{
  "ptid_time": "012_S_0689_2006-07-05",
  "img_path": "/data/qiuhui/data/adni/images/012_S_0689/2006-07-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,010 mm³, 53.2% above the reference mean. With a Z-score of 1.26 (89.7th percentile), this represents mild enlargement; hippocampal volume measures 5,225 mm³, 34.9% below the reference mean. With a Z-score of -3.49 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,158,200 mm³, 2.1% above the reference mean. With a Z-score of 0.30 (61.6th percentile), this represents normal volume ; entorhinal cortex volume measures 3,025 mm³, 29.0% below the reference mean. With a Z-score of -2.01 (2.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 13,532 mm³, 32.0% below the reference mean. With a Z-score of -2.66 (0.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 23,050 mm³, 2.8% above the reference mean. With a Z-score of 0.23 (59.3th percentile), this represents normal volume . ",
  "text_data": "Age is 63.6 years. Gender is Male. Education: 12 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Hepatic; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 22.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.49, 0.0th percentile) and significant atrophy in the entorhinal cortex (Z-score -2.01) and fusiform gyrus (Z-score -2.66), which are key regions affected in Alzheimer's disease. The MMSE score of 22 indicates cognitive impairment, and the presence of two APOE4 alleles further increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T23:05:21.951309"
}