{
  "ptid_time": "082_S_5184_2013-05-22",
  "img_path": "/data/qiuhui/data/adni/images/082_S_5184/2013-05-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 24,473 mm³, 12.8% below the reference mean. With a Z-score of -0.29 (38.5th percentile), this represents normal volume ; hippocampal volume measures 5,217 mm³, 26.7% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy; whole brain volume measures 909,415 mm³, 6.7% below the reference mean. With a Z-score of -0.84 (20.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,928 mm³, 20.3% below the reference mean. With a Z-score of -1.24 (10.7th percentile), this represents mild atrophy; fusiform gyrus volume measures 13,254 mm³, 22.1% below the reference mean. With a Z-score of -2.01 (2.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 15,569 mm³, 18.8% below the reference mean. With a Z-score of -1.63 (5.2th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 72.5 years. Gender is Female. Education: 17 years. Handedness: Right. Race: White. Medical history: Psychiatric; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Major Surgical Procedures. MMSE: 26.0. MoCA: 18.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.70 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus and fusiform gyrus, along with moderate atrophy in the middle temporal gyrus and mild atrophy in the entorhinal cortex—key regions affected in Alzheimer’s disease. The clinical profile (low MoCA score, APOE4 homozygosity, and elevated AV45 amyloid PET) strongly supports neurodegenerative pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T10:08:47.267455"
}