{
  "ptid_time": "023_S_1126_2006-12-05",
  "img_path": "/data/qiuhui/data/adni/images/023_S_1126/2006-12-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 55,817 mm³, 18.7% above the reference mean. With a Z-score of 0.54 (70.7th percentile), this represents normal volume ; hippocampal volume measures 4,600 mm³, 34.0% below the reference mean. With a Z-score of -2.94 (0.2th percentile), this represents significant atrophy; whole brain volume measures 1,016,960 mm³, 1.2% below the reference mean. With a Z-score of -0.16 (43.8th percentile), this represents normal volume ; entorhinal cortex volume measures 1,629 mm³, 59.0% below the reference mean. With a Z-score of -3.86 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 18,083 mm³, 0.1% above the reference mean. With a Z-score of 0.01 (50.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,630 mm³, 7.6% below the reference mean. With a Z-score of -0.69 (24.7th percentile), this represents normal volume . ",
  "text_data": "Age is 80.4 years. Gender is Male. Education: 18 years. Handedness: Right. Race: White. Medical history: Cardiovascular. MMSE: 26.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 566.30 pg/mL (mild reduced); Total tau: 237.50 pg/mL (normal ); Phosphorylated tau: 22.82 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant atrophy in the hippocampus (Z-score -2.94) and profound atrophy in the entorhinal cortex (Z-score -3.86), both key regions affected in Alzheimer's disease. Despite mild Aβ reduction, normal tau levels and an MMSE score of 26 suggest cognitive impairment is present but not severe.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural atrophy strongly suggests neurodegeneration, but clinical symptoms are not yet severe enough for a dementia diagnosis.)",
  "timestamp": "2025-07-26T02:54:14.557372"
}