{
  "ptid_time": "094_S_1398_2008-12-01",
  "img_path": "/data/qiuhui/data/adni/images/094_S_1398/2008-12-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,327 mm³, 75.7% above the reference mean. With a Z-score of 1.73 (95.9th percentile), this represents moderate enlargement; hippocampal volume measures 3,105 mm³, 56.4% below the reference mean. With a Z-score of -5.17 (0.0th percentile), this represents profound atrophy; whole brain volume measures 649,091 mm³, 33.4% below the reference mean. With a Z-score of -4.20 (0.0th percentile), this represents profound atrophy; entorhinal cortex volume measures 1,236 mm³, 66.3% below the reference mean. With a Z-score of -4.07 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,824 mm³, 30.5% below the reference mean. With a Z-score of -2.78 (0.3th percentile), this represents significant atrophy; middle temporal gyrus volume measures 11,913 mm³, 37.9% below the reference mean. With a Z-score of -3.29 (0.1th percentile), this represents profound atrophy. ",
  "text_data": "Age is 79.1 years. Gender is Female. Education: 16 years. MMSE: 15.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, middle temporal gyrus) and significant whole-brain volume loss, consistent with advanced neurodegeneration. The MMSE score of 15 indicates severe cognitive impairment, aligning with the structural findings.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given APOE4 positivity and atrophy pattern).  \n\n**Confidence:** **High** (severe atrophy, low MMSE, and APOE4 support a clear dementia diagnosis).",
  "timestamp": "2025-07-26T10:23:39.310552"
}