{
  "ptid_time": "136_S_0695_2010-11-16",
  "img_path": "/data/qiuhui/data/adni/images/136_S_0695/2010-11-16/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 5,502 mm³, 27.2% below the reference mean. With a Z-score of -2.65 (0.4th percentile), this represents significant atrophy; whole brain volume measures 1,006,970 mm³, 6.7% below the reference mean. With a Z-score of -0.87 (19.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,887 mm³, 29.6% below the reference mean. With a Z-score of -2.01 (2.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,482 mm³, 17.8% below the reference mean. With a Z-score of -1.52 (6.5th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 12,249 mm³, 42.6% below the reference mean. With a Z-score of -3.83 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 78.3 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Musculoskeletal; Major Surgical Procedures. MMSE: 9.0. MoCA: 1.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits profound atrophy in key Alzheimer’s-related regions (hippocampus, entorhinal cortex, middle temporal gyrus) alongside severe cognitive impairment (MMSE 9, MoCA 1), strongly suggesting neurodegenerative disease. The APOE4 carrier status further supports Alzheimer’s pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T16:03:41.175597"
}