{
  "ptid_time": "057_S_1373_2007-10-17",
  "img_path": "/data/qiuhui/data/adni/images/057_S_1373/2007-10-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 81,763 mm³, 112.3% above the reference mean. With a Z-score of 2.69 (99.6th percentile), this represents significant enlargement; hippocampal volume measures 4,075 mm³, 46.1% below the reference mean. With a Z-score of -4.50 (0.0th percentile), this represents profound atrophy; whole brain volume measures 793,031 mm³, 26.5% below the reference mean. With a Z-score of -3.44 (0.0th percentile), this represents profound atrophy; entorhinal cortex volume measures 2,039 mm³, 50.3% below the reference mean. With a Z-score of -3.41 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 9,828 mm³, 47.8% below the reference mean. With a Z-score of -4.07 (0.0th percentile), this represents profound atrophy; middle temporal gyrus volume measures 9,132 mm³, 57.2% below the reference mean. With a Z-score of -5.14 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 75.9 years. Gender is Male. Education: 20 years. MMSE: 18.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in multiple brain regions critical for memory and cognition (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus) alongside significant ventricular enlargement, consistent with advanced neurodegeneration. The MMSE score of 18 indicates severe cognitive impairment, and the presence of an APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T08:12:03.787636"
}