{
  "ptid_time": "041_S_0314_2007-05-02",
  "img_path": "/data/qiuhui/data/adni/images/041_S_0314/2007-05-02/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 35,453 mm³, 8.0% below the reference mean. With a Z-score of -0.19 (42.4th percentile), this represents normal volume ; hippocampal volume measures 6,395 mm³, 15.4% below the reference mean. With a Z-score of -1.50 (6.7th percentile), this represents moderate atrophy; whole brain volume measures 1,076,600 mm³, 0.3% below the reference mean. With a Z-score of -0.03 (48.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,015 mm³, 26.5% below the reference mean. With a Z-score of -1.80 (3.6th percentile), this represents moderate atrophy; fusiform gyrus volume measures 19,551 mm³, 3.8% above the reference mean. With a Z-score of 0.32 (62.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,715 mm³, 7.6% below the reference mean. With a Z-score of -0.68 (24.7th percentile), this represents normal volume . ",
  "text_data": "Age is 72.6 years. Gender is Male. Education: 19 years. MMSE: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal and entorhinal cortex volumes show moderate atrophy (Z-scores of -1.50 and -1.80, respectively), which are key regions affected in Alzheimer's disease. The MMSE score of 23 suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment)**  \n**Confidence:** **Medium** (While structural atrophy and cognitive decline are present, additional biomarkers or longitudinal data would strengthen the diagnosis.)",
  "timestamp": "2025-07-26T06:57:33.862075"
}