{
  "ptid_time": "022_S_1394_2008-05-27",
  "img_path": "/data/qiuhui/data/adni/images/022_S_1394/2008-05-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 72,225 mm³, 87.5% above the reference mean. With a Z-score of 2.10 (98.2th percentile), this represents significant enlargement; hippocampal volume measures 7,089 mm³, 6.2% below the reference mean. With a Z-score of -0.61 (27.2th percentile), this represents normal volume ; whole brain volume measures 1,036,370 mm³, 4.0% below the reference mean. With a Z-score of -0.52 (30.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,853 mm³, 30.4% below the reference mean. With a Z-score of -2.06 (2.0th percentile), this represents significant atrophy; fusiform gyrus volume measures 13,356 mm³, 29.1% below the reference mean. With a Z-score of -2.48 (0.7th percentile), this represents significant atrophy; middle temporal gyrus volume measures 18,098 mm³, 15.2% below the reference mean. With a Z-score of -1.37 (8.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 78.1 years. Gender is Male. Education: 18 years. MMSE: 20.0. Logical Memory: 6.0. Laboratory findings: . APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 371.00 pg/mL (moderate reduced); Total tau: 237.60 pg/mL (normal ); Phosphorylated tau: 23.81 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (indicative of brain atrophy) and marked atrophy in the entorhinal cortex and fusiform gyrus—key regions affected in Alzheimer's disease. The MMSE score of 20, along with moderate Aβ reduction (suggestive of amyloid pathology), supports cognitive impairment consistent with dementia.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T02:11:25.856591"
}