{
  "ptid_time": "130_S_0505_2006-10-18",
  "img_path": "/data/qiuhui/data/adni/images/130_S_0505/2006-10-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 26,205 mm³, 32.0% below the reference mean. With a Z-score of -0.77 (22.2th percentile), this represents normal volume ; hippocampal volume measures 5,388 mm³, 28.7% below the reference mean. With a Z-score of -2.80 (0.3th percentile), this represents significant atrophy; whole brain volume measures 982,353 mm³, 9.0% below the reference mean. With a Z-score of -1.17 (12.2th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,469 mm³, 39.8% below the reference mean. With a Z-score of -2.70 (0.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 15,543 mm³, 17.5% below the reference mean. With a Z-score of -1.49 (6.8th percentile), this represents mild atrophy; middle temporal gyrus volume measures 17,250 mm³, 19.2% below the reference mean. With a Z-score of -1.72 (4.2th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 79.7 years. Gender is Male. Education: 16 years. MMSE: 28.0. Logical Memory: 8.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 1600.00 pg/mL (mild elevated); Total tau: 176.30 pg/mL (normal ); Phosphorylated tau: 15.57 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus and entorhinal cortex (both at the 0.3th percentile), which are key regions affected in Alzheimer's disease (AD). The MMSE score of 28 is within the normal range, but the presence of mild Aβ elevation suggests early AD pathology. The lack of APOE4 and normal tau levels may indicate a slower progression.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology)  \n**Confidence:** **Medium** (due to normal MMSE but significant atrophy and Aβ elevation)",
  "timestamp": "2025-07-26T14:29:50.106492"
}