{
  "ptid_time": "014_S_6199_2018-02-21",
  "img_path": "/data/qiuhui/data/adni/images/014_S_6199/2018-02-21/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 76,956 mm³, 156.3% above the reference mean. With a Z-score of 3.71 (100.0th percentile), this represents profound enlargement; hippocampal volume measures 7,057 mm³, 12.1% below the reference mean. With a Z-score of -1.21 (11.3th percentile), this represents mild atrophy; whole brain volume measures 1,062,220 mm³, 6.4% below the reference mean. With a Z-score of -0.90 (18.3th percentile), this represents normal volume ; entorhinal cortex volume measures 4,377 mm³, 2.7% above the reference mean. With a Z-score of 0.19 (57.3th percentile), this represents normal volume ; fusiform gyrus volume measures 21,873 mm³, 9.9% above the reference mean. With a Z-score of 0.82 (79.4th percentile), this represents normal volume ; middle temporal gyrus volume measures 19,166 mm³, 14.5% below the reference mean. With a Z-score of -1.19 (11.6th percentile), this represents mild atrophy. ",
  "text_data": "Age is 69.1 years. Gender is Male. Education: 16 years. Handedness: Right. Race: White. MMSE: 28.0. MoCA: 20.0. Logical Memory: 11.0. APOEε4 alleles: 2.0. Biomarker levels: Flobetaben (FBB): 1.40 SUVR (profound elevated). ",
  "true_diagnosis": "Diagnosis: CN.",
  "gpt_diagnosis": "**Reasoning:** The data shows profound ventricular enlargement (Z-score 3.71) and mild hippocampal atrophy (Z-score -1.21), which are structural changes often seen in Alzheimer's disease. The MoCA score of 20 (below the typical cutoff of 26) suggests cognitive impairment, while the MMSE of 28 is still within normal range, indicating possible early-stage decline. The presence of two APOE4 alleles further increases Alzheimer's risk.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)** (likely due to Alzheimer's pathology)  \n**Confidence:** **Medium** (imaging and MoCA support MCI, but MMSE is borderline normal; clinical correlation needed for progression assessment)",
  "timestamp": "2025-07-25T23:59:12.679265"
}