{
  "ptid_time": "053_S_1044_2007-11-21",
  "img_path": "/data/qiuhui/data/adni/images/053_S_1044/2007-11-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,769 mm³, 65.8% above the reference mean. With a Z-score of 1.56 (94.1th percentile), this represents moderate enlargement; hippocampal volume measures 5,994 mm³, 25.3% below the reference mean. With a Z-score of -2.53 (0.6th percentile), this represents significant atrophy; whole brain volume measures 997,122 mm³, 12.1% below the reference mean. With a Z-score of -1.71 (4.3th percentile), this represents moderate atrophy; entorhinal cortex volume measures 3,258 mm³, 23.6% below the reference mean. With a Z-score of -1.63 (5.1th percentile), this represents moderate atrophy; fusiform gyrus volume measures 16,711 mm³, 16.1% below the reference mean. With a Z-score of -1.34 (9.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,778 mm³, 25.1% below the reference mean. With a Z-score of -2.07 (1.9th percentile), this represents significant atrophy. ",
  "text_data": "Age is 66.6 years. Gender is Male. Education: 13 years. MMSE: 20.0. Logical Memory: 1.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal atrophy (Z-score -2.53, 0.6th percentile) and moderate-to-severe atrophy in other key regions (entorhinal cortex, middle temporal gyrus), alongside ventricular enlargement, consistent with neurodegenerative changes. The MMSE score of 20 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T07:57:06.346736"
}