{
  "ptid_time": "116_S_1243_2010-02-25",
  "img_path": "/data/qiuhui/data/adni/images/116_S_1243/2010-02-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 34,523 mm³, 26.6% below the reference mean. With a Z-score of -0.77 (22.0th percentile), this represents normal volume ; hippocampal volume measures 4,038 mm³, 42.1% below the reference mean. With a Z-score of -3.63 (0.0th percentile), this represents profound atrophy; whole brain volume measures 935,870 mm³, 9.1% below the reference mean. With a Z-score of -1.19 (11.7th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,699 mm³, 57.2% below the reference mean. With a Z-score of -3.74 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 18,007 mm³, 0.3% below the reference mean. With a Z-score of -0.03 (48.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,881 mm³, 3.5% above the reference mean. With a Z-score of 0.32 (62.4th percentile), this represents normal volume . ",
  "text_data": "Age is 80.3 years. Gender is Male. Education: 16 years. MMSE: 21.0. Logical Memory: 1.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows profound atrophy in the hippocampus and entorhinal cortex (both at 0.0th percentile), which are key regions affected in Alzheimer's disease. The MMSE score of 21 indicates cognitive impairment, consistent with dementia. The presence of one APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T12:02:03.631677"
}