{
  "ptid_time": "128_S_1407_2013-02-05",
  "img_path": "/data/qiuhui/data/adni/images/128_S_1407/2013-02-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,568 mm³, 48.1% above the reference mean. With a Z-score of 1.10 (86.5th percentile), this represents mild enlargement; hippocampal volume measures 5,530 mm³, 22.3% below the reference mean. With a Z-score of -2.04 (2.1th percentile), this represents significant atrophy; whole brain volume measures 918,731 mm³, 5.7% below the reference mean. With a Z-score of -0.72 (23.5th percentile), this represents normal volume ; entorhinal cortex volume measures 1,274 mm³, 65.3% below the reference mean. With a Z-score of -4.01 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 12,965 mm³, 23.8% below the reference mean. With a Z-score of -2.17 (1.5th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,759 mm³, 23.0% below the reference mean. With a Z-score of -2.00 (2.3th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 79.6 years. Gender is Female. Education: 16 years. MMSE: 23.0. MoCA: 17.0. Logical Memory: 4.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), with profound entorhinal cortex atrophy (Z-score -4.01). The MMSE (23) and MoCA (17) scores indicate cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T13:55:16.179523"
}