{
  "ptid_time": "013_S_5071_2014-02-11",
  "img_path": "/data/qiuhui/data/adni/images/013_S_5071/2014-02-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 47,169 mm³, 22.5% above the reference mean. With a Z-score of 0.54 (70.5th percentile), this represents normal volume ; hippocampal volume measures 5,963 mm³, 21.1% below the reference mean. With a Z-score of -2.06 (2.0th percentile), this represents significant atrophy; whole brain volume measures 1,054,380 mm³, 2.3% below the reference mean. With a Z-score of -0.30 (38.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,893 mm³, 29.4% below the reference mean. With a Z-score of -2.00 (2.3th percentile), this represents moderate atrophy; fusiform gyrus volume measures 14,796 mm³, 21.5% below the reference mean. With a Z-score of -1.83 (3.4th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 16,244 mm³, 23.9% below the reference mean. With a Z-score of -2.15 (1.6th percentile), this represents significant atrophy. ",
  "text_data": "Age is 77.0 years. Gender is Male. Education: 14 years. MMSE: 17.0. MoCA: 14.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus, entorhinal cortex, fusiform gyrus, and middle temporal gyrus—key regions affected in Alzheimer's disease. The cognitive scores (MMSE 17, MoCA 14) are well below normal, indicating severe impairment, and the presence of two APOE4 alleles further supports an Alzheimer's diagnosis.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T23:37:05.340799"
}