{
  "ptid_time": "128_S_0310_2006-10-30",
  "img_path": "/data/qiuhui/data/adni/images/128_S_0310/2006-10-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 57,911 mm³, 23.2% above the reference mean. With a Z-score of 0.67 (75.0th percentile), this represents normal volume ; hippocampal volume measures 4,152 mm³, 40.4% below the reference mean. With a Z-score of -3.49 (0.0th percentile), this represents profound atrophy; whole brain volume measures 895,815 mm³, 13.0% below the reference mean. With a Z-score of -1.70 (4.5th percentile), this represents moderate atrophy; entorhinal cortex volume measures 1,896 mm³, 52.2% below the reference mean. With a Z-score of -3.42 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 12,570 mm³, 30.4% below the reference mean. With a Z-score of -2.63 (0.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 12,795 mm³, 36.6% below the reference mean. With a Z-score of -3.28 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 83.2 years. Gender is Male. Education: 16 years. MMSE: 24.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus, entorhinal cortex, and middle temporal gyrus—key regions affected in Alzheimer’s disease (AD). The MMSE score of 24 suggests mild cognitive impairment, but the severe atrophy in AD-vulnerable regions strongly indicates dementia. The absence of APOE4 does not rule out AD, as atrophy patterns are highly suggestive.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T13:44:55.509798"
}