{
  "ptid_time": "072_S_4226_2012-10-12",
  "img_path": "/data/qiuhui/data/adni/images/072_S_4226/2012-10-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 5,781 mm³, 74.1% below the reference mean. With a Z-score of -1.85 (3.2th percentile), this represents moderate atrophy; hippocampal volume measures 7,704 mm³, 0.3% above the reference mean. With a Z-score of 0.03 (51.1th percentile), this represents normal volume ; whole brain volume measures 932,405 mm³, 9.4% below the reference mean. With a Z-score of -1.17 (12.1th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,103 mm³, 5.4% above the reference mean. With a Z-score of 0.42 (66.2th percentile), this represents normal volume ; fusiform gyrus volume measures 13,819 mm³, 24.1% below the reference mean. With a Z-score of -2.72 (0.3th percentile), this represents significant atrophy; middle temporal gyrus volume measures 20,222 mm³, 1.5% below the reference mean. With a Z-score of -0.13 (44.9th percentile), this represents normal volume . ",
  "text_data": "Age is 63.9 years. Gender is Female. Education: 17 years. MMSE: 29.0. MoCA: 25.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging shows moderate ventricular enlargement and significant fusiform gyrus atrophy, which are concerning for neurodegenerative changes, while hippocampal and entorhinal volumes are preserved. Cognitive testing (MMSE 29, MoCA 25) suggests mild cognitive impairment (MCI), but the absence of APOE4 reduces Alzheimer's risk.  \n**Diagnosis:** **MCI** (likely non-amnestic given preserved hippocampal volume)  \n**Confidence:** **Medium** (imaging supports neurodegeneration, but clinical profile is not strongly typical of AD)",
  "timestamp": "2025-07-26T09:19:27.963470"
}