{
  "ptid_time": "082_S_2121_2014-12-11",
  "img_path": "/data/qiuhui/data/adni/images/082_S_2121/2014-12-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 29,397 mm³, 4.7% above the reference mean. With a Z-score of 0.11 (54.3th percentile), this represents normal volume ; hippocampal volume measures 6,607 mm³, 7.1% below the reference mean. With a Z-score of -0.65 (25.6th percentile), this represents normal volume ; whole brain volume measures 1,088,530 mm³, 11.7% above the reference mean. With a Z-score of 1.47 (92.9th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,253 mm³, 11.4% below the reference mean. With a Z-score of -0.70 (24.1th percentile), this represents normal volume ; fusiform gyrus volume measures 20,955 mm³, 23.2% above the reference mean. With a Z-score of 2.11 (98.3th percentile), this represents significant enlargement; middle temporal gyrus volume measures 21,289 mm³, 11.1% above the reference mean. With a Z-score of 0.96 (83.1th percentile), this represents normal volume . ",
  "text_data": "Age is 71.8 years. Gender is Female. Education: 14 years. MMSE: 28.0. MoCA: 23.0. Logical Memory: 11.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.26 SUVR (mild elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume is slightly reduced (7.1% below mean, Z-score -0.65), and the entorhinal cortex is also mildly reduced (11.4% below mean, Z-score -0.70), which may indicate early neurodegeneration. However, the MMSE is normal (28), while the MoCA (23) suggests mild cognitive impairment (MCI). The presence of one APOE4 allele and mild amyloid (AV45) elevation supports a higher risk for progression.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting cognitive scores and only mild structural changes)",
  "timestamp": "2025-07-26T10:03:44.225032"
}