{
  "ptid_time": "023_S_0061_2006-06-15",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0061/2006-06-15/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 32,239 mm³, 14.9% above the reference mean. With a Z-score of 0.34 (63.3th percentile), this represents normal volume ; hippocampal volume measures 7,004 mm³, 1.6% below the reference mean. With a Z-score of -0.14 (44.3th percentile), this represents normal volume ; whole brain volume measures 929,633 mm³, 4.6% below the reference mean. With a Z-score of -0.58 (28.0th percentile), this represents normal volume ; entorhinal cortex volume measures 5,064 mm³, 37.9% above the reference mean. With a Z-score of 2.32 (99.0th percentile), this represents significant enlargement; fusiform gyrus volume measures 16,575 mm³, 2.6% below the reference mean. With a Z-score of -0.23 (40.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,532 mm³, 13.8% below the reference mean. With a Z-score of -1.19 (11.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 77.5 years. Gender is Female. Education: 15 years. MMSE: 29.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show mostly normal values, with mild atrophy in the middle temporal gyrus and significant enlargement of the entorhinal cortex (which is atypical for Alzheimer's). The MMSE score of 29 is within the normal range, and the absence of APOE4 reduces genetic risk. No significant hippocampal atrophy is present.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to the unusual entorhinal cortex enlargement, which may warrant further investigation despite normal cognitive scores)",
  "timestamp": "2025-07-26T02:31:05.911125"
}