{
  "ptid_time": "067_S_4782_2012-07-26",
  "img_path": "/data/qiuhui/data/adni/images/067_S_4782/2012-07-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 38,206 mm³, 0.8% below the reference mean. With a Z-score of -0.02 (49.2th percentile), this represents normal volume ; hippocampal volume measures 6,317 mm³, 16.4% below the reference mean. With a Z-score of -1.60 (5.4th percentile), this represents moderate atrophy; whole brain volume measures 1,090,990 mm³, 1.1% above the reference mean. With a Z-score of 0.14 (55.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,714 mm³, 9.4% below the reference mean. With a Z-score of -0.64 (26.1th percentile), this represents normal volume ; fusiform gyrus volume measures 16,792 mm³, 10.9% below the reference mean. With a Z-score of -0.93 (17.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,730 mm³, 7.5% below the reference mean. With a Z-score of -0.68 (24.9th percentile), this represents normal volume . ",
  "text_data": "Age is 71.9 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Respiratory; Gastrointestinal; Major Surgical Procedures. MMSE: 28.0. MoCA: 23.0. Logical Memory: 6.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.10 SUVR (normal ); Amyloid beta: 312.30 pg/mL (moderate reduced); Total tau: 216.00 pg/mL (normal ); Phosphorylated tau: 20.02 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows moderate atrophy (Z-score -1.60, 5.4th percentile), which is a key biomarker for Alzheimer's disease, while other brain regions are within normal ranges. The MoCA score of 23 suggests mild cognitive impairment (MCI), and the presence of two APOE4 alleles along with moderately reduced Aβ supports an Alzheimer's pathological process.  \n\n**Diagnosis:** **MCI (likely due to Alzheimer’s disease)**  \n**Confidence:** **Medium** (due to normal MMSE and lack of significant atrophy in other regions, but strong hippocampal and biomarker evidence)",
  "timestamp": "2025-07-26T08:40:57.098713"
}