{
  "ptid_time": "011_S_0023_2006-05-10",
  "img_path": "/data/qiuhui/data/adni/images/011_S_0023/2006-05-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,663 mm³, 41.2% below the reference mean. With a Z-score of -0.99 (16.2th percentile), this represents normal volume ; hippocampal volume measures 8,314 mm³, 10.0% above the reference mean. With a Z-score of 0.97 (83.5th percentile), this represents normal volume ; whole brain volume measures 1,030,820 mm³, 4.5% below the reference mean. With a Z-score of -0.58 (28.0th percentile), this represents normal volume ; entorhinal cortex volume measures 3,319 mm³, 19.1% below the reference mean. With a Z-score of -1.29 (9.8th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,293 mm³, 8.2% below the reference mean. With a Z-score of -0.70 (24.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,259 mm³, 9.7% below the reference mean. With a Z-score of -0.88 (19.0th percentile), this represents normal volume . ",
  "text_data": "Age is 72.2 years. Gender is Male. Education: 14 years. MMSE: 28.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows mild atrophy in the entorhinal cortex (Z-score -1.29, 9.8th percentile), while other regions (hippocampus, whole brain, fusiform gyrus, middle temporal gyrus) are within normal ranges. The MMSE score of 28 is normal, and the absence of APOE4 reduces genetic risk. Mild entorhinal atrophy could suggest early neurodegeneration but is insufficient for MCI or dementia diagnosis without cognitive deficits.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to isolated entorhinal atrophy but normal cognition and other volumes)",
  "timestamp": "2025-07-25T22:41:34.789090"
}