{
  "ptid_time": "007_S_4637_2012-04-05",
  "img_path": "/data/qiuhui/data/adni/images/007_S_4637/2012-04-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 25,048 mm³, 10.8% below the reference mean. With a Z-score of -0.25 (40.3th percentile), this represents normal volume ; hippocampal volume measures 6,918 mm³, 2.8% below the reference mean. With a Z-score of -0.25 (40.0th percentile), this represents normal volume ; whole brain volume measures 993,126 mm³, 1.9% above the reference mean. With a Z-score of 0.24 (59.4th percentile), this represents normal volume ; entorhinal cortex volume measures 3,509 mm³, 4.5% below the reference mean. With a Z-score of -0.27 (39.2th percentile), this represents normal volume ; fusiform gyrus volume measures 16,919 mm³, 0.6% below the reference mean. With a Z-score of -0.05 (48.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,119 mm³, 0.3% below the reference mean. With a Z-score of -0.02 (49.1th percentile), this represents normal volume . ",
  "text_data": "Age is 70.8 years. Gender is Female. Education: 18 years. Handedness: Right. Race: White. Medical history: Neurologic; Head, Eyes, Ears, Nose and Throat; Dermatologic-Connective Tissue; Musculoskeletal; Renal-Genitourinary; Allergies or Drug Sensitivities; Major Surgical Procedures. MMSE: 29.0. MoCA: 29.0. Logical Memory: 16.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.10 SUVR (normal ); Amyloid beta: 351.40 pg/mL (moderate reduced); Total tau: 203.40 pg/mL (normal ); Phosphorylated tau: 19.09 pg/mL (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** All brain volumes (ventricular, hippocampal, whole brain, entorhinal cortex, fusiform gyrus, and middle temporal gyrus) fall within normal ranges based on Z-scores and percentiles. Cognitive screening (MMSE 29, MoCA 29) is intact, and CSF biomarkers show only moderately reduced Aβ with normal tau and AV45. APOE4-negative status further reduces Alzheimer's risk.  \n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-25T22:05:25.516467"
}