{
  "ptid_time": "094_S_0434_2006-04-20",
  "img_path": "/data/qiuhui/data/adni/images/094_S_0434/2006-04-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 30,268 mm³, 21.4% below the reference mean. With a Z-score of -0.51 (30.4th percentile), this represents normal volume ; hippocampal volume measures 6,629 mm³, 12.3% below the reference mean. With a Z-score of -1.20 (11.5th percentile), this represents mild atrophy; whole brain volume measures 983,321 mm³, 8.9% below the reference mean. With a Z-score of -1.16 (12.4th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,191 mm³, 22.2% below the reference mean. With a Z-score of -1.50 (6.6th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,302 mm³, 2.8% below the reference mean. With a Z-score of -0.24 (40.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 14,656 mm³, 31.3% below the reference mean. With a Z-score of -2.82 (0.2th percentile), this represents significant atrophy. ",
  "text_data": "Age is 71.7 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Hepatic; Dermatologic-Connective Tissue; Renal-Genitourinary; Major Surgical Procedures. MMSE: 26.0. Logical Memory: 2.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the middle temporal gyrus (Z-score -2.82, 0.2nd percentile) and moderate atrophy in the entorhinal cortex (Z-score -1.50, 6.6th percentile), both key regions in Alzheimer's pathology. The MMSE score of 26 is borderline, suggesting mild cognitive impairment, while the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to borderline MMSE and lack of detailed neuropsychological testing to confirm functional decline)",
  "timestamp": "2025-07-26T10:10:50.846457"
}