{
  "ptid_time": "007_S_0249_2006-03-02",
  "img_path": "/data/qiuhui/data/adni/images/007_S_0249/2006-03-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 37,297 mm³, 32.9% above the reference mean. With a Z-score of 0.75 (77.4th percentile), this represents normal volume ; hippocampal volume measures 4,622 mm³, 35.0% below the reference mean. With a Z-score of -3.21 (0.1th percentile), this represents profound atrophy; whole brain volume measures 927,419 mm³, 4.8% below the reference mean. With a Z-score of -0.61 (27.1th percentile), this represents normal volume ; entorhinal cortex volume measures 2,181 mm³, 40.6% below the reference mean. With a Z-score of -2.49 (0.6th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,040 mm³, 17.5% below the reference mean. With a Z-score of -1.59 (5.6th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 16,288 mm³, 15.0% below the reference mean. With a Z-score of -1.30 (9.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 72.0 years. Gender is Female. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 29.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.21) and significant entorhinal cortex atrophy (Z-score -2.49), both strongly associated with Alzheimer's pathology. However, the MMSE score of 29 is within the normal range, suggesting no significant cognitive impairment at present.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment)**  \n**Confidence:** **Medium**  \n\n*(Rationale: Structural atrophy in Alzheimer’s-vulnerable regions is concerning, but the absence of cognitive deficits on MMSE suggests preclinical or very early-stage MCI. APOE4 carrier status increases risk but does not confirm progression.)*",
  "timestamp": "2025-07-25T21:47:25.740751"
}