{
  "ptid_time": "024_S_4169_2011-08-12",
  "img_path": "/data/qiuhui/data/adni/images/024_S_4169/2011-08-12/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,010 mm³, 5.9% below the reference mean. With a Z-score of -0.15 (44.1th percentile), this represents normal volume ; hippocampal volume measures 7,472 mm³, 2.8% below the reference mean. With a Z-score of -0.31 (37.8th percentile), this represents normal volume ; whole brain volume measures 1,160,330 mm³, 12.7% above the reference mean. With a Z-score of 1.59 (94.4th percentile), this represents moderate enlargement; entorhinal cortex volume measures 3,678 mm³, 5.5% below the reference mean. With a Z-score of -0.43 (33.4th percentile), this represents normal volume ; fusiform gyrus volume measures 20,771 mm³, 14.1% above the reference mean. With a Z-score of 1.58 (94.3th percentile), this represents moderate enlargement; middle temporal gyrus volume measures 22,125 mm³, 7.8% above the reference mean. With a Z-score of 0.70 (75.7th percentile), this represents normal volume . ",
  "text_data": "Age is 62.0 years. Gender is Female. Education: 13 years. Handedness: Right. Race: Black or African American. Medical history: Psychiatric; Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Musculoskeletal; Gastrointestinal; Hematopoietic-Lymphatic; Renal-Genitourinary; Smoking; Major Surgical Procedures. MMSE: 28.0. MoCA: 25.0. Logical Memory: 4.0. Laboratory findings: MCH: 26.00 (significant reduced); Creatine Kinase: 341.00 (profound elevated); LDH: 256.00 (profound elevated); Triglycerides (GPO): 313.00 (profound elevated); GGT: 47.00 (profound elevated). APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.11 SUVR (normal ); Amyloid beta: 1558.00 pg/mL (mild elevated); Total tau: 228.80 pg/mL (normal ); Phosphorylated tau: 21.86 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges, with only mild deviations (e.g., slightly reduced hippocampal and entorhinal cortex volumes). Cognitive scores (MMSE 28, MoCA 25) are normal, and biomarkers show only mild Aβ elevation without tau pathology.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** Medium (due to mild Aβ elevation, but no significant structural or cognitive impairment)",
  "timestamp": "2025-07-26T03:18:53.155830"
}