{
  "ptid_time": "094_S_4089_2013-09-25",
  "img_path": "/data/qiuhui/data/adni/images/094_S_4089/2013-09-25/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 49,515 mm³, 28.6% above the reference mean. With a Z-score of 0.68 (75.3th percentile), this represents normal volume ; hippocampal volume measures 5,366 mm³, 29.0% below the reference mean. With a Z-score of -2.83 (0.2th percentile), this represents significant atrophy; whole brain volume measures 978,467 mm³, 9.4% below the reference mean. With a Z-score of -1.21 (11.2th percentile), this represents mild atrophy. ",
  "text_data": "Age is 75.7 years. Gender is Male. Education: 18 years. MMSE: 18.0. MoCA: 12.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.51 SUVR (profound elevated); Amyloid beta: 633.50 pg/mL (mild reduced); Total tau: 429.20 pg/mL (significant elevated); Phosphorylated tau: 43.16 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant hippocampal atrophy (Z-score -2.83) and mild whole-brain atrophy, along with profoundly elevated amyloid (AV45) and significant tau pathology (elevated T-tau and P-tau). Cognitive scores (MMSE 18, MoCA 12) are severely impaired, consistent with dementia. The combination of structural atrophy, biomarker evidence of Alzheimer’s pathology, and cognitive decline strongly supports a dementia diagnosis.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T10:28:44.511311"
}