{
  "ptid_time": "041_S_4200_2015-10-06",
  "img_path": "/data/qiuhui/data/adni/images/041_S_4200/2015-10-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 23,380 mm³, 16.7% below the reference mean. With a Z-score of -0.38 (35.1th percentile), this represents normal volume ; hippocampal volume measures 7,457 mm³, 4.8% above the reference mean. With a Z-score of 0.44 (67.1th percentile), this represents normal volume ; whole brain volume measures 1,046,860 mm³, 7.4% above the reference mean. With a Z-score of 0.93 (82.4th percentile), this represents normal volume ; entorhinal cortex volume measures 4,498 mm³, 22.5% above the reference mean. With a Z-score of 1.38 (91.6th percentile), this represents mild enlargement; fusiform gyrus volume measures 16,557 mm³, 2.7% below the reference mean. With a Z-score of -0.24 (40.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,012 mm³, 14.8% above the reference mean. With a Z-score of 1.29 (90.1th percentile), this represents mild enlargement. ",
  "text_data": "Age is 74.2 years. Gender is Female. Education: 18 years. MMSE: 30.0. MoCA: 28.0. Logical Memory: 17.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.06 SUVR (normal ); Amyloid beta: 1583.00 pg/mL (mild elevated); Total tau: 168.70 pg/mL (normal ); Phosphorylated tau: 14.88 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** All brain volume measures (hippocampus, whole brain, entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges or even mildly enlarged, with no significant atrophy. Cognitive scores (MMSE 30, MoCA 28) are intact, and CSF biomarkers (Aβ mildly elevated but T-tau/P-tau normal) do not strongly support Alzheimer’s pathology. APOE4-negative status further reduces AD risk.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T07:15:02.053730"
}