{
  "ptid_time": "041_S_4051_2012-07-12",
  "img_path": "/data/qiuhui/data/adni/images/041_S_4051/2012-07-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,248 mm³, 20.1% above the reference mean. With a Z-score of 0.48 (68.5th percentile), this represents normal volume ; hippocampal volume measures 8,035 mm³, 6.3% above the reference mean. With a Z-score of 0.61 (73.0th percentile), this represents normal volume ; whole brain volume measures 1,290,810 mm³, 19.6% above the reference mean. With a Z-score of 2.54 (99.4th percentile), this represents significant enlargement; entorhinal cortex volume measures 4,469 mm³, 9.0% above the reference mean. With a Z-score of 0.61 (72.9th percentile), this represents normal volume ; fusiform gyrus volume measures 24,957 mm³, 32.5% above the reference mean. With a Z-score of 2.77 (99.7th percentile), this represents significant enlargement; middle temporal gyrus volume measures 27,541 mm³, 29.1% above the reference mean. With a Z-score of 2.61 (99.6th percentile), this represents significant enlargement. ",
  "text_data": "Age is 71.6 years. Gender is Male. Education: 16 years. MMSE: 29.0. MoCA: 25.0. Logical Memory: 13.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show significant enlargement in whole brain, fusiform gyrus, and middle temporal gyrus, while other regions (hippocampus, entorhinal cortex, ventricles) are within normal ranges. Cognitive scores (MMSE 29, MoCA 25) are borderline for MCI but not dementia, and the absence of APOE4 reduces genetic risk.  \n\n**Diagnosis:** **Cognitively Normal (CN)**  \n**Confidence:** **Medium** (due to borderline MoCA but otherwise normal structural and genetic findings)",
  "timestamp": "2025-07-26T07:11:35.782005"
}