{
  "ptid_time": "012_S_0932_2006-09-20",
  "img_path": "/data/qiuhui/data/adni/images/012_S_0932/2006-09-20/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,979 mm³, 16.8% above the reference mean. With a Z-score of 0.40 (65.6th percentile), this represents normal volume ; hippocampal volume measures 7,161 mm³, 5.3% below the reference mean. With a Z-score of -0.51 (30.4th percentile), this represents normal volume ; whole brain volume measures 1,085,110 mm³, 0.5% above the reference mean. With a Z-score of 0.07 (52.7th percentile), this represents normal volume ; entorhinal cortex volume measures 3,574 mm³, 12.8% below the reference mean. With a Z-score of -0.87 (19.2th percentile), this represents normal volume ; fusiform gyrus volume measures 18,129 mm³, 3.8% below the reference mean. With a Z-score of -0.32 (37.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,327 mm³, 0.1% below the reference mean. With a Z-score of -0.01 (49.8th percentile), this represents normal volume . ",
  "text_data": "Age is 75.3 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. Medical history: Psychiatric; Neurologic; Head, Eyes, Ears, Nose and Throat; Cardiovascular; Respiratory; Endocrine-Metabolic; Gastrointestinal; Renal-Genitourinary; Smoking; Major Surgical Procedures. MMSE: 27.0. Logical Memory: 7.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 579.20 pg/mL (mild reduced); Total tau: 236.10 pg/mL (normal ); Phosphorylated tau: 22.57 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volumes (hippocampal, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) are within normal ranges, though some structures like the entorhinal cortex show mild reductions. The MMSE score of 27 is within the normal range, and biomarkers (Aβ mildly reduced, normal T-tau and P-tau) suggest minimal amyloid pathology without significant neurodegeneration.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **Medium** (due to mildly reduced Aβ but otherwise normal clinical and structural findings)",
  "timestamp": "2025-07-25T23:07:12.785437"
}