{
  "ptid_time": "013_S_1186_2015-03-18",
  "img_path": "/data/qiuhui/data/adni/images/013_S_1186/2015-03-18/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 5,703 mm³, 10.5% below the reference mean. With a Z-score of -1.14 (12.7th percentile), this represents mild atrophy. ",
  "text_data": "Age is 91.2 years. Gender is Male. Education: 12 years. MMSE: 24.0. MoCA: 16.0. Logical Memory: 4.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.12 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows mild atrophy (10.5% below mean, Z-score -1.14), which is concerning but not severe. The cognitive scores (MMSE 24, MoCA 16) suggest significant impairment, particularly on the MoCA, which is more sensitive to early cognitive decline. The absence of APOE4 and normal AV45 (amyloid PET) reduces the likelihood of Alzheimer's pathology but does not rule out other forms of dementia.  \n\n**Diagnosis:** **Dementia** (likely non-Alzheimer's etiology, such as vascular or mixed dementia, given age and cognitive scores).  \n\n**Confidence:** **Medium** (cognitive deficits are clear, but the underlying cause is uncertain without further clinical correlation or neuroimaging).",
  "timestamp": "2025-07-25T23:26:49.145434"
}