{
  "ptid_time": "003_S_6014_2018-02-15",
  "img_path": "/data/qiuhui/data/adni/images/003_S_6014/2018-02-15/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 113,546 mm³, 278.2% above the reference mean. With a Z-score of 6.61 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 7,651 mm³, 4.7% below the reference mean. With a Z-score of -0.47 (32.0th percentile), this represents normal volume ; whole brain volume measures 1,289,410 mm³, 13.7% above the reference mean. With a Z-score of 1.93 (97.3th percentile), this represents moderate enlargement; entorhinal cortex volume measures 5,562 mm³, 30.5% above the reference mean. With a Z-score of 2.11 (98.3th percentile), this represents significant enlargement; fusiform gyrus volume measures 23,499 mm³, 18.0% above the reference mean. With a Z-score of 1.50 (93.3th percentile), this represents mild enlargement; middle temporal gyrus volume measures 26,418 mm³, 17.9% above the reference mean. With a Z-score of 1.47 (93.0th percentile), this represents mild enlargement. ",
  "text_data": "Age is 67.1 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. MMSE: 30.0. MoCA: 28.0. Logical Memory: 18.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.08 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 6.61), which is strongly suggestive of neurodegeneration, but hippocampal volume is normal (Z-score -0.47). Cognitive scores (MMSE 30, MoCA 28) are intact, and amyloid PET (AV45) is normal, making Alzheimer’s unlikely. The ventricular enlargement may indicate another neurodegenerative process or non-AD pathology.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (due to conflicting imaging findings despite normal cognition)",
  "timestamp": "2025-07-25T20:59:20.199457"
}