{
  "ptid_time": "057_S_1007_2008-11-05",
  "img_path": "/data/qiuhui/data/adni/images/057_S_1007/2008-11-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 50,976 mm³, 32.3% above the reference mean. With a Z-score of 0.77 (78.1th percentile), this represents normal volume ; hippocampal volume measures 4,664 mm³, 38.3% below the reference mean. With a Z-score of -3.74 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,113,240 mm³, 3.1% above the reference mean. With a Z-score of 0.41 (65.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,495 mm³, 39.2% below the reference mean. With a Z-score of -2.66 (0.4th percentile), this represents significant atrophy; fusiform gyrus volume measures 17,339 mm³, 8.0% below the reference mean. With a Z-score of -0.68 (24.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,969 mm³, 11.1% below the reference mean. With a Z-score of -1.00 (15.9th percentile), this represents normal volume . ",
  "text_data": "Age is 74.3 years. Gender is Male. Education: 17 years. MMSE: 25.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal and entorhinal cortex volumes show profound and significant atrophy, respectively, which are hallmark features of Alzheimer's disease. The MMSE score of 25 is borderline, suggesting mild cognitive impairment, but the severe atrophy in memory-critical regions supports progression toward dementia.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** Medium (High confidence in neurodegeneration, but clinical correlation is needed for definitive dementia staging)",
  "timestamp": "2025-07-26T08:08:34.397566"
}