{
  "ptid_time": "005_S_0448_2008-06-03",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0448/2008-06-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 75,484 mm³, 60.5% above the reference mean. With a Z-score of 1.76 (96.1th percentile), this represents moderate enlargement; hippocampal volume measures 6,042 mm³, 13.3% below the reference mean. With a Z-score of -1.15 (12.5th percentile), this represents mild atrophy; whole brain volume measures 1,057,440 mm³, 2.7% above the reference mean. With a Z-score of 0.36 (64.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,430 mm³, 13.6% below the reference mean. With a Z-score of -0.89 (18.7th percentile), this represents normal volume ; fusiform gyrus volume measures 15,964 mm³, 11.6% below the reference mean. With a Z-score of -1.01 (15.7th percentile), this represents mild atrophy; middle temporal gyrus volume measures 18,074 mm³, 10.4% below the reference mean. With a Z-score of -0.93 (17.6th percentile), this represents normal volume . ",
  "text_data": "Age is 87.5 years. Gender is Male. Education: 17 years. MMSE: 30.0. Logical Memory: 6.0. Laboratory findings: Eosinophils: 0.48 (profound elevated); Eosinophils: 6.70 (significant elevated); Total Bilirubin: 0.80 (significant elevated); AST (SGOT): 13.00 (significant reduced). APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1503.00 pg/mL (mild elevated); Total tau: 226.20 pg/mL (normal ); Phosphorylated tau: 20.69 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows moderate ventricular enlargement and mild hippocampal atrophy, which are structural changes often associated with neurodegenerative processes. However, the MMSE score of 30 is intact, and CSF biomarkers (Aβ mildly elevated, normal T-tau and P-tau) do not strongly support active Alzheimer’s pathology.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (Structural changes raise concern, but cognitive and biomarker profiles do not yet meet criteria for MCI or dementia.)",
  "timestamp": "2025-07-25T21:07:34.917048"
}