{
  "ptid_time": "012_S_6073_2017-09-22",
  "img_path": "/data/qiuhui/data/adni/images/012_S_6073/2017-09-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 79,725 mm³, 165.5% above the reference mean. With a Z-score of 3.93 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 7,773 mm³, 3.2% below the reference mean. With a Z-score of -0.32 (37.6th percentile), this represents normal volume ; whole brain volume measures 1,153,130 mm³, 1.6% above the reference mean. With a Z-score of 0.23 (59.2th percentile), this represents normal volume ; entorhinal cortex volume measures 4,829 mm³, 13.3% above the reference mean. With a Z-score of 0.92 (82.1th percentile), this represents normal volume ; fusiform gyrus volume measures 21,310 mm³, 7.0% above the reference mean. With a Z-score of 0.59 (72.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,615 mm³, 8.0% below the reference mean. With a Z-score of -0.66 (25.5th percentile), this represents normal volume . ",
  "text_data": "Age is 62.9 years. Gender is Male. Education: 17 years. Handedness: Left. Race: White. MMSE: 26.0. MoCA: 19.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.52 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.93), which is strongly suggestive of significant brain atrophy, particularly in the context of a mildly impaired MMSE (26) and a more notably impaired MoCA (19). The hippocampal volume is within normal limits, but the cognitive scores and ventricular enlargement raise concerns for neurodegenerative disease. The absence of APOE4 and elevated AV45 (amyloid PET) suggests possible non-Alzheimer’s pathology or mixed etiology.  \n\n**Diagnosis:** **Dementia** (likely non-Alzheimer’s or mixed etiology given the discrepancy between amyloid status and structural changes)  \n**Confidence:** **Medium** (cognitive scores and ventricular enlargement strongly suggest dementia, but the normal hippocampal volume and lack of APOE4 introduce some uncertainty about the underlying cause).",
  "timestamp": "2025-07-25T23:19:10.478674"
}