{
  "ptid_time": "094_S_4162_2013-09-27",
  "img_path": "/data/qiuhui/data/adni/images/094_S_4162/2013-09-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 51,155 mm³, 82.3% above the reference mean. With a Z-score of 1.88 (97.0th percentile), this represents moderate enlargement; hippocampal volume measures 5,831 mm³, 18.0% below the reference mean. With a Z-score of -1.65 (4.9th percentile), this represents moderate atrophy; whole brain volume measures 1,023,380 mm³, 5.0% above the reference mean. With a Z-score of 0.63 (73.5th percentile), this represents normal volume ; entorhinal cortex volume measures 2,973 mm³, 19.1% below the reference mean. With a Z-score of -1.17 (12.1th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,856 mm³, 5.0% above the reference mean. With a Z-score of 0.45 (67.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,640 mm³, 7.7% above the reference mean. With a Z-score of 0.67 (74.7th percentile), this represents normal volume . ",
  "text_data": "Age is 73.3 years. Gender is Female. Education: 16 years. MMSE: 22.0. MoCA: 21.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.49 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate hippocampal atrophy (Z-score -1.65, 4.9th percentile) and mild entorhinal cortex atrophy (Z-score -1.17, 12.1th percentile), both key regions affected in Alzheimer's disease. Combined with profound amyloid elevation (AV45), APOE4 homozygosity, and cognitive impairment (MMSE 22, MoCA 21), this strongly suggests Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T10:29:21.312261"
}