{
  "ptid_time": "027_S_2245_2017-02-01",
  "img_path": "/data/qiuhui/data/adni/images/027_S_2245/2017-02-01/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 20,688 mm³, 7.4% below the reference mean. With a Z-score of -0.18 (42.7th percentile), this represents normal volume ; hippocampal volume measures 8,011 mm³, 4.3% above the reference mean. With a Z-score of 0.48 (68.3th percentile), this represents normal volume ; whole brain volume measures 1,003,450 mm³, 2.5% below the reference mean. With a Z-score of -0.31 (37.8th percentile), this represents normal volume ; entorhinal cortex volume measures 4,697 mm³, 20.7% above the reference mean. With a Z-score of 1.60 (94.5th percentile), this represents moderate enlargement; fusiform gyrus volume measures 17,679 mm³, 2.9% below the reference mean. With a Z-score of -0.33 (37.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 21,150 mm³, 3.1% above the reference mean. With a Z-score of 0.27 (60.8th percentile), this represents normal volume . ",
  "text_data": "Age is 63.0 years. Gender is Female. Education: 20 years. MMSE: 30.0. MoCA: 28.0. Logical Memory: 14.0. APOEε4 alleles: 2.0. Biomarker levels: Florbetapir (AV45): 1.20 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges, with no significant atrophy in key regions like the hippocampus or middle temporal gyrus. The entorhinal cortex shows moderate enlargement, which is atypical for Alzheimer's but not indicative of neurodegeneration. Cognitive scores (MMSE 30, MoCA 28) are normal, and amyloid PET (AV45) is negative despite APOE4 homozygosity.  \n\n**Diagnosis:** CN (Cognitively Normal)  \n**Confidence:** High",
  "timestamp": "2025-07-26T03:54:59.545010"
}