{
  "ptid_time": "099_S_4086_2012-07-09",
  "img_path": "/data/qiuhui/data/adni/images/099_S_4086/2012-07-09/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,907 mm³, 52.9% above the reference mean. With a Z-score of 1.54 (93.8th percentile), this represents moderate enlargement; hippocampal volume measures 5,809 mm³, 16.6% below the reference mean. With a Z-score of -1.44 (7.5th percentile), this represents mild atrophy; whole brain volume measures 773,983 mm³, 24.8% below the reference mean. With a Z-score of -3.25 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 82.8 years. Gender is Male. Education: 20 years. MMSE: 26.0. MoCA: 26.0. Logical Memory: 15.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound whole brain atrophy (Z-score -3.25) and mild hippocampal atrophy (Z-score -1.44), alongside moderate ventricular enlargement, which are consistent with neurodegenerative changes. Despite normal MMSE and MoCA scores (26/30), the structural changes suggest cognitive impairment, though the absence of APOE4 and preserved cognitive scores complicate the diagnosis.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting imaging and cognitive findings, but structural changes strongly suggest neurodegeneration)",
  "timestamp": "2025-07-26T11:05:33.527190"
}