{
  "ptid_time": "041_S_4974_2014-11-11",
  "img_path": "/data/qiuhui/data/adni/images/041_S_4974/2014-11-11/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 6,790 mm³, 10.2% below the reference mean. With a Z-score of -0.99 (16.0th percentile), this represents normal volume ; whole brain volume measures 1,170,560 mm³, 8.4% above the reference mean. With a Z-score of 1.10 (86.4th percentile), this represents mild enlargement. ",
  "text_data": "Age is 75.4 years. Gender is Male. Education: 19 years. MMSE: 28.0. MoCA: 24.0. Logical Memory: 9.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.37 SUVR (significant elevated); Amyloid beta: 710.10 pg/mL (normal ); Total tau: 788.30 pg/mL (profound elevated); Phosphorylated tau: 92.67 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume is within normal limits, and whole brain volume is mildly enlarged, suggesting no significant atrophy. However, the MoCA score of 24 indicates mild cognitive impairment (MCI), supported by profoundly elevated T-tau and P-tau levels, along with significant Aβ deposition (AV45), despite normal Aβ levels.  \n\n**Diagnosis:** **MCI** (likely prodromal Alzheimer’s due to biomarker profile)  \n**Confidence:** **Medium** (cognitive scores suggest MCI, but biomarker profile is strongly AD-like despite normal hippocampal volume)",
  "timestamp": "2025-07-26T07:22:34.759222"
}