{
  "ptid_time": "005_S_0324_2006-03-30",
  "img_path": "/data/qiuhui/data/adni/images/005_S_0324/2006-03-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 16,034 mm³, 42.9% below the reference mean. With a Z-score of -0.98 (16.3th percentile), this represents normal volume ; hippocampal volume measures 4,671 mm³, 34.3% below the reference mean. With a Z-score of -3.15 (0.1th percentile), this represents profound atrophy; whole brain volume measures 863,624 mm³, 11.4% below the reference mean. With a Z-score of -1.43 (7.6th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,183 mm³, 40.6% below the reference mean. With a Z-score of -2.49 (0.6th percentile), this represents significant atrophy; fusiform gyrus volume measures 12,290 mm³, 27.8% below the reference mean. With a Z-score of -2.53 (0.6th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,612 mm³, 23.8% below the reference mean. With a Z-score of -2.06 (2.0th percentile), this represents significant atrophy. ",
  "text_data": "Age is 75.3 years. Gender is Female. Education: 14 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Malignancy; Major Surgical Procedures. MMSE: 24.0. Logical Memory: 1.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.15, 0.1th percentile) and significant atrophy in the entorhinal cortex, fusiform gyrus, and middle temporal gyrus, which are key regions affected in Alzheimer's disease. The MMSE score of 24 suggests mild cognitive impairment, and the absence of APOE4 does not rule out AD.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T21:04:27.704739"
}