{
  "ptid_time": "036_S_0577_2007-06-06",
  "img_path": "/data/qiuhui/data/adni/images/036_S_0577/2007-06-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 24,682 mm³, 12.1% below the reference mean. With a Z-score of -0.28 (39.1th percentile), this represents normal volume ; hippocampal volume measures 4,065 mm³, 42.9% below the reference mean. With a Z-score of -3.93 (0.0th percentile), this represents profound atrophy; whole brain volume measures 861,855 mm³, 11.6% below the reference mean. With a Z-score of -1.46 (7.3th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,821 mm³, 50.4% below the reference mean. With a Z-score of -3.09 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 12,275 mm³, 27.8% below the reference mean. With a Z-score of -2.53 (0.6th percentile), this represents significant atrophy; middle temporal gyrus volume measures 14,156 mm³, 26.2% below the reference mean. With a Z-score of -2.27 (1.2th percentile), this represents significant atrophy. ",
  "text_data": "Age is 73.4 years. Gender is Female. Education: 12 years. MMSE: 19.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Amyloid beta: 602.60 pg/mL (mild reduced); Total tau: 557.40 pg/mL (profound elevated); Phosphorylated tau: 51.91 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The patient shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). Elevated T-tau and P-tau levels, along with reduced Aβ, strongly support AD pathology. The MMSE score of 19 indicates significant cognitive impairment.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: High",
  "timestamp": "2025-07-26T06:01:42.633216"
}