mean. With a Z-score of 0.14 (55.6th percentile), this represents normal volume ; hippocampal volume measures 4,750 mm³, 37.2% below the reference mean. With a Z-score of -3.63 (0.0th percentile), this represents profound atrophy; whole brain volume measures 887,691 mm³, 17.8% below the reference mean. With a Z-score of -2.31 (1.1th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,300 mm³, 43.9% below the reference mean. With a Z-score of -2.98 (0.1th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,672 mm³, 22.1% below the reference mean. With a Z-score of -1.88 (3.0th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,833 mm³, 25.8% below the reference mean. With a Z-score of -2.32 (1.0th percentile), this represents significant atrophy. ",
  "text_data": "Age is 78.0 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Psychiatric; Dermatologic-Connective Tissue; Renal-Genitourinary; Smoking. MMSE: 20.0. MoCA: 19.0. Logical Memory: 2.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows profound hippocampal atrophy (Z-score -3.63) and significant atrophy in the entorhinal cortex, whole brain, and middle temporal gyrus, which are hallmark structural changes in Alzheimer's disease. The cognitive scores (MMSE 20, MoCA 19) indicate moderate cognitive impairment, consistent with dementia rather than MCI.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T02:09:16.496585"
}