{
  "ptid_time": "027_S_0404_2008-05-13",
  "img_path": "/data/qiuhui/data/adni/images/027_S_0404/2008-05-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 35,651 mm³, 3.6% below the reference mean. With a Z-score of -0.10 (46.2th percentile), this represents normal volume ; hippocampal volume measures 3,896 mm³, 40.0% below the reference mean. With a Z-score of -3.21 (0.1th percentile), this represents profound atrophy; whole brain volume measures 753,171 mm³, 18.9% below the reference mean. With a Z-score of -2.26 (1.2th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,421 mm³, 59.0% below the reference mean. With a Z-score of -3.18 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,444 mm³, 29.0% below the reference mean. With a Z-score of -2.18 (1.5th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,899 mm³, 17.4% below the reference mean. With a Z-score of -1.55 (6.1th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 89.8 years. Gender is Female. Education: 14 years. MMSE: 20.0. Logical Memory: 0.0. Laboratory findings: Triglycerides (GPO): 425.00 (profound elevated). APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, along with significant whole-brain and fusiform gyrus atrophy, which are hallmark features of Alzheimer's disease. The MMSE score of 20.0 at age 89.8 is consistent with cognitive impairment, and the absence of APOE4 does not rule out AD given the strong structural evidence.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T03:36:53.436456"
}