{
  "ptid_time": "128_S_0947_2007-04-17",
  "img_path": "/data/qiuhui/data/adni/images/128_S_0947/2007-04-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 50,136 mm³, 35.6% above the reference mean. With a Z-score of 0.96 (83.2th percentile), this represents normal volume ; hippocampal volume measures 4,374 mm³, 32.7% below the reference mean. With a Z-score of -2.62 (0.4th percentile), this represents significant atrophy; whole brain volume measures 806,564 mm³, 13.1% below the reference mean. With a Z-score of -1.57 (5.8th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,614 mm³, 24.5% below the reference mean. With a Z-score of -1.32 (9.3th percentile), this represents mild atrophy; fusiform gyrus volume measures 13,807 mm³, 14.3% below the reference mean. With a Z-score of -1.07 (14.1th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,502 mm³, 8.5% below the reference mean. With a Z-score of -0.75 (22.6th percentile), this represents normal volume . ",
  "text_data": "Age is 83.1 years. Gender is Female. Education: 13 years. MMSE: 25.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal atrophy (Z-score -2.62, 0.4th percentile) and moderate whole-brain atrophy (Z-score -1.57, 5.8th percentile), which are strong indicators of neurodegeneration. The MMSE score of 25 is borderline, but given the structural changes, this likely reflects cognitive impairment rather than normal aging.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely progressing toward dementia given the degree of atrophy)  \n**Confidence:** **High** (due to clear hippocampal and whole-brain atrophy, borderline MMSE, and APOE4 carrier status)",
  "timestamp": "2025-07-26T13:51:08.323493"
}