{
  "ptid_time": "068_S_0401_2006-12-15",
  "img_path": "/data/qiuhui/data/adni/images/068_S_0401/2006-12-15/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 45,558 mm³, 51.7% above the reference mean. With a Z-score of 1.23 (89.0th percentile), this represents mild enlargement; hippocampal volume measures 7,437 mm³, 7.4% below the reference mean. With a Z-score of -0.73 (23.1th percentile), this represents normal volume ; whole brain volume measures 1,281,390 mm³, 12.9% above the reference mean. With a Z-score of 1.83 (96.7th percentile), this represents moderate enlargement; entorhinal cortex volume measures 4,314 mm³, 1.2% above the reference mean. With a Z-score of 0.08 (53.3th percentile), this represents normal volume ; fusiform gyrus volume measures 17,625 mm³, 11.5% below the reference mean. With a Z-score of -0.95 (17.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 26,879 mm³, 19.9% above the reference mean. With a Z-score of 1.64 (95.0th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 64.4 years. Gender is Male. Education: 17 years. MMSE: 28.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild ventricular enlargement (consistent with aging or early neurodegenerative changes) and a normal hippocampal volume, which is atypical for Alzheimer's disease. The MMSE score of 28 is within the normal range, and the APOE4 carrier status (heterozygous) slightly increases Alzheimer's risk but is not diagnostic. The fusiform gyrus is slightly reduced but still within normal limits, while other regions (whole brain, middle temporal gyrus) are enlarged, suggesting no widespread atrophy.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to the lack of significant atrophy in Alzheimer’s-vulnerable regions and normal MMSE, but ventricular enlargement warrants caution)",
  "timestamp": "2025-07-26T08:47:18.351993"
}