{
  "ptid_time": "016_S_0769_2009-08-24",
  "img_path": "/data/qiuhui/data/adni/images/016_S_0769/2009-08-24/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 121,125 mm³, 303.4% above the reference mean. With a Z-score of 7.21 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,283 mm³, 34.2% below the reference mean. With a Z-score of -3.42 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,112,090 mm³, 2.0% below the reference mean. With a Z-score of -0.28 (39.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,137 mm³, 49.9% below the reference mean. With a Z-score of -3.45 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 17,459 mm³, 12.3% below the reference mean. With a Z-score of -1.02 (15.3th percentile), this represents mild atrophy; middle temporal gyrus volume measures 19,396 mm³, 13.5% below the reference mean. With a Z-score of -1.11 (13.4th percentile), this represents mild atrophy. ",
  "text_data": "Age is 65.2 years. Gender is Male. Education: 18 years. MMSE: 23.0. Logical Memory: 4.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD). Ventricular enlargement further supports neurodegeneration, while the MMSE score of 23 indicates cognitive impairment. The absence of APOE4 does not rule out AD, as sporadic cases are common.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T00:10:16.225185"
}