{
  "ptid_time": "137_S_4587_2012-07-24",
  "img_path": "/data/qiuhui/data/adni/images/137_S_4587/2012-07-24/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 37,616 mm³, 68.4% above the reference mean. With a Z-score of 1.71 (95.7th percentile), this represents moderate enlargement; hippocampal volume measures 8,216 mm³, 6.9% above the reference mean. With a Z-score of 0.78 (78.1th percentile), this represents normal volume ; whole brain volume measures 948,641 mm³, 7.8% below the reference mean. With a Z-score of -0.97 (16.5th percentile), this represents normal volume ; entorhinal cortex volume measures 3,368 mm³, 13.5% below the reference mean. With a Z-score of -1.04 (14.8th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,915 mm³, 1.6% below the reference mean. With a Z-score of -0.18 (42.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,355 mm³, 0.8% below the reference mean. With a Z-score of -0.07 (47.2th percentile), this represents normal volume . ",
  "text_data": "Age is 65.7 years. Gender is Female. Education: 16 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Endocrine-Metabolic; Major Surgical Procedures. MMSE: 29.0. MoCA: 29.0. Logical Memory: 12.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.30 SUVR (moderate elevated); Amyloid beta: 686.40 pg/mL (normal ); Total tau: 253.60 pg/mL (normal ); Phosphorylated tau: 24.38 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular enlargement and mild entorhinal cortex atrophy, but hippocampal and whole brain volumes are within normal ranges. Cognitive scores (MMSE, MoCA) are high, and biomarkers (Aβ, T-tau, P-tau) are normal, though AV45 (amyloid PET) is moderately elevated, suggesting early amyloid deposition.  \n**Diagnosis:** **MCI** (due to structural changes and amyloid positivity despite normal cognition)  \n**Confidence:** **Medium** (conflicting markers—normal biomarkers vs. AV45 elevation and mild atrophy)",
  "timestamp": "2025-07-26T16:36:37.641702"
}