{
  "ptid_time": "033_S_1281_2007-09-18",
  "img_path": "/data/qiuhui/data/adni/images/033_S_1281/2007-09-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 20,244 mm³, 27.9% below the reference mean. With a Z-score of -0.64 (26.2th percentile), this represents normal volume ; hippocampal volume measures 4,731 mm³, 33.5% below the reference mean. With a Z-score of -3.07 (0.1th percentile), this represents profound atrophy; whole brain volume measures 898,576 mm³, 7.8% below the reference mean. With a Z-score of -0.98 (16.3th percentile), this represents normal volume ; entorhinal cortex volume measures 2,991 mm³, 18.6% below the reference mean. With a Z-score of -1.14 (12.7th percentile), this represents mild atrophy; fusiform gyrus volume measures 15,926 mm³, 6.4% below the reference mean. With a Z-score of -0.58 (28.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,221 mm³, 15.4% below the reference mean. With a Z-score of -1.34 (9.1th percentile), this represents mild atrophy. ",
  "text_data": "Age is 78.1 years. Gender is Female. Education: 16 years. MMSE: 25.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The hippocampal volume shows profound atrophy (Z-score -3.07, 0.1th percentile), which is strongly associated with Alzheimer's disease. Mild atrophy is also present in the entorhinal cortex and middle temporal gyrus, regions commonly affected in early AD. The MMSE score of 25 is borderline but aligns with early cognitive decline. The presence of two APOE4 alleles further increases AD risk.  \n\nDiagnosis: Dementia (likely Alzheimer’s disease)  \nConfidence: High",
  "timestamp": "2025-07-26T05:31:55.301781"
}