{
  "ptid_time": "130_S_0232_2006-09-05",
  "img_path": "/data/qiuhui/data/adni/images/130_S_0232/2006-09-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 43,174 mm³, 12.1% above the reference mean. With a Z-score of 0.29 (61.4th percentile), this represents normal volume ; hippocampal volume measures 7,504 mm³, 0.7% below the reference mean. With a Z-score of -0.07 (47.2th percentile), this represents normal volume ; whole brain volume measures 1,099,620 mm³, 1.9% above the reference mean. With a Z-score of 0.24 (59.6th percentile), this represents normal volume ; entorhinal cortex volume measures 3,602 mm³, 12.2% below the reference mean. With a Z-score of -0.82 (20.5th percentile), this represents normal volume ; fusiform gyrus volume measures 22,541 mm³, 19.7% above the reference mean. With a Z-score of 1.67 (95.3th percentile), this represents moderate enlargement; middle temporal gyrus volume measures 23,328 mm³, 9.3% above the reference mean. With a Z-score of 0.84 (79.9th percentile), this represents normal volume . ",
  "text_data": "Age is 78.5 years. Gender is Male. Education: 20 years. MMSE: 30.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges, with only the entorhinal cortex showing a slight reduction (12.2% below mean, Z-score -0.82) but still classified as normal. The fusiform gyrus shows moderate enlargement, but this is not typically associated with Alzheimer's pathology. The MMSE score of 30/30 is intact, and the absence of APOE4 alleles reduces genetic risk. No significant atrophy or cognitive impairment is evident.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T14:22:56.737288"
}