{
  "ptid_time": "002_S_4473_2013-02-05",
  "img_path": "/data/qiuhui/data/adni/images/002_S_4473/2013-02-05/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 79,429 mm³, 106.2% above the reference mean. With a Z-score of 2.54 (99.5th percentile), this represents significant enlargement; whole brain volume measures 1,169,360 mm³, 8.3% above the reference mean. With a Z-score of 1.08 (86.0th percentile), this represents mild enlargement; entorhinal cortex volume measures 4,440 mm³, 8.3% above the reference mean. With a Z-score of 0.56 (71.3th percentile), this represents normal volume ; fusiform gyrus volume measures 20,343 mm³, 8.0% above the reference mean. With a Z-score of 0.68 (75.2th percentile), this represents normal volume ; middle temporal gyrus volume measures 22,484 mm³, 5.4% above the reference mean. With a Z-score of 0.48 (68.5th percentile), this represents normal volume . ",
  "text_data": "Age is 75.8 years. Gender is Male. Education: 16 years. MMSE: 29.0. MoCA: 23.0. Logical Memory: 14.0. Laboratory findings: Vitamin B12: 1245.00 (profound elevated); Total Bilirubin: 0.90 (significant elevated); Direct Bilirubin: 0.30 (significant elevated); GGT: 128.00 (profound elevated); ALT (SGPT): 93.00 (profound elevated); AST (SGOT): 56.00 (profound elevated). APOEε4 alleles: 1.0. ",
  "true_diagnosis": "Diagnosis: MCI.",
  "gpt_diagnosis": "**Reasoning:** The ventricular volume is significantly enlarged (Z-score 2.54), which is often seen in neurodegenerative conditions like Alzheimer's disease. However, whole brain volume is mildly enlarged, and key regions (entorhinal cortex, fusiform gyrus, middle temporal gyrus) are within normal ranges. Cognitive scores show a discrepancy (MMSE 29 normal, MoCA 23 borderline impaired), suggesting possible mild cognitive impairment (MCI).  \n\n**Diagnosis:** **MCI** (Mild Cognitive Impairment)  \n**Confidence:** **Medium** (due to conflicting imaging and cognitive findings; ventricular enlargement raises concern, but preserved regional volumes and high MMSE complicate the picture).",
  "timestamp": "2025-07-25T20:28:26.282054"
}