{
  "ptid_time": "033_S_0724_2006-07-26",
  "img_path": "/data/qiuhui/data/adni/images/033_S_0724/2006-07-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 106,054 mm³, 175.3% above the reference mean. With a Z-score of 4.20 (100.0th percentile), this represents profound enlargement; whole brain volume measures 999,501 mm³, 7.4% below the reference mean. With a Z-score of -0.96 (16.8th percentile), this represents normal volume . ",
  "text_data": "Age is 78.6 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 21.0. Logical Memory: 5.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 812.70 pg/mL (normal ); Total tau: 455.30 pg/mL (significant elevated); Phosphorylated tau: 42.12 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 4.20) with normal whole brain volume (Z-score -0.96), suggesting significant atrophy. Elevated T-tau and P-tau with normal Aβ indicate tau pathology, while the MMSE of 21 suggests cognitive impairment.  \n\n**Diagnosis:** **Dementia** (likely non-Alzheimer’s tauopathy, such as primary age-related tauopathy [PART] or another tau-related dementia)  \n\n**Confidence:** **Medium** (high confidence in neurodegeneration, but the specific dementia subtype is less certain without additional clinical correlation).",
  "timestamp": "2025-07-26T05:14:26.222166"
}