{
  "ptid_time": "009_S_0751_2006-07-25",
  "img_path": "/data/qiuhui/data/adni/images/009_S_0751/2006-07-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 83,481 mm³, 116.7% above the reference mean. With a Z-score of 2.80 (99.7th percentile), this represents significant enlargement; hippocampal volume measures 7,290 mm³, 3.6% below the reference mean. With a Z-score of -0.35 (36.4th percentile), this represents normal volume ; whole brain volume measures 1,006,650 mm³, 6.7% below the reference mean. With a Z-score of -0.87 (19.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,499 mm³, 14.7% below the reference mean. With a Z-score of -0.99 (16.0th percentile), this represents normal volume ; fusiform gyrus volume measures 18,604 mm³, 1.2% below the reference mean. With a Z-score of -0.11 (45.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,652 mm³, 3.2% below the reference mean. With a Z-score of -0.29 (38.6th percentile), this represents normal volume . ",
  "text_data": "Age is 70.9 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Gastrointestinal; Renal-Genitourinary; Major Surgical Procedures. MMSE: 27.0. Logical Memory: 13.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 929.40 pg/mL (normal ); Total tau: 113.20 pg/mL (moderate reduced); Phosphorylated tau: 9.89 pg/mL (moderate reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 2.80), which is often associated with brain atrophy, but hippocampal and other regional volumes are within normal ranges (Z-scores close to 0). The MMSE score of 27 is normal, and biomarkers (Aβ normal, reduced T-tau/P-tau) do not strongly suggest Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (ventricular enlargement is notable, but other markers do not support neurodegeneration or cognitive impairment)",
  "timestamp": "2025-07-25T22:10:25.672393"
}