{
  "ptid_time": "005_S_0222_2007-10-05",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0222/2007-10-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,217 mm³, 4.7% above the reference mean. With a Z-score of 0.14 (55.4th percentile), this represents normal volume ; hippocampal volume measures 4,960 mm³, 28.8% below the reference mean. With a Z-score of -2.49 (0.6th percentile), this represents significant atrophy; whole brain volume measures 927,566 mm³, 9.9% below the reference mean. With a Z-score of -1.29 (9.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,446 mm³, 13.2% below the reference mean. With a Z-score of -0.86 (19.4th percentile), this represents normal volume ; fusiform gyrus volume measures 16,046 mm³, 11.2% below the reference mean. With a Z-score of -0.97 (16.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,098 mm³, 10.3% below the reference mean. With a Z-score of -0.92 (17.8th percentile), this represents normal volume . ",
  "text_data": "Age is 87.4 years. Gender is Male. Education: 18 years. MMSE: 24.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The hippocampal volume shows significant atrophy (Z-score -2.49, 0.6th percentile), which is a strong biomarker for Alzheimer's disease. The whole brain volume also shows mild atrophy, while other regions are within normal limits. The MMSE score of 24 is borderline for cognitive impairment, and the absence of APOE4 reduces genetic risk but does not rule out AD.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: Medium (due to significant hippocampal atrophy and borderline MMSE, but lack of APOE4 and normal volumes in other regions introduce some doubt).",
  "timestamp": "2025-07-25T21:03:20.217108"
}