{
  "ptid_time": "100_S_1062_2006-11-13",
  "img_path": "/data/qiuhui/data/adni/images/100_S_1062/2006-11-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,112 mm³, 2.3% above the reference mean. With a Z-score of 0.07 (52.7th percentile), this represents normal volume ; hippocampal volume measures 6,400 mm³, 8.2% below the reference mean. With a Z-score of -0.70 (24.1th percentile), this represents normal volume ; whole brain volume measures 1,080,050 mm³, 4.9% above the reference mean. With a Z-score of 0.65 (74.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,569 mm³, 10.1% below the reference mean. With a Z-score of -0.66 (25.5th percentile), this represents normal volume ; fusiform gyrus volume measures 17,377 mm³, 3.8% below the reference mean. With a Z-score of -0.33 (37.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,472 mm³, 11.4% above the reference mean. With a Z-score of 1.02 (84.7th percentile), this represents mild enlargement. ",
  "text_data": "Age is 81.9 years. Gender is Male. Education: 12 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 24.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 424.70 pg/mL (moderate reduced); Total tau: 179.70 pg/mL (normal ); Phosphorylated tau: 15.51 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal and entorhinal cortex volumes are slightly reduced but still within the normal range (Z-scores -0.70 and -0.66, respectively). The MMSE score of 24 is borderline, and Aβ is moderately reduced, suggesting possible amyloid pathology, but tau markers are normal.  \n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to borderline MMSE and amyloid reduction, but no significant atrophy or tau elevation)",
  "timestamp": "2025-07-26T11:21:17.704554"
}