{
  "ptid_time": "023_S_0604_2006-06-20",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0604/2006-06-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 75,755 mm³, 61.1% above the reference mean. With a Z-score of 1.78 (96.2th percentile), this represents moderate enlargement; hippocampal volume measures 6,490 mm³, 6.9% below the reference mean. With a Z-score of -0.59 (27.7th percentile), this represents normal volume ; whole brain volume measures 1,068,720 mm³, 3.8% above the reference mean. With a Z-score of 0.50 (69.3th percentile), this represents normal volume ; entorhinal cortex volume measures 4,429 mm³, 11.6% above the reference mean. With a Z-score of 0.76 (77.6th percentile), this represents normal volume ; fusiform gyrus volume measures 17,311 mm³, 4.2% below the reference mean. With a Z-score of -0.36 (35.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,702 mm³, 2.3% below the reference mean. With a Z-score of -0.21 (41.7th percentile), this represents normal volume . ",
  "text_data": "Age is 86.5 years. Gender is Male. Education: 14 years. Handedness: Right. Race: White. Medical history: Psychiatric; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1079.00 pg/mL (normal ); Total tau: 309.10 pg/mL (normal ); Phosphorylated tau: 30.47 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The patient shows moderate ventricular enlargement, which is often associated with brain atrophy, but other key regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges. Biomarkers (Aβ normal, T-tau normal, P-tau mildly elevated) do not strongly support Alzheimer’s pathology. The MMSE score of 25 is borderline but not definitive for dementia.  \nDiagnosis: CN (Cognitively Normal)  \nConfidence: Medium",
  "timestamp": "2025-07-26T02:44:08.605384"
}