{
  "ptid_time": "094_S_4234_2012-10-18",
  "img_path": "/data/qiuhui/data/adni/images/094_S_4234/2012-10-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 43,867 mm³, 13.9% above the reference mean. With a Z-score of 0.33 (63.0th percentile), this represents normal volume ; hippocampal volume measures 6,556 mm³, 13.3% below the reference mean. With a Z-score of -1.29 (9.8th percentile), this represents mild atrophy; whole brain volume measures 1,068,200 mm³, 1.0% below the reference mean. With a Z-score of -0.13 (44.6th percentile), this represents normal volume . ",
  "text_data": "Age is 71.1 years. Gender is Male. Education: 13 years. MMSE: 28.0. MoCA: 25.0. Logical Memory: 11.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows mild atrophy (Z-score -1.29, 9.8th percentile), which is concerning for early neurodegeneration, while ventricular and whole brain volumes are normal. The MMSE (28/30) is normal, but the MoCA (25/30) suggests mild cognitive impairment, particularly in executive function or memory. The presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Hippocampal atrophy and borderline MoCA support MCI, but MMSE is normal, and no functional decline is reported.)",
  "timestamp": "2025-07-26T10:29:53.143307"
}