{
  "ptid_time": "021_S_0273_2007-05-29",
  "img_path": "/data/qiuhui/data/adni/images/021_S_0273/2007-05-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 45,129 mm³, 50.3% above the reference mean. With a Z-score of 1.20 (88.4th percentile), this represents mild enlargement; hippocampal volume measures 7,729 mm³, 3.7% below the reference mean. With a Z-score of -0.37 (35.5th percentile), this represents normal volume ; whole brain volume measures 1,061,450 mm³, 6.4% below the reference mean. With a Z-score of -0.91 (18.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,512 mm³, 17.6% below the reference mean. With a Z-score of -1.22 (11.1th percentile), this represents mild atrophy; fusiform gyrus volume measures 21,265 mm³, 6.8% above the reference mean. With a Z-score of 0.57 (71.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,847 mm³, 1.9% above the reference mean. With a Z-score of 0.16 (56.4th percentile), this represents normal volume . ",
  "text_data": "Age is 63.8 years. Gender is Male. Education: 12 years. MMSE: 29.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1646.00 pg/mL (moderate elevated); Total tau: 194.50 pg/mL (normal ); Phosphorylated tau: 16.34 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild ventricular enlargement and mild entorhinal cortex atrophy, but hippocampal and whole brain volumes are within normal ranges. The MMSE score of 29 is normal, and while Aβ is moderately elevated, tau levels are normal, suggesting early amyloid pathology without significant neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarkers—elevated Aβ but normal tau and mostly preserved brain volumes)",
  "timestamp": "2025-07-26T01:23:46.322727"
}