{
  "ptid_time": "135_S_6840_2019-12-05",
  "img_path": "/data/qiuhui/data/adni/images/135_S_6840/2019-12-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,749 mm³, 100.3% above the reference mean. With a Z-score of 2.51 (99.4th percentile), this represents significant enlargement; hippocampal volume measures 5,369 mm³, 30.1% below the reference mean. With a Z-score of -3.38 (0.0th percentile), this represents profound atrophy; whole brain volume measures 961,158 mm³, 6.6% below the reference mean. With a Z-score of -0.82 (20.5th percentile), this represents normal volume ; entorhinal cortex volume measures 1,922 mm³, 50.6% below the reference mean. With a Z-score of -3.92 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 15,653 mm³, 14.0% below the reference mean. With a Z-score of -1.58 (5.7th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 18,296 mm³, 10.8% below the reference mean. With a Z-score of -0.96 (16.8th percentile), this represents normal volume . ",
  "text_data": "Age is 68.6 years. Gender is Female. Education: 12 years. Handedness: Right. Race: White. MMSE: 28.0. MoCA: 22.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Flobetaben (FBB): 1.79 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The imaging shows significant hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD). The MoCA score of 22 suggests mild cognitive impairment, while the MMSE of 28 is borderline normal, indicating possible early-stage cognitive decline. The presence of two APOE4 alleles further increases AD risk.  \nDiagnosis: MCI (likely due to Alzheimer's pathology)  \nConfidence: High",
  "timestamp": "2025-07-26T15:54:26.971086"
}