{
  "ptid_time": "941_S_1311_2007-03-02",
  "img_path": "/data/qiuhui/data/adni/images/941_S_1311/2007-03-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 101,096 mm³, 236.7% above the reference mean. With a Z-score of 5.62 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,899 mm³, 14.1% below the reference mean. With a Z-score of -1.40 (8.0th percentile), this represents mild atrophy; whole brain volume measures 970,229 mm³, 14.5% below the reference mean. With a Z-score of -2.05 (2.0th percentile), this represents significant atrophy; entorhinal cortex volume measures 3,628 mm³, 14.9% below the reference mean. With a Z-score of -1.03 (15.1th percentile), this represents mild atrophy; fusiform gyrus volume measures 18,382 mm³, 7.7% below the reference mean. With a Z-score of -0.64 (26.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 15,716 mm³, 29.9% below the reference mean. With a Z-score of -2.46 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 69.1 years. Gender is Male. Education: 12 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Hematopoietic-Lymphatic; Renal-Genitourinary; Alcohol Abuse; Smoking; Major Surgical Procedures. MMSE: 29.0. Logical Memory: 4.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 5.62) and significant atrophy in whole brain (Z-score -2.05) and middle temporal gyrus (Z-score -2.46), alongside mild hippocampal and entorhinal cortex atrophy. Despite these structural changes, the MMSE score of 29 is within the normal range, suggesting preserved cognitive function. The presence of two APOE4 alleles increases Alzheimer's risk but does not confirm impairment.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (due to conflicting evidence—severe atrophy but normal MMSE; APOE4 status suggests future risk but not current impairment).",
  "timestamp": "2025-07-26T17:31:01.384102"
}