{
  "ptid_time": "024_S_1307_2009-02-23",
  "img_path": "/data/qiuhui/data/adni/images/024_S_1307/2009-02-23/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,350 mm³, 65.1% above the reference mean. With a Z-score of 1.49 (93.2th percentile), this represents mild enlargement; hippocampal volume measures 6,160 mm³, 13.4% below the reference mean. With a Z-score of -1.23 (10.9th percentile), this represents mild atrophy; whole brain volume measures 999,380 mm³, 2.5% above the reference mean. With a Z-score of 0.32 (62.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,247 mm³, 11.6% below the reference mean. With a Z-score of -0.71 (23.8th percentile), this represents normal volume ; fusiform gyrus volume measures 16,196 mm³, 4.8% below the reference mean. With a Z-score of -0.44 (33.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,494 mm³, 3.5% below the reference mean. With a Z-score of -0.31 (38.0th percentile), this represents normal volume . ",
  "text_data": "Age is 77.3 years. Gender is Female. Education: 13 years. MMSE: 25.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Pittsburgh compound B: 2.33 SUVR (moderate elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild hippocampal atrophy (Z-score -1.23, 10.9th percentile) and mild ventricular enlargement (Z-score 1.49, 93.2nd percentile), which are suggestive of early neurodegenerative changes. The MMSE score of 25 is slightly below normal (typically ≤26 raises concern), and the presence of one APOE4 allele increases Alzheimer's risk. However, other cortical regions (entorhinal, fusiform, middle temporal) are within normal limits, and whole brain volume is preserved.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Findings align with early-stage MCI, but clinical correlation with cognitive symptoms and progression is needed for higher certainty).",
  "timestamp": "2025-07-26T03:14:51.391023"
}