{
  "ptid_time": "057_S_0934_2015-10-14",
  "img_path": "/data/qiuhui/data/adni/images/057_S_0934/2015-10-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,170 mm³, 11.1% above the reference mean. With a Z-score of 0.25 (60.0th percentile), this represents normal volume ; hippocampal volume measures 6,655 mm³, 6.5% below the reference mean. With a Z-score of -0.59 (27.7th percentile), this represents normal volume ; whole brain volume measures 897,662 mm³, 7.9% below the reference mean. With a Z-score of -0.99 (16.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,654 mm³, 27.7% below the reference mean. With a Z-score of -1.70 (4.4th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,273 mm³, 7.4% above the reference mean. With a Z-score of 0.67 (75.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,590 mm³, 8.2% below the reference mean. With a Z-score of -0.72 (23.7th percentile), this represents normal volume . ",
  "text_data": "Age is 79.0 years. Gender is Female. Education: 10 years. MMSE: 30.0. MoCA: 27.0. Logical Memory: 12.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.01 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows moderate atrophy in the entorhinal cortex (Z-score -1.70, 4.4th percentile), which is a key region affected in early Alzheimer's disease. However, hippocampal and whole brain volumes are within normal ranges, and cognitive scores (MMSE 30, MoCA 27) are intact, suggesting no significant functional impairment. The absence of APOE4 and normal AV45 (amyloid PET) further reduce the likelihood of Alzheimer's pathology.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (due to entorhinal atrophy but otherwise normal biomarkers and cognition)",
  "timestamp": "2025-07-26T08:06:57.459121"
}