{
  "ptid_time": "068_S_4340_2017-08-10",
  "img_path": "/data/qiuhui/data/adni/images/068_S_4340/2017-08-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 23,751 mm³, 15.4% below the reference mean. With a Z-score of -0.35 (36.2th percentile), this represents normal volume ; hippocampal volume measures 8,497 mm³, 19.4% above the reference mean. With a Z-score of 1.78 (96.3th percentile), this represents moderate enlargement; whole brain volume measures 1,167,180 mm³, 19.8% above the reference mean. With a Z-score of 2.49 (99.4th percentile), this represents significant enlargement; entorhinal cortex volume measures 4,362 mm³, 18.8% above the reference mean. With a Z-score of 1.15 (87.5th percentile), this represents mild enlargement; fusiform gyrus volume measures 25,152 mm³, 47.8% above the reference mean. With a Z-score of 4.35 (100.0th percentile), this represents profound enlargement; middle temporal gyrus volume measures 20,761 mm³, 8.3% above the reference mean. With a Z-score of 0.72 (76.4th percentile), this represents normal volume . ",
  "text_data": "Age is 72.2 years. Gender is Female. Education: 16 years. MMSE: 29.0. MoCA: 30.0. Logical Memory: 16.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The volumetric data shows significant enlargement in multiple brain regions (hippocampus, whole brain, entorhinal cortex, fusiform gyrus) with no atrophy, which is atypical for Alzheimer's disease. Cognitive scores (MMSE 29, MoCA 30) are in the normal range, and the absence of APOE4 further reduces Alzheimer's risk.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T09:01:54.612684"
}