{
  "ptid_time": "068_S_2248_2013-02-11",
  "img_path": "/data/qiuhui/data/adni/images/068_S_2248/2013-02-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 55,041 mm³, 42.9% above the reference mean. With a Z-score of 1.03 (84.8th percentile), this represents mild enlargement; hippocampal volume measures 6,088 mm³, 19.5% below the reference mean. With a Z-score of -1.90 (2.9th percentile), this represents moderate atrophy; whole brain volume measures 844,050 mm³, 21.8% below the reference mean. With a Z-score of -2.83 (0.2th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,665 mm³, 35.0% below the reference mean. With a Z-score of -2.37 (0.9th percentile), this represents significant atrophy; fusiform gyrus volume measures 12,957 mm³, 31.2% below the reference mean. With a Z-score of -2.66 (0.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 18,818 mm³, 11.8% below the reference mean. With a Z-score of -1.06 (14.4th percentile), this represents mild atrophy. ",
  "text_data": "Age is 78.1 years. Gender is Male. Education: 12 years. MMSE: 27.0. MoCA: 21.0. Logical Memory: 5.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, and whole brain), alongside mild cognitive impairment (MoCA 21/30, MMSE 27/30). The APOE4 carrier status further increases Alzheimer's risk. The atrophy pattern and cognitive scores suggest neurodegeneration beyond normal aging.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T08:56:56.478409"
}