{
  "ptid_time": "009_S_1354_2007-03-06",
  "img_path": "/data/qiuhui/data/adni/images/009_S_1354/2007-03-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,396 mm³, 14.9% above the reference mean. With a Z-score of 0.43 (66.5th percentile), this represents normal volume ; hippocampal volume measures 4,309 mm³, 44.8% below the reference mean. With a Z-score of -6.23 (0.0th percentile), this represents profound atrophy; whole brain volume measures 813,683 mm³, 21.8% below the reference mean. With a Z-score of -2.61 (0.4th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,201 mm³, 40.4% below the reference mean. With a Z-score of -3.16 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,941 mm³, 35.2% below the reference mean. With a Z-score of -3.20 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 11,332 mm³, 44.8% below the reference mean. With a Z-score of -3.70 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 58.9 years. Gender is Female. Education: 16 years. Handedness: Right. Race: Black or African American. Medical history: Psychiatric; Cardiovascular; Endocrine-Metabolic. MMSE: 20.0. Logical Memory: 2.0. APOEε4 alleles: 2.0. Biomarker levels: Amyloid beta: 543.50 pg/mL (mild reduced); Total tau: 477.90 pg/mL (profound elevated); Phosphorylated tau: 46.54 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) and significant whole-brain atrophy, alongside elevated tau biomarkers (T-tau, P-tau) and mild Aβ reduction. The MMSE score of 20 indicates cognitive impairment.  \n**Diagnosis:** Dementia (likely Alzheimer's disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T22:15:50.921195"
}