{
  "ptid_time": "114_S_1118_2012-02-24",
  "img_path": "/data/qiuhui/data/adni/images/114_S_1118/2012-02-24/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 5,143 mm³, 26.2% below the reference mean. With a Z-score of -2.26 (1.2th percentile), this represents significant atrophy; whole brain volume measures 829,508 mm³, 19.4% below the reference mean. With a Z-score of -2.54 (0.6th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,073 mm³, 47.8% below the reference mean. With a Z-score of -3.13 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 14,297 mm³, 20.9% below the reference mean. With a Z-score of -1.81 (3.5th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,660 mm³, 22.4% below the reference mean. With a Z-score of -2.00 (2.2th percentile), this represents significant atrophy. ",
  "text_data": "Age is 87.5 years. Gender is Male. Education: 12 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Dermatologic-Connective Tissue; Endocrine-Metabolic; Major Surgical Procedures. MMSE: 24.0. MoCA: 18.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 0.99 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits significant atrophy in multiple brain regions, particularly the hippocampus and entorhinal cortex, which are strongly associated with Alzheimer's disease. The cognitive scores (MMSE 24, MoCA 18) suggest mild cognitive impairment, but the profound atrophy and normal AV45 (amyloid PET) may indicate non-amyloid pathology or advanced neurodegeneration.  \n\n**Diagnosis:** Dementia (likely neurodegenerative, possibly non-Alzheimer’s given normal AV45)  \n**Confidence:** Medium (clinical correlation needed to rule out other causes like vascular or Lewy body dementia)",
  "timestamp": "2025-07-26T11:45:36.247233"
}