{
  "ptid_time": "011_S_4893_2012-09-10",
  "img_path": "/data/qiuhui/data/adni/images/011_S_4893/2012-09-10/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 15,415 mm³, 31.0% below the reference mean. With a Z-score of -0.78 (21.9th percentile), this represents normal volume ; hippocampal volume measures 6,711 mm³, 12.7% below the reference mean. With a Z-score of -1.42 (7.8th percentile), this represents mild atrophy; whole brain volume measures 968,646 mm³, 5.9% below the reference mean. With a Z-score of -0.73 (23.2th percentile), this represents normal volume ; entorhinal cortex volume measures 2,910 mm³, 25.2% below the reference mean. With a Z-score of -1.96 (2.5th percentile), this represents moderate atrophy; fusiform gyrus volume measures 17,731 mm³, 2.6% below the reference mean. With a Z-score of -0.30 (38.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,365 mm³, 5.6% below the reference mean. With a Z-score of -0.50 (30.9th percentile), this represents normal volume . ",
  "text_data": "Age is 68.1 years. Gender is Female. Education: 12 years. MMSE: 28.0. MoCA: 22.0. Logical Memory: 8.0. APOEε4 alleles: 1.0. Biomarker levels: Florbetapir (AV45): 1.23 SUVR (mild elevated); Amyloid beta: 784.30 pg/mL (normal ); Total tau: 430.60 pg/mL (significant elevated); Phosphorylated tau: 39.87 pg/mL (significant elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The patient shows mild hippocampal atrophy and moderate entorhinal cortex atrophy, both of which are key regions affected in Alzheimer's disease. Elevated T-tau and P-tau with normal Aβ suggest a tauopathy, while the MoCA score of 22 indicates mild cognitive impairment (MCI).  \nDiagnosis: MCI  \nConfidence: Medium  \n\n(Confidence is medium due to the absence of Aβ pathology, which is typical in Alzheimer's, but the tau elevation and structural atrophy strongly suggest neurodegenerative progression.)",
  "timestamp": "2025-07-25T23:00:33.695864"
}