{
  "ptid_time": "023_S_0625_2009-10-20",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0625/2009-10-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 162,729 mm³, 322.5% above the reference mean. With a Z-score of 7.73 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,248 mm³, 17.3% below the reference mean. With a Z-score of -1.69 (4.5th percentile), this represents moderate atrophy; whole brain volume measures 1,158,220 mm³, 7.3% above the reference mean. With a Z-score of 0.95 (82.8th percentile), this represents normal volume ; entorhinal cortex volume measures 3,464 mm³, 15.5% below the reference mean. With a Z-score of -1.05 (14.6th percentile), this represents mild atrophy; fusiform gyrus volume measures 15,885 mm³, 15.7% below the reference mean. With a Z-score of -1.34 (9.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 18,371 mm³, 13.9% below the reference mean. With a Z-score of -1.25 (10.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 78.9 years. Gender is Male. Education: 6 years. MMSE: 15.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (322.5% above mean, Z=7.73) and moderate hippocampal atrophy (17.3% below mean, Z=-1.69), along with mild atrophy in the entorhinal cortex, fusiform gyrus, and middle temporal gyrus. The MMSE score of 15 indicates significant cognitive impairment, consistent with dementia. The absence of APOE4 does not rule out Alzheimer's given the structural deficits.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease given hippocampal and temporal lobe atrophy)  \n**Confidence:** High",
  "timestamp": "2025-07-26T02:46:35.141762"
}