{
  "ptid_time": "011_S_0010_2006-05-09",
  "img_path": "/data/qiuhui/data/adni/images/011_S_0010/2006-05-09/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 29,616 mm³, 5.5% above the reference mean. With a Z-score of 0.13 (55.0th percentile), this represents normal volume ; hippocampal volume measures 5,319 mm³, 25.2% below the reference mean. With a Z-score of -2.31 (1.0th percentile), this represents significant atrophy; whole brain volume measures 989,045 mm³, 1.5% above the reference mean. With a Z-score of 0.19 (57.4th percentile), this represents normal volume ; entorhinal cortex volume measures 2,419 mm³, 34.1% below the reference mean. With a Z-score of -2.10 (1.8th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,892 mm³, 6.6% below the reference mean. With a Z-score of -0.60 (27.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,595 mm³, 3.0% below the reference mean. With a Z-score of -0.26 (39.7th percentile), this represents normal volume . ",
  "text_data": "Age is 74.4 years. Gender is Female. Education: 12 years. MMSE: 26.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in the hippocampus (Z-score -2.31, 1st percentile) and entorhinal cortex (Z-score -2.10, 1.8th percentile), which are key regions affected in Alzheimer's disease. The MMSE score of 26 is borderline, suggesting mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology)  \n**Confidence:** **Medium** (due to borderline MMSE and lack of detailed clinical history, but strong imaging support for early neurodegeneration)",
  "timestamp": "2025-07-25T22:38:07.574490"
}