{
  "ptid_time": "098_S_0667_2006-06-24",
  "img_path": "/data/qiuhui/data/adni/images/098_S_0667/2006-06-24/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 56,507 mm³, 88.2% above the reference mean. With a Z-score of 2.10 (98.2th percentile), this represents significant enlargement; hippocampal volume measures 8,811 mm³, 9.8% above the reference mean. With a Z-score of 0.98 (83.5th percentile), this represents normal volume ; whole brain volume measures 1,199,150 mm³, 5.7% above the reference mean. With a Z-score of 0.81 (79.0th percentile), this represents normal volume ; entorhinal cortex volume measures 4,294 mm³, 0.7% above the reference mean. With a Z-score of 0.05 (52.0th percentile), this represents normal volume ; fusiform gyrus volume measures 17,130 mm³, 14.0% below the reference mean. With a Z-score of -1.16 (12.3th percentile), this represents mild atrophy; middle temporal gyrus volume measures 18,266 mm³, 18.5% below the reference mean. With a Z-score of -1.52 (6.4th percentile), this represents moderate atrophy. ",
  "text_data": "Age is 69.0 years. Gender is Male. Education: 20 years. Handedness: Right. Race: White. Medical history: Head, Eyes, Ears, Nose and Throat; Renal-Genitourinary; Allergies or Drug Sensitivities; Smoking; Malignancy; Major Surgical Procedures. MMSE: 28.0. Logical Memory: 4.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows significant ventricular enlargement (indicative of brain atrophy) and moderate atrophy in the middle temporal gyrus, which is often associated with Alzheimer's pathology. However, hippocampal volume is normal, and MMSE is intact (28/30), suggesting preserved cognitive function. The presence of one APOE4 allele increases Alzheimer's risk but does not confirm dementia.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (structural changes without significant cognitive decline)  \n**Confidence:** **Medium** (due to conflicting markers—some atrophy but normal cognition and hippocampal volume)",
  "timestamp": "2025-07-26T10:40:59.342875"
}