{
  "ptid_time": "053_S_0389_2010-05-05",
  "img_path": "/data/qiuhui/data/adni/images/053_S_0389/2010-05-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,420 mm³, 72.5% above the reference mean. With a Z-score of 1.66 (95.2th percentile), this represents moderate enlargement; hippocampal volume measures 4,247 mm³, 40.3% below the reference mean. With a Z-score of -3.70 (0.0th percentile), this represents profound atrophy; whole brain volume measures 990,335 mm³, 1.6% above the reference mean. With a Z-score of 0.20 (58.0th percentile), this represents normal volume ; entorhinal cortex volume measures 1,793 mm³, 51.2% below the reference mean. With a Z-score of -3.14 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 16,640 mm³, 2.2% below the reference mean. With a Z-score of -0.20 (42.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,573 mm³, 13.5% below the reference mean. With a Z-score of -1.18 (12.0th percentile), this represents mild atrophy. ",
  "text_data": "Age is 75.5 years. Gender is Female. Education: 16 years. MMSE: 26.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). The MMSE score of 26 is borderline, but the structural changes strongly suggest neurodegeneration. The presence of one APOE4 allele further increases AD risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T07:53:57.101028"
}