{
  "ptid_time": "005_S_1224_2008-10-06",
  "img_path": "/data/qiuhui/data/adni/images/005_S_1224/2008-10-06/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 5,630 mm³, 19.2% below the reference mean. With a Z-score of -1.66 (4.9th percentile), this represents moderate atrophy; whole brain volume measures 1,019,500 mm³, 0.9% below the reference mean. With a Z-score of -0.12 (45.1th percentile), this represents normal volume ; entorhinal cortex volume measures 2,597 mm³, 34.6% below the reference mean. With a Z-score of -2.26 (1.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,625 mm³, 13.5% below the reference mean. With a Z-score of -1.17 (12.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 18,759 mm³, 7.0% below the reference mean. With a Z-score of -0.63 (26.5th percentile), this represents normal volume . ",
  "text_data": "Age is 82.6 years. Gender is Male. Education: 16 years. MMSE: 29.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The patient shows significant atrophy in the entorhinal cortex and moderate atrophy in the hippocampus, both key regions affected in Alzheimer's disease. However, cognitive function (MMSE 29) remains intact, and whole-brain volume is normal, suggesting no widespread neurodegeneration yet.  \nDiagnosis: **MCI** (Mild Cognitive Impairment)  \nConfidence: **Medium** (Structural changes are concerning, but preserved cognition complicates a dementia diagnosis at this stage.)",
  "timestamp": "2025-07-25T21:17:40.321200"
}