{
  "ptid_time": "114_S_0458_2007-06-14",
  "img_path": "/data/qiuhui/data/adni/images/114_S_0458/2007-06-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 32,714 mm³, 11.5% below the reference mean. With a Z-score of -0.31 (37.8th percentile), this represents normal volume ; hippocampal volume measures 5,595 mm³, 13.9% below the reference mean. With a Z-score of -1.11 (13.3th percentile), this represents mild atrophy; whole brain volume measures 829,358 mm³, 10.6% below the reference mean. With a Z-score of -1.28 (10.1th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,499 mm³, 1.1% above the reference mean. With a Z-score of 0.06 (52.3th percentile), this represents normal volume ; fusiform gyrus volume measures 13,356 mm³, 17.1% below the reference mean. With a Z-score of -1.28 (9.9th percentile), this represents mild atrophy; middle temporal gyrus volume measures 17,196 mm³, 4.6% below the reference mean. With a Z-score of -0.41 (34.1th percentile), this represents normal volume . ",
  "text_data": "Age is 83.9 years. Gender is Female. Education: 11 years. MMSE: 18.0. Logical Memory: 2.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows mild atrophy in the hippocampus, whole brain, and fusiform gyrus, which are key regions affected in Alzheimer's disease. The MMSE score of 18 indicates significant cognitive impairment, consistent with dementia rather than MCI. The presence of one APOE4 allele further supports increased risk for Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T11:42:10.487669"
}