{
  "ptid_time": "098_S_4506_2013-08-02",
  "img_path": "/data/qiuhui/data/adni/images/098_S_4506/2013-08-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 74,228 mm³, 92.7% above the reference mean. With a Z-score of 2.22 (98.7th percentile), this represents significant enlargement; hippocampal volume measures 8,053 mm³, 6.5% above the reference mean. With a Z-score of 0.64 (73.8th percentile), this represents normal volume ; whole brain volume measures 1,028,830 mm³, 4.7% below the reference mean. With a Z-score of -0.61 (27.2th percentile), this represents normal volume ; entorhinal cortex volume measures 3,584 mm³, 12.6% below the reference mean. With a Z-score of -0.85 (19.6th percentile), this represents normal volume ; fusiform gyrus volume measures 16,370 mm³, 13.1% below the reference mean. With a Z-score of -1.12 (13.2th percentile), this represents mild atrophy; middle temporal gyrus volume measures 22,514 mm³, 5.5% above the reference mean. With a Z-score of 0.50 (69.0th percentile), this represents normal volume . ",
  "text_data": "Age is 72.5 years. Gender is Male. Education: 19 years. MMSE: 29.0. MoCA: 27.0. Logical Memory: 22.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The data shows significant ventricular enlargement (92.7% above mean, Z-score 2.22), which is a strong marker of neurodegeneration, along with mild atrophy in the fusiform gyrus (Z-score -1.12). However, hippocampal and whole brain volumes are within normal ranges, and cognitive scores (MMSE 29, MoCA 27) are intact. APOE4 negative status reduces Alzheimer's risk.  \n\nDiagnosis: **Mild Cognitive Impairment (MCI)**  \nConfidence: **Medium**  \n\n(While structural changes suggest early neurodegeneration, preserved cognition and normal hippocampal volume make dementia less likely. MCI is probable, but confidence is medium due to the absence of clear cognitive deficits.)",
  "timestamp": "2025-07-26T10:49:35.995309"
}