{
  "ptid_time": "023_S_1247_2008-08-12",
  "img_path": "/data/qiuhui/data/adni/images/023_S_1247/2008-08-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,170 mm³, 64.5% above the reference mean. With a Z-score of 1.48 (93.0th percentile), this represents mild enlargement; hippocampal volume measures 5,617 mm³, 21.0% below the reference mean. With a Z-score of -1.93 (2.7th percentile), this represents moderate atrophy; whole brain volume measures 858,341 mm³, 11.9% below the reference mean. With a Z-score of -1.50 (6.7th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,701 mm³, 26.5% below the reference mean. With a Z-score of -1.62 (5.2th percentile), this represents moderate atrophy; fusiform gyrus volume measures 14,232 mm³, 16.3% below the reference mean. With a Z-score of -1.49 (6.8th percentile), this represents mild atrophy; middle temporal gyrus volume measures 15,425 mm³, 19.5% below the reference mean. With a Z-score of -1.70 (4.5th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 74.0 years. Gender is Female. Education: 9 years. MMSE: 23.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, middle temporal gyrus) alongside mild-to-moderate whole-brain atrophy. The MMSE score of 23 suggests cognitive impairment, but without APOE4 and with only moderate hippocampal atrophy, the progression may not be as rapid.  \n**Diagnosis:** Mild Cognitive Impairment (MCI)  \n**Confidence:** Medium",
  "timestamp": "2025-07-26T02:57:16.891073"
}