{
  "ptid_time": "007_S_1304_2007-04-02",
  "img_path": "/data/qiuhui/data/adni/images/007_S_1304/2007-04-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 38,909 mm³, 38.6% above the reference mean. With a Z-score of 0.88 (81.2th percentile), this represents normal volume ; whole brain volume measures 851,945 mm³, 12.6% below the reference mean. With a Z-score of -1.58 (5.6th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 74.7 years. Gender is Female. Education: 8 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Gastrointestinal; Malignancy; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 338.50 pg/mL (moderate reduced); Total tau: 399.60 pg/mL (significant elevated); Phosphorylated tau: 44.82 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows moderate whole brain atrophy (Z-score -1.58) with elevated tau biomarkers (T-tau and P-tau) and moderately reduced Aβ, consistent with Alzheimer's pathology. The MMSE score of 25 suggests mild cognitive impairment, not yet severe enough for dementia.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment, likely due to Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T21:55:06.022992"
}