{
  "ptid_time": "002_S_1070_2006-12-18",
  "img_path": "/data/qiuhui/data/adni/images/002_S_1070/2006-12-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 40,410 mm³, 4.9% above the reference mean. With a Z-score of 0.12 (54.7th percentile), this represents normal volume ; hippocampal volume measures 8,406 mm³, 11.2% above the reference mean. With a Z-score of 1.09 (86.3th percentile), this represents mild enlargement; whole brain volume measures 1,150,390 mm³, 6.6% above the reference mean. With a Z-score of 0.85 (80.3th percentile), this represents normal volume ; entorhinal cortex volume measures 4,007 mm³, 2.3% below the reference mean. With a Z-score of -0.15 (43.9th percentile), this represents normal volume ; fusiform gyrus volume measures 15,092 mm³, 19.9% below the reference mean. With a Z-score of -1.69 (4.5th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 18,663 mm³, 12.5% below the reference mean. With a Z-score of -1.13 (13.0th percentile), this represents mild atrophy. ",
  "text_data": "Age is 73.6 years. Gender is Male. Education: 14 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Hematopoietic-Lymphatic; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 1.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows **moderate atrophy in the fusiform gyrus** and **mild atrophy in the middle temporal gyrus**, both of which are associated with Alzheimer's pathology. However, hippocampal volume is **mildly enlarged**, and other regions (ventricular, whole brain, entorhinal cortex) are within normal ranges. The **MMSE of 25** is borderline, but the absence of APOE4 reduces genetic risk.  \n\n**Diagnosis: Mild Cognitive Impairment (MCI)**  \n**Confidence: Medium** (Atrophy in key regions suggests early neurodegeneration, but preserved hippocampal volume and lack of APOE4 make dementia less likely at this stage.)",
  "timestamp": "2025-07-25T20:09:56.269042"
}