{
  "ptid_time": "068_S_4217_2011-09-06",
  "img_path": "/data/qiuhui/data/adni/images/068_S_4217/2011-09-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,171 mm³, 6.9% above the reference mean. With a Z-score of 0.17 (56.6th percentile), this represents normal volume ; hippocampal volume measures 7,682 mm³, 1.6% above the reference mean. With a Z-score of 0.16 (56.3th percentile), this represents normal volume ; whole brain volume measures 1,061,580 mm³, 1.7% below the reference mean. With a Z-score of -0.21 (41.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,868 mm³, 5.7% below the reference mean. With a Z-score of -0.38 (35.0th percentile), this represents normal volume ; fusiform gyrus volume measures 18,879 mm³, 0.2% above the reference mean. With a Z-score of 0.02 (50.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,633 mm³, 1.4% above the reference mean. With a Z-score of 0.12 (54.9th percentile), this represents normal volume . ",
  "text_data": "Age is 76.4 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 30.0. MoCA: 24.0. Logical Memory: 9.0. Laboratory findings: . APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.91 SUVR (mild reduced); Amyloid beta: 1684.00 pg/mL (moderate elevated); Total tau: 186.20 pg/mL (normal ); Phosphorylated tau: 17.43 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volume measurements (ventricular, hippocampal, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) are all within normal ranges, with no significant atrophy. The MMSE score of 30 is normal, but the MoCA score of 24 suggests mild cognitive impairment (MCI). Biomarkers show moderately elevated Aβ (amyloid) but normal tau levels, which may indicate early amyloid accumulation without significant neurodegeneration.  \n\nDiagnosis: **MCI**  \nConfidence: **Medium** (due to the discrepancy between MMSE and MoCA, along with elevated Aβ but normal tau and brain volumes)",
  "timestamp": "2025-07-26T09:00:19.307199"
}