{
  "ptid_time": "036_S_4714_2012-05-11",
  "img_path": "/data/qiuhui/data/adni/images/036_S_4714/2012-05-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 10,057 mm³, 55.0% below the reference mean. With a Z-score of -1.38 (8.4th percentile), this represents mild atrophy; hippocampal volume measures 7,656 mm³, 0.4% below the reference mean. With a Z-score of -0.04 (48.3th percentile), this represents normal volume ; whole brain volume measures 1,037,590 mm³, 0.8% above the reference mean. With a Z-score of 0.10 (54.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,745 mm³, 3.8% below the reference mean. With a Z-score of -0.29 (38.4th percentile), this represents normal volume ; fusiform gyrus volume measures 17,535 mm³, 3.7% below the reference mean. With a Z-score of -0.42 (33.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,923 mm³, 2.9% below the reference mean. With a Z-score of -0.26 (39.8th percentile), this represents normal volume . ",
  "text_data": "Age is 64.5 years. Gender is Female. Education: 18 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Renal-Genitourinary; Allergies or Drug Sensitivities. MMSE: 28.0. MoCA: 20.0. Logical Memory: 3.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.33 SUVR (moderate elevated); Amyloid beta: 915.70 pg/mL (normal ); Total tau: 378.10 pg/mL (moderate elevated); Phosphorylated tau: 36.67 pg/mL (moderate elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows mild ventricular atrophy but otherwise normal brain volumes, including the hippocampus. The MoCA score of 20 suggests cognitive impairment, while the MMSE of 28 is borderline normal. Biomarkers (elevated T-tau, P-tau, and AV45 with normal Aβ) suggest possible Alzheimer’s pathology, but the structural imaging does not yet show significant atrophy.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarker and imaging findings, with cognitive scores leaning toward impairment)",
  "timestamp": "2025-07-26T06:16:16.331633"
}