{
  "ptid_time": "011_S_4845_2013-07-08",
  "img_path": "/data/qiuhui/data/adni/images/011_S_4845/2013-07-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 57,763 mm³, 158.6% above the reference mean. With a Z-score of 3.97 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,221 mm³, 45.1% below the reference mean. With a Z-score of -5.06 (0.0th percentile), this represents profound atrophy; whole brain volume measures 860,034 mm³, 16.4% below the reference mean. With a Z-score of -2.05 (2.0th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,389 mm³, 38.6% below the reference mean. With a Z-score of -2.99 (0.1th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,127 mm³, 22.4% below the reference mean. With a Z-score of -2.52 (0.6th percentile), this represents significant atrophy; middle temporal gyrus volume measures 11,955 mm³, 41.7% below the reference mean. With a Z-score of -3.71 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 69.0 years. Gender is Female. Education: 20 years. MMSE: 16.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -5.06) and significant atrophy in other key Alzheimer’s-related regions (entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside severe ventricular enlargement. The MMSE score of 16 indicates severe cognitive impairment, and the presence of one APOE4 allele increases Alzheimer’s risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T23:00:27.147182"
}