{
  "ptid_time": "006_S_4150_2011-11-07",
  "img_path": "/data/qiuhui/data/adni/images/006_S_4150/2011-11-07/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 20,422 mm³, 47.0% below the reference mean. With a Z-score of -1.13 (13.0th percentile), this represents mild atrophy; hippocampal volume measures 8,568 mm³, 13.3% above the reference mean. With a Z-score of 1.30 (90.4th percentile), this represents mild enlargement; whole brain volume measures 1,098,870 mm³, 1.8% above the reference mean. With a Z-score of 0.23 (59.3th percentile), this represents normal volume ; entorhinal cortex volume measures 4,666 mm³, 13.8% above the reference mean. With a Z-score of 0.94 (82.5th percentile), this represents normal volume ; fusiform gyrus volume measures 19,427 mm³, 3.1% above the reference mean. With a Z-score of 0.27 (60.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,040 mm³, 15.5% below the reference mean. With a Z-score of -1.39 (8.2th percentile), this represents mild atrophy. ",
  "text_data": "Age is 73.9 years. Gender is Male. Education: 14 years. Handedness: Left. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Smoking. MMSE: 28.0. MoCA: 25.0. Logical Memory: 14.0. Laboratory findings: Hematocrit: 51.00 (significant elevated); Hemoglobin: 17.90 (profound elevated); Creatinine (Rate Blanked): 1.40 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.97 SUVR (normal ); Total tau: 227.00 pg/mL (normal ); Phosphorylated tau: 19.39 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild ventricular and middle temporal gyrus atrophy, but hippocampal, entorhinal cortex, fusiform gyrus, and whole brain volumes are normal or even slightly enlarged. Cognitive scores (MMSE 28, MoCA 25) are within normal limits, and biomarkers (T-tau, P-tau, AV45) are unremarkable. APOE4-negative status further reduces Alzheimer’s risk.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T21:34:13.027796"
}