{
  "ptid_time": "022_S_0129_2006-08-11",
  "img_path": "/data/qiuhui/data/adni/images/022_S_0129/2006-08-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 42,484 mm³, 14.9% above the reference mean. With a Z-score of 0.40 (65.7th percentile), this represents normal volume ; hippocampal volume measures 4,263 mm³, 34.4% below the reference mean. With a Z-score of -2.75 (0.3th percentile), this represents significant atrophy; whole brain volume measures 830,858 mm³, 10.5% below the reference mean. With a Z-score of -1.26 (10.4th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,181 mm³, 37.0% below the reference mean. With a Z-score of -2.00 (2.3th percentile), this represents moderate atrophy; fusiform gyrus volume measures 12,501 mm³, 22.4% below the reference mean. With a Z-score of -1.68 (4.6th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 14,523 mm³, 19.4% below the reference mean. With a Z-score of -1.73 (4.2th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 80.7 years. Gender is Female. Education: 16 years. MMSE: 23.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits significant hippocampal atrophy (Z-score -2.75, 0.3th percentile) and moderate atrophy in the entorhinal cortex, fusiform gyrus, and middle temporal gyrus, all of which are key regions affected in Alzheimer's disease. The MMSE score of 23 suggests mild cognitive impairment, and the absence of APOE4 does not rule out AD, as neurodegeneration patterns are strongly indicative.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T02:01:25.795356"
}