{
  "ptid_time": "127_S_4500_2012-02-08",
  "img_path": "/data/qiuhui/data/adni/images/127_S_4500/2012-02-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 51,859 mm³, 24.7% above the reference mean. With a Z-score of 3.88 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,616 mm³, 6.0% below the reference mean. With a Z-score of -3.31 (0.0th percentile), this represents profound atrophy; whole brain volume measures 917,992 mm³, 0.9% above the reference mean. With a Z-score of 0.10 (54.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,808 mm³, 25.9% below the reference mean. With a Z-score of -2.39 (0.8th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,945 mm³, 8.9% above the reference mean. With a Z-score of 1.12 (86.8th percentile), this represents mild enlargement; middle temporal gyrus volume measures 18,818 mm³, 4.2% above the reference mean. With a Z-score of 2.21 (98.7th percentile), this represents significant enlargement. ",
  "text_data": "Age is 90.3 years. Gender is Female. Education: 13 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Musculoskeletal; Endocrine-Metabolic; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 22.0. MoCA: 12.0. Logical Memory: 1.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.58 SUVR (profound elevated); Amyloid beta: 510.70 pg/mL (mild reduced); Total tau: 353.70 pg/mL (mild elevated); Phosphorylated tau: 37.41 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD). Elevated P-tau and AV45 (amyloid PET) further support AD pathology, while the MMSE (22) and MoCA (12) scores indicate significant cognitive impairment.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T13:18:34.752898"
}