{
  "ptid_time": "051_S_1131_2008-08-01",
  "img_path": "/data/qiuhui/data/adni/images/051_S_1131/2008-08-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 106,308 mm³, 126.1% above the reference mean. With a Z-score of 3.66 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 7,688 mm³, 10.3% above the reference mean. With a Z-score of 0.89 (81.4th percentile), this represents normal volume ; whole brain volume measures 1,098,900 mm³, 6.8% above the reference mean. With a Z-score of 0.89 (81.3th percentile), this represents normal volume ; entorhinal cortex volume measures 3,907 mm³, 1.6% below the reference mean. With a Z-score of -0.10 (45.9th percentile), this represents normal volume ; fusiform gyrus volume measures 20,469 mm³, 13.3% above the reference mean. With a Z-score of 1.15 (87.5th percentile), this represents mild enlargement; middle temporal gyrus volume measures 23,196 mm³, 15.0% above the reference mean. With a Z-score of 1.34 (91.1th percentile), this represents mild enlargement. ",
  "text_data": "Age is 87.9 years. Gender is Male. Education: 7 years. MMSE: 27.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.66), which is strongly associated with neurodegeneration, but hippocampal and whole brain volumes are within normal ranges. The MMSE score of 27 is borderline but still within normal limits for age, and the absence of APOE4 reduces genetic risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (due to conflicting markers—ventricular enlargement suggests pathology, but preserved hippocampal volume and normal MMSE complicate the diagnosis)",
  "timestamp": "2025-07-26T07:34:42.734556"
}