{
  "ptid_time": "023_S_0604_2006-12-12",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0604/2006-12-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 78,908 mm³, 67.8% above the reference mean. With a Z-score of 1.97 (97.6th percentile), this represents moderate enlargement; hippocampal volume measures 6,534 mm³, 6.2% below the reference mean. With a Z-score of -0.54 (29.5th percentile), this represents normal volume ; whole brain volume measures 1,095,720 mm³, 6.5% above the reference mean. With a Z-score of 0.85 (80.2th percentile), this represents normal volume ; entorhinal cortex volume measures 4,460 mm³, 12.4% above the reference mean. With a Z-score of 0.81 (79.1th percentile), this represents normal volume ; fusiform gyrus volume measures 18,171 mm³, 0.6% above the reference mean. With a Z-score of 0.05 (52.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,481 mm³, 3.4% below the reference mean. With a Z-score of -0.31 (37.9th percentile), this represents normal volume . ",
  "text_data": "Age is 87.0 years. Gender is Male. Education: 14 years. MMSE: 23.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient shows moderate ventricular enlargement (67.8% above mean, Z-score 1.97), which is often associated with brain atrophy, but hippocampal volume is only slightly reduced (-6.2%, Z-score -0.54) and within normal range. The MMSE score of 23 suggests mild cognitive impairment, but the absence of APOE4 and relatively preserved cortical volumes (entorhinal, fusiform, middle temporal gyrus) argue against advanced neurodegeneration.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to borderline MMSE and ventricular enlargement, but lack of significant hippocampal atrophy or APOE4 risk).",
  "timestamp": "2025-07-26T02:44:20.368715"
}