{
  "ptid_time": "022_S_0750_2008-08-29",
  "img_path": "/data/qiuhui/data/adni/images/022_S_0750/2008-08-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 70,762 mm³, 152.1% above the reference mean. With a Z-score of 3.48 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,125 mm³, 28.0% below the reference mean. With a Z-score of -2.56 (0.5th percentile), this represents significant atrophy; whole brain volume measures 690,525 mm³, 29.2% below the reference mean. With a Z-score of -3.67 (0.0th percentile), this represents profound atrophy; entorhinal cortex volume measures 2,691 mm³, 26.7% below the reference mean. With a Z-score of -1.64 (5.0th percentile), this represents moderate atrophy; fusiform gyrus volume measures 10,418 mm³, 38.8% below the reference mean. With a Z-score of -3.53 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 8,876 mm³, 53.7% below the reference mean. With a Z-score of -4.66 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 77.6 years. Gender is Female. Education: 12 years. MMSE: 8.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in multiple brain regions, including the hippocampus, whole brain, fusiform gyrus, and middle temporal gyrus, along with significant ventricular enlargement. The MMSE score of 8 indicates severe cognitive impairment, and the presence of an APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given the hippocampal and temporal lobe atrophy).  \n\n**Confidence:** **High** (due to severe structural atrophy and very low MMSE score).",
  "timestamp": "2025-07-26T02:07:00.791900"
}