{
  "ptid_time": "141_S_1004_2011-12-28",
  "img_path": "/data/qiuhui/data/adni/images/141_S_1004/2011-12-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,626 mm³, 155.2% above the reference mean. With a Z-score of 3.55 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,678 mm³, 34.2% below the reference mean. With a Z-score of -3.14 (0.1th percentile), this represents profound atrophy; whole brain volume measures 793,768 mm³, 18.6% below the reference mean. With a Z-score of -2.34 (1.0th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,213 mm³, 67.0% below the reference mean. With a Z-score of -4.11 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 12,905 mm³, 24.1% below the reference mean. With a Z-score of -2.20 (1.4th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,798 mm³, 28.0% below the reference mean. With a Z-score of -2.43 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 78.9 years. Gender is Female. Education: 12 years. MMSE: 15.0. MoCA: 13.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.63 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex) alongside significant whole-brain and temporal lobe atrophy, along with ventricular enlargement. The cognitive scores (MMSE 15, MoCA 13) indicate severe impairment, and the elevated AV45 (amyloid PET) supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T16:52:59.003485"
}