{
  "ptid_time": "013_S_4985_2013-10-29",
  "img_path": "/data/qiuhui/data/adni/images/013_S_4985/2013-10-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 95,844 mm³, 241.5% above the reference mean. With a Z-score of 5.53 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,241 mm³, 26.3% below the reference mean. With a Z-score of -2.42 (0.8th percentile), this represents significant atrophy; whole brain volume measures 900,267 mm³, 7.6% below the reference mean. With a Z-score of -0.96 (16.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,814 mm³, 23.4% below the reference mean. With a Z-score of -1.44 (7.6th percentile), this represents mild atrophy; fusiform gyrus volume measures 16,791 mm³, 1.3% below the reference mean. With a Z-score of -0.12 (45.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,125 mm³, 15.9% below the reference mean. With a Z-score of -1.38 (8.4th percentile), this represents mild atrophy. ",
  "text_data": "Age is 79.7 years. Gender is Female. Education: 13 years. MMSE: 25.0. Logical Memory: 2.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement and significant hippocampal atrophy, both strong indicators of neurodegenerative disease. The MMSE score of 25 is borderline but, combined with structural changes, suggests cognitive impairment. The presence of one APOE4 allele further supports Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High** (due to severe hippocampal atrophy, ventricular enlargement, and mild cognitive decline)",
  "timestamp": "2025-07-25T23:36:21.306343"
}