{
  "ptid_time": "130_S_4415_2016-01-29",
  "img_path": "/data/qiuhui/data/adni/images/130_S_4415/2016-01-29/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,399 mm³, 48.7% below the reference mean. With a Z-score of -1.12 (13.2th percentile), this represents mild atrophy; hippocampal volume measures 5,507 mm³, 22.6% below the reference mean. With a Z-score of -2.07 (1.9th percentile), this represents significant atrophy; whole brain volume measures 873,409 mm³, 10.4% below the reference mean. With a Z-score of -1.31 (9.5th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,044 mm³, 44.3% below the reference mean. With a Z-score of -2.72 (0.3th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,198 mm³, 16.5% below the reference mean. With a Z-score of -1.51 (6.6th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 14,523 mm³, 24.2% below the reference mean. With a Z-score of -2.10 (1.8th percentile), this represents significant atrophy. ",
  "text_data": "Age is 79.1 years. Gender is Female. Education: 13 years. MMSE: 26.0. MoCA: 20.0. Logical Memory: 0.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.90 SUVR (profound elevated); Amyloid beta: 393.70 pg/mL (moderate reduced); Total tau: 915.80 pg/mL (profound elevated); Phosphorylated tau: 103.70 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The imaging data shows significant atrophy in key Alzheimer's-related regions (hippocampus, entorhinal cortex, middle temporal gyrus), along with elevated biomarkers (Aβ, tau, AV45). The cognitive scores (MMSE 26, MoCA 20) suggest mild impairment, consistent with early-stage Alzheimer's pathology.  \n\n**Diagnosis:** **Dementia (likely Alzheimer’s disease)**  \n**Confidence:** **High**",
  "timestamp": "2025-07-26T14:44:10.464387"
}