{
  "ptid_time": "098_S_0171_2006-07-30",
  "img_path": "/data/qiuhui/data/adni/images/098_S_0171/2006-07-30/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 60,189 mm³, 114.4% above the reference mean. With a Z-score of 2.62 (99.6th percentile), this represents significant enlargement; hippocampal volume measures 6,685 mm³, 6.0% below the reference mean. With a Z-score of -0.55 (29.0th percentile), this represents normal volume ; whole brain volume measures 882,920 mm³, 9.4% below the reference mean. With a Z-score of -1.18 (11.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,449 mm³, 6.1% below the reference mean. With a Z-score of -0.37 (35.4th percentile), this represents normal volume ; fusiform gyrus volume measures 14,611 mm³, 14.1% below the reference mean. With a Z-score of -1.28 (9.9th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,965 mm³, 11.5% below the reference mean. With a Z-score of -1.00 (15.9th percentile), this represents normal volume . ",
  "text_data": "Age is 78.8 years. Gender is Female. Education: 17 years. MMSE: 28.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 2.62) and mild whole brain atrophy (Z-score -1.18), along with mild fusiform gyrus atrophy (Z-score -1.28), which are concerning for neurodegenerative changes. However, hippocampal and entorhinal cortex volumes are within normal limits, and the MMSE score of 28 is intact, suggesting preserved cognitive function. The absence of APOE4 reduces genetic risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural changes suggest early neurodegeneration, but cognitive performance remains intact, making dementia unlikely at this stage.)",
  "timestamp": "2025-07-26T10:37:35.994996"
}