{
  "ptid_time": "141_S_2333_2019-12-20",
  "img_path": "/data/qiuhui/data/adni/images/141_S_2333/2019-12-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 42,462 mm³, 10.2% above the reference mean. With a Z-score of 0.25 (59.7th percentile), this represents normal volume ; hippocampal volume measures 5,859 mm³, 22.5% below the reference mean. With a Z-score of -2.19 (1.4th percentile), this represents significant atrophy; whole brain volume measures 1,014,790 mm³, 6.0% below the reference mean. With a Z-score of -0.78 (21.9th percentile), this represents normal volume ; entorhinal cortex volume measures 3,690 mm³, 10.0% below the reference mean. With a Z-score of -0.68 (24.9th percentile), this represents normal volume ; fusiform gyrus volume measures 18,602 mm³, 1.3% below the reference mean. With a Z-score of -0.11 (45.7th percentile), this represents normal volume ; middle temporal gyrus volume measures 16,038 mm³, 24.8% below the reference mean. With a Z-score of -2.23 (1.3th percentile), this represents significant atrophy. ",
  "text_data": "Age is 75.5 years. Gender is Male. Education: 12 years. MMSE: 26.0. MoCA: 20.0. Logical Memory: 8.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.63 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal volume and middle temporal gyrus show significant atrophy (Z-scores ≤ -2.19, ≤1.4th percentile), which are key biomarkers for Alzheimer's disease. The MMSE (26) is borderline, but the MoCA (20) suggests cognitive impairment, and the elevated AV45 (amyloid PET) supports Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T17:01:19.079633"
}