{
  "ptid_time": "023_S_4034_2012-07-26",
  "img_path": "/data/qiuhui/data/adni/images/023_S_4034/2012-07-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,158 mm³, 11.0% above the reference mean. With a Z-score of 0.25 (60.0th percentile), this represents normal volume ; hippocampal volume measures 4,608 mm³, 35.2% below the reference mean. With a Z-score of -3.23 (0.1th percentile), this represents profound atrophy; whole brain volume measures 906,879 mm³, 7.0% below the reference mean. With a Z-score of -0.88 (19.1th percentile), this represents normal volume ; entorhinal cortex volume measures 2,461 mm³, 33.0% below the reference mean. With a Z-score of -2.03 (2.1th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,385 mm³, 15.4% below the reference mean. With a Z-score of -1.41 (8.0th percentile), this represents mild atrophy; middle temporal gyrus volume measures 15,681 mm³, 18.2% below the reference mean. With a Z-score of -1.58 (5.7th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 73.1 years. Gender is Female. Education: 19 years. MMSE: 24.0. MoCA: 20.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.23) and significant entorhinal cortex atrophy (Z-score -2.03), both strongly associated with Alzheimer's pathology. The MMSE (24) and MoCA (20) scores indicate cognitive impairment, and the presence of two APOE4 alleles increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T03:01:04.652340"
}