{
  "ptid_time": "014_S_4079_2012-06-21",
  "img_path": "/data/qiuhui/data/adni/images/014_S_4079/2012-06-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,489 mm³, 0.7% above the reference mean. With a Z-score of 0.02 (50.7th percentile), this represents normal volume ; hippocampal volume measures 5,455 mm³, 29.0% below the reference mean. With a Z-score of -3.26 (0.1th percentile), this represents profound atrophy; whole brain volume measures 1,012,220 mm³, 1.6% below the reference mean. With a Z-score of -0.20 (41.9th percentile), this represents normal volume ; entorhinal cortex volume measures 2,299 mm³, 40.9% below the reference mean. With a Z-score of -3.17 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 12,876 mm³, 29.3% below the reference mean. With a Z-score of -3.30 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 15,707 mm³, 23.5% below the reference mean. With a Z-score of -2.08 (1.9th percentile), this represents significant atrophy. ",
  "text_data": "Age is 65.5 years. Gender is Female. Education: 20 years. MMSE: 24.0. MoCA: 19.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus, entorhinal cortex, fusiform gyrus, and significant atrophy in the middle temporal gyrus—key regions affected in Alzheimer's disease. The cognitive scores (MMSE 24, MoCA 19) indicate mild cognitive impairment, but the severe atrophy suggests progression toward dementia.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**  \n\n*(The combination of structural atrophy in AD-vulnerable regions and borderline cognitive scores strongly supports dementia, with APOE4 further increasing risk.)*",
  "timestamp": "2025-07-25T23:51:32.987916"
}