{
  "ptid_time": "153_S_4621_2012-03-28",
  "img_path": "/data/qiuhui/data/adni/images/153_S_4621/2012-03-28/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 67,926 mm³, 126.2% above the reference mean. With a Z-score of 3.00 (99.9th percentile), this represents significant enlargement; hippocampal volume measures 7,729 mm³, 3.7% below the reference mean. With a Z-score of -0.37 (35.5th percentile), this represents normal volume ; whole brain volume measures 1,125,070 mm³, 0.8% below the reference mean. With a Z-score of -0.12 (45.3th percentile), this represents normal volume ; entorhinal cortex volume measures 3,790 mm³, 11.1% below the reference mean. With a Z-score of -0.77 (22.1th percentile), this represents normal volume ; fusiform gyrus volume measures 20,843 mm³, 4.7% above the reference mean. With a Z-score of 0.39 (65.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 23,502 mm³, 4.9% above the reference mean. With a Z-score of 0.40 (65.6th percentile), this represents normal volume . ",
  "text_data": "Age is 69.9 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Cardiovascular; Major Surgical Procedures. MMSE: 28.0. MoCA: 25.0. Logical Memory: 11.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.17 SUVR (normal ); Amyloid beta: 853.30 pg/mL (normal ); Total tau: 169.30 pg/mL (normal ); Phosphorylated tau: 14.55 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (Z-score 3.00), which is a marker of brain atrophy, but hippocampal and whole brain volumes are within normal ranges. Cognitive scores (MMSE 28, MoCA 25) are borderline for MCI but not dementia, and biomarkers (Aβ, tau, AV45) are normal, suggesting no strong evidence of Alzheimer’s pathology.  \n\n**Diagnosis:** **MCI (Mild Cognitive Impairment)**  \n**Confidence:** **Medium** (due to ventricular enlargement and borderline cognitive scores, but normal biomarkers and no significant atrophy in key AD regions)",
  "timestamp": "2025-07-26T17:14:53.969482"
}