{
  "ptid_time": "021_S_0141_2010-02-22",
  "img_path": "/data/qiuhui/data/adni/images/021_S_0141/2010-02-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 28,209 mm³, 40.0% below the reference mean. With a Z-score of -1.16 (12.3th percentile), this represents mild atrophy; hippocampal volume measures 6,011 mm³, 13.7% below the reference mean. With a Z-score of -1.19 (11.8th percentile), this represents mild atrophy; whole brain volume measures 1,044,840 mm³, 1.5% above the reference mean. With a Z-score of 0.20 (57.9th percentile), this represents normal volume ; entorhinal cortex volume measures 2,652 mm³, 33.2% below the reference mean. With a Z-score of -2.17 (1.5th percentile), this represents significant atrophy; fusiform gyrus volume measures 17,858 mm³, 1.2% below the reference mean. With a Z-score of -0.10 (46.0th percentile), this represents normal volume ; middle temporal gyrus volume measures 18,199 mm³, 9.8% below the reference mean. With a Z-score of -0.88 (19.0th percentile), this represents normal volume . ",
  "text_data": "Age is 85.1 years. Gender is Male. Education: 12 years. MMSE: 22.0. Logical Memory: 0.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "Reasoning: The data shows significant atrophy in the entorhinal cortex (Z-score -2.17, 1.5th percentile) and mild atrophy in the hippocampus (Z-score -1.19, 11.8th percentile) and ventricles (Z-score -1.16, 12.3th percentile), which are hallmark regions for Alzheimer's pathology. The MMSE score of 22 suggests cognitive impairment, and the presence of one APOE4 allele increases Alzheimer's risk.  \nDiagnosis: Dementia (likely Alzheimer's disease)  \nConfidence: Medium (clinical correlation and biomarker confirmation would strengthen confidence)",
  "timestamp": "2025-07-26T01:20:50.114386"
}