{
  "ptid_time": "168_S_6371_2020-10-22",
  "img_path": "/data/qiuhui/data/adni/images/168_S_6371/2020-10-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 37,362 mm³, 24.4% above the reference mean. With a Z-score of 0.58 (71.9th percentile), this represents normal volume ; hippocampal volume measures 7,683 mm³, 4.3% below the reference mean. With a Z-score of -0.43 (33.4th percentile), this represents normal volume ; whole brain volume measures 1,033,450 mm³, 8.9% below the reference mean. With a Z-score of -1.26 (10.4th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,384 mm³, 2.8% above the reference mean. With a Z-score of 0.20 (57.8th percentile), this represents normal volume ; fusiform gyrus volume measures 19,310 mm³, 3.0% below the reference mean. With a Z-score of -0.25 (40.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,959 mm³, 15.4% below the reference mean. With a Z-score of -1.27 (10.2th percentile), this represents mild atrophy. ",
  "text_data": "Age is 69.2 years. Gender is Male. Education: 14 years. MMSE: 24.0. MoCA: 20.0. Logical Memory: 8.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.03 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows mild atrophy in whole brain volume and middle temporal gyrus, with otherwise normal hippocampal and entorhinal cortex volumes. Cognitive testing (MMSE 24, MoCA 20) suggests mild cognitive impairment, but no significant biomarker evidence (normal AV45, no APOE4) strongly supports Alzheimer’s pathology.  \n\n**Diagnosis:** **MCI** (Mild Cognitive Impairment)  \n**Confidence:** **Medium** (due to mixed imaging findings and cognitive scores, but lack of clear biomarker support for dementia)",
  "timestamp": "2025-07-26T17:20:38.106359"
}