{
  "ptid_time": "009_S_2381_2011-12-08",
  "img_path": "/data/qiuhui/data/adni/images/009_S_2381/2011-12-08/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 5,576 mm³, 30.5% below the reference mean. With a Z-score of -3.05 (0.1th percentile), this represents profound atrophy; whole brain volume measures 1,168,090 mm³, 3.0% above the reference mean. With a Z-score of 0.42 (66.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,861 mm³, 32.9% below the reference mean. With a Z-score of -2.28 (1.1th percentile), this represents significant atrophy; fusiform gyrus volume measures 21,367 mm³, 7.3% above the reference mean. With a Z-score of 0.61 (72.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,605 mm³, 0.9% above the reference mean. With a Z-score of 0.07 (52.8th percentile), this represents normal volume . ",
  "text_data": "Age is 69.6 years. Gender is Male. Education: 16 years. MMSE: 26.0. MoCA: 24.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The patient shows profound hippocampal atrophy (Z-score -3.05) and significant entorhinal cortex atrophy (Z-score -2.28), both strongly associated with Alzheimer's pathology. Despite relatively preserved global cognition (MMSE 26, MoCA 24), the presence of two APOE4 alleles increases Alzheimer's risk.  \nDiagnosis: **MCI (likely due to Alzheimer's disease)**  \nConfidence: **High**  \n\n(Structural atrophy in key memory regions with preserved global function fits MCI, while APOE4 status and severity of medial temporal atrophy strongly suggest underlying AD pathology.)",
  "timestamp": "2025-07-25T22:17:11.023144"
}