{
  "ptid_time": "135_S_4657_2012-10-29",
  "img_path": "/data/qiuhui/data/adni/images/135_S_4657/2012-10-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 40,842 mm³, 45.5% above the reference mean. With a Z-score of 1.04 (85.1th percentile), this represents mild enlargement; hippocampal volume measures 4,705 mm³, 33.9% below the reference mean. With a Z-score of -3.11 (0.1th percentile), this represents profound atrophy; whole brain volume measures 924,891 mm³, 5.1% below the reference mean. With a Z-score of -0.64 (26.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,056 mm³, 44.0% below the reference mean. With a Z-score of -2.70 (0.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 10,200 mm³, 40.0% below the reference mean. With a Z-score of -3.64 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 10,686 mm³, 44.3% below the reference mean. With a Z-score of -3.84 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 72.0 years. Gender is Female. Education: 12 years. MMSE: 20.0. MoCA: 12.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside mild ventricular enlargement and normal whole-brain volume. The cognitive scores (MMSE 20, MoCA 12) indicate significant impairment, and the presence of one APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T15:39:35.648600"
}