{
  "ptid_time": "016_S_6834_2019-11-11",
  "img_path": "/data/qiuhui/data/adni/images/016_S_6834/2019-11-11/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 14,993 mm³, 59.4% below the reference mean. With a Z-score of -1.60 (5.4th percentile), this represents moderate atrophy; hippocampal volume measures 7,343 mm³, 13.1% above the reference mean. With a Z-score of 1.05 (85.2th percentile), this represents mild enlargement; whole brain volume measures 945,680 mm³, 1.9% above the reference mean. With a Z-score of 0.23 (58.9th percentile), this represents normal volume ; entorhinal cortex volume measures 3,375 mm³, 2.5% below the reference mean. With a Z-score of -0.14 (44.6th percentile), this represents normal volume ; fusiform gyrus volume measures 14,772 mm³, 8.3% below the reference mean. With a Z-score of -0.62 (26.6th percentile), this represents normal volume ; middle temporal gyrus volume measures 17,554 mm³, 2.6% below the reference mean. With a Z-score of -0.23 (40.7th percentile), this represents normal volume . ",
  "text_data": "Age is 82.3 years. Gender is Female. Education: 16 years. Handedness: Right. Race: Black or African American. MMSE: 30.0. MoCA: 24.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Flobetaben (FBB): 1.03 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows moderate ventricular atrophy (Z-score -1.60) but otherwise normal or mildly enlarged brain volumes (hippocampus is slightly enlarged). Cognitive scores are mixed (MMSE 30 is normal, MoCA 24 suggests mild impairment). No APOE4 risk allele is present. The absence of significant atrophy in Alzheimer’s-vulnerable regions (e.g., hippocampus, entorhinal cortex) and the high MMSE argue against dementia.  \n**Diagnosis:** **MCI** (due to MoCA 24 and possible early cognitive changes, but structural findings are not strongly supportive of neurodegeneration).  \n**Confidence:** **Medium** (discrepancy between MMSE/MoCA and lack of clear atrophy patterns lowers certainty).",
  "timestamp": "2025-07-26T00:41:23.950880"
}