{
  "ptid_time": "072_S_4694_2012-06-15",
  "img_path": "/data/qiuhui/data/adni/images/072_S_4694/2012-06-15/t1.nii.gz",
  "img_finding": "Image findings: hippocampal volume measures 8,659 mm³, 12.7% above the reference mean. With a Z-score of 1.42 (92.3th percentile), this represents mild enlargement. ",
  "text_data": "Age is 64.8 years. Gender is Female. Education: 14 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Endocrine-Metabolic; Major Surgical Procedures. MMSE: 29.0. MoCA: 22.0. Logical Memory: 9.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.01 SUVR (normal ); Amyloid beta: 1437.00 pg/mL (mild elevated); Total tau: 132.40 pg/mL (mild reduced); Phosphorylated tau: 10.72 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume is mildly enlarged (12.7% above mean, Z-score 1.42), which is atypical for Alzheimer's but not necessarily pathological. Cognitive testing shows a discrepancy between MMSE (29, normal) and MoCA (22, borderline impaired), along with mildly elevated Aβ but normal AV45 and reduced tau biomarkers, suggesting possible early cognitive changes but not a clear neurodegenerative pattern.  \n\n**Diagnosis:** **MCI** (due to MoCA score and biomarker inconsistencies, but not meeting dementia criteria)  \n**Confidence:** **Medium** (unusual hippocampal enlargement complicates interpretation, and biomarker profile is mixed)",
  "timestamp": "2025-07-26T09:25:56.403850"
}