{
  "ptid_time": "041_S_1425_2008-02-06",
  "img_path": "/data/qiuhui/data/adni/images/041_S_1425/2008-02-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,158 mm³, 49.6% below the reference mean. With a Z-score of -1.13 (12.8th percentile), this represents mild atrophy; hippocampal volume measures 6,739 mm³, 5.3% below the reference mean. With a Z-score of -0.48 (31.4th percentile), this represents normal volume ; whole brain volume measures 905,339 mm³, 7.1% below the reference mean. With a Z-score of -0.90 (18.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,862 mm³, 5.1% above the reference mean. With a Z-score of 0.32 (62.4th percentile), this represents normal volume ; fusiform gyrus volume measures 14,214 mm³, 16.5% below the reference mean. With a Z-score of -1.50 (6.7th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,958 mm³, 11.5% below the reference mean. With a Z-score of -1.00 (15.8th percentile), this represents mild atrophy. ",
  "text_data": "Age is 76.1 years. Gender is Female. Education: 16 years. MMSE: 26.0. Laboratory findings: Monocytes: 0.64 (significant elevated); Monocytes: 12.40 (profound elevated); Triglycerides (GPO): 290.00 (profound elevated). APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild atrophy in the ventricular volume, fusiform gyrus, and middle temporal gyrus, while hippocampal, whole brain, and entorhinal cortex volumes are within normal ranges. The MMSE score of 26 is slightly below the typical cutoff for normal cognition (≥27), but the absence of significant hippocampal atrophy and APOE4 negativity reduces the likelihood of Alzheimer’s pathology.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to borderline MMSE and mixed atrophy patterns without clear hippocampal involvement)",
  "timestamp": "2025-07-26T07:07:58.944184"
}