{
  "ptid_time": "002_S_1268_2008-06-02",
  "img_path": "/data/qiuhui/data/adni/images/002_S_1268/2008-06-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 77,306 mm³, 64.4% above the reference mean. With a Z-score of 1.87 (96.9th percentile), this represents moderate enlargement; hippocampal volume measures 6,392 mm³, 8.3% below the reference mean. With a Z-score of -0.71 (23.7th percentile), this represents normal volume ; whole brain volume measures 1,014,000 mm³, 1.5% below the reference mean. With a Z-score of -0.19 (42.3th percentile), this represents normal volume ; entorhinal cortex volume measures 3,959 mm³, 0.3% below the reference mean. With a Z-score of -0.02 (49.3th percentile), this represents normal volume ; fusiform gyrus volume measures 17,830 mm³, 1.3% below the reference mean. With a Z-score of -0.11 (45.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,966 mm³, 3.9% above the reference mean. With a Z-score of 0.35 (63.8th percentile), this represents normal volume . ",
  "text_data": "Age is 83.7 years. Gender is Male. Education: 20 years. MMSE: 29.0. Logical Memory: 4.0. Laboratory findings: Basophils: 0.09 (significant elevated); Total Bilirubin: 1.00 (profound elevated); Creatinine (Rate Blanked): 1.60 (profound elevated). APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 528.00 pg/mL (mild reduced); Total tau: 173.10 pg/mL (normal ); Phosphorylated tau: 15.91 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is moderately enlarged (64.4% above mean, Z-score 1.87), which can indicate atrophy, but hippocampal and other regional volumes are within normal ranges. The MMSE score of 29 is intact, and CSF biomarkers (Aβ mildly reduced, normal tau) suggest minimal Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (ventricular enlargement raises some concern, but other measures and cognition are normal)",
  "timestamp": "2025-07-25T20:15:13.925499"
}