{
  "ptid_time": "016_S_1121_2007-12-14",
  "img_path": "/data/qiuhui/data/adni/images/016_S_1121/2007-12-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 34,262 mm³, 84.0% above the reference mean. With a Z-score of 2.40 (99.2th percentile), this represents significant enlargement; hippocampal volume measures 6,871 mm³, 12.0% below the reference mean. With a Z-score of -1.67 (4.8th percentile), this represents moderate atrophy; whole brain volume measures 1,090,400 mm³, 4.8% above the reference mean. With a Z-score of 0.57 (71.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,291 mm³, 10.9% below the reference mean. With a Z-score of -0.86 (19.6th percentile), this represents normal volume ; fusiform gyrus volume measures 19,309 mm³, 4.8% above the reference mean. With a Z-score of 0.43 (66.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,061 mm³, 7.2% below the reference mean. With a Z-score of -0.59 (27.7th percentile), this represents normal volume . ",
  "text_data": "Age is 57.2 years. Gender is Female. Education: 18 years. MMSE: 22.0. Logical Memory: 2.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 2.40) and moderate hippocampal atrophy (Z-score -1.67), both of which are strong indicators of neurodegeneration. The MMSE score of 22 suggests cognitive impairment, but the absence of APOE4 and relatively preserved whole brain and other regional volumes suggest a less aggressive progression.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to the presence of structural changes and cognitive decline, but lack of severe global atrophy or APOE4 risk factor)",
  "timestamp": "2025-07-26T00:14:27.687715"
}