{
  "ptid_time": "009_S_4324_2019-07-11",
  "img_path": "/data/qiuhui/data/adni/images/009_S_4324/2019-07-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 94,050 mm³, 235.1% above the reference mean. With a Z-score of 5.38 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,448 mm³, 37.5% below the reference mean. With a Z-score of -3.44 (0.0th percentile), this represents profound atrophy; whole brain volume measures 748,935 mm³, 23.2% below the reference mean. With a Z-score of -2.92 (0.2th percentile), this represents significant atrophy; entorhinal cortex volume measures 1,684 mm³, 54.2% below the reference mean. With a Z-score of -3.32 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 11,521 mm³, 32.3% below the reference mean. With a Z-score of -2.94 (0.2th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,821 mm³, 27.9% below the reference mean. With a Z-score of -2.42 (0.8th percentile), this represents significant atrophy. ",
  "text_data": "Age is 70.3 years. Gender is Female. Education: 14 years. MMSE: 16.0. MoCA: 11.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex) and significant whole-brain atrophy, alongside severe ventricular enlargement. The cognitive scores (MMSE 16, MoCA 11) are well below normal, indicating substantial impairment. The presence of an APOE4 allele further supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High**",
  "timestamp": "2025-07-25T22:18:49.538310"
}