{
  "ptid_time": "022_S_2379_2017-05-03",
  "img_path": "/data/qiuhui/data/adni/images/022_S_2379/2017-05-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 28,420 mm³, 26.2% below the reference mean. With a Z-score of -0.63 (26.5th percentile), this represents normal volume ; hippocampal volume measures 9,376 mm³, 24.0% above the reference mean. With a Z-score of 2.34 (99.0th percentile), this represents significant enlargement; whole brain volume measures 1,127,750 mm³, 4.5% above the reference mean. With a Z-score of 0.58 (72.0th percentile), this represents normal volume ; entorhinal cortex volume measures 4,137 mm³, 0.9% above the reference mean. With a Z-score of 0.06 (52.4th percentile), this represents normal volume ; fusiform gyrus volume measures 23,938 mm³, 27.1% above the reference mean. With a Z-score of 2.31 (98.9th percentile), this represents significant enlargement; middle temporal gyrus volume measures 22,954 mm³, 7.6% above the reference mean. With a Z-score of 0.68 (75.2th percentile), this represents normal volume . ",
  "text_data": "Age is 72.0 years. Gender is Male. Education: 18 years. MMSE: 29.0. MoCA: 26.0. Logical Memory: 17.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.10 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows significant enlargement in the hippocampus and fusiform gyrus, which is atypical for Alzheimer's disease (AD) as these regions typically atrophy in AD. Ventricular, whole brain, entorhinal cortex, and middle temporal gyrus volumes are normal. Cognitive scores (MMSE 29, MoCA 26) are within normal limits, and amyloid PET (AV45) is negative, ruling out significant amyloid pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T02:16:40.696170"
}