{
  "ptid_time": "032_S_6600_2019-11-21",
  "img_path": "/data/qiuhui/data/adni/images/032_S_6600/2019-11-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 33,757 mm³, 20.3% above the reference mean. With a Z-score of 0.46 (67.9th percentile), this represents normal volume ; hippocampal volume measures 5,346 mm³, 24.9% below the reference mean. With a Z-score of -2.28 (1.1th percentile), this represents significant atrophy; whole brain volume measures 957,370 mm³, 1.8% below the reference mean. With a Z-score of -0.22 (41.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,373 mm³, 35.4% below the reference mean. With a Z-score of -2.17 (1.5th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,534 mm³, 14.6% below the reference mean. With a Z-score of -1.33 (9.2th percentile), this represents mild atrophy; middle temporal gyrus volume measures 17,975 mm³, 6.2% below the reference mean. With a Z-score of -0.54 (29.4th percentile), this represents normal volume . ",
  "text_data": "Age is 72.2 years. Gender is Female. Education: 14 years. MMSE: 13.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient exhibits significant atrophy in the hippocampus and entorhinal cortex (both with Z-scores < -2.0, < 2nd percentile), which are key regions affected in Alzheimer's disease (AD). The MMSE score of 13 indicates severe cognitive impairment, consistent with dementia. The presence of one APOE4 allele further supports AD risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T05:09:20.177044"
}