{
  "ptid_time": "029_S_1073_2008-05-02",
  "img_path": "/data/qiuhui/data/adni/images/029_S_1073/2008-05-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,563 mm³, 1.0% above the reference mean. With a Z-score of 0.03 (51.0th percentile), this represents normal volume ; hippocampal volume measures 5,609 mm³, 27.0% below the reference mean. With a Z-score of -3.03 (0.1th percentile), this represents profound atrophy; whole brain volume measures 905,623 mm³, 12.0% below the reference mean. With a Z-score of -1.49 (6.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,478 mm³, 36.3% below the reference mean. With a Z-score of -2.82 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,612 mm³, 19.8% below the reference mean. With a Z-score of -2.22 (1.3th percentile), this represents significant atrophy; middle temporal gyrus volume measures 16,904 mm³, 17.6% below the reference mean. With a Z-score of -1.57 (5.9th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 67.2 years. Gender is Female. Education: 18 years. MMSE: 25.0. Laboratory findings: Neutrophils: 6.15 (significant elevated). APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus and significant atrophy in the entorhinal cortex and fusiform gyrus, which are key regions affected in Alzheimer's disease. The MMSE score of 25 is borderline, but the structural changes strongly suggest neurodegeneration. The presence of one APOE4 allele further increases the risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T04:21:58.217597"
}