{
  "ptid_time": "009_S_2381_2015-05-28",
  "img_path": "/data/qiuhui/data/adni/images/009_S_2381/2015-05-28/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 4,594 mm³, 39.2% below the reference mean. With a Z-score of -3.83 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,117,800 mm³, 3.6% above the reference mean. With a Z-score of 0.46 (67.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,867 mm³, 30.1% below the reference mean. With a Z-score of -2.04 (2.1th percentile), this represents significant atrophy; fusiform gyrus volume measures 20,946 mm³, 11.2% above the reference mean. With a Z-score of 0.95 (83.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,104 mm³, 1.1% below the reference mean. With a Z-score of -0.10 (46.1th percentile), this represents normal volume . ",
  "text_data": "Age is 73.1 years. Gender is Male. Education: 16 years. MMSE: 26.0. MoCA: 24.0. Logical Memory: 13.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.46 SUVR (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.83, 0.0th percentile) and significant entorhinal cortex atrophy (Z-score -2.04, 2.1st percentile), both strongly associated with Alzheimer's pathology. Despite relatively preserved whole brain and other regional volumes, the presence of APOE4 homozygosity and elevated amyloid (AV45) further supports Alzheimer's disease. The MMSE (26) and MoCA (24) scores indicate mild cognitive impairment rather than severe dementia.  \n\n**Diagnosis:** **MCI (likely due to Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T22:17:50.207513"
}