{
  "ptid_time": "014_S_0169_2010-02-04",
  "img_path": "/data/qiuhui/data/adni/images/014_S_0169/2010-02-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 47,578 mm³, 69.5% above the reference mean. With a Z-score of 1.59 (94.4th percentile), this represents moderate enlargement; hippocampal volume measures 6,751 mm³, 5.1% below the reference mean. With a Z-score of -0.47 (32.0th percentile), this represents normal volume ; whole brain volume measures 979,988 mm³, 0.5% above the reference mean. With a Z-score of 0.07 (52.7th percentile), this represents normal volume ; entorhinal cortex volume measures 2,921 mm³, 20.5% below the reference mean. With a Z-score of -1.26 (10.4th percentile), this represents mild atrophy; fusiform gyrus volume measures 13,791 mm³, 18.9% below the reference mean. With a Z-score of -1.72 (4.2th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 18,101 mm³, 5.6% below the reference mean. With a Z-score of -0.48 (31.4th percentile), this represents normal volume . ",
  "text_data": "Age is 75.9 years. Gender is Female. Education: 16 years. MMSE: 28.0. Logical Memory: 10.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows moderate ventricular enlargement and mild-to-moderate atrophy in the entorhinal cortex and fusiform gyrus, regions critical for memory and cognition. However, hippocampal volume is normal, and MMSE score (28/30) is within the normal range, suggesting no significant cognitive impairment. The presence of one APOE4 allele increases Alzheimer's risk but does not confirm pathology.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to conflicting structural findings—some atrophy but preserved cognition and hippocampal volume)",
  "timestamp": "2025-07-25T23:39:10.898013"
}