{
  "ptid_time": "098_S_0160_2011-03-06",
  "img_path": "/data/qiuhui/data/adni/images/098_S_0160/2011-03-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 75,503 mm³, 60.6% above the reference mean. With a Z-score of 1.76 (96.1th percentile), this represents moderate enlargement; hippocampal volume measures 3,922 mm³, 43.7% below the reference mean. With a Z-score of -3.78 (0.0th percentile), this represents profound atrophy; whole brain volume measures 920,194 mm³, 10.6% below the reference mean. With a Z-score of -1.39 (8.3th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,814 mm³, 54.3% below the reference mean. With a Z-score of -3.55 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 13,282 mm³, 26.5% below the reference mean. With a Z-score of -2.29 (1.1th percentile), this represents significant atrophy; middle temporal gyrus volume measures 18,039 mm³, 10.6% below the reference mean. With a Z-score of -0.95 (17.2th percentile), this represents normal volume . ",
  "text_data": "Age is 80.2 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Musculoskeletal; Renal-Genitourinary; Smoking; Malignancy; Major Surgical Procedures. MMSE: 21.0. MoCA: 17.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.40 SUVR (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD), along with significant atrophy in the fusiform gyrus. Ventricular enlargement and mild whole-brain atrophy further support neurodegeneration. Clinically, the patient has cognitive impairment (MMSE 21, MoCA 17) and an elevated amyloid PET (AV45), consistent with AD pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T10:37:08.225665"
}