{
  "ptid_time": "126_S_2407_2012-11-26",
  "img_path": "/data/qiuhui/data/adni/images/126_S_2407/2012-11-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 18,356 mm³, 17.8% below the reference mean. With a Z-score of -0.45 (32.8th percentile), this represents normal volume ; hippocampal volume measures 3,601 mm³, 53.1% below the reference mean. With a Z-score of -5.96 (0.0th percentile), this represents profound atrophy; whole brain volume measures 903,834 mm³, 12.2% below the reference mean. With a Z-score of -1.52 (6.5th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 69.0 years. Gender is Female. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Endocrine-Metabolic; Renal-Genitourinary; Smoking; Major Surgical Procedures. MMSE: 28.0. MoCA: 25.0. Logical Memory: 9.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows profound atrophy (Z-score -5.96, 0th percentile), which is strongly associated with Alzheimer's pathology, while whole brain volume shows moderate atrophy. However, cognitive scores (MMSE 28, MoCA 25) are near-normal, suggesting preserved function despite structural changes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (due to significant hippocampal atrophy with relatively intact cognition).  \n\n**Confidence:** **Medium** (cognitive scores are borderline, and APOE4-negative status reduces certainty of progression to dementia).",
  "timestamp": "2025-07-26T12:44:52.866042"
}