{
  "ptid_time": "133_S_0638_2008-09-29",
  "img_path": "/data/qiuhui/data/adni/images/133_S_0638/2008-09-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 60,946 mm³, 29.6% above the reference mean. With a Z-score of 0.86 (80.5th percentile), this represents normal volume ; hippocampal volume measures 3,993 mm³, 42.7% below the reference mean. With a Z-score of -3.69 (0.0th percentile), this represents profound atrophy; whole brain volume measures 843,648 mm³, 18.0% below the reference mean. With a Z-score of -2.36 (0.9th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,907 mm³, 52.0% below the reference mean. With a Z-score of -3.40 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 10,426 mm³, 42.3% below the reference mean. With a Z-score of -3.66 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 13,067 mm³, 35.2% below the reference mean. With a Z-score of -3.16 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 85.1 years. Gender is Male. Education: 17 years. MMSE: 21.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) and significant whole-brain atrophy, alongside cognitive impairment (MMSE 21). The presence of two APOE4 alleles further supports Alzheimer's pathology.  \n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T15:23:50.820684"
}