{
  "ptid_time": "072_S_4131_2012-02-08",
  "img_path": "/data/qiuhui/data/adni/images/072_S_4131/2012-02-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 42,125 mm³, 10.4% below the reference mean. With a Z-score of -0.30 (38.1th percentile), this represents normal volume ; hippocampal volume measures 4,578 mm³, 34.3% below the reference mean. With a Z-score of -2.96 (0.2th percentile), this represents significant atrophy; whole brain volume measures 1,004,130 mm³, 2.4% below the reference mean. With a Z-score of -0.32 (37.5th percentile), this represents normal volume ; entorhinal cortex volume measures 2,606 mm³, 34.3% below the reference mean. With a Z-score of -2.25 (1.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,770 mm³, 12.7% below the reference mean. With a Z-score of -1.10 (13.6th percentile), this represents mild atrophy; middle temporal gyrus volume measures 15,307 mm³, 24.1% below the reference mean. With a Z-score of -2.16 (1.5th percentile), this represents significant atrophy. ",
  "text_data": "Age is 82.9 years. Gender is Male. Education: 18 years. MMSE: 25.0. MoCA: 17.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The data shows significant atrophy in the hippocampus, entorhinal cortex, and middle temporal gyrus—key regions affected in Alzheimer's disease. The cognitive scores (MMSE 25, MoCA 17) indicate mild cognitive impairment, with MoCA being notably low, suggesting deficits in multiple domains. The presence of one APOE4 allele further supports increased Alzheimer's risk.  \nDiagnosis: **Dementia** (likely Alzheimer's type)  \nConfidence: **High**",
  "timestamp": "2025-07-26T09:18:09.514625"
}