{
  "ptid_time": "037_S_0327_2008-05-23",
  "img_path": "/data/qiuhui/data/adni/images/037_S_0327/2008-05-23/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 56,450 mm³, 46.6% above the reference mean. With a Z-score of 1.12 (86.8th percentile), this represents mild enlargement; hippocampal volume measures 8,003 mm³, 5.9% above the reference mean. With a Z-score of 0.57 (71.7th percentile), this represents normal volume ; whole brain volume measures 1,070,700 mm³, 0.8% below the reference mean. With a Z-score of -0.10 (45.8th percentile), this represents normal volume ; entorhinal cortex volume measures 4,005 mm³, 2.3% below the reference mean. With a Z-score of -0.16 (43.7th percentile), this represents normal volume ; fusiform gyrus volume measures 19,382 mm³, 2.9% above the reference mean. With a Z-score of 0.25 (59.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,294 mm³, 0.2% below the reference mean. With a Z-score of -0.02 (49.2th percentile), this represents normal volume . ",
  "text_data": "Age is 72.0 years. Gender is Male. Education: 16 years. MMSE: 29.0. Logical Memory: 15.0. Laboratory findings: ALT (SGPT): 35.00 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Pittsburgh compound B: 1.58 SUVR (normal ); Amyloid beta: 1381.00 pg/mL (normal ); Total tau: 220.30 pg/mL (normal ); Phosphorylated tau: 18.92 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild ventricular enlargement but otherwise normal volumes in key regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus). Biomarkers (Aβ, T-tau, P-tau) are normal, and cognitive performance (MMSE 29/30) is intact. No significant atrophy or biomarker abnormalities suggest Alzheimer's pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T06:26:42.000711"
}