{
  "ptid_time": "021_S_0231_2006-02-28",
  "img_path": "/data/qiuhui/data/adni/images/021_S_0231/2006-02-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 28,981 mm³, 3.5% below the reference mean. With a Z-score of -0.08 (46.7th percentile), this represents normal volume ; hippocampal volume measures 8,124 mm³, 1.2% above the reference mean. With a Z-score of 0.12 (54.8th percentile), this represents normal volume ; whole brain volume measures 1,078,260 mm³, 5.0% below the reference mean. With a Z-score of -0.70 (24.1th percentile), this represents normal volume ; entorhinal cortex volume measures 4,275 mm³, 0.3% above the reference mean. With a Z-score of 0.02 (50.8th percentile), this represents normal volume ; fusiform gyrus volume measures 18,704 mm³, 6.1% below the reference mean. With a Z-score of -0.50 (30.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,817 mm³, 7.1% below the reference mean. With a Z-score of -0.59 (27.9th percentile), this represents normal volume . ",
  "text_data": "Age is 60.3 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Endocrine-Metabolic; Gastrointestinal; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 29.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 426.10 pg/mL (moderate reduced); Total tau: 318.40 pg/mL (normal ); Phosphorylated tau: 31.15 pg/mL (mild elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volumes (ventricular, hippocampal, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) are all within normal ranges based on Z-scores and percentiles. The MMSE score of 29 is normal, and while Aβ is moderately reduced and P-tau is mildly elevated, these biomarkers alone do not strongly indicate neurodegeneration in the absence of significant structural or cognitive deficits.  \nDiagnosis: CN (Cognitively Normal)  \nConfidence: Medium (due to conflicting biomarkers—moderately reduced Aβ and mildly elevated P-tau—but normal imaging and cognition)",
  "timestamp": "2025-07-26T01:22:43.402068"
}