{
  "ptid_time": "012_S_4545_2014-03-31",
  "img_path": "/data/qiuhui/data/adni/images/012_S_4545/2014-03-31/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,779 mm³, 2.0% above the reference mean. With a Z-score of 0.05 (52.0th percentile), this represents normal volume ; hippocampal volume measures 8,259 mm³, 7.5% above the reference mean. With a Z-score of 0.84 (79.9th percentile), this represents normal volume ; whole brain volume measures 1,154,350 mm³, 12.2% above the reference mean. With a Z-score of 1.51 (93.5th percentile), this represents moderate enlargement; entorhinal cortex volume measures 3,481 mm³, 10.6% below the reference mean. With a Z-score of -0.82 (20.6th percentile), this represents normal volume ; fusiform gyrus volume measures 17,642 mm³, 3.1% below the reference mean. With a Z-score of -0.35 (36.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,051 mm³, 17.2% above the reference mean. With a Z-score of 1.53 (93.7th percentile), this represents moderate enlargement. ",
  "text_data": "Age is 69.0 years. Gender is Female. Education: 19 years. MMSE: 30.0. MoCA: 28.0. Logical Memory: 19.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.01 SUVR (normal ); Amyloid beta: 1297.00 pg/mL (normal ); Total tau: 146.00 pg/mL (mild reduced); Phosphorylated tau: 12.81 pg/mL (mild reduced). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The brain volume measurements show normal or above-average volumes in most regions, except for a mild reduction in the entorhinal cortex (10.6% below reference mean, Z-score -0.82). However, cognitive scores (MMSE 30, MoCA 28) are intact, and biomarkers (Aβ normal, T-tau/P-tau mildly reduced, AV45 normal) do not indicate Alzheimer's pathology.  \n\n**Diagnosis:** **CN (Cognitively Normal)**  \n**Confidence:** **High** (No significant structural or biomarker evidence of neurodegeneration or cognitive impairment.)",
  "timestamp": "2025-07-25T23:14:41.209005"
}