{
  "ptid_time": "057_S_1217_2008-02-13",
  "img_path": "/data/qiuhui/data/adni/images/057_S_1217/2008-02-13/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 53,444 mm³, 139.3% above the reference mean. With a Z-score of 3.49 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,017 mm³, 21.7% below the reference mean. With a Z-score of -2.44 (0.7th percentile), this represents significant atrophy; whole brain volume measures 978,545 mm³, 4.9% below the reference mean. With a Z-score of -0.61 (27.0th percentile), this represents normal volume ; entorhinal cortex volume measures 3,198 mm³, 17.9% below the reference mean. With a Z-score of -1.38 (8.3th percentile), this represents mild atrophy; fusiform gyrus volume measures 14,823 mm³, 18.6% below the reference mean. With a Z-score of -2.09 (1.8th percentile), this represents significant atrophy; middle temporal gyrus volume measures 18,617 mm³, 9.3% below the reference mean. With a Z-score of -0.82 (20.5th percentile), this represents normal volume . ",
  "text_data": "Age is 68.8 years. Gender is Female. Education: 16 years. MMSE: 27.0. Logical Memory: 5.0. APOEε4 alleles: 2.0. Biomarker levels: Amyloid beta: 796.40 pg/mL (normal ); Total tau: 262.20 pg/mL (normal ); Phosphorylated tau: 23.67 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement and significant hippocampal atrophy, both strong indicators of neurodegeneration. Despite normal Aβ, T-tau, and P-tau levels, the structural changes (especially hippocampal and fusiform gyrus atrophy) alongside a slightly below-average MMSE score (27/30) suggest cognitive impairment.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Biomarkers are normal, but structural atrophy is concerning; clinical correlation needed for definitive diagnosis.)",
  "timestamp": "2025-07-26T08:09:18.825885"
}