{
  "ptid_time": "052_S_4807_2012-07-27",
  "img_path": "/data/qiuhui/data/adni/images/052_S_4807/2012-07-27/t1.nii.gz",
  "img_finding": "",
  "text_data": "Age is 72.0 years. Gender is Female. Education: 16 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Endocrine-Metabolic; Allergies or Drug Sensitivities; Malignancy; Major Surgical Procedures. MMSE: 29.0. MoCA: 25.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.37 SUVR (significant elevated); Amyloid beta: 991.80 pg/mL (normal ); Total tau: 713.90 pg/mL (profound elevated); Phosphorylated tau: 86.51 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The MMSE and MoCA scores are within normal ranges (MMSE ≥26, MoCA ≥22), indicating no significant cognitive impairment. However, the profound elevation in T-tau and P-tau, along with significant AV45 (amyloid PET) elevation, suggests underlying Alzheimer's pathology despite normal Aβ levels. This may indicate early neurodegenerative changes before cognitive symptoms manifest.  \n\nDiagnosis: CN (Cognitively Normal)  \nConfidence: Medium (due to conflicting biomarkers—normal cognition but significant tau and amyloid pathology)",
  "timestamp": "2025-07-26T07:49:58.376625"
}