{
  "ptid_time": "073_S_5227_2013-06-17",
  "img_path": "/data/qiuhui/data/adni/images/073_S_5227/2013-06-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 29,486 mm³, 23.4% below the reference mean. With a Z-score of -0.56 (28.7th percentile), this represents normal volume ; hippocampal volume measures 7,631 mm³, 1.0% above the reference mean. With a Z-score of 0.09 (53.7th percentile), this represents normal volume ; whole brain volume measures 1,116,220 mm³, 3.4% above the reference mean. With a Z-score of 0.44 (67.1th percentile), this represents normal volume ; entorhinal cortex volume measures 4,088 mm³, 0.3% below the reference mean. With a Z-score of -0.02 (49.2th percentile), this represents normal volume ; fusiform gyrus volume measures 20,365 mm³, 8.1% above the reference mean. With a Z-score of 0.69 (75.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,042 mm³, 20.1% below the reference mean. With a Z-score of -1.81 (3.5th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 71.3 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Alcohol Abuse; Drug Abuse; Smoking; Major Surgical Procedures. MMSE: 30.0. MoCA: 25.0. Logical Memory: 10.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.08 SUVR (normal ); Amyloid beta: 648.90 pg/mL (normal ); Total tau: 492.10 pg/mL (profound elevated); Phosphorylated tau: 50.76 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show normal volumes in most regions except for moderate atrophy in the middle temporal gyrus. Cognitive testing (MMSE 30, MoCA 25) suggests mild cognitive impairment (MCI), supported by elevated T-tau and P-tau despite normal Aβ and AV45.  \n**Diagnosis:** MCI  \n**Confidence:** Medium  \n\n*(Confidence is Medium due to the discrepancy between normal Aβ and elevated tau, which complicates the typical AD biomarker profile, but the cognitive scores and temporal atrophy strongly suggest MCI.)*",
  "timestamp": "2025-07-26T09:54:59.195009"
}