{
  "ptid_time": "041_S_4138_2012-03-28",
  "img_path": "/data/qiuhui/data/adni/images/041_S_4138/2012-03-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,300 mm³, 19.8% above the reference mean. With a Z-score of 0.54 (70.4th percentile), this represents normal volume ; hippocampal volume measures 4,558 mm³, 29.8% below the reference mean. With a Z-score of -2.39 (0.8th percentile), this represents significant atrophy; whole brain volume measures 900,172 mm³, 3.0% below the reference mean. With a Z-score of -0.36 (35.9th percentile), this represents normal volume . ",
  "text_data": "Age is 88.9 years. Gender is Female. Education: 14 years. MMSE: 23.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The hippocampal volume shows significant atrophy (Z-score -2.39, 0.8th percentile), which is a strong biomarker for Alzheimer's pathology, while ventricular and whole brain volumes are within normal ranges. The MMSE score of 23.0 suggests mild cognitive impairment, and the absence of APOE4 does not rule out AD given the structural findings.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: Medium (clinical correlation and biomarker support, but no CSF or PET confirmation)",
  "timestamp": "2025-07-26T07:12:55.929746"
}