I met Mr. Osman MEWAEL born on 16.05.1987, 37 years old, who is being followed like his brother for oculocutaneous albinism.  
Mr. MEWAEL is the second child in the family with an older brother in good health, and a younger brother also affected born in 1989. He also has two half-sisters who are not affected from his mother's second marriage.  
There was no known consanguinity between his parents. There are no very specific antecedents in the family.  
Mr. Osman MEWAEL presents a classic form of oculocutaneous albinism with white skin, very pale blonde hair, and visual impairment with nystagmus. His visual acuity is around 2/10. He has no known pulmonary problems.  
He presented some epistaxis in childhood and would have had some very intermittent digestive bleeding.  
It is very likely an autosomal recessive disease, with each parent being a carrier of a heterozygous mutation. The association of intermittent digestive bleeding may raise the hypothesis of Hermansky-Pudlak syndrome.  
It is important to specify this as it would require closer digestive monitoring as well as pulmonary monitoring (risk of pulmonary fibrosis).  
We took the opportunity of this consultation to take samples from him and his brother to send DNA for the Albinism panel. A complete blood count has also been requested.  
In summary:  
Oculocutaneous albinism probably autosomal recessive with suspicion of Hermansky-Pudlak syndrome.  
I will keep you informed of the follow-up.  
Best regards.