{
  "ptid_time": "141_S_2333_2018-12-26",
  "img_path": "/data/qiuhui/data/adni/images/141_S_2333/2018-12-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 41,737 mm³, 8.4% above the reference mean. With a Z-score of 0.20 (57.9th percentile), this represents normal volume ; hippocampal volume measures 5,954 mm³, 21.2% below the reference mean. With a Z-score of -2.07 (1.9th percentile), this represents significant atrophy; whole brain volume measures 1,037,360 mm³, 3.9% below the reference mean. With a Z-score of -0.51 (30.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,332 mm³, 18.7% below the reference mean. With a Z-score of -1.27 (10.2th percentile), this represents mild atrophy; fusiform gyrus volume measures 18,609 mm³, 1.2% below the reference mean. With a Z-score of -0.10 (45.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,201 mm³, 19.4% below the reference mean. With a Z-score of -1.74 (4.1th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 74.5 years. Gender is Male. Education: 12 years. MMSE: 24.0. MoCA: 24.0. Logical Memory: 6.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows significant atrophy (Z-score -2.07, 1.9th percentile), and the middle temporal gyrus also exhibits moderate atrophy (Z-score -1.74, 4.1th percentile), both of which are strongly associated with Alzheimer's pathology. The MMSE and MoCA scores (24/30) are borderline, suggesting mild cognitive impairment rather than severe dementia. The presence of one APOE4 allele further increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T17:01:12.496075"
}