{
  "ptid_time": "005_S_4707_2013-06-18",
  "img_path": "/data/qiuhui/data/adni/images/005_S_4707/2013-06-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 59,611 mm³, 98.5% above the reference mean. With a Z-score of 2.34 (99.0th percentile), this represents significant enlargement; hippocampal volume measures 5,476 mm³, 31.8% below the reference mean. With a Z-score of -3.18 (0.1th percentile), this represents profound atrophy; whole brain volume measures 1,025,700 mm³, 9.6% below the reference mean. With a Z-score of -1.36 (8.7th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,323 mm³, 22.0% below the reference mean. With a Z-score of -1.53 (6.4th percentile), this represents moderate atrophy; fusiform gyrus volume measures 18,444 mm³, 7.4% below the reference mean. With a Z-score of -0.61 (27.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,838 mm³, 24.9% below the reference mean. With a Z-score of -2.05 (2.0th percentile), this represents significant atrophy. ",
  "text_data": "Age is 69.0 years. Gender is Male. Education: 14 years. MMSE: 18.0. MoCA: 12.0. Logical Memory: 3.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant hippocampal atrophy (Z-score -3.18, 0.1th percentile) and moderate-to-severe atrophy in other key regions (entorhinal cortex, middle temporal gyrus), alongside marked ventricular enlargement, consistent with neurodegeneration. The cognitive scores (MMSE 18, MoCA 12) indicate severe impairment, and the presence of an APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T21:23:57.177233"
}