{
  "ptid_time": "024_S_1063_2007-11-12",
  "img_path": "/data/qiuhui/data/adni/images/024_S_1063/2007-11-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 39,333 mm³, 40.1% above the reference mean. With a Z-score of 0.92 (82.1th percentile), this represents normal volume ; hippocampal volume measures 6,299 mm³, 11.5% below the reference mean. With a Z-score of -1.05 (14.7th percentile), this represents mild atrophy; whole brain volume measures 932,718 mm³, 4.3% below the reference mean. With a Z-score of -0.54 (29.4th percentile), this represents normal volume ; entorhinal cortex volume measures 2,997 mm³, 18.4% below the reference mean. With a Z-score of -1.13 (12.9th percentile), this represents mild atrophy; fusiform gyrus volume measures 14,152 mm³, 16.8% below the reference mean. With a Z-score of -1.53 (6.3th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 16,668 mm³, 13.0% below the reference mean. With a Z-score of -1.13 (12.9th percentile), this represents mild atrophy. ",
  "text_data": "Age is 79.4 years. Gender is Female. Education: 19 years. MMSE: 29.0. Logical Memory: 7.0. APOEε4 alleles: 1.0. Biomarker levels: Pittsburgh compound B: 1.94 SUVR (normal ); Amyloid beta: 632.60 pg/mL (mild reduced); Total tau: 294.40 pg/mL (normal ); Phosphorylated tau: 29.78 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows mild to moderate atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside mildly reduced Aβ and elevated P-tau, suggesting early neurodegenerative changes. However, the MMSE score of 29 is within the normal range, indicating preserved cognitive function.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely prodromal Alzheimer's given biomarker and atrophy patterns).  \n\n**Confidence:** **Medium** (high biomarker/imaging consistency with early AD, but cognitive performance remains intact, requiring longitudinal follow-up).",
  "timestamp": "2025-07-26T03:13:08.259781"
}