{
  "ptid_time": "005_S_0448_2007-07-13",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0448/2007-07-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,038 mm³, 51.1% above the reference mean. With a Z-score of 1.48 (93.1th percentile), this represents mild enlargement; hippocampal volume measures 6,126 mm³, 12.1% below the reference mean. With a Z-score of -1.04 (14.8th percentile), this represents mild atrophy; whole brain volume measures 1,063,300 mm³, 3.3% above the reference mean. With a Z-score of 0.43 (66.8th percentile), this represents normal volume ; entorhinal cortex volume measures 4,303 mm³, 8.4% above the reference mean. With a Z-score of 0.55 (70.9th percentile), this represents normal volume ; fusiform gyrus volume measures 18,495 mm³, 2.4% above the reference mean. With a Z-score of 0.21 (58.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,345 mm³, 0.9% above the reference mean. With a Z-score of 0.08 (53.1th percentile), this represents normal volume . ",
  "text_data": "Age is 86.5 years. Gender is Male. Education: 17 years. Handedness: Unknown. Race: Unknown. MMSE: 28.0. Logical Memory: 7.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1447.00 pg/mL (mild elevated); Total tau: 216.50 pg/mL (normal ); Phosphorylated tau: 18.54 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild ventricular enlargement and mild hippocampal atrophy, but other brain regions (whole brain, entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges. The MMSE score of 28 is normal, and while Aβ is mildly elevated, tau markers (T-tau, P-tau) are normal. APOE4-negative status and preserved cognitive function suggest no significant dementia pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mild hippocampal atrophy and elevated Aβ, but strong cognitive performance and normal tau levels)",
  "timestamp": "2025-07-25T21:07:01.924158"
}