{
  "ptid_time": "023_S_0376_2006-04-03",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0376/2006-04-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 61,934 mm³, 60.8% above the reference mean. With a Z-score of 1.46 (92.7th percentile), this represents mild enlargement; hippocampal volume measures 7,036 mm³, 6.9% below the reference mean. With a Z-score of -0.68 (25.0th percentile), this represents normal volume ; whole brain volume measures 993,712 mm³, 7.9% below the reference mean. With a Z-score of -1.03 (15.1th percentile), this represents mild atrophy; entorhinal cortex volume measures 4,061 mm³, 1.0% below the reference mean. With a Z-score of -0.07 (47.4th percentile), this represents normal volume ; fusiform gyrus volume measures 17,368 mm³, 7.8% below the reference mean. With a Z-score of -0.66 (25.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,173 mm³, 10.2% below the reference mean. With a Z-score of -0.91 (18.1th percentile), this represents normal volume . ",
  "text_data": "Age is 70.5 years. Gender is Male. Education: 15 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Hepatic; Dermatologic-Connective Tissue; Musculoskeletal; Renal-Genitourinary; Major Surgical Procedures. MMSE: 28.0. Logical Memory: 3.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1148.00 pg/mL (normal ); Total tau: 160.00 pg/mL (mild reduced); Phosphorylated tau: 13.21 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The patient shows mild ventricular enlargement and mild whole brain atrophy, but hippocampal, entorhinal cortex, fusiform gyrus, and middle temporal gyrus volumes are within normal ranges. Cognitive testing (MMSE 28/30) is normal, and biomarkers (Aβ normal, tau reduced) do not suggest Alzheimer's pathology.  \nDiagnosis: CN (Cognitively Normal)  \nConfidence: Medium (due to mild structural changes but no clear cognitive or biomarker evidence of impairment)",
  "timestamp": "2025-07-26T02:41:29.328526"
}