{
  "ptid_time": "137_S_1414_2015-09-09",
  "img_path": "/data/qiuhui/data/adni/images/137_S_1414/2015-09-09/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 40,439 mm³, 14.0% below the reference mean. With a Z-score of -0.41 (34.2th percentile), this represents normal volume ; hippocampal volume measures 5,608 mm³, 19.5% below the reference mean. With a Z-score of -1.69 (4.6th percentile), this represents moderate atrophy; whole brain volume measures 995,280 mm³, 3.3% below the reference mean. With a Z-score of -0.43 (33.3th percentile), this represents normal volume . ",
  "text_data": "Age is 82.3 years. Gender is Male. Education: 18 years. MMSE: 26.0. MoCA: 21.0. Logical Memory: 4.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.25 SUVR (mild elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows moderate atrophy (Z-score -1.69, 4.6th percentile), which is a strong biomarker for Alzheimer's pathology, while ventricular and whole brain volumes are normal. The MMSE (26) is borderline, but the MoCA (21) suggests mild cognitive impairment. The presence of APOE4 and mild AV45 (amyloid) elevation further supports Alzheimer's-related changes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T16:27:22.117924"
}