{
  "ptid_time": "082_S_1079_2007-06-11",
  "img_path": "/data/qiuhui/data/adni/images/082_S_1079/2007-06-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 91,431 mm³, 137.4% above the reference mean. With a Z-score of 3.29 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,646 mm³, 38.5% below the reference mean. With a Z-score of -3.76 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,073,900 mm³, 0.5% below the reference mean. With a Z-score of -0.07 (47.4th percentile), this represents normal volume ; entorhinal cortex volume measures 1,942 mm³, 52.6% below the reference mean. With a Z-score of -3.57 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 15,011 mm³, 20.3% below the reference mean. With a Z-score of -1.73 (4.2th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 13,811 mm³, 35.3% below the reference mean. With a Z-score of -3.17 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 78.5 years. Gender is Male. Education: 18 years. MMSE: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, middle temporal gyrus) alongside severe ventricular enlargement, consistent with neurodegeneration. The MMSE score of 23 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T10:00:19.095669"
}