{
  "ptid_time": "082_S_4090_2011-06-20",
  "img_path": "/data/qiuhui/data/adni/images/082_S_4090/2011-06-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 26,793 mm³, 30.4% below the reference mean. With a Z-score of -0.73 (23.3th percentile), this represents normal volume ; whole brain volume measures 1,078,220 mm³, 0.1% below the reference mean. With a Z-score of -0.01 (49.4th percentile), this represents normal volume ; entorhinal cortex volume measures 4,288 mm³, 4.6% above the reference mean. With a Z-score of 0.31 (62.2th percentile), this represents normal volume ; fusiform gyrus volume measures 19,173 mm³, 1.8% above the reference mean. With a Z-score of 0.15 (56.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,265 mm³, 0.3% below the reference mean. With a Z-score of -0.03 (48.8th percentile), this represents normal volume . ",
  "text_data": "Age is 71.4 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Endocrine-Metabolic; Allergies or Drug Sensitivities; Smoking; Major Surgical Procedures. MMSE: 30.0. MoCA: 25.0. Logical Memory: 19.0. Laboratory findings: MCH: 35.00 (significant elevated); Total Bilirubin: 0.80 (significant elevated); Direct Bilirubin: 0.30 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.09 SUVR (normal ); Amyloid beta: 1687.00 pg/mL (moderate elevated); Total tau: 195.70 pg/mL (normal ); Phosphorylated tau: 17.53 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "Reasoning: The brain volumes (ventricular, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) are all within normal ranges based on Z-scores and percentiles. The MMSE score of 30 is normal, but the MoCA score of 25 suggests mild cognitive impairment (MCI). Biomarkers show moderately elevated Aβ (amyloid) but normal tau and AV45 (amyloid PET), which may indicate early amyloid accumulation without significant neurodegeneration.  \nDiagnosis: MCI  \nConfidence: Medium (due to conflicting MMSE/MoCA scores and moderately elevated Aβ without other biomarker abnormalities)",
  "timestamp": "2025-07-26T10:04:40.971618"
}