{
  "ptid_time": "012_S_6760_2019-06-26",
  "img_path": "/data/qiuhui/data/adni/images/012_S_6760/2019-06-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 77,008 mm³, 99.9% above the reference mean. With a Z-score of 2.39 (99.2th percentile), this represents significant enlargement; hippocampal volume measures 5,906 mm³, 21.9% below the reference mean. With a Z-score of -2.13 (1.6th percentile), this represents significant atrophy; whole brain volume measures 1,045,510 mm³, 3.1% below the reference mean. With a Z-score of -0.41 (34.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,793 mm³, 31.9% below the reference mean. With a Z-score of -2.16 (1.5th percentile), this represents significant atrophy; fusiform gyrus volume measures 19,736 mm³, 4.8% above the reference mean. With a Z-score of 0.41 (65.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,835 mm³, 7.0% above the reference mean. With a Z-score of 0.63 (73.6th percentile), this represents normal volume . ",
  "text_data": "Age is 70.8 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. MMSE: 26.0. MoCA: 21.0. Logical Memory: 10.0. Biomarker levels: Florbetapir (AV45): 0.86 SUVR (moderate reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD). Ventricular enlargement further supports neurodegeneration. The MMSE (26) and MoCA (21) scores indicate mild cognitive impairment, and the moderate reduction in AV45 (amyloid PET) suggests amyloid pathology.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI) due to Alzheimer’s disease** (likely prodromal AD given amyloid positivity and neurodegeneration).  \n\n**Confidence:** **High** (due to clear structural atrophy in AD-vulnerable regions, amyloid positivity, and cognitive scores consistent with MCI).",
  "timestamp": "2025-07-25T23:19:37.131931"
}