{
  "ptid_time": "100_S_1226_2010-03-16",
  "img_path": "/data/qiuhui/data/adni/images/100_S_1226/2010-03-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 59,796 mm³, 27.2% above the reference mean. With a Z-score of 0.79 (78.5th percentile), this represents normal volume ; hippocampal volume measures 5,576 mm³, 20.0% below the reference mean. With a Z-score of -1.73 (4.2th percentile), this represents moderate atrophy; whole brain volume measures 1,007,010 mm³, 2.2% below the reference mean. With a Z-score of -0.28 (38.9th percentile), this represents normal volume ; entorhinal cortex volume measures 3,252 mm³, 18.1% below the reference mean. With a Z-score of -1.18 (11.8th percentile), this represents mild atrophy; fusiform gyrus volume measures 15,161 mm³, 16.1% below the reference mean. With a Z-score of -1.39 (8.2th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,448 mm³, 18.5% below the reference mean. With a Z-score of -1.65 (4.9th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 85.6 years. Gender is Male. Education: 16 years. MMSE: 28.0. Logical Memory: 4.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows moderate atrophy (Z-score -1.73, 4.2th percentile), and other regions (entorhinal cortex, fusiform gyrus, middle temporal gyrus) also exhibit mild to moderate atrophy. However, the MMSE score of 28 is within the normal range, and there is no APOE4 risk allele.  \n**Diagnosis:** Mild Cognitive Impairment (MCI)  \n**Confidence:** Medium  \n\n*(Note: The high MMSE suggests preserved cognition despite structural changes, making dementia less likely. However, significant atrophy in memory-related regions raises concern for MCI. Confidence is medium due to the lack of cognitive symptoms but clear structural decline.)*",
  "timestamp": "2025-07-26T11:22:34.081755"
}