{
  "ptid_time": "094_S_0526_2008-05-22",
  "img_path": "/data/qiuhui/data/adni/images/094_S_0526/2008-05-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,759 mm³, 41.1% below the reference mean. With a Z-score of -1.11 (13.3th percentile), this represents mild atrophy; hippocampal volume measures 6,183 mm³, 4.8% below the reference mean. With a Z-score of -0.38 (35.0th percentile), this represents normal volume ; whole brain volume measures 819,684 mm³, 11.7% below the reference mean. With a Z-score of -1.40 (8.0th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,080 mm³, 11.1% below the reference mean. With a Z-score of -0.60 (27.5th percentile), this represents normal volume ; fusiform gyrus volume measures 11,975 mm³, 25.7% below the reference mean. With a Z-score of -1.93 (2.7th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,163 mm³, 15.9% below the reference mean. With a Z-score of -1.41 (7.9th percentile), this represents mild atrophy. ",
  "text_data": "Age is 87.1 years. Gender is Female. Education: 7 years. MMSE: 27.0. Logical Memory: 5.0. Laboratory findings: Calcium (EDTA): 11.40 (profound elevated); Triglycerides (GPO): 290.00 (profound elevated). APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows mild to moderate atrophy in several brain regions (ventricular volume, whole brain, fusiform gyrus, middle temporal gyrus), while hippocampal and entorhinal cortex volumes remain within normal ranges. The MMSE score of 27 is within the normal range for age, and the absence of APOE4 reduces genetic risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Atrophy patterns suggest early neurodegeneration, but preserved cognitive function and lack of APOE4 make dementia less likely at this stage.)",
  "timestamp": "2025-07-26T10:12:10.772700"
}