{
  "ptid_time": "098_S_0269_2008-04-05",
  "img_path": "/data/qiuhui/data/adni/images/098_S_0269/2008-04-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 55,538 mm³, 85.0% above the reference mean. With a Z-score of 2.02 (97.8th percentile), this represents significant enlargement; hippocampal volume measures 5,321 mm³, 33.7% below the reference mean. With a Z-score of -3.37 (0.0th percentile), this represents profound atrophy; whole brain volume measures 964,812 mm³, 15.0% below the reference mean. With a Z-score of -2.12 (1.7th percentile), this represents significant atrophy; entorhinal cortex volume measures 3,669 mm³, 13.9% below the reference mean. With a Z-score of -0.96 (16.7th percentile), this represents normal volume ; fusiform gyrus volume measures 11,569 mm³, 41.9% below the reference mean. With a Z-score of -3.48 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 16,444 mm³, 26.6% below the reference mean. With a Z-score of -2.19 (1.4th percentile), this represents significant atrophy. ",
  "text_data": "Age is 69.1 years. Gender is Male. Education: 16 years. MMSE: 22.0. Logical Memory: 0.0. Laboratory findings: Total Bilirubin: 0.80 (significant elevated). APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal and fusiform gyrus atrophy, significant whole brain and middle temporal gyrus atrophy, and marked ventricular enlargement, all consistent with Alzheimer's pathology. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T10:40:12.766423"
}