{
  "ptid_time": "067_S_6443_2018-06-15",
  "img_path": "/data/qiuhui/data/adni/images/067_S_6443/2018-06-15/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 70,535 mm³, 151.3% above the reference mean. With a Z-score of 3.46 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,944 mm³, 16.4% below the reference mean. With a Z-score of -1.51 (6.6th percentile), this represents moderate atrophy; whole brain volume measures 969,301 mm³, 0.5% below the reference mean. With a Z-score of -0.07 (47.2th percentile), this represents normal volume ; entorhinal cortex volume measures 3,863 mm³, 5.2% above the reference mean. With a Z-score of 0.32 (62.5th percentile), this represents normal volume ; fusiform gyrus volume measures 17,282 mm³, 1.6% above the reference mean. With a Z-score of 0.14 (55.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,470 mm³, 1.6% above the reference mean. With a Z-score of 0.14 (55.4th percentile), this represents normal volume . ",
  "text_data": "Age is 77.5 years. Gender is Female. Education: 18 years. MMSE: 29.0. MoCA: 27.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Flobetaben (FBB): 1.03 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.46) and moderate hippocampal atrophy (Z-score -1.51), both of which are strong neuroimaging markers for Alzheimer's disease. However, cognitive scores (MMSE 29, MoCA 27) are within normal limits, and there is no APOE4 risk allele, suggesting preserved cognitive function despite structural changes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (due to significant structural changes without overt cognitive decline)  \n**Confidence:** **Medium** (cognitive scores are normal, but hippocampal atrophy and ventricular enlargement are concerning for early neurodegeneration)",
  "timestamp": "2025-07-26T08:43:28.379026"
}