{
  "ptid_time": "128_S_4742_2012-05-31",
  "img_path": "/data/qiuhui/data/adni/images/128_S_4742/2012-05-31/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,676 mm³, 73.4% above the reference mean. With a Z-score of 1.68 (95.4th percentile), this represents moderate enlargement; hippocampal volume measures 7,506 mm³, 5.5% above the reference mean. With a Z-score of 0.50 (69.3th percentile), this represents normal volume ; whole brain volume measures 1,096,380 mm³, 12.5% above the reference mean. With a Z-score of 1.57 (94.2th percentile), this represents moderate enlargement; entorhinal cortex volume measures 3,857 mm³, 5.0% above the reference mean. With a Z-score of 0.31 (62.1th percentile), this represents normal volume ; fusiform gyrus volume measures 17,329 mm³, 1.9% above the reference mean. With a Z-score of 0.17 (56.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,693 mm³, 13.2% above the reference mean. With a Z-score of 1.14 (87.3th percentile), this represents mild enlargement. ",
  "text_data": "Age is 70.6 years. Gender is Female. Education: 14 years. Handedness: Right. Race: White. Medical history: Psychiatric; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 30.0. MoCA: 27.0. Logical Memory: 9.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.07 SUVR (normal ); Amyloid beta: 852.70 pg/mL (normal ); Total tau: 97.89 pg/mL (moderate reduced); Phosphorylated tau: 8.94 pg/mL (moderate reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume shows moderate enlargement (Z-score 1.68), which can indicate atrophy, but hippocampal, entorhinal cortex, fusiform gyrus, and middle temporal gyrus volumes are within normal ranges. Cognitive scores (MMSE 30, MoCA 27) are intact, and biomarkers (Aβ normal, reduced T-tau/P-tau) do not suggest Alzheimer’s pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (ventricular enlargement raises some concern, but other measures and biomarkers support normal cognition)",
  "timestamp": "2025-07-26T14:04:46.477030"
}