{
  "ptid_time": "126_S_4494_2014-02-10",
  "img_path": "/data/qiuhui/data/adni/images/126_S_4494/2014-02-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 38,884 mm³, 1.0% above the reference mean. With a Z-score of 0.02 (50.9th percentile), this represents normal volume ; hippocampal volume measures 4,748 mm³, 37.2% below the reference mean. With a Z-score of -3.63 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,054,690 mm³, 2.3% below the reference mean. With a Z-score of -0.30 (38.3th percentile), this represents normal volume ; entorhinal cortex volume measures 1,647 mm³, 59.8% below the reference mean. With a Z-score of -4.06 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 16,033 mm³, 14.9% below the reference mean. With a Z-score of -1.27 (10.2th percentile), this represents mild atrophy; middle temporal gyrus volume measures 22,745 mm³, 6.6% above the reference mean. With a Z-score of 0.59 (72.3th percentile), this represents normal volume . ",
  "text_data": "Age is 73.1 years. Gender is Male. Education: 12 years. MMSE: 21.0. MoCA: 15.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.42 SUVR (significant elevated); Amyloid beta: 300.80 pg/mL (moderate reduced); Total tau: 510.20 pg/mL (profound elevated); Phosphorylated tau: 50.20 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). The cognitive scores (MMSE 21, MoCA 15) indicate significant impairment, and the biomarker profile (elevated Aβ, T-tau, P-tau, and AV45) strongly supports AD pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T12:46:27.556729"
}