{
  "ptid_time": "135_S_4446_2016-02-18",
  "img_path": "/data/qiuhui/data/adni/images/135_S_4446/2016-02-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 17,803 mm³, 36.6% below the reference mean. With a Z-score of -0.84 (20.1th percentile), this represents normal volume ; hippocampal volume measures 7,220 mm³, 1.5% above the reference mean. With a Z-score of 0.14 (55.4th percentile), this represents normal volume ; whole brain volume measures 971,901 mm³, 0.3% below the reference mean. With a Z-score of -0.04 (48.6th percentile), this represents normal volume ; entorhinal cortex volume measures 4,441 mm³, 20.9% above the reference mean. With a Z-score of 1.28 (90.0th percentile), this represents mild enlargement; fusiform gyrus volume measures 21,770 mm³, 28.0% above the reference mean. With a Z-score of 2.54 (99.5th percentile), this represents significant enlargement; middle temporal gyrus volume measures 18,223 mm³, 4.9% below the reference mean. With a Z-score of -0.43 (33.4th percentile), this represents normal volume . ",
  "text_data": "Age is 72.4 years. Gender is Female. Education: 15 years. MMSE: 29.0. MoCA: 27.0. Logical Memory: 16.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.96 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** All brain volumes (ventricular, hippocampal, whole brain, middle temporal gyrus) are within normal ranges, with some regions (entorhinal cortex, fusiform gyrus) showing mild to significant enlargement, which is atypical for Alzheimer’s. Cognitive scores (MMSE 29, MoCA 27) are normal, and amyloid PET (AV45) is negative. No APOE4 risk allele is present.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T15:36:26.076145"
}