{
  "ptid_time": "024_S_4674_2012-04-20",
  "img_path": "/data/qiuhui/data/adni/images/024_S_4674/2012-04-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 20,600 mm³, 46.5% below the reference mean. With a Z-score of -1.11 (13.3th percentile), this represents mild atrophy; hippocampal volume measures 8,542 mm³, 13.0% above the reference mean. With a Z-score of 1.27 (89.8th percentile), this represents mild enlargement; whole brain volume measures 1,155,640 mm³, 7.1% above the reference mean. With a Z-score of 0.92 (82.0th percentile), this represents normal volume ; entorhinal cortex volume measures 4,059 mm³, 1.0% below the reference mean. With a Z-score of -0.07 (47.3th percentile), this represents normal volume ; fusiform gyrus volume measures 21,714 mm³, 15.3% above the reference mean. With a Z-score of 1.30 (90.3th percentile), this represents mild enlargement; middle temporal gyrus volume measures 22,817 mm³, 6.9% above the reference mean. With a Z-score of 0.62 (73.3th percentile), this represents normal volume . ",
  "text_data": "Age is 77.9 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Gastrointestinal; Renal-Genitourinary; Smoking; Major Surgical Procedures. MMSE: 24.0. MoCA: 26.0. Logical Memory: 11.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.28 SUVR (moderate elevated); Amyloid beta: 843.10 pg/mL (normal ); Total tau: 329.10 pg/mL (mild elevated); Phosphorylated tau: 31.89 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volume data shows mild ventricular atrophy but otherwise normal or mildly enlarged volumes in key regions (hippocampus, fusiform gyrus). Cognitive scores (MMSE 24, MoCA 26) are borderline but not strongly indicative of dementia. Biomarkers show normal Aβ but elevated tau and AV45, suggesting possible tauopathy or non-AD pathology.  \nDiagnosis: MCI  \nConfidence: Medium  \n\n(Confidence is medium due to conflicting biomarkers—tau elevation with normal Aβ is atypical for AD, and cognitive scores are near-normal despite imaging/biomarker abnormalities.)",
  "timestamp": "2025-07-26T03:21:22.882281"
}