{
  "ptid_time": "100_S_0015_2006-10-17",
  "img_path": "/data/qiuhui/data/adni/images/100_S_0015/2006-10-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 33,920 mm³, 27.9% below the reference mean. With a Z-score of -0.81 (20.9th percentile), this represents normal volume ; hippocampal volume measures 7,160 mm³, 2.8% above the reference mean. With a Z-score of 0.24 (59.4th percentile), this represents normal volume ; whole brain volume measures 994,249 mm³, 3.4% below the reference mean. With a Z-score of -0.44 (32.8th percentile), this represents normal volume ; entorhinal cortex volume measures 3,947 mm³, 0.6% below the reference mean. With a Z-score of -0.04 (48.6th percentile), this represents normal volume ; fusiform gyrus volume measures 14,798 mm³, 18.1% below the reference mean. With a Z-score of -1.57 (5.9th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 18,177 mm³, 9.9% below the reference mean. With a Z-score of -0.89 (18.8th percentile), this represents normal volume . ",
  "text_data": "Age is 81.8 years. Gender is Male. Education: 18 years. MMSE: 27.0. Logical Memory: 15.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows normal volumes in most regions, including the hippocampus and entorhinal cortex, which are typically affected early in Alzheimer's disease. However, there is moderate atrophy in the fusiform gyrus, which may contribute to mild cognitive symptoms. The MMSE score of 27 is within the normal range for age, and the presence of one APOE4 allele increases Alzheimer's risk but does not confirm pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to isolated fusiform gyrus atrophy but otherwise normal cognitive and structural findings)",
  "timestamp": "2025-07-26T11:14:40.506726"
}