{
  "ptid_time": "941_S_4187_2011-06-22",
  "img_path": "/data/qiuhui/data/adni/images/941_S_4187/2011-06-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,042 mm³, 53.2% below the reference mean. With a Z-score of -1.26 (10.3th percentile), this represents mild atrophy; hippocampal volume measures 8,628 mm³, 7.5% above the reference mean. With a Z-score of 0.75 (77.3th percentile), this represents normal volume ; whole brain volume measures 1,302,060 mm³, 14.8% above the reference mean. With a Z-score of 2.09 (98.2th percentile), this represents significant enlargement; entorhinal cortex volume measures 4,348 mm³, 2.0% above the reference mean. With a Z-score of 0.14 (55.5th percentile), this represents normal volume ; fusiform gyrus volume measures 26,280 mm³, 32.0% above the reference mean. With a Z-score of 2.66 (99.6th percentile), this represents significant enlargement; middle temporal gyrus volume measures 25,243 mm³, 12.6% above the reference mean. With a Z-score of 1.04 (85.1th percentile), this represents mild enlargement. ",
  "text_data": "Age is 62.0 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Musculoskeletal; Major Surgical Procedures. MMSE: 29.0. MoCA: 22.0. Logical Memory: 6.0. Laboratory findings: MCHC: 36.00 (significant elevated); Total Bilirubin: 0.80 (significant elevated); Triglycerides (GPO): 250.00 (significant elevated); Creatinine (Rate Blanked): 1.40 (significant elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.03 SUVR (normal ); Amyloid beta: 963.70 pg/mL (normal ); Total tau: 212.00 pg/mL (normal ); Phosphorylated tau: 18.85 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain imaging shows mild ventricular atrophy but otherwise normal or enlarged volumes in key regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus). Biomarkers (Aβ, tau, AV45) are normal, and cognitive scores are mixed (MMSE 29 normal, MoCA 22 borderline). No APOE4 risk allele is present.  \n**Diagnosis:** **MCI** (due to borderline MoCA and mild ventricular atrophy, but no clear dementia profile).  \n**Confidence:** **Medium** (cognitive scores are conflicting, and structural changes are mild/atypical for neurodegener",
  "timestamp": "2025-07-26T17:35:00.001475"
}