{
  "ptid_time": "127_S_2213_2014-12-12",
  "img_path": "/data/qiuhui/data/adni/images/127_S_2213/2014-12-12/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 4,745 mm³, 26.9% below the reference mean. With a Z-score of -2.16 (1.5th percentile), this represents significant atrophy; whole brain volume measures 694,742 mm³, 25.2% below the reference mean. With a Z-score of -3.02 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 86.3 years. Gender is Female. Education: 14 years. MMSE: 28.0. MoCA: 22.0. Logical Memory: 5.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.53 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits significant hippocampal and profound whole-brain atrophy, with hippocampal volume at the 1.5th percentile and whole-brain volume at the 0.1th percentile. Despite a high MMSE score (28), the MoCA score (22) suggests mild cognitive impairment, and the absence of APOE4 does not rule out neurodegeneration given the profound amyloid burden (AV45 elevated).  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely prodromal Alzheimer’s given atrophy + amyloid positivity)  \n**Confidence:** **Medium** (high confidence in neurodegeneration, but MCI diagnosis is provisional due to near-normal MMSE; clinical correlation needed for dementia confirmation).",
  "timestamp": "2025-07-26T13:11:50.234379"
}