{
  "ptid_time": "127_S_0260_2006-11-02",
  "img_path": "/data/qiuhui/data/adni/images/127_S_0260/2006-11-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 24,171 mm³, 13.9% below the reference mean. With a Z-score of -0.32 (37.5th percentile), this represents normal volume ; hippocampal volume measures 6,158 mm³, 13.4% below the reference mean. With a Z-score of -1.23 (10.9th percentile), this represents mild atrophy; whole brain volume measures 879,901 mm³, 9.7% below the reference mean. With a Z-score of -1.22 (11.1th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,719 mm³, 28.5% above the reference mean. With a Z-score of 1.75 (96.0th percentile), this represents moderate enlargement; fusiform gyrus volume measures 15,224 mm³, 10.5% below the reference mean. With a Z-score of -0.96 (16.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,466 mm³, 8.9% below the reference mean. With a Z-score of -0.77 (22.0th percentile), this represents normal volume . ",
  "text_data": "Age is 79.1 years. Gender is Female. Education: 13 years. MMSE: 28.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal and whole brain volumes show mild atrophy (Z-scores of -1.23 and -1.22, respectively), which may suggest early neurodegenerative changes. However, the MMSE score of 28 is within the normal range, and there is no APOE4 risk allele, making significant cognitive impairment less likely. The entorhinal cortex enlargement is atypical and may warrant further investigation.  \n\n**Diagnosis:** Mild Cognitive Impairment (MCI)  \n**Confidence:** Medium (due to conflicting imaging findings and normal MMSE)",
  "timestamp": "2025-07-26T12:58:02.699857"
}