{
  "ptid_time": "126_S_4686_2012-11-06",
  "img_path": "/data/qiuhui/data/adni/images/126_S_4686/2012-11-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 45,759 mm³, 18.8% above the reference mean. With a Z-score of 0.45 (67.4th percentile), this represents normal volume ; hippocampal volume measures 5,059 mm³, 33.1% below the reference mean. With a Z-score of -3.23 (0.1th percentile), this represents profound atrophy; whole brain volume measures 1,031,410 mm³, 4.4% below the reference mean. With a Z-score of -0.58 (28.2th percentile), this represents normal volume ; entorhinal cortex volume measures 3,013 mm³, 26.5% below the reference mean. With a Z-score of -1.80 (3.6th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,850 mm³, 0.1% above the reference mean. With a Z-score of 0.01 (50.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,899 mm³, 16.1% below the reference mean. With a Z-score of -1.45 (7.4th percentile), this represents mild atrophy. ",
  "text_data": "Age is 72.2 years. Gender is Male. Education: 12 years. MMSE: 27.0. MoCA: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.23) and moderate entorhinal cortex atrophy (Z-score -1.80), both key regions in Alzheimer's pathology. Despite normal MMSE (27), the MoCA (23) suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T12:49:07.683454"
}