{
  "ptid_time": "035_S_4414_2015-04-08",
  "img_path": "/data/qiuhui/data/adni/images/035_S_4414/2015-04-08/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,319 mm³, 40.2% above the reference mean. With a Z-score of 1.01 (84.3th percentile), this represents mild enlargement; hippocampal volume measures 5,333 mm³, 30.6% below the reference mean. With a Z-score of -3.43 (0.0th percentile), this represents profound atrophy; whole brain volume measures 949,683 mm³, 7.7% below the reference mean. With a Z-score of -0.96 (16.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,473 mm³, 36.5% below the reference mean. With a Z-score of -2.83 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 12,489 mm³, 31.4% below the reference mean. With a Z-score of -3.54 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 15,923 mm³, 22.4% below the reference mean. With a Z-score of -1.99 (2.3th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 63.8 years. Gender is Female. Education: 18 years. MMSE: 21.0. MoCA: 14.0. Logical Memory: 1.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus, entorhinal cortex, and fusiform gyrus—key regions affected in Alzheimer's disease. The MMSE (21) and MoCA (14) scores indicate significant cognitive impairment, consistent with dementia rather than MCI. The presence of an APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T05:56:35.470242"
}