{
  "ptid_time": "018_S_0087_2006-08-21",
  "img_path": "/data/qiuhui/data/adni/images/018_S_0087/2006-08-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 67,877 mm³, 76.2% above the reference mean. With a Z-score of 1.83 (96.6th percentile), this represents moderate enlargement; hippocampal volume measures 5,658 mm³, 25.2% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy; whole brain volume measures 1,149,390 mm³, 6.5% above the reference mean. With a Z-score of 0.84 (80.0th percentile), this represents normal volume ; entorhinal cortex volume measures 1,794 mm³, 56.3% below the reference mean. With a Z-score of -3.81 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 16,426 mm³, 12.8% below the reference mean. With a Z-score of -1.09 (13.8th percentile), this represents mild atrophy; middle temporal gyrus volume measures 21,145 mm³, 0.9% below the reference mean. With a Z-score of -0.08 (46.7th percentile), this represents normal volume . ",
  "text_data": "Age is 75.6 years. Gender is Male. Education: 14 years. MMSE: 26.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant hippocampal atrophy (Z-score -2.45, 0.7th percentile) and profound entorhinal cortex atrophy (Z-score -3.81, 0.0th percentile), both hallmark features of Alzheimer’s disease. Despite a normal MMSE score (26/30), the structural changes are strongly suggestive of neurodegeneration.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High** (due to severe atrophy in key AD-vulnerable regions despite borderline-normal MMSE)",
  "timestamp": "2025-07-26T00:43:29.082542"
}