{
  "ptid_time": "018_S_4868_2013-02-11",
  "img_path": "/data/qiuhui/data/adni/images/018_S_4868/2013-02-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 28,624 mm³, 25.7% below the reference mean. With a Z-score of -0.62 (26.9th percentile), this represents normal volume ; hippocampal volume measures 6,015 mm³, 20.4% below the reference mean. With a Z-score of -1.99 (2.3th percentile), this represents moderate atrophy; whole brain volume measures 1,018,260 mm³, 5.7% below the reference mean. With a Z-score of -0.74 (23.1th percentile), this represents normal volume ; entorhinal cortex volume measures 3,328 mm³, 18.8% below the reference mean. With a Z-score of -1.28 (10.1th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,628 mm³, 6.4% below the reference mean. With a Z-score of -0.55 (29.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,382 mm³, 4.5% below the reference mean. With a Z-score of -0.40 (34.3th percentile), this represents normal volume . ",
  "text_data": "Age is 77.6 years. Gender is Male. Education: 12 years. MMSE: 25.0. MoCA: 20.0. Laboratory findings: Vitamin B12: 1000.00 (significant elevated); Neutrophils: 40.00 (significant reduced); Lymphocytes: 49.10 (significant elevated); LDH: 126.00 (significant reduced); Cholesterol (High Performance): 114.00 (significant reduced). APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows moderate atrophy (Z-score -1.99, 2.3rd percentile), and the entorhinal cortex shows mild atrophy (Z-score -1.28, 10.1st percentile), both of which are key regions affected in Alzheimer’s disease. The cognitive scores (MMSE 25, MoCA 20) suggest mild cognitive impairment, and the presence of two APOE4 alleles increases Alzheimer’s risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer’s pathology)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T01:00:48.619647"
}