{
  "ptid_time": "021_S_0332_2007-04-19",
  "img_path": "/data/qiuhui/data/adni/images/021_S_0332/2007-04-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 60,847 mm³, 58.0% above the reference mean. With a Z-score of 1.39 (91.8th percentile), this represents mild enlargement; hippocampal volume measures 4,022 mm³, 46.8% below the reference mean. With a Z-score of -4.56 (0.0th percentile), this represents profound atrophy; whole brain volume measures 931,339 mm³, 13.7% below the reference mean. With a Z-score of -1.78 (3.7th percentile), this represents moderate atrophy; entorhinal cortex volume measures 1,940 mm³, 52.7% below the reference mean. With a Z-score of -3.57 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 18,070 mm³, 4.1% below the reference mean. With a Z-score of -0.35 (36.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,498 mm³, 13.3% below the reference mean. With a Z-score of -1.20 (11.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 70.9 years. Gender is Male. Education: 16 years. MMSE: 21.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). Moderate whole-brain atrophy and mild ventricular enlargement further support neurodegeneration. The MMSE score of 21 indicates cognitive impairment, and the absence of APOE4 does not rule out AD, as sporadic cases are common.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T01:26:13.834375"
}