{
  "ptid_time": "036_S_0759_2006-08-22",
  "img_path": "/data/qiuhui/data/adni/images/036_S_0759/2006-08-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 43,977 mm³, 19.0% above the reference mean. With a Z-score of 0.51 (69.6th percentile), this represents normal volume ; hippocampal volume measures 4,674 mm³, 28.0% below the reference mean. With a Z-score of -2.25 (1.2th percentile), this represents significant atrophy; whole brain volume measures 849,463 mm³, 8.5% below the reference mean. With a Z-score of -1.02 (15.4th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,698 mm³, 51.0% below the reference mean. With a Z-score of -2.75 (0.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 13,264 mm³, 17.7% below the reference mean. With a Z-score of -1.33 (9.2th percentile), this represents mild atrophy; middle temporal gyrus volume measures 16,530 mm³, 8.3% below the reference mean. With a Z-score of -0.74 (23.0th percentile), this represents normal volume . ",
  "text_data": "Age is 81.8 years. Gender is Female. Education: 12 years. Handedness: Right. Race: White. Medical history: Hepatic; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Malignancy; Major Surgical Procedures. MMSE: 22.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease, along with mild whole-brain and fusiform gyrus atrophy. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T06:04:39.939029"
}