{
  "ptid_time": "082_S_5029_2013-06-27",
  "img_path": "/data/qiuhui/data/adni/images/082_S_5029/2013-06-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,947 mm³, 4.1% above the reference mean. With a Z-score of 0.12 (54.7th percentile), this represents normal volume ; hippocampal volume measures 5,634 mm³, 19.1% below the reference mean. With a Z-score of -1.65 (4.9th percentile), this represents moderate atrophy; whole brain volume measures 1,145,510 mm³, 11.3% above the reference mean. With a Z-score of 1.48 (93.1th percentile), this represents mild enlargement; entorhinal cortex volume measures 2,692 mm³, 32.2% below the reference mean. With a Z-score of -2.11 (1.8th percentile), this represents significant atrophy; fusiform gyrus volume measures 18,393 mm³, 1.8% above the reference mean. With a Z-score of 0.16 (56.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,373 mm³, 8.9% below the reference mean. With a Z-score of -0.80 (21.2th percentile), this represents normal volume . ",
  "text_data": "Age is 80.1 years. Gender is Male. Education: 16 years. MMSE: 16.0. MoCA: 10.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant atrophy in the hippocampus and entorhinal cortex, both key regions affected in Alzheimer's disease, alongside cognitive scores (MMSE 16, MoCA 10) well below normal thresholds. The presence of two APOE4 alleles further increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T10:08:39.514827"
}