{
  "ptid_time": "003_S_5187_2013-06-07",
  "img_path": "/data/qiuhui/data/adni/images/003_S_5187/2013-06-07/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 4,977 mm³, 35.2% below the reference mean. With a Z-score of -3.95 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 61.4 years. Gender is Female. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Endocrine-Metabolic. MMSE: 24.0. MoCA: 13.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.40 SUVR (significant elevated); Amyloid beta: 725.10 pg/mL (normal ); Total tau: 379.00 pg/mL (moderate elevated); Phosphorylated tau: 36.15 pg/mL (moderate elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume is severely reduced (Z-score -3.95, 0.0th percentile), indicating profound atrophy. Despite normal Aβ levels, elevated T-tau, P-tau, and AV45 suggest neurodegeneration, and cognitive scores (MMSE 24, MoCA 13) are impaired but not yet severe.  \n**Diagnosis:** **MCI (likely prodromal Alzheimer’s due to biomarker profile)**  \n**Confidence:** **High**  \n\n*(Note: The Aβ-normal result is atypical for AD, but the tau/AV45 elevations and hippocampal atrophy strongly suggest neurodegenerative MCI. A non-AD tauopathy or mixed pathology is possible but less likely.)*",
  "timestamp": "2025-07-25T20:58:54.320883"
}