{
  "ptid_time": "131_S_0497_2007-06-19",
  "img_path": "/data/qiuhui/data/adni/images/131_S_0497/2007-06-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 95,006 mm³, 146.7% above the reference mean. With a Z-score of 3.51 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,346 mm³, 16.0% below the reference mean. With a Z-score of -1.57 (5.9th percentile), this represents moderate atrophy; whole brain volume measures 1,094,290 mm³, 1.4% above the reference mean. With a Z-score of 0.18 (57.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,153 mm³, 23.1% below the reference mean. With a Z-score of -1.57 (5.9th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,799 mm³, 0.2% below the reference mean. With a Z-score of -0.02 (49.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,932 mm³, 1.9% below the reference mean. With a Z-score of -0.17 (43.2th percentile), this represents normal volume . ",
  "text_data": "Age is 76.7 years. Gender is Male. Education: 12 years. MMSE: 23.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.51) and moderate atrophy in the hippocampus (Z-score -1.57) and entorhinal cortex (Z-score -1.57), which are key regions affected in Alzheimer's disease. The MMSE score of 23.0 (below the typical cutoff of 24 for normal cognition) and the presence of two APOE4 alleles further support cognitive impairment.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T15:09:24.212398"
}