{
  "ptid_time": "099_S_6175_2018-03-16",
  "img_path": "/data/qiuhui/data/adni/images/099_S_6175/2018-03-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 16,363 mm³, 26.7% below the reference mean. With a Z-score of -0.67 (25.2th percentile), this represents normal volume ; hippocampal volume measures 7,340 mm³, 4.5% below the reference mean. With a Z-score of -0.50 (30.8th percentile), this represents normal volume ; whole brain volume measures 1,036,800 mm³, 0.7% above the reference mean. With a Z-score of 0.09 (53.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,330 mm³, 14.5% below the reference mean. With a Z-score of -1.12 (13.1th percentile), this represents mild atrophy; fusiform gyrus volume measures 16,284 mm³, 10.6% below the reference mean. With a Z-score of -1.19 (11.7th percentile), this represents mild atrophy; middle temporal gyrus volume measures 23,314 mm³, 13.6% above the reference mean. With a Z-score of 1.21 (88.7th percentile), this represents mild enlargement. ",
  "text_data": "Age is 69.3 years. Gender is Female. Education: 18 years. Handedness: Right. Race: White. MMSE: 28.0. MoCA: 25.0. Logical Memory: 16.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.52 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows mild atrophy in the entorhinal cortex and fusiform gyrus, which are regions often affected in early Alzheimer's disease. However, hippocampal and whole brain volumes are within normal ranges, and cognitive scores (MMSE 28, MoCA 25) are only mildly reduced, suggesting no significant functional impairment. The presence of APOE4 and elevated AV45 (amyloid PET) indicates increased Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarkers—some atrophy but preserved cognition and hippocampal volume)",
  "timestamp": "2025-07-26T11:12:21.823087"
}