{
  "ptid_time": "099_S_0551_2006-05-18",
  "img_path": "/data/qiuhui/data/adni/images/099_S_0551/2006-05-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 18,273 mm³, 39.1% below the reference mean. With a Z-score of -0.93 (17.6th percentile), this represents normal volume ; hippocampal volume measures 7,102 mm³, 11.5% below the reference mean. With a Z-score of -1.15 (12.5th percentile), this represents mild atrophy; whole brain volume measures 1,112,060 mm³, 2.0% below the reference mean. With a Z-score of -0.28 (39.0th percentile), this represents normal volume ; entorhinal cortex volume measures 4,001 mm³, 6.1% below the reference mean. With a Z-score of -0.43 (33.5th percentile), this represents normal volume ; fusiform gyrus volume measures 16,481 mm³, 17.2% below the reference mean. With a Z-score of -1.43 (7.6th percentile), this represents mild atrophy; middle temporal gyrus volume measures 18,582 mm³, 17.1% below the reference mean. With a Z-score of -1.41 (8.0th percentile), this represents mild atrophy. ",
  "text_data": "Age is 64.2 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 29.0. Logical Memory: 8.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows mild atrophy (Z-score -1.15), and the fusiform gyrus and middle temporal gyrus also exhibit mild atrophy (Z-scores -1.43 and -1.41, respectively). However, other brain regions (ventricular, whole brain, entorhinal cortex) are within normal ranges. The MMSE score of 29 is normal, and there is no APOE4 risk allele.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural atrophy in key memory-related regions suggests MCI, but cognitive performance remains intact, and APOE4 status is negative.)",
  "timestamp": "2025-07-26T10:58:16.362671"
}