{
  "ptid_time": "072_S_2164_2012-12-04",
  "img_path": "/data/qiuhui/data/adni/images/072_S_2164/2012-12-04/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 16,347 mm³, 41.8% below the reference mean. With a Z-score of -0.96 (16.9th percentile), this represents normal volume ; hippocampal volume measures 7,847 mm³, 10.3% above the reference mean. With a Z-score of 0.94 (82.7th percentile), this represents normal volume ; whole brain volume measures 1,077,340 mm³, 10.5% above the reference mean. With a Z-score of 1.33 (90.8th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,607 mm³, 1.8% below the reference mean. With a Z-score of -0.11 (45.6th percentile), this represents normal volume ; fusiform gyrus volume measures 21,763 mm³, 27.9% above the reference mean. With a Z-score of 2.54 (99.4th percentile), this represents significant enlargement; middle temporal gyrus volume measures 19,768 mm³, 3.1% above the reference mean. With a Z-score of 0.27 (60.7th percentile), this represents normal volume . ",
  "text_data": "Age is 72.9 years. Gender is Female. Education: 16 years. MMSE: 27.0. MoCA: 21.0. Logical Memory: 10.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.13 SUVR (normal ). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements are largely within normal ranges or even enlarged, with no significant atrophy in key regions like the hippocampus or entorhinal cortex. The MMSE score of 27 is within normal limits, but the MoCA score of 21 suggests mild cognitive impairment (MCI). The absence of APOE4 and normal AV45 (amyloid PET) further reduces the likelihood of Alzheimer’s pathology.  \n\n**Diagnosis:** **MCI** (Mild Cognitive Impairment)  \n**Confidence:** **Medium** (due to the discrepancy between MMSE and MoCA, but lack of structural or biomarker evidence for dementia)",
  "timestamp": "2025-07-26T09:14:42.450891"
}