{
  "ptid_time": "052_S_0989_2008-06-17",
  "img_path": "/data/qiuhui/data/adni/images/052_S_0989/2008-06-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 32,940 mm³, 47.5% above the reference mean. With a Z-score of 1.19 (88.3th percentile), this represents mild enlargement; hippocampal volume measures 6,628 mm³, 13.7% below the reference mean. With a Z-score of -1.54 (6.1th percentile), this represents moderate atrophy; whole brain volume measures 900,818 mm³, 12.5% below the reference mean. With a Z-score of -1.55 (6.0th percentile), this represents moderate atrophy; entorhinal cortex volume measures 3,218 mm³, 17.3% below the reference mean. With a Z-score of -1.34 (9.0th percentile), this represents mild atrophy; fusiform gyrus volume measures 13,965 mm³, 23.3% below the reference mean. With a Z-score of -2.63 (0.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 19,639 mm³, 4.3% below the reference mean. With a Z-score of -0.38 (35.1th percentile), this represents normal volume . ",
  "text_data": "Age is 65.8 years. Gender is Female. Education: 13 years. MMSE: 24.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus) alongside mild ventricular enlargement, consistent with neurodegenerative changes. The MMSE score of 24 suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely prodromal Alzheimer's disease)  \n**Confidence:** **High** (due to clear structural atrophy and borderline MMSE, though CSF/biomarkers could further confirm)",
  "timestamp": "2025-07-26T07:42:26.708357"
}