{
  "ptid_time": "073_S_4777_2012-12-12",
  "img_path": "/data/qiuhui/data/adni/images/073_S_4777/2012-12-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 47,886 mm³, 29.5% above the reference mean. With a Z-score of 0.80 (78.7th percentile), this represents normal volume ; hippocampal volume measures 5,348 mm³, 17.7% below the reference mean. With a Z-score of -1.42 (7.9th percentile), this represents mild atrophy; whole brain volume measures 883,138 mm³, 4.9% below the reference mean. With a Z-score of -0.58 (28.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,919 mm³, 15.7% below the reference mean. With a Z-score of -0.85 (19.8th percentile), this represents normal volume ; fusiform gyrus volume measures 14,677 mm³, 8.9% below the reference mean. With a Z-score of -0.67 (25.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,655 mm³, 3.5% above the reference mean. With a Z-score of 0.31 (62.1th percentile), this represents normal volume . ",
  "text_data": "Age is 85.2 years. Gender is Female. Education: 14 years. MMSE: 29.0. MoCA: 23.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows mild atrophy (Z-score -1.42, 7.9th percentile), which is a key biomarker for Alzheimer's pathology, while other brain regions remain within normal ranges. The MoCA score of 23 suggests mild cognitive impairment, whereas the MMSE of 29 is borderline normal, indicating possible early cognitive decline. The absence of APOE4 reduces genetic risk but does not rule out neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to hippocampal atrophy and MoCA score, but MMSE is near-normal and no APOE4 risk)",
  "timestamp": "2025-07-26T09:52:30.091111"
}