{
  "ptid_time": "002_S_1261_2013-02-27",
  "img_path": "/data/qiuhui/data/adni/images/002_S_1261/2013-02-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 43,838 mm³, 56.2% above the reference mean. With a Z-score of 1.29 (90.1th percentile), this represents mild enlargement; hippocampal volume measures 5,574 mm³, 21.7% below the reference mean. With a Z-score of -1.99 (2.4th percentile), this represents moderate atrophy; whole brain volume measures 999,362 mm³, 2.5% above the reference mean. With a Z-score of 0.32 (62.5th percentile), this represents normal volume ; entorhinal cortex volume measures 2,582 mm³, 29.7% below the reference mean. With a Z-score of -1.82 (3.4th percentile), this represents moderate atrophy; fusiform gyrus volume measures 16,491 mm³, 3.1% below the reference mean. With a Z-score of -0.28 (39.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,837 mm³, 3.5% above the reference mean. With a Z-score of 0.30 (61.9th percentile), this represents normal volume . ",
  "text_data": "Age is 77.1 years. Gender is Female. Education: 16 years. MMSE: 30.0. MoCA: 27.0. Logical Memory: 12.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.05 SUVR (normal ); Amyloid beta: 1574.00 pg/mL (mild elevated); Total tau: 231.60 pg/mL (normal ); Phosphorylated tau: 21.23 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "Reasoning: The imaging data shows moderate atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease, alongside mild ventricular enlargement. However, cognitive scores (MMSE 30, MoCA 27) are within normal limits, and CSF biomarkers (Aβ mildly elevated but T-tau/P-tau normal) do not strongly support active neurodegeneration.  \n\nDiagnosis: **Mild Cognitive Impairment (MCI)**  \nConfidence: **Medium** (Structural changes suggest early pathology, but cognitive performance and biomarker profile are not fully consistent with dementia.)",
  "timestamp": "2025-07-25T20:13:38.301631"
}