{
  "ptid_time": "029_S_5219_2015-10-06",
  "img_path": "/data/qiuhui/data/adni/images/029_S_5219/2015-10-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 13,582 mm³, 64.7% below the reference mean. With a Z-score of -1.55 (6.0th percentile), this represents moderate atrophy; hippocampal volume measures 7,517 mm³, 0.6% below the reference mean. With a Z-score of -0.05 (47.8th percentile), this represents normal volume ; whole brain volume measures 1,152,010 mm³, 6.7% above the reference mean. With a Z-score of 0.87 (80.9th percentile), this represents normal volume ; entorhinal cortex volume measures 4,278 mm³, 4.3% above the reference mean. With a Z-score of 0.29 (61.5th percentile), this represents normal volume ; fusiform gyrus volume measures 19,649 mm³, 4.3% above the reference mean. With a Z-score of 0.37 (64.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,018 mm³, 3.2% above the reference mean. With a Z-score of 0.29 (61.3th percentile), this represents normal volume . ",
  "text_data": "Age is 77.7 years. Gender is Male. Education: 16 years. MMSE: 25.0. MoCA: 22.0. Logical Memory: 5.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.05 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume shows moderate atrophy (Z-score -1.55), but hippocampal and other key regional volumes (entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges. Cognitive scores (MMSE 25, MoCA 22) suggest mild impairment, but not severe enough for dementia. APOE4 carrier status and age increase Alzheimer’s risk, but amyloid PET (AV45) is normal, reducing likelihood of AD pathology.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Cognitive decline is present, but structural and amyloid findings do not strongly support dementia or typical AD progression.)",
  "timestamp": "2025-07-26T04:33:16.655405"
}