{
  "ptid_time": "005_S_0814_2007-10-11",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0814/2007-10-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 76,934 mm³, 174.1% above the reference mean. With a Z-score of 3.99 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,759 mm³, 33.1% below the reference mean. With a Z-score of -3.04 (0.1th percentile), this represents profound atrophy; whole brain volume measures 844,971 mm³, 13.3% below the reference mean. With a Z-score of -1.67 (4.7th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,436 mm³, 33.7% below the reference mean. With a Z-score of -2.07 (1.9th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,571 mm³, 32.0% below the reference mean. With a Z-score of -2.91 (0.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,302 mm³, 30.6% below the reference mean. With a Z-score of -2.66 (0.4th percentile), this represents significant atrophy. ",
  "text_data": "Age is 72.0 years. Gender is Female. Education: 16 years. MMSE: 23.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.04) and significant atrophy in other memory-related regions (entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside ventricular enlargement (Z-score 3.99), strongly suggesting neurodegeneration. The MMSE score of 23 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T21:16:24.198241"
}