{
  "ptid_time": "098_S_4275_2012-03-27",
  "img_path": "/data/qiuhui/data/adni/images/098_S_4275/2012-03-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,429 mm³, 20.5% above the reference mean. With a Z-score of 0.49 (68.9th percentile), this represents normal volume ; hippocampal volume measures 7,912 mm³, 4.7% above the reference mean. With a Z-score of 0.46 (67.6th percentile), this represents normal volume ; whole brain volume measures 1,216,010 mm³, 12.7% above the reference mean. With a Z-score of 1.64 (95.0th percentile), this represents moderate enlargement; entorhinal cortex volume measures 4,432 mm³, 8.1% above the reference mean. With a Z-score of 0.55 (70.8th percentile), this represents normal volume ; fusiform gyrus volume measures 18,401 mm³, 2.3% below the reference mean. With a Z-score of -0.20 (42.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,891 mm³, 16.6% above the reference mean. With a Z-score of 1.50 (93.3th percentile), this represents mild enlargement. ",
  "text_data": "Age is 73.3 years. Gender is Male. Education: 18 years. MMSE: 30.0. MoCA: 24.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within or above the reference range, with no significant atrophy in key regions like the hippocampus or entorhinal cortex. The MMSE score of 30 is normal, but the MoCA score of 24 suggests possible mild cognitive impairment (MCI), though APOE4-negative status lowers Alzheimer's risk.  \n\n**Diagnosis:** **MCI** (due to MoCA score, despite normal imaging)  \n**Confidence:** **Medium** (imaging does not support neurodegeneration, but MoCA indicates cognitive concern)",
  "timestamp": "2025-07-26T10:48:42.973537"
}