{
  "ptid_time": "057_S_0643_2006-06-21",
  "img_path": "/data/qiuhui/data/adni/images/057_S_0643/2006-06-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 18,668 mm³, 33.5% below the reference mean. With a Z-score of -0.77 (22.2th percentile), this represents normal volume ; hippocampal volume measures 8,008 mm³, 12.6% above the reference mean. With a Z-score of 1.15 (87.5th percentile), this represents mild enlargement; whole brain volume measures 1,098,540 mm³, 12.7% above the reference mean. With a Z-score of 1.60 (94.5th percentile), this represents moderate enlargement; entorhinal cortex volume measures 4,489 mm³, 22.2% above the reference mean. With a Z-score of 1.36 (91.4th percentile), this represents mild enlargement; fusiform gyrus volume measures 17,293 mm³, 1.6% above the reference mean. With a Z-score of 0.15 (56.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,045 mm³, 9.8% above the reference mean. With a Z-score of 0.85 (80.2th percentile), this represents normal volume . ",
  "text_data": "Age is 71.4 years. Gender is Female. Education: 15 years. Handedness: Right. Race: White. Medical history: Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Hematopoietic-Lymphatic; Renal-Genitourinary; Allergies or Drug Sensitivities; Malignancy; Major Surgical Procedures. MMSE: 29.0. Logical Memory: 10.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show normal or above-average volumes in all regions, including the hippocampus and entorhinal cortex, which are typically affected in Alzheimer's. The MMSE score of 29 is within the normal range, and while the presence of two APOE4 alleles increases genetic risk, there is no current evidence of cognitive impairment or structural brain atrophy.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T08:03:48.130692"
}