{
  "ptid_time": "100_S_1286_2014-03-28",
  "img_path": "/data/qiuhui/data/adni/images/100_S_1286/2014-03-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 58,108 mm³, 57.2% above the reference mean. With a Z-score of 1.54 (93.9th percentile), this represents moderate enlargement; hippocampal volume measures 8,276 mm³, 27.4% above the reference mean. With a Z-score of 2.20 (98.6th percentile), this represents significant enlargement; whole brain volume measures 1,073,840 mm³, 15.7% above the reference mean. With a Z-score of 1.88 (97.0th percentile), this represents moderate enlargement; entorhinal cortex volume measures 3,999 mm³, 15.5% above the reference mean. With a Z-score of 0.84 (79.9th percentile), this represents normal volume ; fusiform gyrus volume measures 16,166 mm³, 0.3% above the reference mean. With a Z-score of 0.03 (51.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,723 mm³, 20.5% above the reference mean. With a Z-score of 1.82 (96.6th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 82.5 years. Gender is Female. Education: 19 years. MMSE: 29.0. MoCA: 28.0. Logical Memory: 21.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows significant enlargement in the hippocampus and moderate enlargement in the ventricles, whole brain, and middle temporal gyrus, while other regions are within normal ranges. The high MMSE (29) and MoCA (28) scores indicate intact cognitive function, and the absence of APOE4 reduces genetic risk for Alzheimer’s.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (While the volumetric changes could suggest early neurodegeneration, the strong cognitive performance and lack of APOE4 support a normal diagnosis. However, ventricular enlargement warrants monitoring.)",
  "timestamp": "2025-07-26T11:24:07.488337"
}