{
  "ptid_time": "128_S_0740_2007-08-17",
  "img_path": "/data/qiuhui/data/adni/images/128_S_0740/2007-08-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,171 mm³, 27.7% above the reference mean. With a Z-score of 0.66 (74.6th percentile), this represents normal volume ; hippocampal volume measures 5,522 mm³, 26.9% below the reference mean. With a Z-score of -2.63 (0.4th percentile), this represents significant atrophy; whole brain volume measures 1,004,130 mm³, 7.0% below the reference mean. With a Z-score of -0.91 (18.3th percentile), this represents normal volume ; entorhinal cortex volume measures 2,651 mm³, 35.4% below the reference mean. With a Z-score of -2.40 (0.8th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,242 mm³, 24.4% below the reference mean. With a Z-score of -2.08 (1.9th percentile), this represents significant atrophy; middle temporal gyrus volume measures 15,094 mm³, 29.3% below the reference mean. With a Z-score of -2.63 (0.4th percentile), this represents significant atrophy. ",
  "text_data": "Age is 73.2 years. Gender is Male. Education: 15 years. MMSE: 20.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside a low MMSE score (20/30) and APOE4 positivity. These findings strongly suggest neurodegenerative pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given the pattern of atrophy and APOE4 status).  \n\n**Confidence:** **High** (consistent structural and clinical biomarkers of neurodegeneration).",
  "timestamp": "2025-07-26T13:49:27.095830"
}