{
  "ptid_time": "014_S_1095_2006-12-03",
  "img_path": "/data/qiuhui/data/adni/images/014_S_1095/2006-12-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 69,602 mm³, 88.3% above the reference mean. With a Z-score of 2.38 (99.1th percentile), this represents significant enlargement; whole brain volume measures 936,897 mm³, 0.9% above the reference mean. With a Z-score of 0.11 (54.5th percentile), this represents normal volume . ",
  "text_data": "Age is 80.3 years. Gender is Female. Education: 12 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 1.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The significant ventricular enlargement (Z-score 2.38) suggests substantial atrophy, which is often seen in neurodegenerative conditions like Alzheimer's disease. The MMSE score of 25 is borderline, indicating possible cognitive impairment, but not severe enough for a definitive dementia diagnosis. The presence of one APOE4 allele increases Alzheimer's risk but is not diagnostic alone.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to borderline MMSE and lack of detailed neuropsychological testing)",
  "timestamp": "2025-07-25T23:47:28.803083"
}