{
  "ptid_time": "006_S_4546_2012-09-24",
  "img_path": "/data/qiuhui/data/adni/images/006_S_4546/2012-09-24/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 77,459 mm³, 101.1% above the reference mean. With a Z-score of 2.42 (99.2th percentile), this represents significant enlargement; hippocampal volume measures 5,278 mm³, 30.2% below the reference mean. With a Z-score of -2.94 (0.2th percentile), this represents significant atrophy; whole brain volume measures 1,094,020 mm³, 1.4% above the reference mean. With a Z-score of 0.18 (57.0th percentile), this represents normal volume ; entorhinal cortex volume measures 3,566 mm³, 13.0% below the reference mean. With a Z-score of -0.88 (18.8th percentile), this represents normal volume ; fusiform gyrus volume measures 20,418 mm³, 8.4% above the reference mean. With a Z-score of 0.71 (76.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,918 mm³, 20.7% below the reference mean. With a Z-score of -1.86 (3.1th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 71.5 years. Gender is Male. Education: 20 years. MMSE: 24.0. MoCA: 18.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal atrophy (Z-score -2.94) and moderate middle temporal gyrus atrophy (Z-score -1.86), both key regions affected in Alzheimer’s disease. The MMSE (24) and MoCA (18) scores indicate cognitive impairment, and the presence of one APOE4 allele increases Alzheimer’s risk. Ventricular enlargement further supports neurodegeneration.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T21:39:47.429830"
}