{
  "ptid_time": "027_S_1082_2007-06-04",
  "img_path": "/data/qiuhui/data/adni/images/027_S_1082/2007-06-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,592 mm³, 73.1% above the reference mean. With a Z-score of 1.67 (95.3th percentile), this represents moderate enlargement; hippocampal volume measures 4,401 mm³, 38.1% below the reference mean. With a Z-score of -3.50 (0.0th percentile), this represents profound atrophy; whole brain volume measures 864,534 mm³, 11.3% below the reference mean. With a Z-score of -1.42 (7.7th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,972 mm³, 46.3% below the reference mean. With a Z-score of -2.84 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,740 mm³, 31.0% below the reference mean. With a Z-score of -2.82 (0.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,956 mm³, 27.2% below the reference mean. With a Z-score of -2.36 (0.9th percentile), this represents significant atrophy. ",
  "text_data": "Age is 70.0 years. Gender is Female. Education: 13 years. MMSE: 20.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.50), significant entorhinal cortex and fusiform gyrus atrophy, and moderate ventricular enlargement—all hallmarks of Alzheimer's pathology. The MMSE score of 20 indicates cognitive impairment, and the presence of two APOE4 alleles further increases Alzheimer's risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T03:46:49.916054"
}