{
  "ptid_time": "037_S_1078_2015-03-16",
  "img_path": "/data/qiuhui/data/adni/images/037_S_1078/2015-03-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,031 mm³, 19.4% below the reference mean. With a Z-score of -0.47 (32.1th percentile), this represents normal volume ; hippocampal volume measures 4,987 mm³, 34.0% below the reference mean. With a Z-score of -3.32 (0.0th percentile), this represents profound atrophy; whole brain volume measures 946,145 mm³, 12.3% below the reference mean. With a Z-score of -1.60 (5.5th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,013 mm³, 50.9% below the reference mean. With a Z-score of -3.45 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 17,221 mm³, 8.6% below the reference mean. With a Z-score of -0.73 (23.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,826 mm³, 21.1% below the reference mean. With a Z-score of -1.90 (2.9th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 78.6 years. Gender is Male. Education: 16 years. MMSE: 20.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The patient shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). Moderate atrophy in the whole brain and middle temporal gyrus, along with an MMSE score of 20 (indicating cognitive impairment), further supports a neurodegenerative process. The presence of two APOE4 alleles increases genetic risk for AD.  \n\nDiagnosis: **Dementia (likely Alzheimer’s disease)**  \nConfidence: **High**",
  "timestamp": "2025-07-26T06:36:24.111742"
}