{
  "ptid_time": "012_S_4545_2012-03-14",
  "img_path": "/data/qiuhui/data/adni/images/012_S_4545/2012-03-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 19,938 mm³, 10.7% below the reference mean. With a Z-score of -0.27 (39.4th percentile), this represents normal volume ; hippocampal volume measures 8,464 mm³, 10.1% above the reference mean. With a Z-score of 1.14 (87.3th percentile), this represents mild enlargement; whole brain volume measures 1,181,230 mm³, 14.8% above the reference mean. With a Z-score of 1.84 (96.7th percentile), this represents moderate enlargement; entorhinal cortex volume measures 3,826 mm³, 1.7% below the reference mean. With a Z-score of -0.13 (44.7th percentile), this represents normal volume ; fusiform gyrus volume measures 18,678 mm³, 2.6% above the reference mean. With a Z-score of 0.29 (61.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 25,003 mm³, 21.8% above the reference mean. With a Z-score of 1.94 (97.4th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 67.0 years. Gender is Female. Education: 19 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Gastrointestinal; Major Surgical Procedures. MMSE: 30.0. MoCA: 26.0. Logical Memory: 19.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.03 SUVR (normal ); Amyloid beta: 1373.00 pg/mL (normal ); Total tau: 139.70 pg/mL (mild reduced); Phosphorylated tau: 11.89 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show normal or above-average volumes in key regions (hippocampus, whole brain, middle temporal gyrus), with no significant atrophy. Biomarkers (Aβ normal, T-tau/P-tau mildly reduced) and normal AV45 PET suggest no amyloid pathology. Cognitive scores (MMSE 30, MoCA 26) are within normal limits, though MoCA is slightly lower than expected for age.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **High**  \n\n*(No evidence of MCI or dementia; preserved brain volumes and normal biomarkers support this conclusion.)*",
  "timestamp": "2025-07-25T23:14:21.717591"
}