{
  "ptid_time": "023_S_0331_2006-10-03",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0331/2006-10-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 28,653 mm³, 28.3% above the reference mean. With a Z-score of 0.71 (76.0th percentile), this represents normal volume ; hippocampal volume measures 5,846 mm³, 23.9% below the reference mean. With a Z-score of -2.69 (0.4th percentile), this represents significant atrophy; whole brain volume measures 981,796 mm³, 4.6% below the reference mean. With a Z-score of -0.57 (28.3th percentile), this represents normal volume ; entorhinal cortex volume measures 2,044 mm³, 47.5% below the reference mean. With a Z-score of -3.68 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 14,920 mm³, 18.1% below the reference mean. With a Z-score of -2.03 (2.1th percentile), this represents significant atrophy; middle temporal gyrus volume measures 16,312 mm³, 20.5% below the reference mean. With a Z-score of -1.82 (3.4th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 65.1 years. Gender is Female. Education: 14 years. MMSE: 24.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant atrophy in the hippocampus, entorhinal cortex, fusiform gyrus, and middle temporal gyrus—key regions affected in Alzheimer’s disease. The MMSE score of 24 suggests mild cognitive impairment, and the presence of two APOE4 alleles increases Alzheimer’s risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T02:40:00.751160"
}