{
  "ptid_time": "011_S_0003_2007-09-12",
  "img_path": "/data/qiuhui/data/adni/images/011_S_0003/2007-09-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 97,420 mm³, 107.2% above the reference mean. With a Z-score of 3.11 (99.9th percentile), this represents profound enlargement; hippocampal volume measures 5,139 mm³, 26.2% below the reference mean. With a Z-score of -2.27 (1.2th percentile), this represents significant atrophy; whole brain volume measures 1,088,560 mm³, 5.8% above the reference mean. With a Z-score of 0.76 (77.5th percentile), this represents normal volume ; entorhinal cortex volume measures 1,175 mm³, 70.4% below the reference mean. With a Z-score of -4.61 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 14,033 mm³, 22.3% below the reference mean. With a Z-score of -1.93 (2.7th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 16,398 mm³, 18.7% below the reference mean. With a Z-score of -1.68 (4.7th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 83.3 years. Gender is Male. Education: 18 years. MMSE: 19.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement and significant atrophy in the hippocampus, entorhinal cortex, fusiform gyrus, and middle temporal gyrus—key regions affected in Alzheimer's disease. The MMSE score of 19 (indicating moderate cognitive impairment) and the presence of one APOE4 allele further support a neurodegenerative process.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T22:36:59.719085"
}