{
  "ptid_time": "051_S_1131_2007-07-16",
  "img_path": "/data/qiuhui/data/adni/images/051_S_1131/2007-07-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 106,187 mm³, 125.9% above the reference mean. With a Z-score of 3.66 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 7,834 mm³, 12.4% above the reference mean. With a Z-score of 1.07 (85.9th percentile), this represents mild enlargement; whole brain volume measures 1,090,810 mm³, 6.0% above the reference mean. With a Z-score of 0.78 (78.4th percentile), this represents normal volume ; entorhinal cortex volume measures 3,514 mm³, 11.5% below the reference mean. With a Z-score of -0.75 (22.6th percentile), this represents normal volume ; fusiform gyrus volume measures 20,223 mm³, 11.9% above the reference mean. With a Z-score of 1.03 (84.9th percentile), this represents mild enlargement; middle temporal gyrus volume measures 23,425 mm³, 16.1% above the reference mean. With a Z-score of 1.45 (92.6th percentile), this represents mild enlargement. ",
  "text_data": "Age is 86.9 years. Gender is Male. Education: 7 years. MMSE: 28.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.66), which is strongly suggestive of significant brain atrophy, particularly in the context of normal hippocampal volume (Z-score 1.07) and mildly reduced entorhinal cortex volume (Z-score -0.75). The MMSE score of 28 is within the normal range, but ventricular enlargement at this level is atypical for cognitively normal aging and may indicate early neurodegenerative changes despite preserved cognitive scores.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to the discrepancy between structural changes and cognitive performance, and the absence of APOE4 risk allele)",
  "timestamp": "2025-07-26T07:34:05.584471"
}