{
  "ptid_time": "136_S_0194_2006-10-16",
  "img_path": "/data/qiuhui/data/adni/images/136_S_0194/2006-10-16/t1.nii.gz",
  "img_finding": "Image findings: ventricular volume measures 22,610 mm³, 38.8% below the reference mean. With a Z-score of -1.05 (14.7th percentile), this represents mild atrophy; hippocampal volume measures 5,507 mm³, 15.2% below the reference mean. With a Z-score of -1.22 (11.1th percentile), this represents mild atrophy; whole brain volume measures 828,271 mm³, 10.8% below the reference mean. With a Z-score of -1.29 (9.8th percentile), this represents mild atrophy; entorhinal cortex volume measures 2,897 mm³, 16.3% below the reference mean. With a Z-score of -0.88 (18.9th percentile), this represents normal volume ; fusiform gyrus volume measures 14,739 mm³, 8.5% below the reference mean. With a Z-score of -0.64 (26.1th percentile), this represents normal volume ; middle temporal gyrus volume measures 13,651 mm³, 24.3% below the reference mean. With a Z-score of -2.16 (1.5th percentile), this represents significant atrophy. ",
  "text_data": "Age is 81.0 years. Gender is Female. Education: 12 years. MMSE: 24.0. APOEε4 alleles: 0.0. ",
  "true_diagnosis": "Diagnosis: AD.",
  "gpt_diagnosis": "**Reasoning:** The patient shows mild atrophy in the hippocampus and whole brain, with significant atrophy in the middle temporal gyrus—a key region for Alzheimer's pathology. The MMSE score of 24 suggests mild cognitive impairment, and the absence of APOE4 reduces but does not eliminate Alzheimer's risk given the structural findings.  \n\n**Diagnosis:** **Mild Cognitive Impairment (MCI)**  \n**Confidence:** **Medium** (Structural changes are concerning, but clinical correlation is needed to rule out other causes of atrophy.)",
  "timestamp": "2025-07-26T15:58:40.513006"
}