{
  "ptid_time": "127_S_4645_2012-04-04",
  "img_path": "/data/qiuhui/data/adni/images/127_S_4645/2012-04-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 39,526 mm³, 40.8% above the reference mean. With a Z-score of 0.93 (82.5th percentile), this represents normal volume ; hippocampal volume measures 7,834 mm³, 10.1% above the reference mean. With a Z-score of 0.93 (82.3th percentile), this represents normal volume ; whole brain volume measures 1,059,410 mm³, 8.7% above the reference mean. With a Z-score of 1.09 (86.3th percentile), this represents mild enlargement; entorhinal cortex volume measures 4,067 mm³, 10.7% above the reference mean. With a Z-score of 0.66 (74.5th percentile), this represents normal volume ; fusiform gyrus volume measures 18,130 mm³, 6.6% above the reference mean. With a Z-score of 0.60 (72.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,712 mm³, 13.3% above the reference mean. With a Z-score of 1.15 (87.5th percentile), this represents mild enlargement. ",
  "text_data": "Age is 76.3 years. Gender is Female. Education: 14 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 30.0. MoCA: 26.0. Logical Memory: 14.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.21 SUVR (normal ); Amyloid beta: 539.10 pg/mL (mild reduced); Total tau: 206.50 pg/mL (normal ); Phosphorylated tau: 21.56 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volumes (hippocampus, entorhinal cortex, fusiform gyrus, etc.) are all within normal or mildly enlarged ranges, with no significant atrophy. Cognitive scores (MMSE 30, MoCA 26) are within normal limits, and biomarkers (Aβ mildly reduced, normal tau and AV45) do not strongly support Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mildly reduced Aβ, but no other supporting evidence for MCI/dementia)",
  "timestamp": "2025-07-26T13:20:30.612242"
}