{
  "ptid_time": "027_S_1387_2007-03-19",
  "img_path": "/data/qiuhui/data/adni/images/027_S_1387/2007-03-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 89,893 mm³, 91.2% above the reference mean. With a Z-score of 2.65 (99.6th percentile), this represents significant enlargement; whole brain volume measures 869,465 mm³, 15.5% below the reference mean. With a Z-score of -2.03 (2.1th percentile), this represents significant atrophy. ",
  "text_data": "Age is 85.6 years. Gender is Male. Education: 20 years. Handedness: Unknown. Race: Unknown. Medical history: Psychiatric; Neurologic; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Major Surgical Procedures. MMSE: 27.0. Logical Memory: 3.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (91.2% above mean, Z-score 2.65) and whole brain atrophy (15.5% below mean, Z-score -2.03), both strongly indicative of neurodegeneration. Despite a relatively preserved MMSE score (27/30), the structural changes and age (85.6) suggest early cognitive decline.  \n**Diagnosis:** **MCI** (mild cognitive impairment)  \n**Confidence:** **Medium** (MMSE is borderline normal, but imaging strongly supports neurodegeneration; APOE4 carrier status increases risk but is not definitive).  \n\n*Note: A follow-up clinical assessment (e.g., neuropsychological testing) would help clarify if this meets dementia criteria (e.g., functional impairment).*",
  "timestamp": "2025-07-26T03:50:42.679380"
}