{
  "ptid_time": "002_S_4237_2012-11-01",
  "img_path": "/data/qiuhui/data/adni/images/002_S_4237/2012-11-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 99,575 mm³, 169.4% above the reference mean. With a Z-score of 4.57 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,390 mm³, 1.6% below the reference mean. With a Z-score of -0.13 (44.8th percentile), this represents normal volume ; whole brain volume measures 972,502 mm³, 4.8% above the reference mean. With a Z-score of 0.57 (71.7th percentile), this represents normal volume . ",
  "text_data": "Age is 81.9 years. Gender is Female. Education: 13 years. MMSE: 27.0. MoCA: 19.0. Logical Memory: 6.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 4.57), which is strongly associated with neurodegeneration, while hippocampal volume is normal (Z-score -0.13). The MMSE (27) is borderline normal, but the MoCA (19) suggests cognitive impairment, particularly in executive function or attention. The absence of APOE4 reduces genetic risk but does not rule out dementia.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely transitioning to dementia given ventricular enlargement and MoCA score).  \n\n**Confidence:** **Medium** (ventricular enlargement is severe, but hippocampal preservation and MMSE score introduce some uncertainty).",
  "timestamp": "2025-07-25T20:24:54.204898"
}