{
  "ptid_time": "033_S_1283_2007-08-20",
  "img_path": "/data/qiuhui/data/adni/images/033_S_1283/2007-08-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 144,790 mm³, 382.2% above the reference mean. With a Z-score of 9.08 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 6,316 mm³, 21.3% below the reference mean. With a Z-score of -2.13 (1.7th percentile), this represents significant atrophy; whole brain volume measures 1,014,950 mm³, 10.5% below the reference mean. With a Z-score of -1.49 (6.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 3,730 mm³, 12.5% below the reference mean. With a Z-score of -0.87 (19.3th percentile), this represents normal volume ; fusiform gyrus volume measures 17,173 mm³, 13.7% below the reference mean. With a Z-score of -1.14 (12.7th percentile), this represents mild atrophy; middle temporal gyrus volume measures 15,676 mm³, 30.1% below the reference mean. With a Z-score of -2.48 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 60.4 years. Gender is Male. Education: 16 years. MMSE: 22.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 9.08) and significant hippocampal atrophy (Z-score -2.13), both strongly associated with Alzheimer's disease. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \n\n**Diagnosis:** **Dementia** (likely Alzheimer’s disease)  \n**Confidence:** **High** (due to severe structural atrophy and cognitive decline)",
  "timestamp": "2025-07-26T05:32:27.434494"
}