{
  "ptid_time": "116_S_0487_2006-12-22",
  "img_path": "/data/qiuhui/data/adni/images/116_S_0487/2006-12-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 44,847 mm³, 16.4% above the reference mean. With a Z-score of 0.39 (65.3th percentile), this represents normal volume ; hippocampal volume measures 4,661 mm³, 38.3% below the reference mean. With a Z-score of -3.74 (0.0th percentile), this represents profound atrophy; whole brain volume measures 864,584 mm³, 19.9% below the reference mean. With a Z-score of -2.58 (0.5th percentile), this represents significant atrophy; entorhinal cortex volume measures 2,630 mm³, 35.9% below the reference mean. With a Z-score of -2.43 (0.8th percentile), this represents significant atrophy; fusiform gyrus volume measures 14,761 mm³, 21.6% below the reference mean. With a Z-score of -1.84 (3.3th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 15,521 mm³, 27.3% below the reference mean. With a Z-score of -2.45 (0.7th percentile), this represents significant atrophy. ",
  "text_data": "Age is 76.9 years. Gender is Male. Education: 20 years. MMSE: 22.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The patient shows profound hippocampal atrophy (-3.74 Z-score) and significant atrophy in whole brain, entorhinal cortex, and middle temporal gyrus, consistent with Alzheimer's pathology. The MMSE score of 22 indicates cognitive impairment, and the presence of one APOE4 allele further supports Alzheimer's risk.  \nDiagnosis: Dementia (likely Alzheimer’s disease)  \nConfidence: High",
  "timestamp": "2025-07-26T11:54:52.542777"
}