{
  "ptid_time": "941_S_6546_2018-08-08",
  "img_path": "/data/qiuhui/data/adni/images/941_S_6546/2018-08-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 63,380 mm³, 71.5% above the reference mean. With a Z-score of 1.93 (97.3th percentile), this represents moderate enlargement; hippocampal volume measures 6,215 mm³, 4.3% below the reference mean. With a Z-score of -0.35 (36.5th percentile), this represents normal volume ; whole brain volume measures 965,087 mm³, 4.0% above the reference mean. With a Z-score of 0.48 (68.3th percentile), this represents normal volume ; entorhinal cortex volume measures 4,447 mm³, 28.4% above the reference mean. With a Z-score of 1.53 (93.8th percentile), this represents moderate enlargement; fusiform gyrus volume measures 16,270 mm³, 1.0% above the reference mean. With a Z-score of 0.07 (53.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,618 mm³, 14.4% above the reference mean. With a Z-score of 1.28 (89.9th percentile), this represents mild enlargement. ",
  "text_data": "Age is 80.4 years. Gender is Female. Education: 20 years. Handedness: Right. Race: White. MMSE: 28.0. MoCA: 22.0. Logical Memory: 9.0. APOEε4 alleles: 1.0. Biomarker levels: Flobetaben (FBB): 0.99 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular enlargement (consistent with possible atrophy) and mild-to-moderate enlargement in the entorhinal cortex and middle temporal gyrus, which could suggest early neurodegenerative changes. However, hippocampal volume is normal, and cognitive scores (MMSE 28, MoCA 22) indicate only mild impairment, with the MoCA score being borderline for MCI.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting imaging findings—some atrophy markers but preserved hippocampus—and borderline cognitive scores)",
  "timestamp": "2025-07-26T17:49:13.645419"
}