{
  "ptid_time": "067_S_0076_2006-07-14",
  "img_path": "/data/qiuhui/data/adni/images/067_S_0076/2006-07-14/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 33,198 mm³, 13.8% below the reference mean. With a Z-score of -0.33 (37.0th percentile), this represents normal volume ; hippocampal volume measures 4,529 mm³, 40.1% below the reference mean. With a Z-score of -3.91 (0.0th percentile), this represents profound atrophy; whole brain volume measures 915,969 mm³, 15.1% below the reference mean. With a Z-score of -1.97 (2.5th percentile), this represents moderate atrophy; entorhinal cortex volume measures 2,076 mm³, 49.4% below the reference mean. With a Z-score of -3.35 (0.0th percentile), this represents profound atrophy; fusiform gyrus volume measures 14,224 mm³, 24.5% below the reference mean. With a Z-score of -2.09 (1.8th percentile), this represents significant atrophy; middle temporal gyrus volume measures 15,242 mm³, 28.6% below the reference mean. With a Z-score of -2.57 (0.5th percentile), this represents significant atrophy. ",
  "text_data": "Age is 78.8 years. Gender is Male. Education: 12 years. MMSE: 25.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound atrophy in the hippocampus and entorhinal cortex, which are key regions affected in Alzheimer's disease (AD). Moderate to significant atrophy is also present in the whole brain, fusiform gyrus, and middle temporal gyrus, while ventricular volume remains normal. The MMSE score of 25 is borderline, but the structural changes strongly suggest neurodegeneration.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T08:24:42.646190"
}