{
  "ptid_time": "098_S_0160_2006-09-02",
  "img_path": "/data/qiuhui/data/adni/images/098_S_0160/2006-09-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 64,531 mm³, 67.5% above the reference mean. With a Z-score of 1.62 (94.7th percentile), this represents moderate enlargement; hippocampal volume measures 4,587 mm³, 39.3% below the reference mean. With a Z-score of -3.84 (0.0th percentile), this represents profound atrophy; whole brain volume measures 987,100 mm³, 8.6% below the reference mean. With a Z-score of -1.11 (13.3th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,238 mm³, 45.4% below the reference mean. With a Z-score of -3.08 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 16,837 mm³, 10.6% below the reference mean. With a Z-score of -0.90 (18.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,158 mm³, 10.2% below the reference mean. With a Z-score of -0.92 (17.9th percentile), this represents normal volume . ",
  "text_data": "Age is 75.7 years. Gender is Male. Education: 16 years. MMSE: 24.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). Moderate ventricular enlargement and mild whole-brain atrophy further support neurodegenerative changes. The MMSE score of 24 is borderline, consistent with mild cognitive impairment (MCI) or early dementia. The presence of one APOE4 allele increases AD risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**  \n\n*(The severe hippocampal/entorhinal atrophy, ventricular enlargement, and borderline MMSE strongly suggest dementia due to AD, with high confidence given the structural and genetic markers.)*",
  "timestamp": "2025-07-26T10:36:26.787699"
}