{
  "ptid_time": "023_S_0126_2009-03-03",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0126/2009-03-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 46,302 mm³, 25.3% above the reference mean. With a Z-score of 0.68 (75.2th percentile), this represents normal volume ; hippocampal volume measures 4,003 mm³, 38.4% below the reference mean. With a Z-score of -3.07 (0.1th percentile), this represents profound atrophy; whole brain volume measures 844,616 mm³, 9.0% below the reference mean. With a Z-score of -1.08 (14.0th percentile), this represents mild atrophy; entorhinal cortex volume measures 1,840 mm³, 46.9% below the reference mean. With a Z-score of -2.53 (0.6th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,265 mm³, 30.1% below the reference mean. With a Z-score of -2.26 (1.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,356 mm³, 25.9% below the reference mean. With a Z-score of -2.31 (1.1th percentile), this represents significant atrophy. ",
  "text_data": "Age is 80.5 years. Gender is Female. Education: 14 years. MMSE: 22.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows profound atrophy in the hippocampus, significant atrophy in the entorhinal cortex, fusiform gyrus, and middle temporal gyrus—all key regions affected in Alzheimer’s disease. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele further supports Alzheimer’s pathology.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T02:36:57.059157"
}