{
  "ptid_time": "067_S_0336_2006-12-11",
  "img_path": "/data/qiuhui/data/adni/images/067_S_0336/2006-12-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 28,461 mm³, 26.1% below the reference mean. With a Z-score of -0.63 (26.6th percentile), this represents normal volume ; hippocampal volume measures 5,212 mm³, 31.1% below the reference mean. With a Z-score of -3.03 (0.1th percentile), this represents profound atrophy; whole brain volume measures 950,144 mm³, 12.0% below the reference mean. With a Z-score of -1.55 (6.0th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,870 mm³, 30.0% below the reference mean. With a Z-score of -2.04 (2.1th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,793 mm³, 37.4% below the reference mean. With a Z-score of -3.19 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 12,777 mm³, 40.1% below the reference mean. With a Z-score of -3.61 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 76.6 years. Gender is Male. Education: 17 years. MMSE: 21.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) alongside moderate whole-brain atrophy, consistent with neurodegenerative disease. The MMSE score of 21 (indicating cognitive impairment) and APOE4 positivity further support an Alzheimer's-like pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T08:30:02.053746"
}