{
  "ptid_time": "094_S_4089_2011-06-29",
  "img_path": "/data/qiuhui/data/adni/images/094_S_4089/2011-06-29/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 5,536 mm³, 26.8% below the reference mean. With a Z-score of -2.61 (0.5th percentile), this represents significant atrophy; whole brain volume measures 1,036,210 mm³, 4.0% below the reference mean. With a Z-score of -0.52 (30.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,580 mm³, 37.1% below the reference mean. With a Z-score of -2.51 (0.6th percentile), this represents significant atrophy; fusiform gyrus volume measures 16,405 mm³, 12.9% below the reference mean. With a Z-score of -1.10 (13.6th percentile), this represents mild atrophy; middle temporal gyrus volume measures 15,329 mm³, 28.2% below the reference mean. With a Z-score of -2.53 (0.6th percentile), this represents significant atrophy. ",
  "text_data": "Age is 73.7 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Respiratory; Musculoskeletal; Alcohol Abuse; Smoking; Major Surgical Procedures. MMSE: 24.0. MoCA: 16.0. Logical Memory: 0.0. Laboratory findings: Eosinophils: 0.33 (significant elevated); Basophils: 0.12 (profound elevated); Basophils: 1.50 (significant elevated); Total Bilirubin: 1.40 (profound elevated); Direct Bilirubin: 0.30 (significant elevated); Serum Uric Acid: 8.50 (significant elevated). APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.52 SUVR (profound elevated); Amyloid beta: 751.80 pg/mL (normal ); Total tau: 564.10 pg/mL (profound elevated); Phosphorylated tau: 57.63 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The patient exhibits significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, middle temporal gyrus) alongside profound elevations in tau and AV45 (amyloid PET), despite normal Aβ levels. Cognitive scores (MMSE 24, MoCA 16) indicate moderate impairment, consistent with neurodegenerative disease. The APOE4 carrier status further supports Alzheimer's pathology.  \nDiagnosis: Dementia (likely Alzheimer’s disease)  \nConfidence: High",
  "timestamp": "2025-07-26T10:28:20.838385"
}