{
  "ptid_time": "051_S_1331_2008-12-03",
  "img_path": "/data/qiuhui/data/adni/images/051_S_1331/2008-12-03/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 35,602 mm³, 26.8% above the reference mean. With a Z-score of 0.61 (73.1th percentile), this represents normal volume ; hippocampal volume measures 6,059 mm³, 14.8% below the reference mean. With a Z-score of -1.36 (8.7th percentile), this represents mild atrophy; whole brain volume measures 830,511 mm³, 14.8% below the reference mean. With a Z-score of -1.86 (3.1th percentile), this represents moderate atrophy; entorhinal cortex volume measures 3,590 mm³, 2.3% below the reference mean. With a Z-score of -0.14 (44.5th percentile), this represents normal volume ; fusiform gyrus volume measures 10,999 mm³, 35.3% below the reference mean. With a Z-score of -3.22 (0.1th percentile), this represents profound atrophy; middle temporal gyrus volume measures 11,188 mm³, 41.6% below the reference mean. With a Z-score of -3.61 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 78.0 years. Gender is Female. Education: 11 years. MMSE: 28.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the hippocampus, whole brain, fusiform gyrus, and middle temporal gyrus, which are regions commonly affected in Alzheimer's disease. However, the MMSE score of 28 is within the normal range, and the absence of APOE4 reduces genetic risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting biomarkers—structural atrophy suggests neurodegeneration, but preserved cognition complicates the diagnosis)",
  "timestamp": "2025-07-26T07:36:36.073210"
}