{
  "ptid_time": "022_S_0096_2010-02-26",
  "img_path": "/data/qiuhui/data/adni/images/022_S_0096/2010-02-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 84,342 mm³, 79.4% above the reference mean. With a Z-score of 2.31 (98.9th percentile), this represents significant enlargement; hippocampal volume measures 6,949 mm³, 0.3% below the reference mean. With a Z-score of -0.02 (49.1th percentile), this represents normal volume ; whole brain volume measures 1,046,030 mm³, 1.6% above the reference mean. With a Z-score of 0.21 (58.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,372 mm³, 15.0% below the reference mean. With a Z-score of -0.98 (16.2th percentile), this represents normal volume ; fusiform gyrus volume measures 18,086 mm³, 0.1% above the reference mean. With a Z-score of 0.01 (50.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,113 mm³, 4.7% above the reference mean. With a Z-score of 0.42 (66.2th percentile), this represents normal volume . ",
  "text_data": "Age is 83.6 years. Gender is Male. Education: 20 years. MMSE: 30.0. Logical Memory: 24.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1033.00 pg/mL (normal ); Total tau: 135.20 pg/mL (mild reduced); Phosphorylated tau: 12.55 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is significantly enlarged (Z-score 2.31), which is often associated with neurodegeneration, but hippocampal volume is normal (Z-score -0.02). Aβ is normal, and tau levels are mildly reduced, which does not strongly support Alzheimer’s pathology. The MMSE score of 30 is intact, and there are no significant cognitive complaints.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (ventricular enlargement is notable, but other biomarkers and cognitive performance suggest no impairment)",
  "timestamp": "2025-07-26T02:00:52.041350"
}