{
  "ptid_time": "130_S_4660_2013-05-02",
  "img_path": "/data/qiuhui/data/adni/images/130_S_4660/2013-05-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,641 mm³, 19.3% below the reference mean. With a Z-score of -0.44 (32.9th percentile), this represents normal volume ; hippocampal volume measures 4,383 mm³, 38.4% below the reference mean. With a Z-score of -3.52 (0.0th percentile), this represents profound atrophy; whole brain volume measures 841,007 mm³, 13.7% below the reference mean. With a Z-score of -1.73 (4.2th percentile), this represents moderate atrophy; entorhinal cortex volume measures 1,751 mm³, 52.3% below the reference mean. With a Z-score of -3.21 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 16,381 mm³, 3.7% below the reference mean. With a Z-score of -0.34 (36.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 14,511 mm³, 24.3% below the reference mean. With a Z-score of -2.11 (1.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 78.2 years. Gender is Female. Education: 16 years. MMSE: 19.0. MoCA: 18.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, along with moderate whole-brain atrophy and significant middle temporal gyrus atrophy—all key regions affected in Alzheimer’s disease. The cognitive scores (MMSE 19, MoCA 18) are consistent with moderate cognitive impairment, and the presence of one APOE4 allele further supports Alzheimer’s pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T14:51:12.401120"
}