{
  "ptid_time": "128_S_1043_2007-12-07",
  "img_path": "/data/qiuhui/data/adni/images/128_S_1043/2007-12-07/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 75,925 mm³, 152.9% above the reference mean. With a Z-score of 3.63 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,237 mm³, 22.3% below the reference mean. With a Z-score of -2.23 (1.3th percentile), this represents significant atrophy; whole brain volume measures 1,165,400 mm³, 2.7% above the reference mean. With a Z-score of 0.39 (65.0th percentile), this represents normal volume ; entorhinal cortex volume measures 3,820 mm³, 10.4% below the reference mean. With a Z-score of -0.72 (23.6th percentile), this represents normal volume ; fusiform gyrus volume measures 18,667 mm³, 6.2% below the reference mean. With a Z-score of -0.52 (30.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,136 mm³, 5.7% below the reference mean. With a Z-score of -0.47 (32.0th percentile), this represents normal volume . ",
  "text_data": "Age is 69.5 years. Gender is Male. Education: 16 years. MMSE: 25.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. Biomarker levels: Pittsburgh compound B: 1.57 SUVR (normal ); Amyloid beta: 685.00 pg/mL (normal ); Total tau: 180.10 pg/mL (normal ); Phosphorylated tau: 20.86 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.63) and significant hippocampal atrophy (Z-score -2.23), both strong indicators of neurodegeneration. However, CSF biomarkers (Aβ, T-tau, P-tau) are normal, and cognitive testing (MMSE 25) suggests only mild impairment, not full dementia.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural changes are severe, but biomarker and cognitive profiles do not yet meet dementia criteria.)",
  "timestamp": "2025-07-26T13:51:51.952616"
}