{
  "ptid_time": "009_S_4324_2013-12-17",
  "img_path": "/data/qiuhui/data/adni/images/009_S_4324/2013-12-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 65,032 mm³, 191.1% above the reference mean. With a Z-score of 4.78 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,108 mm³, 33.5% below the reference mean. With a Z-score of -3.76 (0.0th percentile), this represents profound atrophy; whole brain volume measures 817,341 mm³, 20.6% below the reference mean. With a Z-score of -2.56 (0.5th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,385 mm³, 38.7% below the reference mean. With a Z-score of -3.00 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 13,058 mm³, 28.3% below the reference mean. With a Z-score of -3.19 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 15,251 mm³, 25.7% below the reference mean. With a Z-score of -2.28 (1.1th percentile), this represents significant atrophy. ",
  "text_data": "Age is 64.8 years. Gender is Female. Education: 14 years. MMSE: 24.0. MoCA: 15.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus) alongside significant whole-brain atrophy and ventricular enlargement, consistent with advanced neurodegeneration. The cognitive scores (MMSE 24, MoCA 15) indicate moderate-to-severe impairment, and the presence of one APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T22:18:21.912890"
}