{
  "ptid_time": "052_S_4885_2016-09-12",
  "img_path": "/data/qiuhui/data/adni/images/052_S_4885/2016-09-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 43,907 mm³, 14.0% above the reference mean. With a Z-score of 0.34 (63.1th percentile), this represents normal volume ; hippocampal volume measures 4,988 mm³, 34.0% below the reference mean. With a Z-score of -3.32 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,007,130 mm³, 6.7% below the reference mean. With a Z-score of -0.87 (19.2th percentile), this represents normal volume ; entorhinal cortex volume measures 1,902 mm³, 53.6% below the reference mean. With a Z-score of -3.64 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 15,511 mm³, 17.7% below the reference mean. With a Z-score of -1.50 (6.6th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,964 mm³, 25.2% below the reference mean. With a Z-score of -2.26 (1.2th percentile), this represents significant atrophy. ",
  "text_data": "Age is 79.0 years. Gender is Male. Education: 20 years. MMSE: 21.0. MoCA: 19.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.60 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, along with significant atrophy in the middle temporal gyrus—key regions affected in Alzheimer's disease. The cognitive scores (MMSE 21, MoCA 19) are below normal for age, and the presence of APOE4 and elevated AV45 (amyloid PET) strongly support Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T07:51:05.102967"
}