{
  "ptid_time": "052_S_4944_2019-07-18",
  "img_path": "/data/qiuhui/data/adni/images/052_S_4944/2019-07-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 27,715 mm³, 28.0% below the reference mean. With a Z-score of -0.67 (25.1th percentile), this represents normal volume ; hippocampal volume measures 7,449 mm³, 1.5% below the reference mean. With a Z-score of -0.14 (44.3th percentile), this represents normal volume ; whole brain volume measures 988,862 mm³, 8.4% below the reference mean. With a Z-score of -1.09 (13.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,420 mm³, 7.8% above the reference mean. With a Z-score of 0.53 (70.1th percentile), this represents normal volume ; fusiform gyrus volume measures 19,766 mm³, 4.9% above the reference mean. With a Z-score of 0.42 (66.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,015 mm³, 1.5% below the reference mean. With a Z-score of -0.14 (44.6th percentile), this represents normal volume . ",
  "text_data": "Age is 74.5 years. Gender is Male. Education: 14 years. MMSE: 25.0. MoCA: 19.0. Logical Memory: 4.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild whole-brain atrophy (Z-score -1.09, 13.8th percentile), but hippocampal and other key regional volumes are within normal ranges. The MMSE (25) is borderline, while the MoCA (19) suggests mild cognitive impairment. The presence of one APOE4 allele increases Alzheimer’s risk but is not definitive.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Cognitive scores indicate impairment, but structural changes are not yet severe enough for dementia.)",
  "timestamp": "2025-07-26T07:51:45.650180"
}