{
  "ptid_time": "137_S_4862_2013-07-22",
  "img_path": "/data/qiuhui/data/adni/images/137_S_4862/2013-07-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 33,499 mm³, 13.0% below the reference mean. With a Z-score of -0.31 (37.7th percentile), this represents normal volume ; hippocampal volume measures 7,546 mm³, 0.2% below the reference mean. With a Z-score of -0.02 (49.3th percentile), this represents normal volume ; whole brain volume measures 1,108,700 mm³, 2.7% above the reference mean. With a Z-score of 0.35 (63.8th percentile), this represents normal volume ; entorhinal cortex volume measures 3,798 mm³, 7.4% below the reference mean. With a Z-score of -0.50 (30.8th percentile), this represents normal volume ; fusiform gyrus volume measures 22,116 mm³, 17.4% above the reference mean. With a Z-score of 1.48 (93.1th percentile), this represents mild enlargement; middle temporal gyrus volume measures 23,202 mm³, 8.7% above the reference mean. With a Z-score of 0.78 (78.4th percentile), this represents normal volume . ",
  "text_data": "Age is 77.3 years. Gender is Male. Education: 18 years. Medical history: Head, Eyes, Ears, Nose and Throat; Musculoskeletal; Renal-Genitourinary; Malignancy; Major Surgical Procedures. MMSE: 29.0. MoCA: 23.0. Logical Memory: 11.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.54 SUVR (profound elevated); Amyloid beta: 751.00 pg/mL (normal ); Total tau: 398.90 pg/mL (significant elevated); Phosphorylated tau: 39.60 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volumes are largely within normal ranges, with only mild deviations (e.g., fusiform gyrus enlargement). However, the clinical markers show significant abnormalities: elevated T-tau and P-tau (indicative of neurodegeneration) and profoundly elevated AV45 (suggesting amyloid pathology). The MoCA score of 23 is borderline for MCI, while the MMSE of 29 is normal.  \nDiagnosis: MCI (likely prodromal Alzheimer's due to biomarker profile)  \nConfidence: Medium (biomarkers strongly suggest neurodegeneration, but cognitive scores are not yet fully consistent",
  "timestamp": "2025-07-26T16:45:39.203311"
}