{
  "ptid_time": "135_S_5275_2013-08-05",
  "img_path": "/data/qiuhui/data/adni/images/135_S_5275/2013-08-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,716 mm³, 155.5% above the reference mean. With a Z-score of 3.56 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,843 mm³, 3.8% below the reference mean. With a Z-score of -0.35 (36.3th percentile), this represents normal volume ; whole brain volume measures 1,146,280 mm³, 17.6% above the reference mean. With a Z-score of 2.22 (98.7th percentile), this represents significant enlargement. ",
  "text_data": "Age is 78.0 years. Gender is Female. Education: 12 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Endocrine-Metabolic; Malignancy. MMSE: 24.0. MoCA: 20.0. Logical Memory: 3.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.59 SUVR (profound elevated); Amyloid beta: 832.70 pg/mL (normal ); Total tau: 490.40 pg/mL (profound elevated); Phosphorylated tau: 53.18 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The patient shows profound ventricular enlargement (indicating significant atrophy) and elevated biomarkers (T-tau, P-tau, AV45), which are strongly associated with Alzheimer's pathology. Despite normal hippocampal volume and Aβ levels, the cognitive scores (MMSE 24, MoCA 20) suggest impairment.  \nDiagnosis: Dementia (likely Alzheimer’s disease)  \nConfidence: Medium (due to normal Aβ but elevated tau and imaging/clinical correlation)",
  "timestamp": "2025-07-26T15:48:49.788647"
}