{
  "ptid_time": "027_S_1385_2007-09-19",
  "img_path": "/data/qiuhui/data/adni/images/027_S_1385/2007-09-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 13,259 mm³, 52.8% below the reference mean. With a Z-score of -1.21 (11.3th percentile), this represents mild atrophy; hippocampal volume measures 4,510 mm³, 36.6% below the reference mean. With a Z-score of -3.36 (0.0th percentile), this represents profound atrophy; whole brain volume measures 869,733 mm³, 10.8% below the reference mean. With a Z-score of -1.36 (8.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,413 mm³, 7.1% below the reference mean. With a Z-score of -0.43 (33.2th percentile), this represents normal volume ; fusiform gyrus volume measures 12,822 mm³, 24.6% below the reference mean. With a Z-score of -2.24 (1.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 15,100 mm³, 21.2% below the reference mean. With a Z-score of -1.84 (3.3th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 70.0 years. Gender is Female. Education: 12 years. MMSE: 23.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits profound hippocampal atrophy (Z-score -3.36, 0.0th percentile) and significant atrophy in the fusiform gyrus (Z-score -2.24, 1.2th percentile), both strongly associated with Alzheimer's pathology. The MMSE score of 23 suggests cognitive impairment, and the presence of two APOE4 alleles increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T03:49:38.687398"
}