{
  "ptid_time": "029_S_0914_2008-01-31",
  "img_path": "/data/qiuhui/data/adni/images/029_S_0914/2008-01-31/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 38,101 mm³, 1.1% below the reference mean. With a Z-score of -0.03 (49.0th percentile), this represents normal volume ; hippocampal volume measures 6,224 mm³, 17.7% below the reference mean. With a Z-score of -1.72 (4.2th percentile), this represents moderate atrophy; whole brain volume measures 1,169,920 mm³, 8.4% above the reference mean. With a Z-score of 1.09 (86.2th percentile), this represents mild enlargement; entorhinal cortex volume measures 2,891 mm³, 29.5% below the reference mean. With a Z-score of -2.00 (2.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 17,894 mm³, 5.0% below the reference mean. With a Z-score of -0.43 (33.5th percentile), this represents normal volume ; middle temporal gyrus volume measures 20,202 mm³, 5.3% below the reference mean. With a Z-score of -0.48 (31.6th percentile), this represents normal volume . ",
  "text_data": "Age is 75.4 years. Gender is Male. Education: 12 years. MMSE: 29.0. Logical Memory: 14.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The hippocampal and entorhinal cortex volumes show significant atrophy (Z-scores of -1.72 and -2.00, respectively), which are key biomarkers for Alzheimer's pathology. However, the MMSE score of 29 is within the normal range, suggesting preserved cognitive function despite structural changes.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (due to structural atrophy with intact cognition)  \n**Confidence:** **Medium** (high confidence in atrophy, but MCI diagnosis is tentative due to normal MMSE; clinical correlation needed for subjective cognitive complaints or other neuropsychological deficits).",
  "timestamp": "2025-07-26T04:20:03.163270"
}