{
  "ptid_time": "005_S_0324_2007-10-17",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0324/2007-10-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 16,940 mm³, 39.6% below the reference mean. With a Z-score of -0.91 (18.2th percentile), this represents normal volume ; hippocampal volume measures 4,458 mm³, 37.3% below the reference mean. With a Z-score of -3.42 (0.0th percentile), this represents profound atrophy; whole brain volume measures 866,197 mm³, 11.1% below the reference mean. With a Z-score of -1.40 (8.1th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,625 mm³, 55.8% below the reference mean. With a Z-score of -3.42 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 12,999 mm³, 23.6% below the reference mean. With a Z-score of -2.15 (1.6th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,436 mm³, 24.7% below the reference mean. With a Z-score of -2.14 (1.6th percentile), this represents significant atrophy. ",
  "text_data": "Age is 76.8 years. Gender is Female. Education: 14 years. MMSE: 22.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, along with significant atrophy in the fusiform gyrus and middle temporal gyrus—key regions affected in Alzheimer's disease. The MMSE score of 22 indicates cognitive impairment, and the absence of APOE4 does not rule out AD, as neurodegeneration patterns strongly suggest pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T21:05:21.269315"
}