{
  "ptid_time": "019_S_4293_2011-10-20",
  "img_path": "/data/qiuhui/data/adni/images/019_S_4293/2011-10-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,742 mm³, 24.3% below the reference mean. With a Z-score of -0.58 (28.2th percentile), this represents normal volume ; hippocampal volume measures 8,545 mm³, 6.5% above the reference mean. With a Z-score of 0.64 (74.1th percentile), this represents normal volume ; whole brain volume measures 1,130,140 mm³, 0.4% below the reference mean. With a Z-score of -0.05 (47.8th percentile), this represents normal volume ; entorhinal cortex volume measures 4,250 mm³, 0.3% below the reference mean. With a Z-score of -0.02 (49.2th percentile), this represents normal volume ; fusiform gyrus volume measures 19,421 mm³, 2.5% below the reference mean. With a Z-score of -0.20 (41.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,670 mm³, 7.8% below the reference mean. With a Z-score of -0.64 (26.1th percentile), this represents normal volume . ",
  "text_data": "Age is 69.7 years. Gender is Male. Education: 12 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 26.0. MoCA: 20.0. Logical Memory: 9.0. Laboratory findings: Monocytes: 0.63 (significant elevated); WBC: 9.97 (significant elevated); Lymphocytes: 3.16 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.99 SUVR (normal ); Total tau: 213.30 pg/mL (normal ); Phosphorylated tau: 18.96 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements (hippocampus, entorhinal cortex, fusiform gyrus, etc.) are all within normal ranges, with no significant atrophy. However, the MoCA score (20/30) suggests mild cognitive impairment, while the MMSE (26/30) is borderline. Biomarkers (T-tau, P-tau, AV45) are normal, and there is no APOE4 risk allele.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to the discrepancy between cognitive testing and normal imaging/biomarkers)",
  "timestamp": "2025-07-26T01:03:58.322187"
}