{
  "ptid_time": "099_S_2146_2017-10-06",
  "img_path": "/data/qiuhui/data/adni/images/099_S_2146/2017-10-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 35,362 mm³, 8.2% below the reference mean. With a Z-score of -0.20 (42.2th percentile), this represents normal volume ; hippocampal volume measures 8,550 mm³, 13.1% above the reference mean. With a Z-score of 1.28 (90.0th percentile), this represents mild enlargement; whole brain volume measures 1,111,190 mm³, 2.9% above the reference mean. With a Z-score of 0.38 (64.9th percentile), this represents normal volume ; entorhinal cortex volume measures 5,498 mm³, 34.1% above the reference mean. With a Z-score of 2.31 (99.0th percentile), this represents significant enlargement; fusiform gyrus volume measures 20,459 mm³, 8.6% above the reference mean. With a Z-score of 0.73 (76.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 26,061 mm³, 22.1% above the reference mean. With a Z-score of 1.99 (97.7th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 73.3 years. Gender is Male. Education: 18 years. MMSE: 30.0. MoCA: 24.0. Logical Memory: 17.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.98 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume data shows normal or above-average volumes in key regions (hippocampus, entorhinal cortex, middle temporal gyrus), with no atrophy typically seen in Alzheimer's. The MMSE is normal (30/30), but the MoCA (24/30) suggests mild cognitive concerns, though not severe enough for dementia. No APOE4 or amyloid pathology (AV45 normal) further reduces Alzheimer's likelihood.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment)**  \n**Confidence:** **Medium** (MoCA indicates subtle deficits, but structural and biomarker data do not strongly support neurodegeneration).",
  "timestamp": "2025-07-26T11:03:28.267083"
}