{
  "ptid_time": "137_S_0994_2008-06-03",
  "img_path": "/data/qiuhui/data/adni/images/137_S_0994/2008-06-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 26,509 mm³, 42.3% above the reference mean. With a Z-score of 1.21 (88.7th percentile), this represents mild enlargement; hippocampal volume measures 6,792 mm³, 13.0% below the reference mean. With a Z-score of -1.81 (3.5th percentile), this represents moderate atrophy; whole brain volume measures 923,356 mm³, 11.3% below the reference mean. With a Z-score of -1.35 (8.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,095 mm³, 16.2% below the reference mean. With a Z-score of -1.27 (10.2th percentile), this represents mild atrophy; fusiform gyrus volume measures 12,226 mm³, 33.7% below the reference mean. With a Z-score of -3.06 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 17,923 mm³, 12.7% below the reference mean. With a Z-score of -1.05 (14.7th percentile), this represents mild atrophy. ",
  "text_data": "Age is 56.6 years. Gender is Female. Education: 18 years. MMSE: 26.0. Laboratory findings: MCH: 26.00 (significant reduced). APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions, including the hippocampus (moderate atrophy, 3.5th percentile) and fusiform gyrus (profound atrophy, 0.1st percentile), alongside mild-to-moderate whole-brain and temporal lobe atrophy. The MMSE score of 26 is borderline for mild cognitive impairment (MCI), and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely prodromal Alzheimer's given the biomarker profile).  \n\n**Confidence:** **High** (due to concordance between structural atrophy patterns, borderline cognitive scores, and genetic risk).",
  "timestamp": "2025-07-26T16:22:47.079451"
}