{
  "ptid_time": "130_S_4925_2013-04-19",
  "img_path": "/data/qiuhui/data/adni/images/130_S_4925/2013-04-19/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 82,757 mm³, 114.9% above the reference mean. With a Z-score of 2.75 (99.7th percentile), this represents significant enlargement; hippocampal volume measures 6,618 mm³, 12.5% below the reference mean. With a Z-score of -1.21 (11.2th percentile), this represents mild atrophy; whole brain volume measures 1,086,130 mm³, 0.6% above the reference mean. With a Z-score of 0.08 (53.2th percentile), this represents normal volume ; entorhinal cortex volume measures 3,634 mm³, 11.4% below the reference mean. With a Z-score of -0.77 (22.0th percentile), this represents normal volume ; fusiform gyrus volume measures 17,854 mm³, 5.2% below the reference mean. With a Z-score of -0.45 (32.8th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,700 mm³, 7.7% below the reference mean. With a Z-score of -0.69 (24.5th percentile), this represents normal volume . ",
  "text_data": "Age is 75.5 years. Gender is Male. Education: 12 years. MMSE: 19.0. MoCA: 19.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 2.75) and mild hippocampal atrophy (Z-score -1.21), both of which are associated with neurodegenerative processes. The cognitive scores (MMSE and MoCA both at 19) are below normal ranges, suggesting cognitive impairment. The absence of APOE4 does not rule out dementia, as structural and cognitive findings are more indicative.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given hippocampal atrophy and ventricular enlargement, though other etiologies should be considered).  \n\n**Confidence:** **High** (due to clear structural and cognitive deficits, though neuroimaging or CSF biomarkers could further confirm).",
  "timestamp": "2025-07-26T14:53:52.993683"
}