{
  "ptid_time": "027_S_0120_2006-02-06",
  "img_path": "/data/qiuhui/data/adni/images/027_S_0120/2006-02-06/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 15,289 mm³, 60.3% below the reference mean. With a Z-score of -1.44 (7.4th percentile), this represents mild atrophy; hippocampal volume measures 7,859 mm³, 4.0% above the reference mean. With a Z-score of 0.39 (65.1th percentile), this represents normal volume ; whole brain volume measures 1,121,590 mm³, 3.9% above the reference mean. With a Z-score of 0.51 (69.4th percentile), this represents normal volume ; entorhinal cortex volume measures 3,289 mm³, 19.8% below the reference mean. With a Z-score of -1.34 (9.0th percentile), this represents mild atrophy; fusiform gyrus volume measures 19,640 mm³, 4.3% above the reference mean. With a Z-score of 0.36 (64.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,655 mm³, 1.5% above the reference mean. With a Z-score of 0.13 (55.3th percentile), this represents normal volume . ",
  "text_data": "Age is 72.0 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Dermatologic-Connective Tissue; Musculoskeletal; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking; Malignancy; Major Surgical Procedures. MMSE: 30.0. Logical Memory: 12.0. APOEε4 alleles: 1.0. Biomarker levels: Amyloid beta: 1226.00 pg/mL (normal ); Total tau: 167.30 pg/mL (normal ); Phosphorylated tau: 14.38 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows mild atrophy in the ventricular volume and entorhinal cortex, but hippocampal, whole brain, fusiform gyrus, and middle temporal gyrus volumes are normal. Clinically, the patient has a normal MMSE (30/30), normal CSF biomarkers (Aβ, T-tau, P-tau), and no significant cognitive complaints.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **High**  \n\n(While mild atrophy in the entorhinal cortex can be an early sign of neurodegeneration, the absence of cognitive impairment, normal biomarkers, and preserved hippocampal volume strongly suggest normal aging rather than MCI or dementia.)",
  "timestamp": "2025-07-26T03:29:33.880625"
}