{
  "ptid_time": "136_S_0426_2006-12-01",
  "img_path": "/data/qiuhui/data/adni/images/136_S_0426/2006-12-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 150,432 mm³, 220.0% above the reference mean. With a Z-score of 6.39 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 7,466 mm³, 7.1% above the reference mean. With a Z-score of 0.62 (73.2th percentile), this represents normal volume ; whole brain volume measures 1,279,170 mm³, 24.3% above the reference mean. With a Z-score of 3.18 (99.9th percentile), this represents profound enlargement; entorhinal cortex volume measures 2,901 mm³, 26.9% below the reference mean. With a Z-score of -1.76 (3.9th percentile), this represents moderate atrophy; fusiform gyrus volume measures 17,317 mm³, 4.1% below the reference mean. With a Z-score of -0.36 (36.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 23,046 mm³, 14.2% above the reference mean. With a Z-score of 1.28 (89.9th percentile), this represents mild enlargement. ",
  "text_data": "Age is 80.1 years. Gender is Male. Education: 16 years. MMSE: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 6.39) and entorhinal cortex atrophy (Z-score -1.76), which are strong indicators of neurodegeneration. The MMSE score of 23 suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely prodromal Alzheimer’s given entorhinal atrophy and APOE4 status).  \n\n**Confidence:** **Medium** (clinical correlation needed to rule out other causes of ventricular enlargement, such as normal pressure hydrocephalus).",
  "timestamp": "2025-07-26T16:01:19.833826"
}