{
  "ptid_time": "153_S_4077_2011-09-20",
  "img_path": "/data/qiuhui/data/adni/images/153_S_4077/2011-09-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 64,325 mm³, 67.0% above the reference mean. With a Z-score of 1.61 (94.6th percentile), this represents moderate enlargement; hippocampal volume measures 6,896 mm³, 8.8% below the reference mean. With a Z-score of -0.86 (19.6th percentile), this represents normal volume ; whole brain volume measures 1,217,980 mm³, 12.8% above the reference mean. With a Z-score of 1.67 (95.2th percentile), this represents moderate enlargement; entorhinal cortex volume measures 3,746 mm³, 8.6% below the reference mean. With a Z-score of -0.59 (27.9th percentile), this represents normal volume ; fusiform gyrus volume measures 21,003 mm³, 11.5% above the reference mean. With a Z-score of 0.98 (83.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,273 mm³, 13.7% above the reference mean. With a Z-score of 1.24 (89.2th percentile), this represents mild enlargement. ",
  "text_data": "Age is 75.4 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Major Surgical Procedures. MMSE: 28.0. MoCA: 25.0. Logical Memory: 7.0. Laboratory findings: Eosinophils: 0.56 (profound elevated); Eosinophils: 7.60 (profound elevated); Calcium (EDTA): 10.90 (significant elevated); Triglycerides (GPO): 240.00 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.98 SUVR (normal ); Amyloid beta: 1395.00 pg/mL (normal ); Total tau: 141.80 pg/mL (mild reduced); Phosphorylated tau: 11.16 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is moderately enlarged (Z-score 1.61), which can indicate atrophy, but hippocampal and entorhinal cortex volumes are within normal limits (Z-scores -0.86 and -0.59, respectively). Cognitive scores (MMSE 28, MoCA 25) are near normal, and biomarkers (Aβ normal, tau reduced) do not strongly suggest Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (ventricular enlargement raises some concern, but other markers are reassuring)",
  "timestamp": "2025-07-26T17:09:59.728562"
}