{
  "ptid_time": "018_S_0406_2007-06-08",
  "img_path": "/data/qiuhui/data/adni/images/018_S_0406/2007-06-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 74,955 mm³, 94.6% above the reference mean. With a Z-score of 2.27 (98.8th percentile), this represents significant enlargement; hippocampal volume measures 4,975 mm³, 34.2% below the reference mean. With a Z-score of -3.33 (0.0th percentile), this represents profound atrophy; whole brain volume measures 880,152 mm³, 18.5% below the reference mean. With a Z-score of -2.40 (0.8th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,198 mm³, 46.4% below the reference mean. With a Z-score of -3.15 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,305 mm³, 40.0% below the reference mean. With a Z-score of -3.41 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 15,318 mm³, 28.2% below the reference mean. With a Z-score of -2.54 (0.6th percentile), this represents significant atrophy. ",
  "text_data": "Age is 78.8 years. Gender is Male. Education: 11 years. MMSE: 26.0. Logical Memory: 2.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus) and significant whole-brain atrophy, alongside severe ventricular enlargement, consistent with advanced neurodegeneration. Despite a relatively preserved MMSE score (26), the structural changes strongly suggest dementia, likely Alzheimer's disease, given the APOE4 carrier status and age.  \n\n**Diagnosis:** Dementia (probable Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T00:49:04.689874"
}