{
  "ptid_time": "099_S_0054_2007-12-20",
  "img_path": "/data/qiuhui/data/adni/images/099_S_0054/2007-12-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 87,429 mm³, 136.5% above the reference mean. With a Z-score of 3.69 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 4,091 mm³, 37.0% below the reference mean. With a Z-score of -2.97 (0.2th percentile), this represents significant atrophy; whole brain volume measures 809,740 mm³, 12.8% below the reference mean. With a Z-score of -1.53 (6.3th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,023 mm³, 41.6% below the reference mean. With a Z-score of -2.24 (1.2th percentile), this represents significant atrophy; fusiform gyrus volume measures 11,684 mm³, 27.5% below the reference mean. With a Z-score of -2.07 (1.9th percentile), this represents significant atrophy; middle temporal gyrus volume measures 13,042 mm³, 27.7% below the reference mean. With a Z-score of -2.46 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 83.0 years. Gender is Female. Education: 20 years. MMSE: 19.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement and significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, fusiform gyrus, middle temporal gyrus), alongside moderate whole-brain atrophy. The MMSE score of 19 (indicating moderate cognitive impairment) in an 83-year-old female further supports neurodegeneration. The absence of APOE4 does not rule out Alzheimer's, as atrophy patterns are highly suggestive.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T10:52:09.925008"
}