{
  "ptid_time": "094_S_0434_2007-11-08",
  "img_path": "/data/qiuhui/data/adni/images/094_S_0434/2007-11-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 37,969 mm³, 1.4% below the reference mean. With a Z-score of -0.03 (48.6th percentile), this represents normal volume ; hippocampal volume measures 5,803 mm³, 23.2% below the reference mean. With a Z-score of -2.27 (1.2th percentile), this represents significant atrophy; whole brain volume measures 947,525 mm³, 12.2% below the reference mean. With a Z-score of -1.59 (5.6th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,895 mm³, 29.4% below the reference mean. With a Z-score of -1.99 (2.3th percentile), this represents moderate atrophy; fusiform gyrus volume measures 16,334 mm³, 13.3% below the reference mean. With a Z-score of -1.13 (12.9th percentile), this represents mild atrophy; middle temporal gyrus volume measures 12,543 mm³, 41.2% below the reference mean. With a Z-score of -3.71 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 73.2 years. Gender is Male. Education: 20 years. MMSE: 27.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus (Z-score -2.27, 1.2th percentile) and profound atrophy in the middle temporal gyrus (Z-score -3.71, 0.0th percentile), both key regions in Alzheimer's pathology. Despite a normal MMSE (27/30), the structural changes suggest neurodegeneration consistent with early Alzheimer’s disease.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer’s pathology)  \n**Confidence:** **Medium** (due to the discrepancy between imaging findings and preserved MMSE, though atrophy patterns strongly suggest progression toward dementia)",
  "timestamp": "2025-07-26T10:11:12.427036"
}