{
  "ptid_time": "029_S_4307_2012-08-16",
  "img_path": "/data/qiuhui/data/adni/images/029_S_4307/2012-08-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 95,816 mm³, 148.8% above the reference mean. With a Z-score of 3.56 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,474 mm³, 40.8% below the reference mean. With a Z-score of -3.98 (0.0th percentile), this represents profound atrophy; whole brain volume measures 984,338 mm³, 8.8% below the reference mean. With a Z-score of -1.14 (12.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 79.0 years. Gender is Male. Education: 16 years. MMSE: 21.0. MoCA: 16.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal atrophy (Z-score -3.98) and severe ventricular enlargement (Z-score 3.56), both strong indicators of neurodegeneration. Combined with cognitive test scores (MMSE 21, MoCA 16) below typical cutoffs for dementia, this strongly suggests significant cognitive impairment.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease given hippocampal atrophy and APOE4 positivity).  \n\n**Confidence:** **High** (due to clear structural and cognitive deficits consistent with dementia).",
  "timestamp": "2025-07-26T04:27:59.722752"
}