{
  "ptid_time": "072_S_4102_2012-07-11",
  "img_path": "/data/qiuhui/data/adni/images/072_S_4102/2012-07-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 73,038 mm³, 227.0% above the reference mean. With a Z-score of 5.68 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,725 mm³, 38.5% below the reference mean. With a Z-score of -4.32 (0.0th percentile), this represents profound atrophy; whole brain volume measures 971,598 mm³, 5.6% below the reference mean. With a Z-score of -0.70 (24.3th percentile), this represents normal volume . ",
  "text_data": "Age is 67.9 years. Gender is Female. Education: 14 years. MMSE: 19.0. MoCA: 21.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 5.68) and severe hippocampal atrophy (Z-score -4.32), both strongly indicative of neurodegeneration. The cognitive scores (MMSE 19, MoCA 21) are below normal ranges, consistent with significant cognitive impairment.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given hippocampal atrophy, though APOE4-negative status slightly reduces certainty).  \n\n**Confidence:** **High** (due to severe structural changes and cognitive deficits, but medium if considering non-AD etiologies given APOE4-negative status).",
  "timestamp": "2025-07-26T09:17:12.771299"
}