{
  "ptid_time": "033_S_0511_2008-06-04",
  "img_path": "/data/qiuhui/data/adni/images/033_S_0511/2008-06-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,874 mm³, 79.4% above the reference mean. With a Z-score of 1.05 (85.4th percentile), this represents mild enlargement; hippocampal volume measures 5,739 mm³.; whole brain volume measures 1,005,240 mm³, 15.7% below the reference mean. With a Z-score of -2.90 (0.2th percentile), this represents significant atrophy; entorhinal cortex volume measures 3,138 mm³, 21.6% below the reference mean. With a Z-score of -1.90 (2.9th percentile), this represents moderate atrophy; fusiform gyrus volume measures 13,299 mm³, 36.2% below the reference mean. With a Z-score of -5.50 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 13,234 mm³.. ",
  "text_data": "Age is 59.7 years. Gender is Male. Education: 14 years. MMSE: 23.0. Logical Memory: 0.0. Laboratory findings: Basophils: 0.13 (profound elevated); Basophils: 1.80 (profound elevated); LDH: 87.00 (profound reduced); Creatinine (Rate Blanked): 2.20 (profound elevated); Urea Nitrogen: 35.00 (profound elevated); Serum Uric Acid: 9.10 (significant elevated). APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in whole brain volume (Z-score -2.90), profound atrophy in the fusiform gyrus (Z-score -5.50), and moderate atrophy in the entorhinal cortex (Z-score -1.90), all of which are strongly associated with neurodegenerative disease. The MMSE score of 23 suggests cognitive impairment, and the absence of APOE4 does not rule out dementia given the structural changes.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given the hippocampal and entorhinal atrophy, though other neurodegenerative etiologies should be considered).  \n\n**Confidence:** **High** (due to the severity of atrophy in key AD-vulnerable regions and cognitive decline).",
  "timestamp": "2025-07-26T05:10:17.210224"
}