{
  "ptid_time": "011_S_0183_2006-10-04",
  "img_path": "/data/qiuhui/data/adni/images/011_S_0183/2006-10-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 83,026 mm³, 195.8% above the reference mean. With a Z-score of 4.48 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,811 mm³, 32.4% below the reference mean. With a Z-score of -2.97 (0.1th percentile), this represents significant atrophy; whole brain volume measures 916,691 mm³, 5.9% below the reference mean. With a Z-score of -0.75 (22.7th percentile), this represents normal volume ; entorhinal cortex volume measures 2,740 mm³, 25.4% below the reference mean. With a Z-score of -1.56 (5.9th percentile), this represents moderate atrophy; fusiform gyrus volume measures 12,666 mm³, 25.6% below the reference mean. With a Z-score of -2.33 (1.0th percentile), this represents significant atrophy; middle temporal gyrus volume measures 16,586 mm³, 13.5% below the reference mean. With a Z-score of -1.17 (12.1th percentile), this represents mild atrophy. ",
  "text_data": "Age is 72.9 years. Gender is Female. Education: 14 years. Handedness: Unknown. Race: Unknown. MMSE: 23.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 4.48) and significant hippocampal atrophy (Z-score -2.97), both strongly associated with Alzheimer's pathology. The MMSE score of 23 indicates mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T22:43:46.528002"
}