{
  "ptid_time": "011_S_4912_2013-09-13",
  "img_path": "/data/qiuhui/data/adni/images/011_S_4912/2013-09-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 38,993 mm³, 38.9% above the reference mean. With a Z-score of 0.89 (81.4th percentile), this represents normal volume ; hippocampal volume measures 4,619 mm³, 35.1% below the reference mean. With a Z-score of -3.22 (0.1th percentile), this represents profound atrophy; whole brain volume measures 1,061,210 mm³, 8.9% above the reference mean. With a Z-score of 1.12 (86.8th percentile), this represents mild enlargement; entorhinal cortex volume measures 2,863 mm³, 22.1% below the reference mean. With a Z-score of -1.35 (8.8th percentile), this represents mild atrophy; fusiform gyrus volume measures 19,606 mm³, 15.2% above the reference mean. With a Z-score of 1.39 (91.7th percentile), this represents mild enlargement; middle temporal gyrus volume measures 20,538 mm³, 7.1% above the reference mean. With a Z-score of 0.62 (73.2th percentile), this represents normal volume . ",
  "text_data": "Age is 70.2 years. Gender is Female. Education: 18 years. MMSE: 20.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows profound atrophy (Z-score -3.22, 0.1th percentile), which is strongly associated with Alzheimer's disease. The entorhinal cortex also shows mild atrophy, another key region affected in AD. The MMSE score of 20 indicates cognitive impairment, and the presence of two APOE4 alleles further increases AD risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T23:02:21.826525"
}