{
  "ptid_time": "099_S_0551_2008-05-23",
  "img_path": "/data/qiuhui/data/adni/images/099_S_0551/2008-05-23/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 21,132 mm³, 29.6% below the reference mean. With a Z-score of -0.70 (24.1th percentile), this represents normal volume ; hippocampal volume measures 6,920 mm³, 13.8% below the reference mean. With a Z-score of -1.38 (8.4th percentile), this represents mild atrophy; whole brain volume measures 1,091,160 mm³, 3.8% below the reference mean. With a Z-score of -0.54 (29.4th percentile), this represents normal volume ; entorhinal cortex volume measures 3,137 mm³, 26.4% below the reference mean. With a Z-score of -1.83 (3.4th percentile), this represents moderate atrophy; fusiform gyrus volume measures 15,519 mm³, 22.0% below the reference mean. With a Z-score of -1.83 (3.3th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 18,339 mm³, 18.2% below the reference mean. With a Z-score of -1.50 (6.7th percentile), this represents mild atrophy. ",
  "text_data": "Age is 66.2 years. Gender is Male. Education: 16 years. MMSE: 29.0. Logical Memory: 8.0. Laboratory findings: Serum Glucose: 130.00 (significant elevated); Creatine Kinase: 244.00 (profound elevated). APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows mild to moderate atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), but the MMSE score is normal (29/30), and there is no APOE4 risk allele. The cognitive performance is preserved despite structural changes.  \n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural atrophy suggests neurodegeneration, but high MMSE and lack of APOE4 make dementia less likely. MCI is the most fitting diagnosis, though progression risk is unclear.)",
  "timestamp": "2025-07-26T10:58:46.892974"
}