{
  "ptid_time": "002_S_0816_2006-08-30",
  "img_path": "/data/qiuhui/data/adni/images/002_S_0816/2006-08-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,085 mm³, 19.3% below the reference mean. With a Z-score of -0.46 (32.2th percentile), this represents normal volume ; whole brain volume measures 1,081,720 mm³, 0.2% above the reference mean. With a Z-score of 0.03 (51.1th percentile), this represents normal volume . ",
  "text_data": "Age is 70.8 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Dermatologic-Connective Tissue; Endocrine-Metabolic; Renal-Genitourinary; Alcohol Abuse; Smoking; Major Surgical Procedures. MMSE: 26.0. Logical Memory: 1.0. APOEε4 alleles: 2.0. Biomarker levels: Amyloid beta: 527.40 pg/mL (mild reduced); Total tau: 281.40 pg/mL (normal ); Phosphorylated tau: 27.24 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The brain volumes (ventricular and whole brain) are within normal ranges, and the MMSE score of 26 is borderline but not strongly indicative of cognitive impairment. However, the presence of two APOE4 alleles and mildly reduced Aβ suggests increased Alzheimer's risk, though tau levels are normal.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to borderline MMSE and biomarker findings, but lack of clear dementia-level impairment)",
  "timestamp": "2025-07-25T20:06:41.463223"
}