{
  "ptid_time": "094_S_4503_2012-02-22",
  "img_path": "/data/qiuhui/data/adni/images/094_S_4503/2012-02-22/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 7,443 mm³, 4.6% above the reference mean. With a Z-score of 0.42 (66.4th percentile), this represents normal volume ; whole brain volume measures 1,070,660 mm³, 9.9% above the reference mean. With a Z-score of 1.24 (89.3th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,987 mm³, 8.6% above the reference mean. With a Z-score of 0.52 (70.0th percentile), this represents normal volume ; fusiform gyrus volume measures 22,739 mm³, 33.7% above the reference mean. With a Z-score of 3.06 (99.9th percentile), this represents profound enlargement; middle temporal gyrus volume measures 22,226 mm³, 15.9% above the reference mean. With a Z-score of 1.38 (91.7th percentile), this represents mild enlargement. ",
  "text_data": "Age is 71.7 years. Gender is Female. Education: 19 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Dermatologic-Connective Tissue; Gastrointestinal; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 30.0. MoCA: 27.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.04 SUVR (normal ); Amyloid beta: 1245.00 pg/mL (normal ); Total tau: 180.10 pg/mL (normal ); Phosphorylated tau: 17.10 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal, entorhinal cortex, and whole brain volumes are within normal or mildly enlarged ranges, with no significant atrophy. Biomarkers (Aβ, T-tau, P-tau, AV45) are normal, and cognitive scores (MMSE 30, MoCA 27) are intact, with no indication of impairment. The fusiform gyrus enlargement is atypical but not indicative of neurodegeneration.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T10:31:11.084173"
}