{
  "ptid_time": "002_S_4799_2016-07-26",
  "img_path": "/data/qiuhui/data/adni/images/002_S_4799/2016-07-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 43,196 mm³, 12.1% above the reference mean. With a Z-score of 0.29 (61.4th percentile), this represents normal volume ; hippocampal volume measures 7,864 mm³, 4.0% above the reference mean. With a Z-score of 0.39 (65.3th percentile), this represents normal volume ; whole brain volume measures 1,179,650 mm³, 9.3% above the reference mean. With a Z-score of 1.21 (88.6th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,848 mm³, 6.2% below the reference mean. With a Z-score of -0.42 (33.8th percentile), this represents normal volume ; fusiform gyrus volume measures 20,969 mm³, 11.3% above the reference mean. With a Z-score of 0.96 (83.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,215 mm³, 13.5% above the reference mean. With a Z-score of 1.21 (88.7th percentile), this represents mild enlargement. ",
  "text_data": "Age is 72.0 years. Gender is Male. Education: 14 years. MMSE: 30.0. MoCA: 25.0. Logical Memory: 13.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.40 SUVR (significant elevated); Amyloid beta: 611.30 pg/mL (mild reduced); Total tau: 232.50 pg/mL (normal ); Phosphorylated tau: 22.94 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges or mildly enlarged, with only the entorhinal cortex slightly below the reference mean (but still within normal Z-score range). Cognitive testing shows a perfect MMSE (30/30) and a slightly reduced MoCA (25/30), which may suggest very mild cognitive changes. Biomarkers indicate mildly reduced Aβ and significantly elevated AV45 (suggesting amyloid deposition), but normal tau levels.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Biomarkers suggest amyloid pathology, but cognitive scores are borderline, and structural changes are minimal.)",
  "timestamp": "2025-07-25T20:32:24.932664"
}