{
  "ptid_time": "062_S_0793_2007-09-11",
  "img_path": "/data/qiuhui/data/adni/images/062_S_0793/2007-09-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 26,782 mm³, 10.8% below the reference mean. With a Z-score of -0.26 (39.9th percentile), this represents normal volume ; hippocampal volume measures 6,196 mm³, 22.8% below the reference mean. With a Z-score of -2.28 (1.1th percentile), this represents significant atrophy; whole brain volume measures 989,425 mm³, 12.8% below the reference mean. With a Z-score of -1.81 (3.5th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,489 mm³, 41.6% below the reference mean. With a Z-score of -2.88 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,428 mm³, 27.5% below the reference mean. With a Z-score of -2.29 (1.1th percentile), this represents significant atrophy; middle temporal gyrus volume measures 15,177 mm³, 32.3% below the reference mean. With a Z-score of -2.66 (0.4th percentile), this represents significant atrophy. ",
  "text_data": "Age is 69.9 years. Gender is Male. Education: 20 years. MMSE: 20.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) with Z-scores below -2, indicating severe volume loss. The MMSE score of 20 suggests cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High** (due to concordance between structural atrophy, low MMSE, and APOE4 status).",
  "timestamp": "2025-07-26T08:18:48.453401"
}