{
  "ptid_time": "941_S_6333_2020-09-01",
  "img_path": "/data/qiuhui/data/adni/images/941_S_6333/2020-09-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 78,920 mm³, 67.9% above the reference mean. With a Z-score of 1.97 (97.6th percentile), this represents moderate enlargement; hippocampal volume measures 7,134 mm³, 2.4% above the reference mean. With a Z-score of 0.21 (58.2th percentile), this represents normal volume ; whole brain volume measures 1,196,830 mm³, 16.3% above the reference mean. With a Z-score of 2.13 (98.4th percentile), this represents significant enlargement; entorhinal cortex volume measures 4,342 mm³, 9.4% above the reference mean. With a Z-score of 0.62 (73.1th percentile), this represents normal volume ; fusiform gyrus volume measures 20,737 mm³, 14.8% above the reference mean. With a Z-score of 1.28 (90.0th percentile), this represents mild enlargement; middle temporal gyrus volume measures 22,619 mm³, 12.1% above the reference mean. With a Z-score of 1.09 (86.2th percentile), this represents mild enlargement. ",
  "text_data": "Age is 80.4 years. Gender is Male. Education: 16 years. MMSE: 28.0. MoCA: 19.0. Logical Memory: 11.0. APOEε4 alleles: 1.0. Biomarker levels: Flobetaben (FBB): 1.56 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is moderately enlarged (Z-score 1.97), which can indicate atrophy, but hippocampal and entorhinal cortex volumes are normal. The MoCA score (19/30) suggests cognitive impairment, while the MMSE (28/30) is borderline normal, indicating possible mild cognitive deficits. The presence of one APOE4 allele increases Alzheimer's risk but does not confirm dementia alone.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Discrepancy between MMSE and MoCA, normal hippocampal volume, but ventricular enlargement and APOE4 suggest early neurodegenerative changes.)",
  "timestamp": "2025-07-26T17:46:58.255521"
}