{
  "ptid_time": "023_S_1262_2007-09-04",
  "img_path": "/data/qiuhui/data/adni/images/023_S_1262/2007-09-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 40,494 mm³, 44.3% above the reference mean. With a Z-score of 1.01 (84.5th percentile), this represents mild enlargement; hippocampal volume measures 4,782 mm³, 32.8% below the reference mean. With a Z-score of -3.01 (0.1th percentile), this represents profound atrophy; whole brain volume measures 827,933 mm³, 15.1% below the reference mean. With a Z-score of -1.90 (2.9th percentile), this represents moderate atrophy; entorhinal cortex volume measures 1,994 mm³, 45.7% below the reference mean. With a Z-score of -2.81 (0.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,610 mm³, 31.8% below the reference mean. With a Z-score of -2.89 (0.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,411 mm³, 24.8% below the reference mean. With a Z-score of -2.15 (1.6th percentile), this represents significant atrophy. ",
  "text_data": "Age is 73.2 years. Gender is Female. Education: 12 years. MMSE: 15.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.01), significant atrophy in the entorhinal cortex (Z-score -2.81), fusiform gyrus (Z-score -2.89), and middle temporal gyrus (Z-score -2.15), along with moderate whole-brain atrophy (Z-score -1.90). These findings, combined with a low MMSE score of 15, strongly suggest neurodegenerative disease, likely Alzheimer's dementia, despite the absence of APOE4.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T02:57:42.196700"
}