{
  "ptid_time": "073_S_4312_2011-10-17",
  "img_path": "/data/qiuhui/data/adni/images/073_S_4312/2011-10-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,675 mm³, 27.8% below the reference mean. With a Z-score of -0.66 (25.4th percentile), this represents normal volume ; hippocampal volume measures 7,364 mm³, 8.3% below the reference mean. With a Z-score of -0.83 (20.5th percentile), this represents normal volume ; whole brain volume measures 1,050,200 mm³, 7.4% below the reference mean. With a Z-score of -1.05 (14.6th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,644 mm³, 8.9% above the reference mean. With a Z-score of 0.62 (73.2th percentile), this represents normal volume ; fusiform gyrus volume measures 18,470 mm³, 7.2% below the reference mean. With a Z-score of -0.60 (27.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,470 mm³, 4.2% below the reference mean. With a Z-score of -0.35 (36.5th percentile), this represents normal volume . ",
  "text_data": "Age is 69.3 years. Gender is Male. Education: 17 years. Handedness: Left. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Gastrointestinal; Major Surgical Procedures. MMSE: 26.0. MoCA: 24.0. Logical Memory: 9.0. Laboratory findings: Eosinophils: 0.41 (significant elevated); Eosinophils: 6.90 (profound elevated). APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.10 SUVR (normal ); Amyloid beta: 666.20 pg/mL (normal ); Total tau: 248.80 pg/mL (normal ); Phosphorylated tau: 20.75 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show mild whole-brain atrophy but otherwise normal regional volumes (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus). Cognitive scores (MMSE 26, MoCA 24) are slightly below optimal but not in the dementia range. Biomarkers (Aβ, tau, AV45) are normal, and APOE4 status (heterozygous) does not strongly indicate Alzheimer’s pathology.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (Mild atrophy and borderline cognitive scores could suggest early changes, but biomarker normality supports CN.)",
  "timestamp": "2025-07-26T09:43:18.047203"
}