{
  "ptid_time": "013_S_5071_2013-08-27",
  "img_path": "/data/qiuhui/data/adni/images/013_S_5071/2013-08-27/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,679 mm³, 16.0% above the reference mean. With a Z-score of 0.38 (64.9th percentile), this represents normal volume ; hippocampal volume measures 6,537 mm³, 13.5% below the reference mean. With a Z-score of -1.32 (9.4th percentile), this represents mild atrophy; whole brain volume measures 1,088,250 mm³, 0.8% above the reference mean. With a Z-score of 0.11 (54.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,972 mm³, 27.5% below the reference mean. With a Z-score of -1.87 (3.1th percentile), this represents moderate atrophy; fusiform gyrus volume measures 16,271 mm³, 13.6% below the reference mean. With a Z-score of -1.16 (12.3th percentile), this represents mild atrophy; middle temporal gyrus volume measures 17,604 mm³, 17.5% below the reference mean. With a Z-score of -1.57 (5.8th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 76.5 years. Gender is Male. Education: 14 years. MMSE: 21.0. APOEε4 alleles: 2.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), with the entorhinal cortex being particularly affected (Z-score -1.87, 3.1st percentile). The MMSE score of 21 indicates cognitive impairment, and the presence of two APOE4 alleles increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High** (due to clear structural atrophy in AD-vulnerable regions, low MMSE, and APOE4 homozygosity)",
  "timestamp": "2025-07-25T23:36:49.635674"
}