{
  "ptid_time": "005_S_0221_2007-03-21",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0221/2007-03-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 67,700 mm³, 125.5% above the reference mean. With a Z-score of 2.98 (99.9th percentile), this represents significant enlargement; whole brain volume measures 999,218 mm³, 11.9% below the reference mean. With a Z-score of -1.69 (4.6th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 68.4 years. Gender is Male. Education: 18 years. MMSE: 21.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Amyloid beta: 407.30 pg/mL (moderate reduced); Total tau: 459.80 pg/mL (significant elevated); Phosphorylated tau: 43.58 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 2.98) and moderate whole brain atrophy (Z-score -1.69), consistent with neurodegeneration. Combined with reduced Aβ, elevated T-tau and P-tau, an MMSE of 21, and APOE4 homozygosity, this strongly suggests Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T21:02:32.921717"
}