{
  "ptid_time": "052_S_1346_2008-10-28",
  "img_path": "/data/qiuhui/data/adni/images/052_S_1346/2008-10-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 87,567 mm³, 127.3% above the reference mean. With a Z-score of 3.05 (99.9th percentile), this represents profound enlargement; hippocampal volume measures 4,590 mm³, 39.3% below the reference mean. With a Z-score of -3.83 (0.0th percentile), this represents profound atrophy; whole brain volume measures 1,135,580 mm³, 5.2% above the reference mean. With a Z-score of 0.68 (75.0th percentile), this represents normal volume ; entorhinal cortex volume measures 2,811 mm³, 31.4% below the reference mean. With a Z-score of -2.13 (1.6th percentile), this represents significant atrophy; fusiform gyrus volume measures 18,403 mm³, 2.3% below the reference mean. With a Z-score of -0.20 (42.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,448 mm³, 5.2% above the reference mean. With a Z-score of 0.47 (68.0th percentile), this represents normal volume . ",
  "text_data": "Age is 74.1 years. Gender is Male. Education: 12 years. MMSE: 29.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The data shows profound hippocampal and entorhinal cortex atrophy, which are hallmark features of Alzheimer's disease (AD), along with significant ventricular enlargement (a marker of neurodegeneration). However, the MMSE score of 29 is within the normal range, suggesting preserved cognitive function despite structural changes.  \nDiagnosis: **MCI (likely prodromal AD)**  \nConfidence: **Medium** (due to the discrepancy between structural atrophy and intact cognition, though the atrophy pattern strongly suggests early AD pathology)",
  "timestamp": "2025-07-26T07:46:21.436332"
}