{
  "ptid_time": "053_S_2396_2012-02-07",
  "img_path": "/data/qiuhui/data/adni/images/053_S_2396/2012-02-07/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,188 mm³, 75.2% above the reference mean. With a Z-score of 1.72 (95.8th percentile), this represents moderate enlargement; hippocampal volume measures 8,623 mm³, 21.2% above the reference mean. With a Z-score of 1.94 (97.4th percentile), this represents moderate enlargement; whole brain volume measures 1,021,140 mm³, 4.8% above the reference mean. With a Z-score of 0.60 (72.6th percentile), this represents normal volume . ",
  "text_data": "Age is 70.7 years. Gender is Female. Education: 14 years. MMSE: 28.0. MoCA: 24.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is moderately enlarged (Z-score 1.72), which can indicate atrophy, but hippocampal volume is also moderately enlarged (Z-score 1.94), which is unusual in Alzheimer’s disease (AD). Cognitive scores (MMSE 28, MoCA 24) are borderline for MCI but not strongly suggestive of dementia. No APOE4 allele reduces AD risk.  \n\n**Diagnosis:** **MCI** (mild cognitive impairment)  \n**Confidence:** **Medium** (due to conflicting imaging findings—ventricular enlargement suggests neurodegeneration, but preserved hippocampal volume is atypical for AD; cognitive scores are ambiguous).",
  "timestamp": "2025-07-26T07:58:05.315236"
}