{
  "ptid_time": "073_S_2264_2015-02-25",
  "img_path": "/data/qiuhui/data/adni/images/073_S_2264/2015-02-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 64,074 mm³, 66.4% above the reference mean. With a Z-score of 1.59 (94.4th percentile), this represents moderate enlargement; hippocampal volume measures 7,817 mm³, 3.4% above the reference mean. With a Z-score of 0.33 (63.0th percentile), this represents normal volume ; whole brain volume measures 1,155,630 mm³, 7.1% above the reference mean. With a Z-score of 0.92 (82.0th percentile), this represents normal volume ; entorhinal cortex volume measures 4,585 mm³, 11.8% above the reference mean. With a Z-score of 0.80 (78.8th percentile), this represents normal volume ; fusiform gyrus volume measures 18,735 mm³, 0.5% below the reference mean. With a Z-score of -0.05 (48.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,041 mm³, 1.4% below the reference mean. With a Z-score of -0.13 (45.0th percentile), this represents normal volume . ",
  "text_data": "Age is 73.3 years. Gender is Male. Education: 18 years. MMSE: 27.0. MoCA: 23.0. Logical Memory: 14.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.57 SUVR (profound elevated); Amyloid beta: 778.90 pg/mL (normal ); Total tau: 173.90 pg/mL (normal ); Phosphorylated tau: 16.61 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is moderately enlarged (66.4% above reference mean, Z-score 1.59), which can indicate atrophy, but other key brain regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges. The MMSE (27) is borderline normal, while the MoCA (23) suggests mild cognitive impairment. Biomarkers show normal Aβ, T-tau, and P-tau, but AV45 (amyloid PET) is profoundly elevated, indicating significant amyloid deposition despite normal CSF markers.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarker findings—normal CSF but elevated AV45—and borderline cognitive scores)",
  "timestamp": "2025-07-26T09:40:14.459382"
}