{
  "ptid_time": "130_S_1201_2008-02-04",
  "img_path": "/data/qiuhui/data/adni/images/130_S_1201/2008-02-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 74,740 mm³, 166.3% above the reference mean. With a Z-score of 3.81 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,946 mm³, 30.5% below the reference mean. With a Z-score of -2.80 (0.3th percentile), this represents significant atrophy; whole brain volume measures 957,504 mm³, 1.8% below the reference mean. With a Z-score of -0.22 (41.2th percentile), this represents normal volume ; entorhinal cortex volume measures 1,735 mm³, 52.8% below the reference mean. With a Z-score of -3.24 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 14,153 mm³, 16.8% below the reference mean. With a Z-score of -1.53 (6.3th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,810 mm³, 17.5% below the reference mean. With a Z-score of -1.52 (6.4th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 76.5 years. Gender is Female. Education: 16 years. MMSE: 23.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD), along with moderate atrophy in the fusiform gyrus and middle temporal gyrus. The MMSE score of 23 suggests mild cognitive impairment, and the absence of APOE4 does not rule out AD, as neurodegeneration patterns are strongly indicative.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T14:34:58.328297"
}