{
  "ptid_time": "052_S_0952_2011-11-08",
  "img_path": "/data/qiuhui/data/adni/images/052_S_0952/2011-11-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 58,224 mm³, 57.5% above the reference mean. With a Z-score of 1.55 (94.0th percentile), this represents moderate enlargement; hippocampal volume measures 4,661 mm³, 28.2% below the reference mean. With a Z-score of -2.26 (1.2th percentile), this represents significant atrophy; whole brain volume measures 763,230 mm³, 17.8% below the reference mean. With a Z-score of -2.13 (1.6th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,720 mm³, 50.3% below the reference mean. With a Z-score of -2.72 (0.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 9,726 mm³, 39.6% below the reference mean. With a Z-score of -2.98 (0.1th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,478 mm³, 19.7% below the reference mean. With a Z-score of -1.75 (4.0th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 86.7 years. Gender is Female. Education: 13 years. MMSE: 19.0. MoCA: 10.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus) alongside moderate-to-severe whole-brain atrophy. The cognitive scores (MMSE 19, MoCA 10) are well below normal thresholds for age, and the presence of an APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T07:41:55.299363"
}