{
  "ptid_time": "053_S_2396_2011-07-27",
  "img_path": "/data/qiuhui/data/adni/images/053_S_2396/2011-07-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,356 mm³, 75.8% above the reference mean. With a Z-score of 1.74 (95.9th percentile), this represents moderate enlargement; hippocampal volume measures 8,538 mm³, 20.0% above the reference mean. With a Z-score of 1.84 (96.7th percentile), this represents moderate enlargement; whole brain volume measures 1,026,130 mm³, 5.3% above the reference mean. With a Z-score of 0.66 (74.7th percentile), this represents normal volume . ",
  "text_data": "Age is 70.2 years. Gender is Female. Education: 14 years. Handedness: Right. Race: White. Medical history: Musculoskeletal; Smoking; Major Surgical Procedures. MMSE: 28.0. MoCA: 24.0. Logical Memory: 5.0. Laboratory findings: Phosphorus: 5.10 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.12 SUVR (normal ); Total tau: 218.70 pg/mL (normal ); Phosphorylated tau: 17.42 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is moderately enlarged (Z-score 1.74), which can indicate atrophy, but hippocampal volume is also enlarged (Z-score 1.84), which is atypical for Alzheimer’s. Whole brain volume is normal. Cognitive scores (MMSE 28, MoCA 24) are borderline for MCI but not dementia. Biomarkers (T-tau, P-tau, AV45) are normal, and APOE4-negative status reduces Alzheimer’s risk.  \n\n**Diagnosis:** **MCI** (mild cognitive impairment)  \n**Confidence:** **Medium** (due to conflicting imaging findings and borderline cognitive scores, but normal biomarkers suggest non-Alzheimer’s etiology)",
  "timestamp": "2025-07-26T07:57:57.883553"
}