{
  "ptid_time": "027_S_2245_2013-01-22",
  "img_path": "/data/qiuhui/data/adni/images/027_S_2245/2013-01-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 16,769 mm³, 10.0% below the reference mean. With a Z-score of -0.28 (38.8th percentile), this represents normal volume ; hippocampal volume measures 8,659 mm³, 10.9% above the reference mean. With a Z-score of 1.52 (93.5th percentile), this represents moderate enlargement; whole brain volume measures 1,024,630 mm³, 1.5% below the reference mean. With a Z-score of -0.18 (42.7th percentile), this represents normal volume ; entorhinal cortex volume measures 4,207 mm³, 13.8% above the reference mean. With a Z-score of 1.08 (86.1th percentile), this represents mild enlargement; fusiform gyrus volume measures 18,242 mm³, 1.0% below the reference mean. With a Z-score of -0.09 (46.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,731 mm³, 5.8% above the reference mean. With a Z-score of 0.48 (68.5th percentile), this represents normal volume . ",
  "text_data": "Age is 59.0 years. Gender is Female. Education: 20 years. Handedness: Right. Race: White. Medical history: Psychiatric; Dermatologic-Connective Tissue; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 29.0. MoCA: 28.0. Logical Memory: 11.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.06 SUVR (normal ); Amyloid beta: 1037.00 pg/mL (normal ); Total tau: 236.30 pg/mL (normal ); Phosphorylated tau: 20.58 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show normal or above-average volumes in key regions (hippocampus, entorhinal cortex, middle temporal gyrus), with no significant atrophy. Biomarkers (Aβ, T-tau, P-tau, AV45) are normal, and cognitive scores (MMSE 29, MoCA 28) are intact. The presence of two APOE4 alleles increases Alzheimer's risk but does not currently indicate pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T03:54:27.099770"
}