{
  "ptid_time": "013_S_1276_2007-03-28",
  "img_path": "/data/qiuhui/data/adni/images/013_S_1276/2007-03-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,359 mm³, 154.2% above the reference mean. With a Z-score of 3.53 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,173 mm³, 13.2% below the reference mean. With a Z-score of -1.21 (11.2th percentile), this represents mild atrophy; whole brain volume measures 871,252 mm³, 10.6% below the reference mean. With a Z-score of -1.34 (9.1th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,171 mm³, 13.6% above the reference mean. With a Z-score of 0.83 (79.7th percentile), this represents normal volume ; fusiform gyrus volume measures 16,819 mm³, 1.1% below the reference mean. With a Z-score of -0.10 (45.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 15,608 mm³, 18.6% below the reference mean. With a Z-score of -1.61 (5.3th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 71.8 years. Gender is Female. Education: 14 years. Handedness: Right. Race: White. Medical history: Respiratory; Smoking; Malignancy; Major Surgical Procedures. MMSE: 30.0. Logical Memory: 16.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 428.80 pg/mL (moderate reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.53) and mild hippocampal atrophy (Z-score -1.21), along with mild whole brain atrophy (Z-score -1.34) and moderate middle temporal gyrus atrophy (Z-score -1.61). Despite these structural changes, the MMSE score of 30 is normal, and Aβ is only moderately reduced, suggesting no significant cognitive impairment at this stage.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural changes are concerning, but cognitive performance remains intact, making early MCI more likely than dementia.)",
  "timestamp": "2025-07-25T23:28:17.388199"
}