{
  "ptid_time": "094_S_1015_2006-10-30",
  "img_path": "/data/qiuhui/data/adni/images/094_S_1015/2006-10-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 55,108 mm³, 120.4% above the reference mean. With a Z-score of 1.60 (94.5th percentile), this represents moderate enlargement; hippocampal volume measures 6,780 mm³.; whole brain volume measures 1,144,840 mm³, 4.0% below the reference mean. With a Z-score of -0.73 (23.2th percentile), this represents normal volume ; entorhinal cortex volume measures 3,648 mm³, 8.9% below the reference mean. With a Z-score of -0.78 (21.8th percentile), this represents normal volume ; fusiform gyrus volume measures 15,279 mm³, 26.7% below the reference mean. With a Z-score of -4.06 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 14,633 mm³.. ",
  "text_data": "Age is 58.7 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Psychiatric; Cardiovascular; Musculoskeletal; Allergies or Drug Sensitivities; Smoking. MMSE: 26.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in the fusiform gyrus (profound atrophy, Z-score -4.06) and moderate ventricular enlargement (Z-score 1.60), which are concerning for neurodegenerative changes. The MMSE score of 26 is borderline, and the absence of APOE4 reduces but does not eliminate Alzheimer's risk. Hippocampal and whole brain volumes are within normal limits, but the fusiform gyrus atrophy is highly suggestive of pathology.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting markers—fusiform atrophy is severe, but other structures are relatively preserved, and MMSE is only mildly impaired).",
  "timestamp": "2025-07-26T10:14:35.354123"
}