{
  "ptid_time": "023_S_4241_2012-05-01",
  "img_path": "/data/qiuhui/data/adni/images/023_S_4241/2012-05-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 34,024 mm³, 52.3% above the reference mean. With a Z-score of 1.31 (90.5th percentile), this represents mild enlargement; hippocampal volume measures 7,356 mm³, 4.3% below the reference mean. With a Z-score of -0.48 (31.6th percentile), this represents normal volume ; whole brain volume measures 1,103,330 mm³, 7.2% above the reference mean. With a Z-score of 0.90 (81.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,349 mm³, 14.0% below the reference mean. With a Z-score of -1.08 (13.9th percentile), this represents mild atrophy; fusiform gyrus volume measures 21,589 mm³, 18.6% above the reference mean. With a Z-score of 2.09 (98.2th percentile), this represents significant enlargement; middle temporal gyrus volume measures 22,101 mm³, 7.7% above the reference mean. With a Z-score of 0.68 (75.3th percentile), this represents normal volume . ",
  "text_data": "Age is 69.8 years. Gender is Female. Education: 18 years. MMSE: 30.0. MoCA: 25.0. Logical Memory: 9.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.35 SUVR (significant elevated); Amyloid beta: 731.90 pg/mL (normal ); Total tau: 301.20 pg/mL (normal ); Phosphorylated tau: 32.12 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild ventricular enlargement and mild entorhinal cortex atrophy, but hippocampal volume is normal. The MMSE is normal (30/30), but the MoCA is slightly below normal (25/30), suggesting possible mild cognitive impairment. Biomarkers show elevated AV45 (amyloid) and mildly elevated P-tau, but normal Aβ and T-tau, which could indicate early amyloid deposition without significant neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarkers—elevated AV45 but normal Aβ, and only mild structural changes with near-normal cognitive scores)",
  "timestamp": "2025-07-26T03:04:29.479536"
}