{
  "ptid_time": "053_S_0621_2008-06-18",
  "img_path": "/data/qiuhui/data/adni/images/053_S_0621/2008-06-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 30,536 mm³, 36.7% above the reference mean. With a Z-score of 0.92 (82.1th percentile), this represents normal volume ; hippocampal volume measures 7,444 mm³, 3.1% below the reference mean. With a Z-score of -0.35 (36.3th percentile), this represents normal volume ; whole brain volume measures 1,272,450 mm³, 23.6% above the reference mean. With a Z-score of 2.94 (99.8th percentile), this represents significant enlargement; entorhinal cortex volume measures 3,287 mm³, 15.6% below the reference mean. With a Z-score of -1.21 (11.4th percentile), this represents mild atrophy; fusiform gyrus volume measures 17,996 mm³, 1.2% below the reference mean. With a Z-score of -0.13 (44.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,223 mm³, 8.3% above the reference mean. With a Z-score of 0.74 (77.0th percentile), this represents normal volume . ",
  "text_data": "Age is 64.3 years. Gender is Female. Education: 16 years. MMSE: 27.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The entorhinal cortex shows mild atrophy (Z-score -1.21, 11.4th percentile), which is an early marker of Alzheimer's pathology, but hippocampal volume is normal (Z-score -0.35). MMSE score of 27 is within normal limits, and other brain regions are largely normal or enlarged. APOE4 carrier status increases risk but does not confirm disease.  \nDiagnosis: CN (Cognitively Normal)  \nConfidence: Medium (Mild entorhinal atrophy is concerning, but cognitive scores and other volumes do not yet suggest impairment.)",
  "timestamp": "2025-07-26T07:55:26.923076"
}