{
  "ptid_time": "023_S_0887_2007-03-29",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0887/2007-03-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 36,269 mm³, 29.2% above the reference mean. With a Z-score of 0.67 (74.8th percentile), this represents normal volume ; hippocampal volume measures 4,600 mm³, 35.3% below the reference mean. With a Z-score of -3.24 (0.1th percentile), this represents profound atrophy; whole brain volume measures 971,135 mm³, 0.4% below the reference mean. With a Z-score of -0.05 (48.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,466 mm³, 32.9% below the reference mean. With a Z-score of -2.02 (2.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 13,879 mm³, 18.4% below the reference mean. With a Z-score of -1.68 (4.7th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 19,700 mm³, 2.8% above the reference mean. With a Z-score of 0.24 (59.5th percentile), this represents normal volume . ",
  "text_data": "Age is 74.2 years. Gender is Female. Education: 8 years. MMSE: 21.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.24) and significant entorhinal cortex atrophy (Z-score -2.02), both strongly associated with Alzheimer's pathology. The MMSE score of 21 indicates cognitive impairment, consistent with the structural findings.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given the hippocampal and entorhinal atrophy).  \n\n**Confidence:** **High** (due to severe atrophy in key memory-related regions and corroborating cognitive decline).",
  "timestamp": "2025-07-26T02:47:47.239287"
}