{
  "ptid_time": "153_S_4372_2013-12-11",
  "img_path": "/data/qiuhui/data/adni/images/153_S_4372/2013-12-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,730 mm³, 22.6% below the reference mean. With a Z-score of -0.52 (30.3th percentile), this represents normal volume ; hippocampal volume measures 7,830 mm³, 10.1% above the reference mean. With a Z-score of 0.92 (82.2th percentile), this represents normal volume ; whole brain volume measures 944,967 mm³, 3.0% below the reference mean. With a Z-score of -0.38 (35.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,858 mm³, 5.0% above the reference mean. With a Z-score of 0.31 (62.1th percentile), this represents normal volume ; fusiform gyrus volume measures 17,612 mm³, 3.5% above the reference mean. With a Z-score of 0.32 (62.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,450 mm³, 3.8% below the reference mean. With a Z-score of -0.33 (37.2th percentile), this represents normal volume . ",
  "text_data": "Age is 72.0 years. Gender is Female. Education: 18 years. MMSE: 30.0. MoCA: 24.0. Logical Memory: 18.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.07 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** All brain volume measures (ventricular, hippocampal, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) fall within normal ranges based on Z-scores and percentiles. The MMSE score of 30 is optimal, but the MoCA score of 24 suggests possible mild cognitive impairment (MCI), though not severe enough for dementia. The absence of APOE4 and normal AV45 (amyloid PET) further reduce the likelihood of Alzheimer’s pathology.  \n\n**Diagnosis:** **MCI** (Mild Cognitive Impairment)  \n**Confidence:** **Medium** (due to the borderline MoCA score but otherwise normal biomarkers and imaging)",
  "timestamp": "2025-07-26T17:14:45.483386"
}