{
  "ptid_time": "033_S_5087_2013-09-06",
  "img_path": "/data/qiuhui/data/adni/images/033_S_5087/2013-09-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 61,151 mm³, 173.8% above the reference mean. With a Z-score of 4.35 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,132 mm³, 20.2% below the reference mean. With a Z-score of -2.27 (1.2th percentile), this represents significant atrophy; whole brain volume measures 961,923 mm³, 6.5% below the reference mean. With a Z-score of -0.81 (20.8th percentile), this represents normal volume ; entorhinal cortex volume measures 2,686 mm³, 31.0% below the reference mean. With a Z-score of -2.40 (0.8th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,485 mm³, 15.0% below the reference mean. With a Z-score of -1.69 (4.6th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 16,827 mm³, 18.0% below the reference mean. With a Z-score of -1.60 (5.5th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 65.1 years. Gender is Female. Education: 17 years. MMSE: 24.0. MoCA: 16.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease, along with moderate atrophy in the fusiform gyrus and middle temporal gyrus. The MMSE (24) and MoCA (16) scores indicate cognitive impairment, and the absence of APOE4 does not rule out AD. Ventricular enlargement further supports neurodegeneration.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T05:38:15.334961"
}