{
  "ptid_time": "073_S_4382_2011-11-15",
  "img_path": "/data/qiuhui/data/adni/images/073_S_4382/2011-11-15/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 18,072 mm³, 35.6% below the reference mean. With a Z-score of -0.82 (20.7th percentile), this represents normal volume ; hippocampal volume measures 7,240 mm³, 1.8% above the reference mean. With a Z-score of 0.16 (56.4th percentile), this represents normal volume ; whole brain volume measures 892,018 mm³, 8.5% below the reference mean. With a Z-score of -1.07 (14.3th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,801 mm³, 23.7% below the reference mean. With a Z-score of -1.46 (7.3th percentile), this represents mild atrophy; fusiform gyrus volume measures 14,507 mm³, 14.7% below the reference mean. With a Z-score of -1.34 (9.0th percentile), this represents mild atrophy; middle temporal gyrus volume measures 17,374 mm³, 9.4% below the reference mean. With a Z-score of -0.81 (20.8th percentile), this represents normal volume . ",
  "text_data": "Age is 75.9 years. Gender is Female. Education: 16 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Respiratory; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Allergies or Drug Sensitivities; Smoking; Malignancy; Major Surgical Procedures. MMSE: 28.0. MoCA: 27.0. Logical Memory: 13.0. Laboratory findings: Platelets: 367.00 (significant elevated); Hematocrit: 30.00 (profound reduced); RBC: 3.60 (significant reduced); Hemoglobin: 9.80 (profound reduced); Creatine Kinase: 204.00 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.02 SUVR (normal ); Total tau: 357.20 pg/mL (mild elevated); Phosphorylated tau: 32.30 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "Reasoning: The brain imaging shows mild atrophy in the whole brain, entorhinal cortex, and fusiform gyrus, while hippocampal and ventricular volumes are normal. Cognitive scores (MMSE 28, MoCA 27) are within normal limits, and APOE4 is negative, though CSF biomarkers (T-tau, P-tau) are mildly elevated.  \n\nDiagnosis: **CN (Cognitively Normal)**  \nConfidence: **Medium** (Mild atrophy in key regions and elevated biomarkers suggest early neurodegenerative changes, but cognitive performance remains intact.)",
  "timestamp": "2025-07-26T09:44:29.268342"
}