{
  "ptid_time": "133_S_0727_2008-09-24",
  "img_path": "/data/qiuhui/data/adni/images/133_S_0727/2008-09-24/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 70,437 mm³, 151.0% above the reference mean. With a Z-score of 3.46 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 5,255 mm³, 26.1% below the reference mean. With a Z-score of -2.40 (0.8th percentile), this represents significant atrophy; whole brain volume measures 985,950 mm³, 1.2% above the reference mean. With a Z-score of 0.15 (55.8th percentile), this represents normal volume ; entorhinal cortex volume measures 1,805 mm³, 50.9% below the reference mean. With a Z-score of -3.12 (0.1th percentile), this represents profound atrophy; fusiform gyrus volume measures 13,132 mm³, 22.8% below the reference mean. With a Z-score of -2.08 (1.9th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,689 mm³, 28.6% below the reference mean. With a Z-score of -2.48 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 71.2 years. Gender is Female. Education: 12 years. MMSE: 19.0. Logical Memory: 7.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement and significant atrophy in the hippocampus, entorhinal cortex, fusiform gyrus, and middle temporal gyrus—all key regions affected in Alzheimer's disease. The MMSE score of 19 indicates moderate cognitive impairment, and the presence of two APOE4 alleles further increases Alzheimer's risk.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T15:25:09.941545"
}