{
  "ptid_time": "127_S_1419_2010-08-17",
  "img_path": "/data/qiuhui/data/adni/images/127_S_1419/2010-08-17/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 52,598 mm³, 11.9% above the reference mean. With a Z-score of 0.34 (63.5th percentile), this represents normal volume ; hippocampal volume measures 6,830 mm³, 2.0% below the reference mean. With a Z-score of -0.17 (43.2th percentile), this represents normal volume ; whole brain volume measures 1,141,370 mm³, 10.9% above the reference mean. With a Z-score of 1.43 (92.3th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,718 mm³, 6.3% below the reference mean. With a Z-score of -0.41 (33.9th percentile), this represents normal volume ; fusiform gyrus volume measures 20,764 mm³, 14.9% above the reference mean. With a Z-score of 1.29 (90.2th percentile), this represents mild enlargement; middle temporal gyrus volume measures 23,877 mm³, 18.4% above the reference mean. With a Z-score of 1.65 (95.0th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 80.9 years. Gender is Male. Education: 17 years. Handedness: Right. Race: White. MMSE: 29.0. MoCA: 24.0. Logical Memory: 5.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.40 SUVR (significant elevated); Amyloid beta: 368.30 pg/mL (moderate reduced); Total tau: 292.40 pg/mL (normal ); Phosphorylated tau: 26.82 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges or mildly/moderately enlarged, with no significant atrophy in key regions like the hippocampus or entorhinal cortex. Cognitive scores (MMSE 29, MoCA 24) are borderline for MCI but not dementia, and biomarker data (moderately reduced Aβ, elevated AV45) suggest amyloid pathology but no significant tauopathy.  \n**Diagnosis:** **MCI** (mild cognitive impairment)  \n**Confidence:** **Medium** (cognitive scores are borderline, and biomarker evidence supports early amyloid deposition but lacks strong neurodegenerative markers).",
  "timestamp": "2025-07-26T13:08:53.317504"
}