{
  "ptid_time": "135_S_4863_2012-08-01",
  "img_path": "/data/qiuhui/data/adni/images/135_S_4863/2012-08-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 24,040 mm³, 37.6% below the reference mean. With a Z-score of -0.90 (18.4th percentile), this represents normal volume ; hippocampal volume measures 7,155 mm³, 5.3% below the reference mean. With a Z-score of -0.52 (30.1th percentile), this represents normal volume ; whole brain volume measures 1,270,850 mm³, 17.7% above the reference mean. With a Z-score of 2.30 (98.9th percentile), this represents significant enlargement; entorhinal cortex volume measures 3,457 mm³, 15.7% below the reference mean. With a Z-score of -1.06 (14.4th percentile), this represents mild atrophy; fusiform gyrus volume measures 20,640 mm³, 9.6% above the reference mean. With a Z-score of 0.81 (79.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,744 mm³, 1.9% above the reference mean. With a Z-score of 0.17 (56.8th percentile), this represents normal volume . ",
  "text_data": "Age is 70.0 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Psychiatric; Endocrine-Metabolic; Smoking. MMSE: 26.0. MoCA: 22.0. Logical Memory: 5.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.38 SUVR (significant elevated); Amyloid beta: 449.40 pg/mL (moderate reduced); Total tau: 367.20 pg/mL (moderate elevated); Phosphorylated tau: 32.73 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The patient shows normal hippocampal and ventricular volumes but mild atrophy in the entorhinal cortex, which is often affected early in Alzheimer's disease. Cognitive scores (MMSE 26, MoCA 22) suggest mild cognitive impairment, and biomarker data (elevated Aβ, T-tau, P-tau, and AV45) strongly indicate Alzheimer's pathology.  \nDiagnosis: MCI (likely due to Alzheimer's disease)  \nConfidence: High",
  "timestamp": "2025-07-26T15:46:18.978990"
}