{
  "ptid_time": "041_S_1412_2008-07-28",
  "img_path": "/data/qiuhui/data/adni/images/041_S_1412/2008-07-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 71,972 mm³, 139.7% above the reference mean. With a Z-score of 3.32 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,645 mm³, 17.2% below the reference mean. With a Z-score of -1.72 (4.3th percentile), this represents moderate atrophy; whole brain volume measures 1,312,930 mm³, 15.7% above the reference mean. With a Z-score of 2.23 (98.7th percentile), this represents significant enlargement; entorhinal cortex volume measures 3,857 mm³, 9.5% below the reference mean. With a Z-score of -0.66 (25.5th percentile), this represents normal volume ; fusiform gyrus volume measures 20,133 mm³, 1.1% above the reference mean. With a Z-score of 0.09 (53.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,857 mm³, 10.9% above the reference mean. With a Z-score of 0.90 (81.6th percentile), this represents normal volume . ",
  "text_data": "Age is 60.4 years. Gender is Male. Education: 16 years. MMSE: 25.0. Logical Memory: 4.0. APOEε4 alleles: 1.0. Biomarker levels: Pittsburgh compound B: 2.04 SUVR (mild elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The data shows profound ventricular enlargement (Z-score 3.32) and moderate hippocampal atrophy (Z-score -1.72), both of which are strong indicators of neurodegeneration. The MMSE score of 25 is borderline, but the structural changes suggest cognitive impairment beyond normal aging.  \nDiagnosis: MCI (Mild Cognitive Impairment)  \nConfidence: Medium  \n\n(Note: The diagnosis is MCI rather than dementia due to the absence of severe functional decline, but the significant hippocampal atrophy and ventricular enlargement raise concern for progression. The confidence is medium because while the imaging strongly suggests pathology, the MMSE is only mildly reduced, and clinical correlation with daily functioning would help clarify severity.)",
  "timestamp": "2025-07-26T07:05:45.231494"
}