{
  "ptid_time": "016_S_1326_2007-09-28",
  "img_path": "/data/qiuhui/data/adni/images/016_S_1326/2007-09-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 52,871 mm³, 76.1% above the reference mean. With a Z-score of 1.81 (96.5th percentile), this represents moderate enlargement; hippocampal volume measures 7,543 mm³, 6.0% below the reference mean. With a Z-score of -0.60 (27.3th percentile), this represents normal volume ; whole brain volume measures 1,199,780 mm³, 5.8% above the reference mean. With a Z-score of 0.81 (79.2th percentile), this represents normal volume ; entorhinal cortex volume measures 3,083 mm³, 27.7% below the reference mean. With a Z-score of -1.92 (2.8th percentile), this represents moderate atrophy; fusiform gyrus volume measures 20,426 mm³, 2.6% above the reference mean. With a Z-score of 0.22 (58.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,856 mm³, 10.9% above the reference mean. With a Z-score of 0.90 (81.6th percentile), this represents normal volume . ",
  "text_data": "Age is 66.8 years. Gender is Male. Education: 18 years. MMSE: 29.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular enlargement and significant entorhinal cortex atrophy (Z-score -1.92, 2.8th percentile), which are concerning for early neurodegenerative changes. However, hippocampal volume is normal, and MMSE is intact (29/30), suggesting no significant cognitive impairment at this stage.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural changes are present, but cognitive performance remains largely intact, making early MCI more likely than dementia. APOE4 carrier status increases risk but does not confirm progression.)",
  "timestamp": "2025-07-26T00:18:22.305321"
}