{
  "ptid_time": "021_S_4245_2011-09-22",
  "img_path": "/data/qiuhui/data/adni/images/021_S_4245/2011-09-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 67,444 mm³, 75.1% above the reference mean. With a Z-score of 1.80 (96.4th percentile), this represents moderate enlargement; whole brain volume measures 979,880 mm³, 9.2% below the reference mean. With a Z-score of -1.20 (11.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 73.6 years. Gender is Male. Education: 19 years. Handedness: Right. Race: Asian. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Dermatologic-Connective Tissue; Endocrine-Metabolic; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking. MMSE: 26.0. MoCA: 20.0. Logical Memory: 9.0. Laboratory findings: Total Bilirubin: 0.90 (significant elevated); Creatine Kinase: 198.00 (significant elevated); Phosphorus: 2.60 (significant reduced). APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 0.93 SUVR (mild reduced); Amyloid beta: 924.40 pg/mL (normal ); Total tau: 125.00 pg/mL (mild reduced); Phosphorylated tau: 9.22 pg/mL (moderate reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular enlargement and mild whole brain atrophy, which are structural changes often associated with cognitive decline. The MMSE score of 26 is borderline normal, while the MoCA score of 20 suggests mild cognitive impairment (MCI). The normal Aβ but reduced tau and AV45 levels suggest a non-Alzheimer's pathology or an early stage where amyloid accumulation may not yet be prominent.  \n\n**Diagnosis:** MCI  \n**Confidence:** Medium (due to conflicting biomarkers and borderline cognitive scores)",
  "timestamp": "2025-07-26T01:41:11.512730"
}