{
  "ptid_time": "127_S_4148_2015-08-04",
  "img_path": "/data/qiuhui/data/adni/images/127_S_4148/2015-08-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 16,056 mm³, 58.3% below the reference mean. With a Z-score of -1.40 (8.1th percentile), this represents mild atrophy; hippocampal volume measures 8,384 mm³, 10.9% above the reference mean. With a Z-score of 1.06 (85.6th percentile), this represents mild enlargement; whole brain volume measures 1,091,050 mm³, 1.1% above the reference mean. With a Z-score of 0.14 (55.6th percentile), this represents normal volume ; entorhinal cortex volume measures 3,803 mm³, 7.3% below the reference mean. With a Z-score of -0.49 (31.1th percentile), this represents normal volume ; fusiform gyrus volume measures 20,383 mm³, 8.2% above the reference mean. With a Z-score of 0.70 (75.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,870 mm³, 2.2% below the reference mean. With a Z-score of -0.20 (42.2th percentile), this represents normal volume . ",
  "text_data": "Age is 77.0 years. Gender is Male. Education: 18 years. MMSE: 30.0. MoCA: 25.0. Logical Memory: 16.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.99 SUVR (normal ); Amyloid beta: 1301.00 pg/mL (normal ); Total tau: 188.80 pg/mL (normal ); Phosphorylated tau: 14.30 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild ventricular atrophy but otherwise normal or even slightly enlarged volumes in key regions (hippocampus, whole brain, fusiform gyrus). Cognitive scores are borderline (MMSE 30, MoCA 25), but CSF and amyloid PET biomarkers are normal, and there is no APOE4 risk allele.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mild ventricular atrophy and borderline MoCA, but biomarker profile strongly supports normal aging)",
  "timestamp": "2025-07-26T13:13:41.462631"
}