{
  "ptid_time": "011_S_0856_2008-09-30",
  "img_path": "/data/qiuhui/data/adni/images/011_S_0856/2008-09-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 66,452 mm³, 121.3% above the reference mean. With a Z-score of 2.88 (99.8th percentile), this represents significant enlargement; hippocampal volume measures 6,054 mm³, 24.6% below the reference mean. With a Z-score of -2.46 (0.7th percentile), this represents significant atrophy; whole brain volume measures 1,097,330 mm³, 3.3% below the reference mean. With a Z-score of -0.46 (32.1th percentile), this represents normal volume ; entorhinal cortex volume measures 2,260 mm³, 47.0% below the reference mean. With a Z-score of -3.25 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 15,447 mm³, 22.4% below the reference mean. With a Z-score of -1.86 (3.1th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 14,997 mm³, 33.1% below the reference mean. With a Z-score of -2.73 (0.3th percentile), this represents significant atrophy. ",
  "text_data": "Age is 62.3 years. Gender is Male. Education: 13 years. MMSE: 22.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal and entorhinal cortex atrophy, both key regions affected in Alzheimer's disease (AD), along with ventricular enlargement indicative of brain volume loss. The MMSE score of 22 suggests cognitive impairment, and the presence of one APOE4 allele increases AD risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T22:49:15.362788"
}