{
  "ptid_time": "133_S_0727_2008-09-30",
  "img_path": "/data/qiuhui/data/adni/images/133_S_0727/2008-09-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 70,437 mm³, 151.0% above the reference mean. With a Z-score of 3.46 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,255 mm³, 26.1% below the reference mean. With a Z-score of -2.40 (0.8th percentile), this represents significant atrophy; whole brain volume measures 985,950 mm³, 1.2% above the reference mean. With a Z-score of 0.15 (55.8th percentile), this represents normal volume ; entorhinal cortex volume measures 1,805 mm³, 50.9% below the reference mean. With a Z-score of -3.12 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 13,132 mm³, 22.8% below the reference mean. With a Z-score of -2.08 (1.9th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,689 mm³, 28.6% below the reference mean. With a Z-score of -2.48 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 71.2 years. Gender is Female. Education: 12 years. MMSE: 19.0. Logical Memory: 7.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (151% above mean, Z-score 3.46) and significant atrophy in key Alzheimer’s-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside cognitive impairment (MMSE 19). The presence of two APOE4 alleles further increases Alzheimer’s risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T15:25:15.479063"
}