{
  "ptid_time": "035_S_2074_2012-11-27",
  "img_path": "/data/qiuhui/data/adni/images/035_S_2074/2012-11-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 25,166 mm³, 16.2% below the reference mean. With a Z-score of -0.38 (35.0th percentile), this represents normal volume ; hippocampal volume measures 7,504 mm³, 6.5% below the reference mean. With a Z-score of -0.65 (25.7th percentile), this represents normal volume ; whole brain volume measures 1,053,680 mm³, 7.1% below the reference mean. With a Z-score of -1.01 (15.7th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,111 mm³, 27.0% below the reference mean. With a Z-score of -1.87 (3.1th percentile), this represents moderate atrophy; fusiform gyrus volume measures 19,692 mm³, 1.1% below the reference mean. With a Z-score of -0.09 (46.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 23,429 mm³, 4.5% above the reference mean. With a Z-score of 0.37 (64.6th percentile), this represents normal volume . ",
  "text_data": "Age is 64.0 years. Gender is Male. Education: 16 years. MMSE: 29.0. MoCA: 28.0. Logical Memory: 7.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.05 SUVR (normal ); Amyloid beta: 1440.00 pg/mL (mild elevated); Total tau: 184.10 pg/mL (normal ); Phosphorylated tau: 15.85 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild whole brain atrophy and moderate entorhinal cortex atrophy, which are concerning for early neurodegenerative changes. However, cognitive scores (MMSE 29, MoCA 28) are intact, and CSF biomarkers (Aβ mildly elevated, normal tau) do not strongly support Alzheimer’s pathology.  \n**Diagnosis:** **MCI** (given structural changes without significant cognitive decline, but biomarker profile is atypical for AD).  \n**Confidence:** **Medium** (structural atrophy suggests neurodegeneration, but cognitive and biomarker findings are not fully consistent with typical AD progression).",
  "timestamp": "2025-07-26T05:53:30.119759"
}