{
  "ptid_time": "041_S_6226_2018-03-29",
  "img_path": "/data/qiuhui/data/adni/images/041_S_6226/2018-03-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,668 mm³, 34.3% below the reference mean. With a Z-score of -0.86 (19.5th percentile), this represents normal volume ; hippocampal volume measures 8,348 mm³, 8.6% above the reference mean. With a Z-score of 0.97 (83.4th percentile), this represents normal volume ; whole brain volume measures 1,129,130 mm³, 9.7% above the reference mean. With a Z-score of 1.21 (88.7th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,247 mm³, 16.6% below the reference mean. With a Z-score of -1.29 (9.9th percentile), this represents mild atrophy; fusiform gyrus volume measures 19,406 mm³, 6.6% above the reference mean. With a Z-score of 0.74 (77.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,007 mm³, 17.0% above the reference mean. With a Z-score of 1.51 (93.5th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 65.4 years. Gender is Female. Education: 18 years. MMSE: 30.0. MoCA: 30.0. Logical Memory: 15.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.08 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows normal hippocampal and whole brain volumes, with mild entorhinal cortex atrophy but no significant atrophy in other Alzheimer’s-related regions. Cognitive scores (MMSE, MoCA) are intact, and amyloid PET (AV45) is normal. The presence of one APOE4 allele increases genetic risk but does not confirm pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mild entorhinal atrophy, but normal cognition and amyloid status suggest no active disease)",
  "timestamp": "2025-07-26T07:29:18.419579"
}