{
  "ptid_time": "123_S_0113_2012-03-08",
  "img_path": "/data/qiuhui/data/adni/images/123_S_0113/2012-03-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 136,102 mm³, 189.5% above the reference mean. With a Z-score of 5.50 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,069 mm³, 12.9% below the reference mean. With a Z-score of -1.11 (13.2th percentile), this represents mild atrophy; whole brain volume measures 1,079,950 mm³, 4.9% above the reference mean. With a Z-score of 0.65 (74.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,258 mm³, 17.9% below the reference mean. With a Z-score of -1.17 (12.0th percentile), this represents mild atrophy; fusiform gyrus volume measures 20,301 mm³, 12.4% above the reference mean. With a Z-score of 1.07 (85.8th percentile), this represents mild enlargement; middle temporal gyrus volume measures 19,694 mm³, 2.4% below the reference mean. With a Z-score of -0.21 (41.6th percentile), this represents normal volume . ",
  "text_data": "Age is 81.2 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. MMSE: 28.0. MoCA: 24.0. Logical Memory: 15.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 5.50) and mild atrophy in the hippocampus (Z-score -1.11) and entorhinal cortex (Z-score -1.17), which are key regions affected in Alzheimer's disease. However, cognitive scores (MMSE 28, MoCA 24) are only mildly impaired, suggesting preserved function despite structural changes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural changes are concerning, but cognitive performance is borderline normal/MCI, and APOE4-negative status reduces certainty of progression to dementia.)",
  "timestamp": "2025-07-26T12:26:05.600107"
}