{
  "ptid_time": "141_S_0851_2006-09-26",
  "img_path": "/data/qiuhui/data/adni/images/141_S_0851/2006-09-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,439 mm³, 48.6% below the reference mean. With a Z-score of -1.11 (13.3th percentile), this represents mild atrophy; hippocampal volume measures 7,772 mm³, 9.2% above the reference mean. With a Z-score of 0.85 (80.2th percentile), this represents normal volume ; whole brain volume measures 1,017,030 mm³, 4.3% above the reference mean. With a Z-score of 0.55 (70.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,692 mm³, 26.7% below the reference mean. With a Z-score of -1.64 (5.1th percentile), this represents moderate atrophy; fusiform gyrus volume measures 17,457 mm³, 2.6% above the reference mean. With a Z-score of 0.24 (59.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,490 mm³, 14.0% below the reference mean. With a Z-score of -1.21 (11.2th percentile), this represents mild atrophy. ",
  "text_data": "Age is 72.5 years. Gender is Female. Education: 12 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Musculoskeletal; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 1.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 596.90 pg/mL (mild reduced); Total tau: 341.00 pg/mL (mild elevated); Phosphorylated tau: 36.58 pg/mL (moderate elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows mild ventricular atrophy and moderate entorhinal cortex atrophy, which are early indicators of neurodegeneration, alongside mild reductions in Aβ and elevated tau biomarkers (T-tau and P-tau). The MMSE score of 25 is borderline, suggesting possible cognitive impairment, but hippocampal and whole-brain volumes are normal, which may argue against advanced dementia.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Biomarkers and some atrophy suggest early neurodegeneration, but preserved hippocampal volume and near-normal MMSE leave some uncertainty.)",
  "timestamp": "2025-07-26T16:50:13.519100"
}