{
  "ptid_time": "023_S_0916_2006-09-22",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0916/2006-09-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 42,972 mm³, 11.6% above the reference mean. With a Z-score of 0.28 (60.9th percentile), this represents normal volume ; hippocampal volume measures 6,321 mm³, 16.4% below the reference mean. With a Z-score of -1.60 (5.5th percentile), this represents moderate atrophy; whole brain volume measures 940,085 mm³, 12.9% below the reference mean. With a Z-score of -1.68 (4.7th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,377 mm³, 42.0% below the reference mean. With a Z-score of -2.85 (0.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,884 mm³, 21.0% below the reference mean. With a Z-score of -1.79 (3.7th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 18,248 mm³, 14.5% below the reference mean. With a Z-score of -1.30 (9.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 79.7 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Gastrointestinal; Renal-Genitourinary; Smoking; Major Surgical Procedures. MMSE: 21.0. Logical Memory: 2.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in the entorhinal cortex (Z-score -2.85, 0.2th percentile) and moderate atrophy in the hippocampus (Z-score -1.60, 5.5th percentile), fusiform gyrus (Z-score -1.79, 3.7th percentile), and whole brain (Z-score -1.68, 4.7th percentile), which are hallmark features of Alzheimer's disease. The MMSE score of 21 (moderate cognitive impairment) and APOE4 homozygosity further support a neurodegenerative process.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T02:48:59.536778"
}