{
  "ptid_time": "023_S_0855_2006-09-18",
  "img_path": "/data/qiuhui/data/adni/images/023_S_0855/2006-09-18/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 48,795 mm³, 26.7% above the reference mean. With a Z-score of 0.64 (73.9th percentile), this represents normal volume ; whole brain volume measures 1,074,820 mm³, 0.4% below the reference mean. With a Z-score of -0.06 (47.8th percentile), this represents normal volume . ",
  "text_data": "Age is 75.6 years. Gender is Male. Education: 12 years. Handedness: Left. Race: White. Medical history: Cardiovascular; Respiratory; Musculoskeletal; Gastrointestinal; Renal-Genitourinary; Major Surgical Procedures. MMSE: 25.0. Logical Memory: 0.0. APOEε4 alleles: 0.0. Biomarker levels: Amyloid beta: 638.30 pg/mL (mild reduced); Total tau: 495.70 pg/mL (profound elevated); Phosphorylated tau: 58.05 pg/mL (profound elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume and whole brain volume are within normal ranges, suggesting no significant atrophy. However, the MMSE score of 25 is borderline (mild cognitive impairment range), and the CSF biomarkers (Aβ mildly reduced, T-tau and P-tau profoundly elevated) strongly suggest Alzheimer's pathology.  \n\n**Diagnosis:** **MCI (likely due to Alzheimer’s disease)**  \n**Confidence:** **Medium** (due to normal brain volumes but strong biomarker evidence of AD pathology)",
  "timestamp": "2025-07-26T02:46:57.274941"
}