{
  "ptid_time": "114_S_0458_2006-05-09",
  "img_path": "/data/qiuhui/data/adni/images/114_S_0458/2006-05-09/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 31,539 mm³, 14.7% below the reference mean. With a Z-score of -0.40 (34.6th percentile), this represents normal volume ; hippocampal volume measures 5,499 mm³, 15.3% below the reference mean. With a Z-score of -1.23 (11.0th percentile), this represents mild atrophy; whole brain volume measures 855,499 mm³, 7.8% below the reference mean. With a Z-score of -0.94 (17.4th percentile), this represents normal volume ; entorhinal cortex volume measures 2,954 mm³, 14.7% below the reference mean. With a Z-score of -0.79 (21.4th percentile), this represents normal volume ; fusiform gyrus volume measures 14,217 mm³, 11.7% below the reference mean. With a Z-score of -0.88 (18.9th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,955 mm³, 0.4% below the reference mean. With a Z-score of -0.04 (48.5th percentile), this represents normal volume . ",
  "text_data": "Age is 82.9 years. Gender is Female. Education: 11 years. Handedness: Right. Race: Black or African American. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Smoking; Major Surgical Procedures. MMSE: 24.0. Logical Memory: 4.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume shows mild atrophy (Z-score -1.23, 11th percentile), which is a key biomarker for Alzheimer's pathology. The MMSE score of 24 suggests mild cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk. Other brain regions show normal or near-normal volumes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Hippocampal atrophy and MMSE support MCI, but clinical correlation and progression monitoring would strengthen confidence.)",
  "timestamp": "2025-07-26T11:41:59.582421"
}