{
  "ptid_time": "099_S_0352_2006-10-25",
  "img_path": "/data/qiuhui/data/adni/images/099_S_0352/2006-10-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 35,713 mm³, 27.2% above the reference mean. With a Z-score of 0.62 (73.4th percentile), this represents normal volume ; hippocampal volume measures 5,351 mm³, 24.8% below the reference mean. With a Z-score of -2.27 (1.1th percentile), this represents significant atrophy; whole brain volume measures 783,903 mm³, 19.6% below the reference mean. With a Z-score of -2.46 (0.7th percentile), this represents significant atrophy; entorhinal cortex volume measures 3,493 mm³, 4.9% below the reference mean. With a Z-score of -0.30 (38.2th percentile), this represents normal volume ; fusiform gyrus volume measures 15,318 mm³, 10.0% below the reference mean. With a Z-score of -0.91 (18.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,024 mm³, 16.4% below the reference mean. With a Z-score of -1.42 (7.7th percentile), this represents mild atrophy. ",
  "text_data": "Age is 77.5 years. Gender is Female. Education: 14 years. MMSE: 30.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant atrophy in the hippocampus (-2.27 Z-score) and whole brain (-2.46 Z-score), which are strong indicators of neurodegeneration. However, the MMSE score of 30 is normal, suggesting preserved cognitive function despite structural changes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (due to significant atrophy in key regions but intact cognition on MMSE).  \n\n**Confidence:** **Medium** (high confidence in structural findings, but cognitive testing does not yet align with dementia; APOE4-negative status may suggest slower progression).",
  "timestamp": "2025-07-26T10:54:42.714088"
}