{
  "ptid_time": "116_S_1271_2007-09-05",
  "img_path": "/data/qiuhui/data/adni/images/116_S_1271/2007-09-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 84,153 mm³, 118.5% above the reference mean. With a Z-score of 2.84 (99.8th percentile), this represents significant enlargement; hippocampal volume measures 5,924 mm³, 21.6% below the reference mean. With a Z-score of -2.11 (1.7th percentile), this represents significant atrophy; whole brain volume measures 876,083 mm³, 18.8% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,971 mm³, 27.5% below the reference mean. With a Z-score of -1.87 (3.1th percentile), this represents moderate atrophy; fusiform gyrus volume measures 14,779 mm³, 21.5% below the reference mean. With a Z-score of -1.84 (3.3th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,517 mm³, 27.3% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 71.7 years. Gender is Male. Education: 16 years. MMSE: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in multiple brain regions critical for memory and cognition (hippocampus, whole brain, middle temporal gyrus) alongside ventricular enlargement, which is consistent with neurodegenerative changes. The MMSE score of 23 indicates mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given the hippocampal and temporal lobe atrophy).  \n\n**Confidence:** **High** (due to clear structural atrophy, low MMSE, and APOE4 status).",
  "timestamp": "2025-07-26T12:04:05.193072"
}