{
  "ptid_time": "041_S_1368_2007-03-05",
  "img_path": "/data/qiuhui/data/adni/images/041_S_1368/2007-03-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,748 mm³, 59.4% above the reference mean. With a Z-score of 1.36 (91.3th percentile), this represents mild enlargement; hippocampal volume measures 4,931 mm³, 30.7% below the reference mean. With a Z-score of -2.82 (0.2th percentile), this represents significant atrophy; whole brain volume measures 805,281 mm³, 17.4% below the reference mean. With a Z-score of -2.19 (1.4th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,988 mm³, 45.9% below the reference mean. With a Z-score of -2.82 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,245 mm³, 33.9% below the reference mean. With a Z-score of -3.09 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 10,234 mm³, 46.6% below the reference mean. With a Z-score of -4.05 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 75.2 years. Gender is Female. Education: 18 years. Handedness: Right. Race: White. Medical history: Neurologic; Cardiovascular; Endocrine-Metabolic; Gastrointestinal; Smoking; Major Surgical Procedures. MMSE: 20.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) with Z-scores well below the mean, alongside mild ventricular enlargement. The MMSE score of 20 indicates cognitive impairment, and the absence of APOE4 does not rule out Alzheimer's given the structural deficits.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T07:04:43.549793"
}