{
  "ptid_time": "036_S_0760_2006-08-25",
  "img_path": "/data/qiuhui/data/adni/images/036_S_0760/2006-08-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,926 mm³, 87.7% above the reference mean. With a Z-score of 2.19 (98.6th percentile), this represents significant enlargement; hippocampal volume measures 5,478 mm³, 28.7% below the reference mean. With a Z-score of -3.22 (0.1th percentile), this represents profound atrophy; whole brain volume measures 932,778 mm³, 9.4% below the reference mean. With a Z-score of -1.17 (12.2th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,458 mm³, 36.9% below the reference mean. With a Z-score of -2.86 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,476 mm³, 20.5% below the reference mean. With a Z-score of -2.31 (1.0th percentile), this represents significant atrophy; middle temporal gyrus volume measures 18,429 mm³, 10.2% below the reference mean. With a Z-score of -0.91 (18.3th percentile), this represents normal volume . ",
  "text_data": "Age is 69.4 years. Gender is Female. Education: 12 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Respiratory; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal and entorhinal cortex atrophy (Z-scores -3.22 and -2.86, respectively), which are hallmark features of Alzheimer's disease. The MMSE score of 25 suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T06:05:01.781077"
}