{
  "ptid_time": "018_S_0286_2006-03-23",
  "img_path": "/data/qiuhui/data/adni/images/018_S_0286/2006-03-23/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 74,313 mm³, 147.5% above the reference mean. With a Z-score of 3.50 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,955 mm³, 13.4% below the reference mean. With a Z-score of -1.33 (9.1th percentile), this represents mild atrophy; whole brain volume measures 1,128,530 mm³, 0.5% below the reference mean. With a Z-score of -0.07 (47.0th percentile), this represents normal volume ; entorhinal cortex volume measures 3,531 mm³, 17.2% below the reference mean. With a Z-score of -1.19 (11.7th percentile), this represents mild atrophy; fusiform gyrus volume measures 19,294 mm³, 3.1% below the reference mean. With a Z-score of -0.26 (39.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,448 mm³, 22.1% below the reference mean. With a Z-score of -1.82 (3.4th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 65.9 years. Gender is Male. Education: 16 years. MMSE: 26.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 642.90 pg/mL (mild reduced); Total tau: 416.90 pg/mL (significant elevated); Phosphorylated tau: 40.28 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (147.5% above mean, Z=3.50) and mild-to-moderate atrophy in key Alzheimer’s-related regions (hippocampus, entorhinal cortex, middle temporal gyrus). Biomarkers (elevated T-tau/P-tau, mildly reduced Aβ) suggest Alzheimer’s pathology, while MMSE (26) indicates mild cognitive impairment.  \n**Diagnosis:** **MCI (likely due to Alzheimer’s disease)**  \n**Confidence:** **High**  \n\n*(Rationale: Structural atrophy + biomarker profile strongly aligns with early AD, but preserved MMSE and absence of functional decline rules out dementia.)*",
  "timestamp": "2025-07-26T00:46:21.779076"
}