{
  "ptid_time": "023_S_0376_2007-03-20",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0376/2007-03-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 63,535 mm³, 65.0% above the reference mean. With a Z-score of 1.56 (94.0th percentile), this represents moderate enlargement; hippocampal volume measures 7,157 mm³, 5.3% below the reference mean. With a Z-score of -0.52 (30.2th percentile), this represents normal volume ; whole brain volume measures 996,324 mm³, 7.7% below the reference mean. With a Z-score of -1.00 (15.9th percentile), this represents normal volume ; entorhinal cortex volume measures 4,172 mm³, 1.7% above the reference mean. With a Z-score of 0.12 (54.7th percentile), this represents normal volume ; fusiform gyrus volume measures 17,609 mm³, 6.5% below the reference mean. With a Z-score of -0.56 (28.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,406 mm³, 13.7% below the reference mean. With a Z-score of -1.24 (10.8th percentile), this represents mild atrophy. ",
  "text_data": "Age is 71.5 years. Gender is Male. Education: 15 years. MMSE: 27.0. Logical Memory: 5.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1344.00 pg/mL (normal ); Total tau: 158.50 pg/mL (mild reduced); Phosphorylated tau: 12.45 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular enlargement and mild atrophy in the middle temporal gyrus, but hippocampal and other regional volumes are within normal ranges. Cognitive testing (MMSE 27) is normal, and biomarkers (Aβ normal, reduced tau) do not strongly suggest Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mild structural changes but normal cognition and biomarkers)",
  "timestamp": "2025-07-26T02:41:51.087689"
}