{
  "ptid_time": "010_S_0904_2009-01-28",
  "img_path": "/data/qiuhui/data/adni/images/010_S_0904/2009-01-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 65,727 mm³, 39.8% above the reference mean. With a Z-score of 1.16 (87.6th percentile), this represents mild enlargement; hippocampal volume measures 7,150 mm³, 2.6% above the reference mean. With a Z-score of 0.23 (58.9th percentile), this represents normal volume ; whole brain volume measures 1,090,100 mm³, 5.9% above the reference mean. With a Z-score of 0.78 (78.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,285 mm³, 17.2% below the reference mean. With a Z-score of -1.13 (13.0th percentile), this represents mild atrophy; fusiform gyrus volume measures 19,247 mm³, 6.5% above the reference mean. With a Z-score of 0.57 (71.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,673 mm³, 2.5% above the reference mean. With a Z-score of 0.22 (58.8th percentile), this represents normal volume . ",
  "text_data": "Age is 86.1 years. Gender is Male. Education: 16 years. MMSE: 25.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 399.20 pg/mL (moderate reduced); Total tau: 477.20 pg/mL (significant elevated); Phosphorylated tau: 54.41 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild ventricular enlargement and mild entorhinal cortex atrophy, which are suggestive of early neurodegenerative changes. Elevated T-tau and P-tau levels, along with moderately reduced Aβ, support Alzheimer's pathology, but the MMSE score of 25 is borderline and hippocampal volume is normal, complicating the picture.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarkers and preserved hippocampal volume despite tau pathology)",
  "timestamp": "2025-07-25T22:34:45.705029"
}