{
  "ptid_time": "011_S_1282_2010-02-24",
  "img_path": "/data/qiuhui/data/adni/images/011_S_1282/2010-02-24/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 50,294 mm³, 36.1% above the reference mean. With a Z-score of 0.97 (83.5th percentile), this represents normal volume ; hippocampal volume measures 4,309 mm³, 33.7% below the reference mean. With a Z-score of -2.70 (0.3th percentile), this represents significant atrophy; whole brain volume measures 794,454 mm³, 14.4% below the reference mean. With a Z-score of -1.73 (4.2th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,446 mm³, 29.4% below the reference mean. With a Z-score of -1.59 (5.6th percentile), this represents moderate atrophy; fusiform gyrus volume measures 14,955 mm³, 7.2% below the reference mean. With a Z-score of -0.54 (29.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 11,390 mm³, 36.8% below the reference mean. With a Z-score of -3.28 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 80.0 years. Gender is Female. Education: 12 years. MMSE: 16.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits significant hippocampal atrophy (Z-score -2.70, 0.3rd percentile) and profound middle temporal gyrus atrophy (Z-score -3.28, 0.1st percentile), both strongly associated with Alzheimer's pathology. The MMSE score of 16 indicates severe cognitive impairment, consistent with dementia. The absence of APOE4 does not rule out Alzheimer's, as atrophy patterns and cognitive deficits are highly suggestive.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-25T22:51:39.099860"
}