{
  "ptid_time": "002_S_4251_2011-09-26",
  "img_path": "/data/qiuhui/data/adni/images/002_S_4251/2011-09-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,398 mm³, 41.8% below the reference mean. With a Z-score of -1.00 (15.8th percentile), this represents mild atrophy; hippocampal volume measures 7,774 mm³, 2.8% above the reference mean. With a Z-score of 0.28 (60.9th percentile), this represents normal volume ; whole brain volume measures 1,066,460 mm³, 1.2% below the reference mean. With a Z-score of -0.16 (43.8th percentile), this represents normal volume ; entorhinal cortex volume measures 3,368 mm³, 17.9% below the reference mean. With a Z-score of -1.21 (11.3th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,774 mm³, 5.7% below the reference mean. With a Z-score of -0.48 (31.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,659 mm³, 3.2% below the reference mean. With a Z-score of -0.29 (38.7th percentile), this represents normal volume . ",
  "text_data": "Age is 71.9 years. Gender is Male. Education: 19 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities. MMSE: 30.0. MoCA: 23.0. Logical Memory: 8.0. Laboratory findings: Monocytes: 1.06 (profound elevated); Basophils: 0.15 (profound elevated); Monocytes: 14.10 (profound elevated); Basophils: 2.00 (profound elevated); Triglycerides (GPO): 271.00 (significant elevated); GGT: 50.00 (profound elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.00 SUVR (normal ); Amyloid beta: 728.50 pg/mL (normal ); Total tau: 229.30 pg/mL (normal ); Phosphorylated tau: 21.73 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging shows mild atrophy in the ventricular volume and entorhinal cortex, but hippocampal and whole brain volumes are within normal ranges. The MoCA score of 23 suggests mild cognitive impairment, while biomarkers (Aβ, T-tau, P-tau, AV45) are normal, ruling out Alzheimer's pathology.  \n**Diagnosis:** MCI (likely non-amnestic or non-AD etiology)  \n**Confidence:** Medium (due to normal biomarkers but cognitive decline on MoCA)",
  "timestamp": "2025-07-25T20:25:12.881294"
}