{
  "ptid_time": "137_S_0631_2007-01-17",
  "img_path": "/data/qiuhui/data/adni/images/137_S_0631/2007-01-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,488 mm³, 28.5% above the reference mean. With a Z-score of 0.68 (75.2th percentile), this represents normal volume ; hippocampal volume measures 4,547 mm³, 39.8% below the reference mean. With a Z-score of -3.89 (0.0th percentile), this represents profound atrophy; whole brain volume measures 876,091 mm³, 18.8% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,266 mm³, 44.7% below the reference mean. With a Z-score of -3.03 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 15,403 mm³, 18.2% below the reference mean. With a Z-score of -1.55 (6.0th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,955 mm³, 25.2% below the reference mean. With a Z-score of -2.27 (1.2th percentile), this represents significant atrophy. ",
  "text_data": "Age is 77.6 years. Gender is Male. Education: 14 years. MMSE: 22.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus and entorhinal cortex, along with significant whole brain and middle temporal gyrus atrophy—key regions affected in Alzheimer’s disease. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele further supports Alzheimer’s risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T16:12:26.867857"
}