{
  "ptid_time": "072_S_4613_2012-04-02",
  "img_path": "/data/qiuhui/data/adni/images/072_S_4613/2012-04-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,037 mm³, 60.0% above the reference mean. With a Z-score of 1.43 (92.3th percentile), this represents mild enlargement; hippocampal volume measures 7,154 mm³, 10.9% below the reference mean. With a Z-score of -1.09 (13.9th percentile), this represents mild atrophy; whole brain volume measures 1,115,850 mm³, 1.6% below the reference mean. With a Z-score of -0.23 (40.8th percentile), this represents normal volume ; entorhinal cortex volume measures 4,999 mm³, 17.3% above the reference mean. With a Z-score of 1.20 (88.4th percentile), this represents mild enlargement; fusiform gyrus volume measures 21,634 mm³, 8.7% above the reference mean. With a Z-score of 0.72 (76.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,097 mm³, 1.4% below the reference mean. With a Z-score of -0.12 (45.4th percentile), this represents normal volume . ",
  "text_data": "Age is 67.8 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Neurologic; Cardiovascular; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 27.0. MoCA: 23.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.98 SUVR (normal ); Amyloid beta: 1428.00 pg/mL (mild elevated); Total tau: 203.90 pg/mL (normal ); Phosphorylated tau: 18.10 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild hippocampal atrophy (Z-score -1.09) and mild ventricular enlargement (Z-score 1.43), which are suggestive of early neurodegenerative changes. The MMSE (27) is within normal limits, but the MoCA (23) suggests mild cognitive impairment, supported by mildly elevated Aβ (though tau markers are normal).  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarkers—hippocampal atrophy and elevated Aβ suggest neurodegeneration, but tau and AV45 are normal, and cognitive scores are borderline).",
  "timestamp": "2025-07-26T09:25:23.745337"
}