{
  "ptid_time": "022_S_0096_2006-01-18",
  "img_path": "/data/qiuhui/data/adni/images/022_S_0096/2006-01-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 74,504 mm³, 93.4% above the reference mean. With a Z-score of 2.24 (98.7th percentile), this represents significant enlargement; hippocampal volume measures 7,465 mm³, 1.2% below the reference mean. With a Z-score of -0.12 (45.2th percentile), this represents normal volume ; whole brain volume measures 1,050,940 mm³, 2.6% below the reference mean. With a Z-score of -0.34 (36.6th percentile), this represents normal volume ; entorhinal cortex volume measures 3,213 mm³, 21.6% below the reference mean. With a Z-score of -1.47 (7.1th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,815 mm³, 5.4% below the reference mean. With a Z-score of -0.46 (32.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,680 mm³, 1.6% above the reference mean. With a Z-score of 0.14 (55.7th percentile), this represents normal volume . ",
  "text_data": "Age is 79.6 years. Gender is Male. Education: 20 years. MMSE: 30.0. Logical Memory: 18.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 915.30 pg/mL (normal ); Total tau: 124.90 pg/mL (mild reduced); Phosphorylated tau: 12.17 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (consistent with atrophy) and mild entorhinal cortex atrophy, but hippocampal and whole brain volumes are within normal limits. The MMSE score of 30 is intact, and biomarkers (Aβ normal, T-tau/P-tau mildly reduced) do not strongly suggest Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to conflicting atrophy patterns and normal cognition despite some structural changes)",
  "timestamp": "2025-07-26T02:00:10.562009"
}