{
  "ptid_time": "094_S_1164_2007-06-28",
  "img_path": "/data/qiuhui/data/adni/images/094_S_1164/2007-06-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 34,748 mm³, 23.8% above the reference mean. With a Z-score of 0.54 (70.7th percentile), this represents normal volume ; hippocampal volume measures 4,260 mm³, 40.1% below the reference mean. With a Z-score of -3.68 (0.0th percentile), this represents profound atrophy; whole brain volume measures 808,340 mm³, 17.1% below the reference mean. With a Z-score of -2.15 (1.6th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,357 mm³, 35.8% below the reference mean. With a Z-score of -2.20 (1.4th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,527 mm³, 8.7% below the reference mean. With a Z-score of -0.79 (21.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 11,446 mm³, 40.3% below the reference mean. With a Z-score of -3.50 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 70.0 years. Gender is Female. Education: 16 years. MMSE: 20.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits profound atrophy in the hippocampus and middle temporal gyrus, along with significant atrophy in the whole brain and entorhinal cortex—key regions affected in Alzheimer's disease. The MMSE score of 20 indicates cognitive impairment, and the absence of APOE4 does not rule out AD, as neurodegeneration patterns strongly suggest pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T10:15:58.861552"
}