{
  "ptid_time": "073_S_0089_2006-01-26",
  "img_path": "/data/qiuhui/data/adni/images/073_S_0089/2006-01-26/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,339 mm³, 28.9% below the reference mean. With a Z-score of -0.69 (24.6th percentile), this represents normal volume ; hippocampal volume measures 7,713 mm³, 3.9% below the reference mean. With a Z-score of -0.39 (34.8th percentile), this represents normal volume ; whole brain volume measures 1,079,510 mm³, 4.9% below the reference mean. With a Z-score of -0.69 (24.6th percentile), this represents normal volume ; entorhinal cortex volume measures 4,468 mm³, 4.8% above the reference mean. With a Z-score of 0.33 (63.0th percentile), this represents normal volume ; fusiform gyrus volume measures 22,039 mm³, 10.7% above the reference mean. With a Z-score of 0.89 (81.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 23,962 mm³, 6.9% above the reference mean. With a Z-score of 0.57 (71.6th percentile), this represents normal volume . ",
  "text_data": "Age is 65.1 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Cardiovascular; Musculoskeletal; Gastrointestinal; Smoking; Major Surgical Procedures. MMSE: 30.0. Logical Memory: 11.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1414.00 pg/mL (mild elevated); Total tau: 158.90 pg/mL (mild reduced); Phosphorylated tau: 14.88 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** All brain volumes (ventricular, hippocampal, whole brain, entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges based on Z-scores and percentiles. The MMSE score of 30 is optimal, and while Aβ is mildly elevated, T-tau is mildly reduced, and P-tau is normal, these biomarker findings alone do not strongly suggest neurodegeneration.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mildly elevated Aβ, but no structural or cognitive deficits)",
  "timestamp": "2025-07-26T09:28:10.837602"
}