{
  "ptid_time": "003_S_6258_2018-03-13",
  "img_path": "/data/qiuhui/data/adni/images/003_S_6258/2018-03-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 70,526 mm³, 83.1% above the reference mean. With a Z-score of 1.99 (97.7th percentile), this represents moderate enlargement; hippocampal volume measures 6,869 mm³, 9.1% below the reference mean. With a Z-score of -0.89 (18.7th percentile), this represents normal volume ; whole brain volume measures 1,137,480 mm³, 5.4% above the reference mean. With a Z-score of 0.70 (75.8th percentile), this represents normal volume ; entorhinal cortex volume measures 3,702 mm³, 9.7% below the reference mean. With a Z-score of -0.66 (25.5th percentile), this represents normal volume ; fusiform gyrus volume measures 19,878 mm³, 5.5% above the reference mean. With a Z-score of 0.47 (68.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,157 mm³, 3.8% above the reference mean. With a Z-score of 0.34 (63.5th percentile), this represents normal volume . ",
  "text_data": "Age is 79.8 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. MMSE: 29.0. MoCA: 24.0. Logical Memory: 14.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.55 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular enlargement (suggesting possible atrophy) but otherwise normal hippocampal, whole brain, and regional cortical volumes. Cognitive scores are mixed (MMSE 29 is normal, MoCA 24 suggests mild impairment), and the presence of APOE4 and elevated AV45 (amyloid PET) indicates significant Alzheimer's pathology.  \n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology given amyloid positivity).  \n**Confidence:** **Medium** (volumetric findings are not strongly supportive of dementia, but amyloid burden and MoCA score suggest early cognitive decline).  \n\n*Note: A clinical correlation with functional decline is needed for a definitive diagnosis of MCI vs. early dementia.*",
  "timestamp": "2025-07-25T21:00:03.657581"
}