{
  "ptid_time": "137_S_4631_2014-06-09",
  "img_path": "/data/qiuhui/data/adni/images/137_S_4631/2014-06-09/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 35,809 mm³, 7.0% below the reference mean. With a Z-score of -0.17 (43.3th percentile), this represents normal volume ; hippocampal volume measures 8,007 mm³, 5.9% above the reference mean. With a Z-score of 0.58 (71.8th percentile), this represents normal volume ; whole brain volume measures 1,166,820 mm³, 8.1% above the reference mean. With a Z-score of 1.05 (85.3th percentile), this represents mild enlargement; entorhinal cortex volume measures 3,683 mm³, 10.2% below the reference mean. With a Z-score of -0.69 (24.5th percentile), this represents normal volume ; fusiform gyrus volume measures 20,727 mm³, 10.0% above the reference mean. With a Z-score of 0.85 (80.3th percentile), this represents normal volume ; middle temporal gyrus volume measures 24,000 mm³, 12.5% above the reference mean. With a Z-score of 1.12 (86.9th percentile), this represents mild enlargement. ",
  "text_data": "Age is 71.5 years. Gender is Male. Education: 20 years. MMSE: 29.0. MoCA: 27.0. Logical Memory: 7.0. APOEε4 alleles: 0.0. Biomarker levels: Florbetapir (AV45): 1.48 SUVR (profound elevated); Amyloid beta: 612.40 pg/mL (mild reduced); Total tau: 325.30 pg/mL (mild elevated); Phosphorylated tau: 35.85 pg/mL (moderate elevated). ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "Reasoning: The brain volume measurements are largely within normal ranges or mildly enlarged, with only the entorhinal cortex showing a slight reduction (10.2% below mean, Z-score -0.69). Cognitive scores (MMSE 29, MoCA 27) are normal, but biomarkers (Aβ mildly reduced, T-tau mildly elevated, P-tau moderately elevated, AV45 profoundly elevated) suggest amyloid pathology and neurodegeneration.  \nDiagnosis: **MCI (Mild Cognitive Impairment)**  \nConfidence: **Medium** (Biomarkers indicate early AD pathology, but cognitive scores remain intact, and structural atrophy is minimal.)",
  "timestamp": "2025-07-26T16:39:29.773868"
}