{
  "ptid_time": "018_S_0682_2008-07-22",
  "img_path": "/data/qiuhui/data/adni/images/018_S_0682/2008-07-22/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 39,168 mm³, 1.7% above the reference mean. With a Z-score of 0.04 (51.6th percentile), this represents normal volume ; hippocampal volume measures 5,256 mm³, 30.5% below the reference mean. With a Z-score of -2.97 (0.1th percentile), this represents significant atrophy; whole brain volume measures 851,501 mm³, 21.1% below the reference mean. With a Z-score of -2.74 (0.3th percentile), this represents significant atrophy; entorhinal cortex volume measures 3,176 mm³, 22.5% below the reference mean. With a Z-score of -1.53 (6.3th percentile), this represents moderate atrophy; fusiform gyrus volume measures 14,490 mm³, 23.1% below the reference mean. With a Z-score of -1.97 (2.5th percentile), this represents moderate atrophy; middle temporal gyrus volume measures 13,386 mm³, 37.3% below the reference mean. With a Z-score of -3.35 (0.0th percentile), this represents profound atrophy. ",
  "text_data": "Age is 70.0 years. Gender is Male. Education: 16 years. MMSE: 14.0. APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows significant atrophy in key Alzheimer's-related regions (hippocampus, whole brain, middle temporal gyrus) with profound Z-scores (e.g., -2.97 to -3.35). Combined with a low MMSE score (14/30) and APOE4 positivity, this strongly suggests neurodegenerative disease. The pattern of atrophy and cognitive impairment aligns with Alzheimer's dementia.  \n\n**Diagnosis:** Dementia (likely Alzheimer’s disease)  \n**Confidence:** High",
  "timestamp": "2025-07-26T00:52:19.237267"
}