{
  "ptid_time": "116_S_0487_2007-06-18",
  "img_path": "/data/qiuhui/data/adni/images/116_S_0487/2007-06-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,546 mm³, 20.8% above the reference mean. With a Z-score of 0.50 (69.1th percentile), this represents normal volume ; hippocampal volume measures 4,575 mm³, 39.5% below the reference mean. With a Z-score of -3.85 (0.0th percentile), this represents profound atrophy; whole brain volume measures 859,937 mm³, 20.3% below the reference mean. With a Z-score of -2.64 (0.4th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,480 mm³, 39.5% below the reference mean. With a Z-score of -2.68 (0.4th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,822 mm³, 21.3% below the reference mean. With a Z-score of -1.82 (3.5th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,713 mm³, 26.4% below the reference mean. With a Z-score of -2.37 (0.9th percentile), this represents significant atrophy. ",
  "text_data": "Age is 77.4 years. Gender is Male. Education: 20 years. MMSE: 19.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows profound hippocampal atrophy (Z-score -3.85, 0th percentile) and significant atrophy in whole brain, entorhinal cortex, and middle temporal gyrus, consistent with Alzheimer’s pathology. The MMSE score of 19 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer’s risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T11:54:57.848033"
}