{
  "ptid_time": "018_S_0335_2006-11-28",
  "img_path": "/data/qiuhui/data/adni/images/018_S_0335/2006-11-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 58,415 mm³, 58.0% above the reference mean. With a Z-score of 1.57 (94.1th percentile), this represents moderate enlargement; hippocampal volume measures 4,745 mm³, 26.9% below the reference mean. With a Z-score of -2.16 (1.5th percentile), this represents significant atrophy; whole brain volume measures 958,661 mm³, 3.3% above the reference mean. With a Z-score of 0.39 (65.3th percentile), this represents normal volume ; entorhinal cortex volume measures 1,946 mm³, 43.8% below the reference mean. With a Z-score of -2.36 (0.9th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,366 mm³, 10.8% below the reference mean. With a Z-score of -0.81 (20.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 15,890 mm³, 11.9% below the reference mean. With a Z-score of -1.06 (14.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 83.9 years. Gender is Female. Education: 14 years. MMSE: 19.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in the hippocampus and entorhinal cortex, both critical regions for memory and early Alzheimer's pathology. Moderate ventricular enlargement and mild atrophy in the middle temporal gyrus further support neurodegenerative changes. The MMSE score of 19 indicates cognitive impairment consistent with dementia.  \n\n**Diagnosis:** Dementia  \n**Confidence:** High",
  "timestamp": "2025-07-26T00:46:50.686959"
}