{
  "ptid_time": "100_S_4512_2013-06-17",
  "img_path": "/data/qiuhui/data/adni/images/100_S_4512/2013-06-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 12,642 mm³, 43.4% below the reference mean. With a Z-score of -1.09 (13.9th percentile), this represents mild atrophy; hippocampal volume measures 6,571 mm³, 14.5% below the reference mean. With a Z-score of -1.63 (5.2th percentile), this represents moderate atrophy; whole brain volume measures 952,486 mm³, 7.5% below the reference mean. With a Z-score of -0.93 (17.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,315 mm³, 14.8% below the reference mean. With a Z-score of -1.15 (12.5th percentile), this represents mild atrophy; fusiform gyrus volume measures 19,103 mm³, 4.9% above the reference mean. With a Z-score of 0.55 (71.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,401 mm³, 5.5% below the reference mean. With a Z-score of -0.48 (31.4th percentile), this represents normal volume . ",
  "text_data": "Age is 69.0 years. Gender is Female. Education: 16 years. MMSE: 26.0. MoCA: 28.0. Logical Memory: 8.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging shows mild to moderate atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease, while other brain regions remain largely normal. Cognitive scores (MMSE 26, MoCA 28) are within normal limits, suggesting no significant functional impairment. The absence of APOE4 reduces genetic risk but does not rule out neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural atrophy is present, but cognitive performance is preserved, making early MCI more likely than dementia or normal aging.)",
  "timestamp": "2025-07-26T11:25:24.702983"
}