[
    {
        "reference": "MATKRKVIITCAPTGAIHTPSMSPYLPVTPQQIGDAALAAAKEGAAIIHLHARDPDDGHPTQDPAVFQEFLPRIKAECDAVINLTTGGSPHMTVAERLKPAHHFQPEVASLNMGSMNFGLYPMLERFKELKYDWERKHLENSRDLVFKNTFADIEYILTSCGANGTRFEFECYDISHLYNLAHFVDRGLAKPPFFVQSVFGLLGGIGAHPEDLAHMRRTADRLFGKDYVWSILGAGRNQIPLASIGVAQGSNARVGLEDSLWIEPGKLAESSAAQVRKIRQVIEGLSLDIATPAEAREMLQLKGAANTNF",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Aldolase_TIM sharing conserved structural features; 2. The protein must be able to perform the cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043720",
                "GO-Name": "3-keto-5-aminohexanoate cleavage activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 310
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR008567",
                "InterPro-Name": "BKACE",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 303
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 310
            },
            {
                "InterPro-ID": "IPR008567",
                "InterPro-Name": "BKACE",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 302
            }
        ],
        "ipr_mapped": [
            101
        ],
        "response#1": "MINENILLGDRFIESIDLNNKKIKDKNIINKKEENKGEGEEKENKEINENVNKENIIEENENITNNEKRQEKKKEKIKIEEKKEIEEKEIKEKEKKIEKEKEEEEKNKNEKDKKENEKEDINNKENKYNIKKKKNKKKKKEKEKEEKEKVKEENIIEEKDKEEKKEEKEDNKNGNEKKIIEKDEIKKEEEEKKLEENIDINKDIIIKHKEKEKEEKEEEKENNIFNSINPINSSNTNININKEKIIKQDNLKESINSIDINNSINNNNNIINNNNNNNSNNSNKNIDNNIINNNINNKKSLIDNNINSNSIINNDNNIINNTINNNNIIKEKEIKEEIEKLKVIEEVNKNINKDEEINKNINE",
        "response#2": "MSEKKKPFYKKWWFWLILFLIIGGIISNISSDSSKTKTKEEKIAEEKRQEEERIAEEKRQEEERIAEEKRQEEERIAEEKRQEEERIAEEKRQEEERIAEEKRQEEERIAKEKEEQSKLENLAKEYVLSRLKDPDSAEFRNTRVEENIIGYKVVIGEVNAKNSYGAYTGFKTFYVIVSNGEVSVKDDEDNNPELKNLKNEACEIFFRNK",
        "response#3": "VPERLTPEERAAREARAAAERARREAEERARAAEEERLRAEREAAERRAAEERAAAERERREREERAAAEERARRRAEEERRRAEAAAREAEERRAREERERREREEREAAEARAREAERRREEARTREAARAEEERRRAEEAARREAARRAAEEEARARERVRREAAEREREAARRAAEAAERERAAREAEARARAAEAARRAEEARARAAAPPPAPPPAPPPAPPPDPDPDPDPDPDPDPDPDPDPDPDPPTDPDPDPDPPTDPDPDPDPDPDPDPDPPTDPPTDPSPPPTDPPTDPPTDPT"
    },
    {
        "reference": "MSEEVQERIWILITPDKCSGCRLCEVTCSLEHEGIIWPEASRIRVFELFPGINVPHTCVQCPDYPCVNACPTNALSVDEKTGAVVVNEEKCITCGACVLACPGKVPRIPAGKGSVVICDLCGGNPKCVEICHEAGHDALKIVTGNYRPIYRTFAKDPQEKSLDIARKVFGEDF",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd that are essential for its biological function; 2. The protein should contain 4Fe4S_Fe_S_CS that is preserved across related proteins; 3. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            79,
            183,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 40
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 48,
                "End": 80
            },
            {
                "InterPro-ID": "IPR017900",
                "InterPro-Name": "4Fe4S_Fe_S_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 91,
                "End": 102
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 54,
                "End": 132
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 82,
                "End": 111
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 28
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 40
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 48,
                "End": 80
            },
            {
                "InterPro-ID": "IPR017900",
                "InterPro-Name": "4Fe4S_Fe_S_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 91,
                "End": 102
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 54,
                "End": 132
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 82,
                "End": 111
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 28
            },
            {
                "InterPro-ID": "IPR050294",
                "InterPro-Name": "RnfB_subfamily",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 134
            }
        ],
        "ipr_mapped": [
            769,
            659
        ],
        "response#1": "TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAQLRGVVAAAGDLLKGLGVTGKHMFAKKVTEQYPEEKPVVSPRFRGRHVLTRDPETGEEKCIGCELCAWACPADAIYVEAADNTEEERYSGERYGRVYQINYLRCIGCGLCVEACPTRALTMTNDYELADEKRGDLIYTKEQLLAPLPEEVRAPNPHPMAGVTDKDYYLGAAAAKPEEAEAPEAETPEETTEEKETE",
        "response#2": "MATVAQITHFFKSLMLTELLKGLALTGRYFFARKITVQYPEEKTPISPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITIESETRDDNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETNILEYHGEKRGDLYFDKDMLLAVGDRYEPEIAAAKAAAAAEAEAAPEAEAAPEAEAEPEAEAAPEAEAAPEAEAEAEAAPEAEAAPEAEAAPEAEAAPEAEAAPEAEAEPEAEAEPAPEAEPAPEAEPAPEAEPAPEAEPAPEAEPAPEA",
        "response#3": "TDPDTDPDTDPDTDPDTDTDPDTDPDTDTDPDTDTDPDPTDPDTDTDTDTDTDTDPDTDTDPDTDTDPDTDTDTDTDTDTDTDTDTDTDTDTDPDTDTDTDPTPTPTTPTPTPTPTTPTPTTPTPTPTTPTPTPTPTPTTPTPTPTPTTPTPTPTPTPTPTPTPTPMDYTRAAGSLLLREFAGAFALGMRYFFSPKATLNYPFEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIEAEPRDDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETREELYYDKAKLLANGDRWEREIARNIALDAPYRLPGGAR"
    },
    {
        "reference": "MHALRSSVLALWLCLHVSVRAWMTYRSANGLDEYEPEDRIIFLGTKWCGNGNVAEGPEDLGPLKETDACCREHDMCPDLIAAGQSKHGLTNTASYTRLNCGCDEKFYNCLKNSAETGSGAVRFTYFTVLGTKCYRNEHPLICVKKGWFSCSKYELDKSQPKRYQWFDVSSNFAFPRMLT",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PLipase_A2_dom, PLipase_A2_dom that are essential for its biological function; 2. The protein should be classified within PLipase_A2_dom_sf, PLipase_A2_dom_sf sharing conserved structural features; 3. The protein must have PLipase_A2_His_AS that is conserved among related catalytic enzymes; 4. The protein must be able to perform the cation binding,hydrolase activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            },
            {
                "GO-ID": "GO:0004623",
                "GO-Name": " phospholipase A2 activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            183,
            19,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR033113",
                "InterPro-Name": "PLipase_A2_His_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 69,
                "End": 76
            },
            {
                "InterPro-ID": "IPR016090",
                "InterPro-Name": "PLipase_A2_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 136
            },
            {
                "InterPro-ID": "IPR036444",
                "InterPro-Name": "PLipase_A2_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 40,
                "End": 171
            },
            {
                "InterPro-ID": "IPR016090",
                "InterPro-Name": "PLipase_A2_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 38,
                "End": 154
            },
            {
                "InterPro-ID": "IPR036444",
                "InterPro-Name": "PLipase_A2_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 167
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR033113",
                "InterPro-Name": "PLipase_A2_His_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 69,
                "End": 76
            },
            {
                "InterPro-ID": "IPR016090",
                "InterPro-Name": "PLipase_A2_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 136
            },
            {
                "InterPro-ID": "IPR036444",
                "InterPro-Name": "PLipase_A2_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 40,
                "End": 171
            },
            {
                "InterPro-ID": "IPR016090",
                "InterPro-Name": "PLipase_A2_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 38,
                "End": 154
            },
            {
                "InterPro-ID": "IPR036444",
                "InterPro-Name": "PLipase_A2_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 167
            }
        ],
        "ipr_mapped": [
            828,
            829,
            830
        ],
        "response#1": "YNRYEMTNDEFDEEDCGDNEECTPAETTGRGGGQSYVSYDTTYYEGDPQCGDGDDYPEDDGEGDEQCEEGDDCEDDEDEEDEDCYDEDEDSYGGECPEGDEDEDEGDDCYELEGECEECYDETLDGGGEYDEDDGVEEGDGDGEGECGDEEGDEDDCDECECGDCCGDECECCEEECDGGEGGGDPYGGEETGGDGDCDGYCECCD",
        "response#2": "MLTGTACGCARRRGPGPRRPCFGPAVPPALGRRGPDCDCECECDWSCDCDDCNPSDDPDCDCDCEGDDCDCGCDCEDCEDDDCDCDCDDCDDCDDCCECDDCCDCDDCECDDDCECDCDDCECDCECDCECDDCDDCDDCDDCCDCDDCDDDCECDDDCECDCECDDCDCECDCDDCCDCDDCDDCDCECDCGCCDCDCDGECDCGCGDAAPDAARAAARAAGAAARAAGAAAGAAARAARAAGAAAGAAARRLGRRAVRGHMLNLFQFGKMIKFETKRSWKDYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYGKLTGCDPKKDFYSYSWKDKTIICGGGNPCLKEICECDKAAAICFRSSEYTDRYKNIDTKKFCR",
        "response#3": "HLLEFGKMIKFETGKEAVKFYAFYGCYCGWGGRGKPKDATDRCCFVHDCCYGKLTGCNPKKDFYSYSWKEKTITCGGGTPCEKEICECDKAAAICFRDNLDTYNYDKYKKYGGNGGGGGGGDGGGGGGGCGGCGGCCGCGDGCDDCDGCGDCGDDCDDDGCGGCDDCDGGGDCGGCDGCGGCGCCGGCDGGDCDGCGGCDGCDGCDGCGCCDGGCDGCDCGCDGDDGCGDCGDCCDCDGCDCGDGCDDGDCGGGCDDCGDGCGGCDCDCGDCDGCDGCDCDGGGCDCGCGGCDGDCDDCDDCDGCDGCDGCCGDGGDHGDGCDGCDDCCGCCGGDGCF"
    },
    {
        "reference": "MISTPEPLHAGHILTPFCCGVDSIDNWLKQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDPIPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLVESV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016747",
                "GO-Name": "acyltransferase activity, transferring groups other than amino-acyl groups "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 151
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 151
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 85,
                "End": 143
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MTRPPPAPRPPAPGRRPRAAPADRPARAARRALAADRRVRLLGGVVRALDPAAAPPAAARPDARTAPLVLAASGPLRLAVLLAAAGDPAAAAPFLEARAAAALRRAGVASYRPPPEPPAAPDRPDPPGPGPGPGPGPGPGPGPGPGPPDRPDRPDRPARPDPPDRPDRPDRPDRPAGRPGGPDRSAGPDRPDRPAGPDRPAGPDRPDARPDRAGPDRPDRPDRPGTDRPAGRPARPDRPAGPDRSGTARPDRPDRPAGPGRPAGRPDGAAGPGPDRPDRPAAAAAGPAAAGPRPPARPADRTPAERAARRWRERAVALHGLPGPAAGPLTRGAAAALNRLAPLAHATARRLARAGELPGPGYGEPARVDRVAALAEAQAERLLRHLAAR",
        "response#2": "MTTTTTRPTPPPAPVTVHVLAAAPTRTTRPDRTTRTDRATRPTRTTDPTRPTRTRRTPTAPPTRPDRTTRPDRTTRPDRITHRTRSGPHSPQLTARLHLHAPTGHTDAPALTAALHDAALHHAARTARTAPPTATRITLRVTPHRRAPPTPPPPHTTHPTPPTPTRAAPAAPHTPRTPTPTPALLRLHAALHLTAHHHPHLTVLTATAAAHAADTRPAAALAADLAAALRTAPPPRLRARPDPATLRAAHTAALHALTHHPHAPAHPPAPGQPAPRHAPRPPAAAPAPRPHRPQAPNRRTPTTAPPPAAPPAPAAAPPAAASAARPGAAPPAPHPAPAPAAPARPCPACAARAALTALTRTHLTAAGTAPTDPTDPTAALLAAALTALQHAHHRP",
        "response#3": "MTTPDRTPDRTPDRTPGRTPDTATRADLHAALTAYCAALADLTAAHHAAITHRDTAHLTALTADLATLHTALHTRHPHPAPRPPAAAHTLATAAHHLHRTATPPPPPTPTPTPPTPAELRAALHTALAHHTTALTALATHHHHPAHLAALPDPHTPTLTAAAHHLTTALTALTAHHHTTAHHLAAHWATLHHTPPPPLPPPPTPHPHTALHTALATHAHHTHHITADLTTLHTALTHRTTPPPPPPTPHTPHTPTPPHTADIATLHAALHTLTTHHTHHTHTLATAHTTLTAALADLTAYNRHTTARLAALATALHRTTTPPPTPPPTTPPPPPPPRPATTPPRRHPPPPTPTPPPPPPPPPPPPPPPPPPPPPPTPHR"
    },
    {
        "reference": "MTVPAARSGRKVYFIGLNAVPFLPLVAGLLRTYAEQDPRVAAGYDFQEPVFLVDGVQEMAAGITDPDVLALSCYVWNFRRQMKVARLVKERHPGMLVVAGGPHVPDRPGDFFARHPYVDVLVHGEGETAFRELLIERLADHPDYTRVPGVSVRHGTEAVPGRPAERLPRRIETPSPYLLGVMDGAVATCRQRDLRFYALWETNRGCPYSCAFCDWGSATMSALRLFDAERLQEEIEWFAEHDVEDLFVCDANFGILPRDLEIARALADARAATGAPKLIRVNFAKNSNDRVFEISKTWHDADLLMGTTLSMQSTDLDVLEAIDRKNIGLENYRKLQQRYATENIHTYTELILGLPLESPRSFRDGIGSLLEAGNHEDIRVYEFGILPNAPINTPEKIAGYGLRTVPKRLYVEEPGTPDDEAETVDMVMETNAMSRDEWVDCFGFVQAVQFLHNGCYTRYLSMYLRQRHDIGYTAFYERLQQYFGARPDTVLGSIYLRMRKLYHDYIDIPELPLANLVASQPDMAADLARYGKRRGWTIDNWGWLRIANDFERTYTELRDFVAALGVDDTSDPDLAEVFRFQQDVMLRPDYDPAAGRTTEYTADWPGYFTTGELRRRPVRMRLADQRFGANGRYTPVPGDLKAFARAAIGPSYPVSRIGHYRHRFEAAEVTSPAEPVLTEQR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, rSAM that are essential for its biological function; 2. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding,methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0031419",
                "GO-Name": " cobalamin binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            79,
            183,
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 196,
                "End": 414
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 192,
                "End": 417
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036724",
                "InterPro-Name": "Cobalamin-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 64,
                "End": 139
            },
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 196,
                "End": 414
            },
            {
                "InterPro-ID": "IPR023404",
                "InterPro-Name": "rSAM_horseshoe",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 195,
                "End": 395
            },
            {
                "InterPro-ID": "IPR006158",
                "InterPro-Name": "Cobalamin-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 144
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 192,
                "End": 417
            },
            {
                "InterPro-ID": "IPR006158",
                "InterPro-Name": "Cobalamin-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 64,
                "End": 134
            },
            {
                "InterPro-ID": "IPR034514",
                "InterPro-Name": "ThnK-like",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 681
            },
            {
                "InterPro-ID": "IPR051198",
                "InterPro-Name": "Tetrapyrrole_Bchl_Biosynth_MTs",
                "InterPro-Type": "FAMILY",
                "Beg": 61,
                "End": 403
            },
            {
                "InterPro-ID": "IPR034466",
                "InterPro-Name": "Methyltransferase_Class_B",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 681
            }
        ],
        "ipr_mapped": [
            195,
            196
        ],
        "response#1": "MLPPQEVTREEGGGCGGRGGGDNHRQRRQGRPDGAAEAGGARGRHPAAAAQHQRHRQHHQPRRARQQQPERQPQHHAHRQQQPRRRHRRHHHRGNPQHHHPRHQPQHQRQPQHQRHPHRQHHHPHRQPQRHHHPHHPRRQRRHHQQRPQPHRQRRRHHQHPRPHPRRHHQPQRQRHHHQQPPQPQHRHQPRRHQPQLRHQPHHRHQHQHHHQHRHQQPQQPHHPHPQHQQQHRRHQQRRHPGQQHHHQQQQHRRQQRRQPARHRPPRQRP",
        "response#2": "GHGQEHGQGHGQGHGQEHGQGQGHGQEHGHEHGQGHGQEHGQGHGQGHGQEHGQGHGQEHGQGHGQGHGQEHGQGHGQEHGQEHGQGHGQEHGQGHGQEHGQGHGQGHGQGHGQRQGQGQGQGQGQGQGQGQGQGQGQEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEFNPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAQGTGRAA",
        "response#3": "AQQPRRRQHGRRPRRPHPRHRHPHRHHRQLHRQHHPHHHPHPPQHPPRHPHPQPHHPPRLHHRQQQHHRPHQHPPHHPPRQRRHPQQHPPPHQQQRHHPQPHHPQQQQRHHPQHHHHQQQRRRRQHQRPQRQRHRPRHPPPPRLRPRPPHPPRHQQQQQHQQPHRHPQQRQQRRQQQQQHPQPHRRHRRQHRRPHRRGHRHPHQQPRRQPHQRHPQQHRRRRPQRHAAR"
    },
    {
        "reference": "MLRYRQVVGLLQRRNFSAGATSNGSGSSGGDKSGEDLHPIRRTLRLLGNDMRKVKEFFVPKEPETEKVPIPTQSQFHFSGERDKSKEATVPDDFQTHCDVLIIGGGGVGSSIAYWLKEKARDGLNVVVVEKDDTYAQSATRVSVGGLCQQFSLPENIQMSLFAADFLRSARKHFGEEVPLQFTPHGHLMLAGEEHAESLKRSSQLQNELGARNELLTADRLTARFPWLNTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGSNEGAYTGLEKAVIQLPDGTRRTCKFALCVISAGASSEQIARLARIGVGPGILRVPLPINARKRYMYAINSQAQSAPGMNMPMTIDPSGIFIRRDGLGGNYICVQDSTEEYNSAMIDPQYFAQHIRPHLYNRIPVLGEAQVVDSWAGCYDHNVYDENGILGAHPYYNNLYLATGFSGHGVQQSLAVGRAISELIMDGQFRTIDLSRLSFDRLIVDQPMFELNNVLS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FAD-dep_OxRdtase that are essential for its biological function; 2. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006076",
                "InterPro-Name": "FAD-dep_OxRdtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 99,
                "End": 482
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 99,
                "End": 485
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 97,
                "End": 509
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006076",
                "InterPro-Name": "FAD-dep_OxRdtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 99,
                "End": 482
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 99,
                "End": 485
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 97,
                "End": 509
            }
        ],
        "ipr_mapped": [
            43,
            270
        ],
        "response#1": "MVIPRLKNKVAIITGGASGIGKATALLFAEEGAKVVIADIKEEEGKKTVEEIKKKGGEAIFIKTDVSKEEEVKKMVEKTVEKFGKIDILVNNAGIEIVKPVTELTEEEWDRVINVNLKGVFLCSKYVAKYMIKNKWGRIINISSIAGLVALPYHAPYVASKHGVIGFTKVMALELAPYNITVNAICPGPVDTPLLRKEFELQEKNGRNKEELEKEALERIPLKRVGKPEEIAYVVLFLASDEASYITGQAIVVDGGYTVSLR",
        "response#2": "MTRTVIITGAGRGLGRAHALYFAARGDRVVVNDLAAPEAAGADYPTPATAADLDAVVAEIRAAGGEAVADTGDVSTAAGAERIVATAADAFGPIDVLVNNAAILRDKTFRRMTDADWDRVLAVHLRGTFHATRAAWPQMVARGGGRILNTSSGAGLFGNRGQANYGAAKMGVVGLTRTLALEGARHGIRVNAVAPNAATRMTEHITDPAARARITERLAETFRPELTAPLMAWLASDAAARVTGRVFAVAAEEIGLYKTAPIYATPAAPLTREAVAAGWDAIEADRDLLERSDADQALFDDFAIRMAEAGDAAPEPAP",
        "response#3": "MADEKLHVLINNAGVMATPYSTTKDGFELQFGTNHLGHFLLTNLLLPKLKASAPSRIVNVSSEGHRFGKIQFDDLNFEKGKKSYSPFAAYGQSKLANILFTYELARRLKAENSTVTANALHPGVIVTNLYRHTNFFMKKVVYTVLWPFYKSPEQGAATTLYLAASPEVASVSGKYLSDCGEVYKSPEQGAATTLYLAASPEVASVSGKYLSDCVEVGSPAPHAYDKDAAEKLWALSEKLTGIKYE"
    },
    {
        "reference": "MQTYLSTKSIEYYLKELKEIFSQIWLKPSEIEKRCEELFKRSKEFDYKRILVSGETDNTTLYVIEDSSKIHVFSPNRDLRENPLLMRWHPSWYEIESKEIYYKCFLSCEELYEHLELPTVTLVNLCVIENFPIPRLNLSTGTLSSYLRKEQLAKVELIDMQVGTTINQIIKNLLDSQPDIIGLSVNFGQKKLAFEILDLIYSHIENGDLSSIITVGNVIPSFSPEQFFERYPSLLICDKEGEYTLRDLIKMLKKELKLDEVNGISYVDESGEVKHNVAETVNFKEEVPTPSLDILGEISKFRGALTLETSRGCDYSRCTFCPRDHKLRSWRPLSVEQTLKQLDDILRAGKHFNIKPHIYMADEEFIGELPNGTEAQRIIDICEGLLKREEKIKFDFAARADSVYEPKRTKEWNVERLKMWHYCALAGADRIFIGVESGSNQQLKRYGKGTTSEQNIIALRLVSALGINLRIGFIMFDQLMKGLDNLKENLDFLERTDALMKPIDIGDMTYEELYDKLLNDKEFIEKHKTGKPVYTIVSYMLASMEILMNTPYSRMVQLTERKEEVNLIMNDGKPDMNMGRYATSFVDKTNGNLSEACQMWIDSNFGVMYTIKSLHKVANPREKKKLYSYMETHREISHFLLKYLVYNLSPDKESQIILSDFLRMHSMEHILDNSKINVGDGSKENILNVMTNWQLIMEKLLRDVEADLNKGIITDSEDHRLHNTLKRWFSDMGNWSLINAYELN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, rSAM, rSAM, rSAM that are essential for its biological function; 2. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0031419",
                "GO-Name": " cobalamin binding "
            },
            {
                "GO-ID": "GO:0016853",
                "GO-Name": " isomerase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            79,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 303,
                "End": 529
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 299,
                "End": 545
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 308,
                "End": 470
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 744
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 303,
                "End": 529
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 299,
                "End": 545
            },
            {
                "InterPro-ID": "IPR023404",
                "InterPro-Name": "rSAM_horseshoe",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 302,
                "End": 476
            },
            {
                "InterPro-ID": "IPR006158",
                "InterPro-Name": "Cobalamin-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 119,
                "End": 259
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 308,
                "End": 470
            },
            {
                "InterPro-ID": "IPR034532",
                "InterPro-Name": "OxsB-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 744
            },
            {
                "InterPro-ID": "IPR051198",
                "InterPro-Name": "Tetrapyrrole_Bchl_Biosynth_MTs",
                "InterPro-Type": "FAMILY",
                "Beg": 122,
                "End": 497
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 744
            }
        ],
        "ipr_mapped": [
            195,
            196
        ],
        "response#1": "QDQDQEEDQEEDQEEDQEEDQDQDQEEDQEEDQDQDQDQEEDQDQDQDQDQDQDQEEDQEEEDQEEDQEEDQEEEEDQDQDQDQEEDQDQDQDQDQDQDQDQEEDQEEDQEEEEDQDQDQEEDQDQDQDQEEDQEEDQEEDQDQDQDQDQEEDQEEDQEEDQDQDQDQDQDQDHHHHHHHHHHHHHHPPPPPPPPTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTPPPPPPPPPPPPPPPPPPPPPPPPPPPS",
        "response#2": "MKRAFLIREQYYGKKVQLSTLMNLKSGACPEDCKYCSQSRYNTDVERYSLMTEEEVVEGAKKAEANGSSRFCMVASWRGPNEKEVDQVANMVKRIKEETSLEVCACLGMLNETQAKKLKEAGLDRYNHHLNTSKEFYGNVISDTHTYEERVDTVLESKKAGLSVCSGGIFGLGETMEDRANMAFELQKLDPDSIPLNFLVKIEGTPLEGQEDLTPYECLRTLALFRFINPTKEIRLSGGREINLRSLQPLALYAANSIFVGDYLTTAGQPAELDYQMIEDLGFEVEEEVQTVHA",
        "response#3": "HHQHQHQRPHRHPPRPPRHRHRQQQRGHHGHRRRRHGHRHRHHRPPRPLHPPPPPPPRPRRHQRHHHHPQQQLHQRPGQQPPPRPPPPPPPRHHRQQQQGEQQQAHVGCRRHRRHHGHHQQHQQQHGREQRRHHGRQRQGQRRQGRRRHRRRGQQQQQGEQQQHQQRRRRHHPHPGHQHHQQRHHHPPPPPPPPQQQHPHHHHHGREHGRGRGRRRPPRHPPPPPQQPPRAHGRHHHRGGGQLPQRRRHHRHGRGQHHQQHQQQQQHQQHPPPPPPHPPPPPPPPPPPPPPHHPPHP"
    },
    {
        "reference": "MSSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRYLN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more HD/PDEase_dom, HD/PDEase_dom that are essential for its biological function; 2. The protein must be able to perform the hydrolase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            19,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR003607",
                "InterPro-Name": "HD/PDEase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 26,
                "End": 94
            },
            {
                "InterPro-ID": "IPR003607",
                "InterPro-Name": "HD/PDEase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 146
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR003607",
                "InterPro-Name": "HD/PDEase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 26,
                "End": 94
            },
            {
                "InterPro-ID": "IPR003607",
                "InterPro-Name": "HD/PDEase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 146
            }
        ],
        "ipr_mapped": [
            482
        ],
        "response#1": "MKLTWIGHSAFKLEANGKVILIDPFLSGNPAFEGLDLNKIPNEKVDYILLSHGHGDHVGDTVELAKKNNATVIAPFELASYLGSQGVEEKNIHGMNIGGSYEFDFGKVKLTQAFHSSSITREDGSIVYTGMPAGILLEIDGKKIYHAGDTALFSDMKLIGELNDIDVALLPIGDNFTMGPKDAALAVKWIKPKLVVPMHYNTFPLIEQDPYKFKELVEKEGVEVKILEPGESIEL",
        "response#2": "MPQPIRVRELERELEALEGRVEALEGRVAALEGLVEAWRRRAEELERREEALEGRVRELEGRLAAAEGAAREARGELARARGELAEARARERRLGARLARLRRRLRGERERWRAEREALAAQVRELEARRAALEGGAAALGERLAGAEAALEEARGRLEAARGALEAARGALEAARAEAEARERELEARQEAVRAGLEAALGRLREEVGGLRAREEALRAEAAALGGLRARLEEVERALEAARREVEALRGEAGRLRRAEGRLREALRAREARLRALEEALARAREEAERRGRELAELRRRLAELPPPERVEELEVQNQALLEENRRLERENRRLEEENRRLEELNRALRRENEALKRMLRGVYRPPPPPR",
        "response#3": "MKLTFLGHATVKLEIKGKVFLIDPFLSPKGTFDPAEAGVKPNPLLVNPDYLEKVKGEKVDYILLSHGHADHIGDTVELAKKTGATVIASFELANFLSWQGVENVHPMNIGGSYEFDDFKVTFTQAFHSSSIIDEETGKVVEKTPVYTGMPAGIVIEAEGKKIYFAGDTALFSDMKLIGELYDIDLAFLPIGDNFTMGPKEAALAVKWIKPKTVIPIHYNTFPVIEQDPEKFKEEVEKLGVKAEVIIPKPGETVEIKF"
    },
    {
        "reference": "MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASDVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVSGVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Homeodomain-like_sf sharing conserved structural features; 2. The protein must be able to perform the DNA-binding transcription factor activity,transcription cis-regulatory region binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity "
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": " transcription cis-regulatory region binding "
            }
        ],
        "go_f_mapped": [
            160,
            91
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 115
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050109",
                "InterPro-Name": "HTH-type_TetR-like_transc_reg",
                "InterPro-Type": "FAMILY",
                "Beg": 27,
                "End": 224
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 90
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 57
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 65,
                "End": 88
            },
            {
                "InterPro-ID": "IPR054129",
                "InterPro-Name": "DesT_TetR_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 218
            },
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 115
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 38,
                "End": 98
            },
            {
                "InterPro-ID": "IPR036271",
                "InterPro-Name": "Tet_transcr_reg_TetR-rel_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 110,
                "End": 222
            }
        ],
        "ipr_mapped": [
            408
        ],
        "response#1": "MFMMGEYNHNVDSKGRLIVPTKFREELGEQFVCTKGLDNCLFGYPLSEWQILEQKLSRLPLTKKDARAFVRFFFSGASECEMDKQGRLLIAPNLRQHAGLTKECVLIGVSNRFEIWDKNRWYDYINEAEDSFSDIAENLIDFDLDDTEVPEAEPEPAPAAAPEPAPEPAAEPAPEPAPAPEPAPAPEPAPPEPAPAPEPAPEPAPEPEPAAEPAPEPAPEPEPAPEPAPAPAPEPEPAPEPAPEPEPAPEPAPEPAPEPEPAPEPEPEAEPAAEPAPAEPAAEPAPEPPEAPAEPAPAPAPEPAPAPEAEPAAAPEAEPAPAAEPAEAVEPKAEEAKAAEDRVASLFDRLGKLRGKPEPRKPAGPRAPRPRKPVSAAKRAPVRRPRRR",
        "response#2": "MFLSKYRNRIDGKGRVSVPANFRAVLGQECDGQLTCYPSTIRNNCIEVCGTAHIEKLEQMISRLDPYSEERDAFETMFFGEAVQLSFDGEGRVSVPANFRRHAGIEEQACFVGKGVIFEIWQPANFEAYEAKAQQMARERRFSVPGSPIGGAPGQVAGIPGTRNRRPPERRTRLAARVAVGDRWRISGPWRADSGFPAALEESAPARAASPRCGGIPAKLSVSQGGTVMFLSKYRNRIDGKGRVSVPANFRAVLGQECDGQLTCYPSTITYNGTIRNNCIEVCGTAHIEKLEQMISRLDPYSEERDAFETMFFGEAVQLSFDGEGRVSVPANFRRHAGIEEQACFVGKGVIFEIWQPANFEAYEAKAQQMARERMNFS",
        "response#3": "MAFQRPAPTRPAYPPPGDVSSVRPDERVEARPYGVPASRRDATADPAGNVRMLSGASLHNLDSKGRLLVPARLREELGEQFVLTRGLDRCLFGYPLPEWEILEQKLSRLPLTNPDARDFVRLFFSGATECNMDSKGRLNVPTRYREQLGLNANGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKEDIEAEQSATETLSERLQDLSL"
    },
    {
        "reference": "MRFSASLLLALTGSAAASPIRAEEEIRVYDLPISLFDDLQGLDAAMKAAGREYIGTSLTVRNDFQEQNIIRTEFGSITPENAQKWDATEPNRGQFTFGSADQHMDWARQNGKHVRCHTLVWYSQLPGWVSNSGFNNATLQQVMQNHINQVMGRYRGRCNHWDVVNEAPRLMAMRLQIGEAYIPIAFRMAAQADPSAKLYYNDYNLEYLGPKVEGAARIVRLVKQYGARIDGVGYQAHLVTEPTPTQSTPTPSEEDLIKALRITADLGVDVAYTEIDIRMRTPSNAQKLQQLADAYYRVARSCMKVPRCVGMTIWGVTDRYSWVPNTFRGEGDALLWDSNYQRKAAYNAFLRGIQEPVN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031176",
                "GO-Name": "endo-1,4-beta-xylanase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 48,
                "End": 355
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 349
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 225,
                "End": 237
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 158,
                "End": 169
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 114,
                "End": 126
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 196,
                "End": 207
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 40,
                "End": 352
            },
            {
                "InterPro-ID": "IPR044846",
                "InterPro-Name": "GH10",
                "InterPro-Type": "FAMILY",
                "Beg": 63,
                "End": 351
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 83,
                "End": 353
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 48,
                "End": 355
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "MYEDNHVIAVNKPAGLLSVPARPGEPALDQLVKDYLRARGEKAYVGVVHRLDRDTSGVIVFAKTSKAASRLSEQFKERRKEYLALVRGVPEPPQGAIDAPIGRDPHDRKRMAVVTPTGKPATTRYEVVERFEVPVPKRYPTARYSLVRLVPETGRTHQLRVHMAHIRHPVVGDAKYGGRPNRLGLGRQALHAARLAFTHPTTGERLWFEAPLPDDLRRALDALRGH",
        "response#2": "MTEARERAAAYREAKARQAEAEAAAAAEAARLEAERRADEERRRRDEEARRAEAERRRRRAEAERERRRAEEERRRAEEEERRRPAPEPEPEPEPEPEPEPAPEPAPPAPAPDPKELEEQAKRAAQARLDAEQQREAEREAEEERRRTQSELDAAARAEDEARRKAAEERRAAEAQAEADAPPPAQSPPPPPPPPPPPPPPRPSRPRRPRRPPSPPPPPSPTSW",
        "response#3": "MTDAAPAARPDAAAAPPTPPPPATPAPAPPPPAPPPPAPPPPAPAPPPVPPDGDDDDDDDVPDLPDEDDDEPDDAALQAARDEAAALAARRDALAAQLAAAREAVDDVDAQLAAADVPDADREALAALEAELDERAAARDARPPARRAPGPRARARPPRRRPRRTRLLRGRRPRRARRPRRRRGRAPPRRRPPRRRPRRRRRRRGPP"
    },
    {
        "reference": "MHLASSLFLLATLPFGFAAGKGKGKGKDNSDVGLDVLAKKAGLKYFGAATDTPGQRERAGLEDKYPEYDRIMWHSPEFGSTTPTNGQKWLFVEPERGVFNFTEGDVVASKARQHGKLLRCHALVWHSQLAPWVEETEWTPEELRKVIVDHITAVAGHYKGQCYAWDVVNEALNEDGTYRESVFYKVLGEEYIKLAFETAAKVDPKAKLYYNDYNLEWPSAKTEGAKRIVKLLKDAKIPIHGVGLQAHLIAEQHPTLDDHIAAIRGFTQLGVEVALTELDIRLKTPATEENLALQREAYKNVVGACVQVCGCVGVTIWDFYDPFSWVPYFFEGEGAPLLWFEDFSKHPAYYGVVEALTNKTRRSKRSISDRRAKLLA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031176",
                "GO-Name": "endo-1,4-beta-xylanase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 360
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 35,
                "End": 355
            },
            {
                "InterPro-ID": "IPR044846",
                "InterPro-Name": "GH10",
                "InterPro-Type": "FAMILY",
                "Beg": 73,
                "End": 320
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 235,
                "End": 247
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 206,
                "End": 217
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 118,
                "End": 130
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 162,
                "End": 173
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 87,
                "End": 356
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 55,
                "End": 355
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 360
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "DEESSKESSEKEEKEEKDTDAKKKEKDTDAKKKEKEETKEEEKDKDTKKEETKKEEEKTEEEKDTEKEKEEKKEEKKEEEEKKEESEEKKKEEEAPPPPPTEEKKEEKKEEKKEEKKEAKKEDKKEEEKSPPPPTPTEEKKDDDKSGPVKLSKAAKAALAKKEAAEKAAAEAKAKEEAKAKEENKDKDDDDDEKKEEKKEEKEEKPATPPTPVSPTTGFTEKKKEVKEDLPPPSEEDQRKYQLNWDLLDKEPHRSILNFTRDMNTYYKSNKVLHENTDKEGFQWIDADNKENSVFSFIRYWKDKHLIVVSNFTPVVRENYKVGVPYKGKYKEVFDSDAEVYKGSNVGNRDVTVEDNVVTITLPPLATMVLEPI",
        "response#2": "MEENKENKEKKEETKENKEENKEKKENKEDKKEKKENKNQEKENNENQKKDEKQNKNEKNENQEKDEKQNNNENQKEDKKEKKKEKNKEKEKKNENKKEEKNKKKKKKKEKKKKEKKEKEKKKEEEKNEKNGNKNKNKNKNKEKSNEDDYYDIYDDENDDDETYSNNDDYNNDYDDNYNNTYDDEYYNNEVYSNDNEVYSNDEVYSYDEVYSNNEVYSYDEVYSNNEVYSNNEVYSNNNNNNNNNNNNNNNNYNDNEDYYDEEDDEDYDYSKFDKEEMRKIKKERKERKKKEKEERQKEKEKEKEEKREKKKERKK",
        "response#3": "MTTRRRPARQDRPRPAAAPRPAGPPARPDRHPGTARPAGRRPGTARPARPARRPGPAPPPARPRPAGAPRRAARPAPPPAPRPAGDRPRPVIRTGDDPARTAAVTCRPDPALLADRVLRTDPPGPDGAPDPVAVAAALFDLAGDDLGGLLLAATDDGTAAGWHCALDGTVTGPLFAPGDSADGPAAARARLRAAVPVRAAGTRTLRLTDPDGTRWTVHREPRGRVRLRADPPDPLRDPAAGLLALLLAPRPRPGPGR"
    },
    {
        "reference": "MRSIALALAAAPAVLAQSQLWGQCGGIGWNGPTTCVSGATCTKINDWYHQCLPGGNNNNPPPATTSQWTPPPAQTSSNPPPNNGGGGGNTLHEKFKARGKQYFGTEIDHYHLNNNQLMEIARREFGQITHENSMKWDATEPSRGSFSFGNADRVVDWATSNGKLIRGHTLLWHSQLPQWVQNINDRNTLTQVIENHVKTIMTRYKGKIFHYDVVNEILDENGGLRNSVFSRVLGEDFVGIAFRAARATDPDAKLYINDYNLDSANYAKTRGMINLVNKWVSQGVPIDGIGTQAHLAGPGGWNPASGVPAALQALAGANVKEVAITELDIQGAGANDYVTVANACLNVQKCVGITVWGVSDRDSWRSNENPLLYDGSYRPKAAYNALMNAL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0030248",
                "GO-Name": "cellulose binding "
            },
            {
                "GO-ID": "GO:0031176",
                "GO-Name": " endo-1,4-beta-xylanase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 94,
                "End": 390
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 91,
                "End": 388
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 94,
                "End": 390
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 165,
                "End": 177
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 282,
                "End": 294
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 252,
                "End": 263
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 208,
                "End": 219
            },
            {
                "InterPro-ID": "IPR035971",
                "InterPro-Name": "CBD_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 52
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 134,
                "End": 390
            },
            {
                "InterPro-ID": "IPR001000",
                "InterPro-Name": "GH10_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 85,
                "End": 389
            },
            {
                "InterPro-ID": "IPR000254",
                "InterPro-Name": "Cellulose-bd_dom_fun",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 52
            },
            {
                "InterPro-ID": "IPR000254",
                "InterPro-Name": "Cellulose-bd_dom_fun",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 48
            },
            {
                "InterPro-ID": "IPR000254",
                "InterPro-Name": "Cellulose-bd_dom_fun",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 51
            },
            {
                "InterPro-ID": "IPR044846",
                "InterPro-Name": "GH10",
                "InterPro-Type": "FAMILY",
                "Beg": 101,
                "End": 381
            },
            {
                "InterPro-ID": "IPR000254",
                "InterPro-Name": "Cellulose-bd_dom_fun",
                "InterPro-Type": "DOMAIN",
                "Beg": 16,
                "End": 52
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "MTGDDDRPADDRPADDRPADDRPAADDPAPRPAAADDPAPRPAAADDPAPRPAADDPPRPAADDPARDRAELDRARAERDRAEAERDRAEAERDRAEAERDRAEAERDRAEAERDRAEAERDRAEAERDRARAERDRAEAERDRAEAQRDRAEEDRDRAQRDRARAERDRAEAERDRAEEERDRAEEERDRAEAERDRAEAERDRVEEERDRAEAERDAAEAERERAEEERDRAERERDRAEEERERAERERDRAEEERERAEEQRDRAEEERDRAEEQRDRAEEERDRAEDRAEEERDRVEEERDRAEEERDRAEEERDRAEEERDAAEEERDRAEEERDRAEEERAAPPPPPPPSPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPSP",
        "response#2": "MFQVLRKFNNKNNNNNNNKNENKKEQENENEKKNKEQNKEKKNNENEQKNKNNNNNNNKNDNEKEHENEKNNDNDKNENKKEQENENENENENLNENKKDKKENKKNNNNNNDNKKKKKKKKKDDDDDDDDDDDDNNDDDDDDDDDDDDDDDDDDDDDDDDDNDNDDDNDNNNDDDDNDNDDNDNNDNDDNDNNDDDDDNDNDNDDDNDNNDDDDDNDNNDNNENEDKNENEKEKEKEKEKEKEKEKEKEKEKENKEKEKEKENEKEEDKEKEEKEKEKEKEKEKEKEKEKEKEKEEKEKEKEKEEEEEKKEKEKEEKELEEEEKKIEEEEKKMEEEEKKLEEEKEIKNNKNK",
        "response#3": "MTVTPTPGTPWPRPETPRPEPCTPEQARTELAALDAEVRELEQRAARGEQDPRTAAQLAAVRARRDAVAAALAAPAPSPSPSSPSPSPSPEPSPEPPAPSPPAPSPSPATESPAATESPATESPATAEREAAERAERERRAAEEQAARERAEAEAAARRRAEEERRRAEEERRREPERRRAEEERRAAEEAARERERREAPTPEPPEPPTPEPPEPPTPENPTPEPPEP"
    },
    {
        "reference": "MTVKVKFPKDIREYARKEKVKDSLIKLTETALAEAISKFHRRMIVLQGDTLNKAKLAGILAGGAARILSEYIPEMLERKLRDTEQIEVLYATDALGEDTYGRKRFEEFRKHFSLLAPTAELTSVTFKHSRDILGRTFDILVIDLSYDYSPNDLGRIIETVRGGGLIFVLTNPFEKWKDMWTGFHKSLVTPPYTIEDVKKRFNRRLIRKFTEHKGIYIVNTDRMSIERKPGKYRSQATLPEREKVEIPKNIRFPRELYELCLTRGQVEVLKTLEELIEKEGMVVLTADRGRGKSVSIGIASVGLAVSSKKKRFRIVVTAPEPENVQSLMKFAKKSLEVLGYKTKVITDNGLIKEVYAKGIGIRYYPPTKGYRQRAELYIVDEAAGIHVPILHRYLEKERVVFSSTIHGYEGAGRGFSVKFLKKAKEKREYKEVHLSTPIRYAEGDPIEKWLFDVLLLDAEPVELTEEDYELIRKMEVYLEEPDLDDWFENDREDLRHFVGIYVLAHYRNRPSDVALLADAPHHEARVLRLKNGKIVTAIQIAKEGGIPKAVIDKMAKGYKPPGNIIPDMMVKHHYAKEFARLKGYRVVRIATHPDAMDMGLGSKALELLIKEAEEKGLDWVGSGFGASPELIRFWVRNGFAVVHLSPTRNPVSGEYTAIVIKPISEKAKEIVKKANEEFRIRLTEWLGDTHRDLEPEIARWLFESPFGEAVNYPIYLTKTQKRRLEMFIKRILTYDTVVDAVKPLVKLYFLDGWMRPYLDERQIMLLIHRVLQAHDWKETAKLLNRTEMYTMVELRDIVRGLWYYYKHLIKDEEGEK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the N-acyltransferase activity,nucleotide binding,hydrolase activity,N-acyltransferase activity,RNA binding,tRNA binding,N-acyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:1990883",
                "GO-Name": "18S rRNA cytidine N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            },
            {
                "GO-ID": "GO:0004386",
                "GO-Name": " helicase activity "
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": " hydrolase activity "
            },
            {
                "GO-ID": "GO:0106162",
                "GO-Name": " mRNA N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0019843",
                "GO-Name": " rRNA binding "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            },
            {
                "GO-ID": "GO:0051392",
                "GO-Name": " tRNA N4-acetyltransferase activity "
            }
        ],
        "go_f_mapped": [
            238,
            61,
            19,
            238,
            96,
            138,
            238
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 489,
                "End": 646
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013562",
                "InterPro-Name": "TmcA_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 219
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 279,
                "End": 447
            },
            {
                "InterPro-ID": "IPR024914",
                "InterPro-Name": "tRNA_acetyltr_TmcA",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 805
            },
            {
                "InterPro-ID": "IPR007807",
                "InterPro-Name": "NAT10/TcmA_helicase",
                "InterPro-Type": "DOMAIN",
                "Beg": 283,
                "End": 457
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 469,
                "End": 664
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 223,
                "End": 396
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 489,
                "End": 646
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 498,
                "End": 610
            },
            {
                "InterPro-ID": "IPR032672",
                "InterPro-Name": "TmcA/NAT10/Kre33",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 609
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MRGPTPRPGGGALRAPGAARIAARAAAGRDAGGRPPPPAGGRRAAARRPAAGRPVTGTGDPLGCPAGRRAGPSGPPRGGAAGGAMRPGAPGPRRPGGAAARRPAGGRARAGGRAPGAGADDPGPAGGGPAGGGGPGPGPPPGDPAGGTRARGRPRGGRAGPPAAAAPPGAGRAGPSGPAPPPGRGGRGRRGGGGEGRGAGGPGPPPGRGPARSAGRPARGPGRPGPPGAPAAGHPGGTRPPPGGGRGAPPPPRAAAAGAGAPGPRRGAGPPGPSRRAAPGRGAPDRAAGAAAPPRARDPGPAARPRPAPAGAGAPPGHGAPGPGSPGRRAGGRAPARGG",
        "response#2": "MPPRGGPPGPGRAPGGAAGPAPDPRRAPGAPRGPRLARPPARPRGRPAGRPSAGPGPGAAGRRPPGAGRAPGGAGPDGAGAGAPGRPGSRPGAPGPGDRTARAPPPAAARARPAGGGRRRRPVTAPAAAAGPGPPARGGAGPPPGPPGRPGGRRAAMAPGRPRPAGPGPAARPAARPGRAGPARAGPAPARAAPRRAVGWADGAGRAAPGAPGAGRRGGPRRRGAGSAVRRRPGPGPRPPAGRAPAGAGPASAEPARAAHRDGRGVRCGTVLPPGVRPPARRAGPRAGPAAPGGLGGRGGPGPPPGRPGPAAPRAVREAPRGVRPPA",
        "response#3": "PPGPRGPSRGPAPGPGRGRRATPPARGARPRGAGRGRGRGRRAGPGRRRGPAPGDRPGAGPGAADPAGDPPGWGRWPWPGRPGAAGRAGAARGPAARRPAAGPGRGPAPPGNTRGPPADPAPGDPAAARPARGARGGAAPGGGPGGGRPGPGAGAAPGGARPAPRGRPAAPGAGAAGTAPAGAGAALAADPPPARAPPGAPGAGPAGRGAGPGPPGRRGRGAAPPGRRPRPGGRRARGTAPGRRAAGPPGPGRPPARSAPAGRPPARPGAAAGPGPAPGGAPAPGPARPAARPRGRGGPRGPGAPPGAARAARRPRGGRALGPPAGARARAAPGAGRGPPGPGAR"
    },
    {
        "reference": "MASSDLEAATALKVQGNKAFGQHEWPTAVDFYTQAIAKYDREPSFFSNRAQAHIKLEAYGFAIADATKALELDPAYTKAYWRRALANTAILNYKDALRDFKVVAKREPNNRDAKVKLADCEKLVRRMEFEKAIEVGDPPSAFEDLDIDAIAVDDSYDGVRLEKEMTQEFIDDMIERFKNGKKIHRKYAFQIVKAVKDIVYAEPTMVEIGVDQGTKLTVCGDTHGQFFDLLEIFRLNGYPSEKHAYLFNGDFVDRGSWSTEIALLLYAYKWLRPNGIFLNRGNHETDDMNKVYGFEGECKAKYNERMFKVFSESFSALPLATLIGNKYLVLHGGLFSDDNTSLDDIRKLDRHNQRQPGQQGLMMEMLWTDPQTEPGRGPSKRGVGLQFGPDVTKRFCEKNGLEAIIRSHEVRMEGYEVEHDGRCITVFSAPKYCDTTENKGAFINVGPELKLDFQVFEAVPHPDIKPMAYAQNSIMSMM",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Calcineurin-like_PHP_ApaH that are essential for its biological function; 2. The protein should be classified within Metallo-depent_PP-like, Metallo-depent_PP-like sharing conserved structural features; 3. The protein must be able to perform the cation binding,hydrolase activity,hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            },
            {
                "GO-ID": "GO:0016791",
                "GO-Name": " phosphatase activity "
            },
            {
                "GO-ID": "GO:0004722",
                "GO-Name": " protein serine/threonine phosphatase activity "
            }
        ],
        "go_f_mapped": [
            183,
            19,
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 133,
                "End": 478
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 215,
                "End": 411
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 148,
                "End": 471
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR051134",
                "InterPro-Name": "PPP_phosphatase",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 473
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 279,
                "End": 284
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 183,
                "End": 460
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 133,
                "End": 478
            },
            {
                "InterPro-ID": "IPR013235",
                "InterPro-Name": "PPP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 117,
                "End": 207
            },
            {
                "InterPro-ID": "IPR011990",
                "InterPro-Name": "TPR-like_helical_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 132
            },
            {
                "InterPro-ID": "IPR011990",
                "InterPro-Name": "TPR-like_helical_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 136
            },
            {
                "InterPro-ID": "IPR041753",
                "InterPro-Name": "PP5_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 156,
                "End": 471
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 215,
                "End": 242
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 422,
                "End": 438
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 312,
                "End": 338
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 400,
                "End": 420
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 278,
                "End": 302
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 344,
                "End": 371
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 245,
                "End": 272
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 215,
                "End": 411
            },
            {
                "InterPro-ID": "IPR019734",
                "InterPro-Name": "TPR_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 43,
                "End": 76
            },
            {
                "InterPro-ID": "IPR019734",
                "InterPro-Name": "TPR_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 77,
                "End": 110
            },
            {
                "InterPro-ID": "IPR019734",
                "InterPro-Name": "TPR_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 9,
                "End": 42
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 148,
                "End": 471
            }
        ],
        "ipr_mapped": [
            641,
            643
        ],
        "response#1": "MKISFLGQAVFKVETPKAVILIDPFITNPAFDTDLKPEEVKPDYILLTHAHFDHVGDTVELAKKTGATVIASYELAEYLREKGVKAIPHVGGVHEFDFGKVKAFPAFHSAEPVGFVIEVDGVTIYHAGDTGLFSDMKLISELYKVDVALLPIGDNFTMGPEDAALAVSWLKPKVVVPMHYNTFPVIKVDPYEFVRKVKELAPETEVKVLKPGESYEFKYKKS",
        "response#2": "MRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRSPCSPSSPESPPPRSPCSPSSPESPPPRSPCSPSSPDSPPPRSPCSPSSPDSPPPRSPCSPSSPKKKKKKKKKKKKKKKKKKKKRRRRRRRRRKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKEEDEDDEDEDDDDDDDEDDDEEDEDEDEEDEDEDEDEDEDEDEDEEDDEDEDEDEDEDEDEDDEDEDEEEEADDDEDDDEDEDDDDDDDDDDDDDDEDEEEEDDDEEEDDDEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE",
        "response#3": "MKKIKIGIISDLHNNINNINLLNKIINKENLDYIIFLGDFTDNFSLNFINNFIKIFKNKKIYFILGNHDYYKNNKKKIIKKRINLLKKIFKNIIFKKNFFIIKTKFGNILFSHGDLFSYNLDKNKYKKNIKINRKKLFNILKKNKINFLFLGHTHKNNIYKKNNINIINCGSWDFKNKKINNSYNLVIIKKNKIYQKKINYI"
    },
    {
        "reference": "MQSAGMHRATAEPIAIVGLSCKFAGEASTPDRLWEMLAAGRSAWSEIPPSRFNLKGAYHPSADRTNTVCFNSLCRGNPTEEKKVHVRGGHFLEQDLGLFDAQFFSFSAETAASMDPQIRLQLESVYEALENAGITLPDVAGSNTAVYAAVFSRDYRDGIIRDEDRLPRFLPTGTGDAMFSNRVSHFFDLRGPSITLDTGCSGGLVALHEGVKSLRTGESDMALISGEGLTDEGRFFSPDGKSYAFDSRANGYGRGEGIATIVIKRLSDAIIAGDPIRAIVRESGLNQDGKTETITTPSEEAQVALMRDCYRRAGLDYADTQYLEAHGTGTSTGDPIECRAIATVFKDSRSSEQPLRIGSVKTNVGHTEAASGLASLIKVVMALEKGKIPPSINFEKPNPKIALDEWNLRVVTTLEDWPAGPGGVRRASINNFGFGGTNAHLIVESQAAQPLPWQADGYGASATNLDSQIFVFSARDKQACVNMVNNLKKYLRQNAATDSPDFLLQRVAYTLGQRRTRFPWVTARPVPVQNGFREAIQALEVNMPVPRRTTGIPRIGMVFTGQGAQWYAMGRELIAAYPVFKASLKETDRHLAALGARWSVIEELNQDIPASRVHDVEYSTPLCVAVQISLVRLLRSWGVKPVAVTSHSSGEIAAAYAVGALGCQDAMAVAYHRALLATRSSLGSKQGAMLVVGMSLEETETYLARIDAQIGIATVACVNSPSSITVSGDQDAVNALEALARNDGIFTHRLKIHTAFHSHHMNPIADLYRSALQGALSPNHDKVESDITFSSPVTGRRITNLSQLSEPDHWVDSLLKPVQFVDAFTDMVLGASGASSANVDLILEVGPHTALGAPIKQILAEPKFAGLDISCLGSLVREVSAVRSMHSLAASLVAEGLPLDLDAVNFPHGRPPSVRALSDLPSYPWNHQTRHWYESRFNKGLRERAQPPHDLLGSLVLGTDPNSPTWRHILKLKDAPWLREHVVQEDILFPGAGFICLAIEAIKMLPELQSKAPQAAAGYRLRDVDLLQGLVIPDNDDGVEIQTSLSEVSDKEMGNRGWKRFEVSSVSADNQWSTHARGLITMEPEDAPDKTITKSRPADLSGYTRRFGPSDLYDMMRERGIYHGPAFQIITDIEQAGNNQRADSSLFIPDTAIPADSPYQTLIHPITLDAAFQTVYAPLLGGKEWDDAIVPRTLGSLWISNSISQAAGHRFKAFAILHHSDARTMRSDIYMADNNSDASPVLMVRNAVFQSVGRSAAPQQVKAQWESEPCTNVVWGPDMSLLSTPMRAQLKQQLSHPPEAEEARLLADLRRACLYFIYDALSSLRPFELRKLPSHHAKYHSWMQVQVSLAAECRLAEDSARWSSDTQEQRQSLIERVGRSSVNGEMVCKLGPHLAAIIRQEKMPLELMMENNMLNHYYQNALKCDRILSQAAHILQNLIHKNPRARILEIGAGTGSFTRYALPKIGTAATGGPLAELYHFTDISPAFFEAAREEFAAWDDIMVFEKLDIEQDPASQGYDMESYDIVVAVQVLHATTSMSKTMSHVRKLMKPGGHLLLVETTHDQLDTEFAFGLLPGWWLSEEPQRALSPSMSVPLWDETLKAAALSGVDFEVRDCESDEWYMMSVITSTAVPAHQLTLNPDSIVFVERKDAPCRQRWLEILRSNFAAAGQSPPVVEFETATAESYKGKWTVFLGEVDKPLLYDLDATGLKNIQTMIKHSRSLLWVTRGGAVKCERPELSLATGFLRSIRHEYAGRRFVTFDLDPHESLWSDTSTADIAKVMTTSFGSAADNAQTPPPYDFEYAVREGVILVPRLFRDSARNQAINPASVCWASPEALPTESFFQSNRTLALKVGVPGLLDTIAFDDDPAALADCTQLPPDLVEIKPRAYGVNFRDVLVAMGQLEERVMGVDCAGVITRVGCQAAAHGYAPGDNVFALVRSGYSSRPRVEWTNAMHIPQGLSFEQAASVPAIFTTVYLCFYKIARLQRGQTVLIHAGAGGVGQTAIQFARHIGAEVYTTVGSAEKRELLIQRYGIPADHIFSSRDASFADGILEATNGRGVDVVLNSLAGPLLQASLNILAPFGHFVEVGKRDIEQNSHLEMRPFSRHITFSSFDLLALSQHDKRSIHSSLIEIRRLLEEGAISPVYPVSTYPLGDIGKVFRLLQVGKHSGKVVLSISPDEQVRVVPQARTAKLRSDASYLLVGGAGGIGRSMAHWLAAHGAKNIIVLSRSAGTSPAVAELVAELQPLGCHVKPISCDASVKADLAAALSSCSAELPPIRGVIQAAMVLQDSVLERMTFEDWQTSLNPKVRASWNVHTQLRDADLDFFVFLSSMSGIYGYTTQSNYSAGNTYEDALAHWRVSQGLPAVSMDLGPVKSVGYVAGVAGVADRMTKLGHFPVTEEQVLRVLETAVLSPFDKQVAMGINQGPGSHWHPVGPSPLGRDARFRSLQYQKSTQRQATNGYSNASTSLASRLSDAKTRQQAEKLVVEAIASKLADIFMIPVAHVDAAKHLSEYGLDSLSAVELRNMLALQAAADVSIFSIMQSESLAALASEVTRKSTHVPASLSVM",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, Thiolase-like, Thiolase-like, SAM-dependent_MTases_sf, ACP-like_sf, ACP-like_sf, SAM-dependent_MTases_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the methyltransferase activity,oxidoreductase activity,phosphopantetheine binding,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004312",
                "GO-Name": "fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            20,
            4,
            24,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1959,
                "End": 2126
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2478,
                "End": 2557
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 473
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 444
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1402,
                "End": 1624
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2485,
                "End": 2554
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2469,
                "End": 2562
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1311,
                "End": 1620
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2487,
                "End": 2558
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2194,
                "End": 2424
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2513,
                "End": 2528
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2481,
                "End": 2558
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 12,
                "End": 269
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1959,
                "End": 2126
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2478,
                "End": 2557
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 473
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 949,
                "End": 1130
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 558,
                "End": 882
            },
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1999,
                "End": 2110
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 444
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 686,
                "End": 752
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 949,
                "End": 1258
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 2555
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1402,
                "End": 1624
            },
            {
                "InterPro-ID": "IPR002364",
                "InterPro-Name": "Quin_OxRdtase/zeta-crystal_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1988,
                "End": 2009
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 558,
                "End": 879
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 278,
                "End": 395
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1857,
                "End": 2174
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1094,
                "End": 1257
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 11,
                "End": 445
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 556,
                "End": 882
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2485,
                "End": 2554
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1874,
                "End": 1988
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1448,
                "End": 1555
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 397,
                "End": 498
            },
            {
                "InterPro-ID": "IPR056501",
                "InterPro-Name": "NAD-bd_HRPKS_sdrA",
                "InterPro-Type": "DOMAIN",
                "Beg": 1677,
                "End": 1815
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2469,
                "End": 2562
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1311,
                "End": 1620
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2487,
                "End": 2558
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2194,
                "End": 2424
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1879,
                "End": 1936
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 14,
                "End": 448
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 2197,
                "End": 2375
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2513,
                "End": 2528
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 935,
                "End": 1256
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 554,
                "End": 865
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2481,
                "End": 2558
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 949,
                "End": 1050
            }
        ],
        "ipr_mapped": [
            70,
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MVAVATSTLTVVPTCRSPPPSSPLSSPSSPLLWACHRTRGVTSLCRVLKRPRTPLPLRCAAQGSVRPEPTRLHRARSCGYMPAAPAPPPALRPTHPRRRGCEPDPRQDHQRQPPHPPGACRPPPPSSPVLRRRQRPRTPSPQRGAPHHQTALPRHRARPRARPRPAQPPPPRGRARRRGKTPLPGPRRTARSPPPLPPRALPADSPQGTARSPATRRRAGRSSGPSREPAEQQQQRAAKRELSRRRETRAGRQRQGATPQGAAREQGGEWVLDEPEEQAGAEPAARGAGRPRALPSARPRGAEERPRPPARLRALGRGPPRTAAAHAVLPRIHTHLRPPAARQQPRLHTQR",
        "response#2": "MGAGQHGRPAHTGRRADRSASRRHCGDPGDTATTPTDPADPTDRTDRTDPADPADLADLAGPAGPAGPAGLADHLRSSCHHPALPARRQCRHARHRDQGRQPRPPPPHHHHPRRTPRRPRTPRFPPRRPPPPPRRARALPGGSRPGGPAASRRRRRPRRDQHGRRPTPRWRVRAATAPAAQSAATPTLTDTTAPETFPPAPSRP",
        "response#3": "MPTPPTTPTPTTPTPPTPPTTPSTTTPSTPSHATTTHAKTTPSTTRATPATTPTWHTTARATTARAPARTRAQTRTPTTRRTRPRTPHTTRTTTAHRTRRARTRTAAHRTTRATPRSCTRARARAAARARAHPPRLRTRGSLRARARHNPRRTRATPATLQTPTPPATRRHTRAPRPRPPVRARPAAYAAPHAPRARPDRAARPARPPAQPDGPRPRPPRPAPRA"
    },
    {
        "reference": "MIEKSNNPFLSIDPIVERTKSNGEGLPLLSEKTKKGFDFTQIVVYLVGLSDGLTHLASLAIYYLFKDYFRLTPYQVSLILMYPYIPFILKPVIALITDSFSIFGMRRKPYLFLFSLFQSLNFLALAFLNLSVIQASLILFFISLCASFCTTVAEALVVESSMGQTYSQGTNKVTEFIASKAIGSLSVAYFSGYFLEKMPREYIFIATSIFPLIISLSCLFLKEKEYSTNRNIFNQLSDLIKFINTPIFLGPFLYIFVYMSGPDYDDAFFFFCTNKLGFRPSFMGTLRLTYGIASLIGIIIYRVFLKNCSLRKTLIITTLVSFPIYISPIILTEHINKFLGISNELFVLSGGFLIEAITEIQLLPLFILTANICQPGLEASVFATILSVKNLGSLTKKGTSSFITYLMKIDSYNFDNLSLYILTCGFFLLFSLTLVPLLPNEEHIEKLKNKETSKG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within MFS_trans_sf, MFS_trans_sf sharing conserved structural features; 2. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008517",
                "GO-Name": "folic acid transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 42,
                "End": 231
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 50,
                "End": 443
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 42,
                "End": 231
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 50,
                "End": 443
            },
            {
                "InterPro-ID": "IPR039309",
                "InterPro-Name": "BT1",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 453
            },
            {
                "InterPro-ID": "IPR039309",
                "InterPro-Name": "BT1",
                "InterPro-Type": "FAMILY",
                "Beg": 44,
                "End": 445
            }
        ],
        "ipr_mapped": [
            34
        ],
        "response#1": "MGLTATGSVQLWHVYVLAFLNGTVSAFDVPVRQSFVVQMVGRADLPNAVALNSASFNGARIVGPAVAGVLIATVGEGWAFFVNGASFVAVIAALLLLRPHELRPAPRERNALREGLRYVWSRRELRSILLTIGVFSLFGLPYAALMPVFAQDILHVGAAGYGLLSSAVGVGALTGALTLAGRGGVRRRGRVMLAAVATFGAALLAFSQSRVFWLSCALLLPVGFAALVFMASANTLLQTLTPDAMRGRVMAVYMMVFQGMTPFGALLAGTMADRFGAPTAVAVGGAACLAFVAAAALAPPLRRLDAPD",
        "response#2": "ARRGTAVGVWAGVSGLATAAGPLIGGALTEHLSWGWIFYVNLPIGVVAVLAALVFVPESRDPGAVRRPDLAGAVLVTVGLVGLVYALIEGQHHGLRVAAGLTGGAVLLAAFVAVELRARSPMLPLRLFANRNVSGANAASFLIYGAMYGFLFFTTLYLQNVHGYSAFRSGLAFLPMTGMLMVMAPVAGRLLTRLGPRTPMLAGCALYTGGLLWFALTVGPDGPYLTGVLPGFLLTGAGLGLAVPAVTAAAVSGVPRREAGVASAVVNTSRQVGGALGVAVLATIAARSGTDPAALTAGYHTALWCGAALAAAAFVAVALLVRPARPEAAAA",
        "response#3": "MTTADTTPDTTPDTTPDRSPDRSPDRSPDRSRDRTRRPDRTRDRAVGAVLVTAGLAVLVAVGVAVTDADGATGTTVVVPAAVLVAGAAAGTVALRAPGHRRRRVALGVATGVAVVLLVATVVVVGGLGTAPAAPAWVLVVAVAAVPVGALLGVLAVRSPDRRRRGGGVVLVAGGAGALAGTVVVGVLEPSHDTTAGPGTSTATAVVVGALLVAVLVAACAGVAVAVVGVRRHRAARRPDG"
    },
    {
        "reference": "MVNFTHVSEFVLLGFQGGPGMQAMLFLIFLILYGIAVVGNLGMIVIIWVDAHLHTPMYAFLQSLSLLDICYSSTIAPRALANSMQEDHTISFGGCAAQFFFLSLFGITEAFLLAAMAYDRFIAICNPLLYSVSMSHQVCVLLISGSYLWGVVNAIAQTTMTFRLPFCGSNEINDFFCDVPPLLSLSCSDTFINQLVLLGLCGSIIVSTFLIVLVSYIYIISTILRIPTMQGCQKAFSTCASHLTGVCLFFGTVFFMYAQPSAIFFMEQSKIVSIFYTMVIPMLNPLIYSLRNKEVKQALRRSMQKLSL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, Olfact_rcpt, GPCR_Rhodpsn that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity,olfactory receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            },
            {
                "GO-ID": "GO:0004984",
                "GO-Name": "olfactory receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            },
            {
                "GO-ID": "GO:0004984",
                "GO-Name": " olfactory receptor activity "
            }
        ],
        "go_f_mapped": [
            0,
            1
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 234,
                "End": 243
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 101
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 127,
                "End": 139
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 281,
                "End": 292
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 190
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 288
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 24,
                "End": 48
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 270,
                "End": 296
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 57,
                "End": 78
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 102,
                "End": 124
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 29,
                "End": 303
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 108,
                "End": 124
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 234,
                "End": 243
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 101
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 127,
                "End": 139
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 281,
                "End": 292
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 190
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 288
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 24,
                "End": 48
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 270,
                "End": 296
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 57,
                "End": 78
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 102,
                "End": 124
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 29,
                "End": 303
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 108,
                "End": 124
            }
        ],
        "ipr_mapped": [
            0,
            1,
            2
        ],
        "response#1": "MLSFSDFCYSSVTVPKMLVNFQSERKTISYAGCMTQLYFFLFFGSLDCFLLAAMAYDRYVAICNPLLYTTIMSTRVCVLLIGASWGASFVVSTLVTMVYTSMAIFLVPFSCIVISYTFIISTILKIRSTEGRHKAFSTCASHLTVVTLFYGTITFIYVRPKSSYSTDQDKVVSVFYTVVTPMLNPFIYSLRNKDLKGALKRLLGRKTF",
        "response#2": "MKPGNHTAVTEFILLGLSDRPELQRILFGLFLSIYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFVDICYSSVTVPKMLVNIQSERNTISYGGCATQLYFFLAFGDTECFLLAVMAYDRYVAICNPLLYTVAMSPQVCALLVSASYVGGSLNALLHTCLTFSLSFCGSNKINHFFCDIPPLLKLSCSSTHVNELVIFIFGGSITMVTVLVILISYTYIISTILKIRSTEGRHKAFSTCASHLTVVTLFYGTIIFTYVQPKSNYTTDQDKMVSVFYTVVTPMLNPFIYSLRNNDVKGALKKQLGRKIF",
        "response#3": "MAPGNHTAVTEFILLGLSDDPELQQILFGLFLSMYLVTVLGNLLIILAISSDSHLHTPMYFFLSNLSFVDICYSSVTTPKMLVNFQSERKTISYAGCMTQLYFFLFLGDLECFLLAVMAYDRYVAICNPLLYSTKMSTQVCVLLVVGSYVGSSFHALIHTLCTTRLSFCGSNKINHFFCDISPLLKLSCSSTHVNEMVISFSAGSITMVTVLVILISYSYIVSTILKIRSTEGRHKAFSTCASHLTVVTIFYGTIIFTYVLPKSSYSTDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRLLGRKSTKAFSTCASHLTVVTIFYGTIIFTYVLPKSSYSTDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRLLGRKSTWKLFTCKTVSFIF"
    },
    {
        "reference": "MDNISNHAFNYPVLVLNKGLLPEHDDIALARYLFSALALAVSRITQNEEMIVGFHLHPQEITRWKDDECIRQYILPLNIRFNSATPIAGFIREIMTWMTPDAIHQKNAMGASVLTLGPQHALHDIFDLEISWQPPVESEPVQALTCHVASREDALVLTLRFNPARFSATQMQKLPEVWRQITASAAKNGAETLRDIGLIDDAERQRVLHAFNQTEQAWDGETTVAARLKNRAQRHPEQTAVVFRDETLSYRQLYQQAGALAHYLNALETERERCVGLFVEPSLTLMTGVWGILLSGNAYLPLSPEYPEDRLAYMLENSQTRIIVTQPHLRERLLALAPPGIQVVTSDDVDAFMRQHAHSLPDAPQNDIAPHHLAYVIYTSGSTGKPKGVMIEHHSVLNQMNWLAQTVGLNQETVILQKTPMSFDAAQWEILSPACGCRVVMGEPGVYRNPEQLVDMLAEYRVTTLQCVPTLLQALLDTERLTHCPALRQIFSGGEALQKHLAQACLETLPDCELINLYGPTECTINNSAFRVDPVSVRQGPDTLSIGAPVANTRYYILDNCLTPVAVGQIGELYIGGDGVARGYLNRDDLTAERFIVDPFAPAGSGRRLYQTGDIASWNPDGTVQYAGRADNQVKLRGYRVELDEIRSAIETHEWVKAAAVIVRNDPFTGYQNLISFIELNAREAALMDQGNHGSHHQSKADKAQVMLQLANKGCREFPAASQPYTLDLPGKQPDEKQRLTAFSRKTYRFYDGGAVSREDILSLLHEPLLTAISRQPDALTLDELGHWLRYLGQFTSAERLLPKYTYASPGALYATQVFLELNGVAGLTAGHYYYQPVHHQLVRVSEQAAVTPGSLRLHFVGKKSAIEPIYKNNIREVLQMEMGHIIGMLDIILPDYGLGVALCDAAALDPTPLAIDLDDDYLGACDVLSGPRLPTDDDLDIYVQTAGANIADLPVGTYRYVRGDLQHIADDVIDKKHVIAINQAVYERSSFGISVASRTEGWAGYVHVGRKLQRLQMNPLNIGLMSSGYSSETGNDLPAARRFWQILGHRTGPYYFFIGGRISDEQKYSEGMREDAVHMKGPAEMIRDDLAAFMPDYMMPNKVLILDEMPLTANGKIDMKALANINVELKHKTIVAPRNPLEHQVMAIWQAKLKREEMSVDDNFFESGGNSLIAVSLINELNATLNASLPLQVLFQAPTVEKLAAWLSRARREPVSRLVQLQPKGRQAPIYCWPGLGGYCMNLRLLARQLGAERPFFGIQAHGINPDETPYATIGEMAARDIELIRQHQPHGPYTLWGYSFGARVAFETAWQLELAGEVVENLYLLAPGSPKLRDERVAAMNRKADFDNPGYLTILFSVFIGSITDPELERCLETVRDEESFVAFITGLNPALDDGLVRRITRIVAQTFEFTYTFSELQQRQLNAPVTIIKAQGDDYSFIENHGGFSAQPPTVLELMADHYSMLKAPGIDELTSVIQYQQSPPSLVG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, AB_hydrolase_fold, AB_hydrolase_fold, ACP-like_sf sharing conserved structural features; 3. The protein must be able to perform the lyase activity,oxidoreductase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            32,
            4,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1145,
                "End": 1208
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1137,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1133,
                "End": 1214
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1211,
                "End": 1477
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1218,
                "End": 1481
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1144,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1136,
                "End": 1208
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001031",
                "InterPro-Name": "Thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 1230,
                "End": 1346
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1145,
                "End": 1208
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1137,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1133,
                "End": 1214
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1211,
                "End": 1477
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 229,
                "End": 585
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1061,
                "End": 1132
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 630,
                "End": 724
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1218,
                "End": 1481
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 249,
                "End": 661
            },
            {
                "InterPro-ID": "IPR000415",
                "InterPro-Name": "Nitroreductase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 745,
                "End": 930
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1144,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1136,
                "End": 1208
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 376,
                "End": 387
            }
        ],
        "ipr_mapped": [
            45,
            35,
            29,
            30
        ],
        "response#1": "KNFSDSKNKNFSNFPDSKKNFPNFPKKKISPNFSDSKNNFPNFPKKKNFSKNFSDSKNFPNSDSKNNFPNFPKKKFPNFSPKKNFSNSDSKKNFPNFPKNFSKKNFPNFSDSKNFSNFSKFPKKKFSKNFSKNFSKNFSKNFSKKNFPNFPDSKNSPNFPKNSPVKNFSKNFPKKNFSKNFSKKNFPNFPDSKNFPNFPKKKNSPNF",
        "response#2": "MFKTGSALYREGAPFLPLVFFVFVPASEYAAAPVRAPVSAPDRPPDPRCGAGPLRAAGAGSGGPPARGPAVRRPAGPAPGPAGPPARPRAVRRRRPVPRRRGAPGARPAGPAAHGRPPAGRRAAGPARRRRCRRRRRRRPADRGAGRAGRAREPAGRRRRRAGKAARPAGPAGEPAGAGAAGRAGGAGAGRAGPGSGRGARGAARGPGGRAGGGAAAGGRAGGAGRPGGRAARRQPARPGGAAAGRAVPPGPARGPAPRPARPGPRPAAAGPGPAGPGPAGPAGPRPAGSGPRRATDRPAAPAPAARPRPARPGPRPAGPPPPRPPGPHPRPRPRPCPRRTTAPGHP",
        "response#3": "MGGEGGAEGGAGGGEVREGGEAEGGAEGREEGWEEGRGEGAGAGGGGGGGGGGAVGGQRGGGVRPGRGEGGRGAGGAGAAGAGAAGAAGAAGAGAGAAAAGGAGGGDGARRADGPRADGPRADPARADRSRTDGSRTDGPRTDGRRADGRRAGGRRADGRRAGPHGAGRRRGDRRRAGRRRAGPLRGRRRPGGPRPRPGPRPDPRRRAAPRPRPARRPPPGGRAPRRTPRGRCAPPPPRPPPAPGPPPRHPAAPPPPARPPPARPAPPRSPPARPPPARTPPARPPPAPPPPPAPRRPDRERVPRRRRPPRPPRPPPRPPRPRRPRRGRPP"
    },
    {
        "reference": "MTTTSASTTDHLIDQQVIDGQAGYTKSFLNIYDLAVFKGTAPLAWHCSPAVSRQMYDTCLGANHVEIGVGTGYLLDNATFPVADPKITLVDLNPNSLAHTAQRLNRYDVTTVRANVLEPLPLEERAYDSVGMSYLLHCVPGSIKEKGIALKHAAAVVRPGGVVFGATVLSSGVPVSARGRWTMNYLNKRGDFHNQEDNYDDLRDQLAQYFPRFQLTSRGCVGIWRAWTTD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 211
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 61,
                "End": 207
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 211
            },
            {
                "InterPro-ID": "IPR016584",
                "InterPro-Name": "MeTrfase_VrtF",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 230
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 65,
                "End": 163
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 61,
                "End": 207
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MSTDWDEVAAKYDDRRAAEEPHPGEMLLLDALGPVAGLDVLDVGCGTGRIANALARAGARRVTGVDLSAGMLARGRERAAAEGVAVEYREGDVTALPFEDGAFDVVTCIYVIPYVDDPARAFREIFRVLRPGGRAVVSVWADADDPARREAARVTMETASGPIEMTARWFSRDELTGYLREAGFTDVTTREVRPPTPEEQAKIRAEIERAVPPRVLVTATRPE",
        "response#2": "MSSTGVAAARAAATRAAKGLIDDPFAEPLVRAVGVDFFTRLASGELDLDEIDVGAPRMQRIADGMAIRTRFFDDFFLDATAAGIRQAVILASGLDSRAYRLPWPAGTVVYEIDQPQVIEFKTTTLAGLGAQPTADRRTVPVDLRDQDWPTALRAAGFDPAQPTAWIAEGLLIYLPPEAQDRLLDNITALSAPGSRFATEAMPDINADKEQMAARMRRMAANWRRHGFDLDAAALVYHGERNDVAAYLAGHGWGATATTVNELFAGHGLPPIDDDDNELFGELQYVSAELTGTGRR",
        "response#3": "MPRRRQPPRPPPRPRPRPRPRRRPRRRLRPRRPRPRPPRRRPPRRRRRPRPRPRPRPRRRPRRRPRPRPPPRPSPRPRRRRPPRRPRPRPRPRRRRPRPRPPRRPRPRPRRRPRPRRRPRRRAVNDETKQLVRDGFNRIAATYDATSVHSSGPSLRRLVDLAGDLTGLDILDAGCGTGVVTCFLAERVTEGHATGVDLSPGMLEVARQKAAEQGLTNVTFAEGDIEALPYPDATFDVVTCREVIIHVPDKPMAFAEMFRVLKPGGRLVTSTVSLGETVPPTELMRRRFAEKGIEFDIPFFNAVTPAEYEQWLRDAGFTDVTTETEPEHFYLTEEQLEQRLGPLDELCAELGIDPAEFRKHVPPRTVVTARKPGQAA"
    },
    {
        "reference": "MSLKGGTAAPAPMAPPRKWYDMTSAEFYVYVVAFMCGISIMMPINAVFSAPSYMLEYYLYATKDPFLVPKMTNFWTNVMTYYNLISMVTSLVVEPLTLLKSFRKIPMLVRLLGGLSVLIIEIIVLMVVPARGTTEAGAVATMCIAGFIGGLGTSIFESTVYGMFGAFPPSFTSIMMGGVGISGVLTSLIQIIVKAALPDTYEGVKKQSYIYYSLDVGIQAATFIALIMMRFNSFAQLHFGDLGGVKSKVDAGSLAGAGENVREPGAEATELEQYTEPAIGQIQEKNAEAHKDDPLAERELSEEESGDSRAVEAAGEAPTSNEILRATSVFSVLRSVKWMFVACGFNFLITLFLFPGIATGMFPESKWFATVAVFIFNCCDVLGRFSSAFRITWPRRYNQRWIIVAASFARVIFVPLLLLHSYHYIPSEAYGYVMQVVFGLSSGYIASMALVLGPQSKGIDNDGKRFVAGTLMGISILVGGTIGTVLSIMTQTIRETY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within MFS_trans_sf sharing conserved structural features; 2. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005337",
                "GO-Name": "nucleoside transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 327,
                "End": 490
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 149,
                "End": 171
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 468,
                "End": 492
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 177,
                "End": 197
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 327,
                "End": 490
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 25,
                "End": 492
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 150,
                "End": 489
            },
            {
                "InterPro-ID": "IPR034764",
                "InterPro-Name": "ENT1/ENT2",
                "InterPro-Type": "FAMILY",
                "Beg": 33,
                "End": 495
            }
        ],
        "ipr_mapped": [
            34
        ],
        "response#1": "HLTKYHYKILGLVGLGTFFDAFDLLSISFAMPSIAKEFQLTPAQEGSLASVGLVGMMFGAMFFGTLSDKIGRVKVFNYTLLLFAFFSLLCGFSVNYTMMLIFRFLQGLGVGGDVPVAWALISEFTPKEKRGRFVLSYEIIFTLAIPFAGLLGYVLIPLLGDSTFLAFGFSNWRIMFFIAAVPAIVAFFVRKNIPESPRFLVSKGKNKEALEILKQIEEEVKKETGQELTLPEVKEEKEKGNILELLKNKKLLFTW",
        "response#2": "MTTTPTTPTATTPAPRSRTTRRAAAAVLVVLGVVLELAGVGVLAALLVTDGTDGDAATGALVLLGVVAVGLVVVGPLVVAAGRRADVVPPRVDALPEARRRRVRQVRAAALVAGALTTGSTALGLWLVAGSRDADRDVLAATAGLLLLVVGLGVLVAALTVLALHRPVTTPATRAELELARRDRVARARRLAVVGAVVLAVLAVAALAAVAVAAVVGDSWRSPWWGVGFWAGVALLVVGALVAVAVPVVVRRADGVVDDAVDDRARVAAARRRATVSSAVGAGVLVATAGQAVLAAVGSSSSGTSCSSTETGATLCVDAGTDWALVPLVTVSTAVVVLVVVVVVSVVVALVRRPARPAA",
        "response#3": "MEAGMQAARVAGPPLGGALYAVAAAVPFAADAVSFAVSAALLWRLRAAPAPRRGRWREIGEGVRWLWRHPVLRTIAACTGLANFFSNAYNAVFVLFCVRELGFGPAGYGVLLAAMGVGAVAGALLAGPVTRRLRRPGLALVTVVAVEGAATLGLALVRSPLAAGAVLAVMGVASVVYNVVNVTYRQTVTPDALLGRMNSAMRFVVWGTMPLGALAGGALASALGVRPAVAVGGAGVLAAGAWVAVSPALRRLEPPERSETSERPEISERPERPAARA"
    },
    {
        "reference": "MIPGSNPGGRIHNVIEMFENYFMDAVKGYYRHLAIIESQDPLEKINSLIDDYLKVNKKPRVIYGFHPWLDNSKDRMKELKKRFENFLDIDYSNSEKYLGQSADLVILDAMDDFRPNYIARFVDMTKGGGIAIIYSDNILEGKLYKKSLTRYGVVKDLFEARFIELAKRYRGIIFFQGNDRITFTPYSSNETHKPYKKIPKSPKVSMELHELCLSSDQNKVLEESLFIMNLGKRVLVITAARGRGKSASIGLFLSYLMSEGNFGSIIVTSPTYYSSQEIFKFIIRGLEALNVKYKVITSRDGKIMKISTRDSRVKWVSPDLAKNEEGDLIVIDEAAAMGIEFLDYIVRSWDKVILVTTIHGYEGSGKAFLKYVDKLKGKVLLKNIKMDYPIRYAKGDPIEKFLFDVFLLDAEPHEVEYNGKLKIVEVPQEELFRDDDLLKSVYGILVTAHYRNSPDDLMLLGDMAFQKVIVGYSSENPVAVCQVVYEGGLTDKQIWDISNGLKNEGHLIPHRLIKYMRALDFGKLKGWRIMRIAVSPENQGKGIGSRVIEEVIKMAKGVDWIGSSFVADYSVLRFWIKNGFLPVYLSSIKNEELNGYSVIVIKALSERTKEFVVKLSSLLKDKLLRTSHQVYYNLNPQLIVLLLRNTYSERIEGEVPDLYVDKIKAYTEGKVPYNVIAEAAHFLVTKHFLELKADLSIEAEASLVARVLQGKSWYHAGLMLGLSSREVEDNVKQSLGVLLETYT",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the N-acyltransferase activity,nucleotide binding,N-acyltransferase activity,RNA binding,tRNA binding,N-acyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:1990883",
                "GO-Name": "18S rRNA cytidine N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            },
            {
                "GO-ID": "GO:0106162",
                "GO-Name": " mRNA N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0019843",
                "GO-Name": " rRNA binding "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            },
            {
                "GO-ID": "GO:0051392",
                "GO-Name": " tRNA N4-acetyltransferase activity "
            }
        ],
        "go_f_mapped": [
            238,
            61,
            238,
            96,
            138,
            238
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 465,
                "End": 583
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 357
            },
            {
                "InterPro-ID": "IPR032672",
                "InterPro-Name": "TmcA/NAT10/Kre33",
                "InterPro-Type": "FAMILY",
                "Beg": 555,
                "End": 740
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 442,
                "End": 556
            },
            {
                "InterPro-ID": "IPR007807",
                "InterPro-Name": "NAT10/TcmA_helicase",
                "InterPro-Type": "DOMAIN",
                "Beg": 236,
                "End": 409
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 465,
                "End": 583
            },
            {
                "InterPro-ID": "IPR013562",
                "InterPro-Name": "TmcA_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 17,
                "End": 175
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 421,
                "End": 605
            },
            {
                "InterPro-ID": "IPR024914",
                "InterPro-Name": "tRNA_acetyltr_TmcA",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 742
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 232,
                "End": 399
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MGEAGGGGEEEEGGGEEGGGEGAPGAEGRERAEGAVGELVAGGEGEGRVERSGEEELAGAERERAGEEVDTDRVLRALAGEAEAHGRAGRAVRALEAEAAEEEREALAERARAEERFDECLLESREEGARERGAGARAEGVARAGARDAVEEARELGASRMRAFAEEAARGSVGSGRREGEREAALRRAAEQVEEAAERSGGGVRRERAAERAEEAVPRRRERLLGMEREVEERAERERLAREALRARAPREGGGEGGG",
        "response#2": "MPGSVEPLLEVGGAASGAPRAVRRRDGERAVRELLAEVLREAGARRGAEARRLEGRELLEALRRALEEALERGVRERRPAEEAPRERRQARRALERHVLGEVALADEAREAEERLAEELERELAQRLVRRARWRELRRLGLEERDREADRRALGAEARLAARAQERLRELLEALAAAGARGEGEVARDERRLEGRRAASLRRELEERARELALAALEGPEDEEGALEAPEALAAGERARALLDELRAALELEAELEARRAAVLLEGQLRLAEEEARERARARLERALARLLERVAEREAGEEVARERAAERAAGRGDAAQAEVRRDALLELEERLAQLRG",
        "response#3": "MGPGPPPGRPVPVGAAGRGAGGAPRPRRRPPLPPPAARGRPARAAGGGARPARAGPAGGPEPARPRAAPGRAPAGAGPGPRPGGGRPPTGREVGGPVPGPRPGGGGRPGSGGATGPAGPGARPRPRGAGPRGGRGRPAARRPRRPGRAPPAATPGPLPPAPARPAPAPEPPGRGPRVPAGAPGPGARGAAAGPAPPGGAPARGAAGAGPPAPGPAEPGGPPPLGPSGRVSGPVPAPTRARAARRAAAAPGRGRAHGREPRGPGRGRGRGGADRGPAGVAGCLAGAGPAGTRPAAGGGSDPVPAGPARRAPPGRRRGGRPDPGLAAPPAAGPAAGPADALGRPARRRRPGARPGPEAAPGAGAGRAAARGGGARARGR"
    },
    {
        "reference": "MEDDDFSIKDKKENYETCSTETISSYISINEKCQLIEKDINDDNHENPYMIFNKISSSLIAMLQGVEVLCNLSIIYLLKDNYHLHPASLSIVMCFIKIPWSIKLVWAVISDNYPIFGYRRKYYLLLGSFLCILSLICLGLITHNNLFITILLLFIYFFGSSLCNVIGEAQVVESNRNCSINSSARNVSLFFAFRKLSFAIMSYLSGYLLLLISKKHIFLIGSFLPICVFTSGFFIIEKRNYTKSSIKDQIKCIYSIIKLSYLKNFIIFIFIMMSTPSCGNTLFFYITNELKFSPNLLGKMAMFQSLASFISIISYMLFFTKIDIRKLLLYSTIIITPFCLLPLVVIKKVNYFLFIPNTLFFITDTVLIEFIAEFQTMPILVLCSRLIPEGFESTIYSLLLSSNNFASIISSFLSSLLTYSLNITSTNFTNLPYMIIICCLTNIIPIFFLYILPNHSQKKNLQHSNSHTQKYYSYPSTDYISSQKSDSSEITKFSADMQIDDITLE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within MFS_trans_sf, MFS_trans_sf, MFS_trans_sf sharing conserved structural features; 2. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008517",
                "GO-Name": "folic acid transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 55,
                "End": 248
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 261,
                "End": 466
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 56,
                "End": 459
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 55,
                "End": 248
            },
            {
                "InterPro-ID": "IPR039309",
                "InterPro-Name": "BT1",
                "InterPro-Type": "FAMILY",
                "Beg": 58,
                "End": 465
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 261,
                "End": 466
            },
            {
                "InterPro-ID": "IPR039309",
                "InterPro-Name": "BT1",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 466
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 56,
                "End": 459
            }
        ],
        "ipr_mapped": [
            34
        ],
        "response#1": "MTGPATEPATEPVTEPVGEPATEPATEPPSRRDRRRTAVRVGGSAAALAAVSAVVVAVGPDPDFFTGRRWWLLVPLAAVAVVGWVGGVRGRTDRTGDRTDVRTDRGDRRDHRYRRAERLALLLAVALLVAAGVQLVLAWVVDRLTTTVTGPGDDAAVNALFLAAGGLALLNFAAVTAAVLRPSPRPAPDAADRTRRRRDRWLLAPAVLAAAVAVTGVVGTRPWPVGLVPAAVVLAVVVVVLAVDALRPGPRRGRRVLTGLAAAAVALVVVAGLVPGLAPAALTVVALGGCAVLVVAARRAVGAETTGTEPDAEPDAEPEPEPEPDAEPD",
        "response#2": "MTDRRDGAAPAWGAVLALALSVFVFVTSEMLPASLLTPVADGLAVTEGTAGQAVTVSGLVAVLAAVPLSRATAGRDRRTVLLAFTALLVGGGVLVALAPSYAVLLAGQVLLGAAVGGFWSMSTGVAMRLVPPSAAGRAMAVVNAGTPVATVAGVPLGTLLGEAVGWRWAFAAMAVLGVAVFAWQWRALPASPPRARAVSWRRPGVVVAVAVTAMVVTGQFAAYTYLAPLLRDVAGVPETLVPVMLAVFGVAGVAGGVVAGRLADRTDPGTVLTATAGALTVALLALPPAASVGTAAALVTVALWGLVFGGIGVVAQTRIMRAAPEAADTAGAANVAAFNLGNAVGAALGGAVVTTAGAGATPWVGAGFAAAAVVAAVAERVVVARRRAVTTTT",
        "response#3": "MGALAVPIRTDLGVSDTLLGLAASAFFLASAVAAAPWGRLVDRTGRRRPVLVVSNVLAAAGLLVVAAAPSFAVLLVGLVVAGLANAPAQPGSNAVLAGATPPERRGLVFGVKQSSVPAGTVAAGAVVPALALTVGWRWAFAVAAAVCVGTAVVALRVRDPPAKATAGTRTAPATRGPLRDRSLVLLVVAGTAGTLAANSVGAFLVLSAVDRGFGAAAAGLALAVANGASTVARVATGWLADRLGARRVLVPSMVVSALGFLLLALTQSTAGLLAAAVCTGLAAGAWNGVYTLAVVRLAGPERAGTALGMFQTGGFIAGMVAPPVFGAVVDAGGYGLAWLVSAAVCALSAPLVARLPGRPASA"
    },
    {
        "reference": "MVNKEQFYDQIRKALEDGNTRYYRNLIYIERDDYFDHVKEIISLFLNFKSNPSVAYGFVPWASGSKERMRTIKEYFSKFDDIDYANAEYYLGNTYDLVILDTVDNFQPINIGRLVDLARGGGLIIIYTNNLIKDKTFRTSIMRNGLILDEYEKRFKRKLYEHEGIFIIDVNEYIPKPFSGNTMPKAEKKVPRNPLMPKEIHELSLSEDQNRVIESFTYLLSGGQRALVLTAARGRGKSAATGLSIAGLIEKLRERKEKSIRIIVTAPSIASASQVMSFAKLGLEALGEELSVKVSDTGHIKSLRGDYFKLEYVPPDAAIEDEGELLIIDEAAALGINYIDLALRAWKKVALVTTVHGYEGSNKAFLRYLRRLIESKRIRVKWVNMEQPLRYAKGDPIEKWLYDALLLDAEPSEPQYLNDTMIYEDVDKSELANDDNRLRAIYGIMVTAHYKNNPDDLMIMLDGIHHKIKAIRIGENSYIAACQIAEEGELSDNMVDIALKGGTFDGDLIPDRIIKHVRIKDFAKLRGWRIVRIAVAPELQDKGFGSELLKMIYEEARDKGVDWVGSSFMSDQKVLNFWIKNGFIPVHISPKKNEKLGDYPVVVIRPISDIATKIVKISAYMLKEKLLNTLHDVYFNMNPEVVRLMLTSTKIVSKTINVSPIILDKTISFLQGVSPYESSADGIHMLTLKYFWDGERDWSLTQDEELVLIAKVLQGKPWSYVSTVLSSNRTHIYELIYSAISKLMKKYYNLTADSKVGLTLKDVMNSQQYD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the N-acyltransferase activity,nucleotide binding,N-acyltransferase activity,RNA binding,tRNA binding,N-acyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:1990883",
                "GO-Name": "18S rRNA cytidine N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            },
            {
                "GO-ID": "GO:0106162",
                "GO-Name": " mRNA N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0019843",
                "GO-Name": " rRNA binding "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            },
            {
                "GO-ID": "GO:0051392",
                "GO-Name": " tRNA N4-acetyltransferase activity "
            }
        ],
        "go_f_mapped": [
            238,
            61,
            238,
            96,
            138,
            238
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 511,
                "End": 591
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 225,
                "End": 398
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 511,
                "End": 591
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 154,
                "End": 391
            },
            {
                "InterPro-ID": "IPR013562",
                "InterPro-Name": "TmcA_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 169
            },
            {
                "InterPro-ID": "IPR024914",
                "InterPro-Name": "tRNA_acetyltr_TmcA",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 747
            },
            {
                "InterPro-ID": "IPR032672",
                "InterPro-Name": "TmcA/NAT10/Kre33",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 552
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 458,
                "End": 608
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 555,
                "End": 607
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 441,
                "End": 553
            },
            {
                "InterPro-ID": "IPR007807",
                "InterPro-Name": "NAT10/TcmA_helicase",
                "InterPro-Type": "DOMAIN",
                "Beg": 228,
                "End": 408
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MRGGDGPWGQGRGELEEAREGEVALEADEEALRERGEDGRGAEERRAEGEERRRERAREREAAREALDEEREAAREAEEGARRYRAGEEARRGEAEGEAETELLALLREAEGRYGPEGLVVGPGERAAAEAEPGVRVLARTLAEQAEAGGDLLERALEALEEGARERGVCEAEAEALERRAERRELERRLERELQRLLARAEAEPDRARRARGEALARVLELDALAEEVEPVRRAALAGRARREALEEVGRAAELGDLERLRLEPEEELARPEDPEALEAARRAERRRAAEAAEGRWGPEREAEEAEREAQRRARAEGRRGPERGPLERRDRARRLLEACREAGEEQEREGPRP",
        "response#2": "MRGPGRPPDPRPAGGRPAATGGGPPPPAAPPGPGGPAAAGAGGREAAEALAPRPGPGRDPEGLRAARSASRRAGRGGADGAVRPPPRPGEGGARRRAERLRARVGAPGPGAGRPGARDRPSGPGPARGGPPPRGRPPRRPAPPERARPAPGAGGRPRRSGVGPLRPGPDAPARRALADCVEAPERAAAEEAARAVDERLGSGAARAASLAPGARPPDRAAGAGWAEPAGEGGCASWPTGRRARGAAPRGARPRGRAPAAPPVAPGRPPPPPPAPLGPARPGPGARRVPRPPPPAPRARRGFGRGTRRADRP",
        "response#3": "MAEGGHRAEDERELEARGEAAAERRGEERARRGARDARGAPGAGEGERVWAAEGERLPECLRVGAQAREDREREELEERLRRRLRRVARQRGASGAERVRALRELEAERRLEDEGDEALRLGVRREREEARASAERSLARGRRSGRAVREAGREREEELEAAELRRAEAARARSEGEAPALKEAVREVRRTEEEVEAERAAAEEARRREREFELRAERAEEDAARRAREAEVRAYWGRAEREAGAEEVELARGARRPAEQDERLEALCRELGERRPAGVRPFEDAAEALAEARGDG"
    },
    {
        "reference": "MSSASTPTAPYLEDLVRNSLDQNLPWVVQKYGGTSVGKSLDNITKIVGSYIDNGSKVAIVCSARSTQTKSLGTTNLLLQASREALQPAMSSSGDGRSGSMSGTATPFYPKRVGSGFFGKDQSTSMTSSVSSLSQLESQLGRSGSPSPFQSSSSRSPPRSPATPSQDSSISQEPAFHATVDLIKKGHLEAARASLKGGPLRDELEEEIERDCESLRSFLYAAQIIDEISPRSQDSIVGTGERLACKIVAAALRDRGVDSELVVLDNIVDASMSAASEAVSVDAGDQGVAQLGQEFYDQLSFRLGERLRECGQRVPVVTGYFGPVPGSLLAQIGRGYTDLCAALCAVGLKASELQVWKEVDGIFTADPRKVPSARLVPIITPDEAAELTYYGSEVIHPFTMEQVIRARIPIRIKNVENPSGAGTVIYPDVGFPRGLDTEPPKAERIVEGVDERMPTAVTIKDEIIVLNIHSNRKTLSHGFLARIFGTLDRAGVVVDLISTSEVHVSMAMQDFLNRKRLERLVKDLEKIGEVTVSKDMAILSLVGRNMRNAIGSAGLMFASLARAMINIEMISQGASEINISCVIENKDAIKALNVIHESCLSYPRSPATEMAGLQLQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within ACT-like_dom_sf, ACT-like_dom_sf sharing conserved structural features; 2. The protein must be able to perform the nucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004072",
                "GO-Name": "aspartate kinase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            }
        ],
        "go_f_mapped": [
            61
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 526,
                "End": 599
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 450,
                "End": 526
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018042",
                "InterPro-Name": "Aspartate_kinase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 28,
                "End": 36
            },
            {
                "InterPro-ID": "IPR036393",
                "InterPro-Name": "AceGlu_kinase-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 428
            },
            {
                "InterPro-ID": "IPR041747",
                "InterPro-Name": "AK-Hom3",
                "InterPro-Type": "DOMAIN",
                "Beg": 25,
                "End": 427
            },
            {
                "InterPro-ID": "IPR001048",
                "InterPro-Name": "Asp/Glu/Uridylate_kinase",
                "InterPro-Type": "DOMAIN",
                "Beg": 210,
                "End": 413
            },
            {
                "InterPro-ID": "IPR001341",
                "InterPro-Name": "Asp_kinase",
                "InterPro-Type": "FAMILY",
                "Beg": 177,
                "End": 597
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 526,
                "End": 599
            },
            {
                "InterPro-ID": "IPR054352",
                "InterPro-Name": "ACT_Aspartokinase",
                "InterPro-Type": "DOMAIN",
                "Beg": 538,
                "End": 596
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 450,
                "End": 526
            },
            {
                "InterPro-ID": "IPR036393",
                "InterPro-Name": "AceGlu_kinase-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 82
            },
            {
                "InterPro-ID": "IPR036393",
                "InterPro-Name": "AceGlu_kinase-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 174,
                "End": 427
            }
        ],
        "ipr_mapped": [
            480
        ],
        "response#1": "MPSFDISSEANMIEVDNAIEQFKKEMSTRFDFRGRDFEVSYEKDSKGPKGTIVSEVNMVEVKNAIEQSNKEISTRFDFKGSDARVEQKERELTLTGDGDFKLGQVKDVLIGKLAKRNVDVRFLDYGKVEKSGDKVKQVVTVKKGIDGDLAKKIVRVVKDSKIKVQASIQGDAVRVTGTKRDDLQSTIAMLRKDVTETPLDFNNFRD",
        "response#2": "MPSFDVVSKANMVEVKNAIEQSNKEISTRFDFKGSDARVELKERELTLYGDDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKVEKIGGDKVKQVVTIKKGISVNAFSWAVDSKCLCDFVIRAVSIGFAVSVGSAFPGFFTMPSFDVVSKANMVEVKNAIEQSNKEISTRFDFKGSDARVELKERELTLYGDDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKVEKIGGDKVKQVVTIKKGISGDLAKKIVRIVKDSKIKVQASIQGDAVRVSGTKRDDLQSTIAMLRKDVTDTPLDFNNFRD",
        "response#3": "MPSFDVVSEANMIEVKNAVEQSNKEISTRFDFKGSDARVEQKERELTLYADDDFKLGQVKDVLRGKMAKRNVDVRFLDYGKVKGDVKVSVKDVVEKVKKDTRLSISSGDVEVKVQDPDEVVFEDFDLTGESVFSESAEVVDSNGNAVLFEPKNIPAALNSITDDVKIESFTRFPDDIVFAVPTALNLTRTQTRYLSDHRQVISILEVTIPLFSASEERKIKDSGSDARVEQQERELTLYGDDDFKLGQVKDVLIGELAKRNVDVRFLDYGKIEKIGGDKVKQVVTVKKGIDGDLAKKIVRIVKDSKIKVQASIQGDAVRVTGAKRDDLQSTIAMLRKEVTDTPLDFNNFRD"
    },
    {
        "reference": "MSDNTPTPQKNPDTNPYASLISQQIAIIPSFTLESGVTLNNVPVAYKTWGKLNEKADNCLVICHALTGSADVEDWWGPLLGLNKAFDPTRFFIFCGNVIGSPYGTISSVTTNPETGKPFGPEMPGSSVKDDVRLHYIILKSLGVRSVAAVVGGSMGGMTVLEYPLNTPPGFVRAIIPLATSARHSAWCISWGEAQRQSIYSDPDYKDGYYYEIEEEGGKVDLARQPARGLAAARMAALLTYRSRDSFESRFGRRAGGGKSSVPKGGVRIMGGQETTDPSVPSESDLAAKSPSWRAWREHNDGHRSAGARPISRSGSEGPAHREGDAAQAEVVKTQDVKANGNKIGTGGEAPPKIFSAQSYLRYQGDKFTGRFDANCYIHITRKLDTHDLSAPSRDTSLSSLSSGLPSSPDATEEELNARLIHALSLEPPALVIGIESDGLFTTSEQRELAAGIPDAELVVIPSPDGHDGFLLEFEAINGWVEGWLKRKMPEFYERRVINPEEYVQGEEGFGIKKESVFGEAEADVTRW",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AB_hydrolase_1 that are essential for its biological function; 2. The protein should belong to HAT_MetX-like, HAT_MetX-like, HAT_MetX-like, HAT_MetX-like that shares evolutionary origin and functional similarity; 3. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 4. The protein must be able to perform the homoserine O-acetyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004414",
                "GO-Name": "homoserine O-acetyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004414",
                "GO-Name": "homoserine O-acetyltransferase activity "
            }
        ],
        "go_f_mapped": [
            87
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 60,
                "End": 245
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 496
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 486
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 486
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 489
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 29,
                "End": 400
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 488
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 60,
                "End": 245
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 496
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 486
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 486
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 489
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 29,
                "End": 400
            },
            {
                "InterPro-ID": "IPR008220",
                "InterPro-Name": "HAT_MetX-like",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 488
            }
        ],
        "ipr_mapped": [
            35,
            220,
            36
        ],
        "response#1": "METDSIGIVAPQTAHFAEPLRLQSGSVIGNYQLVVETYGELNAARSNAVLVCHALNASHHVAGVHADTGKPGWWDNMVGPGKPLDTNRFFVIGSNNLGSCFGSTGPMSIDPATGKPYGARFPVVTVEDWVHAQARVADAFGIERFAAVMGGSLGGMQALAWSLMYPERVAHCIDIASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYGHNPAPGGDVFAVESYLRYQGEKFVDRFDANTYLLVTRALDYHDVSRGRGGLTAALAHTQAKYLIASFTTDWRFAPAESREIVKALLDNRRTVSYAEIDAPHGHDAFLLDDARYHNLIRAYYERIASEVGVEGAA",
        "response#2": "WVHAQARLADAFGIERFAAVMGGSLGGMQALEWSLMYPERVAHCIVVASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYAHGVKPKRGLRVARMIGHITYLSDDSMGEKFGRALKADALNFGFDVEFQVESYLRYQGDKFVDYFDANTYLYITRALDYFDLARGRGGLTAALAHTQAKYLIASFSTDWRFAPARSREIVKALLDNRRTVSYAEIDAPHGHDAFLLDDARYHNLIRAYYERIAKA",
        "response#3": "MPTDSIGIVAPQTMHFAEPLRLESGSVLGNYQLVVETYGELNAARSNAVLVCHALNASHHVAGVYADDPRSTGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSIAPDGKPYGARFPVVTVRDWVHAQARVADAFGIERFAAVMGGSLGGMQALEWTLMYPERVAHCIVVASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYAHVKPKRGLLVARMIGHITYLSDDSMAEKFGRALRADALSFGFDVEFQVESYLRYQGDKFAGRFDANSYLLITKALDYFDVSRAFGGNVTAALAQ"
    },
    {
        "reference": "MTVKVRFDKEVRDYAKGEKVKDSILKLTETALAQALENFHRRMIVIEGDTLRKAELAGILAGASARVLSGILEELMKKRLRDESEDKIEVLYATDALGEETFGRKRYEAFRKHFDVLAGSNVEVKAVTFKHTRDILGRTYDLLILDMSYDYSPNDLGRIIETVRGGGLIFILAHPFEKWKNMWTGFHKSLVTPPYTIDDVKKRFNRRLIRKFTEHDGIYIITEGGKARKKPKRSKSQARIKARKGVPIPEETLFPKELYEMALTEGQVEVLKAFEELVEGGMLVLTADRGRGKSVSVGIGAIGLALALKKRTRIVVTAPELENVQALFRFAKRALERLGFKPYVVEERGLIKELYARKIGLRYYPPADGYKKSADLYILDEAAGIHVPILHKYLNKERVVYSSTIHGYEGAGRGFSVKFLKRAREKREFKELHMDEPIRYAENDPIERWLFDVLLLDAEPVELTEEDFELIEKKEVYLEEPDLDDWFENDREDLRNFVGIYILAHYRNRPSDVALLADAPHHEARVLRLKNGKIVTAIQIAKEGGIPKKVIEKMAKGYKPRGNIIPDMMVKHHYLKEFAKLKGYRIVRIATHPDAMDRGLGSKALELLEKEAREKGLDWIGSGFGASEELVRFWVRNGFAVVHLSPARNPVSGEFTAIVLKPISERAKKLIKKANDEFRIRLTEWLGDTHRELEPEIARWLFETPFGEAVDYPVHLTEIQKKRLDAFTGKVLTYDTVVDAVKPIVKLYFLDGWMKPYLDERQIRLLIYRVLQAHSWEETAKLIDRTETFTMIEVRDIIRGLWYYYKRLLKA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the N-acyltransferase activity,nucleotide binding,N-acyltransferase activity,RNA binding,tRNA binding,N-acyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:1990883",
                "GO-Name": "18S rRNA cytidine N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            },
            {
                "GO-ID": "GO:0106162",
                "GO-Name": " mRNA N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0019843",
                "GO-Name": " rRNA binding "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            },
            {
                "GO-ID": "GO:0051392",
                "GO-Name": " tRNA N4-acetyltransferase activity "
            }
        ],
        "go_f_mapped": [
            238,
            61,
            238,
            96,
            138,
            238
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 489,
                "End": 643
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 489,
                "End": 643
            },
            {
                "InterPro-ID": "IPR024914",
                "InterPro-Name": "tRNA_acetyltr_TmcA",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 805
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 259,
                "End": 396
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 280,
                "End": 447
            },
            {
                "InterPro-ID": "IPR032672",
                "InterPro-Name": "TmcA/NAT10/Kre33",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 609
            },
            {
                "InterPro-ID": "IPR007807",
                "InterPro-Name": "NAT10/TcmA_helicase",
                "InterPro-Type": "DOMAIN",
                "Beg": 284,
                "End": 457
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 473,
                "End": 662
            },
            {
                "InterPro-ID": "IPR013562",
                "InterPro-Name": "TmcA_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 221
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 497,
                "End": 610
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 611,
                "End": 663
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MSRDERRFGRRAGEALVRAALEGEAAALAAQVEGFERAAEVVASVLREAARRAEERIRDLERLLEERGRAGRPEVAELREALRELVRRLERGEARDEARRRPAAEAWRRGARAREEAAARARRELTRVESDAEARARVRARAAALLARFGAEGEPEEHEEAGRWWERVRAEVARLVERLLEEGEEGLEPEDLLERYRRRAAEVLSALGEGLEAGCEREGRGAWEERRRVLERLAAAAARAPAGAERDPRG",
        "response#2": "MAEEATEGGLEAEPGDALGPEERLRARARLRELREGLEAGGRALPPEEGPVLGRAARRARELREEAVGEAAARRRERGRDALESARAALRWEREVAREARRELEALERLERRLGPPRGRLDPRFELAAGRRWRARAEEPRRRALEAERARLEREGERDAAASERAEALRRHLEAALEAEREEQERAWAEEEARRLGSSAPERAREFEALEREAG",
        "response#3": "MGRREERGARGEGREEEAGAEGRRERAGAAEEARGGEGGAPEHRECRRREERGGGGEEGRVGGGEDADAVEGEGREVRGPVERRPPAGRAGEAARREDGGRWRELDRERRAEDAAEVEEAAERGAGSEGRSGRGREALRQVGEAEGRRAADEGAWREAREARRAGEARVGPGEAEEAAVRAVEARVAGEVEAAEAEQEGCGEARGRLAGEEARGEEEERAFGRATQRAEREEREGALRRRVEREGEGGGRAGEREGTGAAEAVEAEVAGAAERAALAARAAGEREGEREARPEGTGGREREGARVEAGGAEGSEAGAGAAEGWTPRGRDRRGVAPRERGGGARAAGEEGEVEGEREPERAAEGARGERAGEAAGEARAVGEVETEERERAGALCEG"
    },
    {
        "reference": "MTSGRGVSQMVTDDKLRYFLKKVTADLHETRGRLRELEEAAGEPIAVVAMGCRFPGGVRSPEDLWHLVASGRDAITPFPADRGWETAGLYDPDPDRPGKSCAREGGFLDDVASFDAGLFGVSPREALALDPQQRLLLEVTWETFERAGLTPAALRGTRTGVFVGTSSQEYAMLVHNARENFEGYSTGYLASVISGRLAYNFGLQGPAVTVDTACSSSLVALHQAAQALRAGDCTLALAGGVAVLATPSMFVEFSRQRGLAPDGRCKAFAAAADGTGWGEGVGLLLLERLSEARREGHPVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRRALAACRAVGGPGGRGGGPWHRDPAGRSHRGPGAAGHLRPRASRPTSFVARVVEVQYRPHPGRRRRRRCDQDGDGPAPRRTAAHPAYRRPHSTGGLVGGHRAAAHRGEGVAGDRPTPPGRRVLLRHQRHQRPCGAGTSRAGRLPRPRRTAGTAPGGDTAAALGALRPHRARPAGTGRPAARPYPRPPAPLPADTAHSLLVSRTLFGHRAVVLGDDRDELLTGLDALAGGGNAPGVLTGVAGEPRKPVLVFPGQGAQWEGMAAELYRESAVFRDRLRQCAEALAPHTGFSLVDVVCGAEGAAALDRVDVVQPALWAMLVSLAALWRSHGVEPGAVVGHSQGEIAAACVAGALSLEDGARIVALRSRLIAERLSGRGGMAFLGLPAGRAREWLAAWETRLGVAAVNGPSSVVVSGDAEALDGMLAAAEEEGVRAIRVAVDYASHSAQVATLEDELLAALPGITPRTAEIPFFSTVNGALIDTSALDPAYWYRNLRQTVRFESTVRRLLEAGHRGFVEVSPHPVLAVSVQEILDATATEGVVLASLRRGEGGLRRFLTSVGEAHVHGIPADFALPPGRLVDLPTLAFERRRYWLDAQPAAPAHQAEGSAGESAGESAGESAEESEAALFRQRLAGLPESERERAVLHTVCEQAAVVLNLTSAADLDTGKAFTDLGFVSMTAMELRNRLATATGIRLTPTAAFDHPTPEKLAAHLLSRLTGTAEPIAQPVAAPPAAGEPIAIVAMGCRYPGEVASPEELWELLAAGRDATSSFPANRGWNTDELYDPNPGRPGRTYVRRGGFLHDADQFDPQLFGISPREALAMDPQQRLLLEVAWEVLERARLSPASVRGSRTGVFMGISGQDYLPVLTASPDGGAGHLMTGTSTSVASGRIAYTFGLRGPAVTVDTACSSSLVALHLAIQALRQGDCSAALVGGATVLSTPGAFVEFSQQRALAPDGRCKAFAAGADGTGWGEGAGMLLVEPLSEARRQGHPVLALIRGSATNQDGASNGLSAPNGQAQQQVIRQALANSGLTTRDVDAVEAHGTGTALGDPIEAEALLATYGQDRPAQRPLWLGSLKSNIGHTAAAAGVGGVIKMVLALRRGVLPPTLHAADPTPHVDWSAGAVELLTEAREWPETGRPRRAGVSAFGISGTNAHVVLEQAPDPDPAPGSGLPHPAATLPAVPWPLSGRTAAALRAQAGRLHRFVLAHPGLAPADIGRSLAAGRAGLEHRAVVLGRDRDQLLAELATLAEGEGDDAGAAVRGTVRARSRMACLFTAGPGARSGPGRELYARMPVYAAAVDEAGAAFQALPARPLGETMALDEAPADPVLAQVLHFAEQVALFRLLDHWGTAPSHLLGHGPGEAAAAHCAGVLSLSDAAALLPALRATEDDIRRTVKELTFHPPRIPLVSGRTGRPLTPGELRSPEHWIALARETGTPAEGLRWLLADGVHHCLLPVPVDTAGIPGDLAEDGLLLLPDPSRDGTGATALLRALARLYVRGVAVGWDRMLADCGARLVELPTYAFQRGRYWPELAALPAAGPRPAGRADGQGGREFQERLAGASEEEREALLAALVRTHAAAALRLPDADAIDERTPLPELGFDSLTAVDLRNRLGADTGLRLAPSLVFQHPTVTALARHLLAAWTAAGGADRAAEDTTGAGTTLGPLLARAGELGRSEEFQELMHRMAAFRPAFDTPRAEHRIPPVRLSRGPAAPGLVCFPTFAGSSGPQQYARLAAAARGERDLWVLPAPGFSWDQPLPASVDALARLQADGVQECAEGQPVVLLGYSAGGWIAHATAAALEARGAGPSGVVLLDTYWPDSAMLPRLHARIDQDRKSGSSEAHWTEEIRDDAGLTAMAHYSRLFQTWRPAPITAPTLLVRAAEPAVAEPPRDWRPHWRLPHTAVDAPGTHFTLIREHGPAALGSVHHWLNGLQKKEH",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within Thiolase-like, AB_hydrolase_fold, Thiolase-like, ACP-like_sf, Thiolase-like, ACP-like_sf, ACP-like_sf, AB_hydrolase_fold, Thiolase-like, Thiolase-like sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 298,
                "End": 336
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1903,
                "End": 1968
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 975,
                "End": 1041
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1930,
                "End": 2259
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 43,
                "End": 299
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1927,
                "End": 1942
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 963,
                "End": 1045
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 967,
                "End": 1078
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1061,
                "End": 1437
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 950,
                "End": 1049
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1878,
                "End": 1976
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1897,
                "End": 1972
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1900,
                "End": 1972
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 973,
                "End": 1045
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1989,
                "End": 2262
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1066,
                "End": 1502
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 45,
                "End": 336
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 298,
                "End": 336
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1595,
                "End": 1710
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1903,
                "End": 1968
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 975,
                "End": 1041
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1930,
                "End": 2259
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 578,
                "End": 895
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 576,
                "End": 864
            },
            {
                "InterPro-ID": "IPR036299",
                "InterPro-Name": "Polyketide_synth_docking_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 11,
                "End": 43
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 43,
                "End": 299
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 334
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1063,
                "End": 1489
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1064,
                "End": 1314
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 292
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 300,
                "End": 336
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1322,
                "End": 1439
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 1442,
                "End": 1561
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1927,
                "End": 1942
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 963,
                "End": 1045
            },
            {
                "InterPro-ID": "IPR001031",
                "InterPro-Name": "Thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 2045,
                "End": 2257
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 967,
                "End": 1078
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1061,
                "End": 1437
            },
            {
                "InterPro-ID": "IPR020802",
                "InterPro-Name": "PKS_thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 2046,
                "End": 2258
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 577,
                "End": 880
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1714,
                "End": 1814
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 45,
                "End": 455
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1066,
                "End": 1492
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 950,
                "End": 1049
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1878,
                "End": 1976
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1897,
                "End": 1972
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 1227,
                "End": 1243
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1900,
                "End": 1972
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 973,
                "End": 1045
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 579,
                "End": 877
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 703,
                "End": 768
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1600,
                "End": 1781
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1065,
                "End": 1709
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1989,
                "End": 2262
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1066,
                "End": 1502
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 45,
                "End": 336
            },
            {
                "InterPro-ID": "IPR015083",
                "InterPro-Name": "NorB/c/GfsB-D-like_docking",
                "InterPro-Type": "DOMAIN",
                "Beg": 12,
                "End": 39
            }
        ],
        "ipr_mapped": [
            35,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "FENENFFENENFEKFENENFKKFSNSNSNSNSNSNSNSNSNSNSNSNSNSNSNSNSNSNSNSKFEKFEKFFEKFEKFEKFFEKFENFFEKFENENFEKFGNENFEKFFEKFEKFFEKFEKFEKFEKFEKFFEKFEKFENENFEKFENENFENENFEKFFENRNFENFFEKFEKFFENFNFENFSFFPPPFPPPPLPPPFPFPNPPPPPPPPPPPPLPKPPEPPPPPNPPFPPEKFEPPPPIPPEKPKPFPPPPPPPPPPKFPPFPPPPPEPPPNPPPPPPPPPPPPKFENDNFKNFNFEFEKFFENKFEKFRNFKNFNFKFSNLNFNFEKFEKFFEKFEKFEKFFEKFENFFEKFEKFENENFEKFENENFFEKFEKFFEKFG",
        "response#2": "MHDQARRFTSSRTSTTTPTSTPLPTTPTTTPSSSSSSSPPHHPNPNPSPSSTCTSPIPPTHTPTAPRTITPSPSSPSSTTSSASPSSSLVHPSSRPRTRRTTRPNPSRIRPLRLRRPRPRRRHRPTRRTRTHPTTRPSPTTRPSRALRTTRTKPTTPSTRSTPTARSTRTTRTTPTRPSRRRRPSRRRPTPSTPSPGPSSSSSSSSSTRSSAASTPASSSLSARRRR",
        "response#3": "MKKKFGNENLNFFENEKFEKNLFEKKKFSKNLNLNFFLENQNVIFKEKNFENKDENEKIYNFKILSKNKTIKNEKKVNFFFENSKIINKKNLNSNENIFFENLFFFKENLNEKKEKKYENKNLFENLNLNKIKNEKKFNENNKNVENFYFFNENEIKNSNFFFLKNPIFFKNFNLKNNLKNFFFFFFEINKNLKIFKKNIIFENLILEKFKINNENFLKFKNIEKKKNEKKKKEKQNLNQNLNENENLNKKNIFDKIFFENKKNNFFYKKNFKKNNLENENENENIKNENKNNEKFEKKNLNLKKFENKEKNIEKNFKNFEKIFEIPFNKNKNYEKNLFLNFFYFFLKNFLINEKNLLKNFFENRISLFKNFYHNI"
    },
    {
        "reference": "MPVGDDKLVEALRASLKETENLRARNRELRAAAREPVAVVAMGCRFPGGVKSPEDLWHLVAEGTDAISPFPADRGWDTDSLFDSDPGRPGHTYVLEGGFLDDAAEFDADLFGISPREAVAMDPQQRLLLETAWETFERAGINPASLRGRPVGTFVGSVLTTNGGGAEPAEGSEGHQLTGSAASVLSGRLAYTFGLEGPAVTVDTACSAALASVHLAVQALRQRECAMALAGGSAVLTTPGIFVEFSRQRGLAPDGRCKPFAAAADGTGWGEGVGLVLLERLSDARRRGHPVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALAAARLSADLVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSVKSNLGHTQGAAGIAGLIKMVLAMRHGVLPRTLHIDRPTPHVDWSSGAVRLLTENREWPPTGRPRRAAVSSFGISGTNAHVILEQAPAEGEMTDGPEGADIPAVGLPLVLSARGDRALRQQAERLAAHLRARSGLRPPDVGHSLVTSRATLDQRAVVWSGDRDGLLAGLDALAQDRPAPGLTRGTATEGALAFLFSGQGSQRPGMGRQLAGEFPVFAEALDEAAGHLDPRLDRPLREILHAEEGTPRAALLEQTAFTQAALFAYEMAMFRLLTHWGITPALLLGHSVGELAAAHAAGVFSLEDACTLVAARGRLMQRMPGTGAMVAIQATEAEVLPLVAARAGEISLAAVNGPCSVVVSGAEGAVLEVAGYWKERGRRTSRLRVSHAFHSPQMTGMLQEFGEVAGKLEFHPPRIPVVSNLTGEIATDEQLCSPEYWVRHAQAPVRFHTGMRALVAAGVRTFMEVGPSGTLTAMAQDCLAEQPAATGAVVIPVARSGRPETGTTLAAVSRAFVQGTPVDWTRFFPQTGNRRVELPTYPFQRRGYPWSRASATAQVTAAGLAGLRHPLLGACLELADGQGTVFSGRLSRRTESWLAHHKVLGTALVPGTAIVEMALRAGTEARCGRLVELTQEAPLTLPDQGAVHLQVRVGAPGENGHRSLGVYSRPEEAPDWVCHARGQLAPEAAAPPAAPGEDWPPPGAEPVPLEGFYERLAAEGLDYGPAFRGLSRAWRLGEAVFAELALDRTARAGAGAYGVHPALLDSALHLALLDGALAGRSRLRIPFAWQDVSCHGAGAPALRARLTPAGTDSVSLALWDEHGAPVASVGSLVTRPITAGQLRATRTQDTLFHLNWAAAEPVPGAAPGCVVLGDDDLAAAVAAPGLPGPEALLAALDSGESIPGLVLLPCRAPDADTPDADDPLAAARSLTGRVLEVIHHWLTDARLTDSRLAVITRGALSAADGEPVTDPAAAALWGLVRSAQSEHPGRFLLADLDGHPGSTAALPAALSGNEPQLALREGRLLVPRLARGVPEGSLMPPPGAAEWRVAPAGGGTVDDLVLAPCPEAAAPLAPGQVRVAVRAAGLNFRDVVMALGMVADQRALGGEIAGVVTEVGPDVPGLAPGDRVFGLAAGCLGPVAVADHRLIAPMPPDWSFPQAAAVPVTFLTAFHGLVDLAGLRAGEKVLIHAAAGGVGIAAVQLARHLGAEVFATASPAKWDAVRALGVDEGHLASSRTGEFEARFAGSGGVDVVLNSLTGELLDASLRLLRPGGRFVEMGKTDIRDAARIAGEHQGVRYRAFDLMDAGPGRIAEMLAEILALFERGRLRPVPVRTWDVRQAPAAFRFLAQARNVGKLVLTMPPAWDPSGTILVTGGYGALGTEVARHLVRTGRARHLLLAGRRGPEAEGMAELTEELRKLGALSVRAVACDMAERASVAELLASVPAEHPLTAVVHTAGVVDDGLLESMTPRRLDTVFRPKADGAWHLHELTRDRELAAFVLFSSAAGTLGAAGQANYAAANAFLDALAAHRRDAGLPATALAWGMWAGTGGMAAALDRAGLDRVSRSGIAGLSTEDGLALFDAALAADRAVWLPIRFHTPALRTAAGQGSLPPLLRGLAGTPADPAAPAGAANALRERLAALAPGERRPAVRELVRGQVAAVLGHPTAETVDPQRPFKELGFDSLTAVELRNRLGAMTGLTLPSTLVFDHPTPDALTDAIEARLPAGPGAPAESFLARLDDWAAGLAAAPLDQDERERVAARLRALALRWEEGTRPQDTGPAVAGELDLATDEEVIDFISNELGIS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, Thiolase-like, NAD(P)-bd_dom_sf, Thiolase-like, ACP-like_sf, NAD(P)-bd_dom_sf, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,oxidoreductase activity,phosphopantetheine binding,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            152,
            4,
            24,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1523,
                "End": 1697
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 407
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1216,
                "End": 1400
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2022,
                "End": 2088
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 472
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2014,
                "End": 2100
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2017,
                "End": 2092
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1730,
                "End": 1973
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1997,
                "End": 2095
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2020,
                "End": 2092
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2047,
                "End": 2062
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR015083",
                "InterPro-Name": "NorB/c/GfsB-D-like_docking",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 31
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1523,
                "End": 1697
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 407
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1426,
                "End": 1560
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1238,
                "End": 1398
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 197,
                "End": 213
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 565,
                "End": 856
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1424,
                "End": 1726
            },
            {
                "InterPro-ID": "IPR002364",
                "InterPro-Name": "Quin_OxRdtase/zeta-crystal_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1551,
                "End": 1572
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 566,
                "End": 874
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1443,
                "End": 1498
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 292,
                "End": 409
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 938,
                "End": 1038
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1216,
                "End": 1400
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 927,
                "End": 1215
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2022,
                "End": 2088
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 472
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 568,
                "End": 871
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2014,
                "End": 2100
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 459
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1736,
                "End": 1915
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 694,
                "End": 759
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2017,
                "End": 2092
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1730,
                "End": 1973
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1997,
                "End": 2095
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 938,
                "End": 1099
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1064,
                "End": 1211
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 412,
                "End": 522
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 938,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2020,
                "End": 2092
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2047,
                "End": 2062
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 462
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 2091
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 567,
                "End": 888
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 35,
                "End": 284
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MNKLIKKKIFRFFLKNNTIDIFFKKYNFKIKNKNFFYFFFKNNYKYYFSKILNFNNNGIKKNFIHLNNFNINYNFKNFSKFIYFKFNYFFIKNKFFYINFDINFIYNFFISDNFYFSFFYLNDNKLKLNYENFKIFKQINYYLNFNLSNINKNYFFDKIIYLNKFKNLNLKNSNCFRIFNFLNKNKNFRNFPIFKKNFFNKNSILNKIFYKINIFFSNKNCNFYFNFLKTKNLKNKRIFLKKNFYQFLDFKKNSFYNFKIEIFYLKKKKKINNFYLINKKKIFNFFNNKNLFIKKKIFLVLKNTNKKNYFNFKNLKNKNEKINFNLINLKKHSNKNLIKINKNIINLKKNKNKFKNIKLNNFKFYN",
        "response#2": "MNTIKKILKGIFKNTFFKNINFKNNNLFNNFFKNKSNFNIIKKKKIIKINIKFNFINFNNLFLNFLFLRNNKFSNKIKKKLSNSIISFKNFFKIKNNFINKNFFNLNFFNVFFFFNNQKDISFILIKKITIPKKIKLLKNNKKKFNSKYFNLFKIKIFFKNKHKNNLNKNFLIFNDNNKNDKPIFIFNFFGLNIIMLNLLINFFFLKLIFFNFKNIFNNFFFFKFKKLRKI",
        "response#3": "NKNKNQIKINNLFRNNKIIFLNISSISIKIKNLKINFFRFQNRKINNFLNIKKKLFNFFRIFNNFYNKKNFLRKNFLNRKKFLNFFQINIFKNKINSKNFFQIKKYNFNQKRFKKHNLKIKNNLNFLKKIFKNNFLINSNNLIKNFNFLNFRKNFNFSNLNLNKNFIFKLFRINLLKNLKNQNFFKNSPKNFQNSFKKINLRNRKICNFFKNSVKKKNLNPFQNLKKNFLNLKNLENKNFSNLNFLKLNLNFFFNFKKIIFFKNLKKFSILNKNNLNLFKKNNFNLKNFYFLNKFKILNFFQNLNKNFFHLNFFKKNLNFIFLNNLNLHLNLIFLNKIFKKNFKKKFFFLNFFNKKKFFKIKIFKKKKFHN"
    },
    {
        "reference": "MTKDDKTLDYLKRLTAELVQTRERLRTAQAASREPVAVVSMACRFPGGVSSPEELWRLVAAGRDGITPIPAGRGWDTEGLYDPDPDRVGKSYAREGGFLDDIASFDAGLFGISPREALVMDPQQRLLLEVSRETLERAGIAPGTLGGSRTGVFTGLMGGDYTARLPGILGEFEGQLEIGRAGSVASGRVAYTFGLEGPALTLDTACSSSLVALHLAVRALRDGECDLALAGGATLMSSPAALLEFSRQRALSPDGRCKAFAGQADGTGLAEGVGVVLLERLTDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRAALANAGLTAAEVDAVEAHGTGTTLGDPIEAQALLATYGRRRDPQQPLWLGSLKSNIGHTQAAAGIAGVIKTVMALGAGQLPPTLHIDHPTPHVDWSEGTVRLLTEARPWPDTGRPRRVGVSSFGISGTNAHVILEQAEQPPAEDNPSRPLSPVPWVLSAQTPRALRAQAARLRDHLADAPVPHPADIAYSLAVTRDALRHRAVVVGRDPGELLRGVSALADGEPAPGLVEGEAREVGRTVLVFPGQGSQWAGMAQPLWRHSTVFRERMEACAEALAPHVDWSLREMVDAPAEDARWDRVDVVQPVLWAVMVSLAGLWRSHGVEPAAVVGHSQGEIAAACVAGALSLEDGARVVALRSRLVAERLAGKGGMVSVAAPVAEAEDRLARRPGRLALAAVNGPSSVVVSGDPAALEELLADCARDGIRARRVAVDYASHSPQVAALREELLAALAPIRPRAGEIPLYSTVTGGPLAGERLTGEHWYRNLRQTVRLAGTVRTLAAAGHSVFVECSPHPVLTPGLTETLTGLDEDALVVGTLRRDDGGPERFLCSLGELFAGGRAPDWERVFTGTGARRVALPTYAFERRRHWLDAVRPQGDPVPAGLSPLDHPWWGAVTELPEDEGWLLTGRLSRESSPWLGEHTVDGNVLLPGTAFLELALQAAEEAGCAGVAELTLQAPLLLPARGGIRLCAVVGAAGADGTHPLTLHARPEDAPDAPWTRQATGTLTRTARPAEPMPEDWPPPGADPLPVDRIYGELAALSLEYGPAFRGLRAAWRRGEELFAEVALDESGESQGFALHPALLDAALHPVAADEDADGPRLPFSWTGVTLHAVGANRLRVRIGPAGPDAVTLEAADGTGAPVAFVESLAVRPLTPGSGAPAAVTPADSLFAVDWTPAPAAPSATSRTWAVLDGAESLAPAIEAAGCEVLRRPDLTAAIAAPGLPDAMPAARDLGLGERSDAAPGLPDAMLAARDAAPGELSAAVPEPPDVVLAALDPGRGELPAAAREVTGRALALAQRWLAEDGPSRLVLLTRGAVAATGTETADPALAAAWGLLRSAQSEHPDRLVLVDWDGQPSSAAALPAAVSGDEPQLALRGGRILAPRLRRLPVTRPAPQAFDAEGTVLVTGAAGVLGRVITRHLVRTHGVRRLLLVSRRGPEAPGAAELTAELGELGASVRWTACDVADRAALADVLARIPARHPLRAVVHAGGLLDDGVVSALAPDRLETVFRPKIDAVVNLHELTSDLTAFVLFSSAAGTFGTAGQGGYAAANAFLDAFAGLRRSQGLPALSLAWGLWAETSALTARMSDTDRDRMHRSGVTGLSGAEGTALFDAALAAGPPMVLPTRLDLAAVRARAAAEGVPALLRALVKPPARRAGTATESGSALARELAALAPQDRAGAVLETVRAQAAAVLGHTGTAEVEPQRAFKELGFDSLTGVELRNRLARVTGLRLPATLVFDHPTPHSLAAHLLGRLTGGQRPRSTAPHAPARPDEPIAIIGMACRFPGGIASPEDLWRLLERGGDAISAFPADRGWDLDPAEYTAEGGFLREAARFDPEFFGISPREAVAMDPQQRLLLEITWEALERAGLDPTALRGSRTGVFAGLMYHDYTVRHAAAPGEAAGYLGTGGSGSVASGRIAYTFGFEGPAVTVDTACSSSLVALHLAAQSVRAGDCELALAGGVTVMCTPSAFTEFSRQGALAADARCKPFAAAADGTVWGEGAGVLLVERLSEAQRQGHRVLAVLRGSAVNQDGASNGLTAPNGPSQERVIRHALATARLRARDVDAVEAHGTGTTLGDPIEAQALLATYGQDRPAGRPLWLGSVKSNLGHPQAAAGVAGVIKVVLALRQGVLPRTLHVDRPTPQVDWSQGAVELLTEARPWPETGRPRRAAVSSFGISGTNAHVVLEQAPAPAEHDPQPAAVPGPLPLVLSARGEPALRAQAAGLRERLTADPGLQLADVAGSLLTTRAALEHRAVVLGDGRAELLAGLAALAHGRETPAVVRGTACAPGKTVFVFPGQGAQWPGMAAELWESSPVFRKRLGECAEALAPWVDFDAVEVVRGTATGIDPERVDVVQPALWAVMVALAGLWRSYGVEPAAVVGHSQGEIAAACVAGGLTLADGARVVALRSRALTALAGRGGMLSLALTPAEAGKLVAGRGDDRLSLAAVNGPESVVVSGDTDALEEVLAHCERTGVWARRIPVDYASHSPQVAEVRAHIQRDLAELRPRTGQVAFFSTVTGRFEDTAGLDGDYWYRNLREPVRFEPAVRELAGLGFGAFVETSPHPVLTTAVGEALAGRPGPPPVVVGSLRRGQGGPLRFLASVAEAHTRGIAVDWSTLWAGRTPRVVDLPTYPFQRRRFWLPAPAASGEVTAAGLGRAEHPLLGARMELADPPETVLTARWSLDTHPWIADHTVADTVIVPGTAFLELALLAGAETGCPQVRELIQQAPLVLAERGAARLQMRIAPPAEDGTRALAIHSRPEDASPEEPWLCHARGLLSEEEPATPPALDGSWPPPGAEPIELVGFYQHLDEIGLGYGPAFRGLRAAWRLGEEILAEAALPEPQQDETAGYRAHPALLDAALHSCLLRGRGERPEAAAMPFAWNDVACHADCGPAVRVRVTPGAGQEVSVVVADVQGSPAVTIRSLAARPVPAGQLRAAGGRSGSLFHLTWTPAPTDTGASPGAWAVLGEDDPGLALPYFPGLPALWAAYDGGATAPELVLAPLAGGPGDGPERSRELTCRALELLQSWLADDRTETRRLVIVTRGAVTASDDDPPPDPAAAAVWGLVRSAQSEHPGRFLLADLDRHPDSAPALTAALATALALDEPQLALRAGRVLLPRIQRAPAAQEGTPPWDPQGTVLITGASGTLGRAVARHLVTTHGVRRLLLVGRHGGAGEEAARLTTELAGHQATVDWAACDAADREAIAAVLASIPAAHPLTAVIHAAGVLDDGVLPALSPQRIDAVFRPKADAARHLDALTRTASPPALVVFSSAAATLGSAGQANYAAANAFLDALILARRRAGFPGQSLAWGLWSETSEMTAALGQAGRARLARSGLQGMPTEEALALLDTALATDRPLLLPMRLDPPALREGAGPLPPVLRGLVRAPARRGGPGRAEDAAALRRRLAALTPAERDRQLTDLVRAQAATVLGHPGAEAVGRDRAFKELGFDSLTAVELRNRLSTATGLRLPPTLVFDHPTPAALAGHLSTRLAPDDDPPDAPHDSEREVRRALAAIPLTRLRDAGLLDALLELAGRPAAGAAPPDDGEPGSIDRLDAEGLLAMALNNQAHAETEDHDAGW",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PKS_PP-bd, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within Thiolase-like, Thiolase-like, ACP-like_sf, NAD(P)-bd_dom_sf, Thiolase-like, NAD(P)-bd_dom_sf, Thiolase-like, ACP-like_sf, ACP-like_sf, ACP-like_sf, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3492,
                "End": 3507
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 476
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1801,
                "End": 2234
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1725,
                "End": 1797
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3465,
                "End": 3537
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1721,
                "End": 1830
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1206,
                "End": 1430
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1752,
                "End": 1767
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1811,
                "End": 2179
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3462,
                "End": 3537
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1441,
                "End": 1677
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 407
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3458,
                "End": 3546
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3442,
                "End": 3539
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1703,
                "End": 1800
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1727,
                "End": 1793
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3467,
                "End": 3533
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2987,
                "End": 3169
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3177,
                "End": 3430
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1722,
                "End": 1797
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2336,
                "End": 2656
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 564,
                "End": 881
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3492,
                "End": 3507
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 476
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1801,
                "End": 2234
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 197,
                "End": 213
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1725,
                "End": 1797
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3465,
                "End": 3537
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 930,
                "End": 1200
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1721,
                "End": 1830
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1815,
                "End": 2231
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 292,
                "End": 409
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2064,
                "End": 2181
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 689,
                "End": 754
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 930,
                "End": 1092
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 2704,
                "End": 2868
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2461,
                "End": 2527
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 561,
                "End": 850
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2336,
                "End": 2640
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 563,
                "End": 866
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1332,
                "End": 1426
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 3064,
                "End": 3165
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1206,
                "End": 1430
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1752,
                "End": 1767
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1811,
                "End": 2179
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 1969,
                "End": 1985
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3462,
                "End": 3537
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1441,
                "End": 1677
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2693,
                "End": 2985
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 919,
                "End": 1202
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 2704,
                "End": 2981
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2334,
                "End": 2623
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 3059,
                "End": 3170
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1054,
                "End": 1197
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2837,
                "End": 2980
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 407
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 459
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3458,
                "End": 3546
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 2704,
                "End": 2804
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 930,
                "End": 1030
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3442,
                "End": 3539
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1703,
                "End": 1800
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 284
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1816,
                "End": 2056
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 3182,
                "End": 3361
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1443,
                "End": 1620
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1727,
                "End": 1793
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3467,
                "End": 3533
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 412,
                "End": 528
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 2184,
                "End": 2300
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2987,
                "End": 3169
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 565,
                "End": 863
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2338,
                "End": 2637
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3177,
                "End": 3430
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 462
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1818,
                "End": 2234
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1722,
                "End": 1797
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MKNSENSENFENFQKFSENSENFQNFQNFQKFQNSENFENFQKSQNFQKFQKFQKISENFENFENSEKFQKFENSENSENFQNSENFQKNFQKFSENFQNSENFQNSENFQKFQKSDFSNFQNSNFQNSNFENSNFENSNFQKFQKSQNSDFQNFEFSNFEFSNFENFQNFEFSNFENSNFENSNFQKFQKFQNFQNFQKFQKFQNSQNFQNFQNFQNFQNFQNFENSENSENFEKSQNFEKFQKFSENFENFQNSENFENFQNSENFQNSNFENSENSENFQNSQNFQKFQKSEKFQNFQTSENSENFQNSENSEKFQKSQKFQKFQKFQKSQNFQKFQKFSENFQKFQKFQKSENSENFQNFQKFQKFDFQKFQKFS",
        "response#2": "MSSPLCSSSPIPLIFSKSPFLKRAQILLLFFSFFLFLLIPFSFFFFLFFFLFLFLFTFPLSHLLSFFSSSSSLNLKLHSLKILPLNSSTSPSPSPSSSSSSPSPPSSNSPLNSFFSPSPDHYTFLLPSSSPKSSKSFLSKANSFFTSSPFFPSSFVLFSLIFLIIFPLIKPLSSSIIIPETGASQSSIYPSLFSIFLIRLFLLLFPLLPSLPPFPLLFFFLFFFFPPTCPLLSLQLPSKSFFSLSFSSNKPSFPPPLSNLPFFLITPPFVLFFFLFFFISLSLLLKTQNLFDSILK",
        "response#3": "MAPFPRTRSSSALASRRSRARSRAPAFHSVVPTPTSRTRRPTTVPTTPTTPTPTATRAAPRRASSASPPTRPSRRGRRPRRRRSRRPRRRRSRRRRRRRRRPRPARRTTSSPSSPRTSPSRCSSGSLRSRRTSSPSRLLLSRATGRTSPRHPHRHTPPRVTTTRRTRTSSTPTSPAPTLSASPTSPSPTPTSTSPTPTSTPTSPTLPTPPAPPRTTTTPPPLSTPTPTSSPASTSVPTSSTTVPSSPRRTSSAPTTSPRADTSTRSPPSTLSAERRRPGARRG"
    },
    {
        "reference": "MELNGIRRRLATAKEAERHRLLLELIRAAAAEALDRPGPLPLDPGRAFGAQGVRGRAAGRLRERLSEATGLPLPATVVFDYPTPGALAGRLCALLLDEPAGPGGANGQMEAEEPIAIVGMGCRLPGDVRSPEGLWRLVHNGTDAISEFPEDRGWTVQQHPDPDHLGTTVTRHAGFLYDAPDFDAGFFAISPGEAVTIDPQHRLLLETTWKAVEDARIDPTSLRGSRTGVFVGLMYSEYGARIRRVPPGAEGYRVVGSMPSVASGRLAYTFGFEGPAVTVDTACSSSLVAMHLAAQSLRKGECTLAVAGGATVMATPWGYIEFSRQRGLAPDGRCRSFSADAAGSSWSEGVGVLLLERLSDARRHGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALAHAGLTTAEVDAVDAHGAGTRLGDPIEAQALLATYGQGRPAGRPLWLGSLKSNIGHTQAAAGAAGVIKMVMAMRHGVLPRSLHITEPTPHVDWTSGAVELLTEARDWPADGRPRRAAVSSFGVGGTNAHIILEQAAPEPERPHAPEADGEPRPLPWPVSGHGAAGLRAQARRLADFLRAGPAAPDADLAYSLATTRATLTDRAVVVAADRAEAIARLTALAEGDQGPRVARATAVPRDRLAFVFPGQGSQWPGMAAELMSCYPVFRESIKECGRSLAPHTDWSLAKVLRGESGAPTLDRVDVVQPALFAVMVSLAALWRSFGVEPSAVAGHSQGEIAAARVAGALSLEDAARVVALRSRALRVLSGRGGMVSVAAPAGQVLRTLERWGGAVSVAAVNGPRSLVISGDPGALGEALAAFEAEGIRARRIPVDYASHSAQVEEIRDTLLTELSGIRPRPATVPFYSTVSGEPLDTTALDTGYWVRNLRDTVQFDRTVRRLLADGHTTFLEMSPHPVLTPGIQETAEEAGADEVLTVESLRRNEGGPARLLTAVAEAHVHGVAVDWSPAFAPHRSPARRPAVLRLSSGAATGLRTRPRPPPMFTTAGLDGIDHPLLGAAIPLADGGGGTLFTGTLSLATHPWLADHAVADVLVVPGTALVEAALRAGAECTGRAMLEELVLQAPLILPEQGTVRIQLSVGGPDGTGRRALILSSRPEDAGADEPWTRHAEGTLAPGGGHPRQDPGPWPPTGAREIDLDDCYRQLAKTGLHYGPAFQGLKRLWRLADDLCLEAELPDSAGESGRYGLHPALFDAALHAAALAGPSGAEPLTRLPFSWSGVALYTAGATRLRARLSFTGPQSLTLTAMDPLGHPVLSVGTLGMRPVTAEALHRAAGTAGTALLRLEWRRQAPEHPAGPDLTGWAWVGAGAPPAQPPDGRPYRDLAALRAELDAGAAVPPVIVLAEPATPEGTDPFTAARAALHRTLAAIQDWAAEERLAGTRLVVLTQGAVAATPGALPDPALAAVWGLVRSAQAEYPDRIGLVDTDDPGRSRAAVAAAVHAGEAQAAVRDGALLVPRLARVTATDGPGGPAWPADGTVLVTGGLGTLGRLVVRHLVTTHGARRLVILSRSGGDSAEVREFVGELLAQGANVQVVKGDAADPAVLERVLDGIPQEHPLAAVAHLAGALDDGVLAAQTPQRLDRVLRPKAEAAWQLHRLTARARVPLLAFSSLSGVLGPAGQAGYAAANAFVDALVQRRRGTGLPGVSMGWGMWATRSGLTGALSDTDARLIARTGVRPLTDEEGLALFDQARATGEPVVFPLGLDITALNSGAPDGIPPLLRGLTARTPARRAGAAEAPEPAGEDLAARLAATPEAERDALLLGVVRGHIAAVLGYDDPRAVAERRPFSDIGFDSLRALQLRNRLGAATGRRLPATLVFDHPNPAALSRYLRTLLLPDPAPAPTAPDGQPGPDQADQVIERLNSASLEEVLDFIDHQLGE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within Thiolase-like, NAD(P)-bd_dom_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, NAD(P)-bd_dom_sf, Thiolase-like sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 109,
                "End": 535
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1492,
                "End": 1707
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 97
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1777,
                "End": 1852
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1773,
                "End": 1862
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1760,
                "End": 1852
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 127
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1783,
                "End": 1848
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1807,
                "End": 1822
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1296,
                "End": 1480
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 104,
                "End": 552
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 23,
                "End": 95
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1780,
                "End": 1852
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 1012,
                "End": 1289
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 109,
                "End": 535
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1492,
                "End": 1707
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 97
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 369,
                "End": 486
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1777,
                "End": 1852
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 645,
                "End": 943
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1141,
                "End": 1288
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1002,
                "End": 1290
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 1012,
                "End": 1177
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 274,
                "End": 290
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 115,
                "End": 539
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1012,
                "End": 1113
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1773,
                "End": 1862
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1760,
                "End": 1852
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 127
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 112,
                "End": 536
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 641,
                "End": 930
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 644,
                "End": 962
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 361
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1783,
                "End": 1848
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1807,
                "End": 1822
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1296,
                "End": 1480
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 768,
                "End": 833
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1483,
                "End": 1848
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 489,
                "End": 586
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 643,
                "End": 946
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1360,
                "End": 1476
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1494,
                "End": 1671
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 104,
                "End": 552
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 23,
                "End": 95
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1780,
                "End": 1852
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "FGKNFENFENFEKNSDFGKKNSDFGKKNFENFGKKNFENFGKKNSDFGKNFGKNSDFGKKNFENFENFENFGKNSDFGKKNFENFGKKNSDFENSDFGKNFGKKNSDFGNSDFGKNFENFENFEKKNFENFENFENFENFENFENFENFENFENFDFENFENFENFENFENFENFENFENFENFENFENFENFENFENFENFENFENFGKNSDFGNSDFGKKNSDFGKNFGKNFGKKNSDFGKKNSDFGKKNSDFGKKNSDFGKKNFENFENSDFGKNFGKKNSDFGKNFGKKNSDFGKKNFENFENFENSDFGKKNSDFSDFGKKNSDFGKKNSDFGK",
        "response#2": "FKTDPSPQIPIIKNNFNKIKNQINKNFNFQNIFTNFNFNLKNKKNPNKNLNFFYFFNLKNFKNFLNPPKKKNAIHPNNSNFNFLNFSPKNLKNQKKNFQNFNLPNFFKNLKIENIFPQKNFQKKNQKRFKSSLNFNIQKKNNLKIHKNYFNKNPNIFFFSNNNFNFRKNFIFNFKNLKKNPKNFIKFKNIRNKIFFNNFNKFKFNLIQNFLILNIKFIKSLNFNFNKIKKIQNPINFLQ",
        "response#3": "KNFEKDEKNFENEKFDEKNDENFDEKNFDEKNFDFEKFDENFDEDENSDFENFEFENNENENENFDFDNENIDKENSNIDFENSNFDSENSNFENSNLENSNIENFHSENSNFENSNFEKSNFENLNFEKNFEKKNFEKNSDEKNFDKKNSEKKNFEKNFEKFEKNFEEKFKNFDEKNSDEKNSDEKNFEKNFENSEFENSEFDEKNFENSNFENSNFDFENSNFEKKNFEKSENENFDEKNFENSENDEKFEKFDEKNFEKFEKFEKNFEKNEKDEKFEKNEKFENEKFE"
    },
    {
        "reference": "MKKRCLITGGAGFIGSHLAEELVKRGHPVTIVDNFYKGKSKYHEELTGNIPIIPISILDKNSMHELVNQHDVVFHLAAILGVKTTMEKSIELIETNFDGTRNILQAALKGKKKVIFASTSEVYGKGTPPFSEDDDRLYGATSKIRWSYAICKTLEETLCLGYALQGLPVTIVRYFNIYGPRAKDGPYAGVIPRFIRAALQGDDLLVYGDGKQTRCFTYVSDAVEATIAAMDEKVNGEIINIGSEDEKSIQEVAQDIHQLTHSSSKIVHVPFEKVYPHGFEEIPNRKPDVTKLKEMCQFHPNVSWEQGLKETIQWFREIEND",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Epimerase_deHydtase that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the NAD binding,lyase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0070403",
                "GO-Name": "NAD+ binding "
            },
            {
                "GO-ID": "GO:0048040",
                "GO-Name": " UDP-glucuronate decarboxylase activity "
            }
        ],
        "go_f_mapped": [
            22,
            32
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 318
            },
            {
                "InterPro-ID": "IPR001509",
                "InterPro-Name": "Epimerase_deHydtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 242
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 318
            },
            {
                "InterPro-ID": "IPR044516",
                "InterPro-Name": "UXS-like",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 317
            },
            {
                "InterPro-ID": "IPR001509",
                "InterPro-Name": "Epimerase_deHydtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 242
            }
        ],
        "ipr_mapped": [
            208,
            7
        ],
        "response#1": "MTRTVVVTGGAGFIGSNLVDALLERGDRVVVVDDLTDVALPERAEFRRADVRDAEGLRAALDGADAVFHQAACSATEWDGRRVFENNVRLSEVVLDACLDRRLPLVYASSAATYGGRTGMFREDTPVEAPLNVYGYSKHVFEQVARRRMAEHPDAQLTGLRYFNVYGPREDHKSRMSVVHHLDGQVRRGERPRVFGDGEQTRDFVYVGDVVDVNLWVLDHPEVSGVFNVGTGRAESFNDVARAVIAHRGGPEPEIEYVPFPEHLRGRYQAFTQADLSRLRAAGYTAPRRDFATGVAETLAWLDRQPA",
        "response#2": "MRPAAPSDGPSPPARRPGPARTARTIPRRRRARPAVSAPPPRTAPPPARTTGAARTGRRSTGTGTRRAGTTGTGTGRDPGRPVRPAGTGRTARPRTPAGTAAAARTACRTDRQPARTGRRQPTGRGGRTAAGTPRRVPVPARAPTAAVRRPAGAAGAAPRTGPARTAARSAPPSTGTRTRRSAPRTAPAAGRTPPARRPPARTPRRRAARTVRPAAPAPGPGPG",
        "response#3": "MPVRRCADDRRSRRSDRRSDRRSRRRSRSDRRSRSDRRSRRARPRSRRSRRSRSRSRSRRSRRRRRRRRRAVRTRAVRTRTRAVEADAGGAGTGAVETATSPDGSADGPHGSGRPATDRVETVADRATPADAATDAATDAAADTVATTVTDAAPATATTATTTAAATATDGRTATATVTVDPGATADPATTATTVQTAAADARVVVEPDGSVVVTADR"
    },
    {
        "reference": "MANSWRISALRERHLALGSQLEDWNGMGTAWTYASDLADHHEAIRTRAGLMDVSGLKKVHYVGPHAESLLDYATTRDIGKLYPGKSVYACLLDEDGKFIDDCIVYRTGPNAFMVVHGAGTGHEMLIRSAQGRQVAVLFDDDLHDLSLQGPRAVDFLAEHVPGIRDLPYFHHLQTKLFDRPVMISRTGYTGERGYEIFCKAADAPAIWDAILEQGKGYGIIPCAFTALDWLRVESYLLFFPYDNSQMYPFADQKAGDTLWELGLDFTVSPGKQDFRGAGEHYRLKGQERFKIFGVLLDGHQAAQGGDTLWHDGRQVGVITCSMYSRLTERSMAIARVEPQIAEQGVPLQVRGSLDCAAIAHSLPFDDPEKKKRTAKG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GCST_C, GCV_T_N that are essential for its biological function; 2. The protein should belong to GcvT/YgfZ/DmdA that shares evolutionary origin and functional similarity; 3. The protein should be classified within GcvT/YgfZ_C, TrmE/GcvT_dom1 sharing conserved structural features; 4. The protein must be able to perform the transaminase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008483",
                "GO-Name": "transaminase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008483",
                "GO-Name": "transaminase activity "
            }
        ],
        "go_f_mapped": [
            34
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029043",
                "InterPro-Name": "GcvT/YgfZ_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 290,
                "End": 372
            },
            {
                "InterPro-ID": "IPR028896",
                "InterPro-Name": "GcvT/YgfZ/DmdA",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 370
            },
            {
                "InterPro-ID": "IPR027266",
                "InterPro-Name": "TrmE/GcvT_dom1",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 374
            },
            {
                "InterPro-ID": "IPR013977",
                "InterPro-Name": "GCST_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 291,
                "End": 364
            },
            {
                "InterPro-ID": "IPR006222",
                "InterPro-Name": "GCV_T_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 242
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029043",
                "InterPro-Name": "GcvT/YgfZ_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 290,
                "End": 372
            },
            {
                "InterPro-ID": "IPR028896",
                "InterPro-Name": "GcvT/YgfZ/DmdA",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 370
            },
            {
                "InterPro-ID": "IPR027266",
                "InterPro-Name": "TrmE/GcvT_dom1",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 374
            },
            {
                "InterPro-ID": "IPR013977",
                "InterPro-Name": "GCST_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 291,
                "End": 364
            },
            {
                "InterPro-ID": "IPR006222",
                "InterPro-Name": "GCV_T_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 242
            }
        ],
        "ipr_mapped": [
            326,
            327,
            328,
            329,
            338
        ],
        "response#1": "MVVNSATREKDLSWITQHAEPFGARLTDVSDDLSLIAVQGPNAQAKAATLFTDDQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQDMDETISPYAANMGWTVALKTDRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVAAY",
        "response#2": "AVKAEATGDAGITDVSDSLSLIAVQGPNAQEKAATLFTDEQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTVALKTDRDFIGREALEVQREHGHEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVAY",
        "response#3": "MAAQQTPLYEQHTRCGARMVDFGGWMMPLHYGSQIEEHHAVRTDAGMFDVSHMGIIALQGSRTREFLQKLVSNDVATLKPGKALYTAMLNASGGVIDDLIVYYTGEDGFEIVCNSADAAKLWDAIVEVAAPEGGLKPIGLGARDTLRLEAGMNLYGQEMDETISPLAANIGWAIAFDWEPADRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVVA"
    },
    {
        "reference": "MSGYSAPRRISDADDVTSFSSGEPSLDDYLRKRALANHVQGGSRCFVTCRDGRVVGFYALASGSVAHADAPGRVRRNMPDPVPVILLSRLAVDRKEQGRGLGSHLLRDAIGRCVQAADSIGLRAILVHALHDEARAFYVHFDFEISPTDPLHLMLLMKDARALIGD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016747",
                "GO-Name": "acyltransferase activity, transferring groups other than amino-acyl groups "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 150
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 143
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 150
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 162
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MSGPASRDPDPHRDLAAAVRRALDAIDVGLDDAYADRLAAEGRADTLARRAAWLVRALARTDGLAVAGPGRPAAPPGEPGPDDWERRLARLHALVGRGPAPPAGTAPADAAPPATPRPARPRTRPGARPRRGRPPAPRQRTRPRRHRRRGRPRRRRRARPAVPAPSPPRPPLPARVPARRPRGRRRAPSVRLAAASRTGGRPGLPHPADAVLELAARPDRAALDRLRRALLARIPAPADDVALRTALRPAGLRPRRRPAAARPPAPRPAPRPPAPRPLPVPAATAEAPSPPPDGERTGLRRRVSAVVRRLLHRR",
        "response#2": "MPRKRKPPPPAPPPPPPPRPEAPPPPPPPPPPPPPPPPAPPPPPPPAPPPASELEALRRELEALPAENATLREEVRRLEAALEAARREAEAREAERRRLEAELKALRAEAERARAEAEERLRALEAALEATRRELEELRRAPPPPEDAALERELARLREEVRAAREERDRWRAEAERLRAELEAREAERRRLEAEREALARALEEERAAREAERRELEAALARREAELAAARAEAERLRAALEEARAAPFEARLRALEEALARARAEEARLEAALRETQARLAEAEAALERAREEARRREAELARLREEERRLREREEALRKELERVRRVF",
        "response#3": "FEKNFEKIKNFEKFSEKFEKFEKNFEKNFEKIKNFEKFSENFEKNFEKNFEKIPNFSEKFSENFLKNFEKIPNFSEKFSEKFEKNFEKFSENFEKNFEKISENFEKNFEKIKNFEKNFEKFSENFEKNFEKNFEKNFEKFSEKNFEKILNFEKFSEKIPNFSEKFSENFSENFEKNFEKFSEKFSENFEKNFEKFSEKFSENFEKNFEKIPNFSEKFSENFEKNFEKNFEKILNFEKFSEKIPNFSENFEKNFEKISEKIKNFEKNFEKFSE"
    },
    {
        "reference": "LIGVKTEHGYLLDKYTGCKVWCVINNESCNGECKRRGGYYGYCYFWKLACFCQGARKSELWHYETNKCNGRM",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more LCN-type_CS_alpha_beta_dom, Scorpion_toxin-like that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL/defensin, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002061",
                "InterPro-Name": "Scorpion_toxinL/defensin",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 54
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 7,
                "End": 69
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 56
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 69
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 17,
                "End": 24
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 49,
                "End": 62
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 33
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 47
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002061",
                "InterPro-Name": "Scorpion_toxinL/defensin",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 54
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 7,
                "End": 69
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 56
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 69
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 17,
                "End": 24
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 49,
                "End": 62
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 33
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 47
            }
        ],
        "ipr_mapped": [
            64,
            65,
            61,
            62,
            63
        ],
        "response#1": "MNSLVMITACLVLFGTVWAKEGYLVRKSDGCKVSCLWGNEGCDKECKAEGGSYGYCWTWGLACWCEGLPDDKTWKSETNTCGGKRVKASDQFYSSYASLWDLASLCDDNGKLIRKLYLVVYYHFAKPFTRIQVSNWKIRRVNDAPDGYIRGRDGCKVSCLIGNEGCDKECKAYGGSYGYCWTWGLACWCEGLPDDKTWKYETNTCGKKK",
        "response#2": "MNSLLMITACLALIGTVWAKEGYLVNKSTGCKYECFWLGKNEGCDKECKAEGGSYGYCWTWGLACWCEGLPDDKTWKSETKTCGKTSRRGDCIIVGPDKAAKDVGITHLTGKGIPTGKKAIGKNVGFKEKKIKTECITYPGVEYFVIEKCTKEGGRGEPAEKNHVKKVISKTDECYVTTDKEKFKTTIIFGVVDLTTGKVKVDKRGSTFINISGININENASLEVDKDIAENEENIADGRDGYIRGSDGCKVSCLIGNEGCDKECKAYGGSYGYCWTWGLACWCEGLPDDKTWKSETNTCGGKK",
        "response#3": "MNSLLMITACLVLIGTVWAKEGYLVNKSTGCKYECFWLGKNEGCDKECKAYGASYGYCYAFACWCEGLPDHVPTWPLPNKSCGGTKENLPVQTVRNIHVKNLFAVNTFLIVVTELPSQTSAPEDPSFNDPIGTDGSPKNWTAAKVGTKVKVSKKVNGKKVKPNSYVCLSFKAGVGACGNWMKRSRTSTCGESGTFLTMSTSEDSRDGYIRGSNGCKVSCLIGNEGCDKECKAAGGSYGYCWTWGLACWCEGLPDSVQVWSSSTNTCGKK"
    },
    {
        "reference": "MKAIISVSPGRAALVHDRPLPSLRNGYLLVRTKAVALNPTDWKHIEITERPGILFGCDYAGVVEKIGPGISSRFQVGDRVAGFVHGGNSQEPQDGAFAEYILAKADIQILIPEHMSFEEAATLGVGVTSVGQGLYQALQLPFPGTQGEDPKTPTEEQQPLLIYGGSTASGVLGIQFAKLSGFAPLAVCSPDHFDLVETLGAVAQFDYADGEEAVQEIQDYVDRMSKPLRLAWDTVSIPSSAQFCGDALSALDECHYASLLPIKCQRSDVTSTTTMAYTVFGEDWGMGATRFPAVATDAEFGRRWWALVQELLDQGRIQTHRIIIGENGLDGVLAGLERLRDSQVRGAKLVYRV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the nucleotide binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding "
            },
            {
                "GO-ID": "GO:0016651",
                "GO-Name": " oxidoreductase activity, acting on NAD(P)H "
            }
        ],
        "go_f_mapped": [
            61,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 115,
                "End": 322
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 26,
                "End": 112
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 115,
                "End": 322
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 350
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 140
            },
            {
                "InterPro-ID": "IPR047122",
                "InterPro-Name": "Trans-enoyl_RdTase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 353
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MWRGVVFCLSSEFAKDHPRRRERWRMGRLKDKVAIITGASSGIGEAIARLYAREGAKVVLTARRVDRLEKVAADIRKEGGEAMVVPADVTKSEDVKAMVDKTLETFGRIDILVNNAGIERDATVESMSEKDWDDVINVNLKGVFLCMKHVLPHMLKQGSGSIINISSIAGLVGNVGQANYAASKHGVVGLTKSVALEYAPKGIRCNAIAPGYIETEMTAVVPEKDKQAAIDRIPMGRWGQPEEVAYAALFLASDEASYVTGQVLAVDGGYTAR",
        "response#2": "MSGPTPASPGLRGKRVLVTGGAGFIGSHLVEALLEQGAEEVRVLDNLTTGSEENLERVRRRSGGRLAFVRGDIRDRELLREAMRGVDVVFHQAAIVDYTVRDPRPCLEVNVLGTLNVLEACREAGVRRLVFASSSSVYGEQERQPRREEDEPEPLNPYAVSKLAGEHFCRLYHRLYGLEVTALRYFNVYGPRQDPRGEYAAVIPRFALRALKGEPLTIYGEGEQTRDFVYVDDVVEANLRAALAEEARGEVFNLGTGREVRIVDLARRVAELAGAGDPERLIAFGPPRPADVRRAYADISKARRLLGWEPRVDLEEGLRRTLEFLRRELGERG",
        "response#3": "MGDEIKKALVTGGTGFLGSHVVEKLLEEDIDVTVFGRNPDKMDEKHKEKAKFVKGDITDKDSVKEAMKDQDLVIHLAAKIGSTDFDTINDVNVKGTRNVLDACVENDVKRLVFISSGAVYGDHKENLNVKAKEDMKVDLENVGSPYPESKRVSELLCQEYKKKHDLDITILRPFNTYGPRDTHDVIPRFVKNALEDKDLTIFGDGKQTRTFVYVDDMADAIVKASQSDEAKGEVFNVGNDEEVSIKELAELVKEKTGKDVEINFQEKPIDDVQRRYADVSKIKELGWEPKVSLEDGVDKTIEYFKD"
    },
    {
        "reference": "MKTEDMALVFSKLILNPITKRQILNLFKKDDNGNLIIENYIDAYMKGEDINSLGYKTLKSVLDNGLKTFAGEIYKENFKDFLKDPLFKKGLISVVRGLGYFGVKRPFVSGAPFLVVWDVTYACNLRCKHCYANAGKPLEDELNTEEALKTIDILANSGVVAIAFSGGEPLMRKDLFELIDRAKDYNMQVSIASNGTMLNKTNAKKLKEHKVDFVQISLDGTKETHEKFRGIKGIYDKTIEGIKNVVDEDIFCAIATTATKLNYRDVPKVMDLAEELNVNYFMLYNYIPVGVGDYDIDLSPEEREELLNLLWEKLNNDTGKKYRTAFLSTAPYYSRTALEHNKYYLASHFANVDLGENERLKSLANFIGGCGCGRFYLSLRANGDIQPCVFFPLKLGNIKSFKDENDFLEFWRNNKILNDLRDRDKLKICGSCMYKYVCGGCRARAYSYYDDYLREDPGCILTKNLK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, rSAM, rSAM, rSAM that are essential for its biological function; 2. The protein should be classified within Aldolase_TIM sharing conserved structural features; 3. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            79,
            183,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 309
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 119,
                "End": 272
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 118,
                "End": 464
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 100,
                "End": 317
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 114,
                "End": 422
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 309
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 119,
                "End": 272
            },
            {
                "InterPro-ID": "IPR050377",
                "InterPro-Name": "Radical_SAM_PqqE_MftC-like",
                "InterPro-Type": "FAMILY",
                "Beg": 109,
                "End": 460
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 118,
                "End": 464
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 100,
                "End": 317
            },
            {
                "InterPro-ID": "IPR023885",
                "InterPro-Name": "4Fe4S-binding_SPASM_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 370,
                "End": 459
            },
            {
                "InterPro-ID": "IPR023867",
                "InterPro-Name": "Sulphatase_maturase_rSAM",
                "InterPro-Type": "FAMILY",
                "Beg": 118,
                "End": 464
            },
            {
                "InterPro-ID": "IPR023885",
                "InterPro-Name": "4Fe4S-binding_SPASM_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 370,
                "End": 432
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 114,
                "End": 422
            }
        ],
        "ipr_mapped": [
            195,
            196,
            101
        ],
        "response#1": "RHRHHHHHHHHHHHHHHLHHHHRHHRRRHPHHHRRQLHRRQRQPHPHHHHHPHHGQHHHHHHHHHHHRHRVRRRRHRHPQPRPPTPRPPRRPPPPPPPPPPPPRRRPPPPPPGHRQQQGQRGRPPPPQQGPPPQQQQPPPPPPQQPPPPPHRHPAPRPPQQPPPRPQHHPPQHQQQQHQQQQQQRQHPQRQQHHHQQPQQPPPQHQQHQQHQQHQHPQRRGHQQQQQDPQHHRQDPPHHPRGRRQHRRRAQRRHHRGRQPPRRHHHGHPHQPQQHRRHQQQPRGRQQQRRGQRRHGRHQQRRRRQHHRPRHRRDRPRQQQQQQRQQQHPRHHHRRRHHQPPGRQPRHQRQPRGRRGRLQRGGGGGRGQPPPQEQPRQR",
        "response#2": "HGPHPHGPHRRIHQPGRRHRAALQPRHRRQPPHRRQPRLHQGRHQRRQRQRHHGQQQRRQGQPEPGRRPPHRAPRRQQRQQGPQRRHQQQRPPQGEAGHRQPPPRQHRHHGRPGGRLPQHHLHEHGAQQRVHRHERRRHHRHRGQRQPGRRQVQRRAAPAPPRQRRGQRQQPRQQQRREHGRQLRQTQRGGRRRRRRPQQPRRRVGQLHQQGPPQVGAAPPRPQPQPQPLPQPQPQPQPQPKPQPKPKPQPKAQPHPPQRPQQQQPPPPPPQPPQPPQPPQPPQPPQPPQQPPQPPQQPQQPAGPPVQRRPAAQGVRERQQRRHRAAGGPAGGGGGGD",
        "response#3": "HLQQHQRPRRHQRRHPQRGPHHRQPHRHLHCPQHPQRRQRQHHHRPPRHHQPHHRQGPQARPHHRHHPRHPQRPQPQPHPPRHQPQQRRQHPPRQPRPPQHPQPPPPPSHPRHHQHHPRQRRQHPQRRHQPPHHRQHHHQPQPRRQPHPQRQQRQRHHPRRQEQRHPRRCQPPQQLHPQHHQPPRHQPHRRQHQPPPQHHPPQPLHSHPRPQQPRPHHRHLPQPRPQRQPPHPQPHHPQRRHPRPRRQQPHRRRQPRHQQRRHQQPPPRQQHHLHRQQPQPRRQPRHPQPPHRQPHHRQPRQPQQRLRPPPRRNRLHPQGPHPP"
    },
    {
        "reference": "MGLFTDLVLYGIVLPALPFIMRNRFHIPNAELQHYTSGFLATYAGASVFFSVPAGWAASKLGSRQLFLGGLVFLFVATAIFAFSTSLALLVVSRLLQGMSTAVVWTAGLDMVQDTVDPSQIGVTIGTIFATISVGELAAPVLGGVLYERGGIAAVFAVSAVMLAIDLGLRGLVIDKKAAVKFESPCLIRSSAERSDHVASAPTVVEAQERTHEGTPLLPQDDDDDSDRYKIDRELGSIVQAIPLLYCFREPRLHLAMLLSFVQALFIGTFDATVPTEAESLFHFSSLQVGLVFIALMLPYFALGRLAGQAVDRFGTKAAATSGYAFLVPCLLLLGLPEKKLVSKEANVALFCTILALNGIGLAVVTSPGYVEAIDVTTKYQVANPGHFGENGPYAQLFGFSSLYFFTGLAVGPLLGGVLRAKFGYAVMGAVYAAISGVTAIVSFLFVGTRRGVCWG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more MFS_dom that are essential for its biological function; 2. The protein should belong to MFS, MFS that shares evolutionary origin and functional similarity; 3. The protein should be classified within MFS_trans_sf, MFS_trans_sf, MFS_trans_sf sharing conserved structural features; 4. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 196
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 245,
                "End": 451
            },
            {
                "InterPro-ID": "IPR020846",
                "InterPro-Name": "MFS_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 451
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 452
            },
            {
                "InterPro-ID": "IPR011701",
                "InterPro-Name": "MFS",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 166
            },
            {
                "InterPro-ID": "IPR011701",
                "InterPro-Name": "MFS",
                "InterPro-Type": "FAMILY",
                "Beg": 257,
                "End": 449
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 196
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 245,
                "End": 451
            },
            {
                "InterPro-ID": "IPR020846",
                "InterPro-Name": "MFS_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 451
            },
            {
                "InterPro-ID": "IPR050930",
                "InterPro-Name": "MFS_Vesicular_Transporter",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 450
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 452
            },
            {
                "InterPro-ID": "IPR011701",
                "InterPro-Name": "MFS",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 166
            },
            {
                "InterPro-ID": "IPR011701",
                "InterPro-Name": "MFS",
                "InterPro-Type": "FAMILY",
                "Beg": 257,
                "End": 449
            }
        ],
        "ipr_mapped": [
            32,
            33,
            34
        ],
        "response#1": "MTASPYRTETQRNRLIILLGLLSAFAPLSIDMYLPSLPSLADVFHTDAGTVQMTLTSYLVGNAFGQLIYGPLSDKYGRRPVTLIGIGLYILGSLLCIVAPNIGLLIAARFLQAVGGSAGMVISQAVVRDLFTGKDSAKVFGYLSLVMGLAPITAPLAGGALLHFLPWNSLFIFLMLFGVVSWVMIYKGLPETLPDKKAQSGNYLELFKNPVYLGTAMTGGLLNAGLFAFISSSPIVFQSERGVSPLEYGFMFLPSALSLMVMNAVAAKLLNTKGSRPLILTGYSLGISGGLLYAFFAGQPAVSLTSLAFLLIGTGLGINTPSLNATAVGAAPKEKAGVASGVYGTVRFVGSAIGAALSGTVYNLGGLTTLSWMTAGIYLIGLLVTLFLLPKKVTG",
        "response#2": "MGVTVTATTLGLGAGALVIGPLSDRYGRRRPLLAGLTLYTLASLGCAAAPDIGTLAALRFVQGVGGAASMVLGTAVIRDSYEGPARAKAMSYYTIGSVAGPALAPAVGGLLADAAGWRWTFWVLAGFGALVWLLALLALPETLHPVLLRRRVARLRAENPALAAEAAAEAPGPRDRVAVLARPRVLAGYAAGFLTFTALYGTITFLPTVLQQGHGYSSGQAGLALLPLTAATMTGSLLGGRLVARLGDRPTAVAGLLLLAAGLAATAPVPAAALLGVAVAGLGTGCSVPALTATVIAGAAPATRAAATGVYNTFRFLGGAGGPALIGAVVTAAGWPAATTGMAVLCLLGAAVLAFGLPRTEPDAAASVEPAPETETHAE",
        "response#3": "MVLFVVQCWFQDKATMPPRILKNRTIWGSSIFTFCLSSAFLILVYYLPIWFQSIKGVSATKSGIMNLPLILSLVVSSILAGILTTKVGYYTPFMYTASIFMSIGAGLLSTFNVDTGTGKWIGYQIIYGFGIGCGMQQPIIAAQTVLPLKDVPIGTALVTFAQSLGGAIFVSVAQNVFQNQLVKNLATYAPGIDVQAVTNAGATQLRTVVPQDLLAGVLAAYNKALTQTFYVGVALAAVSIVGSAPMEWRSVKGKKVAEAEAPAEA"
    },
    {
        "reference": "MQTATALEDSANAPSPAASSQGQFDREIVPIDTADAGNSTKRSPLKVALIMVALCCAVFLHALDNTIITTALPTITAAFDLDAAYTWIGSTYLLAVAASTMVWAKISDVFGRKPIILSANLCFFTGSLIAALSANFAMLIAARAIQGIGGAGVNVLANICVGDLFSQRKRGLYYGVIGGVWAVALSLGPVVGGSLTESISWRWCFYINLPLCAVVFVIIILLLDVKTPKTPFGKGIAAIDWVGAALSIGSTLMILLALSLGGQTEPWNSATVICLVVFGFIGWILCFSWEASLAKYPLLPVSIFKQIPTLAVLAACFIQSYAFVASAYYLPLYFQAVLGATPILSGVYLLPTAVSISISSTATGVYMRKTGQYLTPIYIGFVLQTLGYGLFIDLGPTANWAKIIVFQIIGGLGVGFNFQAPMVALQAFISPRELAMATSAYNFMRNVSGAISVVIGQTVFQNEMSKHQESLATILGPQLAAKLAGTGASASTDLIRSLPSPQRDVVHGVFANSMKSMWIMYTAFSAAALVVCPFLGKMVLREDHTETVTGLAAENAAREERLRQEKEKKDAKIRKCQVN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more MFS_dom that are essential for its biological function; 2. The protein should belong to MFS that shares evolutionary origin and functional similarity; 3. The protein should be classified within MFS_trans_sf, MFS_trans_sf sharing conserved structural features; 4. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 237,
                "End": 476
            },
            {
                "InterPro-ID": "IPR020846",
                "InterPro-Name": "MFS_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 50,
                "End": 540
            },
            {
                "InterPro-ID": "IPR011701",
                "InterPro-Name": "MFS",
                "InterPro-Type": "FAMILY",
                "Beg": 54,
                "End": 452
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 35,
                "End": 540
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 237,
                "End": 476
            },
            {
                "InterPro-ID": "IPR020846",
                "InterPro-Name": "MFS_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 50,
                "End": 540
            },
            {
                "InterPro-ID": "IPR011701",
                "InterPro-Name": "MFS",
                "InterPro-Type": "FAMILY",
                "Beg": 54,
                "End": 452
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 35,
                "End": 540
            }
        ],
        "ipr_mapped": [
            32,
            33,
            34
        ],
        "response#1": "MGYAALFVRHELRAEHRMMDLRLFRSRAFTGAALASGLLNVVLTGLELVSTQHLQDVHGYSALRAGMVLLPSTVMVMVMAPVGERTLQRWGARRPLLAGTTTLVAGEVLTATLFAGPGWIAVPGFLLLGLGYGLSATELTDTAVASAPPEKAGAAAGVYNTASELGGAFGVAMVGAVYAAVRDPGTGPPEADALAHGATAALWTATGFAAISFAVAWRLIRPVPAEAAEEIGAMPG",
        "response#2": "MPTAPSTPRARRGSRPRQAVAAGPAVVPPTARAPPRTRTRSTPGSPRRWRRRRRRRRRPTRRESPRHHARPLPRRPAPRVRGHGVGVLLAAFPLAGTVGQVVGGRLAGRVRGRAAGSAALLVGAVAVLALGLLGDSVVPVLVAAAVAGVATYGHHTLQTTRVYAVSHTARPRVLGVFSAVQYVGQSAGAAVAAAVALVAVWPTTLVVAGVVSAAAAPLFLWLPEPTTRR",
        "response#3": "FVVELRAAQPMIDLTLFRNRTFSGATAASFLLGASMYGFLYLTTLHIQHIQGYSAVRAGLAFLPLTVMMMVMAPVGGRLLTTFGARLPMLAGVAAMTAGLLLLSRLPADSGYLTGLLPGFLLLGLGLGLSVTPLTDAAVAGAPPEKAGAASAVVNTSRQVGGAFGVALLGAVYAAGGGSDPAALVTGATTAATVAAAFAAAGFIVVLFLVPRARREAAAV"
    },
    {
        "reference": "MGPANSEGTMFDAFSREVGDYYDQANELLRAMFTDNVHYGYWPDPSSIDPLAEAGERMTEQLYERLDVSAGHKVLDVGCGVGKPAAWLARKTGATVKGANVSRNQLEVARDRVRSEGLEDRVSFDLADAMHLPYADDSFDRIWAIESMIHMPDRDQVMREMARVLRPGGRLAIADIVVRGTLDDVATAVVEGFCTLSTARSLEHIDNYPALVEKAGLDLLELTDVSEQTRPTGPAVLPAFDVLLPTLGEEGVAQSKKAWGDMFDLPQYGYVLLTAGKP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 278
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 11,
                "End": 278
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020803",
                "InterPro-Name": "MeTfrase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 29,
                "End": 278
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 278
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 11,
                "End": 278
            },
            {
                "InterPro-ID": "IPR050447",
                "InterPro-Name": "Erg6_SMT_methyltransf",
                "InterPro-Type": "FAMILY",
                "Beg": 15,
                "End": 179
            },
            {
                "InterPro-ID": "IPR013216",
                "InterPro-Name": "Methyltransf_11",
                "InterPro-Type": "DOMAIN",
                "Beg": 75,
                "End": 173
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MNKVALYCRPGFEKECAAEITDKAGQREIFGFARVKENSGYVIYELYQPEDGEKLIRELPFIGGRLIVVGELLKENTLSNFVRKVTVPLRDALPENEKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRER",
        "response#2": "MNEENELSKFCRKFTVELRAALRDAGVLTQETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQAKQLYHDREEVTVHVRRI",
        "response#3": "MAVDLTGGGPAAGCPGGRADTAARRGPAAAAPAAGPDGTDPDPGTGGGPSGRARGAPAGAGPAPRRGAGRRGRGRGRGPGPRRPAPGPRRPGRGPGPGPAAAPPGTGPAAGRGRRPGPPAPAPPPPGRGPPGPGPPAAPGTARAAARGARTGPRAPGAAPRRAGPAPARRARRAARLAGPDPGRRPAPPAAGRRAAPPAPRPAGPARARTRPARTGRGTGRAAAGPGDGPPGTARGAAPPAPAAGPRAARTATGARRRAPPNTGPPRRTGVRPTAVR"
    },
    {
        "reference": "MTDDQDVHLNSLDFQPISLLSFEGVAPYGPSCAQHKCHRCGPVLIDPGTCVYNNASMVLDNGAWAFHPGSYSTDLVANRSVEFLGDAIKAGEPFFLGVTPIAPHAETVGDAFEAPVPAKRHENLFLDVKVPRSPSFNAGAAGAVGYFRNLPKLAHDQIDYMDTFYRRRLQSLQAVDDLIEDIMAKLESHPDVLANTYLFYTSDNGYHIGQHRLPPGKTCGIEEDVNIPFIARGPGIAAGHVGRFPTSHTDLVPTIFELAGIPLRDEFDGEPMPLKGQRQSNDALNRNTYKTLRVDTDDYAFMYTVWCTNEHELYDMKMNNLYGSNSTTSSFDIPQLSARLDTLLLTLKACKGIACRRPWQTLFPTGNVNGLVDAMDPLHDSFFLVSQPRVTFTTCSLGYNAEVEGPLSPVIFGAADETAIEPRQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Alkaline_phosphatase_core_sf, Alkaline_phosphatase_core_sf sharing conserved structural features; 2. The protein must be able to perform the carbohydrate derivative binding,cation binding,hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0097367",
                "GO-Name": "carbohydrate derivative binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005539",
                "GO-Name": "glycosaminoglycan binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0008449",
                "GO-Name": " N-acetylglucosamine-6-sulfatase activity "
            }
        ],
        "go_f_mapped": [
            168,
            183,
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 46,
                "End": 322
            },
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 321
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000917",
                "InterPro-Name": "Sulfatase_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 59,
                "End": 261
            },
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 46,
                "End": 322
            },
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 321
            }
        ],
        "ipr_mapped": [
            512
        ],
        "response#1": "DAADAADAADAADATDAADAADAADAADAADDAAAAADAADDADDDDDDAADAADDADDADDADDADAADAADDADDEDAADDADDEDAADADEADDADEADDADEADDADDADDADDADDADDADEDDEADDDDDADETTTETETPTETTPPETTPPETPETPETPETTPPETETPPETEPPETEPPETTPPETTPPETETEPPEPEPPETEPPEPEPEPETPEPEPEPEPEPEAEPEPEPPETETEPEPPETEPEPEPPETEPEPPEPEPEPEPPEPEPEPPEPPPPEPEPP",
        "response#2": "MTDRPTDRGTDGPTVDVAAAGPADPADPAAARTVPADPADGTAAVAPVDPADADGPVDDATAAGRVDPVVADPAGDGDLPPPARSAVDVPVADDRADGDGDATGAADAADPVVDGPVPAVDPPRPAAPAAVDAPAVDGRGDGDRTGAPDGGPPVAGPVDGPDRAVVDDPPVRAGRADDGPADGPADVDRPPVRPPAARSVVDRPPGDDRAADADRPVDGTVDPSGRSAVDPPPPPPRPSADRAADDRVVDGADDRADDVAGDPVRARRDRAVDGPDDCPAGDRTSRDDGRPIRRRRP",
        "response#3": "MTDPRRADRRRPADRPAAPADPADPGPDRPPDRPDRPADRPDRPPDRADRPDRPAAAPAPAADRPDRAAADRPRPDRPRADAADPDRRPADRPDRAAPDRAAADRAADRPDHADRPDPDWADRPDPADRPDPDRPAGRPAADRGRTDDPAPDRTPDGPGDRPATAADPDRPGDRPDRRATADPDRTATAAADPDPDRTATTADPDRTATPADRPATTATADRSDRPTADPDRTDRPPADPDRAGTDPDRTATPAAADRPADGRPATDRFDATATDRRDPPATAADA"
    },
    {
        "reference": "MTQPCIISVAITGSLPRKRDNPAVPITVSEQVESTQAAFEAGATLVHLHVRNDDETPSSEPDRFARVLEGIRKHAPGIITQVSTGGRSGAGRERGGMLSLRPDMASLATGSVNFPTRVYDNPPDLVDWLAAEMKAYAIKPEIEAFDLSMIFQAVAMQQAGKIDGALHIQFVMGIKNAMPVDREVLAFYVHTLRRLAPDATWTGAGIGRDQLTMARWSLELGGHCRTGLEDNVRLDKQTLAPSNAALVSQVAALCEEYGRPVATVAQARALLGLPSMEIDGRSPW",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Aldolase_TIM sharing conserved structural features; 2. The protein must be able to perform the cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043720",
                "GO-Name": "3-keto-5-aminohexanoate cleavage activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 277
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR008567",
                "InterPro-Name": "BKACE",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 274
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 277
            },
            {
                "InterPro-ID": "IPR008567",
                "InterPro-Name": "BKACE",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 273
            }
        ],
        "ipr_mapped": [
            101
        ],
        "response#1": "MGKKNKKRKHQQRTAAERAAAAERARAERAAAAERARLERERAERERLAREEAERERLEREREAAERERLERERLAREEAERERLEREREEAERREAEREREEAEREREREARERAEREARERAEREARERAEREAAEREAREREAAARAAEREREEAARAERERAAEREAERAAEAEREREAARAARERAERAARAADPARVAAERRASQAERDAAFRAAAERALLEAAGLADPEVTEAEWDELLAALDAAPEPPSDEPDDPFDAATTTEILAIVATAQREPDTRFRPDPVPHVPATPDPAAVTLQAALEASPHRYRVREPHPDAPLPVLTPDPPRPEPAPPQPEPAARPEPELPEPDPPERPEPERPPR",
        "response#2": "MIDKKKIGENIKKYRKEKMLTQKELGEKLNVSSFQTVSKWERGINVPNIELLEKISKVLNISIEELFSFKEEKKEEKEEKKEEEKEEEEKKEEEKEEKKEKEKKEEEKKEEEKEDISGSWNRYYIEYDEEKEEKKYKIILNLKKINNKYEGEYYEDTDYKGNIKGEIKNNILKYEWKEEEYSGKGTLSFSSDFKSFTGEWIYGDEDDFNFNEYGTWTGEKINKIEENKHTKNKQLKNKKEEEKNKNEKIKKKSRNKK",
        "response#3": "MKKILVIYENKNEKLEEYIKKVKEENHEIYISGTKEIKEKYGEVVTEINKIEEYDEIYIPFLTSNTIAKIASLIADNEITKIVLKNINKKKIIVKNKNIEKEKYEGVKKNIKILEEYNIEIVEEEEEIKEKLNVNEVKEVKEVKEVKEVKEVKEVKEVKEKKLITKEYLENLDKNIKKLRVEKYTIITELAKEFIKENNMEIIEE"
    },
    {
        "reference": "MAAFADRPTCRVSLGAVFLARELHRLRKSLPLCVFSLFLFSFAFSALSGAPSQFAEAAMPKLSGEKLAELMQMDVKDIKERMLALFDLIDTNQDNTIDTEEAKEWSAKLKNAMHQHQVRMEFQAIDKDNDGKVSLSELEATYVDSLDQKQLEQHKKEVEQRFKTVDKDNDGLLDLSEIRILMDPGKDEGLMKIEIEEILNAQDKNGDRKITVTEFIETEGTGSLNDVEKTELEKEFKSYDLNADGAIDVEELQQIIKDPHSHEIRMLLEEFTKDLKDGKVGREQWEKEFESFAVSMLTDNGEVLRFPEDYSGIEFPFKTAVPQVDVDDEDKHDEL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair, EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            }
        ],
        "go_f_mapped": [
            31
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 166,
                "End": 178
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 156,
                "End": 217
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 80,
                "End": 140
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 153,
                "End": 188
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 78,
                "End": 217
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 191,
                "End": 290
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 231,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 117,
                "End": 145
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 81,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 157,
                "End": 185
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 194,
                "End": 222
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 240,
                "End": 252
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 148
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 234,
                "End": 255
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 203,
                "End": 215
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 227,
                "End": 262
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 126,
                "End": 138
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 77,
                "End": 112
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 166,
                "End": 178
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 156,
                "End": 217
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 80,
                "End": 140
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 153,
                "End": 188
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 78,
                "End": 217
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 191,
                "End": 290
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 231,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 117,
                "End": 145
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 81,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 157,
                "End": 185
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 194,
                "End": 222
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 240,
                "End": 252
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 148
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 234,
                "End": 255
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 203,
                "End": 215
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 227,
                "End": 262
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 126,
                "End": 138
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 77,
                "End": 112
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MKLAILLALVALCHADDKKKDDDKNDYNYKKWVEEDEKYFKLADKNCDGKITKEEFIEYKKAAGVKDEKDAEEAFKDADKNCDGKITEEEYLEDGKNDFDDADKDKDGYITLDELKKYYEDDDDDDDDKKKDDDKNDYNYKKWVEEDEKYFKLADKNCDGKITKEEFIEYKKAAGDEKDAEKDAEEAFKDADKNCDGKITKEEFIEYKKAAGVKDEKDAEEAFKDADKNCDGKITEEEYLEDGKNDFDDADKDKDGYITLDELKKYYEDDDDDDDKKKDDDDKKKDDDDKKKDDDKNDYNYKKWVEEDEKYFKLADKNCDGKITKEEFIEYKKAAGMKDEKDAEKDAEEAFKDADKNCDGQITLDELKKYYEDDWDEY",
        "response#2": "MEFRVALLLLLMVHCSCAKPKPTDKVHDDKQLHDDAQNFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVEKIDGDSDSFVTVEELKAWIKYAQKRYIYENVERQWKEFDLNEDGLVAWEEYKNATYNPDNPYDYQQMLVRDERRFKMADQDGDLIANKEEFTAFLHPEEYDYMKDIVVLETMEDIDKNADGFIDLEEYIADMHPEEDAEWVYVEKEQFTEFRDKNKDGKMDKEEITDWILPSDYGHAEAEARHFVYENDKNKDGRISKEETL",
        "response#3": "MHPPPPAAAAAAAAAAAAAAAASDDEEERDLREAFDLFDRNGDGRISADELGSVLGSLGLAGSTMDDCRRMISEVDADGDGFVDFDEFKAMMRGGGGGGGGGGGGGGGGHPPPPAAGMHPPPAAAAAAAAAAAAAAAAASDDEEERDLREAFDLFDRNGDGRISADELGSVLGSLGLGGSTMDDCRRMISEVDADGDGFVDFDEFKAMMRGGGGGGRR"
    },
    {
        "reference": "MSSHTSTPNHASAAPPRKWYDMTSAEFYVYVVAFMCGISMLMPINAVFSAPSYMLQYYLYATKDPNHVPQMTNFWSNVMTYYNLIGLVTGLVMEPLTLLKSFRKIPMLVRLLGGLCILIVEIIVLMAVPARGTTEGGAVATMCIAGFIGGLGKSIFESTVYGMFGAFPPSFTSIMMGGVGISGVLTSLIQIIVKAALPDTYEGVKKQSYIYYSLDVGIQAATFIALIMMRFNSFAQLHFGDLGGVKSKVDAGSLAGAGENVREPGAEATELEQYTEPAIGQIQEKNAEAHKDDPLVDREHSDDVDEHGDALRAVEGPTSNEILRATSIISVLRSIKWMFVSCAFVFVVTLFLFPGIATGMFPESKWFATVAVFIFNCCDVLGRVAPALRFMWPRSYNQRWIIVAASFARVIFVPLLLLYSYHYIPSEAYGYVIMVIFGFSSGYVASMSLTLGPQSKGIDNDGKRFVAGTLMGISILVGGTIGTVLSIMTQTIREKY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within MFS_trans_sf sharing conserved structural features; 2. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005337",
                "GO-Name": "nucleoside transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 333,
                "End": 487
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 151,
                "End": 488
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 25,
                "End": 491
            },
            {
                "InterPro-ID": "IPR034764",
                "InterPro-Name": "ENT1/ENT2",
                "InterPro-Type": "FAMILY",
                "Beg": 33,
                "End": 494
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 333,
                "End": 487
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 427,
                "End": 443
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 177,
                "End": 197
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 149,
                "End": 171
            }
        ],
        "ipr_mapped": [
            34
        ],
        "response#1": "MTPPATAPAAPRPDRRTLNAVAAGAFVANLGFGAVLPVLALYVREFTESPALAGLTAAAFGFTYGAFQLVWGPLSDRIGRRPVLLAGLGVFALGSAAVAFAPSIGWLVAARVVQGVGAAAVTPAALALIADTVSPARRGAALGTLGSAQYGGQAVGPAAGGVLAEVAGFRAVFVLAAVLAVVALPVVVRGVRPVRRGPAPARRPARSRGPRGGSSPPAGRGAVR",
        "response#2": "MGLLLLLMTGAGPAARVLSPTLPDSTTDAAELVDYVAVHADGYRAGYLLEAAGGLLLLPVVLGLGALVRRTGHRAATAATVLLVVSVIGWLVVSASDGAAFSLTLDRPDQARAVAMAVEGAFGPWPLLSALAFGVGTLALGIALIRAPAAPRWMGWLGIVAGAVVPLLFVDTNPIGLVAYATMAAWLAAATVAVVRRVRAPAVPVPA",
        "response#3": "MTPAPRPPQPRRAPQPPRAAPRRTPARPAPRPAAQRRPTTPARPRPAPARRPTRPTATGAPAPRPRRRRLAGAGLLVAGLVWTLLAVVSALVALSWQSTAGSWDGAPLGVVLLALGLPAVAAGVLSVRTPRAAVVGGALAAAPGGGVAAALLLAGAALGPVVAAAAVIAAALVATAGALVLRAGRRERRERAAASTAERTPAPAARPSRAELRAQRERERRREEERRRREEERERERREREQAEREARQRRRRQALGWLGAAVGVAAVLGVVVATGPGFVTVPSPDADVGDGVLRASAVVAAAAVVAGTVVAGIVTLVRRRRR"
    },
    {
        "reference": "MAQEMRYFSTRGGKETLSFEDAVLTGLAPNGGLYIPTHIPALPKDWKTKWAGLSFPELSHEILSLFVPTSVIPSDDLQSIINTAYSSFRSPATTPIRQTGDNEYVLELWHGPTWAFKDVALQFLGELFRYFLERRNKDKTEDMEELTVVGATSGDTGSAAIYGLRSKPSITIFILYPDGRVSPIQEAQMATVPDANVYCVAVEDSDFDTCQSIVKTLFSDAQFNATHRLGAINSINWARILAQIVYYFSAYFQLPEEARKDGAKLQFVVPTGNFGDILAGWYAKKLGLPMEQLVVATNENDILERFFRTGRYEADDAVQQDQTAETAAVNGSSDGQQAVSAVKATHSPAMDILLSSNFERLLYYLALETNGTEGSDEEKRFKAQERLNDWMSTLKKDGKVDLGEDVRQAAGKDFWAERVSDGQTLEEIQKYYRREKYGPYVVDPHTAVGLTAQERSAKKASPDTTWITLSTAHPAKFSGAVELALSASEFPDFDFRRDVLPDELKKLEGLEKRVHRVKGEEGVRALIEKVKSASHEKVDAEEGRGSL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more TrpB-like_PALP that are essential for its biological function; 2. The protein should be classified within TrpB-like_PALP_sf, TrpB-like_PALP_sf, TrpB-like_PALP_sf sharing conserved structural features; 3. The protein must be able to perform the pyridoxal phosphate binding,lyase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding "
            },
            {
                "GO-ID": "GO:0004795",
                "GO-Name": " threonine synthase activity "
            }
        ],
        "go_f_mapped": [
            33,
            32
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036052",
                "InterPro-Name": "TrpB-like_PALP_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 113,
                "End": 514
            },
            {
                "InterPro-ID": "IPR001926",
                "InterPro-Name": "TrpB-like_PALP",
                "InterPro-Type": "DOMAIN",
                "Beg": 97,
                "End": 349
            },
            {
                "InterPro-ID": "IPR036052",
                "InterPro-Name": "TrpB-like_PALP_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 504
            },
            {
                "InterPro-ID": "IPR036052",
                "InterPro-Name": "TrpB-like_PALP_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 519
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036052",
                "InterPro-Name": "TrpB-like_PALP_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 113,
                "End": 514
            },
            {
                "InterPro-ID": "IPR001926",
                "InterPro-Name": "TrpB-like_PALP",
                "InterPro-Type": "DOMAIN",
                "Beg": 97,
                "End": 349
            },
            {
                "InterPro-ID": "IPR037158",
                "InterPro-Name": "Thr_synth_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 90
            },
            {
                "InterPro-ID": "IPR036052",
                "InterPro-Name": "TrpB-like_PALP_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 504
            },
            {
                "InterPro-ID": "IPR029144",
                "InterPro-Name": "Thr_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 85
            },
            {
                "InterPro-ID": "IPR036052",
                "InterPro-Name": "TrpB-like_PALP_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 519
            },
            {
                "InterPro-ID": "IPR000634",
                "InterPro-Name": "Ser/Thr_deHydtase_PyrdxlP-BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 107,
                "End": 121
            },
            {
                "InterPro-ID": "IPR051166",
                "InterPro-Name": "Threonine_Synthase",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 538
            },
            {
                "InterPro-ID": "IPR004450",
                "InterPro-Name": "Thr_synthase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 74,
                "End": 342
            }
        ],
        "ipr_mapped": [
            1056,
            1057
        ],
        "response#1": "MRRHHRRRRHPHPRRRHPPHRPRRRRHRPRHRHRPRHPRRRPGRHRPRRPRRPHHRRRRPPHRRHPRPPRRRRRPHRRRHRPRHRPRPRRHHPPPRRPHPRHHPRLRPPLAPRHRPHDVRRRRAPPRRAPRRRPAAAPAAPPVPDAPVDVDVDVANPAAAAPAAPAAPAAPAAPVPVDAAAAPAPAAPAPAAPVPAPVAAPAPAVAAPVPLAPEDDVDDVDADDVDDAAAAAPAAPLPAAAAAPLLAATLAALGADVPAAAAPAAPAASPDAAPAAALPGAVEEAEDVDDEPPLDDDALADLDLPRPPPREDDPAP",
        "response#2": "SPSPSPSSSPSSSSSSPSSPSSPSSPSSPSSSSSSPSSSSSSPRRRRPPRPRPRRRRRRPPRPRPRLRHRRRPRPRLRDPRRPRPRRPRRPRRPRPPRPRRRRRPRPRRPRRPRPRRRRRPRRRPRPRRPPRRATPTATATATATPTAPTTATATPTATATPTAPATATTPTATATAPAPATPAATATATATATATTATATATATPATATPAATATATAAAAATAAAAATATAAAAAATAAAAATPTATPTATATTA",
        "response#3": "MSPARPAPAPARRPAPRPAPAPAPAPAAPAPAPRPPRHRRPRPAPRRRRRPAAPHPRAPRPRRAAAPAAAPPAAPAAAPAPAPAPAPAAAAPAAAAGARAARTALRRRRPPAPAPRAPRPRAPAPARRAAARRPVHDRRGHRHDDDDDDEDEEEEEEEEEDEDEGEEEQQQPHRSRHRHHHHHLHHHHHHRHHHHHHHHRHH"
    },
    {
        "reference": "MPARKYKIHVPCTSANIGPGFDVCGIALSLSLSLVVTIPSVSSGAEPLPKIIYTGLDSDNVPLSPYKNLLTRVALYVLRANGITTFPPGVTIEARNEIPFGRGLGSSGAAVIAGVLLGDLLGNLSLPKSRLLDFALMVERHPDNVTAALMGGFVGSYLRELSPEDMSAASIPLAEVLPEYPPDAGPDWGKSPPQPPHGIGHFVRFGWAKEIKAIAVSPRFELATAKARGVLPESYSRKDMIFNLQRLAVLTTALARSPPDPDLIYDAMGDRVHQPYRMTLIPGLPKILSTLTPTSHPGLLGICLSGAGPTILALATHNFEAIANEIERIFGDEQVLVDHKVLNIDEKGSWVEDITEA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Ribsml_uS5_D2-typ_fold_subgr, Ribosomal_Su5_D2-typ_SF sharing conserved structural features; 2. The protein must be able to perform the nucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005524",
                "GO-Name": "ATP binding "
            },
            {
                "GO-ID": "GO:0004413",
                "GO-Name": " homoserine kinase activity "
            }
        ],
        "go_f_mapped": [
            61
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR014721",
                "InterPro-Name": "Ribsml_uS5_D2-typ_fold_subgr",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 173
            },
            {
                "InterPro-ID": "IPR020568",
                "InterPro-Name": "Ribosomal_Su5_D2-typ_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 157
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014721",
                "InterPro-Name": "Ribsml_uS5_D2-typ_fold_subgr",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 173
            },
            {
                "InterPro-ID": "IPR006203",
                "InterPro-Name": "GHMP_knse_ATP-bd_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 98,
                "End": 109
            },
            {
                "InterPro-ID": "IPR036554",
                "InterPro-Name": "GHMP_kinase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 210,
                "End": 332
            },
            {
                "InterPro-ID": "IPR020568",
                "InterPro-Name": "Ribosomal_Su5_D2-typ_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 157
            },
            {
                "InterPro-ID": "IPR006204",
                "InterPro-Name": "GHMP_kinase_N_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 68,
                "End": 152
            },
            {
                "InterPro-ID": "IPR000870",
                "InterPro-Name": "Homoserine_kinase",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 354
            },
            {
                "InterPro-ID": "IPR013750",
                "InterPro-Name": "GHMP_kinase_C_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 259,
                "End": 326
            },
            {
                "InterPro-ID": "IPR000870",
                "InterPro-Name": "Homoserine_kinase",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 352
            },
            {
                "InterPro-ID": "IPR000870",
                "InterPro-Name": "Homoserine_kinase",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 352
            },
            {
                "InterPro-ID": "IPR036554",
                "InterPro-Name": "GHMP_kinase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 207,
                "End": 339
            }
        ],
        "ipr_mapped": [
            387,
            983
        ],
        "response#1": "MYKYYLYIKNKKYIYYLNKFIKNYKKNNIKINIFIKNNYIYININKIYILNYIIYNFISNNYIKNNKFKIIYNKKYIKIYYKNNNQLRIIIKKIKNKIKYINKKYIIYHNYNKYIININKYKYYLIYINKKNIYINYNIFYYYLNIYIKKYNIKYNIYKNIIKLYSNDKYILNKIIKIFNEKYFYIYNKKIKFNYNHKNYYNYKYYKYNNKYINIKYFNKILKYIIKKYNNYKYNINKNIIYIKSKNKYLLKKFILLIYNKYKLINLNNYKKYLINNKKIYKCKIYLNNIILNKTIYKINLYIKKYNKNNYIKYYIKKNKIILYSNNYFILNKIIYYLNKKKINTNKYFKYYK",
        "response#2": "MEYKYKIIYKENINKNKINNIFNYIKNKYKFKNIECNYKNNIIIIKDKDIYKINILKYEIKNYFKKENLNNIELKNYEIKNEYLQNIKFKEKINNINIKKFINYINKKENIEYKIHKDKEIKLLSKNKKNINKLINYIKNDIDIFFKSENINIEKEKYIQKIKFNEKIDNYLYKNINKYIKKNKININININNNNIEIYSKEIKYLKNIIYYIKNNIKNYNIEFKNFKK",
        "response#3": "MKINIYFSKNINFKKIFYNNILKKNKFIYLNNFFFFFKFFYKKNKLINFNIFEIKKNNKKKYNKIILFNNINFYFIFNKKYKKILINFNIFENNNIFNYIFINNIIKKNINFKIYINNNFFFIFNNIFINFFIKYKINKLNIKNNFIKIIKLNKKNKIFWNKIFITNYFFKKINIFIKNFNNFKYFIILIYKINFIININFNFYYKIKKIFFYKNNFFYKKIFNFNFKI"
    },
    {
        "reference": "MNDFVFSDIPDILKPMASVEFDDPLTKATGDVLNWTLWLIRNFPALSNIIMRLPSSLVSIVTSSFEGANQMFQVTTSTHNLYSASLPTHATKQIISKLVEHEKTHIGPKNKDCVVQRLLNAHRDSESKISIPTPDATVRSEAIGFTLAGTADPPNILALGTFMAARDPEMQEGLYKELRAVWPDLRSPVPSYNLLHQLPLLRGVVKESIRFTHGVATGPARLVGAGGARIGGYNVPAKASLAVVAAPSYFVHMDETVFSEPEKFEPRRWADNDYSKSLVAFSRGRRMCPAEQFHVEPYETTSVPRSEERG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cytochrome_P450_monoxygenase, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 117,
                "End": 293
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 88,
                "End": 293
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 297
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 198,
                "End": 214
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 252,
                "End": 270
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 89,
                "End": 292
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 117,
                "End": 293
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 88,
                "End": 293
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 297
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 198,
                "End": 214
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 252,
                "End": 270
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 89,
                "End": 292
            }
        ],
        "ipr_mapped": [
            18,
            21,
            22,
            31
        ],
        "response#1": "MQYFAFDVMGSMTFSRRFGFLEQGKDVHGVIDAIWEGMKKAAPVGQIPWLDRVWLRNPLTRLVSPSPRGKILGFSMGQVRERMEAERAGRSPAQPDMLSRFLAFKEKHDIPDWTLNGWAMSNIIAGSDTTAVVLRAVTYHLLRHPGTLARLRAELDAAAAEGRLSPLPTWEEVQRLPYLNACIEEGLRLHPPVGLPLERVVPAGGLTLGDTYIPEGTVVGVSHYVVTRSPTVFPDPDAFRPERWLEQPALRRASAPFSIGPRACLGKNLAYMEMRLVLAVLLLRYDLELVSPESKDWLSHTKTYLLWEKPPLMVRLTPRRPPAVGRA",
        "response#2": "MVAQLSSRVFLGLPLCRNEKWLKTTINYTVDVFTAAEELRHWPEALRPLVHWFKPSCRKLRKQLAEAREIITPVLEERRRMEKEALAKGTYEKPNDFLQWMMDVATAEHERNPDLLVHRQLVLSIAAIHTASMSMTHVMFDLCARPELIQPLREEIRSVLIEAEAEEKSTSDWGDSPPPPLARWKKTSLYKLQLMDSVLKESQRMNPPGLVTMHRMVMKDITLSDGTFLPKGTRISIPAYSMHRDPEIYEDPEKFDPYRFVRMREEPNKYQFVSTSPEHLGFGHGKHACPGRFFAANEMKIALCHILLKYDLKFPEGAGRPKNINIGEFVASDPTAKLLVKRREV",
        "response#3": "VPNTPLRRMKKARDEMHAMAMDIIRAKKAEVTKQRATPKAGYVKREDLLDVLLEAKDEDGNGLTDQQVRDEVPTFLVAGHETTSNALTWTLYLLSKHPEVQQKLREELRPIGPNPTNEELNQLPYLNAVINEGLRLYPPAPLGIPRITTEDTEIAGHFIPKGTKVFVSHYTIGRSERYWKDADSFKPERWLEDATNSGGAKSNYAFLTFLAGPRACIGKNFAMMEMKVTLATVLSRFDVELLDPSRDVTPESSITLHAKGGLPVRLKPVRTW"
    },
    {
        "reference": "MATDTAVTGAPETMQLRLASGNGPVTRTVLRTPLRDALPSEVPLIDISPIFSTSVADRKAVACKIHDAATNIGFFYIQNHRVPSRDTDMAYSASLDFFRQDMEAKMKADAKKGPFDSGYRGPGTQRVNPDEGADLRETYSILYDPMLDPTVPDPARIPEPASRFLHLGRAPFESTDTLPHFKDAFVRYFQACLALARALTRTFALSLDLPESAFDSKVQYPDASLEINFYPPISTGHAVSAPADPDTRVSIGSHTDFLLFTILWQDSNGGLQVLNREGQWIRASPVEGTFVVNIGDYLQRITNDKYVSTVHRAQNWSGRQRVSMPFFWGFGMHESCQVLESCCGEDGKSKYDEVRCVDWVSRRLGNLFDLSDKG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Oxoglu/Fe-dep_dioxygenase_dom that are essential for its biological function; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051213",
                "GO-Name": "dioxygenase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 220,
                "End": 330
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR027443",
                "InterPro-Name": "IPNS-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 36,
                "End": 370
            },
            {
                "InterPro-ID": "IPR026992",
                "InterPro-Name": "DIOX_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 149
            },
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 220,
                "End": 330
            },
            {
                "InterPro-ID": "IPR050231",
                "InterPro-Name": "Iron_ascorbate_oxido_reductase",
                "InterPro-Type": "FAMILY",
                "Beg": 42,
                "End": 333
            },
            {
                "InterPro-ID": "IPR044861",
                "InterPro-Name": "IPNS-like_FE2OG_OXY",
                "InterPro-Type": "DOMAIN",
                "Beg": 224,
                "End": 328
            }
        ],
        "ipr_mapped": [
            871
        ],
        "response#1": "MRVAVVGAGMAGLTAAVRLARRGHDVTVVEARARRLTDDAGAYYVCLPRPRLAGAGPLRAARLERALRLAAAEAGAVVRTGVRVTGVDPDAATLRLDDGTVLGDFDLVVGADGVGSAVRAAVDPDAPRPRYAGYVAWRGVAPRAALPPAVRDDAAVTEWWGPGVHVLAYPLDDDTVSFAAFAQVPADAGDDAAGDLALLRRRFAGWCDPVPRLLAAVPDAADVLHAPIHDVVAERWSAGRVVLLGDAAHATTPNLGQGACLALEDADVLADELDAHGVPAALAAYDAARRPRVRAVARASRRNLAMFQWRSPVALRLRDTGLRLAARTPPLRRAMLRRAVGEPPRPRRTPPPEAP",
        "response#2": "MNSYFKNNKNKNNKKNKKNKNNKKKKNKKNNKKNNNNKYNKYDEYDEYDEYDKCDKYDECDEYDEYDKYDEYDEYDKYDEYDEYDEYDKCDKCDKCDKCDKCDKYDKYDKSKSSKSSKSNKSSKSSKSSKSSNSNNIKSSKSNNIKSSNSNNIKSSKSNNIKSSKSNKSNKSNNIISNKSNNNNYNKSHNNNKYDNNNNIIL",
        "response#3": "MGPPIRHPRPRPRPRCRPPGRGGHAGRGAHVGRGAHVGGAHVRGAHVRGAHVRGAHVGGAHVGGAHVRGAHVRGPHPGAAPARVPAPRARHAAAPHPGAPHLHRAPAPQARRAAAPPAAPASGPRQRPAAARPGPRAPARPRLPGLPGPARPRPPPAPPASRPARPPAGAGRAPAPRPRRRPGRRARRPAPSRRRAAPARARPAGAVPRRRAGAAPRGRPGAPRAGRGAP"
    },
    {
        "reference": "MLSIDHVDWLELIRVTLHPLAKFPGPKLAGASYCYEFWYEVICGIQYTQKIIKLHEQYGPIVRINPDELHFNDVDFVDVVYTAGARKRDKSSHYLAGFGGVSKSTFGTLDHMHHRTRRRALNKFFSKSRVLQIEDSIHEKSQQLCDKFLAYRDQGPFDLTGAFSCIATDTVTEYCFGSSPGFLNQDGWEPNCKSYFETIERMAHVTRHVPWILYLAKWLPLSIIRLVSSDLNSFLVDTRVKKPERLKRVVLDAERHDAKDCPVFLELLNSDLPPREKSKQRFMYEANGATLAGSGSTAIAMSNIVYNLVANPRIGHKLRSELLGKVSDPKNLPRWSSLEELPYLTAVIHEGLRSMYDPSKERLPYDPSQERLPRIATEEELIYKDGSTPGKSKYVIPRGYAIGTSAHVVHSDESIFPNASQFNPERWLGRDGQRNRELERHLLSFSKGSRYCLGMHCRCTTCLALPASVRNGTRGY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cytochrome_P450_monoxygenase, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 47,
                "End": 456
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 460
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 456
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 456
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 445,
                "End": 454
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 410,
                "End": 428
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 341,
                "End": 357
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 436,
                "End": 452
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 47,
                "End": 456
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 460
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 456
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 456
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 445,
                "End": 454
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 410,
                "End": 428
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 341,
                "End": 357
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 436,
                "End": 452
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22,
            31
        ],
        "response#1": "MVLSVAAIHTTSDLLTQVIFDLCARPELIQPLREEIVSVLGDGWKKTALYNLKLMDSVLKESQRLKPPAQVSMRRFVKKDGITLSDGTFIPKGTKVAVAAYKMWDPEIYPDPEKFDGYRFVKMREVPGKENTAQFASTSPDHMGFGHGKHACPGRFFAANEVKIALCHILLKYDFELKDGRPEAVNSGIFLMADPSAKIMVKRR",
        "response#2": "MILNSKNVPEEEKSLERLRHEASTLIIAGSETTATTLSAATYYILRNPKVLHKLQEELRSAFPDFTSEITSHTVSSLPYLNAVIEETLRIYPPAPLGLPRIVPKGGDTIAGKWIPEQTVVSVAQYAAYHSEKNFVRPHEFLPERWLDRPELVDDRSAAQPFSIGPRNCIGKNLAYMEMRLTLARLLWNFDLELCEESKDWMTKQKVYLLWDKPELMVKLTPVERK",
        "response#3": "MGVPEWLRPIVARFLPKARKLVAEARAMIEPVLAERRRQKEEALANGTEPRYNDTIEWFEEAAQGRPYDPALAQLTLSLAAIHTTSDLLTQVLFDLCARPELIQPLREEIVSVIREHGGWKKTALYKLKLMDSVLKESQRLKPPVLLTMRRMAKQDVTLSDGTFIPKGTNIAVSTHAMWDPDVYPDPEKFDGYRFVKMREVPGNENSAQFVSTSPDHLGFGLGKHACPGRFFAANEVKVALCHILLKYDLKLVDDAPKPVYSGMFMAANPSARIMVRRR"
    },
    {
        "reference": "MGSNITSTSIIFLLTGVPGLEAFHTWISIPFCFLSVTALLGNSLILFATITQPSLHEPMYYFLSMLSATDLGLSISTLVTMLSIFWFNVREISFNACLSHMFFIKFFTVMESSVLLAMAFDRFVAVSNPLRYAMILTDSRIAQIGVASVIRGLLMLTPMVALLIRLSYCHSQVLHHSYCYHPDVMKLSCTDTRINSAVGLTAMFSTVGVDLLLILLSYVLIIRTVLSVASPEERKETFSTCVSHIVAFAIYYIPLISLSIVHRFGKQAPAYVHTMIANTYLLISPLMNPVIYSVKTKQIRRAVIKILHSKET",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to GPCR_Rhodpsn, GPCR_Rhodpsn, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity,olfactory receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            },
            {
                "GO-ID": "GO:0004984",
                "GO-Name": "olfactory receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            },
            {
                "GO-ID": "GO:0004984",
                "GO-Name": " olfactory receptor activity "
            }
        ],
        "go_f_mapped": [
            0,
            1
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 110,
                "End": 126
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 307
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 129,
                "End": 141
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 236,
                "End": 245
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 285,
                "End": 296
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 176,
                "End": 192
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 31,
                "End": 310
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 292
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 199,
                "End": 222
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 104,
                "End": 126
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 50
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 274,
                "End": 300
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 59,
                "End": 80
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050402",
                "InterPro-Name": "OR51/52/56-like",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 308
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 110,
                "End": 126
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 307
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 129,
                "End": 141
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 236,
                "End": 245
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 285,
                "End": 296
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 176,
                "End": 192
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 31,
                "End": 310
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 292
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 199,
                "End": 222
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 104,
                "End": 126
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 50
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 274,
                "End": 300
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 59,
                "End": 80
            }
        ],
        "ipr_mapped": [
            0,
            1,
            2
        ],
        "response#1": "MAEGNHTAVTEFILLGLSDRPEQQQILFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFVDICYSSVTTPKMLVNIQSENKTISYLGCLTQLYFFLAFGTTECFLLAVMAYDRYVAICNPLLYSVKMSTGVCVQLAAGSWVGGSVHALIHTLLTSRLSFCNSNKIDHYTCETVFFFSSDNSRINHYFCDISPLLKLSCSDTSVNEVVISSMVGSIVMVTVSVILISYVYIVSTILKMRSTEGRHKAFSTCTSHLTVVTLFYGTIIFTYVMPKSYYTTDQDKVVSVFYTVVTPMLNPFIYSLRNNDMKGALKRQLGRKIFSSK",
        "response#2": "DFFYTSTITPKMLVNFLSERNTISYLGCLTQLYFFHFFGGTECFLLAVMAYDRFVAICNPLLYSVNMNPQVCVLLVAGSYVGGFFNASIHTLLTFSLSFCGPNEVNHFFCDIPPLLKLSCSDTHVNELMIFFVCGSITMVTVLVILISYIFIVSTILKIRSTEGRHKAFSTCTSHLTAVTLFYGTIIFTYVMPKSYHTSDQDKMVSVFYTVVTPMLNPFIYSLRNKDMKGALKRLLGKIS",
        "response#3": "MAPENHTAVTEFILLGLSDRPELQPILFGLFLSMYLVTVLGNLLIILATISDSSLHTPMYFFLSNLSFLDICYSSVTTPKMLVNIQVERKTISYLGCATQLYFFLFFGDLECFLLAVMAYDRYVAICNPLLYSVIMSPQVCVLLVGGSYVGGSVNALVHTLLTFRLSFCGSNEINHFFCDIPALLKLSCSSTHVNELVIFVSVGSITMVTVLVIAISYTYIVSTILKIRSTEGKHKAFSTCASHLTVVTLFYGTIIFTYVRPKSSYSTDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRLLTKSKIRSTEGKHKAFSTCASHLTVVTLFYGTIIFTYVRPKSSYSTDQDKVVSVFYTVVTPMLNPFIFSLRNKDVKGALKRLLTKS"
    },
    {
        "reference": "MKFLCLHGAYGNIPAFRVQLGPMIDALEFDGSASFEFIQGRVSVVPPPGFESYFGPAPHYRFLKDRGEAEASAVEGIRVFPEAETPEDALRALMPRDDMEIGFADARGLALEQLYEALDADPEISGIIGYSEGASAAATLVYDEQERMRSEGYVPRIKAAIFFMGWPALTAENVPALSDEVENLLEVPSLHIVGANDPYKDGALALYNIFDDNMAVFFDSAGGHTIPRHGKLLQELVSAVKDLIADVPEDNSADLLAPAVTGKRLDSAVDIPNLSFLKNEDA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 247
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 243
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 247
            },
            {
                "InterPro-ID": "IPR005645",
                "InterPro-Name": "FSH-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2,
                "End": 232
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 243
            },
            {
                "InterPro-ID": "IPR050593",
                "InterPro-Name": "LovG",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 244
            }
        ],
        "ipr_mapped": [
            35
        ],
        "response#1": "MKTTRLLLLAALAAPLAAHAQTPAPAAPAAAAAPAAPAAPAPAGKFVEANGVKLFVRQLGEGPDVVLLHGFGTDSSAWDAVAPALAKTHRVTLIDLPGFGKSDAPKDRKYDFDGYVDDLVGVLDALKVPKATFVGHSVSAMIGLLAAIKRPDLFANLVLVGASPRYLNDDDYHGGFEQEDIDEVFGAMEANYAGWSAYFAPVAVGNANPEAVKLFSDKLFAMRPDIALSVARTVFLSDLRAELPKVTVPTTILQVTQDLAVPVSVSRYLHDHIAGSKLVEIKGTGHVPHLSAPAETVAAIEAAIAAAPKK",
        "response#2": "MPRARRRRRRRRRSRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRSRRRRRRRRRRRRRRRRRRRRRTGTRRRSRTGTGTRTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGRRRVDVPGARLNVRVLGDGPETVVLAHGLGTDQSAWSLVAPSLAERHRVVLYDLVGPGLSDAPTDPARYTLDGHVDDLVGVLDALGIGRCHLVGHSVSAMIGVLAAVRRPDLFASLTLVGASPRYLNDDDYHGGFEQEDIDELFGAMEANHAGWSAGFAPVAVGTDDAPRAVEEFSRSFLRMRPDIALSVARTVFLSDHRADLGKVTAPTTVLQVTGDAAVPLAVGRYLRDHIPGARLVEIEARGHLPHLSAPAETAAAIETTIREGAR",
        "response#3": "MRRSPRLACASVLAALAALAAACASRPRPVPAPPPPPPPARPEPAPPPPPPAAPPPPPSPPPAPPPPPPPPPPPEGRYVETKHGKIFVREMGKGVPLVFIHGFGGSSFIWRYNFDYFSKTHRVVAIDLLGFGKSDKPLDPKLYTLENFVEQLEEVRQALKLEKFYLVGHSLGGVLAIDYTLRHPERVAGLVLVNTTARWPRPPRTEAQEKAAREALKSLQIERRPEALQRFVQQPPPPNLLDMVKTEEALEAIARFVFAPGRVDPEFVREYARQQSETRPEVTAASLGALFVEDKTDLLPKVKVPTLIIAGERDKLTPPWMSERMHELIPNSRLVIIKDAGHMPMLEKPEEFNKVLEEFLREVEKK"
    },
    {
        "reference": "MVKPTKSNIGVYTNPAHDLWVAEAEPSLEQVQTGEKLAPGEVTVAVKSTGICGSDVHFWHAGCIGPMIVEDDHILGHESAGVVVAVHENVKSLKVGDRVAIEPNIICGECEPCLTGRYNGCDSVLFRSTPPVPGLLRRYVNHPAMWCHKIGDMSYENGSLLEPLSVALAGVQRAEVRLGDPILVCGAGPIGLVTLACVKAAGAEPIIITDIDEGRLAFAKEFCPSVRTHKVDFKHTPEDFAKAITELGGGVEPAIALECTGVESSIAGAIQTVKFGGKVFVIGVGKNEIKIPFMRLSTREVDLQFQYRYANTWPRAIRLLQGGVINLEKLVTHRFKIEDALEAFKTAADPKTGAIKVQIQSFEEGESR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity,cation binding,nucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003939",
                "GO-Name": "L-iditol 2-dehydrogenase (NAD+) activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": " nucleotide binding "
            }
        ],
        "go_f_mapped": [
            4,
            183,
            61
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 322
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 322
            },
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 189,
                "End": 321
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 151
            },
            {
                "InterPro-ID": "IPR045306",
                "InterPro-Name": "SDH-like",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 360
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 187
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MPRVRRALVTGASGFLGRHLLEELRRRGYEVWALDLAPPRGPLPEGVRYVRGDVADPEAVRRALEEAGPADLVFHLAALTPPPEPRRPLEERLERYLRVNAEGTANVLRAAREAGVRRVVVTSSAAVYGRPWRRPGEPVEESRRPRPGDPYQASKALAEARALEAAREGLEVVVLRPSLVYGPGAVLLERLVRLAEEGRLPAYVGDGRHRVHLVHAEDVARALILAAEREGARGVYHLVGREAYTLAELLEALREELGLRARPTRLPRPLVRALAPLVRPLRPLAPRLEPLLRGTLEELEALLPYLLEDRVFSVERARELGLEPRPLEDTREAVRRWLEERRRRGRR",
        "response#2": "MKKNKRKEKMEKLKKILITGASGFIGSHTTKLLLEKEYEVHALVRNVEKTRKVFEEVLGKENLKKLHIHEGDITDKESLEKVMKDVDGVIHLAAYVPSRDFEKVLKVNVEGLRNVLEVCRKEKVKKLVLASSGAVYGLTEEELKDVKEDTKVKLDWENIGHPYAASKYAGELLALEYGKKYELPITILRYFNVYGPRDTTTTRLLLNILKGKQKIVENQKRSFIYVKDAAEANLKVLEKGEEKGEKIQVFNLGGPEVHSIKEIAEKVKELTGKEVEIEVKEEEKEKEKRLYSVEKAEKELGYKFRPLEEGLKETLEWLKKEHPEILKEEKK",
        "response#3": "MINNNIQEDEIENIDENIDKKNKKNENIKDEKNNENIEKDENIDENKNENINEKDDKNIEENENIKNIDEDNNIEEENKEEEDENKFKNFEKENNIDKDENIKIDEIKEEDENIKNEFKKVEENESENKEDFLNNSEEIKEEEKEIKENKNNNKKENNEKNEKIKNDSKNKKNNEETKENIENKELEENKKKTKKNSFFSFFFNFFRKK"
    },
    {
        "reference": "MRSVSPQSTMARIPERRVRTLDFAQFRHGEPSGSRGFCRELVDCLSSVGFVKIRNHGISGQEIENVFVMSQLFFSLPQAAKGKAAHPPEANPHRGYSYVGQEKLSRVKDYEKGKREITDVYDIKHYPIDRDARQESYDQGAAVDNLYPNRWPDEQDIPGFRVLMETFYERCHEVHQDILRAIAIGFDLSPSFLTDLCCQNTSELRLNHYPSVHPSSLRKGAKRISEHTDFGTVTLLFQDSVGGLEIEDQNTPGTYFPVLSERKSDIIVNIGDCIQRWTNDKIHSTSHRVVLPEDTDALTKDRYSVAYFGKPSRSQLVGSLREFVKEGEKPKYNDISAWQYNQEKLVLTY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Oxoglu/Fe-dep_dioxygenase_dom that are essential for its biological function; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051213",
                "GO-Name": "dioxygenase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 200,
                "End": 311
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR026992",
                "InterPro-Name": "DIOX_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 154
            },
            {
                "InterPro-ID": "IPR044861",
                "InterPro-Name": "IPNS-like_FE2OG_OXY",
                "InterPro-Type": "DOMAIN",
                "Beg": 204,
                "End": 309
            },
            {
                "InterPro-ID": "IPR050231",
                "InterPro-Name": "Iron_ascorbate_oxido_reductase",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 340
            },
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 200,
                "End": 311
            },
            {
                "InterPro-ID": "IPR027443",
                "InterPro-Name": "IPNS-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 349
            }
        ],
        "ipr_mapped": [
            871
        ],
        "response#1": "QQQQQQQQQQQQQQQQQQQQQQQQQQQNNSNSNNSNSNNSNSNNSNSNNSNSNSNNSNSNNSNSNNSNSNNSNSNNSNSNNSNSNNSNSNSNNSNSNNSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEKEKKEKKEKKEKKEKKEKKEKEEKEEKEEKEEKEEKEKEEKEEKEEKEEKEEKEEKEEKEEKEEKEKEEKEEKEEKEEKEEKEEKEEKEEKEKEKEKEKEKEKEKEKVKEKEKEKEKEKEKEKESSSSSSSSSSSSSSSSSSSSSSSSSSSS",
        "response#2": "MKKKNKIIKINKKKKEKNVLKNEYTLKNVELKSQKSYSGKKNIEETNKTNETNKTKVISKVKENNKIKEIKIKKINENINNNENEITKINKNNIKKNNINKNKHVKNNNKENIKKNYIKNIKKNIKKNINKKNEKKNINKNYKNNKKSINFNIKNINNKKDNKKINKNSNEEINNIIRKKKINYDKDLMINNITNNIIENELKIINDILNNNKKIKNVFKEIKKNKNIIKLKNINKNFKIINNNINEEKKKTITKENILEKKYNSKEKKKNNKDKDNDKDDDDDDDNDDDDDDDDDDDDNDDNNSSGSSSDNDSDSNNDINDDDDDDDDDDSDFDNNSDFDSDSSSNFDSDFDSDSDSDSDSDSRSDSDSDSDKYY",
        "response#3": "MIFFFKKKILLIYIFSFNNNYYKFFFDYKIKKNIFFIKKKYKNFQNFFFLNLIFKINLKINNILFINNNIIYNEKIIKNNFNIKIIYINFKKILLIKKNNNKLFFFFKKIIYKNLIINFFFKKDFKWKNLIFINFNFKNIIFINKIKKFFIFNKINIIIINIIFYLFFFNIFKKNIFKIIINNKNIIKNILNFFFIYKINNNLFFFFFFYFFYFKIFLKKKNKKININNNNIFFKKKKNKIKILFIKKKFFLNYYYNKKFILNYFLNFLNINFNLNFKIIFYNFIFFKYIKKNKKKKKINIFINKIFIKIFFIKNNIKFFKNNFINKNYFYLNKKIFFKYYKIFNIIKKKKIFFNFNNI"
    },
    {
        "reference": "MEKEKGEEKMNDSRKITVIGLGYVGLPLAIHFAERGYNVVGLDKDKRKIERIEKGDSYIPDVSSNVLKDLVQNKQLVVYTPHTGIEEFQNSEYVIVTVPTPINKQKEPDLSALIAASHYIKQNLQAGQTFIFESSTYPGTLEEVIIPIIAQSGKEVGKDYYIGYSPERIDPANQQYTVQTIPKVISGQTERCKQQVQKLYSTIFDTVVPVSSPKVAEMCKLFENIQRLVNISLVNELNILCEKLGIDFREALEAAATKPFGFTPYWPGPGIGGHCIPVDPLYFQWKARQLGQSSQLIEVAHMINEKMPQQIVTQVKELSAPPGTVFLIGIAYKKDVNDLRESPALPIIELLVNEGYKVQYHDPYISSAKIGDKIYDSIPLKKKTLEKADCILIVTDHSNIDWNICKGMKHVIDTRGVLKKVSA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within 6-PGluconate_DH-like_C_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the NAD binding,oxidoreductase activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding "
            },
            {
                "GO-ID": "GO:0016628",
                "GO-Name": " oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor "
            },
            {
                "GO-ID": "GO:0003979",
                "GO-Name": " UDP-glucose 6-dehydrogenase activity "
            }
        ],
        "go_f_mapped": [
            22,
            4,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 214,
                "End": 307
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 208
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR028359",
                "InterPro-Name": "UDP_ManNAc/GlcNAc_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 423
            },
            {
                "InterPro-ID": "IPR014027",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 326,
                "End": 420
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 214,
                "End": 307
            },
            {
                "InterPro-ID": "IPR017476",
                "InterPro-Name": "UDP-Glc/GDP-Man",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 421
            },
            {
                "InterPro-ID": "IPR014026",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_dimer",
                "InterPro-Type": "DOMAIN",
                "Beg": 215,
                "End": 305
            },
            {
                "InterPro-ID": "IPR028359",
                "InterPro-Name": "UDP_ManNAc/GlcNAc_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 421
            },
            {
                "InterPro-ID": "IPR014027",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 327,
                "End": 419
            },
            {
                "InterPro-ID": "IPR017476",
                "InterPro-Name": "UDP-Glc/GDP-Man",
                "InterPro-Type": "FAMILY",
                "Beg": 15,
                "End": 415
            },
            {
                "InterPro-ID": "IPR036220",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 321,
                "End": 419
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 208
            },
            {
                "InterPro-ID": "IPR001732",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 196
            }
        ],
        "ipr_mapped": [
            7,
            503
        ],
        "response#1": "MTSPSTPPPEAPAATAPSVTATPPKASPAAAEPGAEPDAAAAAADDELAGRVAFVTGGASGLGEATARLFAARGARVVVADLDEERGRRVAEEVGGRFVRLDVTDEDSVRAAVRTAVESFGRLDCAFNNAGIEGPSAPLEETTEEEWDRVMAVNLRGVLLGMRAELRAMRAAGGGSVVNTASVAGLVGAPGMSAYTASKHGVVGLTKAAALEYARDGVRVNAICPGYVDTPMLDAVLAASAPGRPREEVFAEMAAAQPLRRMLTPEEVAEAALFLASPRASAVTGVVLPVDGGLTAAPVPPAPPPTTPPTTPPTTPPATPPTTPAAEPAAEPAPEPAAEPAVGPADPPDGGRTARRRVP",
        "response#2": "MAVERWLEGRVALVTGAARGIGAAIARALAERGAAVVLNYHRSEEAARRVAEEIAREHGGRAVFVRADVSREEEVERLMEAAREAFGRLDILVNNAGIMGPQRPLHEVRVEEFDRVIAVNLRGPFLLARAAIPLMLERGGGVIVNISSIAGLMGNYVAHYVASKHGLVGLTKALAVEYGPRGVRVVAVCPGFIDTDITRPEVWARLRRAGPEEGPGVTREEVRRRLEASVPLRRVGTPEEIARVVAFLASPEASYVTGVCYPVDGGWTAYHIWPPAA",
        "response#3": "MASKVAIITGATSGIGLATAKLFSQNGYKVAITGRSADRLEATKKEITDAGSPDVLTVPGDVTKKEDAEKIFADTVKAFGKLDVIVNNAGANIAFKPLLETTEEDFDKMMSLNLKGSFFVMQAAAPHLNDGGSIVNISSIASHIAGVPGISLYSTSKAGLDGLTRSAAAELGPRKITVNSISPGFVETPMTAGAAAAIGMDKDEMAKKAGGELFSVE"
    },
    {
        "reference": "MSDLANTAERRGEKRPAGGNRRGNRLPRDERRGQLLIAASEVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVSGVRQALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQVAAQVKVATEACTDAVFDLISRDSGLEAHRARMIAVGLVAISVDSARYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Homeodomain-like_sf sharing conserved structural features; 2. The protein must be able to perform the DNA-binding transcription factor activity,transcription cis-regulatory region binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity "
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": " transcription cis-regulatory region binding "
            }
        ],
        "go_f_mapped": [
            160,
            91
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 107
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 107
            },
            {
                "InterPro-ID": "IPR050109",
                "InterPro-Name": "HTH-type_TetR-like_transc_reg",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 215
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 29,
                "End": 89
            },
            {
                "InterPro-ID": "IPR054129",
                "InterPro-Name": "DesT_TetR_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 104,
                "End": 209
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 35,
                "End": 48
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 56,
                "End": 79
            },
            {
                "InterPro-ID": "IPR036271",
                "InterPro-Name": "Tet_transcr_reg_TetR-rel_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 213
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 81
            }
        ],
        "ipr_mapped": [
            408
        ],
        "response#1": "MFRGTHHLRLDAKGRLALPARHRDALLAHCTGRLVLTRDLHHPCLLLYPLPEWERLERTLAAHPDPLTRLLLGHAVDLELDAQGRLLLPPELRDHAGLRRELLLGQALRLELWDQARWEAHLRRLPALLAPAPAPAPAQAPAPARAPAPTPSPAPAPAPAPAQAQEQAPAQAPTPSPAQAPAPAPAPAPTPSPAQAPSPAQAPTPSPAQAPSPAQAQEPAPAPAQAPSPAQAQEQAPAPTPSPAQAPTPSPAQVPAPSPAQEQAPAPAPAPAPARALPRRPRAAPRDRLQRRLARTLRERRRQRPAPAARLRPPRPRPHATPPGPPRAHRARRTTPAPQR",
        "response#2": "MFRGATLVNLDSKGRLTVPTRYREQLIESATGQMVCTIDIHPCLLLYPLPEWEIIEQQLSRLPSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKADIEASQGETLSDRLTQLLSGETPATSAPAAAVPEPSRPGAPLPAPAAPALQPARPVSVAAGPGPVAAERPFAAAPAESAAPAAAPVFAATPINGLGQPLAGAEARSVVRRFLSGASQVNMDSKGRLIVPTRLREQLGSGQLVLTKGLDNCLFGYPLPEWEILEQKLSQLSSMNPAARRVQRFLLGHASECEMDGAGRLLIAPVLRQHAGLTKEVVLVGQSNRFELWDETTWYQQVAEDIAADQFDF",
        "response#3": "MLFRGATLVNLDSKGRLTVPTRLREQLGLEAEGQMVCTIDQLHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDKAGRLLIPPRLREHLGLEAEGQMVCTIDQLHPGQMVCTIDQLHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDKAGRLLIPPRLRQHAGLTKEMVLVGQFNRFEIWDETRWYQQVKESSDAFSQLAQDLSL"
    },
    {
        "reference": "KEGYIVNLSTGCKYECYKLGDNDYCLKECKLQYGKGAGGYCYAFGCWCTHLYEQAVVWPLPKKTCN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more LCN-type_CS_alpha_beta_dom, Scorpion_toxin-like that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            }
        ],
        "ipr_mapped": [
            64,
            61,
            62,
            63
        ],
        "response#1": "MNSLLMITACLVLIGTVWAKEGYLVNSSTGCKYTCFKLGDNEYCDRECKAKGASYGYCYAFGCWCEGLPDWVKTWDRATNTCGGKGKVYDIIRKDGRDGYIRGRDGCKVSCLWGNEGCDRECKANGASYGYCWTWGLACWCEGLPDDKTWKYETNTCAGKGRTTASRRVVAVEKKGALGEQRNPSKQQDREMNRTIITGGTENKDAQGSGKKRTGEAAKKSEPETRKDGYIAPDGCKYECFFGNNSYCNDECTKKHKADYGYWAAFGCWCTNLPDNVKTWERETNTCKGRKRKSIQSWYEDFIERNIKMDYYILLIATASMLIESVNARDGYIRGRDGCKVSCLWGNEGCDRECKAAGASYGYCWTWGLACWCEGLPDDKTWKYETNTCGGKK",
        "response#2": "MNSLLMITACLALIGTVWAKEGYLVNYYTGCKYECLKKLGDNDYCLRECKARYGKGAGGYCYAFGCWCTHLYEQAVVWPLKDKSCNVKDKSKKSREGKDYYVDLYTKTKYECLKLGENEYCNKECKRYYSRSSYCQVVDLKESKYPWDDEASKYVIDFVRDLHEVLQKFLDFYARQDSLIFESYEKYPGVTYKSLDGIMKYRTTEEKMLIPTEIVKEVADKGDMVCKIRTKNVENYYCEEKYLNGKKQTNCLVKLKPVGSKAREEKIVKKAKKEKMNSLLMITACLALIGTVWAKEGYLVNRSTGCKYECFKLGDNDYCDRECKALGGSYGYCWTWGFACWCEGLPDDKTWKSETNTCGKKK",
        "response#3": "MNSLLMITACLVLIGTVWAKEGYLVNKSTGCKYECFKLGDNDYCLRECKAYGASYGYCYAFGCWCEHLYEQAVVWPLPKKSCGRKCYTVVPADKTYNVAIDGSHVVSSYYGNADYVIEIAEKYVGYWNGGVTFANDGKKRIHFFAKSQNSFSVLLLSNQSKKKKASASVKIPCLSSSLTSAGSFLKLLVISYVSWKPIVLVESNRDGYIAKPEGCKYSCLWGNEGCDRECKQRYGKGAGGYCYAFGCWCTHLYEQAVVWPLPNKTCNGK"
    },
    {
        "reference": "KEGYIVNHSTGCKYECYKLGDNDYCLRECKLQYGKGAGGYCYAFGCWCTHLYEQAVVWPLPKKTCN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Scorpion_toxin-like, LCN-type_CS_alpha_beta_dom that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            }
        ],
        "ipr_mapped": [
            64,
            61,
            62,
            63
        ],
        "response#1": "MNSLLMITACLVLFGTVWSARDGYIRGSDGCKVSCLWGNEGCDRECKAVGGSYGYCWTWGLACWCEGLPDDKTWKYETNTCGSKGKSLVAPSGEKDGYPLDSDNCKYSCYKLGENEYCDKECKAKGASSGYCYGFACYCYYMKEWTKTKERSAGKEKKKASHVTKNAGCEGVSPAYTKMYAAVERLNEYKSRKEKVVGTDGFGGDRFYVTDYNLMYTRKDEDVGDDFINVLNFYYDGCVMIGVESARDGYIRGRDGCKVSCLWGNEGCDRECKAYGGSYGYCWTWGLACWCEGLPDDKTWKSETNRCGGKK",
        "response#2": "MNSLLMITACLALIGTVWAKEGYLVNYYTGCKYECYKLGDNDYCLRECKQRYGKGAGGYCYAFGCWCTHLYEQAVVWPLKDKTCTYPLRVGGKPPDARQAVYIGYERLSPHDWGTPRQATSERKELRVEPNGEETDLSRETNMNYLLVITACLALIGVVWAKEGYLVNYYTGCKYECYKLGDNDYCLRECKQKGAKSGYCYAFGCWCTHLYEQAVVWPLKDKTCTYPLRSSRDAYIAKPEGCKYECLWDNDYCLRECKQRYGKGAGGYCYAFGCWCTHLYEQAVVWPLKDKTCTGK",
        "response#3": "MNSLLMITACLALIGTVWAKEGYLVNYHTGCKYECFKLGENDYCLRECKQQYGKGAGGYCYAFGCWCTHLYEQAVVWPLKNKSCTGKKKGRGRYLFNDKEIWVVSDDLVKLHVIPYPSTSIGKEWDETTTNADRVTHDYFLLDIEKDNTYYTYYNKDTYYTWVRNDGCNTRNTKIKLNANNEFSASWSSEDKSSEEDLFSTFADKYQESRREIHIIPIGYREKFGKKYEYDDYYGKGGALKCEEACYCSYDKRLVELKEKEETVFATNDKRLLRLLENYTVAIILSGQRNGDVMDTEDETNMNSLLMITACLVLIGTVWAKEGYLVNKSTGCKYECFKLGENDYCDRECKARGASYGYCYTWGFACWCEGLPDSTPVWKSETNTCGKR"
    },
    {
        "reference": "KEGYIVNYYDGCKYACVKLGDNDYCLRECRLRYYKSAGGYCYAFACWCTHLYEQAVVWPLPNKTCN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more LCN-type_CS_alpha_beta_dom, Scorpion_toxin-like that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            }
        ],
        "ipr_mapped": [
            64,
            61,
            62,
            63
        ],
        "response#1": "MNSLLMITACLALIGTVWAKEGYLVNYYTGCKYECFKLGDNDYCLRECKARYGKGAGGYCYAFGCWCTHLYEQAVVWPLPNKSCNQQGVTVTTWTSTINIDLAERDNPTKPCDRFQVNGEINTRNLDQHGNCDVAITERSYLKNDSMMWKNCNIWDSHGSKYKHDYQDTGKVDVDPLGDPFTKGRLSKHEVEWLCQLAVKFVEKKVARPLRLKVETMNSLVFISALLLIGTGVESRDGYIRGSDGCKVSCLIGNEGCDKECKAYGGSYGYCWTWGLACWCEGLPDDRTWKYETNTCGGKK",
        "response#2": "MNSLLMITACLVLIGTVWAKEGYLVNKSTGCKYECFKLGENEYCDRECKAYGASYGYCYAFGCWCEHLYEQAVVWPLPNKTCSTPGKTVAIVIESNRDGYIRGRDGCKVSCLWGNEGCDRECKAFGGSYGYCWTWGLACWCEGLPDDKTWKSETKTCGGKGIRVAEQELIGSYVAAGVNIGGADDEGFGGVWEIERGEKGKWCSTEVDEKKGHIREFQSDALCYYIFLAEEKPGYEVWVKGKVEPGWNPAVVDTKLYWVLKYTGSQSSANASDVSPPSKSESAGENRDGYIRGRDGCKVSCLWGNEGCDRECKAYGGSYGYCWTWGLACWCEGLPDDKETWKSETNTCGRK",
        "response#3": "MNSLLMITACLALLAITGVESARDGYIRGSDGCKVSCLWGNEGCDKECKANGASYGYCWTWGLACWCEGLPDDKTWKSETNTCGGKGVSLLFFNVHLDEKKTDEGLQKLDTIGGCNRPSMSWTNGKGEEREVYSFSGRESGDVAKKDDWAYEKMLNYLTLIALALLAITGVESARDGYIRGSDGCKVSCLWGNEGCDKECKAVGGSYGYCWTWGLACWCEGLPDDKTWKSETNTCGGKK"
    },
    {
        "reference": "KEGYIVNYHDGCKYACVKLGDNDYCLRECRLRYYKSAGGYCYAFACWCTHLYEQAVVWPLPNKTCN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more LCN-type_CS_alpha_beta_dom, Scorpion_toxin-like that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            }
        ],
        "ipr_mapped": [
            64,
            61,
            62,
            63
        ],
        "response#1": "MNSLLMITACLVLIGTVWAKEGYLVNYYTGCKYECFKLFGKNDYCDRECKAYGASYGYCYAFACWCEHLYEQAVVWPLPKKSCNYKAEPMIDVYEDGGFLLHRQFGNSISWYVGIQPIEKLRDAFEGNKYNVEQMNNVLANLGVVVILDAILKKLKTNMNSLLMITACLVLIGTVWAKEGYLVNKSTGCKYSCFKLGDNEYCDRECKALGASYGYCWTWGLACWCEGLPDDRTWKSETNTCGGKK",
        "response#2": "MNSLVMITACLALIGTVWSVKDGYIADNEGCKVSCLWGNEGCNRECKARYGQSYGYCYAFGCWCTHLYEQAVVWPLPNKSCSYKKGSKGDYPLVIGGDACDKDYYLVGNDGCKYSCFFPSSNYYDKECKKHGYKDGYCYWFECWCTGLEDDRKVTTFLPGSWIAKLVLDSLKCLLKETLELSHDGLSGSEANVHVTRAQTSSTPHGSLPGDQSTTFMNCLFLLTLVSSALLLITGAESRDGYIRGHDGCKVSCLWGNEGCDRECKALGGSYGYCWTWGLACWCEGLPDDRTWKYETNTCGGKK",
        "response#3": "KNSLLMITACLALIGTVWAKEGYLVNYHTGCKYECWKLGDNDYCLRECKARYGKGAGGYCYAFGCWCTHLYEQAVVWPLKDKSCYDKLGSGEFCLQMVSLDPDNAGKTASINDTLQQSKRNKGRKTGPALANSSVSPSRSSRAIRKRGRRYTRPDYHYAKQQTIDRNVKMNSLLMITACLALIGTVWAKEGYLVNQSTGCKYECLKLGDNDYCLRECKKYGASYGYCYAFACWCEHLYEQAKVWVRETNTCGKK"
    },
    {
        "reference": "MSVPPPGATPSRTSRTKGLKDRPRMENEEKLVEYLKRATTDLRQARRRLREVEDQQQEPVAIIGMSCRYPGDVHSPDDLWRMVADGDDGISTFPAERGWDVERLYDPDPDRPGTTYTTRGGFLHDAHLFDAEFFGISPREALATDPQQRLLLETSWEAFERAGIDPTSLRGSHTGVFAGVMYQDYAHRVRPVPEEFEGYLGNGSAGSIASGRVAYTFGLEGPAVTVDTACSSSLVALHLAVQSLRQGDSTLALAGGVAIMSTPDVFVEYSRQRGLAADGRCKAFAEAADGTGWAEGVGMLLLERLSDARRNGHPVLAVVRGSAVNQDGASSRLTAPNGPSQQRVIRQALANARLTPADVDVVEAHGTGTKLGDPIEAQALLATYGQDRPAERPLWLGSLKSNIGHTQAAAGVGGVIKMVMAIRHGVAPRTLHVDRPTPEVDWSAGAVELLTEARPWPETDRPRRAGVSAFGVSGTNAHVIIEQPPAIEGTGLGDDAPPTAEHPEERTPADGGPAPQPVAWPLSAKSPEALRDQARQLRHHLTSGATASALSHPLADIGHSLATTRTAFDHRVVVLGTDHDALLRSLAALADGGTDPSVVQGSVRGRGRVAFVFPGQGSQWEGMARELLDTSPVFARQMQACADALSAYVDWSLHDVLRGAPDAPGLDRVDVVQPVLWAIMISLSELWRAHGVQPSAVVGHSQGEIAAAYVAGALSLDDSARVVALRSKALRALSGKGGMLSVPLSEEDLTPQLAAHTGQLSIAAVNGPGSVVVSGDADALEGLFEELTAAGVRARKVAVDYASHSAHVEALREELLTRLGPVAPRPAKVPFYSTVTGERLAGTEALDADYWYRNLRETVRFEQATRALLAQNIGVFVETGPHPVLAVGLQETIDATGGSAVALGSLRRGEGGPDRFLRSLAEAYAHGAPLDWDLLFPGARRVELPTYAFQRDHYWLQIPEGGPADAAGLGLAAVEHPLLAAATSLADGDGLIVTGRLSTRSLPWLADHAVTGTVLLPGTAFVELALRAADLTDCHLLDELTLHTPLVVPDDDPVRVQVRVAAPDPATGRRALTVHARPESPDGDADQEEQGAEWTLHATGYLAVGAHEPAVPDQGQWPPAGATPLDVTDLYPRLADAGYGYGLAFQGLRAAWRLGDDVYAEAELPDEHSDQAGRYGLHPALLDAALHAAGFAGFPDGDGALPGPRLPFSWTGVTLSAVGARALRIRLARTGDDTLTVTLTDPAGEPVATVESLALRPLATNQAPRTPSDLHRVAYTPRDLPADASTAHWAVLDADDLAYALNLPSHPDRDALAALDPAPPVVLTGWPVPDDPAPQAARTVLARALHDIQDWLADDRLADTRLVVVTHNALPADDWQDTDPVAASLTGLLRTAQSENPGRLVLIDTDGHPASWQALPALVATGEPQAALRLGEARVPRLAPAATDAALSVPAAVPAATDASLPVPADTSAWRLAVESPGTLDHLTLIPWAAATAPLEEGQVRIAVRTCGVNFRDVLIALGMYPDPDMLGSEGAGRVVEVGPGVTDLAVGDRVAGILAGGFGPLAVIDAPKVARIPDSWTWEQAASVPLAFATAWYALVDLAALAPGEKVLVHAAAGGVGMAAVQIARHLGAEVYATASPAKWDTLRALGLDDDHIASSRDTAFAEKFPAVDVVLDSLAGEFVDASLRLLPHGGRFVEMGKTDRRDPERIAADHPGVHYRAFDLRESGDRRLREMLDEIFALVEDGTLHPLPYRSWDLRRAPEAFRHMQQARHIGKIVLTVPPALDPDGTVLVTGATGTLGALVTRHLVTEHGVRRLLLVSRSGPQAPGADALLADLAAAGAEATLTACDTADRDQLRAVLDAVPADHPLTAVIHTAGALDDGVLSALTPERLDAVLRPKADAAWHLHELTAGHDLAAFVLFSSAAGLFGNAGQGNYAAANAFLDALAQHRRALGLPATSLAWGLWEERGGMTGHLDTADVGRLSRTGVATLDSAHGLALFDAALSTGQTLLVPLPLDRAALHRQARTGSLPALLSGLVRTTPARRTATGTAATGSVGDTLARRLTAAAPADRDRIVNDLVRDHAAAVLGHGSATAVGLGRAFRDLGFDSLTAVELRNRLGAATGLRLPATLVFDHPTPEELAAHLRDTLLGAADSGAAAVVTTSAEADEPLAVVAMSCRFPGGTGSPEELWELLADGGDAIGALPADRGWDLAGLYHPDPDQPGTSYARHGGFLHDAGDFDASLFGISPREALAMDPQQRLLLETSWEAFERAGLDLRTLRGSRTGVYVGALPSSYGGTLHDAPDGLEGHLMTGNSTSIVSGRLAYTFGLQGPAVTVDTACSSSLVALHLAVQALRSGEVTMALVGGATVMSNPGGLIAFSRQRGLAADGRCKAFSAAADGMGMAEGVGMLLVERLSDAERLGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRDALADARLNASEVDVVEAHGTGTKLGDPIEAQALLATYGQDRPEERPVLLGSVKSNIGHTQAAAGVAGVIKMVLAMRHGLLPRTLHVDEPSTQIDWNAGALSLLAEETPWPETGRPRRAAVSSFGISGTNAHVILEQAPASVPAPASASVPGDSGEAPDPVVVPWVVSGRSADALRAQAGQLAAWADSAAGRDTEPVDVGRALATARSFLEHRAVVVGGDRAELVEALRALATDPAAGSTAADPDGPGGRLGLVFSGQGSQRPGMGRELYTAYPVFAAALDEVCGVLDEVMGAQPPSEGWTGSLREVMFEVSSDLLDETGFTQPALFAFEVALYRLLESWGVAGEVVAGHSVGEIAAAHVAGVLSLADACALVAARGRLMQALPSGGAMVAVEASEEEVAAVLAGRGDEGAGIGAVNAPGSVVVSGVEAAVEEVAARFAGLGRRTRRLKVSHAFHSPLMDPMLAEFRRVVEGLSFAPPRMTVVSTLTGAVASDEELCSVDYWVRHARETVRFGDAVRCMAGAEVDRFAEVGPSGVLAGLVRASVTGEGTRAAVALQRGNRTEPGALVSALGELFVSGLPVDWATYFAGRPLRRVELPTYAFQRARYWLEGAAGAGGRQSAADGQDEVDAAFWEAVEHGDLSALGAGLDVDGEARLADVLPALSSWRRRAEQASVVDAWRYRVTWAPLPEPARASATGVWLLLVPAGAEDAADATRTVEGALAEHGGEVVKVDVAHPEADEARTALAQQITEQFIERFGVTEIGRLRGVVSLLALADGDDPRHPSVSRGLALTLGLVQALGDMELTAPLWCLTRGAVAVDASDGVDGAVQAQVWGLGRAVALEHPDRWGGLVDLPEYVDPRTARRLTGVLTGTGAGAGAGGLGREDQIALRATGAFGCRLTRDTVAPAGDPGEWTLSGTVLVTGGTGAVGGHVARWLAARGAERLVLVSRRGPRAPGADALRDELTAAGAQVEMLACDLSDGSAVTALVAGLAAGGDLTAVVHAAGVLDDGVLASLSVERCAEVLAAKARAAHHLDLATRDVNLDAFVLFSSVSGVLGAAGQANYAAANAHLDAVALHRHALGLPAVSVAWGPWAEGGMAGEDAAAGRLSRDGWTAMAPEPAATAMARAVAAGHPAVMIADVDWQRFAPAYAAVRPGNSLLTGVPEARQAQPQPWSADGERSAWASRLAGLPEEEQRTALLDLVRGQVASVLGHASMQTIDPARAFKEIGFDSLTAVELRNRLNAATGLALPATLVFDYPTPVALAEYVGSQVLGTSSPAVTGPLVVAAVDEPVAIIGMSCRFPGGVQSPEELWDLVVGGRDAISSFPTDRGWDVDALFDPDPEKPGKTYTRHGAFLHDAAEFDPRFFGISPREASAMDPQQRLLLETAWEAFERAGIDPAALRGSATGVFTGTNGQDYATRLRETPQGVEGYLMTGNAGSVISGRLAYTFGLEGPAMTVDTACSASLVALHLAAQALRQGECSLALAGGATVMSTPGAFVEFSRQGGLAADGRCKAFSASADGTGWGEGVGLLLLERLSDAERNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLSASEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPEDRPLWLGSVKSNLGHTQAAAGVAGIIKSVMAMRHGVLPATLHVDEPTSEVDWSAGAVELLTEARPWPEVGRPRRAAVSGFGVSGTNAHVILEQAAETGSTSEEGPAALVPTVVWPISGRDEQALRGQARRLRERLVVEPGLSAADVGLSLATTRSCFEQRAVVVGETRDELLAGLEALAEGREASGLVRGSARGSVNVGFLFSGQGSQRVGMGRELAERFPVFAGVFGEVCGLLDPLLPRPLGEVIAAGPGVLGRTVFTQPALFAVEVAAARLLLSWGVRPQVVAGHSVGEIAAAHVAGVLSLEDACALVAARGRLMEALPAGGVMVALEATEGEVAELLEAHAGAPVGVAAVNGPRAVVVSGDASPVGEIADVVRSWGRRTKRLEVSHAFHSPLMEPMLAEFTEVVSGLEFAAPQIGFVSAVTGGLVGADVVSRPEYWVEHVAQPVRFADAVRAAVDEAGVSLFVEVGPGGALSAMGPDCLDETVGDKQPVVFVPSLRADRPEPLAVTTALATAHVNGVQPDWQAVFAGTGAARVELPTYAFQRGRYWLDASVGGTGDASAVGLATLEHPLLAGVVDLAEEDRTVFTGRLSLTTHPWLADHAVFGSVLLPGTGFVELALAAGQYTGFGHLDELTVHAPLVLPARGAVHVQLVLDGVDDSGRRALTVHSRPEGVAGEQTWTRHATGALTVAEAVDPPAVSAVWPPAGAIEVELDDPYERFAAEGYAYGPAFQGLRRVWRGDGELFAEVELGAQELEAAGRFGVHPALLDAALHPLLLADGSTGQDGDTPTAGRLPFSWTGVSLRATGATTARVTLAFTDGDAVRITVADGDGGLVASVDALVTRPIAAGQLAAGRSGLFEVEWAPVSSSPAGSASWAVVGGGEAGVSAGGPGLGSYEDLAALRRAMDSGAPVPEVVFAHCGGGAEAADVVGGTHTATHAALVSLREWLADERFAGARLAIVTGGAVAVRPGDEVSDLAGAAVWGLVRSAQSEHPGQFVLVDTDGAAEPSSAAAALATGEPQVAVRGGEVFVPRLARADRTPAADSGVRWDPDKSLLVTGASGVLAGLVVRHAVAEWAVRHVVLVSRSGADGLAQELAEAGVSVQQARCDVADREAVAAVLAGIPAEHRLGGVIHTAGVLDDGVIESLTPERLAPVLRPKVDGAWWLHELTADVDLSVFAVFSSAAGVFGAAGQGNYAAANAFLDALALYRHREGLPATSLSWGLWAERSGMAGQLADAQLERLERTGVHPLSSSEGLALLDAALATGRPWLVPVGLDLGVMRAQADLGVTPLFRGLVRAPLRRAQVDKAASNAPDELRRELAVASAADRERMVLDLVRDRTAVVLGFGSRDEVGVDSGFTSMGVDSLAGVDLRNRLSSATGLRLPTTLIFDYPTPAALARYLHTHLVDDAVDQVDIRSVLAELDRLEATLAQVQAGDVGHMKIASRLQDLVGQWHGSGGATPGEDTVTDLEEATADEIFSFIDDNFGSTEVH",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf, ACP-like_sf, Thiolase-like, Thiolase-like, Thiolase-like, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, Thiolase-like, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, ACP-like_sf, NAD(P)-bd_dom_sf, ACP-like_sf, Thiolase-like, Thiolase-like, ACP-like_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,oxidoreductase activity,phosphopantetheine binding,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            152,
            4,
            24,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3634,
                "End": 3732
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2053,
                "End": 2152
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5390,
                "End": 5487
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2158,
                "End": 2609
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3741,
                "End": 4192
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 49,
                "End": 492
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1577,
                "End": 1748
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3658,
                "End": 3724
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5416,
                "End": 5481
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2078,
                "End": 2144
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4935,
                "End": 5117
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5410,
                "End": 5485
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2103,
                "End": 2118
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3130,
                "End": 3357
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2164,
                "End": 2540
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3373,
                "End": 3611
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3683,
                "End": 3698
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1268,
                "End": 1442
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2073,
                "End": 2148
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3653,
                "End": 3728
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2074,
                "End": 2182
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1785,
                "End": 1993
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5413,
                "End": 5485
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2076,
                "End": 2148
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3656,
                "End": 3728
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3650,
                "End": 3762
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 55,
                "End": 431
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3745,
                "End": 4121
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5408,
                "End": 5488
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 5440,
                "End": 5455
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5128,
                "End": 5363
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3634,
                "End": 3732
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2053,
                "End": 2152
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5390,
                "End": 5487
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 976,
                "End": 1077
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 4649,
                "End": 4749
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1335,
                "End": 2144
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2158,
                "End": 2609
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3741,
                "End": 4192
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 49,
                "End": 492
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1577,
                "End": 1748
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3658,
                "End": 3724
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5416,
                "End": 5481
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2078,
                "End": 2144
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4935,
                "End": 5117
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 735,
                "End": 800
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3746,
                "End": 4172
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5410,
                "End": 5485
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4278,
                "End": 4584
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2708,
                "End": 3019
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 610,
                "End": 913
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2103,
                "End": 2118
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3130,
                "End": 3357
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 60,
                "End": 486
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2170,
                "End": 2596
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3749,
                "End": 4175
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1281,
                "End": 1437
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 5007,
                "End": 5113
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 976,
                "End": 1264
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1489,
                "End": 1610
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 965,
                "End": 1265
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4638,
                "End": 4933
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2164,
                "End": 2540
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 608,
                "End": 902
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1478,
                "End": 1777
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 58,
                "End": 308
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 3747,
                "End": 3997
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 2168,
                "End": 2418
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3373,
                "End": 3611
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1497,
                "End": 1574
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3683,
                "End": 3698
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4277,
                "End": 4563
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2167,
                "End": 2593
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1268,
                "End": 1442
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2710,
                "End": 3015
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 612,
                "End": 910
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4280,
                "End": 4581
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2707,
                "End": 3005
            },
            {
                "InterPro-ID": "IPR041618",
                "InterPro-Name": "PKS_DE",
                "InterPro-Type": "DOMAIN",
                "Beg": 3084,
                "End": 3125
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1111,
                "End": 1261
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 4780,
                "End": 4930
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 221,
                "End": 237
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 4649,
                "End": 4931
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2073,
                "End": 2148
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3653,
                "End": 3728
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 57,
                "End": 483
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2426,
                "End": 2543
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 4005,
                "End": 4122
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 316,
                "End": 433
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2074,
                "End": 2182
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1785,
                "End": 1993
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5413,
                "End": 5485
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2076,
                "End": 2148
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3656,
                "End": 3728
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4402,
                "End": 4467
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 3373,
                "End": 3551
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 5134,
                "End": 5306
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1787,
                "End": 1966
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3650,
                "End": 3762
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 55,
                "End": 431
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3745,
                "End": 4121
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2842,
                "End": 2907
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 2546,
                "End": 2672
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 436,
                "End": 548
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 4125,
                "End": 4243
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4279,
                "End": 4601
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 611,
                "End": 926
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2710,
                "End": 3016
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5408,
                "End": 5488
            },
            {
                "InterPro-ID": "IPR036299",
                "InterPro-Name": "Polyketide_synth_docking_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 58
            },
            {
                "InterPro-ID": "IPR015083",
                "InterPro-Name": "NorB/c/GfsB-D-like_docking",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 54
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 3910,
                "End": 3926
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 4649,
                "End": 4813
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 976,
                "End": 1148
            },
            {
                "InterPro-ID": "IPR002364",
                "InterPro-Name": "Quin_OxRdtase/zeta-crystal_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1605,
                "End": 1626
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 2331,
                "End": 2347
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 5440,
                "End": 5455
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5128,
                "End": 5363
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MKNENFEKNDDEKNFEKKNFEKNFDDFEKNFENFEKKFDDFEKNFEKNFDEKKNDEKNDENFEKNENFEKNFDKNFDKNFENFEKNDNFEKNDEKNFDKNDDFEKNFDFEKNDENFEKNFDKNDDFEKNDDFEKNFDKNDDFEKNFEKKNFEKNFDDEKNDDFEKNFDFEKNFEKNFEKNSDFEKNFFEKNFNFEKNFDEKNFDEKNENFEKNF",
        "response#2": "LILKSFCKKNFFKTLNFLIFRNFQNNFRNFIRINKNNFKRNFFSKNFKNQKINFCNWNLFNFNRNKFKNKFNQKKKNSNNFNNDINKFSNFNFSFKNFFLKNNLNLILNKNFLNGNFFYFFKKNDISFKKNKKFNLNNFFKTNIYRNLNNQLKKKNFKILKKNYSFFNFNFLNLNKNKNLNEKHFNKSNLKLNFQLNLNQIKFFKFRKKIFSKGNFFRNFSLNSFFNFNFNQKNFRKFFRNRFFQKNQNKKSSQNNKKIFKFFSKTFFSIVQKKPNFSQKPFKNFNLNFLKNRNQNQKRNCQNRFQNRINRNQIFKKRICQKNTQKFNQIQKKFRKKNWTNLKLNKKNKQNALFRNSRNKKNFFKNFSFNFSQNNFQNFFHQKNLIQNFSLIRNKN",
        "response#3": "MQKTFGFFRKFQKFIKKNLKNKNEFKNFKKKKKNDFKNSKNFPNFNQNLSQNFSKNFFSSNFLDKNLNKFNFKNFKNNFSNKNFSQNFEKKKFKNFFKNKNFNFNSKIQENFSKNNFFNLKNLNNLKNFENNNFKNFENKSNFNFPNFSKSNLNNLNNFNNLNNLNHKNLNKKRKNKNLNSFIFRFDLNLKENFVFKNLNNFFNFNLKNLKKNLNSFFFSNFYKNSNFKKIFNKNLRKFSKKQNFKNSQKKNLNNFKIFKNSFYFLFKKKFRNFRHELLRNFKKIRNFKINFDLLENSFKIKNFKINFKKNFDLSHFENKNLNHFFFEISKNFNFRKNSARNLKLKEQKKSENLKNNLRDFKRRGEKDKKRKMKNLKSQNPERFLRRKRRRRRR"
    },
    {
        "reference": "MTDEAKLLSYLKRVTADLDRTTRRLREAEEQRYEAIAIVGMACRYPGGVRSPEELWRLVADEADAVSHFPQNRGWDLDTLFDPERAGGTSLTQEGGFLYDADQFDAGFFGIGPREATAMDPQQRLLLETSWEALERAGIDPATLRGSATGVFAGVMYHDYGARVVEVPEEVEGYLGNGNAGSIASGRVAFTFGFEGPAVTLDTACSSSLVALHLAAQALRQGECSLALAGGVTVMATPGVFTEFTRQGGLAADGRCKSFSTTADGTGWSEGAGMLLLERLSDAERNGHLVLAVVRGSAVNQDGASSGLTAPNGPAQQRVIRQALANARLSASEVDVVEAHGTGTKLGDPIEAQALLATYGQDRAEDRPLWLGSVKSNLGHTQAAAGVAGIIKSVMAMRHGVLPATLHVDEPTSEVDWSAGAVELLTKSRSWPETGRPRRAAVSGFGVSGTNAHVILEQAADLDVPDAAPVPEGVPVPWVVSARSADALRAQARRLRGHMAAEPGAAVVDVGHSLATARSCFEHRAVVIGRTTDDLLAGLEALAEGRGDSRVRVGAGLAGGRTGFVFAGQGSQRLGMGGRLREMFPVFGEAWDEVVAELDGRLGRPLGEVVFAEEGSEQASLVDRTEFTQPALFAFEVALFRLLESWGVVPDVVAGHSIGELAAAYVAGVLSLSDACALVVARGRLMQALPAGGAMVAVQVTEAEARRLVEGEPSGAVDIAAVNGPESVVIAGDEDVVLRVQEIVRGRGRKTKRLTVSHAFHSPRMEPMLDEFRRVAETVTYHEPRIAVVSAVSGEVAGAELRSAEYWTRHVREAVRFYDAVRCLRSEGVSTFVEVGPDGALSALGQDCLVGEEARGTEFVSTVRAGRDEAESVVAAVGAAHVRGVPVDWAAYYAPYGPRRAGLPTYAFEHQRYWLDASVRTVGDLAGLGLGSAEHPLLGAAVALADGDGVLLTGRLSLATHPWLADHRVQGAVLFPGTAFVELALRAGEQVGADCVEELTLEVPLVLPERGGVQVQVVVGAADEQGGRPVTVYSRPDEDVEDEPWARHAIGMLVPFAASAAVPAEDADFAVWPPQDAVAVDTDGMYDRLAEGGLEYGPVFQGLRSVWRRGSEVFAEVALDDTHRDGAEHDVSAVSAPETTAPVWRLEATGGGTLDALALVAYEETDRPLRANEVRVEVHAAGLNFRDVLITLGMLETKDKLGWELSGVVLETGPDVTGLAPGDRVMGVALGSFAQQAVADHRMLAKIPDGWSYAEAASVPLVFLTAYYSLVDLADLRAGQSVLIHAAAGGVGMAAVQLARHLGAEVFGTASTGKWDALRAQGLDETHIASSRDLEFEPRVLEATDGRGVDVVLDALAGEFVDASLRTLTHGGRFIEMGKTDIRDAEEVAARYPGVHYRAFDLIEAGPERVGQMLAEVLRLFDDGALTVLPVTTWDLLSAPDAFRHLSQARHIGKVVLTVPRTIDPYDTELAVVTRSRSRWRTGRSSARLTANPNSAGEFGLHPALLDAALHAIGFGEFVSDGGAGVLPFSWSGVRLLASGADALRVRVSGVGVGANEVALVVADGSGRPVASVDSLALRPVSADGIGAGRSGASRQSLFRVGWRQVAVPDQAGAGEWVALDRGAGWAQGEGCEVLPDLAALGSAVSAGRSVPRLVVAHFAADREVPVTAGVRGVTAEGLELIQSWLADERFADSRLVIMTRQAVAVDAGEGVFDLGAAALWGLVRTAQSEQPGRVVLVDVDDLDAVSRVVGIGDEPQLAVRDGRVFVPRLMRAEAIDGVPVWDPEGTLLITGASGALGGVVARHVVREWGVRHLVLASRRGAEAPGMTELVAELGELGASAAPVACDVADRDALAAVLAGIPAVHRLAGVVHAAGVLDDGVVGSLTPERLETVLAPKADAAWHLHELAAELDLSVFVLFSSAASVFGGAGQGNYAAANAFLDALAARRRADGLVATSLSWGLWDQAGGMTGQLGEADVARMSRSGVLPISVGEALPLLDAGVTGGDAWLAPVRLDLAALRQQAIATGGVPALLRDLVRVPNRRKAETGGSGAGSRSSLTDKLAGLPQEERAQELLDFVCEHTAAVLGHSGAGMVDPGRNFRELGIDSLAAVELRNRIGGVLGIRLSATLVFDYPSPVLLAGHIGEQLALDEPAPRLPVVAELERLEAAVSAARFDEDSRDDVAARLRKLLSHLDALAASPKREADDGELASASVEELFALVDQELEDL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within Thiolase-like, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, ACP-like_sf, ACP-like_sf, NAD(P)-bd_dom_sf, Thiolase-like sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,oxidoreductase activity,phosphopantetheine binding,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            152,
            4,
            24,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2072,
                "End": 2147
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 407
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2075,
                "End": 2147
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1250,
                "End": 1387
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2077,
                "End": 2143
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1595,
                "End": 1773
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2053,
                "End": 2149
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2102,
                "End": 2117
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2067,
                "End": 2151
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1785,
                "End": 1991
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 470
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2072,
                "End": 2147
            },
            {
                "InterPro-ID": "IPR002364",
                "InterPro-Name": "Quin_OxRdtase/zeta-crystal_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1279,
                "End": 1300
            },
            {
                "InterPro-ID": "IPR015083",
                "InterPro-Name": "NorB/c/GfsB-D-like_docking",
                "InterPro-Type": "DOMAIN",
                "Beg": 2,
                "End": 30
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1171,
                "End": 1249
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1160,
                "End": 1284
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1786,
                "End": 1964
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 407
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 918,
                "End": 1134
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2075,
                "End": 2147
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 935,
                "End": 1239
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1250,
                "End": 1387
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1067,
                "End": 1129
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1486,
                "End": 1584
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 196,
                "End": 212
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1602,
                "End": 1770
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 564,
                "End": 885
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1466,
                "End": 1587
            },
            {
                "InterPro-ID": "IPR036299",
                "InterPro-Name": "Polyketide_synth_docking_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 32
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1781,
                "End": 2146
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2077,
                "End": 2143
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 935,
                "End": 1103
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 283
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1595,
                "End": 1773
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 411,
                "End": 528
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 461
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2053,
                "End": 2149
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 563,
                "End": 856
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2102,
                "End": 2117
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 935,
                "End": 1035
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 458
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 692,
                "End": 757
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2067,
                "End": 2151
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1785,
                "End": 1991
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 291,
                "End": 408
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 563,
                "End": 870
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1152,
                "End": 1457
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 565,
                "End": 867
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "GATSSSSSRTAAASPTSSSSSSRRRPTRRLAASCTPTTSATSSPDPSPRPSRPRSSPPLPARARSRRTPPARRRPSSAAPPPRSPPPPAASRRRPARARPRPPRRSAERASGAPTTRGRPSLSPHRSTPRPTTSRSAKPSPSTRSASTSSPRSSAPSRAATYSLSRPSTAPESHNSSHCPPTLLRAASRWTTSRLRPRHRRAAPERRPSRRPTEPSATAQPRLLGLP",
        "response#2": "AAPPAPPRASPPARPRTPASIRPRTTPPTTTTSPPPPPPLSPRPPTPLPLRPAAAPPPPASPGLSPPLPPSSSSSSSLSRRLRPVDRQRPSPTPPPLPAVRSAPASSPRHARIRVASAAITFPPPTLTSISSRCRSAPPPTRSFPPTSPSSTTPPPSSPHRRLPRSSRPIRRRRSWWRRRRSWAPTPTPRASARRRPTLSRRASTSTARRRTSSSELASTSSSELASTSTSRSRPRTPPAPPTRPARPRRRRTAEGRRRARAPRPPHPLPRRRRQRHPALRLALRLRRALSRRGRRTGRSDGGGVVGAVGADRAGARGRRTRADESDKSESRVTSARRRSACGSSSRFTTSSSTSRARAVAVASTFACFAARGTRA",
        "response#3": "LKDDFNDLNDFKNFKDFNDFDFKNFNDSNFFNYSNKFNHFRNFKIKNLNKFKNFDDLNNFKIFKISNFKNNFKFKKNKKNNSNTDFLFFKQNLNIFKNLNFFDFKFKKKNINFFNKFQFKLNFENFYKKNKFDDFKISFKKNLNFCKLIDFNNFKKLKINDKKVLNKFYRKNFFLRSNEFDLNNSDFNKKRFFFFNFNLILNLNLKFFNSNSNFKSNFKINKINFNSKIKKYFKFKFKFNFKINFTKQKKFKINNFFNFLFKISLLYDLKFKKDLNFNLKNKFNLNKNSLISSNFKLIYSKNKNFNLNKIFKKINNSNFFNFNLNSKKNKFIYKSKINNKKKSKINSKKKKNNLNFKRLNKFDCLFDLKSNFKPNNLNLFKKF"
    },
    {
        "reference": "MDNEEKLVEYLKRVTADLRQVRRRLREVEDQQREPIAIIGMSCRFPGGIHTPEDLWDLVAGGQDAITSFPTDRGWDLDALLDPDPDRPGTSHTRHGAFLHDAPEFDAAFFDIGPSEATAMDPQQRLLLETSWEAFERAGIDPAALRGSRTGVFVGTNVHDYLTGVRETPQEVEGYLMTGNTPSVASGRLAYTFGLEGPAVTVDTACSASLVALHLAAHSLRRDECSLALAGGATVMSAPGAFVEFSRQGGLAADGRCKAFSASADGTGWGEGVGLLLLERLSDAERNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLSPADVDLVEAHGTGTQLGDPIEAQALLATYGQDRPEDRPLWLGSVKSNIGHTQAAAGAAGVIKTVMAMRHGVAPQTLHVDEPTPEVDWSAGAVELLTEARPWPAASAAGRPRRAAVSGFGVSGTNAHVILEQGPEQADTDPLPAQRQPLEDTVFPWALSARNTDALLGQARRLRERLVVEPGLSAADVAFSLGTVRSSFEQRAVVVGETRDELLAGLEALAEGREASGLVRGSARGSVNLGFLFSGQGSQRVGMGRELAERFPVFAGVFGEVCGLLDPLLPRPLGEVIAAGPGVLGRTVFTQPALFAVEVAAARLLLSWGVRPQVVAGHSVGEIAAAHVAGVLSLEDACALVAARGRLMEALPAGGVMVALEATEEEVAELLEAHAGAPVGVAAVNGPRAVVVSGDASPVGEIADVVRSWGRRTKRLEVSHAFHSPLMEPMLAEFTDVVTGLSFSAPRIGFVSAVTGGLVGADVVSRPEYWVEHVAQPVRFADAVRAAVDEAGVSLFVEVGPGGALSAMGPDCLDETVGDKQPVVFVPSLRADRPEPLAVTTALATAHVNGVQPDWQAVFAGTGAARVELPTYAFQRRRFWLDGGRYGNGGGVASAGLASAGHPLLGAVVEVAGDDRTLLSGRLSLASHPWLADHAVRGVVLVPGAAFVELALCAGERVGCGAVEELTLQAPLVLPVEGAVQVQFAVEAPDERGHRAFTVYGRSDEAAEPVSWQEYASGVLELEARPEPEGLAQWPPADAEAVPVESLYDLLRGLGYEYGPAFQGLRRVWRRGEELFAEVSLAEELDGQADQFGIHPALLDGALHTSAVALLEHDDADHREVTGVRLPFAWRGVSLFATGASAARVRLSPAGQDAVSVLVADQDGVPVARVEGLVSRPVAEEQLGAGGGVGRDSLFGVEWVPFAGGDSDALAADVLEVHRFDGLVQDPQGVREAIERALGLIQGWLARERPRGSRLVVVTRGAVGGEVSDLAGAAVWGLVRSAQSEHPGQFVLVDTDGDALAGLPADEPHVMVREGQVLVPRLARVVPATEGGAGGVVWDPEKSLLVTGASGVLAGLVVRHAVAEWAVRHVVLVSRSGADGLAQELAEAGVSVQQARCDVADREAVAAVLAGIPAEHRLGGVIHTAGVLDDGVIESLTPERLAPVLRPKVDGAWWLHELTADVDLSVFAVFSSAAGVFGAAGQGNYAAANAFLDALALYRHREGLPATSLSWGLWAERSGMAGQLADAQLERLERTGARPLSSSEGLALLDAALATGRPWLVPARLDLGVLRTSDQPVPPLLRGLVRRITRRAVTAGANGADSFVQRIAGLSPTEAERAVLELVCGETAAVLGHANAGAVPPGQAFQELGFDSLSAVELRNRLNSATGLRLPATLIFDYPTPAVLAAHIHSATAGTTAGPIAPLTVPGTAVDEAIAIVGMACRYPGGVASPEDLWRLVADGTDAISRFPQDRGWDLEGLFDPQRARGTSLTREGGFLYDADQFDAAFFGISPREALAMDPQQRLLLETSWEALERAGIDPATLRGSATGVFAGVMYHDYATRILEAPEEVEGYLANGNAGSIASGRVAYTFGLEGPAVTVDTACSSSLVTLHLAAQALRQGECSLALAGGVTVMATPGTFIEFSRQQGLSSDGRCKSFSATADGTGWSEGVGMLILERLSDAERNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLTPADIDLVEAHGTGTRLGDPIEAQALLATYGQDRTDDQPLWLGSIKSNIGHTQAAAGVAGIIKAVMAMRHGTLPASLHVDEPTPEVDWDAGAVELLTRARPWPTTDRPRRAAVSSFGISGTNAHVILEHATDTVPATDLTGTASPLSPAATVVPWVLSARGQDALRAQAQRLRDSLHDRPDPALADIGLSLATTRGALDDRAVVLGGDRQQMLDGLAALAAGEPSARLVLGQARPRPPRVVFVFPGQGSQWGGMAVELMDTCPVFAESIARCGQALAQVVDWDLEEVLRDGTFERVDVIQPVLWAVMVSLAELWRACGVRPDAVVGHSQGEIAAACVAGSLSVEDAARVVALRSRALLDLAGQGAMASVFASAEQTELLVAEAAGAAGAVGATGATGVTGEADAADREGRLSVAAVNGPESTVVSGETAAVEAFLDLCERRQIRARRIPVDYASHSAQVEAVADQVREALSGVTGRTGDVPLFSTVTGEWVDGEALDADYWLRNLRRPVRFHEAVRHLARQGHDLFIEVSPHPVLTMGLEDSVTAPGQATTPAADPTDTPTTATAPPGVVATLRRDEGDWSRFLASLAEVHAYGQPVNWAAVLGPARIVDLPTYAFQHRGYWLSDIGGRTPDVAAAGLDPARHPLLGAAVETAGGEQVLLTGRLSTGTHPWLADHVIGGTALLPVSAFVEMALRAGRHVGLPRLDELTLHTPLVVSAADVVRLQVQLDPDDGTGRRPVQIFARTADAPWVRHASGTLTGDAPADFGLLVWPPADATPLPVEGHYDHLAALGYAYGPSFQALRAAWRDGDDLYAEVALDTSENTADYGLHPILLDAAAQTLTLDHRADADTGARMPFAWTGVTLHAPGGGTARVKVSPAGDSAVTIRIADAAGQPVASVESLVLRPVSLQQIAAASSVTQNSLFLVDWTDIPAGPATTTGDTDRRPVLRSRDELEALRRAVADGQPAPALAAFICAAPGATEAPGTDALGNDLAQAVRATTADTLDALRAWLDDDRLEESRLAIVTCRAVVTGTDGAGAGGLNLAQTPVWGLVRSAQAENPGRFLLVDVDDLDAVPDVLARLEGPEGPEGLNEPQVAVRGGQFTVPRLVRPATPTPTADTDTAARDLDPDLDRWNPDGTVLLVGASGGLGQVLARHLVVERGVRRLVLTSRRGEAADGMAELRAELTEAGAVVDIAACDATDRDALAAVLDAIPERHPLTAVVHAAAVLDDGVVTALTPERLDRVLRPKVDTALLLDELTRGLDLGAFVLFSSLSSTLGSPGVANYAAANAFLDGLAQRRRDAGLPATSLAWGLWAQSGGMGDRLSDADLSRMSSGGVTALTTQEGLALFDRALTLDLPVVVPAKIDLAELRRLSGDLLPALLRGLVPGTVRTAAQTADVRTAPALAERLAALGEEERARALLDLVRSQAAAVLGHADVTAVQADTPFRDIGADSLAAVQIRNRLAAATGLRLKATLVFDHPTPAAVARLLLDELAPEPTDAQPAVFADLDALEATLAGLTEAGANSGSSDGAGTDDAVRDRVTARLKSLLWKWTDAQGGGEDMSRPEAGGDTAPVSDDEMFDLIDKELGSL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf, NAD(P)-bd_dom_sf, ACP-like_sf, Thiolase-like, ACP-like_sf, Thiolase-like, Thiolase-like, Thiolase-like, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3449,
                "End": 3544
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1639,
                "End": 1737
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1232,
                "End": 1366
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1655,
                "End": 1733
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3463,
                "End": 3552
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1752,
                "End": 2124
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1657,
                "End": 1768
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 483
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1746,
                "End": 2195
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 406
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3181,
                "End": 3447
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2965,
                "End": 3158
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1380,
                "End": 1619
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3472,
                "End": 3538
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1664,
                "End": 1729
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3497,
                "End": 3512
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1688,
                "End": 1703
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1661,
                "End": 1733
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3470,
                "End": 3542
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3467,
                "End": 3542
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3449,
                "End": 3544
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1639,
                "End": 1737
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 695,
                "End": 760
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1385,
                "End": 1557
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 3185,
                "End": 3363
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2289,
                "End": 2425
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2441,
                "End": 2642
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 572,
                "End": 894
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 197,
                "End": 213
            },
            {
                "InterPro-ID": "IPR015083",
                "InterPro-Name": "NorB/c/GfsB-D-like_docking",
                "InterPro-Type": "DOMAIN",
                "Beg": 3,
                "End": 30
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1753,
                "End": 2002
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 284
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2437,
                "End": 2499
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2010,
                "End": 2127
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 292,
                "End": 409
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1232,
                "End": 1366
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 1915,
                "End": 1931
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 462
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1655,
                "End": 1733
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3463,
                "End": 3552
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2291,
                "End": 2625
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 573,
                "End": 874
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1752,
                "End": 2124
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1225
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1106
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 2691,
                "End": 2849
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1377,
                "End": 1731
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1657,
                "End": 1768
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 483
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1746,
                "End": 2195
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 406
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 465
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1755,
                "End": 2180
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 412,
                "End": 535
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 2130,
                "End": 2243
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3181,
                "End": 3447
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2289,
                "End": 2628
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 571,
                "End": 877
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2965,
                "End": 3158
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 570,
                "End": 856
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1380,
                "End": 1619
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2287,
                "End": 2593
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3472,
                "End": 3538
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1664,
                "End": 1729
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3497,
                "End": 3512
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 3039,
                "End": 3154
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1274,
                "End": 1341
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1042
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 2691,
                "End": 2791
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1688,
                "End": 1703
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2680,
                "End": 2960
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 932,
                "End": 1227
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1661,
                "End": 1733
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3470,
                "End": 3542
            },
            {
                "InterPro-ID": "IPR036299",
                "InterPro-Name": "Polyketide_synth_docking_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 34
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1068,
                "End": 1224
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2814,
                "End": 2955
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1752,
                "End": 2177
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3467,
                "End": 3542
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 2691,
                "End": 2960
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "LQNSEKFENSKFENPKNSEKFENSKFENSENFEKNSNFEKIEKNFENSNFENSKFFENFKIENFFENSKFENDENSNFENFEKFDFKFENSNFKFENFNFEKNFENSFEKFEKFNFEKSNLNENFEKSNLNENFEKSNLNENFFEKFEKSFENFEKSFEKFEKSNFFNFENFENFENFENSKNSENSEISNFENSKFENFENSKFENFKIENSKFKNSKFEIEKSEISNSN",
        "response#2": "FSEKKKNFFDNENFEKNEEKNENEKNFNFEKNEKFEKNFENIEKNEKNKNFEENLEKENEIEKNFFEKKNDIEKKIFEENFENFENNKNQNLLENLKNENENNFFNEKKFEKNFDFEKNEENFFKKKNENFNYDFEKNEKNLQKNEKIEKNFKNENFDEKNFDFFDKKNFFFKNEKNVNFENEKNENEKNLKNFENFKKNFEFEKNSDFSEKNSKEENFEKKKNNENFEKKEKNFNFEKNENFDFEKKNENKNLFENLKNENLKNENFENNLEKNEKNEKNFENLKNENFENNEKNEKNINEKKIDFEKNFGEKNLEKKFEKNENKNFENENFFFKNEKKFFFFKNFENFKNFKNLEKFEKNFFKNEENSE",
        "response#3": "MTWLRARSRTPRGRVRRAARSRRPAITRRPTASRASCRASTATRRRPRRSAERRSLRSSPTRRTRRSSPAAASSSACEGTRSGAAEEEAAEPAERRLPSRFQEGEGRLRPVSTVGSSSHSPTTTAGRSITETSSGTSLRSARNPVPRRSRPYPPSPPLSTTPDSHATPPSLLTSSPTPLPSPSQSSHDQPSPSPSPAPLSSLSSQSPSLPTPTTPPKSTPPPLPPPRSSLSRPPSTSAPSFLLSSLSATTTSALSSPPSSGSLRPALLHLPPPLPMPASMPAFHLSMSKTTPPPPSDSTPSQVTVQTCH"
    },
    {
        "reference": "MTNEDKLRDYLNRVMGELRQSRARLSESEARDHEPIAIIGMSCRFPDGVRSPEDLWRVLVDERHCLTDFPADRGWDLDALYHPDPGHSGTSYTRKGGFLHEAAGFDPEFFGISPREALAMDPQQRLLLETSWEVWERAGLDPAAMRGSRTGVFIGSNDLDYATRLRSVPDGVEGYLATGNLASVLSGRLSYTFGLEGPAVTVDTACSSSLVAMHLAAKALRSDECSLAMVGGVSVMAAPGTFLEFSRQRGLAQDGLCKAFADAADGTGMAEGVGVLLLERLSDARRNGHEVLAVLRGSAVNQDGASNGLTAPNGPSQEQVIRQALDNARLTPDSVDVVEAHGTGTRLGDPIEAEALLATYGQDRPEERPLWLGSVKSNIGHTQAAAGVAGVIKMVMALRQETLPATLHVDRPSTQVDWSSGAVSLLTEARPWARNGRPRRAGVSSFGVSGTNAHAILEEAPAATGNPTEADTDQEPAASASPDRTTTLPAVPWPLSGHTPEALRAQARRLHDTLTTVADGEPQPSPLDLGWSLATTRSTHRHRAVVVGADLPHLLQGVDALASGTPAPHLVRGVAGDTRTAFVFPGQGSQWAGMARELADSSPVFAERLRACEEALAPHVDWSLREVLDGSDLEKADVVQPVLWAVMVSLAALWESHGVRPDAVVGHSQGEIAAACVADALSLEDGARVVALRSRALGVLAGRGGMASLALSAEETTARLAAYKDRLSIAAVNGPHSTVVSGDVEPLHELVAACEADGVRARIVPVDYASHSAHVEEIHDTLLELLAPVTPRPSRVPFFSTVTGEWIDTTVMDAAYWYRNLRRTVQFDVATRTLIAEGFGLLIEASPHPVLAIGMQESVEAAAANCAVLGTLRRGEGGLDRYLLSLGEAHAHGADVDWPAVFAGTGAERVELPTYAFQRRRFWLDGGRDGAGGVASAGLASAGHPLFGAVVEVAGGDRTLLSGRLSVLSHPWLADHSVRGVVLVPGAAFVELALCAGERVGCGAVEELTLQAPLVLPVEGAVQVQFAVEAPDERGHRAFTVYGRSDEAAEPDAWQEYASGVLELEARPEPEGLAQWPPADAEVVPVEGLYDLLGGLGYEYGPAFQGLRRVWRRGEELFAEVSLAEELDGQADQFGIHPALLDGALQTSAVALLQHGGEAAEVRLPFAWRGVSLFATGASAARVRLSPAGQDAVSVLVADQDGVPVARVEGLVSRPVAEEQLGAGGGVGRDSLFGVEWVPFAGGDSDALAADVLEVHRFDGLVQDPQGVREAIERALGLIQGWLARERPRGSRLVVVTRGAVGGEVSDLAGAAVWGLVRSAQSEHPGQFVLVDTDGDALAGLPADEPHVMVREGQVLVPRLARVVPATEGGAGGVVWDPEKSLLVTGASGVLAGLVVRHAVAEWAVRHVVLVSRSGADGLAQELAEAGVSVQQARCDVADREAVAAVLAGIPAEHRLGGVIHTAGVLDDGVIESLTPERLEPVLRPKVDGAWWLHELTADVDLSVFAVFSSAAGVFGAAGQGNYAAANAFLDALALYRHREGLPATSLSWGLWAERSGLTGRLAESDLGRLSRQGVLPLSSEQGVALLDAVLATGRPWLVPARLDLGILRTSDQPVPPLLRGLVRRITRRAVTAGANGADSFVQRIAGLSPAEAERAVLELVCGEAAAVLGYASAGAVAPGQAFRELGFDSLTAVELRNRLNGATGLRLPATLIFDYPTPTALATHIRSSAAGTTTGPTAPVAIAGTAVDEAIAIVGMACRYPGGVASPEDLWRLVADEADAVSRFPQDRGWDLDALFDPERPGGTSLTREGGFLYDADQFDAAFFGISPREALAMDPQQRLLLETSWEALERAGIDPATLRGSATGVFAGVMYHDYGTRVLHVPEEVEGYLGNGNAGSIASGRVAYTFGLEGPAVTVDTACSSSLVTLHLASQALRQGECSLALAGGVTVLATPGVFTEFTRQRGLAEDGRCKAFAAAADGTGWGEGVGMLLLERLSDAERNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLTPADIDLVEAHGTGTRLGDPIEAQALLATYGQDRPEGEPAWLGSVKSNIGHTQAAAGVAGVIKSVMAIRNGVLPASLHVDEPTPEVDWDAGAVELLTEARPWPTTDRPRRAAVSSFGASGTNAHVILEQAADTGPVHAHEGDTTPPSVIAWPISGRDEQALREQAARLGAFVGADASLSAADVGNSLARTRASFEHRAVVVGRDRDELLAGVQALAAGEAAANVVTGRAPAEGAGRVAFVFPGQGSQWIGMGLELAEQSPVFAAALEECGQALAEHVDWDGRSLHEVLRQAEGAPSLERVDVVQPALWAVMVALAAAWRSYGIEPDAVVGHSQGEIAAACVAGVLSVEDGARVVAVRSRAITALAGRGQMVSVPLPEADTVELIRPWADDGQIAVAAVNGPASTVISGDSQAVDALLEKLDAQEIRARRIPVDYASHSPQVALIHDELLRVLDGLTPRAGTVPLFSTVTGQWLGATPMDADYWYRNLRETVRFEAGTRALAAEGWGVFVEASPHPVLTLGIQETLEALDHRGVVTGSLRRQEGGQDRLFVSLAKVHTHGGGPLDRPAFHTGTGAPRVDLPTYAFQRRRYWLEAPAGVPGDLSAAGLQTLEHPLLTGVVDLADEQRTVFTGRLSPATHPWLADHAVFGSVLLPGTGFVELALAAGEHVGHGHLDELTLHAPLFLPEEGAVHLQLVLDGPDTSGRRAVTIHSRAEDEAGGQEWTRHAGGTLAVDADHDTPPALTSWPPADADPVDLTEVYDRFAAAGYAYGPAFQGLRRVWRRDGELFAEVELAGPERDAARRFGVHPALLDAALHPLLLGHGAPQTESEGQGRLPFSWTGVSLRATGATTVRVRLTTDDADTVAVTVTDTAGTPVASVDALVTRPVTAAQFAAGRPSGQSGLFEVEWAPVPTPAAGTASWAVLGGGEVGGVGLGSYDDLAALRRAVDSGAPVPEVVLTFCGGRSETAVVPGTHTATREALALLHEWLADERFAGARLAVVTSGAVAAGPDDEVTDLAAAAVWGLVRSAQSEHPGRFVLLDVDGRAVAGAAVPTALATGEPQVAVRGGELLVPRLARAAKAREVGRDAAGVVWDPEKSLLVTGASGVLAGLTVRHAVSVWGVRHVVLLSRGGADALAQELSEVGVSVRQARCDVADREAVAAVLADIPAAHPLGGVIHTAGVLDDGVIESLTPERLEPVLRPKVDGAWWLHELTAGLDLSVFALFASGAGVFGAAGQGNYAAANAFLDALALHRSRKGLPATALSWGLWAERSGLTGQLTDAELNRMTHHGVLPLSSEQGLALLDSALATDRPWFVPVRIDLGAVRRTGFDHPLLRGLVRVPSRRTVAALDNGTPATDPASLWGRLVALSPAEQEAALLDLVGAQAAAVLGHTDPEQVTTDRPFLDLGFDSLTGVELRNRLTAATGLRLPTTLVFKHRTPAALAAQLRTDLVAVHTDGSGTDTAAPVEAARVPTNGGGTAEAFGELFVEAYRQGRSEEFFRLLRLASEFRPTFDAVRARESVPEPVRLAEGPAEGPDGPMLVCFPSVVGPSGPHQYARFAGPLRDRREVWAVAPPGFVQGELLPKDLATYTDATADAVARRVGETPFVLVGYSSGGWLAHAVASRMEEQGAAPAGVVLLDTYLPEGVVGQLGPELVGGLLERREKFRFDFGDDVWLTAMGGYFRLFDHWRPAAIKAPSLLVRSSEPMPGVPSDTDWRSRWDLPHTAVDVPGNHYTLMEDHAAETARAVRDWVGSLS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, Thiolase-like, NAD(P)-bd_dom_sf, ACP-like_sf, Thiolase-like, NAD(P)-bd_dom_sf, ACP-like_sf, ACP-like_sf, Thiolase-like, Thiolase-like, AB_hydrolase_fold, AB_hydrolase_fold, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3137,
                "End": 3366
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1652,
                "End": 1730
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1660,
                "End": 1726
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3429,
                "End": 3489
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 400
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2944,
                "End": 3121
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3449,
                "End": 3464
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1654,
                "End": 1765
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1685,
                "End": 1700
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1749,
                "End": 2122
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1229,
                "End": 1363
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1636,
                "End": 1734
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3400,
                "End": 3497
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1742,
                "End": 2190
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 487
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3524,
                "End": 3798
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3452,
                "End": 3795
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3419,
                "End": 3494
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1377,
                "End": 1617
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3422,
                "End": 3494
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1658,
                "End": 1730
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1750,
                "End": 1999
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 284
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3137,
                "End": 3366
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1652,
                "End": 1730
            },
            {
                "InterPro-ID": "IPR015083",
                "InterPro-Name": "NorB/c/GfsB-D-like_docking",
                "InterPro-Type": "DOMAIN",
                "Beg": 2,
                "End": 30
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1660,
                "End": 1726
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3429,
                "End": 3489
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2284,
                "End": 2604
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 582,
                "End": 895
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 197,
                "End": 213
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 400
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 579,
                "End": 860
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 583,
                "End": 876
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2285,
                "End": 2587
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1069,
                "End": 1221
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2782,
                "End": 2934
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2944,
                "End": 3121
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1749,
                "End": 2174
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 3449,
                "End": 3464
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1374,
                "End": 1728
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1654,
                "End": 1765
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1685,
                "End": 1700
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1749,
                "End": 2122
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1229,
                "End": 1363
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1636,
                "End": 1734
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3400,
                "End": 3497
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1742,
                "End": 2190
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 487
            },
            {
                "InterPro-ID": "IPR036299",
                "InterPro-Name": "Polyketide_synth_docking_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 34
            },
            {
                "InterPro-ID": "IPR001031",
                "InterPro-Name": "Thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 3584,
                "End": 3794
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 944,
                "End": 1222
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 1271,
                "End": 1338
            },
            {
                "InterPro-ID": "IPR055123",
                "InterPro-Name": "SpnB-like_Rossmann",
                "InterPro-Type": "DOMAIN",
                "Beg": 3002,
                "End": 3118
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 933,
                "End": 1224
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2645,
                "End": 2938
            },
            {
                "InterPro-ID": "IPR020802",
                "InterPro-Name": "PKS_thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 3585,
                "End": 3795
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3524,
                "End": 3798
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 412,
                "End": 546
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 2127,
                "End": 2246
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3452,
                "End": 3795
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1752,
                "End": 2177
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 462
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3419,
                "End": 3494
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2281,
                "End": 2577
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1377,
                "End": 1617
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 2656,
                "End": 2936
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 944,
                "End": 1107
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 2656,
                "End": 2820
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 292,
                "End": 409
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2007,
                "End": 2124
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 3142,
                "End": 3314
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1382,
                "End": 1554
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3422,
                "End": 3494
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1658,
                "End": 1730
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2411,
                "End": 2478
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 702,
                "End": 767
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 1912,
                "End": 1928
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 459
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 2656,
                "End": 2756
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 944,
                "End": 1043
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 581,
                "End": 879
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2283,
                "End": 2590
            }
        ],
        "ipr_mapped": [
            35,
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MKNFNFNFLEYEEIEKKKNFNFKNENEKKNFENEKEINEKNFFKNDENENENLFEKNFNEFEFNFNLNFNLNFDLNDEKNKFSKNFFEKKNEKKIKNLENFFEIFEKKKNDFEKDKNENLFENEKKNFNLNFEILNFSFNDFDFNFFDENSNFKDENFEFKSKNEIKNQNLDEFEKFLNFDENFFEKNEKIEKKNKNFKFENENEKKKNFLDKNFFEKNFLEKIENLFENEFNLNFFDNFKEKNLNEKNLNEEKNFFDKNFKNENKNEKKKKEKNDKKNGFIEIFEFENFEKENCD",
        "response#2": "MIIKNFKKNEIKKFLIKNKIKNIFIIKFFKIYKIINLLIYKIFKKIKIFKLKNFFINNFFIKINNSNNNKIYYIKKNFKKIIIFLNNFFIKKKIIFTNFIKNKKNNFTINFIINSNKKNLKFKNIINIIKKNYIFFLNKNNNKNIFKINFFNKFNNFKNKKKNIKIKKNLISFFIFNLFIIFLKNIINFLIINFKKNFINNFKKNNFLFLNNIFNFIINNKNNLINYKLILINKNFFIIIFSLIIKKKINKIFKINFLINFFFNISFNKKILIINKIKNIFKN",
        "response#3": "LGGRVRGGRGGHGGGGGGRILSSSTASSPPPSSLSSSSIHPSSTSSPSSLSHPSSILSPFPPPNPPPSPFSLLPNSTQSSLFITHTSPSSSSTISHTSPLLSLYSPPIPPFSTNTTTNTTNTTVSPSPLLSLSTSPSSPPPPSPCPSSLHLSSSLPRAPTSPRPHPLFHSPSPTSGVGSSGLALREGWGGGGRRKVGGGRGRGGAGGDRGGAEGGGRGG"
    },
    {
        "reference": "MMKTVIVLIVFSLVMIVVKSDNGYLLDKYTGCKIWCVINNDSCNSHCIGSGGYYGYCYFWKLACYCQGAPRSELWHYETNRCRA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more LCN-type_CS_alpha_beta_dom, Scorpion_toxin-like that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL/defensin, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf, Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 83
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 21,
                "End": 83
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 83
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 70
            },
            {
                "InterPro-ID": "IPR002061",
                "InterPro-Name": "Scorpion_toxinL/defensin",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 70
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 61
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 40,
                "End": 47
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 63,
                "End": 76
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 31,
                "End": 38
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 83
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 21,
                "End": 83
            },
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 83
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 70
            },
            {
                "InterPro-ID": "IPR002061",
                "InterPro-Name": "Scorpion_toxinL/defensin",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 70
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 61
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 40,
                "End": 47
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 63,
                "End": 76
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 31,
                "End": 38
            }
        ],
        "ipr_mapped": [
            64,
            65,
            61,
            62,
            63
        ],
        "response#1": "MNSLLMITACLVLIGTVVEAKEGYPVGRDGCKYSCFRLGKNEYCDTECKKYGASYGYCYAFACWCEGLPDSVPTWPLPNKSCSGGRPEKMIFAGGSRRRRTTKNKKVEANEEDIEAKEEDKKGSVSETDGSRKKASSNGLFYRDESKEEAVTEGVSLLILLVLSASMMLGVECNADAYIRGSDGCKVSCLIGNEGCDKECKGLGGSYGYCWTWGLACWCEGLPDDRTWKSETNTCGGKK",
        "response#2": "MNSLLMITACLVLIGTVWSKKEGYLMDSEGCKYSCFLLGKNEGCDKECKAKKASYGYCYAFACWCEGLPDSVEVWDSKTNTCGGGKSIKTTTSVSEKAKHKVAAKKKKKKKGEKGVVDEPGRDGYPMDHEGCKVSFVIDNDYCVKECKAKKGKDGYCYAWLACYCYGMPDWVKTWEREKNTCGSVDKRFRSSFLVTKILVGGAVATSKVNKKKSGKPEKGAERKDLRDGYIRGSDGCKVSCLIGNEGCDKECKAYGASYGYCWTWGLACWCEGLPDDKTWKYETNTCGGKK",
        "response#3": "MKTFVLFLTCFLLIIGVEGKKGENKDGYLVGSDGCKYSCFTRPGSFCDTECKVKKASDGYCYAWLACYCYSLPDWVKTWDRETNKCGGKGKIQVKGGVVVSHPFVPGTDPKDDKRDGYPVERDGCKYSCFTRPGSYCDTECKAKKASKGYCAWPACWCEGLPDWVKTWDRATNTCGKKKKKTDIRVDKKDGYPVGKDNCVYACDDDKKVGVDGYCDTYCSSKSLKTKDGYCYYGLACLCYGMADAKTGKRINLCCTDDDEPTEDDEDDLDFDKKKFRRRRRVSARDDDDDGRDGYIRGRDGCKVSCVINNSYCDTECKRAGGSYGYCWTWGLACWCEGLPDDRTWKSETNTCGGKK"
    },
    {
        "reference": "KEGYIVNYYDGCKYACAKLGDNDYCLRECKARYGKGAGGYCYAFGCWCTHLYEQAVVWPLPKKKCN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Scorpion_toxin-like, LCN-type_CS_alpha_beta_dom that are essential for its biological function; 2. The protein should belong to Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL, Scorpion_toxinL that shares evolutionary origin and functional similarity; 3. The protein should be classified within Scorpion_toxin-like_sf sharing conserved structural features; 4. The protein must be able to perform the sodium channel inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0019871",
                "GO-Name": "sodium channel inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            30,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036574",
                "InterPro-Name": "Scorpion_toxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 66
            },
            {
                "InterPro-ID": "IPR003614",
                "InterPro-Name": "Scorpion_toxin-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 51
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 45
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 18
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 58
            },
            {
                "InterPro-ID": "IPR018218",
                "InterPro-Name": "Scorpion_toxinL",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 29
            },
            {
                "InterPro-ID": "IPR044062",
                "InterPro-Name": "LCN-type_CS_alpha_beta_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 66
            }
        ],
        "ipr_mapped": [
            64,
            61,
            62,
            63
        ],
        "response#1": "MNSLLMITACLALIGTVWAKEGYLVNYYTGCKYECVKLLGKNDYCDRECKAQYGQSGGYCYAFGCWCTHLYEQAVVWPLPGKSCNSPQGMKYKHSADSVEDFLRRYNYCGGVTVETRSKTIPSHLDNPIGEKNFRSVFLKNGFSEYADGVLIIGNGSCERDGYIRGGDGCKVSCVWGNEGCDRECKAYGGSYGYCWTWGLACWCEGLPESRTWKYENNTCGGKK",
        "response#2": "MNSLLMITACLALIGTVWAKEGYLVNSYTGCKYECFKLGDNDYCLRECKQYGASYGYCYAFGCWCTHLYEQAVVWPLPKKRSNVLLYRCCAHLQLAMRNSYNKHRVYTTVYDPNPGARWKSYYRINECQRNMNSLLMITACLALIGTVWAKEGYLVNYSTGCKYECYKLGDNDYCLRECKQQYGKGAGGYCYAFGCWCTHLYEQAVVWPLPNKTCNRK",
        "response#3": "MNSLLMITACLALIGTVWAKEGYLVNKYTGCKYTCYKLGDNDYCLRECKQKGASYGYCYAFACWCEHLYEQAVVWDYPTKTCGKKITAALALIGTVWAKEGYLVNKYTGCKYTCYKLGDNDYCLRECKQKGASYGYCYAFACWCEHLYEQAVVWEYPTKTCGKKASAFTSAAQNTKGGAVATSRSLASQGTGKADDGYLYDYPTKTCGKRIRGLRAWFKMNSLLMITACLALIGTVWAKEGYLVNKYTGCKYTCYKLGDNDYCLRECKQKGASYGYCYAFACWCEHLYEQAVVWEYPTKTCGKK"
    },
    {
        "reference": "MEAIAQEIQKLHANTDEAGRGKINHDLSVLLASFDTDWEKILKLAAGPLRLALVKVGVDQGIFHALNERSHTLPELIEKTGVAPYLLERILRGQASFGMIKEEGAKGFAANRFTTLLAGPNTSGAVTYIFDILRPIASAIPGFLSERNNPAITSTHDTVFQRAFNTELGGFEWMTGHPEHYGNLFQFLALRPNCEWVDAFPIEAEIGSFTNDPHVEKVLLVDVGGGTGAQSVAFRKKLPHVKGRVIVQEIAETLIHVGAKAPAGIEFMEYDCFTPQPIRGAKFYYLRYVMHLWQDERCVEALKVIITAMGPESRLIIDEAVIPDRDVPWQAACQSILMTAALAGAERTLTEWHNLLDAAGLKILNIFPYDLNMQSVIIAVPK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 143,
                "End": 382
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 155,
                "End": 378
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 219,
                "End": 361
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 143,
                "End": 382
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 42,
                "End": 381
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 35,
                "End": 117
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 33,
                "End": 114
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 215,
                "End": 382
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 37,
                "End": 120
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 155,
                "End": 378
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MPTEPATTFWDRVAAGYDRFERTAPYAPATRAATVAAIGPVAGRRVLDVGTGTGLLALALQRAGARSVTGLDLSPRMLDMARQKAADADGPVEFVCGDAQALPFADGTFDAVTSSYLTWALPDRAAAYREWRRVLAPGGRLVSVDVIWSRRPLARRAHRWYFERVVIPAARRFAPDLDFDLDEIPALMFAATPEQTVEELREAGFTDVAARSVTDIVPAGDDARRRANAMADLVVITATRP",
        "response#2": "MRDDTWDLASSVGATATMVAAARAVASRSPNALIDDPFAEPLVRAVGVDFFTRLADGELTMEEVGDAPGMQRIADAMGVRTRFFDEFFLDATAAGLRQAVILASGLDSRAYRLPWPAGTTVYEIDQPQVIEFKTATLAELGAEPATADRRTVAIDLRDDWPAALRQAGFDPAQPTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSRFATEAMPGITDDEEMRKRTGFDMSALVYHGERNDAAGWLTSHGWRATATTRRELFARYGRPVPDDDDDAAGSLVSAVLR",
        "response#3": "MPRSAPARRPPTARRPAASYYPAMSAVDPVEIAKFDAIAARWWDEDMGDSAIGRFQRRLHDTVLAELAPVAGRRILDVGCGTGILSERMAAAGARVTGLDMSADMIDVARARAKARGLDIDYRVAAAEDLPRVAAFDAVTCLEVLEHVPDPAATLRAMRAALAPGGRLVLSVPDRGPKFYAIVAGEAALARLGLMPPEHKSFYRPAELEAMIAGAGFAVRRSRRVFPMSTFVVAEA"
    },
    {
        "reference": "MAPQNNGYPEPIAIVGMACRLPGEVTSPSKLWDLLVEERSAQSDVPSNRFNVDSWYHPDKTRPGSISTRGGYFLSEDDSYRQFDPFFFGINPKEAASMDPQQRKLLEVVYESFEAAGARLEDVSGSKTACYVGNFTWDIGQMQARDVNHGAPYHMTGGGLTILSNRVNYVFNLKGPSMTIDTACSSTMYALHLACRSLQAGDCSAAIVAGTNLIFGIEQQIGSVRLGVLSPTSACHTFDESADGYARAEAVGSLYLKTLSQAIADGDPIRAIVRGTSINANGKSPGISHPSAQDQEMVIRKAYASAGLDLDQTGYFECHGTGTPVGDPLEVSAIGNVFGNVRTAENPLLMGSVKTNLGHGEAASAISSLIKTILCLEKGEIPATIGIKRLNPDLNLRDGRLKIVQTRSPWPAAQHYLRASVNSFGYGGANAHAILDAVQSYLGDVYQSIPASLPAPEKSASKKYLLLPFSAHSEPTLERNIETISHSFKSGSFSLPDLAHTLGSRRSNHSVRAFGLVSGDADGPQLVDSLRPSKLTVGTAAGASPKLAFIFTGQGAQWAQMGYELVQEYAVVRQTLQDLGRTISKLPNAPDWDLLEALAQPKTKSRVNEAELSQPLTTAVQIAMVDLLRSWGVHPTAVAGHSSGEIAAAYTAGLISAAEAIIIAYQRGAATVKSTQQGAMLAVGQGPEEVLQVIQDIPGVGIACYNAPDSVTLSGTEKAIDEARGRFARAGVFNRKLITSGNAYHSELMTEAGTYYETFLKTCLLPNDPPSTGHASVTMFSSVTEEELSTIELDYWRKNLESPVRFDQATQKLLKQRPEVNVVVEIGPHSALAAPLKAIRTSVGYSPERLVYLSALKRNADSVESMLKLAGSLFLSGWPLDLSTVNADETVYQDETGAERIQYSHGSFIKDLPTYQWTYDEDFLWNESRLSTDIRFRSYPHHDLLGSRLPGTSNAAPAWRNLLSLDQVPWLRDHKVGEDIVFPAAGYVALAVEAVTQIRGSTVTTVDDAYTLRDVNITSAMVLKEGLSTELMFDLFAVTGQPATYQFSVTTVSQGTWTQHATGSVLIDSKNTNDQLLWPDDRNVGSRGGVNKDSYDRRWYAAMDKVGLIYGPGFKTLADIRASPEHLQATAEVSRTATDGLMGHQSEYMLHPTTIDACLQLSIIAAHHGKPESLNKVYLPVAIRKLTIRPQKDSGGVIPLAACGRGHHRGLRSVQTFIDLSSPSNRSLLQAEISFSSLETASSDTVTSKSPQPYTRLVWKPDFDRMSNAEANALFHGTQEDMSASRHFFSELEKVTRLAIRSSAERLPENLQTDHLPAHMHKFLAWLKTEGQALASSEGHDGLTGKDLMEEINSIARNVAHTVPEAAMVAQLNSRMPEIVSGTVGALDVMVEDDLMSKIYEDGFGQVGAYAKLSSVMELVAHKDPSLRILELGAGTGGATKPMLQALQGDTPLPKYAKYDFTDVSKAFLGVAQDKFEGYRNLDFGILDIEQDPAAQGFEEGSYDIVFASNVIHATRNVASSLSHCRRLLKPNGKLMIIETTKQRQVTGFMLGTLPGYWLGADDGRPSSPFLSKALWHQRLLDAGLSGADVVLDDYPEPADCTTLMVSRNVGDAVEHTSMNGTHGVNGVNGFHETNGQNGLNGANGVKSPLVTLIYRNTPQPFQQALEQKYAQLGISTRSMALLDVPTSLERDSRTVMLGELESPLMARMTPDEMHAIQRYTQLAATAIWVTNIDVLQGRDAEKSLVFGLAKSIMTEQPSFHLCSVDVDIYDGKTDYEHSSKLIVETEMAFHDDPNGDLDTELVEKDGLVYISRYVTDDAENANFERHLAIKPTMSSFSESDSSNYSLEFEKVGRLDSFYFKEHSLKALGEHEVLLDIEAAPLDELSIPTLKGQASSSCFGLVMAGTVRAVGPKASKLKKGDRVCCLHPHHFDTAVIVDERVCELLSAHERSEDLISQIHPVVVSLHIVETLLRLRTGDRVLIDCRQAYLAYAIAQVALLAGSTVQVTFNSEPGRGFLQNLGDNAHLVDRRAGFNDSLVGSSFDAIITDAKEGYQLFCESLTYGGRITVLANGAPGDMASAAVSFLNKGTTVGMFDPIDGFANVPLQHSSLVTKALDLLRHNTIRPLPSTQYDLSSFTDAVGHISQEDSVGLAVLTRTSNTAVPIHTVTQPLEFNSQASYLLIGCLGGLGRSLTTWMVSRGARHFVFLSRSGADKPEAAALVQELGELTRTRYYDLTVQVVRGDVSSKEDVSRAIACAKQPIKGVVQAAMVLKDTLFTEMTLGQFNQVLHPKMLGTIHLHELLQDHDLDFFVMTSSVLGAIGAAMQSNYSAANAFLDHMARYRQSQGQQATSIALGMILDVGHVEEHPEVEKALKRNGMYGISVDEYLLMMEFACRRRDLSASARKEGPFKYDPCASAHIVTGMDPTRVSRAGGKSLWLKDNRLRNLVAALGGGSEGEDALNAKQSAGTSTRELLDAARAEGGEAAVKSAILGLILARFSKLVLLPVAKIDPGKSLAHYGMDSMISAELKSWAWREFTVDLPFLGLLDQGLTFDGLADQVVSLAETRSS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within SAM-dependent_MTases_sf, ACP-like_sf, NAD(P)-bd_dom_sf, Thiolase-like, SAM-dependent_MTases_sf, NAD(P)-bd_dom_sf, Thiolase-like sharing conserved structural features; 3. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,methyltransferase activity,oxidoreductase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            20,
            4,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1422,
                "End": 1601
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2491,
                "End": 2546
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2489,
                "End": 2560
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2485,
                "End": 2563
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2175,
                "End": 2395
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 383
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1279,
                "End": 1596
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1960,
                "End": 2128
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 521
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1422,
                "End": 1601
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 271,
                "End": 387
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1853,
                "End": 2154
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2491,
                "End": 2546
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 927,
                "End": 1236
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1096,
                "End": 1191
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1847,
                "End": 1982
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 391,
                "End": 514
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 549,
                "End": 877
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2489,
                "End": 2560
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2485,
                "End": 2563
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 942,
                "End": 1117
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2175,
                "End": 2395
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 437
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 546,
                "End": 847
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 12,
                "End": 440
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 262
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 383
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 550,
                "End": 860
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 546,
                "End": 845
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 175,
                "End": 191
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1279,
                "End": 1596
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 942,
                "End": 1244
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1960,
                "End": 2128
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1430,
                "End": 1535
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 2177,
                "End": 2357
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 2548
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 942,
                "End": 1048
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 677,
                "End": 737
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 521
            }
        ],
        "ipr_mapped": [
            70,
            7,
            233,
            45,
            29,
            30
        ],
        "response#1": "MERRSIDEEGTCTPAETRDSKRSTTKPRRRFSRLTRSTRPMGGWRWFKRPHRRRNLGSETKTMRLRSTSDSRKSSARLRNANRPSKELRQALRKTRKTSTSESQQHGPSALRKVLRKLVRRPRRLSRCRTKSSRSRSSSSQISKPRKPSSKASEPLRKKQPRESREISAGNTRCLLQQRVRAPSLPARRASTRSPPSETGKSRSKSDLKPGLRRNSRPSTESSPRKAPRTASAEMVVLDTSEKSRSLRKRTRLKGSTSSPNRPRRLPPPNELDTRQSRFPPFARRHRRTPPERRLVPQKLEPTNSRSRPPEEHKQRRTQTPLRRFVCRVSK",
        "response#2": "MSTRVSHAVSYTVSYTGASCTSHRSRNSAARSRASSRSRTDRAPASAASRWSASSAPRSAAPRRAQRREPTARSSRHPPGPPVRRARRSTAPARTPLSPAPPPAPPPLPLPLPPSTPVTPPPPAPPASRPGPLSRRPSPRTLRRAPPERRPTPSPRRRRQRRRPPPAPSTTELRTAELRTAEHRTAELRSPAPRRTPDRRRRRAARRPGRTHLTGTAKAKAARSTARRRPAAPASVLPRARPCATHTRTARTSARSIPRASSRASSRSGPSR",
        "response#3": "TTTTTPSPSPPSSSPTSPSPPSATSVTSPPSPTFPTSPPPPAPAPTPAAASTSPPASTPPPTSASAPPSASASAPASASAPAPTSAPPTTSPPTTPSAPPRARTGPALRSPSRAAACTARGHASLHRAGASPPSATSRGPPPASAAALVAAAAAKRARPSPTARPARRRAPPRSASFNPAPARPASPRRPLPRRATERRARTRWRRRAERRRARWARRPSRQRRRRPSRRGPPTRRRRRRRSSTSPSSTSPSSRSSTSGTSPSSSPSRSSRSSSVRTTARATSSPPRRSRSAVTTTTTTSSTRTPCPRARARRRRRSRTQTTAAAPGAADGARRRRARPPRAAARRPRPRGPRRAPLAARAHRRRKRPPSPPPRAVAAR"
    },
    {
        "reference": "MKPYHHPEPIAIVGMACRLPGDIESPSKLWDLLAQERSAQSDVPHNRFNVDSWYHPNKQRPGSIHTRGGYFLSQDDSFRQFDASFFGINPKEAASMDPQQRKLLEVVYESFEAAGARLEDVSGSNTACYVGNFTWDIGQMQARDINHGAPYHMTGGGLTILSNRVNYVFNLKGPSMTIDTACSSTMYALHMACRSLQAGDCSAAVVAGTNLIFGIEQQIASVRLGVLSPTSTCHTFDESADGYARAEAIGALYLKPLSQAMADKDPIRAVIRGTSINANGRSSGISHPSSTDQELVIRQAYASAQLGFEQTGYFECHGTGTPVGDPLEVTAIGNVFGDVRTPESPLLMGSVKTNLGHGEAASAISSLIKTVLCLEKGQIPATLGIKRLNPALDLRDGRLKVVQTLSPWPAAQSYLRASVNSFGYGGANAHAILDAVQSYLGDLYQSIPAPMELKTHSPKQCYLLPFSAHDEQTLNRNIRALSQSLQSGVHLPSLAYTLDSRRSNHSERAFALISTKSDGIQLSEKLSPDSLTFGTAMGSRPELAFVFTGQGAQWAQMGQELVEQYEVVRKTLQNLGATIAGLQNAPDWNLLEALAQPQEKSRINEAELSQPLTTAIQIAMVDLLRSWGVTPVAVVGHSSGEIAAAYCAGHITAKEAIVIAYQRGAATVKSTQRGAMLAVGLGPAEALQVIEDIPNIGIACYNSPDSVTLSGSEKAIEEARKRFLIESIFHRKLKTSGNAYHSNLMEEAGQHYERFLQQSLSRELQSTTESEITMFSSVTETPVETVDLAYWRQNLESAVRFDTATQQLLKSRPEVKIIIEIGPHSALAAPIKAIRTVVGYNSEQLVYLPSLKRNTNSVECLLNLVGSLFLSGFPAPISTVNSASNIGQSPQYFIPDLPIYQWKYGQDIMWAESRMSTDIRFRAYPHHDLLGSRIPGTSNSAPAWRNLISIDSVPWLQDHKVGDSVVFPAAGYVALALEAITQTQGSLTGAYTLRDVNINSAMLLKEGSDTELIFDLHVVVSQQGAYKFVASTVSNGTWTEHATGFVRVGEDYTTNETLRINSTIVGGRGGINKDSYVRRWYSAMNKVGLGYGEAFKTLSNIRANAEYSHATAEVPYNASEGQMAQQSRYAVHPTTLDACLQLSIIAAHNGKPEDLIKAYLPVSISKLTVWPSKIRQDVSLEAFGRGFHRGLRSIQASTGLSTPDGQSLLQAELSFLSLETATKEVDAAKMPQPYTRLIWKPDVDRLTNAQAKALFSQTQADESTAKSYFSSLETLTQLAIRSVVERLPHDLQADSLPGHMQKFFKWLLQENAAISNGALDGLTGEKLIEKIYSIAQSLEQRVPEAAMVAQLNTKMPQIVSGTIGALDVMVENDLLTRIYEDGFGQIGAYARLADFMALMAHKNPRLRILELGAGTGGATRVMLNALEGETSLPKYENYAFTDVSKAFLGVAQETFQAHRHLEFGILDIEHDPASQSFEEHSYDIVFASNVIHATRSVASSLRNCKRLLKPNGKLIIVETTKDWQFTGFMLGALPGYWLGADDGRPYSPFLSKAMWNQVLLDAGFAGADIMLDDYDEPASCTTLIVACNTGEDVRLNENGAKGTNGVNGTNGINSTNSVNVTNDTSGINDTNRMNDNNDMKGMNGGNEGHNTIDTERLNGVKPSTVTLIYRYEPQPIQRAIEREYAQMGITTRSMALEAVTTSLERDARTIMLAELESPLLARMTAAEMTAVQRYTQLATTALWVTNGGVMQGQDPEKSLIFGLAKAIMTEQPSFHLCSLDIDIDNMDLENSNSVSLVMDVERAFHQDPHAEMDTELVEKDGLVYISRYVSDFTENTSFERHLAFKPTMSSVPQGNDALALRFEKVGKANSFYFESQGLRPLTGDEVLIDVDATPLDPLSIDALMGKSSSLSFGMILAGTVRAVGFKTRKLEVGDYVCCLYPHHFDTAVIMHERDCEIIVSEERTGNLLGQIYPSIISLHVASSLRLDRGDHVLIDCQQVHLAYTFAQVALLRAIGVDVTFYSDAGLDKLKHLLGDKAKLISREEALKQASSANFFDAVLTDANDGFQLLVNVARPGGRILALGSSPPTDMIHAAPYFLKKGVTMGMFDPMDGFATNLTQQSKVTSNDGNHDASPELTQSRSLLAEALGLLHHGSIRPLPCERFDLARLPEAISKVAQGDSVGSVVLTRTPDTRVPVHAAEDLLMFNPEASYLLVGCLGGLGRSLTAWMVSRGARHFIFLSRSGADKPEAAALVDELHELARSKYPDLSVQVIRGDVSARDDVKRAISCATKPIKGVVQAAMVLKDKLFSEMSLDDFNKVVHPKMLGSLHLHELLLNHDLDFFVMTSSVLGAIGAAMQSNYSAANAYLDHMARHRRSMGLQAMSMALGMIVDVGHVEEHPEVEKALKRNGLYGISVDEYLINMELACRRQDLSNPIPPQSPYRYDAGAAAHIVTGMDPTRLSRAGGKSLWLKDNRLRNIVVGLGDASGEDERNAENATGVNTAKLLESARAEGGTTAVKSVVLGLVLARFSKLVLLPVEKIDP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, Thiolase-like, SAM-dependent_MTases_sf, Thiolase-like, NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,methyltransferase activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            152,
            20,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1392,
                "End": 1579
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 381
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1257,
                "End": 1574
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 519
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2210,
                "End": 2418
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 173,
                "End": 189
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1866,
                "End": 2186
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 673,
                "End": 735
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1392,
                "End": 1579
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1858,
                "End": 1955
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 911,
                "End": 1220
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 927,
                "End": 1227
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 269,
                "End": 385
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 381
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1257,
                "End": 1574
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 389,
                "End": 512
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 927,
                "End": 1098
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1409,
                "End": 1514
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 546,
                "End": 855
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 7,
                "End": 435
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 2209,
                "End": 2389
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 927,
                "End": 1020
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 543,
                "End": 836
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 438
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 519
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1077,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 260
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 542,
                "End": 843
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 545,
                "End": 872
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2210,
                "End": 2418
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 2525
            }
        ],
        "ipr_mapped": [
            233,
            70,
            7
        ],
        "response#1": "MQQQQQQQQPQQQQQQQQQQQLHQQQPQHPRPRRDPSPSPCRHGPASPRRRAQAAAAQRQSPGAAAAAAQRRGRRRRRPAAAAPAVAAAAARRRARARRRRRRCAPPPAAARRTRRRRRRRNRPRRRRARRRSRRRRRRQRRSRSRPPSSRPRRARPPRPPRRRRPRPRRSPPPPSPPSSPSSSPSPPSSSSSSASTSSSSTPPPPPTPPPCSPTPTHPSPPRAARASPSPSPPPAPPSPAKPPPPTTTSPSSSAFSSSSSATTSSSSSSASSSSSATTTSSSSSASSSSSATPSSSSSSSSSS",
        "response#2": "RPTPARSAPPPRRSSRRRRSSSSSSALRRRRSSRPRRSSSPRRSRPRASPSSSRARRSARSRSAAAPPSASRPRNAATRRRRPRSASSPSTTRRPPTTRRPRPTPARSARPSSRTPATRTATSTTPAPTATAPPTATTTPSRRSATAAPTPVPAPTASPASTATTPPTARPPAPPSTSTGRPSSTTAAPRPPSSSTRRRNSRRPACPRRSSSSPPRTISRHSSSATTTRPAPPSRATSRPSAASSSPRVSSPSAHRRSRRRTRSSPTRT",
        "response#3": "MPSSTISTATTTTTSSTTSASASSTTTSPSTSSASASASASASASAVASSASASASSASATATSAPSTTTTSTRRRRPPPRPPPRRPRPRRHAPRRALRRPRRPRRRRRPRRPRRRPRAPPPRRPPRATTPPAPSTTPPPTRTTNTTRTSTTTTTGTTTRRRRPPPPRRPRRRRRRRRRRRRRRPRPPPPPRPHPRPARAPSPPPPATTTTTTTTTTTT"
    },
    {
        "reference": "MQPHNPYVEPIAIVGMACRLPGDVVSPSKLWDLLVQERSAQSKVPANRFNVDSWYHPDKQRPGSITTRGGYFLSQDDSFRQFDPSFFGINPKEAASMDPQQRKLLEVVYESFEAAGARLEDVSGSKTACYVGNFTWDIGQMQARDINHGAPYHMTGGGLTILSNRINYVFNLKGPSMTIDTACSSTMYALHLACRSLQAGDCSAAVVAGTNLIFGIEQQIGSVRLGVLSPTSVCHTFDESADGYARAEAVGSLYLKTLSQAIADGDPIRAVIRGTAINANGRSPGISHPSAQEQEMVIRQAYARAGLRLDQTGYFECHGTGTPVGDPLEVSAIGNVFGPVRSAESPLLIGSVKTNLGHGEAASAISSLIKTALCLEKGEIPATIGIKRLNPALNLRDGRLKIVQTLSPWPDSQQYRRASVNSFGYGGANAHAILDAVQSYLGEFCQSIPASLTTPGQPSLKRYFLLPFSAHSESTLRQNIKSISHSFKCDVNLPDLAYTLASCRSNHSERAFALVAGDSSCSKLVDSLASDKLTFGTAMGAVPKLAFIFTGQGAQWPQMGHELVQHYAVVRQTLRDLGNVIAKLPNPPEWDLLDALDQPKSKSRVNEAELSQPLTTAIQIAIVNLLRSWGVHPTAVVGHSSGEIAAAYSAGLISAAEAIIIAYQRGAATVKSTQRGAMLAVGIGSDEALQAIHDIPDIGIACYNAPDSVTLSGTEEAVDMARGRFSRAGVFNRKLITSGNAYHSKLMAEAGQFYEASLKQCLLPNDPPSTGNADITMFSSVTEEPVSTLALEYWRQNLESPVHFDQATQKLLKARPEVNLVVEIGPHSALAAPLKAIRAAVGYSPERLVYLSALKRNSDSVECLLKMVGSLFLSGLPFALSTVNADATVHRDDKTGSEMIQYSHGSFIRDLPTYQWVYDEEPLWNESRLSTDIRFRSYPHHDLLGSRLPGTSNIAPAWRNMISLESVPWLRDHRVGDDIVFPAAGYVTLAIEAITQIRRSTISAVTDAYTLPAYEFAVSTFVNGTWTQHATGSVQVDNDSASDQSISSVENMAGSRGGINKDSYDRRWYGAMDKVGLIYGPGFKTLSDIRASPEHHWATAEVSGNATDKLMGRQSQYILHPTTIDACLQLSIIAAHHGKPESLKKVYLPVLIPKLTIWPHHSSQGLPLTACGRGLHRGLRSVQTFTGLSNPNHQTILQAEISFSSLETAVGENGTGKSPQPYTRLVWKPDLDRMTNTQAQILFHGTQDDISTSKHFFSRLEEVTRLAIRSSAERLPENLQADRLPGHMQKFLEWLKMEGLALSTNEAADGLTGESLLDKIDAIARSVEQTVPEAAMVAQLNSRMPEILAGTVGALDVMVEDNLMSRIYEEGFGQTGAYAKLSDVIDLVAHKDPRLRILELGAGTGGATKPMLKALHGDTPLPKYEKYDFTDVSKAFLGVAQDKFQGYRNLDFGILDIEKDPVAQGFPEQSYDIVFASNVIHATRNVASSLRNCKRLLKPDGKLLIIETTKQRQVTGFMLGALPGYWLGADDGRPSSPFLSKTLWHQRLLDAGLSGADIVLDDYPEPADCTTLIMSRNSSEAANHASMNGANHTNGANSINNISEINGVTGVNQLNGAKSLKPSTVTLIYRREPQPLQRALEAKYAQLGISTRSMALEDIPNSLERDSRTIMLAELEDPLMARMTPAEMHAVQRYTQQAATAIWVTNGNVLRGQDPEKSLVFGLAKSIMTEQPSFHLCSVDVDIGDGKADCGNSTTLLVETEMAFHHDPNGELDTELVEKDGLVYISRYVTDDTENANFERYFAIKPTVMALARGESSYYSLQFENVGRVDSFYFKEQSLKPLGENEVLLDVDAAPLDSLSIAALKGQIASPCFGLEIVGTVRAVGSKTSKLKEGNRIHPVVTSLHVVELLLGLHAGDQILVDCRQAHLACIISQVALLEGSRVYVTFDSEAGRDILQQLGNDSHLVDRQANFKQALLGTSFDAIVTDSTDSYQLFDNIINSGGRIVALANTAPVEMVNAAVSFLNKSVTIGMFDPFNGFATAPVQHSSLLAKALKLLRRNVIRPIPSTQYDLSYLPEAVGHISQDDYVGRVVLTRTPNTAVPIHTVAEPLMFNSEASYLLIGCLGGLGRSLTTWMVSRGARHFIFLSRSGADKPEAAALVKELHELTRAQYLDLTVQVVRGDVSIRDDVSRAISCATKPIKGVVQAAMVLKDTLFTEMSLAQFNQVLHPKMLGTIHLHELLQGHDLDFFVMTSSVLGAIGAAMQSNYSAANAYLDHMARHRQSLGLQATSIALGMILNVGHVEEHPEVEKALKRNGMYGISVDEYLLMMEFACRRRDLSSTTNSHDPYKYDPCATAHIVTGMDPTRVSRAGGKSLWLKDNRLRNLVAALGGGNNGDGFNAEQSAGPSTHELLEAARAEGGVAAVKVTTLGLILARFSKLVLLPVHKIDPGKALAHYGMDSMISAELKSWAWKEFTVDLPFLGLLDQSLTFDDLAEKVVALAETKST",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, Thiolase-like, ACP-like_sf, SAM-dependent_MTases_sf, Thiolase-like, ACP-like_sf, SAM-dependent_MTases_sf sharing conserved structural features; 3. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,methyltransferase activity,oxidoreductase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            20,
            4,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1899,
                "End": 2067
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2429,
                "End": 2484
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2117,
                "End": 2336
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2423,
                "End": 2501
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 434
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2431,
                "End": 2497
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1263,
                "End": 1563
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 521
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2432,
                "End": 2505
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1390,
                "End": 1569
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1899,
                "End": 2067
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1066,
                "End": 1163
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 2497
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 926,
                "End": 1187
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2429,
                "End": 2484
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2117,
                "End": 2336
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1820,
                "End": 1902
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 270,
                "End": 386
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 675,
                "End": 735
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2423,
                "End": 2501
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 434
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 941,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1398,
                "End": 1503
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 548,
                "End": 858
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2431,
                "End": 2497
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 11,
                "End": 439
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 436
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 941,
                "End": 1086
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 547,
                "End": 875
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 174,
                "End": 190
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1263,
                "End": 1563
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 521
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 390,
                "End": 513
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 544,
                "End": 844
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 2116,
                "End": 2296
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 261
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2432,
                "End": 2505
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1827,
                "End": 2093
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 544,
                "End": 843
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1390,
                "End": 1569
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 941,
                "End": 1005
            }
        ],
        "ipr_mapped": [
            70,
            7,
            233,
            45,
            29,
            30
        ],
        "response#1": "GAPRPRLRARRARRRPRRGRKRRRRRRSRRRRRAAAAAAAAAAAAAAAATAAAAAAAAAPPRRRRVLGPRRRRPLPRHPRRRRLPLRRPPPRPPPPATPTTATAPRRLPAATAGPTTTPTRRPAAIGSPAPRAPASRSRPRRRPRPPPPPRTSHHPPPPTSTSTSTSTSTSTSTSPSTSRSTAHPPTSSSTFTPTPTSTPSPSPTTTLPPTARTTPRSAETPTPAPSTTPRTPPKTRSTTPSTPTSTSTPRPCSPARPATLRCSLERPSQERGPGRPALFPPRPSVQLLARSPLSLSPSRRPISRLGRLSGRRSSAASSSHSQDSRSRGTVTL",
        "response#2": "MAGSPRSGVFPPRVRARAPRPRPPRAPSRHLSTPHPSDRHPSIRHPSIRHTSIRHPSIRHPSIRHPSTPHASTSRPPQRQPSRARAPGQHPSRQRARPPRPPAASPPPPPAARARPPPPAPRRGPPPPSSLSGRPARSASRGPPAAPPRRGRAAAAAPVVARAARRAAASRPGSSSPGGAAVAPSPASSVSRAQRTPSSPRPPRAPVQAATPAPRAPPARARLSRSGRAARPPGTRPRPRARSRRKGRAPARARVAARRAAAARAAAAVRARAARRARARRGTARARARSRARLRARARLAAAARL",
        "response#3": "MSLIASAAASSLPPGRDHTPRRHDSRSSSPTPSSPSPATAPTPPTPHHPPTPTPRPPPLSRSPPPSTRPRSTPDPSRTRPSPSTPSTPPTPSRRPSSRSSTSSRGTSPPPTRSSAAARPTRARRPSSPMSAAPASSPSSREATTPARPPRSRARHPRAFWVRSRAARPASTLRPSRSRSVTARLRAATSSVRRPSPPTPRRKPCPARSRAARSRRPAAARSRARPSRSRRRPTPSPTRTTPSRARTSSRRERATRRARSPVRRLSCTRARSPAAPRARASAAARRTPPSIRAAARPRPCAER"
    },
    {
        "reference": "MSLQPTATEVGTMYDQYTSLLTDVMAGFIHVGYWDDPEREDTIEVATERLTREIGERLSSVRGQRILDVGCGTGKSAVQIATAHDVHITGITVSNHQIELAQSQYESNTKAGQVNFLFANAMDLPFADASFDGAYAIESLVHMDDRRTALTNIARVLRPGSRLAIADLFLDAGCPNPEVLARFHELFQVPPMPSGDDLKALLHQTGFKVIEFTDIRDTSGLSANF",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 13,
                "End": 222
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 217
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 13,
                "End": 222
            },
            {
                "InterPro-ID": "IPR013216",
                "InterPro-Name": "Methyltransf_11",
                "InterPro-Type": "DOMAIN",
                "Beg": 67,
                "End": 165
            },
            {
                "InterPro-ID": "IPR050447",
                "InterPro-Name": "Erg6_SMT_methyltransf",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 218
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 217
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYELYQPEDGEKLIRELPFSSLIFARQWFVVLGELRENDPPREVTTNEVVEELKFCRKFTVPLRAALRDAGVLKEETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLLDTTGQVTWLREDGFKFRPTSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVPR",
        "response#2": "MNKVVLLCRPGFEKECAAEITDKAGKLEIFGFARVKENAGYVIYECYQPEDGDKLIRELPFSSLIFARQWLEVLAEHKELKEPSNLTVPLRAALRDAKVLTEYPETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGR",
        "response#3": "MTGPTAGPAGPPGPGAGPGPGRGGRPGRRRPAASTGTRSAPRRRGAAAAPRRSAPGRGRAGPAGTGRQPGPAGRRPRARRAGPAAGRAPGAAVRHPRPGSGRRPGAGAGAAGRYPAAPGRHPAAAGHGPAAAPAARRGSGRPGTGPGRGPGPGPGPGTGSGPAGPGRRARRGPGPARGRAAAPAPAAPPAAPAPGPRRAAGRTPAAERRP"
    },
    {
        "reference": "MSHSSHYSPVDSGMVPSSSSTEDHLSPTLSASIVLPAQLNPFAKAYDIPPSSIVQLGWALLLRCHLAIPSPCWSTIDDKTMPRGSDTHALQWESLHLEEGRSISWILQRWEDPSVHWYLSSDQLPGSKSPTLTTMLFLVKEYGLFDPVTPIDPGMGTIIYFYPSDEQPRLHISWNPDVVSSGHAFHLTRSLEHALQTIFLAPSVDIRDVNLFGIWDHQQLLQWNSYCPDPVDRLVQEMFQDVVAATPEASAVAAWDGELNYRELDRLSSRLAGVLQSDFGVVSETIVALCFEKSVWAIVAMLAVVKAGGAFLHIDPQHPPARHQAMIKSTASKLFLCSEQTRDTVVRSVPDCPSLVIHREMFAAQPDHAQQDTVISSGNLGPTNAAYVVCTSGSTGTPKAIVVEHVSLCSSVTAQAKAMDITAGSRVLQYAAYTFDVSIGDIFAALTHGACICIPSNWERAHDLSGAINRLGVNQACLTSTVASLLTPVEVPKLKKLTLGGEPATQQCINMWVDKVALKNIYGPAECTVWCIIQPDVSSGIAVSNIGHAIGARAWIVHPENHDRLMPIGAVGELLIEGPLVARGYLNDPVRTNAVFLAQPPIWLASFGPPPPRSRFYKTGDLARYGPGGALLFEGRKDTQVKLRGQRIELGEVEYRLHQALSDLSPSAAVELVHPKESTAPLLCAFITWDEGIDLDLQPAKPPLSACLTPNARKRFNHTVSLLQTEMERTLPAYMIPGLCIPVHKLPLTTSGKLDRKALRYFCTQHSLAFLSTFENNNVNSPTDGATDSFAAPLETVSPAESTLAQLWAQVLGRKTDSIGRKDNFLSLGGDSLAAMRLVNRAARDAQLTLTVADVFKCPVLADQASLVRPLVQTRNLVPFELMAPGDLQIEDLVAYVAEKCGVLHDQVEDIYPCTPLQDEMMRDSLSGDRTQMGQEVILLAEDLDIPRYLSACARVFQRFPILRTRFVQHSDRLIQVVIRENLGWQRPESLTEYVEADAKEAPALNKPLTRWALTSDSTHCILTMHHSIFDGISLGHILGAIYAVYQSIPLPPDSVSFAAFLAQINEHTSGLSDDSKQFWRSYLRPSPGSGDLPLPIVDSTYRPCANRGTQRLVTFQSGVVPALQQHGLTEATLIRGAWACTLAQLQTSSSTPSDVVFGTILTGRNLHLPGVDALVAPTLTHAPIRIRMSAASNEKPASFLARVQADATAMIPFEHDGMDRIRAIDAQVRAVCDQMQTLLVIQPIPEGLTSASTSPFPGPILSGPRVEAREMRHFHWYGLLVECTLLPTNGFFVRMCYDDKLFSSEDVERLLDDYSQALHELGGGLTEGEEVHLPTERKLDTLTLPGLVAPSGAEDMV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016874",
                "GO-Name": "ligase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 801,
                "End": 872
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 827,
                "End": 842
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 795,
                "End": 868
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 803,
                "End": 867
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 795,
                "End": 872
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 902,
                "End": 1076
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 801,
                "End": 872
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 827,
                "End": 842
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 795,
                "End": 868
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 803,
                "End": 867
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 909,
                "End": 1322
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 638,
                "End": 768
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 261,
                "End": 659
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 388,
                "End": 399
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 233,
                "End": 637
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 795,
                "End": 872
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 239,
                "End": 586
            }
        ],
        "ipr_mapped": [
            29,
            45,
            46,
            30
        ],
        "response#1": "MSDTAERVKKIVIEHLGVDADKVTENASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDAVKFIDNAQKEFLKEAPAKQLDGYIDTVEIGFGFTCKGDDAEGRRVYSSTVSEFMSSPPWSAKTSSYMSKPTRSSSLATVTKRAEIITRTELLSVKLQGSLIPIKQKQFGIKIPDEVAETILTFGDAVKFIDNAQKEFLKEAPAKQLDGYIDVVEIGFGFTCKGDDTELELSIGSVLPNIEELMALSLGYSEASLITYSSPTLLATASELAFSTPFPSISTPFYSKYLNSKNRMSDTAERVKKIVIEHLGVDADKVTENASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDAVKFIDNAQK",
        "response#2": "MSDTAERVKKIVVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFIDKASAARAPPPRCRGGRGRVPPGPGPGGGRRAGAGAGRRPGAGRRCAGPARRRRLHGTPARPGPVPRRPPRPRRLRPPPPPPRPPPPPRPPPPRRPRRRHPGDARRPPAHPPRTMSDTAERVKKIVVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFIDKASA",
        "response#3": "MSDIAERVKKIVVEHLGVEADKVTDSASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLEKAGGSAPKADDKPPKPQLTNYPVNPVTPPLNPAYATPTTPTPTPSSHPPPAPNPTPMSDIAERVKKIVVEHLGVEADKVTDSSFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLEKAGGSAPKADDKPPKPQLTNYPVNPVTPPLNPAYATPTTPTPTPTPTTPTPTPTPTTPTPTPTPTPTPMSDIAERVKKIVVEHLGVEADKVTDSASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLEKAGKS"
    },
    {
        "reference": "MYDVIVVGAGWCGLAAAKTYLQTCPTARLLVVDGDSSIGGTWSKERLYPHLVAEAHYGLFEFSDLPMRREGILPDGRIPSAAVHAYLTEYATKFGLLPRIRLNTWIEDIRQDPTAIGDDKAPYWTLQVAGSSQPLQARKLIIATGLTSEPRMPSFPGREDFEGHVLHSKMMGRADTGKLLNDPSIRHVVVYGGSKSAFDAVYLLLRAGKTVDWVIREGGGGPSIMTPLNILGQPSFRLNNSRVMSLFSPNPFEVAGERSWWQRVMHQRAGTFAQLLVVWFWRVLAYLLQRPWKYDYSVNGKQLKPILGLDSVLWSPATLGVMTHPTLWEDIHSGERVTIRRQNITALGQNKHVVLSNGDRITADMVVCATGWHARHSLFTPDEQLAVGLPSTSSFDPKSQAHWLNLQKAADEEILEEFPLLQNCPIALPPVRCEDDHHLYRFVAPSSGPLAQERLIAYVGFLRTTGAPIVYEAQSLWATAYLTGALHVPALEEREKEVARTNAWIRRRYICGRKVPFALFDFLPYVDMLYRDLGVNSRRKKNAVSE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 2. The protein must be able to perform the monooxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity "
            }
        ],
        "go_f_mapped": [
            14
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 272
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 283
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 344,
                "End": 537
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 272
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 283
            },
            {
                "InterPro-ID": "IPR050346",
                "InterPro-Name": "FMO-like",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 540
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 344,
                "End": 537
            }
        ],
        "ipr_mapped": [
            43
        ],
        "response#1": "MKETENTKKVNENIKNNINNINESKKDIKNNINNINEDKKDINKDINKINEEKEKKIEEYNKKIKEYKKEKEEYINNIKEYKNNKNNEVIEYTKNVKKINENTEKKLKEIYNIDFNKVKIEKVNNIEEINKKLNNKNSLAATYNNKIYINNNIEDENKLIELIAHELTHVKQYEEGIKINYDDKKIKIDYKEYENVKNYNDNKFEKEADKKAKEYINKYNEKIKDKNAY",
        "response#2": "MTTIRNMTAIGTMLVIFAIVSAGADRVDPARRLYASDDDAGMRSRASAAREYAEKMASRVKSMVTDVKKVTREFKAMAMGGAARMRANRGARMAAPAAAEEEDATAEDEDAEDENAEDDAEDDAEDAEEDTAEDDAEEDADENAEDDAEEEDAEDDDAEGAEEDAENDEDDAEDDEDAEEANAEDDAEDDAEDDVEDDAEDNADDNVEDAEEDENVEANA",
        "response#3": "MDADRPDRERAERERAERERAERERAERERAERERAERDRARADTDTDTDTDTDTDADKAERERAERDRERAEAERERAEAERERAEAERERAEAERERAEAERERSRRERERERVRERSERVRERLRERSERERERAEAERERAEAERERADAERERADVERERAERDRARAERERVDRERAERERADRERADADADDADDADADDADDADDADDADDADADADADADADDADADADADADADADADADADADADAERDELAADRDELEADRDELAADRDELAADRERFAADREELEADREELAADRERFAADREELEADREADREELEADRDELASERDRLRSERDRA"
    },
    {
        "reference": "MYDVIVIGAGWCGLVAAKTYLQVCPDARLLLVDGDSSIGGTWSKERLYPHLVAEAHHGLFEFSDLPMRRDTVLPDGRIPSAAVHDYLTEYATKFDLIDRIRLNTWIENVRREPAVIGDNEAPRWMLTVAGSCEQIPTKKIIIATGLTSEPYMPFLPGRQEFEGEVLHSKALGHPQTGDRISDPSVRHAVVYGGSKSAFDAVYLLLRAGKTVDWVIREQGGGPSMMTPLSILGQPSFRLNNSRLLALFSPHPFDTTVKASWWQRVMHRRSGRLAQLAVIGFWRILAYLLQRPWKYNQSANGRRLRPLLALDSLFWSPATLGVMTHPELWDDIHSGERVTIHRQAITALGKDKRVILDNGVELSADLVVCATGWHARHTLFKPEEQLAVGLPSAVSFDPKSQSEWINLQRKADQEIIEEMPILQKSPVPSVPFRCEDDYHLYRFIAPSREPPSHERSIAYVGFLRTAGAPIVYEAQSLWATAYLTGALDVPGPSERISEVARTNAWIRRRYICGRKVPFALFDFLPYVDMLYRDLGVNPHRKANMVAEICGLYQPRDFQGVVSEWLASRGVKDIENV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 2. The protein must be able to perform the monooxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity "
            }
        ],
        "go_f_mapped": [
            14
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 278
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 336,
                "End": 563
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 227
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050346",
                "InterPro-Name": "FMO-like",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 552
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 278
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 336,
                "End": 563
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 227
            }
        ],
        "ipr_mapped": [
            43
        ],
        "response#1": "QLKQKLEEKNKEYEQQLQEKEKQYQEELDSLKKQYEQQIEQLKKEYEEKEKQLKEELKQSSESYQEKLEQLSKKYQEQINQLEQQLKEKEKQLQKNLNKQKEYEQTINQLKEQLQQSKENYQEKLEKLNQELEQKSNQYQQKIKQLEEQLKEKEQQYQKELEEKSNQHLKQINQLEKQLNEYEKKYQQQVEEKLEQKQQELSQEFEQQLQEKEEQYKKELEEKSNEYQQKINKLKQQIKKMKDTL",
        "response#2": "MKFWLATLLLTSTLLLAPSLGKPYSKSPKSKKVNTVRKGNDNEKSEKDDKSEKSEKSEKSEKSDKVEKNETSKESKEKNKDKNDKESKESQEESDKESDEESDEEEESDEDDGSDEEEESDEDESEEDSEDDESEEDDESEDDESDEDDSEEDSDDDESDEDDESDEESDESDEDSDEEDSDEDDDSDEDSDEDESDEDESDEDDSEEDEESDEDSEDDSEESDEDSDEESDEEKKKKKKKRKKKKKKKKRKKKKKKKKRKKKKKKKKKKKKKRKQK",
        "response#3": "ADAEADRRRSEADAEADRRRSEADAEADRRRNEADAEADRRRNEADAEADRRRSEADAEADRKRSEADTEADRKRSEADAEADRLTAEAEARREELDAETTRVGEELDAELAREREELDAELARRREELAAELDAETTRRREELDAELARRREELAAELDAETTRRREELDAELARRREEADAETTRAREELDAELARRREELAAELDAETTRRREELAAELDAETTRRREELATELDAETTRRAEELDAETTRRREE"
    },
    {
        "reference": "MESGTSRTSDTGGTGRAGSTETSGSGDIARTLELLWDTGRRPSRGPKPTLTLDRVVEAAVQIADAEGLEGLSMRRVAAELGTGTMSLYRYVPGKGELLDLMLDRVQRPSENPADLGDGGWRAALEAMARETLALYRRHPWLLQVNQSRPILGPSAMDGMEKVLTLIRPMGLTDPELVSAIIMIDGYVVGAARSQLYQQEAERRTGLTDAEFWRAQVPMLEKVLASGRYPVMASLSEDTFGPDFDHFGFGLQRILDGLEVLVAQRRGESAP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Homeodomain-like_sf sharing conserved structural features; 2. The protein must be able to perform the DNA-binding transcription factor activity,transcription cis-regulatory region binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity "
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": " transcription cis-regulatory region binding "
            }
        ],
        "go_f_mapped": [
            160,
            91
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 107
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR004111",
                "InterPro-Name": "Repressor_TetR_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 112,
                "End": 259
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 49,
                "End": 109
            },
            {
                "InterPro-ID": "IPR050109",
                "InterPro-Name": "HTH-type_TetR-like_transc_reg",
                "InterPro-Type": "FAMILY",
                "Beg": 39,
                "End": 144
            },
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 107
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 56,
                "End": 99
            },
            {
                "InterPro-ID": "IPR036271",
                "InterPro-Name": "Tet_transcr_reg_TetR-rel_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 118,
                "End": 264
            }
        ],
        "ipr_mapped": [
            408
        ],
        "response#1": "MSAPAPPLLGRHRLRLDAKGRLALPAPFRRALPPEAQGRLALTRDPAAPALRLWPPAAWERLHERALRLARRAPGAPAPPPGAAPGAPPAAPPAPPAAEARARALLRALLGETHELPLDAQGRLALPPPLREALGLEEGAELVLTLDPLGPCLRAFPRPAWEALAREAEALDPFSPEARALRTLLLARAWTLTPDAQGRVALPAPLRAHAALGREVVLVGAGATLEVWEPARFEALAREAEAALPALLRRLLPAPAPPAPPAPPAPPPPPPAPAPPAPPPPAPPAPPPPAPPPEGAR",
        "response#2": "MFENFKNFNENFEKNADEKNAFFEKNFENFKNEKNLKNFENKNNENFEKDFFFEKNAFSEKNENAFFENEKNNLNSNLNENKNENEKENKNENFEKNFKNFEKFENEKKNLNFEKFENKNEKNFFENFKNFEKKNFEKFENEKNAFFENSLEKNFEKNFESENFEKDFFHEKNLNSQALNSQTLNSQTLNSQALNSQALNSQNVNSQTQNSQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN",
        "response#3": "MSEKKENFSENEKENFFSEKNFEKKENFSEKEKENFFSEEKNFSSEKEKNFFSENFSEKENFFEKKENFSEKNFFSEKEKENFFSEKNFFSSEKNFFENSEKNFFSEKEKEKNFFSEKENFFSEKENFSEKSEKNFFSENFFEKEKNFFSEKNFEKNFSEKNFFSEKNFFSEKKENFSEKNFFSEKENFFFSEKKSEKNFSEKNFSSEKEKNFFSSEKENFFSEKNFFSSEKNFFSEKEKNFSEKNFSENFSEKEKNFFSEKNFEKKENFFFEKEKNFSEKNFFSSEKNFSEKNFFSSEKNFSENFEKNFEKKENFFSEKEKNFFFSEKEKNFSEKSEKNFFSEKNFSSEKKNFSEKNFFSE"
    },
    {
        "reference": "MGSKETKNTSRRDFLIKGAGAAALGAGAFAISQVPLLEKLASANEDTVKDLLPFPELIESDEIIIRMQNDVRRALKKPLNEIQWIMVIDLKKCVGCSSCTVACVSENVLPPGVVYRPVIEEEIGTFPNVTKKFTPRPCMQCEHPPCTKVCPIGATYKSEDGIVAIDYDKCIGCRYCITACPYGARTFDWGEYHTENTPEIMQYEKEPNYEYGVERVREKKNSPIGNARKCHFCKHRLHKGMLSMCVTTCIGRATYIGDKNDPESLVAELIASPRVMRLKEELGTEPNVYYLT",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd, 4Fe4S_Fe-S-bd that are essential for its biological function; 2. The protein should contain 4Fe4S_Fe_S_CS, TAT_signal that is preserved across related proteins; 3. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            79,
            183,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017900",
                "InterPro-Name": "4Fe4S_Fe_S_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 170,
                "End": 181
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 84,
                "End": 113
            },
            {
                "InterPro-ID": "IPR006311",
                "InterPro-Name": "TAT_signal",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1,
                "End": 43
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 161,
                "End": 190
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 220,
                "End": 258
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 131,
                "End": 192
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050954",
                "InterPro-Name": "ET_IronSulfur_Cluster-Binding",
                "InterPro-Type": "FAMILY",
                "Beg": 79,
                "End": 291
            },
            {
                "InterPro-ID": "IPR017900",
                "InterPro-Name": "4Fe4S_Fe_S_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 170,
                "End": 181
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 84,
                "End": 113
            },
            {
                "InterPro-ID": "IPR006311",
                "InterPro-Name": "TAT_signal",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1,
                "End": 43
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 161,
                "End": 190
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 220,
                "End": 258
            },
            {
                "InterPro-ID": "IPR017896",
                "InterPro-Name": "4Fe4S_Fe-S-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 131,
                "End": 192
            }
        ],
        "ipr_mapped": [
            769,
            746,
            659
        ],
        "response#1": "MFTQITHFFKTFLLTELLKGLSVTGRHMFARKETRLYPEEPVYLPPRYRGRILLTRDPDGEERCVACNLCALSCPVGCISLNKAETEDKRWYPESFRINFSRCIFCGSCEESCPTTAIQLTNDFELGAYKRGDLVFTKDMLLAVGDRIDAPAPAPAPAAPAPAAPAPAAPAPAAPAPAAPAPAAPAPAAPAPAAPAPAAPAPAAPPPAAPPPAPAPPAPAPAPPAPAPPAPPAPAPPAPAPPAPPAPAPAPPPKETP",
        "response#2": "MTTVKEVTHFFKTYLLTDLIRSFAVTGRHMFARKETLQYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVVCPVGCIDLQKAEKEDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFELGEYKRQDLVYEKEDLLISGPGKYPEYNFYRIAGMAIDGKPKPEEKEAKEEEKAPEEKEEKEEKEEKEEKTEEKEEEK",
        "response#3": "ATETTATETTATETTATETATATETEATATETEATATETEATATETEATATEATATETEATATETEATATETEATATETEATATETEATASWRSLLGLEIGSAFFLTMRYFFKPKATINYPFEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIESEPRDDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETRHELYYDKAKLLANGDRWEASLASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASEASNASNASNASNASNASNASNASNASNASNASNA"
    },
    {
        "reference": "MYDVIVIGAGWCGLVAAKTYLQACPDAQVLIVDGDTSIGGTWSKERLYPHLVAEAHYGLFEFSDLPMNGDSVLPDGRIPSTAVHAYLVEYATKFNLIQRIRLNTWIENVRREAGELGMHWTLTAAGSQEQLHAKKVIITTGLTSEAFIPSLPGRDEFEGEVLHSKALGHPQTVERISDPSIRHVVVYGGSKSAFDAVYLLLRAGKTVDWVIREGGGGPSMMTPLSVLGQPSFRLNNSRLLALLSPHPFGTPGEQLSWWQRVVHHRSGQWAQFMILTIWRVMNYLFLRPWGYDSSPNGKRLKPLLGLDSLFWSPATLGVMTHPELWEEIHSGQRVKIHRDAITGLARDKRVMLSSGQELSSADLVVCATGWHARHSFFAPEEQLAVGLPGTASFDPKSQQKWLDLQRTADREITEELPILQKNPIPPPPLRCEDDHHLYRFIAPSRETPSHERSIAFVGFLRTAGAPIVYEAQSLWATAYLTGALEVPEAPQREREIARTNAWIRRRYLCGRKVPFALFDFLPYVDMLYRDLGINPNRKPNQIAELCGLYRPQDFKGVVSEWLANQQAKDVNGN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 2. The protein must be able to perform the monooxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity "
            }
        ],
        "go_f_mapped": [
            14
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 220
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 309,
                "End": 562
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 267
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 220
            },
            {
                "InterPro-ID": "IPR050346",
                "InterPro-Name": "FMO-like",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 547
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 309,
                "End": 562
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 267
            }
        ],
        "ipr_mapped": [
            43
        ],
        "response#1": "MKELEKIIKKLERKIKKVKKKIKKIEEKIEEIESLGKEIKSIIEEIESKIESLERRISSLESRIKSLERRIESKIEKEISSLKSKIKSLEKKIESKIESIKSRIESIKEELKSKLESRISSIKREISSLKSRIKSIKSKIESLERRISSLKSRIKSLERKLKSEIESKIKSLESRIESIESKIKSLERKIESRISSIKSKIESIKEEIESKIESKISSLKSRIKSSERKIESRISSIKREIKSIKKEIEEIKEKIEEIEEKIKELKEEIEKIKK",
        "response#2": "MTADTDDAESDAEADADADADADEADDGTDETAESEAEAADELEAAIEDDLDGLLDREDVADAVEEAVREAVEDVDEATASDVAVESVEVDVDSVAVETVAEDDEGDQEAEADEAEDEADADGEEQADEDADADEADDEADEADEAEAAAEEVDELEAAVESELEGLLEREDVAEAVEEAVRDAVEDVDAETDADVEVESVEVEVESVAVETVDADDE",
        "response#3": "HLKKFNVEFEEKEVKEVKRPFTVKVGEKEYKAKTIIVATGARPRKLGVPGEELTGKGVSYCATCDGPFFRGKVVAVVGGGDSAVEEALYLTRFAKKVYIIHRRDKLRASKILQERLAKEKVEVITPYVVKKVLGKDKVEGVIVAKVDPETKKPIPGTEFKLEVDGLFVEIGLEPNTELLKGKVKLDKRGYIIVNEKQETSVPGIFAAGDVVRGANTVVTAVAEGAIAATSADEYLKKL"
    },
    {
        "reference": "MSQSPTNVPRSYNSVLDLKLASPTNSASGATGGWIVQKFGGTSVGKFPENIVDNIVKVYSQTNRVAVVCSARSSQTKSEGTTSRLLRSADLAENDKDYQPLLNAIEEDHVTNAERIQSEEIKQELIKDTKQEIEHVRELLHACQIIGEISPRSLDSIMAVGEKLSCLFMTALMKDHGLNAVYINLQDVIPLSYDFQKGFDDSFYQFLSQEIGKRVLQCDKEREGEEDVIPVLTGYFGVVPGGLLNGVGRGYTDLCAALAAVALQADELQIWKEVDGIFTADPRKVPNARLLDSVTPEEAAELTYYGSEVIHPFTMEQVIRAKIPIRIKNVENPTGKGTIIYPDNIGRRGEATPPHPPAAFEQLAMSSLLQRKRSATAITAKQDIVVINIHSNKKTLSHGFLAHVFTTLDKYKLVVDLISTSEVHVSMALSIQSDQESQLKHALVDLRKMGTVDVTKKMTIVSLVGKQMVNFIGIAGNMFKVLADEKINIEMISQGANEINISAVINEKDTIRALKSIHAKLLEGGSAIGDSSAVDTRLEALKLS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more ACT_dom that are essential for its biological function; 2. The protein should be classified within ACT-like_dom_sf, ACT-like_dom_sf sharing conserved structural features; 3. The protein must be able to perform the nucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004072",
                "GO-Name": "aspartate kinase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            }
        ],
        "go_f_mapped": [
            61
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002912",
                "InterPro-Name": "ACT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 463,
                "End": 535
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 373,
                "End": 465
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 448,
                "End": 524
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002912",
                "InterPro-Name": "ACT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 463,
                "End": 535
            },
            {
                "InterPro-ID": "IPR036393",
                "InterPro-Name": "AceGlu_kinase-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 343
            },
            {
                "InterPro-ID": "IPR018042",
                "InterPro-Name": "Aspartate_kinase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 36,
                "End": 44
            },
            {
                "InterPro-ID": "IPR001341",
                "InterPro-Name": "Asp_kinase",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 522
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 373,
                "End": 465
            },
            {
                "InterPro-ID": "IPR001048",
                "InterPro-Name": "Asp/Glu/Uridylate_kinase",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 329
            },
            {
                "InterPro-ID": "IPR054352",
                "InterPro-Name": "ACT_Aspartokinase",
                "InterPro-Type": "DOMAIN",
                "Beg": 461,
                "End": 520
            },
            {
                "InterPro-ID": "IPR036393",
                "InterPro-Name": "AceGlu_kinase-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 344
            },
            {
                "InterPro-ID": "IPR045865",
                "InterPro-Name": "ACT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 448,
                "End": 524
            }
        ],
        "ipr_mapped": [
            480,
            481
        ],
        "response#1": "MEENFKIEFEIEKEENINELLEAINLSNKEISKRFDFNKETKFNIEIKEKENKIIIESNDEFKINNFLNILKNNLIKKNINKNIIKEENIENNNKYKLLITFENSINKEISNEIIKELKENLKNKLKNEIKNEKNEIEINSKNFEELENTKNIVEEIIKKNNLKIKIENIENKYIENKNYKIENINENNEIKSNNKNENNDENKKEK",
        "response#2": "MPSFDVVSEANMVEVKNAVEQSNKEISTRFDFKGSDARVELKEREITCYGDSDFKLGQVKDVLRGKMAKRNVDVRFLDYQKAEKKEDEIDSDLIHSGYGEYVAVVVKEDKMEEFVFLGSEDTKLVVHEQQYSRRLACLKPFLKVSLCFPFLFKVEYKAGDYYEVTFEVKKLGEEDVEEEIKKALNKRFKDTEKRSKVDFEVSQQGDELRLTGDDDFKLGQVKDVLIGELAKRNVDVRFLDYGKIEKIGGDKVKQVVTVKKGIDGDLAKKIVRIVKDSKIKVQASIQGDAVRVTGTKRDDLQSTIAMLRKEVTDTPLDFNNFRD",
        "response#3": "MPSFDVVSEANMVEVKNAVEQSNKEISTRFKGSDARVELKERELTLYADDDFKLGQVKDVLIGKMAKRNVDVRFLDYGKVEKAGGDKVKQVITVKKGVSGEVSKQIVRTVKDSKIKVQASIQGDAIRLTGTKRDDLQSVIAILRGELAKRDIDLRSFDYKNAPNYKDGATVTVTTTTTTVTTRTTATTSSTDKDPSFEIVSEVNQIEVNQAVSVIGQRIKKSGIDARVEQRERELTLFGDDDFKLGQVKDVLAGELAKRNVDLRFLDYGKVEKAGDKVKQKVTVKKGISGDFAKKIVRIVKDSKIKVQASIQGDAVRVTGAKRDDLQSTIAMLRKEVTDTPLDFNNFRD"
    },
    {
        "reference": "MSPHISPSKDTPSQRLPIPLSLPTHLGLLAKAYGVPPASILQLAWGLVLRCYFTTSSSRWGTIDMAHEYKEKKNLPIRCEVLELDDTRSIGWILQNWNDPSVHRHLPAEEDTSNVPVSAGSIVILTEDAKDLEVLRDFELTAEWIICFSTSTEKPLLRLSWRPDVIHSELASHLAQLLERALDTTFLSPDIPLSQINLFSILDHQKLLQWNHQYPQSVNRLVHEMFEDMVAARPQATAVAAWDGEVTYQQLDRLSTRLAIKLQTIDLQPESIVALCFEKSVWAIVAMLGVLRAGGAFLHIDPKHPTARQQAMISTTAARIILCSEQTRDTVSRFDSESLSLVVDRKMFAQEPDHKQVALPSPNNLGPRNAAYIVCTSGSTGLPKAIVVEHVSLCTSVTAQAEAMAVGGESRILQYAAYTFDVSVGDVFTALTHGACVCIPSDWERTQDLVGAINRLDVNQACLTSTVASFLTPMNVPKLQKLTLGGEPASKQCIDLWSGKVALKNVYGPAECTVWCVIQKNASSEIPASNIGRGIGARTWIVHPENHNQLMPIGAVGELLIEGPLVARGYLNDAERTTAVFLERAPSWLATFGPLPPQTRFYKTGDLARFEQNGTLFFEGRKDTQVKLRGQRIELGEIEYQIQQACNPVPPLAVELIETKDLQAPLLGAFITWTGGLEISLDQSAVPNGLGPDLDARSHFNELVSRIQANIDRTLPPYMMPGLYIPVQKLPLSTSGKLDRKVLRQYCTQHTRSFLTASEAESSDVIADDATKDDVALHEIVNPGEITLAQLWAHALGRRMESINAKDNFLSLGGDSLAAMRLVNLAARDAQVTLTVANIFESPVLADQARLLRPLSKTKSLAPFELMTRGEASIEDIVGFAAQQCRLLPAQIEDVYPCTPLQEEMMRDSLSNDRTQMGQEVVQISEELDLVRYQVACASVYRRFPILRTRFIEHSGRLVQVVVREDLCWKQPTSLAEYKALDSRERPALGKPLTRWALTSDGTHFILSLHHAMFDGITLGQIQGAIYAVYQCIPLPPPSVSFATFLAHLDDQNAPLSQESQRFWQSYLCPSASLDASITPETQKIDRPRASCGTQRLVQFTSGEVSALQRHGLTEATLVRGAWACTLARHQQKPHASAFSDVIFGTMLTGRNFHLPGVDMLAAPSLTHVPIRIRIDEGDLNGHSARALLARVQADATAMIPYEHDGMNRIRSIEVQTRAVFNRIRTLLVIQPIPEGLTSVSTSPFPGSIVSGPRVEAKEMGHFHWYGLLVECTLLPTKGFFVRVSYDNKMFGTEQVESLLDDYSTTLHTLANGLMDTDIPASLHV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016874",
                "GO-Name": "ligase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 779,
                "End": 856
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 781,
                "End": 852
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 779,
                "End": 852
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 811,
                "End": 826
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 788,
                "End": 852
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 785,
                "End": 856
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 779,
                "End": 856
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 781,
                "End": 852
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 779,
                "End": 852
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 811,
                "End": 826
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 888,
                "End": 1059
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 788,
                "End": 852
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 893,
                "End": 1312
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 785,
                "End": 856
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 623,
                "End": 755
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 226,
                "End": 571
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 373,
                "End": 384
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 247,
                "End": 644
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 220,
                "End": 622
            }
        ],
        "ipr_mapped": [
            46,
            45,
            29,
            30
        ],
        "response#1": "MSDTAERVKKIIVEHLGVDADKVVPSASFIDDLGADSLDTVELVMAFEEEFGIEIPDDAAETILTVGDATKFIDDAVAKQSPPSSAPVLDHSRGGGGSEESALPSLSGCAILHPQRNISANIRGATSPREPRPPGTAGNRRRSSSRRRRYGHRRRRDPSRSRTSIGFSYTSTSKRTMSDTAERVKKIVVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGIEIPDDAAETILTVGDATKFIDDAVAKQS",
        "response#2": "MPEDPRGDPFADPFADLPDRFTDLADRLRELVARLEEARDRPADPPDPDHPVRAALQRRAEELSAVRDRLPEPPADAARTAEERTRELPARVRAAAEQAERAPEHLPETFADADRRLRELLERLRAEAERAERAVAEERRALPDAARQVEERERELRERVAALPAAAERTAAELRAAVERSRRELYERAERALERAREGVAR",
        "response#3": "MSDTAERVKKIIVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFLDEAAKSSSRGPRRRRRLRRRRARPRPRPRRARGRRRPPPRRERAAARRRAHARAAAARRARPREPRPPPRRRPRRTRRRRRRPPRPPRPRPRAPRRRPRPRPRRPRHPPRPARRPRRRPRRPPPGAPRRPRPRPRPRPRPPRPPPPPPPRVPPPPPPPPPPPPPAPPPPPPPRPPQPPRPRKTMSDTAERVKKIIVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFLDEAAKSSS"
    },
    {
        "reference": "MTVHSAESNGSNRIVIIIVGLGIAGLSAAIECHGKGHQVMVFEKYSDLKRTEGDGISIGSNGARVSAKWGDGTFHELIRPLEYQTNKAKVSDYTGYSYGTFELHGYNEGRGYTVNRGQLVYAMHEYARSLGIPIFLNSEVTGYWETEDEAGVVVDGKRISADCVVCAEGIHSSGRLIITGQKMELKETGYAASRGYLDACVTSQDSKLNWILGEEEAEAEDCVYGWLGPGVHFGITTKKRENELFWYCSHKDACTPSKDIDGTINQILHCMEGWAARDQLETVMRKAKKGRFVSETLAIRTPLATWLSPKRRMIVIGDAAHAALPSSGQGGTQAIEDAATLAICLELAGKKDVALALSVTEKLRHQRAQIVQQGGLAVLQFVMNHVDFEALRTDPTMVKPPHPAWILDHDCQEYAYREFVKAAEAIQDGEEYVPHNIPRDGKYSMEYNSQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 2. The protein must be able to perform the FAD binding,monooxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0071949",
                "GO-Name": "FAD binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0071949",
                "GO-Name": "FAD binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            }
        ],
        "go_f_mapped": [
            255,
            14
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 392
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 16,
                "End": 394
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR003953",
                "InterPro-Name": "FAD-dep_OxRdtase_2_FAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 16,
                "End": 45
            },
            {
                "InterPro-ID": "IPR002938",
                "InterPro-Name": "FAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 121,
                "End": 368
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 392
            },
            {
                "InterPro-ID": "IPR050493",
                "InterPro-Name": "FAD-dep_Monooxygenase_BioMet",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 418
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 16,
                "End": 394
            }
        ],
        "ipr_mapped": [
            43
        ],
        "response#1": "MKKIFNFLIFIIIFIISIFFNIKTKINKIEKNYKITKNKNYLELQHIHLYKYKNNLIYYENSKFNIKNKNIDNKNKNKNKKNIKKNNNFNIIYNNYKYINFINYKLDYLKNIFIDIKNFNKKNSIFYIKIDKENLDFIDKIKFIFYNKKYYVNENKFIIFSNKIKDFIIYFTSKNLHILKNNIKILNKNRYYFIYNLNNIKKIKKDIFILNIINNKIKNKINKLKIIFN",
        "response#2": "MSAGRPPAGPAPATETTDVAIIGSGFTGLSTAYHLARRGLRVTVLEAERPGCGASGRNGGQVAPALRTSPAGLAAAVGEERARRMWRLSLAALDDVERIVTEHGIDCDLRTGTVHAARTEREFARLTEAAAVLDRLGVPTRPVDREETARLAGSPVYVGGLHTPRAARVHPLRLTRALAAAAAAAGATVRTDTRVTGLERDAGGRVTAVVTAGGERIRAGAVVLATNAY",
        "response#3": "MAARRAGAAPGPGRAGRGTGAAAAGAAAAAADAATDADLARRVRALGERPVGVTTVAERARLAQELRSLREQRERLRGRLPVVQEQVEAALSAEDDLHRALERAAEAERATRERVRRAQDRLRRTPDPPAPTTPPTAAPTPTARPRPVPTRPVPPTARPRPVPGRPVPPAAPPPPTPPRPPTPPTRPRRPPRPRPRPPPRPRPRPRRP"
    },
    {
        "reference": "MEVSNMTTVTVFILLGLSNNPQVQALLFVLFLVIYLLTLLGNLLMVLVISTDSHLCTPMYFFLRQLSFLDAFYSSIIVPKLLENLLSKGETISFLECFTQISLVIFSGATEACLLSVMAYDRFQAMCHPLLYVVIINRRVCAGLVGASWAIGMGTGLINTLLLAQQHFCGPNVIHSFACELPPVLLLTCSDPCASIVSILTTMSVLGLGTLVLLLGSYSCIIMTALRINSATGRSKIFSTCSSHFLVVTIFYTSGVLRYMIPASGSALEQVLSVQYSVITPLLNPLIYSLKSQEVKVALRRMLARKSRLPL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, Olfact_rcpt, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, Olfact_rcpt that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity,odorant binding,olfactory receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            },
            {
                "GO-ID": "GO:0005549",
                "GO-Name": "odorant binding"
            },
            {
                "GO-ID": "GO:0004984",
                "GO-Name": "olfactory receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            },
            {
                "GO-ID": "GO:0005549",
                "GO-Name": " odorant binding "
            },
            {
                "GO-ID": "GO:0004984",
                "GO-Name": " olfactory receptor activity "
            }
        ],
        "go_f_mapped": [
            0,
            2,
            1
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 236,
                "End": 245
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 281,
                "End": 292
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 176,
                "End": 192
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 129,
                "End": 141
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 110,
                "End": 126
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 288
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 50
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 59,
                "End": 80
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 104,
                "End": 126
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 270,
                "End": 296
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 31,
                "End": 306
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 236,
                "End": 245
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 281,
                "End": 292
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 176,
                "End": 192
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 129,
                "End": 141
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 110,
                "End": 126
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 288
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 50
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 59,
                "End": 80
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 104,
                "End": 126
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 270,
                "End": 296
            },
            {
                "InterPro-ID": "IPR050516",
                "InterPro-Name": "Olfactory_GPCR",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 301
            },
            {
                "InterPro-ID": "IPR000725",
                "InterPro-Name": "Olfact_rcpt",
                "InterPro-Type": "FAMILY",
                "Beg": 31,
                "End": 306
            }
        ],
        "ipr_mapped": [
            0,
            1,
            2
        ],
        "response#1": "MQSSYLFIHPPFIMLSAFSQSLGLRFYKKTRGKMDPGNHTAVTEFILLGLTDDPVLRVILFIIFLCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSVITPNMLVNFLVERSTISYVGCMTQLYFFVAFVTTECFMLAVMAYDRFVAICNPLLYSTKMSTQVCVQLVIGSYVGGFLNASIHTCCTFRLSFCGSNVINHFYCDLSPLLKLSCSSTHVNELVISISAGSITMVTVLVIAISYSYILITILKMRSTEGRHKAFSTCTSHLTAVTLFYGTITFMYVMPKSSYSTDQNKVVSVFYTVVIPMLNPLIYSLRNNDVKGALKKQLGKKTFSS",
        "response#2": "MAEGNHTAVTEFILLGLTDDPVLRVILFSIFLCIYLVTVLGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSVVTPKMLVNFLVERNTISYLGCSTQFFFFLTFMTTECFMLAAMAYDRFVAICNPLLYSTKMSTQVCVQLVVGSYIGGFLNASIHTGCTFRLSYCGSNKINHFFCDVSPLLKLSCSSTHVNELVISTVAGSITMVTVSVIAISYTYILITILKMRSTEGRHKAFSTCTSHLTAVTIFYGTIIFMYVQPKSSYSTDMNT",
        "response#3": "MAYDRFMAICNPLLYSTKMSTQVCIQLVVGSYIGGFCNASIHTACTFSLSFCNSNIINTFFDSVLSYCDSNVINHFYCDISPLLKLSCSDTSVNELLISSVSGSIIMVTVLVIAISYSYILITILKMRSTEGRHKAFSTCTSHLTAVTLFYGTITFMYVMPRSSYSTDQNKVVSVFYTVVIPMLNPLIYSLRNKDVKGALKRQLSKT"
    },
    {
        "reference": "MPISIPKGEKLMDLLSMKGKVTIVTGASGPRGMGIEAARGIAEMGGNVALTYAGRKEGGEKNAAALEKEYGIKAKAYKLDVANYESCCQLVKDVIADFGQIDAFVANAGKTADSGVLDGEISAFEEVIQTDLLGVAYCAKAVGHHFKERQTGSFVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEWRDFARVNSISPGYIDTGLSDFVDKETQKLWHSMIPMGRDGDAKELKAAYVYFCSDASTYTTGSDLVIDGGYCAR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0050664",
                "GO-Name": "oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor "
            },
            {
                "GO-ID": "GO:0016616",
                "GO-Name": " oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor "
            }
        ],
        "go_f_mapped": [
            4,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 263
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 265
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 146,
                "End": 162
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 194,
                "End": 211
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 193
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 99,
                "End": 110
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 38
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 227,
                "End": 247
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 26,
                "End": 263
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 265
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 146,
                "End": 162
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 194,
                "End": 211
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 193
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 99,
                "End": 110
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 38
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 227,
                "End": 247
            }
        ],
        "ipr_mapped": [
            9,
            7
        ],
        "response#1": "MDMLRLDGKVAIITGASSGIGEATAYHLAKHGAKLVLAARRENELQRVASLCQEVNPSISLPPKVVVTDVSKKDECQKLVDTTLSTFGRVDIAVNNAGIMMEVEDEWDRTIDVNLKGTVNVMKAVLPHMLARKSGSIVNVASIAGVVGGVGGSVYTATKHGIVGLTKNVAANYVKDGIRCNAICPYGVETPLLANAPEEFKA",
        "response#2": "MSSKRLEGKVAVITGGASGLGEATARLFHQEGAKVVIADIQEELGNKVAQELGEDKAVFVRTDVSKEDDVKKVVDTAVEKFGKLDVMFNNAGIEISKPVTEMTEEDWDKVMAVNVKGVFLGTKHAAAVMIKQKRGSIINTASVSGTMAAARHGITVNAVAPGVIETPLTEKLAHDKDALKKVWGSSTVLGRVAQPEEIARAALFLASDESSYVNGATLPVDGGGTTGVHV",
        "response#3": "MSLLFFIRSDARPTPWFVVSLPPAAASRPTRAVPAFLQKVEMTMAALKGKVAIITGAASGIGEATARLFAAEGAKVVVADLDEERGNKVAEEIKAKGGEAVFVKTDVTKEAEVEAVVAKAVETFGRLDVAFNNAGIAEEETPVTETSEEKWDRTIAVNLKGVWLGMKHELKQMLKQGHGTIVNAASVAGLVGCVTSSVYVASKHGVVGLTKTAALEY"
    },
    {
        "reference": "MSDMKAIHFGGGNIGRGFVAEFLHKSGYEVVFVDVMDAIINALQQNKSYTVTEVGTSETKSKTIDNYRAINSKTDEDKVVEEIATADIVTCAVGPNILKFIAPVIAKGIENRKKDSPIAVIACENAIGATDTLRKFIEEKLSDSTKSNIQDKARFANSAIDRIVPMQDENAGLNVKIEKFYEWCVESKPFLPSQPPKIEGVHFVEDLTPFIERKLFTVNTGHATAAYYGYNRGKECIHDVLQDKELNEIVRNTLKETAHLIVNKHEISEEDQNQYVEKIIKRISNPVLKDNVERVGRAPLRKLSRNERFIGPAAHLAEMGAKYDALLGGIEMCLRFQNVEGDDESFELAKILKENSSSDATEKITGLERNHTLFPAVEEVVKKVQA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Mannitol_DH_N, Mannitol_DH_C that are essential for its biological function; 2. The protein should belong to Mannitol_1_phos_5_DH, Mannitol_DH, Mannitol_DH, Mannitol_DH, Mannitol_DH that shares evolutionary origin and functional similarity; 3. The protein should be classified within NAD(P)-bd_dom_sf, 6PGD_dom2, 6-PGluconate_DH-like_C_sf sharing conserved structural features; 4. The protein must be able to perform the mannitol-1-phosphate 5-dehydrogenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008926",
                "GO-Name": "mannitol-1-phosphate 5-dehydrogenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008926",
                "GO-Name": "mannitol-1-phosphate 5-dehydrogenase activity "
            }
        ],
        "go_f_mapped": [
            265
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR013131",
                "InterPro-Name": "Mannitol_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 195
            },
            {
                "InterPro-ID": "IPR013118",
                "InterPro-Name": "Mannitol_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 206,
                "End": 348
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 204
            },
            {
                "InterPro-ID": "IPR013328",
                "InterPro-Name": "6PGD_dom2",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 209,
                "End": 386
            },
            {
                "InterPro-ID": "IPR023028",
                "InterPro-Name": "Mannitol_1_phos_5_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 381
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 171,
                "End": 186
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 16
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 153,
                "End": 166
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 117,
                "End": 130
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 206,
                "End": 385
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013131",
                "InterPro-Name": "Mannitol_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 195
            },
            {
                "InterPro-ID": "IPR013118",
                "InterPro-Name": "Mannitol_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 206,
                "End": 348
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 204
            },
            {
                "InterPro-ID": "IPR013328",
                "InterPro-Name": "6PGD_dom2",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 209,
                "End": 386
            },
            {
                "InterPro-ID": "IPR023028",
                "InterPro-Name": "Mannitol_1_phos_5_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 381
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 171,
                "End": 186
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 16
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 153,
                "End": 166
            },
            {
                "InterPro-ID": "IPR000669",
                "InterPro-Name": "Mannitol_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 117,
                "End": 130
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 206,
                "End": 385
            }
        ],
        "ipr_mapped": [
            7,
            714,
            715,
            716,
            718,
            503,
            504
        ],
        "response#1": "MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSSSGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKAQGESPLNIIACENMVRGTTQLKGHVMNALAEDDKAWVEEHVGFVDSAVDRIVPPSASAATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITA",
        "response#2": "MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSSSGDDVVDLIAQVDLITTAVGPVVLERIAPAIAKGLVKRKEQGESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILN",
        "response#3": "MKKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGENEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHVNLVKGIAGAMHFRSEDDPQAQELAALIADKGPKAALAQISGLPADSDVADQAATYISNMKANSEVVAEIVTATKATQ"
    },
    {
        "reference": "MTRTARAKSAPAVGPGRPRDTDLDTAIIHATRQRLAEQGYSQISLSEIAAAAGTTRPSLYRRWPTKLDLVVAALEWGFRAQTDSYPTEAISELEPREAFIEAIRRLDPAYFNADAMLLMGNFMGEARRTPELLDVVRERAVNPRLAQLEAVLLKLREDGRIRADTDVRTVATLCFGAYFATFLREDADHRAIAERVCDTLWPSMVADG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Homeodomain-like_sf sharing conserved structural features; 2. The protein must be able to perform the DNA-binding transcription factor activity,transcription cis-regulatory region binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity "
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": " transcription cis-regulatory region binding "
            }
        ],
        "go_f_mapped": [
            160,
            91
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 83
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 21,
                "End": 81
            },
            {
                "InterPro-ID": "IPR050109",
                "InterPro-Name": "HTH-type_TetR-like_transc_reg",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 206
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 40
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 48,
                "End": 71
            },
            {
                "InterPro-ID": "IPR011075",
                "InterPro-Name": "TetR_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 199
            },
            {
                "InterPro-ID": "IPR001647",
                "InterPro-Name": "HTH_TetR",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 73
            },
            {
                "InterPro-ID": "IPR036271",
                "InterPro-Name": "Tet_transcr_reg_TetR-rel_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 96,
                "End": 202
            },
            {
                "InterPro-ID": "IPR009057",
                "InterPro-Name": "Homeodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 83
            }
        ],
        "ipr_mapped": [
            408
        ],
        "response#1": "MFRGATLVNLDSKGRLTVPTRYREQLIESATGQMVCTIDIHPCLLLYPLPEWEIIEQKLSRLSSFNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKADIEAEQSATQRLSELINGEGGCHASAEGRHAGGAGRAHGAAAAAGGAAVAAGAAAGAAAAAGGAAGGAAAGAEGPGAGAGVAGERGAAPAAAGAITGIAAAGAAVKAEKC",
        "response#2": "MEPDAARRAEEARRRAAAERAAARAFVEAMRAEREREAAERARREAEEREERERARRELERQRRERAAARAPAPPSAPDPGPRAEARRRAERSLRAEAARRAAREEALRAEARERQQRARREREQRRERERAERRARAAARAAADRDEAARRERARLRRFLGAEAPRREPGPPPRPAPAAPPPAAPPTAPPSAAPPLPPPAAPPAPPPAAAPPAAPPPAPAPAPAAFEAYEAARVVRRMFRGATLHNMDSKGRLVVPTRYREQLGAEGQLVCTIGLDRCLLGYPLPEWEIIEQKLSRLSSMNPQARRVQRLLLGHASECQMDGAGRLLLAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVEEDIQAEQDAFSADGSLEDLLQNLSL",
        "response#3": "PPPPPPPPPPPPPPPPPPPPSPRPPPPPPPPPPPPPSPPPPLPPPPPPPPPPPPPPPPPPPPRPPPSPSPRERHAVERARAEALERAAREAETREREAEARAREAEARERAAEAAVREREARAREAEERAEAAAVEREAESRERERARAEREALEREREARERLARAREREAEEAEREREREERARAAAKERRAAEAERAASERERAAAERAAAEERREREERARREGFWRERRAREREAAAAEAELERREAEAAARERRAEEREREAEARMRRQRERARR"
    },
    {
        "reference": "MGIVEEAHNVKILGSGEQTVVLAHGFGTDQSVWKHLVPHLVDDYKVVIFDNMGAGTTNPDYFDFERYSTLEGYAYDVIAILEEFQVGSCIYVGHSVSAMIGVIASIARPDLFTKLVTVSASPRYLNDMDYYGGFEQEDLDQLYEAMRSNYKAWCSGFAPLVIGGDMDSVAIQEFSRTLFNMRPDIALSVLQMIFQSDLRHLLPHVSVPCHIIQSMKDLAVPVVVSEYLHQNLGGGSIVEVMSTEGHLPQLSSPDVVIPVLLRHIHHDIAI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AB_hydrolase_1 that are essential for its biological function; 2. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 270
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 10,
                "End": 264
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 257
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 270
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 10,
                "End": 264
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 257
            }
        ],
        "ipr_mapped": [
            35,
            36
        ],
        "response#1": "MPRPRPRRPRPRRRPRRRPRPRRRPPRRPRPPRRDPRRPRPRRPRRPRRPRRRPPRRRPPPRRRPPPRRRPPRRPRTVTTTTAIATAAAATGAAAAYTALRRRRWRRHGERFVTAADGTELFVRTAGEGPDTALLLHGIGSSSTLWLRNLPALAEHHRVVAVDLLGFGRSPKPDDGRYTVADQARRVAAALAALAVPAERLHVAGNSLGGIVALHLAADHPGLVRTLTLVAPAITTTRPRRRTPARALRAVLAPRLGPPPGVFTLALATRGPLGTRTLLRWCYRDPARVPEDVVDLFAEHTRRRGATRAFHETTRDIITGGTHPDEVARRLAAVTAPVTLLGAEDDQLVPPASLDRAAELLGPERVTRRTLPGVGHALQLEAPAEVNAALLAAWEETA",
        "response#2": "MTTGTTTPAAPAPAAPPPAARRTVTTADGVRLAVRDYAPEGPERGTVILVHGLYLAAPIWELTARHLAAAGHRVVVPDLRGHGESGKPAPETYGIAEQVADLEALRTALGVERCHIAGHSLGGMVALEYAGRHPERVASLTLLAPALTFAGTSAAERTVRTLTARPAAAAAPAAAPGAAPAAPAATPAAPAPAPAPAATAPAPAPAPAPAPAPAPAPAPAPAPGRRRVRPALPPRQLLRALPALLRNTELTTRLLTRLAYRSTDPRVVEFCTRQIRRAGPVTTYRCFLASLTHDVSAVAPRLTTPTLVLHGTDDPLVPVAGSRRLVDLLRAGGADVTYREIPGAGHDLPLTHAAEVAAAILERTGH",
        "response#3": "MTLTPTTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPKRRRTAAAAAGTAAAGAAATAATAALAERWWRRRGTGRTVPTSHGRLHVREIGDGPATLLLHGIHTSSDLWRPVLPHLARHGHRVLAPDLLGFGRSDKPAPGRYRIADQADRLAELLDALGIERCHLVGHSLGGTVAIEAAARHPERVASLTLLAPVTTGTLGGGLPAGALRALARSPLRLPLPAQQALWTTVTRTPLGRAAMRAAVLSRRAPRWLVDECCRQSALCRPATVVECFRASLTHTVEDLLPRITTPTTIVHGTADALIPLAESRRLAELIPNATLTELPGVGHLGMVEHPQAVADALTTGIRAAR"
    },
    {
        "reference": "MDLTTTSHARVDSGGVPFTSSLNDPTPPKLSASIALPAHLHLLAKAYGIPESHILQLAWALAANEQNARTAQWEHLELDERQAISWVLRHWQDPSVHRYLSPDELRGDKHQIPATVMAVVEEYSLFQTLALTGSETEIGMCFHPSTEQPWLRVIWNPEGMLASSASRLTRALESALHAVFLTPHVKVGDLTLFSIWDHQQILQWNSHYPQATDRLVHELFKDVVDASPQANAVAAWDGELTYRELDRLSSRLSGRLQDEFGVQPETIVVLCFEKSVWAIVAMLAVVKAGGAFLHVDPQHPAVRHQAMVQTTAAKLVLCSARTRSIISASVPECTSLVIDRRAFSVEPDHVQHETLLSSQNLSPRNAAYVVCTSGSTGTPKAIVVEHASLSTSVDAQANAMEISSGSRVLQYAAYTFDVSVGDIFTALTHGACICIPSDWERSHDLAGAINRLNVNQACLTSTVASILSPAEVPGLEKLTLGGEPATRQCVDAWAEQVRLKNVYGPAECTVWCMIQPEVSRHISVSNIGHGIGARAWIVHPEDHDRLMPVGAVGELLIEGPLVARGYLNDSTRTDEVFLSQPPRWLESFGPTPSRSRFYKTGDLARYGPAGALLFEGRKDTQIKLRGQRIELSEIEYRLHRALSDQVATAVELAHPKGSTAPVLAAFITWDQGIDLQNVQNVTLDARQEFEELASRIKAEIEQALPSYMVPALFIPVQTLPLTTSGKLDRKSLRHFCSQCSHEFLKKLDDSSPADAAPKESANPAEENLARLWAQVLERKSESIRRGDNFLSLGGDSLAAMRLVNLAARDLRLTLTVADVFNSPILADQANLLRPLVQTKHIAPFELVTDGDLPIQDLMDSVAKQCGLTSDQVEDVYPCTPYQEEMVRDSLSGTRTQMGQEVIQLASDLDLSRYLSACARVFQRCPILRTRFVEISGKLLQVVIREDISWQRPTSLAAYIEADNQTPPTLGKPLARWALTEDSTHLVLTMHHAIFDGISLGQIFGAIYAVYQSIPLPQVNLTFATFIGKIYRPHHDLPDASKQFWRSYLSPTAGSNDAPLSDVERASRPCANSGTQRLVTFQAGAVKALQQHGLTEATLARAAWACTLARGRQSPDSDVIFGTILTGRNIHLPGVDALAAPALAHTPIRVRMAAAQQEKPAHFLARVQADATAMIPFEHDGMDRIRALDEQVRVACDNMRTLLVIQPIPEGLILDSKSPFPGTMLSGPRVEAREMRHFHWYGLLMECTLLPMDGFFVRMSFDDTLYSPEAAERLLDEYSQTLHELAHGLTVDGSTE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016874",
                "GO-Name": "ligase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 791,
                "End": 806
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 759,
                "End": 836
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 759,
                "End": 832
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 758,
                "End": 831
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 765,
                "End": 836
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 768,
                "End": 831
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 189,
                "End": 618
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 241,
                "End": 641
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 865,
                "End": 1038
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 222,
                "End": 567
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 791,
                "End": 806
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 759,
                "End": 836
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 759,
                "End": 832
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 619,
                "End": 745
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 872,
                "End": 1286
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 369,
                "End": 380
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 758,
                "End": 831
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 765,
                "End": 836
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 768,
                "End": 831
            }
        ],
        "ipr_mapped": [
            45,
            29,
            46,
            30
        ],
        "response#1": "MIAERVKKIVVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLDNAAKKAPGRGRAPAVRLEAVALRRGPRRSAPPPPRRRAAAPPAPAPPPPAPAPPPPRRRAPRPRPARPRAPAGPSRRPPPPPLPPPTPLHAPPPPHPPPRRPPRRRRGRRPPARPRAPAHARRRAPRPRAPARRRTTAVRLEAVALRRGPRARAAPPARPRARARGREAEPDGELGQIENPMIAERVKKIVVEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLDNAAKKA",
        "response#2": "MSSAEIGERVKKIVVEHLGVDADKVTPEASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFLENAQKASVLRDRDCPRLPAEVAAFALSEDTARLRSGRRCARRPYRFSTPSRNTMSSAEIGERVKKIVVEHLGVDADKVVPEASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFLENAQKA",
        "response#3": "MSETAERVKKIVVEHLGVDADKVVDSASFIDDLGADSLDTVELVMAFEEEFGCEIPDDAAETILTFGDATKFLDKAAKSSDKQNVKPRNETNSLRSTSHTGSRFNRHDSSRPLSTSSNMKLHSMRVTGLNWKKNMSETAERVKKIVVEHLGVDADKVVDSASFIDDLGADSLDTVELVMAFEEEFGCEIPDDAAETILTFGDATKFLDKAAKS"
    },
    {
        "reference": "MNTQPLERALAAFREVLGTAHVSTDESARAAAETATFATTHRIPAIISPGSAAEVEACVRIAREHGVPLYPVSTGKNWGYGSRVPTSDGAIVLSLARMNRILDFNEELAYVAIEPGVTMRQLVAYLNDRGSRLMLSVTGSTPDSSVVGNICDRGFGAGVNAERIAHICNIEVVLPNGERLNTGFGRFPGAQTASIHRWGIGPQLDGLFTQSNLGIVTRMTIWLAPRPRHHEIFYFRLRDERRVEAVTDIIRDLKLQGLPRASVSLWNDYKLVSMKGQYPWQEAAGKTPLPEALLAKLRRAWGGAAWLGGGAILAASQDQIAAERAVIRKALHPHVDKLSFVGQRAARVARLLQRPVQRLTGFDLSEVVRAYEQSPHLGIPMERNIRSAYWRKKAPPPEQTDPDRDRCGAIWLAPAVPSTGKHVGTALRIVRERALAHAFEPGISVIFATERCANIVVALMYDRELPGEDGRAMACYQDIFDRLAAQGYLPYRLGIQSQSALPAAQSSYGTVVGALKRALDPDDILAPGRYDFRHEWPPADN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Oxid_FAD_bind_N, FAD-bd_PCMH that are essential for its biological function; 2. The protein should be classified within FAD-bd_PCMH_sub2, FAD-bd_PCMH-like_sf, FAD-bd_PCMH_sub1 sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,oxidoreductase activity,FAD binding,lyase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0071949",
                "GO-Name": "FAD binding"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004458",
                "GO-Name": "D-lactate dehydrogenase (cytochrome) activity "
            },
            {
                "GO-ID": "GO:0008720",
                "GO-Name": " D-lactate dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0071949",
                "GO-Name": " FAD binding "
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": " lyase activity "
            }
        ],
        "go_f_mapped": [
            4,
            4,
            255,
            32
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006094",
                "InterPro-Name": "Oxid_FAD_bind_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 45,
                "End": 182
            },
            {
                "InterPro-ID": "IPR016169",
                "InterPro-Name": "FAD-bd_PCMH_sub2",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 100,
                "End": 227
            },
            {
                "InterPro-ID": "IPR036318",
                "InterPro-Name": "FAD-bd_PCMH-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 227
            },
            {
                "InterPro-ID": "IPR016166",
                "InterPro-Name": "FAD-bd_PCMH",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 226
            },
            {
                "InterPro-ID": "IPR016167",
                "InterPro-Name": "FAD-bd_PCMH_sub1",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 99
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016170",
                "InterPro-Name": "Cytok_DH_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 229,
                "End": 491
            },
            {
                "InterPro-ID": "IPR016164",
                "InterPro-Name": "FAD-linked_Oxase-like_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 221,
                "End": 530
            },
            {
                "InterPro-ID": "IPR006094",
                "InterPro-Name": "Oxid_FAD_bind_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 45,
                "End": 182
            },
            {
                "InterPro-ID": "IPR016169",
                "InterPro-Name": "FAD-bd_PCMH_sub2",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 100,
                "End": 227
            },
            {
                "InterPro-ID": "IPR036318",
                "InterPro-Name": "FAD-bd_PCMH-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 227
            },
            {
                "InterPro-ID": "IPR016166",
                "InterPro-Name": "FAD-bd_PCMH",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 226
            },
            {
                "InterPro-ID": "IPR016167",
                "InterPro-Name": "FAD-bd_PCMH_sub1",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 99
            }
        ],
        "ipr_mapped": [
            736,
            737,
            738,
            742,
            401
        ],
        "response#1": "MAQSPATAPSATSSTSPPPASTTASAPSTAPPPTSSPAASSSPSATASASPSTSTTTASSPTRTSPSAPAAAPPAAAASSPPPSSTAAPSPALAPAASTSPSAAPSSAPSPTPAAPATTASSSPTPPTSSLSPSSTTSPPPPPPPSSTPTSAAATPASAPAPSPSPPSSTPASSPTSSPAPPPPAAPHSSVSAAPPSPPAPTAPAPPASPSTATTPPPPPPSTAPTTATPSATSTTTTTTPTPQSPSSPAAPSSSFTSTTTTTSTSPTASTTAAPPAAASATAAPSSATSTTASTTPPPTAPTAAAAPTSSTTTTAPTSSTSTKAASASSAPTAAASTAAPPASPATSTAAATATTTASAPAATASASASTPSAPA",
        "response#2": "MHPHTATLRPRSPRALRARPSTAPPPTPPPPPPPAPPRDAPKPPPPPPSPPQPPPNKAPPPPPPSAPAPAPAPAPAPAPAPAPAPAPAPAPAPATNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTRGVAARGGPARGVPARGVPARVVARGVPARGVPARGVLARVVARGVPARGVPARGVPARGVPARGVLARVVARGVPARGVPARGVPARGVPARGVPARGVLARGVPARGVPARGVLARVVARGVPARGVPARGVPARGVPARGVPARGVPARGVPARGVPARGVLARGVPARGVPARGVPARRGVPARGVPARGVPARG",
        "response#3": "APAHRVAEIALRAGIGGFHFYYGIPGTIGGGLRMNAGAYGVESRDRVVEVRAIDREGKVHVLSNRDMGYSYRHSSVPEDLIFTSALFEGTPADPAAIRAEMDRVQHHRETVQPVREKTGGSTFKNPPGTSAWKVIDEAGERGLRIGDAQVSELHCNFLINTGNATARDLETLGETVRRRVLENSGIRLEWEIKRLGVFREGEVIETI"
    },
    {
        "reference": "MQKLLSLPSNLVQSFHELERVNRTDWFCTSDPVGKKLGSGGGTSWLLEECYNEYSDGATFGEWLEKEKRILLHAGGQSRRLPGYAPSGKILTPVPVFRWERGQHLGQNLLSLQLPLYEKIMSLAPDKLHTLIASGDVYIRSEKPLQSIPEADVVCYGLWVDPSLATHHGVFASDRKHPEQLDFMLQKPSLAELESLSKTHLFLMDIGIWLLSDRAVEILMKRSHKESSEELKYYDLYSDFGLALGTHPRIEDEEVNTLSVAILPLPGGEFYHYGTSKELISSTLSVQNKVYDQRRIMHRKVKPNPAMFVQNAVVRIPLCAENADLWIENSHIGPKWKIASRHIITGVPENDWSLAVPAGVCVDVVPMGDKGFVARPYGLDDVFKGDLRDSKTTLTGIPFGEWMSKRGLSYTDLKGRTDDLQAVSVFPMVNSVEELGLVLRWMLSEPELEEGKNIWLRSEHFSADEISAGANLKRLYAQREEFRKGNWKALAVNHEKSVFYQLDLADAAEDFVRLGLDMPELLPEDALQMSRIHNRMLRARILKLDGKDYRPEEQAAFDLLRDGLLDGISNRKSTPKLDVYSDQIVWGRSPVRIDMAGGWTDTPPYSLYSGGNVVNLAIELNGQPPLQVYVKPCKDFHIVLRSIDMGAMEIVSTFDELQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLLAAIPAGSGLGTSSILASTVLGAINDFCGLAWDKNEICQRTLVLEQLLTTGGGWQDQYGGVLQGVKLLQTEAGFAQSPLVRWLPDHLFTHPEYKDCHLLYYTGITRTAKGILAEIVSSMFLNSSLHLNLLSEMKAHALDMNEAIQRGSFVEFGRLVGKTWEQNKALDSGTNPPAVEAIIDLIKDYTLGYKLPGAGGGGYLYMVAKDPQAAVRIRKILTENAPNPRARFVEMTLSDKGFQVSRS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Ribosomal_Su5_D2-typ_SF sharing conserved structural features; 2. The protein must be able to perform the nucleotide binding,nucleotidyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016779",
                "GO-Name": "nucleotidyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005524",
                "GO-Name": "ATP binding "
            },
            {
                "GO-ID": "GO:0050201",
                "GO-Name": " fucokinase activity "
            },
            {
                "GO-ID": "GO:0016779",
                "GO-Name": " nucleotidyltransferase activity "
            }
        ],
        "go_f_mapped": [
            61,
            122
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR020568",
                "InterPro-Name": "Ribosomal_Su5_D2-typ_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 583,
                "End": 776
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR052203",
                "InterPro-Name": "GHMP_Kinase-Related",
                "InterPro-Type": "FAMILY",
                "Beg": 24,
                "End": 948
            },
            {
                "InterPro-ID": "IPR006204",
                "InterPro-Name": "GHMP_kinase_N_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 692,
                "End": 768
            },
            {
                "InterPro-ID": "IPR036554",
                "InterPro-Name": "GHMP_kinase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 795,
                "End": 925
            },
            {
                "InterPro-ID": "IPR020568",
                "InterPro-Name": "Ribosomal_Su5_D2-typ_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 583,
                "End": 776
            },
            {
                "InterPro-ID": "IPR001174",
                "InterPro-Name": "HddA/FKP",
                "InterPro-Type": "FAMILY",
                "Beg": 589,
                "End": 604
            },
            {
                "InterPro-ID": "IPR001174",
                "InterPro-Name": "HddA/FKP",
                "InterPro-Type": "FAMILY",
                "Beg": 888,
                "End": 907
            },
            {
                "InterPro-ID": "IPR013750",
                "InterPro-Name": "GHMP_kinase_C_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 846,
                "End": 927
            },
            {
                "InterPro-ID": "IPR012887",
                "InterPro-Name": "GDP_fucose_pyrophosphorylase",
                "InterPro-Type": "DOMAIN",
                "Beg": 64,
                "End": 429
            }
        ],
        "ipr_mapped": [
            387
        ],
        "response#1": "MKIENKEIYEKLLNINKININNEEIKLEEINNEILNKELIEIEESKIEEENKIENLKIIIKEEINKKEKIKYINENKIENNEKNIIQEIKNKNIEIKEIEYIKNENKEFILKLENENNKNKIEKIDENKLKIKENNIYKINENIEIKKEEEILINNININNLNLENIEKINNINNLKNIIKFIGEEENEINLIEFEIEDIIEEKINKINNYLNKEIEEIINKEINQKEEINNIKNNLKNIKKIKKELKNKEIINIEEELEKKNNIEIENYLISKNLL",
        "response#2": "MPREELRRRLEALSPAERDRLLEEAERLLREREDAEAAARRLGVPPEAAEALARALAEVEEAARRGLLSPEEAAPLRARLREVLREAGVEPPPEARRPLAPPPPPPPPGEAERLLERLEEEARRALAEAEERGEAPARELRRAVRELRERLPPPPPPRERLRRALEDALALAEALREALPPGAPPEEALRRAAEELYRAMPPPEREALREAVRRASL",
        "response#3": "MEKIENIKKEEEKYIKIKEIERYKEIENNIDEYIEGNIIENKLNNIEIEEIKNKINIEEILNEEINIKEIEENKIKSLLKNIENIINYNKINEKNNKINIDYDNIKLEINNKNIENIEEKINNKIEKEVINKINNINNNIKEYNINEKENLDNLIENNIIEINYNKNNNEINIEIMDEKNKEYIKNIIEEIFEIKEIKEKESKKKEENKELKIEIKKNIIEKIIKKNELFEEIN"
    },
    {
        "reference": "MASYPKKKCGVLGATGSVGQRFILLLADHPFLELHAIGASNRSAGKKYKDAVRWKQTTAMSERLSNLVLRDCRADQFSDCDLVFSGLNSDVAGEIEMEFIKAEIPVFSNAKNYRKHPLVPLVVPTVNPQHLDLIPHQRKEFGLKKGFLVCNSNCAVIGVVIPFAALQAKFGPVEEVEVFTEQAVSGAGYPGVPSMDIMDNVIPYISGEEDKLENEAQKILGSLNADATAFDEQKGLTVGATCTRVGVTDGHMAFVSLRFKNRPGPSAEEVKQAMREYQSEAQKLGCPSAPREAIKVFDEPDRPQPRLDRDISKGYTVSVGRVREAAPGSYFDLRFAALSHNTVIGAAGSSILNAEVAVIKGYI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Semialdehyde_DH_NAD-bd, Semialdehyde_DH_NAD-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,NAD binding,NADP binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": "NADP binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004073",
                "GO-Name": "aspartate-semialdehyde dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": " NAD binding "
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": " NADP binding "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            4,
            22,
            23
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 132
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 171
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 132
            },
            {
                "InterPro-ID": "IPR051823",
                "InterPro-Name": "ASADH-related",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 363
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 171
            },
            {
                "InterPro-ID": "IPR005676",
                "InterPro-Name": "Asp_semi-ald_DH_pep-lack",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 357
            },
            {
                "InterPro-ID": "IPR012280",
                "InterPro-Name": "Semialdhyde_DH_dimer_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 165,
                "End": 343
            }
        ],
        "ipr_mapped": [
            42,
            7
        ],
        "response#1": "MDELRVAVAGASGYTGAELVRLLAAHPHLRLTALTARPGSATAGRPLAELVPDLPPVPVAPADDPAALDALVAAADVVFGALPHHLAEPTARAVRAAGRRYLDLSAAYRLAPTVPLYVPEVNPAHAAELHARGGVTSRAARGGRGRRPRPGRPRVHPGPGRRHARPRAELRGGSGRRPAAPGRRRRARIATALPGARPHADTTADTAATTATTDTGDTGDTADTGGTARRNRSVAPSYTPHEPKIRAALARLAPDTAPDTLTFTPHLVPMTRGIMTTLYARLTEPVTVDEARAAYEAAPGVRVLDVPPDAPLPTTADVLGSNHTTVALHQVPGTRLLTVVSVLDNLLKGAGAPAVQNANIMAGLDETTGLTHTPVLP",
        "response#2": "MDVAIVGPGRIGTRLLDDLAASDTLSVGSVVGRDPDAAGIAAARERGVPTTADGLDGFLGADVPADVVFDATAAYVHADNAAPYRDAGTRLVDLTPAARGAEFVVPPVDLADVDDRENVNMVTCGGQATIPLVSAVAAVTDPDYLEITAVHSVADAGPGPGTVDNISETTRGTARAVAEVGDAERGTLVFNPLTDGTLMRDTLYVVPAADPDRDAVREAVRATVREVYGYEFTL",
        "response#3": "MTDEPTRVAVVGATGRVGAAVAERVADDPELTLAAAFARPGSDVAARHPALADVPVTDTDPAAAFDAADVVVDATPAPVAVDLAARAADAGARYLDLTDPRADDTAGTTGVVDWAAVADRPALTVAAPGSAAATAAVGAVADAAAPRLETLEVTATVARSPVGRDHIADARAVAAADVRDRVDGDRSAADSVTTDRDADADTDAVGRATVTHAAGPPTTTRATVSVVPAAAGDVPGDGADASSVDVPSVDVPSVDVPSVDVPSVDVPSVDVPSVDVPSVDVPDVPSVDVPSVDVPSVDRYRVTTTVTVPDPPPTTTATTDAAVAAARAVAAETGVAAVDE"
    },
    {
        "reference": "MAGVEEADKLKQLGNAAFSERKWHLAIDMYTKAIELTKTPTLFCNRALAELRAELPGAALADADAALGIEPTFAKAYYHKASAYLSLGKHKQALTNYKKVVDLAPQNSDAQAKVEFCKKEIRRINFENAIMTPDEAPLSQTIKLGSVRADYDGPRIENETVTVEFVEAMKEHFRLEKLIDRHDVIFILLEVQKILKKCPNFVSINVPVGEEITVCGDTHGQYYDLLNIFKLNGNPLETNRYLFNGDFVDRGSYSFENIMTLFAYKVLYPDHFFLSRGNHEGVSMNRMYGFEGEVTQKYNSEMFRLFTEVFNSLPIGHIINNEVFVVHGGLYSSDKVTLDDLQHPNRFRDIPESGLICESLWSDPQPMPGRAPSKRGVSCLSFGPDVTETFLNNNNLKLLVRSHEVKDEGYEIEHGGKCITVFSAPNYCDQMGNKGAFIRFTGGDMKPRFTTFTHVPHPGKRPMHYATGFGLF",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Calcineurin-like_PHP_ApaH that are essential for its biological function; 2. The protein should be classified within Metallo-depent_PP-like, Metallo-depent_PP-like sharing conserved structural features; 3. The protein must be able to perform the cation binding,hydrolase activity,hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            },
            {
                "GO-ID": "GO:0016791",
                "GO-Name": " phosphatase activity "
            },
            {
                "GO-ID": "GO:0004722",
                "GO-Name": " protein serine/threonine phosphatase activity "
            }
        ],
        "go_f_mapped": [
            183,
            19,
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 132,
                "End": 470
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 161,
                "End": 467
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 212,
                "End": 406
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR011990",
                "InterPro-Name": "TPR-like_helical_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 133
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 132,
                "End": 470
            },
            {
                "InterPro-ID": "IPR019734",
                "InterPro-Name": "TPR_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 74,
                "End": 107
            },
            {
                "InterPro-ID": "IPR051134",
                "InterPro-Name": "PPP_phosphatase",
                "InterPro-Type": "FAMILY",
                "Beg": 41,
                "End": 466
            },
            {
                "InterPro-ID": "IPR019734",
                "InterPro-Name": "TPR_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 7,
                "End": 40
            },
            {
                "InterPro-ID": "IPR019734",
                "InterPro-Name": "TPR_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 41,
                "End": 73
            },
            {
                "InterPro-ID": "IPR041753",
                "InterPro-Name": "PP5_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 151,
                "End": 467
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 161,
                "End": 467
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 212,
                "End": 406
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 179,
                "End": 456
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 395,
                "End": 415
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 241,
                "End": 268
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 338,
                "End": 365
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 308,
                "End": 334
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 417,
                "End": 433
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 211,
                "End": 238
            },
            {
                "InterPro-ID": "IPR006186",
                "InterPro-Name": "Ser/Thr-sp_prot-phosphatase",
                "InterPro-Type": "DOMAIN",
                "Beg": 274,
                "End": 298
            },
            {
                "InterPro-ID": "IPR013235",
                "InterPro-Name": "PPP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 115,
                "End": 202
            },
            {
                "InterPro-ID": "IPR011990",
                "InterPro-Name": "TPR-like_helical_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 131
            }
        ],
        "ipr_mapped": [
            641,
            643
        ],
        "response#1": "MPPPPPPPPPAAAAAAAAAAAAAAAAAAPPPPAAAAPPPPAAAAPPPPAAAAAAAAAAAAAPPPPAAAAPPPPPPPPPPPPPPPPGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGRRRRRRRRRRRRRPPPPPPPRRRRGGGGGGGGGGGGAGGGGGGAAAAAADDDDDDDDDDDDDDDDDDDDDDDDDGGGGGGGAAAAAAAAASSSSSSSSSSSSSSSSSSSPPPPPPPPPPPPPPPAAAAAGGGGGGGGGGGGGGGGGGGGGGGRRRRRRRRRRRRRRRRRRRRRGRRRRRRRRRRRRRRRRRRRRRRRGGRRRRRWRRRRRRRRGRRRRRRRPPPPPPPPPPRRLRGGIACLLRW",
        "response#2": "MAAAAAAAAAAAAAAAAAAAPPPPPPPTAAAAAAAAAAAAAAAAAAAAAAAAAAPPPPPPPPPPPPPAAAAAAAAPPPPPPPPPPPRRRRRRRRRRRRRRPPPPPPPPAAAAAAAAAAPPPPPRRRRRRRRRRRRRRRRRRRRRRPPPPPPPPPPPSSSSSSSSSSSSSSSSSSSSSSSSSSGGGGGGGGGGGGRRRRRRRRRRRRRGGGGGGGGGGDDDDDDDDDDDDDDDDDSSSSSSSSSSSSSSSSSSSSSSSSEEEEEEEEEEE",
        "response#3": "MNNINNKKIYYKKNIYIKKKKKYNINININLKYIKKNINYIYVFKKKYYNNKKINNIKTKYKKIKKFINYKKKYYNNNNIYFIKKKYKKYNKYYYYNIYNYNIIYDKNNNNINLYKKKYLNNINKYSKKINKNINIYINIYETQIYKYNYIYINYNNKIYIYLNIYNYIINIVNIYNIYYIIKKTYIYNYIYKIINNIIYNIINKNIIKKKTIYNNTIYIKKYIKYINYINKKYSNIYKIYNITKKKNINILYKKMFKNIQKNNYIIYNKYIYNN"
    },
    {
        "reference": "MKLLKILSLVCLSISIGACAEHSMSRAKTSTIPQVNNSIIDQNVQALFNEISADAVFVTYDGQNIKKYGTHLDRAKTAYIPASTFKIANALIGLENHKATSTEIFKWDGKPRFFKAWDKDFTLGEAMQASTVPVYQELARRIGPSLMQSELQRIGYGNMQIGTEVDQFWLKGPLTITPIQEVKFVYDLAQGQLPFKPEVQQQVKEMLYVERRGENRLYAKSGWGMAVDPQVGWYVGFVEKADGQVVAFALNMQMKAGDDIALRKQLSLDVLDKLGVFHYL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Beta-lactam/transpept-like, Beta-lactam/transpept-like sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity,organic acid binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043177",
                "GO-Name": "organic acid binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008800",
                "GO-Name": "beta-lactamase activity "
            },
            {
                "GO-ID": "GO:0008658",
                "GO-Name": " penicillin binding "
            }
        ],
        "go_f_mapped": [
            19,
            203
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 55,
                "End": 272
            },
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 38,
                "End": 280
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 55,
                "End": 272
            },
            {
                "InterPro-ID": "IPR001460",
                "InterPro-Name": "PCN-bd_Tpept",
                "InterPro-Type": "DOMAIN",
                "Beg": 66,
                "End": 268
            },
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 38,
                "End": 280
            },
            {
                "InterPro-ID": "IPR050515",
                "InterPro-Name": "Bact_Transpept/Beta-Lactamase",
                "InterPro-Type": "FAMILY",
                "Beg": 53,
                "End": 161
            },
            {
                "InterPro-ID": "IPR002137",
                "InterPro-Name": "Beta-lactam_class-D_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 81,
                "End": 91
            }
        ],
        "ipr_mapped": [
            492
        ],
        "response#1": "MRPAPPPPAPPPPPPPPPPPPPPPAPPPAPARRAAAPAAAAAAAAPAPPPPPLPPPPPPPAAAAAAAGRGRRPARRRAARAGGGAGPAARRRAGRAGRRRRAAAGCAAGGGGGGGAAGGAAAAAAAAGGGAGRGGAGGGGAAAAAAAAGGGGRRGGRRRRGRPPPAPPAGRRRRAAGGAPGGGRRRRGRRRGGAAGGAAAGAAPPPPPPPPPPPPPPPPPPPAAAAGGGRGRGRRRAAGGGGGGGRGRRRRARDRRGRRRRGGGGRRRGRGGGAAGGGGGAGGGRARGRGGRRRRA",
        "response#2": "MTTTPTTTPPPTTTPPPPPPTPPTTTPPTTTPPTPPPPPPPTPPPTTPPTTTPPTPPPTPPTPPTPPTPPTPPTPTTPPTPPTTPTTTTPPTTPTTTTTTTTTTPTTTAATATAAAAAAAAAAAAAAPAAAAPPPPPPPPPPPPPPQQPQQQQQQQQQPQQQQQQQQQQQQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQQQQQQQQQQQQQQAAAAAATATATAAATAAATAAATAAATAAAAATAAAATAAATAAATAAAAAAAAAAAAARRRRRRRRRRRRRRAAAAAVAGGGGGGGGGGGGGGGGGGGAAAGGGGGGGGTGGGGGGGGGKEEEEEEEEEEKEEEEEEEEEEEEEEEEE",
        "response#3": "PPRPRRPPRARPRPPRPPRPPPPRPPAPPPRPPPPPRRPPPPRPPGRRRRARRRRRRRARPPPPPPPPPPAAAAAAAAAAAAAAAAARRRRPAPPRAAAAAARARAAAAAARAAAARAPAAARGRPAAGAAAAPAAAGGGGGGGGGGVGGDGGGGGGGGGGGGGGGGGGGVGAAPGGGGGGGGGGGGGGGGGGGGAGGGDGAGGAAAAAAGGGGGRRRQRRVRLWAAWARRRPRRPRRRRPRPPPPRRPRRRRRPPPPPRPRRPPPPRQAPPPQPPPPPPAAAPAAPAAAAAPPAAGRAAAAARPRRRRRRRRRRRGGGGGGGRRRRGRGGGGAA"
    },
    {
        "reference": "MTLQETSVLEPTLQGTTTLPGLLAQRVAEHPEAIAVAYRDDKLTFRELASRSAALADYLEHLGVSADDCVGLFVEPSIDLMVGAWGILNAGAAYLPLSPEYPEDRLRYMIENSETKIILAQQRLVSRLRELAPKDVTIVTLRESEAFVRPEGTEAPAARSARPDTLAYVIYTSGSTGKPKGVMIEHRSIVNQLGWLRETYAIDRSKVILQKTPMSFDAAQWEILSPANGATVVMGAPGVYADPEGLIETIVKHNVTTLQCVPTLLQGLIDTEKFPECVSLQQIFSGGEALSRLLAIQTTQEMPGRALINVYGPTETTINSSSFPVDPADLDEGPQSISIGSPVHGTTYHILDKETLKPVGVGEIGELYIGGIQLARGYLHRDDLTAERFLEIELEEGAEPVRLYKTGDLGQWNNDGTVQFAGRADNQVKLRGYRVELDEISLAIENHDWVRNAAVIVKNDGRTGFQNLIACIELSEKEAALMDQGNHGSHHASKKSKLQVKAQLSNPGLRDDAELAARPAFDLEGAEPTPEQRARVFARKTYRFYEGGAVTQADLLGLLGATVTAGYSRKAADLAPAELGQILRWFGQYISEERLLPKYGYASPGALYATQMYFELEGVGGLKPGYYYYQPVRHQLVLISEREATGKATAQIHFIGKKSGIEPVYKNNILEVLEIETGHMVGLFEQILPAYGLDIHDRAYEPAVKDLLDVADEDYYLGTFELVPHAGARDDQAEVYVQTHGGKVAGLPEGQYRYENGELTRFSDDIVLKKHVIAINQSVYQAASFGISVYSRAEEEWLKYITLGKKLQHLMMNGLNLGFMSSGYSSKTGNPLPASRRMDAVLGANGVDSAPMYFFVGGRISDEQIGHEGMREDSVHMRGPAELIRDDLVSFLPDYMIPNRVVVFDRLPLSANGKIDVKALAASDQVNAELVERPFVAPRTETEKEIAAVWEKALRRENASVQDDFFESGGNSLIAVGLVRELNARLGVSLPLQSVLESPTIEKLARRLEREVAQESSRFVRLHAETGKARPVICWPGLGGYPMNLRSLAGEIGLGRSFYGVQSYGINEGETPYETITEMAKKDIEALKEIQPAGPYTLWGYSFGARVAFETAYQLEQAGEKVDNLFLIAPGSPKVRAENGKVWGREASFANRGYTTILFSVFTGTISGPDLDRCLETVTDEASFAEFISELKGIDVDLARRIISVVGQTYEFEYSFHELAERTLQAPISIFKAVGDDYSFLENSSGYSAEPPTVIDLDADHYSLLREDIGELVKHIRYLLGE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within AB_hydrolase_fold, ACP-like_sf, ACP-like_sf, AB_hydrolase_fold sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the lyase activity,oxidoreductase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            32,
            4,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1012
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 967,
                "End": 982
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 937,
                "End": 1012
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1009,
                "End": 1276
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 936,
                "End": 1009
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 931,
                "End": 1016
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1019,
                "End": 1282
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 945,
                "End": 1008
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1012
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 455
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 967,
                "End": 982
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 379
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 937,
                "End": 1012
            },
            {
                "InterPro-ID": "IPR000415",
                "InterPro-Name": "Nitroreductase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 538,
                "End": 723
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 425,
                "End": 509
            },
            {
                "InterPro-ID": "IPR020459",
                "InterPro-Name": "AMP-binding",
                "InterPro-Type": "DOMAIN",
                "Beg": 164,
                "End": 175
            },
            {
                "InterPro-ID": "IPR020459",
                "InterPro-Name": "AMP-binding",
                "InterPro-Type": "DOMAIN",
                "Beg": 176,
                "End": 184
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1009,
                "End": 1276
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 169,
                "End": 180
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 936,
                "End": 1009
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 931,
                "End": 1016
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1019,
                "End": 1282
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 16,
                "End": 424
            },
            {
                "InterPro-ID": "IPR001031",
                "InterPro-Name": "Thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 1030,
                "End": 1138
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 839,
                "End": 930
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 945,
                "End": 1008
            }
        ],
        "ipr_mapped": [
            35,
            45,
            46,
            29,
            30
        ],
        "response#1": "RIGVPDPITRDTDFVNDLGIDSLDTVELVAAIEEEFDIEIPDEAAAVDDIQTVGDVVDFIVELIDHPADQIEVTAKVPERRIDIDQLTAIASITIDAKPLPDDVKSSEPVRYEIKSRDEIEALIRDIVVDRLGVGVPDPITRDTDFVNDLGIDSLDTVELVAAIEEEFDIEIPDEAVDDIQTVGDVVDFIVELIDHPADQIEVTAKVPERRIDIDQIEVTAKVPERRIDIDQLTAIASITIDAKPLPDDVKSSEPVRYEIKSRDEIEALIRDIVVDRLGVPDPITRDTDFVNDLGIDSLDTVELVAAIEEEFDIEIPDEAVDDIQTVGDVVDFIVELIDHPADQIEVTAKV",
        "response#2": "MSETGGLSPAEIAERVRKIVVAHTGVDPDKVTIESTFVDDLGFDSLDTVELVVAIEEEFGIEIPDDAAETIFTVQAAVDYITSHASTIEKLGLSPAEIAELRAGCMSETGGLSPAEIAELRAGCMSETGGLSPAEIAELRAGCMSETGGLSPAEIAERVRKIVVAHTGVDPDKVTIESTFVDDLGFDSLDTVELVVAIEEEFGIEIPDDAAETIFTVQAAVDYITSHASTIEKLGRLYI",
        "response#3": "VVDQLGVDDEVTVDTFVDDIGADSLDTVELVVAFEDEFGVEIPDEAIPDEAADDIQTVRDVVDNVRGLESGDDSERSSEDSQDSENSENSEDSQDSENSENSEDSQDSENSENSEEVSEESSSEEEVSEESSSEEEVSEESSSEEEVSEESSSEEEVSEESSSEEEVSEESSSEEEVSEESSSEEEVSEESSDEEIFDRVKAIVVDQLGVDDEVTVDDTFVDDIGADSLDTVELVVAFEDEFGVEIPDEAADDIQTVRDVVDYVRGLESGDDSERSSEDSQTSQ"
    },
    {
        "reference": "MRHIGVFVGVLALALVLLVVEARSDAERGVCACPRIYMPVCGSNLKTYNNDCLLRCEINSDLGRANNLRKIADQACDNLTDNVNDFIPQEY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Kazal_dom, Kazal_dom, Kazal_dom, Kazal_dom that are essential for its biological function; 2. The protein should be classified within Kazal_dom_sf sharing conserved structural features; 3. The protein must be able to perform the serine-type endopeptidase inhibitor activity,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004867",
                "GO-Name": "serine-type endopeptidase inhibitor activity"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004867",
                "GO-Name": "serine-type endopeptidase inhibitor activity "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            3,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 29,
                "End": 76
            },
            {
                "InterPro-ID": "IPR036058",
                "InterPro-Name": "Kazal_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 76
            },
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 25,
                "End": 78
            },
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 30,
                "End": 76
            },
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 56
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 29,
                "End": 76
            },
            {
                "InterPro-ID": "IPR036058",
                "InterPro-Name": "Kazal_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 76
            },
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 25,
                "End": 78
            },
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 30,
                "End": 76
            },
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 33,
                "End": 56
            },
            {
                "InterPro-ID": "IPR053265",
                "InterPro-Name": "Serpin",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 61
            }
        ],
        "ipr_mapped": [
            376,
            377
        ],
        "response#1": "MKTLCLLFVLFSFCVSLSAEGFQFGEKKVPRPLCFLPKEVGRCGAHFPRFYYNFNSGRCERFIYGGCGGNNNNFDTEQACRASCASFQFGEKKVPRPLCFLPKEVGRCGAHFPRFYYNFNSGRCERFIYGGCGGNNNNFDTEQACRASCASFQSAEGFQFGEKKVPRPLCFLPKEVGRCGAHFPRFYYNFNSGRCERFIYGGCGGNNNNFDTEQACRASCASFQSAEGFQFGENAEGFQFGEKKVPRPLCFLPKEVGRCGAHFPRFYYNFNSGRCERFIYGGCGGNNNNFDTEQACRASCASF",
        "response#2": "MKAAAALLLLLLLLLSVSAAQQQQQQGSPVEQSHSLCLLPAKPGNCSAGFERFYFNPRSRRCEKFIYGGCGGNPNNFKTIGECNDACRNSKQGSPCEQSHSLCLLPAKPGNCSAGFERFYFNPRSRRCEKFIYGGCGGNGNPNNFKTIGECNDACRNSKQGSPMKAAAALLLLLLLLLLSVSAAQQQQQGSPVEQSHSLCLLPAKPGNCSAGFERFYFNPRSRRCEKFIYGGCGGNPNNFKTIGECNDACRNSK",
        "response#3": "MGRCYSRSNYEAGCGCNSRGCSRHGQDSYDACLNFCKDPEGGDCNYQYWRDGSQYKDIYSSGRCYSMGRCYSMGRCYSRSNYEAGCGCNSRGCSRHGQDSYDACLNFCKDPEGGDCNYQYWRDGSQYKDIYSSGRCYSMGRCYSRSNYEAGCGCNSRGCSRHGQDSYDACLNFCKDPEGGDCNYQYWRDGSQYKDIYSSGRCYSMGRCYSMGRCYSRSNYEAGCGCNSRGCSRHGQDSYDACLNFCKDPEGGDCNYQYWRDGSQYKDIYSSGRCYSMGRCYSRSNYEAGCGCNSRGCSRHGQDSYDACLNFCKDPEGGDCNYQYWRDGSQYKDIYSSGRCYSMGRCYARSNYEAGCGCNSRGCSRHGQDSYDACLNFCKDPF"
    },
    {
        "reference": "MGLSHSGEIVYIHPSSPVDLFTTCASLPTKPPPSFSDMPSPLFLVSGFLGVCVAYAVANIIRQLLFPNAKEPPVVFHWFPWLGSALTYGKDPYKFLFAARAKYGDVFTFVLLGRNVTVHLGVAGNDFVFNGKETHMNAEEIYGPLCNPVFGEGVVYDCPNSKLMEQKKFVKFGLTTDALKAHVRLIEHEVVNYIKSSRDFKGPSGVINVPPVMAQITIFTAAIALQGPEVRSKLTNEFASLYHDLDGGFSPINFVLPHAPFPHNIKRDRAQLKMRKIYEAIIAERRAGKIPPTTDMISHLMQCSYKNGRPIPDSEISNMMITILMAGQHNSSNIASWIMLHLANEPQLCEELYQEQLDQLADEHGNLPELELHTVEKLKLHSSVVKETLRMHNAIHSIMRLVKQPLPVPNTSWTVPPGHAVLASPGVSANSNEYFLNPTKWDPHRWDDRVIEEDDESEMVDYGYGRTSRGTKSAYLPFGGGRHRCIGEKFAYLNLEVITAVMVRNFRFKNVDGRVDVPGTDYSTMFSRPLEPAEICWERR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 469,
                "End": 485
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 317,
                "End": 343
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 72,
                "End": 89
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 413,
                "End": 427
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 485,
                "End": 503
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 94,
                "End": 117
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 429,
                "End": 447
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 378,
                "End": 394
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 478,
                "End": 487
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 76,
                "End": 536
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 65,
                "End": 540
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 326,
                "End": 343
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 476,
                "End": 485
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 485,
                "End": 496
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 383,
                "End": 394
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 69,
                "End": 540
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 469,
                "End": 485
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 317,
                "End": 343
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 72,
                "End": 89
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 413,
                "End": 427
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 485,
                "End": 503
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 94,
                "End": 117
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 429,
                "End": 447
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 378,
                "End": 394
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 478,
                "End": 487
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 76,
                "End": 536
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 65,
                "End": 540
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 326,
                "End": 343
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 476,
                "End": 485
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 485,
                "End": 496
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 383,
                "End": 394
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 69,
                "End": 540
            },
            {
                "InterPro-ID": "IPR050529",
                "InterPro-Name": "CYP450_sterol_14alpha_dmase",
                "InterPro-Type": "FAMILY",
                "Beg": 53,
                "End": 532
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "MEVLGVHQYLSANRFMRWRLTSFFSLPDVVTKTLTRALNRLTVPLSEETSFALKKEWTDSKEWHEVSLKETVLRIVAQLSSRVFVGPELCRNEEWLKITTDYTVDSFTAAEELRLWPEILRPVVHWFIPSCRRLRKQVAEARAIINPVIEARRSAKNGTYNDTIEWFEETAAGRSYDPALAQLSLSVAAIHTTSDLLTQTLLDLCARPELIQPLREEIVKVLRENGGWKKTALYNLKLMDSVLKESQRLKPVAVVTMRRIATENVTLSDGTFIPKGTKVAVSAHAMWDASVYENPEEFDGYRFVRMREQPGKENSAQLVSTSPDHLGFGLGKHACPGRFFAANEVKIALCHILLKYDLKLVESAKPRAVNSGIFLLADPSAKVMVRRRKEEISLVE",
        "response#2": "MDIFRFTGIPGFEAFQIEADDNEILQDAVTKNLTRALNTLTEDLSEETSFALRKEWTDSKEWHEVNLHETVLRLVAQLSSRVFLGPELCRNEEWLDITTNYTVNSFVAAEELRLWPELLRPVVHWFLPSCRKLRADLARARAIINPVIEERRRAQADPSSKKYNDTIQWFDEVAAGRSYDPAVAQLSLSVGAIHTTSDLLTQVLFDLCARPELIQPLREEIIRVLKSEGWKKTALYNLKLMDSVLKESQRLKPVGVVGMRRIATEDVKLSDGTLIPKGTKIAVSAHKMWDPDKYPDPEKFDGYRFVKMREVPGQENSAQLVSTSPDHLGFGLGKHACPGRFFAANEVKIALCHILLKYDIKLVDGAKPEAVNAGILLFADPTAKVMVRRREEEI",
        "response#3": "MTDIPGFEAFKVRDIHSDITHDVVTKQLTRALNRLTEPLSEETSFALKKHWTDSKEWHEVSAKETVLRLVAQLSSRVFLGPELCRNEKWLNITVNYTVDVFTAAEELRLWPEILRPIVHWFLPSCKKLRAQLAEARAIINPVLEERRRMKEQARAEGRQVPRYNDTIEWFEEIAKGRSYDPALAQLSLSVAAIHTTSDLLTQVMFDLCARPELIQPLREEIIRVLREHGWKKTALYNLKLMDSVLKESQRLKPVALVTMQRMVMEDVTLSDGTFIPKGTKVLVSAHKMWDPAVYPDPEKFDGYRFVKMREQPGQENSAQLVSTSPDHLGFGLGKHACPGRFFAANEVKIALCHILLKYDFKLVDGAKPKNVSSGIFVLADPTAKIMVRRREEEIS"
    },
    {
        "reference": "MSILWIVAYALLAFAASIALNLVYQFLYRTFNKSRPPLVFHWVPFIGSTIHYGMDPYNFFFSCREKYGDIFTFILLGRPTTVYLGTQGNEFILNGKLKDVNAEEVYSPLTTPVFGSDVVYDCPNSKLIEQKKFIKFGLSQAALEAHVPLIEKEVIDYLAQSPNFNGTAGTVDIASAMAEITIFTAGSTLQGEEVRSKLTTEFAVLYHDLDKGFTPINFMLPWAPLPHNKKRDAAHARMRAIYIDIINKRRKAGNAATGKPDMIENLMQCTYKNGQPLPDKEIAHIMITLLMAGQHSSSSIGSWIMLRLASQPAIVEELYQEQLANLERTANGSLPPLQFKDIENLPLHQNVIRETLRLHGSIHSLLRKVKNPLPVPGTPYIIPTSHVLLSAPGVTALSDEYFPNAMAWDPHRWETQAPEESKEDIVDYGYGAMSKGTSSPYLPFGAGRHRCIGEKFAYLNLTVIVATLVRHLRFHNLDGKKGVPGTDYTSLFSGPLKPTRVGWERRAAKSA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 451
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 451,
                "End": 462
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 350,
                "End": 361
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 506
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 444,
                "End": 453
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 58,
                "End": 81
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 451,
                "End": 469
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 396,
                "End": 414
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 380,
                "End": 394
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 345,
                "End": 361
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 451
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 53
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 283,
                "End": 309
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 511
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 40,
                "End": 480
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 451
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 451,
                "End": 462
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 350,
                "End": 361
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 506
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 444,
                "End": 453
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 58,
                "End": 81
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 451,
                "End": 469
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 396,
                "End": 414
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 380,
                "End": 394
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 345,
                "End": 361
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 451
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 53
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 283,
                "End": 309
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 511
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 40,
                "End": 480
            },
            {
                "InterPro-ID": "IPR050529",
                "InterPro-Name": "CYP450_sterol_14alpha_dmase",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 499
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "MNIHRDVVTAKLTRALNTLTIPLSEETSFALKTEWTDSREWHEVPLHETVLRIVAQLSSRVFLGLELCRNEEWLKITTNYTVDAFTAAEELRLWPEFLRPLVHWFLPSCRKLRKQVAEARAIINPVLEERRRDPQAEKYNDTIQWFEETAKGRTYDPALAQLKLSVAAIHTTSDLLSQVLFDLCAHPELIQPLREEIIAVRGGINKTALYNLKLMDSVLKESQRLKPVNVVGMKRKVIAKEGVTLSDGTFLPKGTKISVAAFAMGRDPAIYSDPEKFPDPDRFDGYRFVKLREVPGQENSAQLVSTSPDHLGFGHGKHACPGRFFAANEVKIALCHILLKYDIKFMDGSKPKATNLGIFLYADPSAKIMVRRREEE",
        "response#2": "MLTFKEFEGVEGTYNFHQEILVDAVTKNLTKALNVLTGALSEETSFALKKDWTDSKEWHEVSLQETMLRLVAQLSSRVFLGKELCRNQQWLDITINYTVDSFTAAEELRLWPFFLRPIVHWFLPSCRRLRKQLADARAIINPVLEARRNSKDQPYNDTIQWFEDTAKGRSYDPALAQLSLSVAAIHTTSDLLTQVLFDLCANPELIQPLREEIVKVLREHGGWKKTALYNMKLMDSVLKESQRLKPVNVVTMRRMVKEEVTLSDGTKLPKGTKVVVAAHKMWDADIYPDPDKFDAYRFVDPSRAQYVSTSPDHLGFGLGKHACPGRFFAANEVKIALCHILLKYDIKLVDGAKPESTGNGFFLIADPAAKIMVKRREEEISLE",
        "response#3": "YPEEFEPERIAHRQLALSFAAIHTSSMTVTHAMFDLCARPEYIQPLREEQIQVLKETNGEWNKTALYKMKLMDSFMKESQRLNPPVLVSMFRRVVKEGITLSDGTFLPKGTRISVPAYAMNHDEKIYEDPFKFDGFRFVRTAGSSSQFVSTSPSHLGFGHGRHACPGRFFAANEVKIALCHILLKYDFKLVEGERPKNVNKGFNILADPSARVLVRRRKEEIQ"
    },
    {
        "reference": "MHQLKKLITVKVIGSGEKTVVLGHGFGTDQSVWKHLVPYLVEDYRVVLYDNMGAGPTNPDYFDFERYASLEGYAYDLLAILEELQIDSCIYLGHSLSSMTGVIASIFRPDLFSKLIMLSASPRFINADDYYGGFEKEDIDQLSQAMDTNYKSWIEGFAPLVIGGDMDSVAVQEFSRTLFNMRPDIALSVFRTIFTFDLRHFLCRVTVPCHIIQSSKDLAVPVAVSEYIHQNLGGKSIVEVISTEGHLPQLSAPEVTIPVLLRHISHDITSNAAP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AB_hydrolase_1 that are essential for its biological function; 2. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 270
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 252
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 264
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 270
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 252
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 264
            }
        ],
        "ipr_mapped": [
            35,
            36
        ],
        "response#1": "MPPATRPRPRAAAAAATTAAAATAAAAARRRARRRRAAAAAAGWTPPGATERTVPGPDGPLTVVERGAGPDVRLLLHGLGLSWRCWELLPPPPGTRWLAPDLRGFGRSPKPADDAYTPARHAADTAALLDALGVGRCHVVAHSLGTFVAADLAARHPDRLASLVLVSPATRAPLPRPPRRRHAAAPRGTAPPPPPRPPAPPPPPRHPPRRAAALARAAPRHPARAALALAAAATRPARTARATAALADNALVTRTLVPRYTSGRATPAALAFITEQSRRCDPRTTVRCLRALARHDVTAALARIAVPTLVLHGTDDQLIPVECGRRTAELIPGAEYRELPGCGHMLPLERPEEVHAALTAHWERTTGRTAR",
        "response#2": "PPPPPRPPPSPPPSPPPPPPPPPPPPPPPPPPPPPPPPPPSPPPPPPPPPGGRYIELPRGRLFVRVYGEGPEAVVLLHGLGATSRIWEPLVPHLARRFRVLAPDLLGHGRSDKPTDPALYTIEAFVEDLAALLDALGVERAHLVGHSMGGAIAMAFPLRYPERVASLTLIGTGARLRVAPGILEALRRDYARALDLLVQYAFAEDAPPEVVERVREEFLRVPPEVAYADFVACDYFDVMERLGEVRVPTLVIAGTRDLLTPPRYARFLAEHIPGARLVVVEDAGHLVMLEKPEETARLIAEFIEGAARG",
        "response#3": "MTTTTVPAAGGPIAVETLGGGPDAVLLLHGLFTSRRSWELTLAPALAARHRLLLPDLRGHGESPAPTDPAAYRIADHAADAAAVLDAAGAARCHVVGHSLGGMVALELAAGHPERVASLTLISAATGLSLAGAAADLPPRTWRTLAQATARHPYAAGAAFAALLRRRPDTVARALAAVSRTGAYVTEAMTRSATAGAATPELLRHCLEQSRRCDPRTLGDCLHATAHHDVTAALARVDVPVTLLAPTDDPLAPPAATRRLAALLPAGAARLRELPGAGHLLPLERPQETAAAITETWERTR"
    },
    {
        "reference": "MAPLQPGDSFPANVVFSYIPPTGSLDLTVCGRPIEYNASEALAKGTSVLVAVPGAFTPTCQEKHVTGFIAKLDQLRQAGVDRVLFIASNDAFVMSAWGKANGIKDESILFLSDSDTAFSSSIGWANAGRTGRYAIVVKDGKVVYAAVDTVRGSTEKSGVDAVLTVLGNQGKL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Thioredoxin_domain that are essential for its biological function; 2. The protein should be classified within Thioredoxin-like_sf sharing conserved structural features; 3. The protein must be able to perform the cation binding,peroxidase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0004601",
                "GO-Name": "peroxidase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            },
            {
                "GO-ID": "GO:0008379",
                "GO-Name": " thioredoxin peroxidase activity "
            }
        ],
        "go_f_mapped": [
            183,
            113
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR013766",
                "InterPro-Name": "Thioredoxin_domain",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 171
            },
            {
                "InterPro-ID": "IPR036249",
                "InterPro-Name": "Thioredoxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 166
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013766",
                "InterPro-Name": "Thioredoxin_domain",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 171
            },
            {
                "InterPro-ID": "IPR037944",
                "InterPro-Name": "PRX5-like",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 164
            },
            {
                "InterPro-ID": "IPR037944",
                "InterPro-Name": "PRX5-like",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 163
            },
            {
                "InterPro-ID": "IPR013740",
                "InterPro-Name": "Redoxin",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 163
            },
            {
                "InterPro-ID": "IPR036249",
                "InterPro-Name": "Thioredoxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 166
            }
        ],
        "ipr_mapped": [
            185,
            186
        ],
        "response#1": "SAAAPPPSPPPPPPPPPPPRRRRRPPPPPPPRRPPPPPPPEPPPPPPAAAAAAAPPPPPRRRRRSSSSSSSPSPSSSSSSSAAAAAAAAAAAAASSSPPSSSSSSSAAAPSPPRRRRRYRRRRRRRRAAAPPPPFAATAPPPPPPPPAAAPPAAAAAAADAADVAAAAAVAAAAAAEASPSTSSSSRRRSSRRRRRGSQSSIAAQFRYSVCVRNSCSIVTFSIRRQVRETSWTTALRLHAELDGAANSTLEQKSSSVGAKASSSSSTLLRSKYYRVGSNITSK",
        "response#2": "MAAAAAAASSAAAASASAAASSAAASASAAAASTSSSSSSSWWPPRRAAAAAATTTTTTAAAARSLRQLPPPSSSSSSSSSTSSSSSSSSSSSSSSSRRRGRRGGGGRRTVCCSEVVKVTKDTFADEVLKSELPVVVDFFATWCGPCKMIAPFLEKLAVDYQGKLKVLKVDVDECQDVAAEYNVRCMPTFQFFKKGEKVDEFSGANPGKLKSTIDKLLQ",
        "response#3": "MNNNNNNENKDNKVDKEDNIKEEDNKENKVDINEDNKDNKEKEDKNKEDNKENNKEEDSKENKEDNIKEENEDIKEDIEDIMEENIENNKDNNKEDNKENKDIKEDKDIKEDKEDKIDNDKEENEDIKEDNIKEDKEDNEDNKEDNKDNKDVKDDKEENKENKDIKDDKEDKIDNDKEDNKENNNIKEDNNIKEENEDNIKEDIKDDVKEEDNKENKDNKEEDIKEDNKENKEDNIDDNKEDIKEENNNNKDENNIKEDNNNIKEDNNNNDNKEEENKEEENKDLNKEDNNLKEDKEDNIKDNIKEDNNKEENKEEENKEEDNNIKEDNKDIKEDNIKDDIKEDKEEEIKEENKDSEDKEENKDNKDNIKEDKEDNDKEK"
    },
    {
        "reference": "MTVKVRFDKEVREYAKGEKVKDSVLKITETALAQALEKFHRRMIVIEGDTLKKAELAGILAGASARVLSDIVGELIEKRLRDESEDKIEVLYATDALGEETFGRKRYEAFRKHFDVLAGSEVNVTAVTFKHTREILGRTYDLLILDMSYDYSPNDLGRIIETVRGGGLIFILAHPFEKWKDMWTGFHKSLVTPPYTIEDVKKRFNRRLIRKFTQHDGIYIITESGKAKKKPKKSKSQAKIRARKGVEIPEETLFPKELYEMALTRGQVEVLKAFEELVDKEGMLVLTADRGRGKSVSVGIAAIGLAVALKKRTRIVVTAPELENVQSLFRFAKRALEKLGFKPYVVEEKGLIKELYARKIGLRYYPPAEGYKKNADLYILDEAAGIHVPILHKYLNKPRVVYSSTIHGYEGAGRGFSVKFLKKAREKRSFKELHMEEPIRYAYGDPIEKWLFDVLLLDAEPVELTEEDYELIKRKEVYLEEPDLDDWFENDREDLRHFVGIYILAHYRNRPSDVALLADAPHHEARVLRLKNGKIVTAVQIAKEGGIPKNVIDKMAKGYKPRGNIIPDMMVKHHYLKEFARLKGYRIVRIATHPDAMDMGLGSKALELLEKEAREKGLDWIGSGFGASEELVRFWVRNGFAVVHLSPARNPVSGEFTAIVLKPISKKAKELIKKANDEFRIRFTEWLGDTHRELEPEIARWLFETPFGEAVDYPIHLTEIQKKRLDAFTGKVLTYDTVVDAVKPIVKLYFLDGWMKPYLDERQIKLLIYRVLQAHSWEETAKLIDRTEMFTMIEVRDIIRGLWYYYKRLLT",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the N-acyltransferase activity,nucleotide binding,N-acyltransferase activity,RNA binding,tRNA binding,N-acyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:1990883",
                "GO-Name": "18S rRNA cytidine N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            },
            {
                "GO-ID": "GO:0106162",
                "GO-Name": " mRNA N-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0019843",
                "GO-Name": " rRNA binding "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            },
            {
                "GO-ID": "GO:0051392",
                "GO-Name": " tRNA N4-acetyltransferase activity "
            }
        ],
        "go_f_mapped": [
            238,
            61,
            238,
            96,
            138,
            238
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 490,
                "End": 644
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 281,
                "End": 448
            },
            {
                "InterPro-ID": "IPR007807",
                "InterPro-Name": "NAT10/TcmA_helicase",
                "InterPro-Type": "DOMAIN",
                "Beg": 285,
                "End": 458
            },
            {
                "InterPro-ID": "IPR032672",
                "InterPro-Name": "TmcA/NAT10/Kre33",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 610
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 259,
                "End": 397
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 499,
                "End": 611
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 612,
                "End": 664
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 490,
                "End": 644
            },
            {
                "InterPro-ID": "IPR024914",
                "InterPro-Name": "tRNA_acetyltr_TmcA",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 806
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 474,
                "End": 663
            },
            {
                "InterPro-ID": "IPR013562",
                "InterPro-Name": "TmcA_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 221
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MGVEERAREAGELARELVGRVDEDAAEARRGRPRGRRRRGRGRAVAMREGAETGEGAREREGEGEGEGERRPARERAERGRERERGGEGARREEDRRAAEARGRVRADAGEGEAEEARDAPAEGEEGRRGGAAAGQEAGRAARAFEESEGEPDLEGEGGAGGEGEGERSGGDGQRGEEPGGADGGRERAGRGEGERRGIARAEEEAARLVAAGEAVAREAAEAEARRRRERAGTEEAVREAARGKGGVEAGGEEEEARAREAAARAEREEALRARGPARRREEGREGTRGV",
        "response#2": "MGDEGEREEERAERRRRAEERREGDGGAEAEKAAAERAPVEDGEAGSLDAEELRAAGEAREAGERGRDLGRLLELSRLGSAEEEAPRLEVVEAGEPRRTAAEVREAEERERARGEERAAMGEGGEPARAAAEGERRRPARRGGVRGEARRAAREREEAAERAGAEAREGEGEEACAAVEREGRGRVEESRRAGREGELERGSRGDRAAGEEEEAAAAERREREVPERAAELGERVEGREPGERRVSRVEREEGAGREGEAARGAYEEAGARPEEAAAGPERGTGERGREAEERAERDREGRERAGYVREARRPFPSEADALRVLRERGGEPEGAAAERLAEEPEAGVVEEGEERGR",
        "response#3": "MEGEEEGAGEGREREEAAAAERAKAGDAGGAGEDGEDRALERGARDARREQLRAGLGERERRRDGVDAGAARGRGRERREARGREAAGAGGGEGGGREGAAEEEAAREREAREAAEARRRREEEEGRARLGEGREEEERRRAEARHEGAEAEARREARRERERAERREREEARARVRAEEGEAAAPAEGAAVEGEGEAEGGADEGEGGEAEEEGRGGREGRRRVRGCARAEGRRARGGRREAGRAARGGREQERGGARGGARPGEAGERGEAGRAGERGGGEGGRRAGGAAGAVAGEAAGEAAGEEGLGEAGAGVAVEGVVR"
    },
    {
        "reference": "MSPRPQIKVGVLGATGTVGQRFIELLAAHPYFALHALGASSRSAGQQYARVVRWKLPSPIPDAVRHMVVHECRPDAPGFAECGVVFSGLDADVAGDIENAFRAADLVVYSNAKNYRRDPLCPLIVPLVNPSHLSIIPYQREQLGLKKGYIVTNANCSTTGIVVPLAALEKAFGPLDTVIVTTLQAISGAGYPGVSSLDIMDNVVPLISGEEDKIEWETNKILGGVTPDNKAFDLHAPKQINVSATCTRVPVIDGHTGCVSVKFARSPPPSVAEVENAFREYTCDAQHLGVPSAPAQAIVVHDAPDRPQPRLDKNLHNGACVSVGRIRECPVFDIKFVCLIDNVRLGAATSSIINAEIAVEKGLIQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Semialdehyde_DH_NAD-bd, Semialdehyde_DH_NAD-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,NAD binding,NADP binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": "NADP binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004073",
                "GO-Name": "aspartate-semialdehyde dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": " NAD binding "
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": " NADP binding "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            4,
            22,
            23
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 136
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 179
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR051823",
                "InterPro-Name": "ASADH-related",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 364
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 136
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 179
            },
            {
                "InterPro-ID": "IPR000319",
                "InterPro-Name": "Asp-semialdehyde_DH_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 242,
                "End": 256
            },
            {
                "InterPro-ID": "IPR005676",
                "InterPro-Name": "Asp_semi-ald_DH_pep-lack",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 359
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            },
            {
                "InterPro-ID": "IPR012280",
                "InterPro-Name": "Semialdhyde_DH_dimer_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 165,
                "End": 344
            }
        ],
        "ipr_mapped": [
            42,
            7
        ],
        "response#1": "MRIALLGASGYTGAELARLVLAHPRLELAAVVSRSTAGRPLADVHPRLADRTGVPVRTAEEALALDVDVAFCATPAAATREWLPRLRERGVRVVDLSGAYRVGGPAPRSRVPAAGTSAAPGGPANPTGRDRVPALRSHRRRPKGVPRLVLPPAAPAAPLPSPGRRRGPEALAAHVAGVRDPELLPVPDAPRRRRRSPAARPRRPAPAPVRRLLVPARP",
        "response#2": "MTTRVAIAGARGIVGAELVRLVDADPDLELVALTARSSAGRPAAEVVPHLADVPLITDFDTDTAAAAADVVFDATGVFVHADAAPRYRAAGVRVVDLSAAARTVPYFVPGVNLDAVAGQDDIVNVTCGGQATVPLVHAVSRATPVEYAEIDIVAATSSVTAAGKKNLADLRAASTNIIPTSTGAAKAVGKVLPETAGKLTAHAVPVPTPNIMRDTVTCRLAEPVDAAAVEAAVRATVADTPGVRYLDGPPVLDGDRVTVYLEVEGAGDYLPSYAGNLDIMTAAALTVARRLAAQTTTTTTEATT",
        "response#3": "MTAPTVAVAGATGSVGTELVRLLAAPDSPLRLALVTGSRTAGRRLADLHPHLAHLATDVPVLPPEECVAAADVVFLALPAPDAAVLAPRLRAAGRHVLDLSGADRTPGTPGAPAGAPAAAGTPGADGAPDADDGPPAARAAALLAAAVPLLEEAVGRPETTVVDVVRAPGPRPGPPALRRLRELLGPAVTGAVAHRTDAPGVLRTTVTCRLTRPPDPDAVAEAVRTAAADEPGVELLEPPRVTPGPDGTTVTVHVRTRVPDHLPRHAGNLDIMTAAALRTARRLAAPRPPRP"
    },
    {
        "reference": "MALVRFATIITVLCHLAIQDGAAKSFPHGEKAPFPLTLIHINDLHARFDETNQKSSTCTNSKECIAGIARVYHTIKQLKSEYKTKNPLYLNAGDNFQGTLWYNLLRWNVTAYFIKELPPDAMTLGNHEFDHSPKGLAPYLAELEKMKIPTVVANLEKNGEPALKDSKIARSIVLKVGNRKVGVIGALYDKTHLVAQTGMVTLTNSIEAVRKEAQELKKKNVNIIVVLSHCGLDGDKQLAEEAGDLIDVIVGAHSHSLLLNKDAKVPYDTKYDTIEGDYPLVVKKSNNHTVLITQARSFGKYVGRLTVNFDCEGEVQSWEGYPIYMNNSVKQDEEVLRELEPWRAEVKRLGTQVIGTTEVFLDRESCRWCECTLGDLIADAYADQYTNSTVQPVAFVQAGNFRNPIEKGDITNGLAIEAAPYGSSVDMIKLSGADLWSAIDHSFTLDDEFRYNTAQVSGMAVVADLSKKPYERVQSIDIVGANGAKTALKKDQIYYVVVPSYLADGKDGFAMLKKGTNRVTGPLDSDVLIEYVRKRQTIAKTMFQEKRVVIENHTNGTCSWDLDSQRYKPK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Calcineurin-like_PHP_ApaH that are essential for its biological function; 2. The protein should be classified within Metallo-depent_PP-like, Metallo-depent_PP-like sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity,pyrophosphatase activity,cation binding,nucleotide binding,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0016462",
                "GO-Name": "pyrophosphatase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008253",
                "GO-Name": "5'-nucleotidase activity "
            },
            {
                "GO-ID": "GO:0004050",
                "GO-Name": " apyrase activity "
            },
            {
                "GO-ID": "GO:0008047",
                "GO-Name": " enzyme activator activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": " nucleotide binding "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            19,
            341,
            183,
            61,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 350
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 256
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 349
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006146",
                "InterPro-Name": "5'-Nucleotdase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 119,
                "End": 130
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 350
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 25,
                "End": 551
            },
            {
                "InterPro-ID": "IPR008334",
                "InterPro-Name": "5'-Nucleotdase_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 353,
                "End": 513
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 256
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 349
            },
            {
                "InterPro-ID": "IPR036907",
                "InterPro-Name": "5'-Nucleotdase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 352,
                "End": 542
            },
            {
                "InterPro-ID": "IPR036907",
                "InterPro-Name": "5'-Nucleotdase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 353,
                "End": 552
            },
            {
                "InterPro-ID": "IPR006146",
                "InterPro-Name": "5'-Nucleotdase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 36,
                "End": 48
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 487,
                "End": 506
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 52
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 219,
                "End": 236
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 239,
                "End": 262
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 409,
                "End": 432
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 290,
                "End": 310
            }
        ],
        "ipr_mapped": [
            641,
            643
        ],
        "response#1": "MDFEEELMPEELEDLSEKEWYGDDYFWFPSYWWAEDDYMDDKYDVWSMVFEYENYEDAYTVQSELEYEEYEEDQEYGIDQMCEWFMDHMWEEYEKFLVYEGDMNEEWHFEEDHDDDEKHHEHTYMYDVGGHYEYGHKYPEVEDEEDYEDYEFKFDWYGYKAIGWYCGDHIYDEWDYWDEARQYCMDEDYKDWESMYEYEYEDEDDSYSEKDEWDDYRESFIYWDERASDYEECYEEWFMEYMDMHQKCYGDDEYDYDEEYDELEWWADPDVEGHPAKDHNKLERYM",
        "response#2": "FRRRRGGRSRGGRAGGEPGGRRRGGDDGGRRDDGDAGGGDRRRDGRERGRGDDDDGEDDRGRGGDAGPEGADVGDAGHGLGEDGDEERDDRERDDERREDEGGEGDDEDAHDAGDADEAEDERRAEERRGQAERRRREEDGREEAREGEGGEEEYERDGDDEEGGESRDAGDDAADREEAGPRREEPWRPLHDDEGDGDGDSRAAREDEPREGLDGKERRENERCRGRTRWREGDR",
        "response#3": "MACDCDAPQGMLDELPVTEMTNEEMSAQVTCDVSEGAVSNYHENLGLTSEMEHEGRAGRDICGRPACTGDDDPRRDYDETADEGDQWDEAEGDYDDGDWYMDGPMEFEHEDEEDGARGWCWETCEEEECGEWDREEMEDEYDDDEYAHEGYYCDEERRVRFVEDHYEIDYEEERDETDPPEGPWHDEDYDERAYEDAEDEEIDEDLTTTDYWECEDVSDCEKDADDEHWVPVGRWQYRW"
    },
    {
        "reference": "MYSKYVIIISLLAVVSLGSAIEFWNPEECGCPPFDKTENEVCTKHGTTYDNRCQFDCHQKFLSKSGVALEEGPCILSAEAEEEAKK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Kazal_dom that are essential for its biological function; 2. The protein should be classified within Kazal_dom_sf sharing conserved structural features; 3. The protein must be able to perform the toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity "
            }
        ],
        "go_f_mapped": [
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 23,
                "End": 76
            },
            {
                "InterPro-ID": "IPR036058",
                "InterPro-Name": "Kazal_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 74
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 23,
                "End": 76
            },
            {
                "InterPro-ID": "IPR036058",
                "InterPro-Name": "Kazal_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 74
            }
        ],
        "ipr_mapped": [
            376,
            377
        ],
        "response#1": "MKLLLLLPVLALLVSFSSSEECCQKDCNDCKNKNCENKDKNCKENCDNKENKNCEKNCKNENKNYEDKNSKDCKNKNCDKNNNCDKECTDCEKNCNNENKNCENNDKNCEKNCNNENKNCKENCENKDCGNCENKECKKCDCNNNCCKECTNCEKDCKNENKNNCDKNNCNCDKCNKSCKDCNKENCDNKNKNCKENCKKNKNCKECKKCDKDCKNCKIKCKENCKNDDCKKCKKKCKDCKNDECKKCDKDDCNCNKDECKPFTDAQESCES",
        "response#2": "MKIFFVFFLLFVKDCYSGKGDYDCKDKDGKKCDEYCKKNYSSEPDKTSCPEDCDFSDCECKDDNGKFFSSCLCGKKKDGKKKYCSCDCSDCLKWKDCYSGKGDYDCKDKDGKKCDEYCKKNYSSEPDKTSCPEDCDFSDCECKDDNGKFFSCLCGKKKDGKKKYCSCDCKDKDGKKCDEYCKKNYSSEPDKTSCPEDCDFSDCECKDDNGKFFSSCLCGKKKDGKKKYCSCDCKDGKKCDEYCKKNYSSEPDKTSCPEDCDFSDCECKDDNGKFFSSCLCGKKKDGKKKYCSCDCSDCLKWKDCYSGKCDYDCKDKDGKKCDEYCKKNYSSGPDKTSCPESCDFKDCTCIKKESGINCICSCNTKCQESGKSCSDSCKK",
        "response#3": "MKSFLLLSIFPVIFLTFLATSEDCNTSCNCKGECKEKEDCKDCDCKENGFFYDNRCCTKDGKCVCKDYFCQKFCGDDGCKEECKCYCSTDDCTCNCKGECKEKECCKDCDCKENGFFYDNRCCKDCDCKENGFFYDNRCCTKDGKCVCKDYFCQKFCDDGCKEECKCYCSTDDCTCNCKGECKEKEDCCKDCDCKENGFFYDNRCCTKDGKCVCKDYFCQKFCGDDGCKEECKCYCSTDDCTCNCKGECKEKEDCKDCDCKENGFFYDNRCCTKDGKCVCKDYFCQKFCGDDGCKEECKCYCSTDDCTCNCKGECKEKED"
    },
    {
        "reference": "MTTSSDSAMVNHTPSPWYKFGFKSFAEFNTYVTFVFLGMSIMMVASAVTSAPDFLTRYYVYATGDPDAVAETPLFWNNANTFYNAGTYVLQVLTELFSLTPFMRRIPLSVRLFVGLGIPFAELLLIIIVPAATIKSQHGAIAVIMVVACVGGFSKALCDSCTNALVGPFPTKFMNGAQWGLTVIALLMSIIQIILKVSMGTSFHDILTMSRIYFGICIGIQLFAIFELAILRFNPFAQKYIAEYRAGAQRNAQNNESTLEETAPSMNEPAAGDIADLPATVDDKERALNEEEGDEVRAVTSEEFHVKRGAVLTATGDADKMVDLDQTGNITSTEQLLRASAASVFKRVYPMLVCVFLIYFTSLLTFPGVFFLVSTTSGWYMTVIVTLFNAGDFISRMVLMFRPLRPSPKVVVAGTLGRLIIIPFLVLCVRGIIRGEALPYVLITLLGLTNGYFGCMACIHCPRTTTLRYAGERSLAAMLSGISIMLGLCFGSNLSLAITLTH",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within MFS_trans_sf sharing conserved structural features; 2. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005337",
                "GO-Name": "nucleoside transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 99,
                "End": 492
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 27,
                "End": 498
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 146,
                "End": 498
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 99,
                "End": 492
            }
        ],
        "ipr_mapped": [
            34
        ],
        "response#1": "MNATRVVGPGVAGALFALARAVPFAVDAASFAVSVAALLLLPRTPAPPPAPARRPLRREILEGLRFVVRNPHLRTIAAQTAVFNLFDNFYYALFALFVLRRLHLSPGAYGLVLAAGGVGSVLGALVAPWAARRLGTGRALVASGAVLGTGLLLLPVASGLPPAAAVCVVALASAVAGFSVVVYNVLQVSYRQAMTPDHLLGRMNATVRFVVWGTMPLGALAGGALAAAVGVRPAAVLGAIGFVVSLAVVARSPLRRLREVPEPVEAEAA",
        "response#2": "MQGQPAAAQPVAAQTQPAQAQPQQTQPAQTQPAQTQPAAAQPAQTTPVQPQPQATTTAPAQTQPQPQTTATAQTQAATQPTQTVPAQTTPVQPQPAPVQPQPQTTAPAQTQPAQTVPAQTTPSQPQPQPAPAQPAPTQAAPAAAQPATVQPQPQTTAPAQTAPAAETAAPAEQPAPASTTDSAPATEAPAPAEDSSSTDTSSEASTPETSTSADSSSVA",
        "response#3": "MTTTTPPADTPAAPNPTRTIAALALGGITFALLQTLVVPLLPQLPELLHTDAANASWIVTATLLSGAVATPVITRIADMYGKRRMILVCVVLMVAGSLVCALSTTLALVIIGRALQGLGMGVVPIGISIMRDELPRERVGGGVAMMSSTLGIGAAVGLPLSGVIAEYLSWHSLFWISAAISVLAFLAVFFGVPESPVRDRSALRRFDLRGLILLVPALVSLMLVVSKGRDWGWPGWVWALLALAVAAFAGFVILELRAENPMVDLRLFRNRTFTAASVASFCLGAALGFV"
    },
    {
        "reference": "MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQDNRLLVEEIGPYASQSAGKEYYKHIEKIIVDNDVYEKSLEGERTFDINYQGIKINADLIKDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKTVPQNQGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGTVYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQIHFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKDSYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQGAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSYIRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQVETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKHAKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLSSNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEKALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVLDLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVSPKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVSVEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLTGEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRALNQKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKMLGYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKLIEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENSHLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKAEKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIVALGFIIGRKTLFK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should include a EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 2. The protein must be able to perform the cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            }
        ],
        "go_f_mapped": [
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 532,
                "End": 544
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR037250",
                "InterPro-Name": "NEAT_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 363,
                "End": 495
            },
            {
                "InterPro-ID": "IPR037250",
                "InterPro-Name": "NEAT_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 969,
                "End": 1120
            },
            {
                "InterPro-ID": "IPR006635",
                "InterPro-Name": "NEAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 369,
                "End": 501
            },
            {
                "InterPro-ID": "IPR006635",
                "InterPro-Name": "NEAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 978,
                "End": 1128
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 617,
                "End": 638
            },
            {
                "InterPro-ID": "IPR011432",
                "InterPro-Name": "Shr-like_HID",
                "InterPro-Type": "DOMAIN",
                "Beg": 205,
                "End": 269
            },
            {
                "InterPro-ID": "IPR006635",
                "InterPro-Name": "NEAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 976,
                "End": 1129
            },
            {
                "InterPro-ID": "IPR006635",
                "InterPro-Name": "NEAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 976,
                "End": 1138
            },
            {
                "InterPro-ID": "IPR050333",
                "InterPro-Name": "SLRP",
                "InterPro-Type": "FAMILY",
                "Beg": 550,
                "End": 971
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 713,
                "End": 771
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 569,
                "End": 626
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 641,
                "End": 700
            },
            {
                "InterPro-ID": "IPR037250",
                "InterPro-Name": "NEAT_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 372,
                "End": 501
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 736,
                "End": 757
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 532,
                "End": 544
            },
            {
                "InterPro-ID": "IPR032675",
                "InterPro-Name": "LRR_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 496,
                "End": 818
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 734,
                "End": 757
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 760,
                "End": 781
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 663,
                "End": 686
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 710,
                "End": 733
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 568,
                "End": 590
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 639,
                "End": 662
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 591,
                "End": 614
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 687,
                "End": 709
            },
            {
                "InterPro-ID": "IPR003591",
                "InterPro-Name": "Leu-rich_rpt_typical-subtyp",
                "InterPro-Type": "REPEAT",
                "Beg": 616,
                "End": 638
            },
            {
                "InterPro-ID": "IPR006635",
                "InterPro-Name": "NEAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 371,
                "End": 497
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 569,
                "End": 590
            },
            {
                "InterPro-ID": "IPR001611",
                "InterPro-Name": "Leu-rich_rpt",
                "InterPro-Type": "REPEAT",
                "Beg": 641,
                "End": 662
            },
            {
                "InterPro-ID": "IPR006635",
                "InterPro-Name": "NEAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 368,
                "End": 495
            }
        ],
        "ipr_mapped": [
            67
        ],
        "response#1": "MSPRRRPPPPPAPPPAPPPAPPPPDERAARLLALAAEEAERLREEGRREAERLREEGRAEAERLRAEARAEAEELRRRAEEEAEELRRRAEEEAEELRRRAEAEAAEVRAEAERLRAEAEELRARAEAERDRLLAEAEARRREAAEEAARLREEARAEAERLVRDARAEAERLVRDARAEAERLRAEAERRAEEVEREAEERAERLRAEVRELEERRERVRALLAELGPPPPPPPPPPPPRRPPDPDPDPPPPPRRPPPDPDPPDPDPDPPPDPDPDPPDPDPDPDPPPDPDPDPPDPRRRPRRPS",
        "response#2": "MIKLHTWPTPNGWKVTIALEELKLPYERVDLDLGAGEQRTPEFLALNPNGKVPVIEDDGFTLCESNAIMRYLARKHGGDGLWPADARAQAEVDEWLDWQVGSLHPHINQSTWFNRFTPEVPRTADTDESEAMNAKLAALDAALAARPAEPRERLAAIREKLTARRDAIAAELAASPEAPPAAAPAASAAAGGKPFYRSIAMGEHTPYAVNRYINETRRLFGVMDARLARTPYLVGDAYSIADMSCYPWVLRFRRFGVDVLDGYPNVAAWLERVEARPAVQRALALEEAFAAEPAAPAPHAAE",
        "response#3": "MKKISKNALSLSLVALLAFSLTSCKKEETTTNNTTTTTTTTETKKEEPKKEEKKEEKKEEPKKEETTTTKTETKTETTTTTTTTEPKKEEPKVVELSNIYFDFDKSDIKPESKSELDKVVEFLKANPNVSIEISGHTDNIGSKEYNLKLSENRANSAKNYLVSQGISSDRLSTVGYGEEKPIADNSTAEGRAKNRRVEFKVTDKAKAEAEKAAASK"
    },
    {
        "reference": "MKSLIGTLGLYCLFILTNNVVSSYGDDLYPLTIMHTNDFHARFEETNVKGNPCKSGEKCIGGLARVLHTIKKIIKEQEKKNIESLYINAGDNFQGTIWYNIGRWNVTSELMNIQPPDVMVLGNHEFDHGIDGLLPFLNNMDKTEIVVANMDARDEPQVAKKIKPFTIIKKKYRNIGVIGVVVEEVPDLANTGKLKFRNESEAILEAARNLKKEDPSVNIIIVVSHVGFDVDKIIAERTGSEVDIIVGGHSHTVLYTGTPPGPEKPEDNYPYVYNHPSGNKVLVVQAVCHAKYVGNLTVFFDKKGKVVTYEGAPIYMDTKVEQDKDVLEAMKPWRKLIDEKTKLVVGRTNVDLPRDICRSEECALGNLYTDSMIYAFGGKENCKSGSTWTTAPIAFVHAGAMRSSLHQGDILYSDALLLSPFTNMVVAYDLPGAQLKAALEFSAAPKNEDEKRRFLQMSGLKVTYNMSRAANNRIVDLKVRTNVCPYDQYENLDEKKTYRVVSPSFLQGGGDGFKMLRDYAKNIQNQKIDLDALVDYLKKFSPLAPKAEGRITIIH",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Calcineurin-like_PHP_ApaH that are essential for its biological function; 2. The protein should be classified within Metallo-depent_PP-like, Metallo-depent_PP-like sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity,pyrophosphatase activity,cation binding,manganese ion binding,nucleotide binding,toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0016462",
                "GO-Name": "pyrophosphatase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0030145",
                "GO-Name": "manganese ion binding"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008253",
                "GO-Name": "5'-nucleotidase activity "
            },
            {
                "GO-ID": "GO:0004050",
                "GO-Name": " apyrase activity "
            },
            {
                "GO-ID": "GO:0005178",
                "GO-Name": " integrin binding "
            },
            {
                "GO-ID": "GO:0000287",
                "GO-Name": " magnesium ion binding "
            },
            {
                "GO-ID": "GO:0030145",
                "GO-Name": " manganese ion binding "
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": " nucleotide binding "
            },
            {
                "GO-ID": "GO:0090729",
                "GO-Name": " toxin activity "
            }
        ],
        "go_f_mapped": [
            19,
            341,
            183,
            39,
            61,
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 341
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 338
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 32,
                "End": 252
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 341
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 29,
                "End": 553
            },
            {
                "InterPro-ID": "IPR006146",
                "InterPro-Name": "5'-Nucleotdase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 116,
                "End": 127
            },
            {
                "InterPro-ID": "IPR036907",
                "InterPro-Name": "5'-Nucleotdase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 344,
                "End": 554
            },
            {
                "InterPro-ID": "IPR006146",
                "InterPro-Name": "5'-Nucleotdase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 31,
                "End": 43
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 338
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 409,
                "End": 432
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 491,
                "End": 510
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 29,
                "End": 47
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 235,
                "End": 258
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 281,
                "End": 301
            },
            {
                "InterPro-ID": "IPR006179",
                "InterPro-Name": "5_nucleotidase/apyrase",
                "InterPro-Type": "FAMILY",
                "Beg": 215,
                "End": 232
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 32,
                "End": 252
            },
            {
                "InterPro-ID": "IPR008334",
                "InterPro-Name": "5'-Nucleotdase_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 344,
                "End": 517
            }
        ],
        "ipr_mapped": [
            641,
            643
        ],
        "response#1": "MPPRPRRPGGEDDADVHGAERALGHGRRTRATAGGAGAPGAPGRGAAALPAAAGRRARRAADRDRDRAGRPVRHPDRPARGRHDGRGAGPAPPGGQRGGPAAGGARPAPAVGAADAGPVGGAAGDEAGPPDRCGRPRRGAARGDGLGDAADGGGRAPVGREARRGTSRARAPPARGRGPPGGRPRHCAGRRGDDRAGRRRAAAAPGGRRGPGPPGASAAGAGAPLALAGGTARAARAAAGRPAGGGPARAPTQDPCSGAVAARAWPARGRAGRRPVAHPGPARAAADDPAEPVRRPRAAARPDRRPPGAAAAAAAGPREARARA",
        "response#2": "MPAGRPARVGPRARAPPGPAAGAGPGGAGPLPGCGRAGGPPGPSPAAGRGPTAGAPGRGGARAGRAARRPDRRERPPRGALADPGPRAGRAPGAPAGGARPASSRARTGDDDPAPPGAPGAAGAAEHRRRRGGAARAAGPAGARPPRGGRPGARPPAAAAAGPGPACPFAAGERLVRRPARAAHPRRSPAARGRPPRPGLGPCWTSGPHR",
        "response#3": "MARPGAPGPAGAAPAAPRARPRPRAAGAGPGAGRGVDRPAGGDAAGERHRDRDDGAPGAGATRADPYRVDEPGRRRGGGGAAGAPDGEAAGRADHGADGAAGGADDRDDRRPRRAAGAGDDGGRGAAAGDADAAADRYGPDGDDDDGGDRDRGRRRPDADAAYRHHRAPDRDRPAADGRAAAPGAADRDAGAADGPDRGAAAAAAGDRRRRRPPDAGRRAAGAGPRGRGGPRAGPGRAPAARPPPGGGPGRPAAAGAAGDRRGPAARGARHAGGRPPGRAARPRGDTPRRGPRRAGGPAGAPPARARTRG"
    },
    {
        "reference": "MGRVTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAARTFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNMPDPIPVIILARLAVDLSFHGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIHHGFKSSQTQQRTLFLRLPQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016747",
                "GO-Name": "acyltransferase activity, transferring groups other than amino-acyl groups "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 147
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 146
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 147
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MSSSTSSAAPSPSSSRPPSPSADERRVRRDARERRSALRERLDALLEAIDERRAALDELRRNPALADAAAPLALERRHRALALLDAWLERDLPRALREDPRCVAALDDQLLRLERAIDPPLDAPREDAPPALPPRTGALLDELAQVLIDADRAQRRLFAGDDPDADPRVRAAHDRAIRLRAAAFERALRGEGIPPPPLERFDELAARALPRRRDVEALREQSERLARRVARTLERGRDAARARRLEQRFPRWWRRDEDEAALRAR",
        "response#2": "MSPPSRPAPPPGSAPPDRLPAVPEPVPEPVPEPPPDPPDTRERLRRRVAAALVRTGAPLPPAAAADLATHAAQPQDARVTVRTAWSHPLPAVLVDDPPAPWPSLAGAVSPAPSPAPRPRRPWRRAVHVSLAYRFADRAALPAVRAELAAVLGTPPETLDAEIDRVAAAHRRTGLRPLADVLALDGPGPGDLLPADSSRPPGPRPRLLRLGPRRAAAPPPVDPALRRSALAAALHLHRLAALPLPPGAHRLLDRFGPDSADVWFAPPAAPRPGAVRIRLDTLHPAPPPARPAGPPPGTTALQAPDRLLLRTAPAPPPAPEPAPDRTDALITALRAAGFDVVTQPARRTPPR",
        "response#3": "MTPTTTPDHPPRHIPTPTTTPPTTPPTTPPPATTTPTTPPPSPTPPPRTPTPRTRTPRTRTPPPPPPPPRTPPPHPTPAHPTARLTTALTAAAHTITDTADRHRARAADDLARAAAELRTAATATAAAHRLAAHTHTTRAPDTHTAAARRRAALAAAARTLADHHRAAAATSTTATHTHLADTARTLATALREQPDPPPPPPPHPVPPALRAELHRLLTTPPHTPADRRPPTAPADWRPPTAPADRRPATAPADRRPATTRPPPPDPTAAALTALTRHTLDPATPAHHALAALADATGTALHHHTTHPHRPTTPTRPDRPTPPATTDTPHRPTTPDTPHRP"
    },
    {
        "reference": "MKSLVAHFSTPLITARLVPRCIIHRASISAVSFSTVRRRFSPLTMASAAQSSSQAVSYGSGNSDTDVFKLIQAHEEKAARLSPVEEIRTVLNGSICGMLSTFSQKYEGYPSGSMVDFACDADGSPILAVSSLAVHTKDLLANPKCSLLIARDPEDRTGLRITLHGDAVLVSEKDQAAVRSAYLAKHPKAFWVDFGDFSFMRIEPKVVRYVSGVATAFLGSGEFSKEEYQAAKVDPIAQYAKPVTSHMNKDHEEDTKAIVHNITSIPVESALMLDLDSLGFNVKATLQGNTFKLRVPFPRRAQDRKDVKTLIVEMLQAAKSN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Pyridox_Oxase_N that are essential for its biological function; 2. The protein should be classified within Split_barrel_FMN-bd sharing conserved structural features; 3. The protein must be able to perform the heme binding,cation binding,oxidoreductase activity,protein homodimerization activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0042803",
                "GO-Name": "protein homodimerization activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0042803",
                "GO-Name": " protein homodimerization activity "
            }
        ],
        "go_f_mapped": [
            12,
            183,
            4,
            37
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR012349",
                "InterPro-Name": "Split_barrel_FMN-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 64,
                "End": 218
            },
            {
                "InterPro-ID": "IPR011576",
                "InterPro-Name": "Pyridox_Oxase_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 85,
                "End": 210
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR012349",
                "InterPro-Name": "Split_barrel_FMN-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 64,
                "End": 218
            },
            {
                "InterPro-ID": "IPR019595",
                "InterPro-Name": "DUF2470",
                "InterPro-Type": "DOMAIN",
                "Beg": 241,
                "End": 314
            },
            {
                "InterPro-ID": "IPR011576",
                "InterPro-Name": "Pyridox_Oxase_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 85,
                "End": 210
            },
            {
                "InterPro-ID": "IPR037119",
                "InterPro-Name": "Haem_oxidase_HugZ-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 233,
                "End": 321
            }
        ],
        "ipr_mapped": [
            856,
            858
        ],
        "response#1": "PSLSSPPPSSSSPPSPPPPPPPSPTPPTSTTPPTTPTSTTTTPTPPPPPTTPTPTTSTTPTTPSTPTSTSTTTTPSTPTSSSTSSPTPSPTSSSTTPSSTPPSPPTPSSSSTSSPTSSSPSSTPTPPSTPSSSSTSSSTSTTTTSSPTSSTTTTRRRSPTRRRRRRRRRRRLRGGRRRRGDRDRRRRRSRRRRRRNRGGRRRRSRRRGRRRRGRRGGNGD",
        "response#2": "MFVNSNNFTKKNNNNYNSSSSSSSSSSSSSSNSSSSSSNSSSSSSSSSNSSSSSSSSSSSSNSSSNSSNSSSSSSSNSSSSSSSNSSSNSSNSNNNNNNNNNNNNNNNNNNNNNKTIKKNKTFILKKSNISNLNFNRFNNINKKNFFRIFFKKTNFFLFFFFNNNKFFKFFFNIKNKFFSRFFFNNKFNKKFFFFKKKNKFIQFKIKKNNKNINKNNKNKKNKKKRLKKLKLFFFNFNNFKLFNFFFKKKKKNFLKKNIKNFFFKNNFLNFFKNNFLFFKKKFNFNKKKKKNFFLNKKIKNKKKNKINKFFKKNNFFFNNFKNNNFKKNFFFLIFFKNNFKNFFFNFILN",
        "response#3": "MFNLFKNYLNNKNKIFFYNKNLNYNKYIYCKNYLKYFNFYLNFYYNYLNNIYINFIYIKNYFQYKFFKKKIFFYNKNKIFNCFINLFHFYFKNNIINFIKSNKFFFNYNFYIKFKKNLNFNKKKIFFYNKNFYIKKKNKKNLFLKKNIKKINNNNYYKNNNLKNNIIKKININNLFFFFKQNNFLIKNKIYFLNFNKYFIFNNFLKNKIFCKKKYYNFYFLKNLYFKFFFNKKNFFFFFFYNNLINFNNFFFYKNFNNIDININNIKINKLLNIKNNLYFINKKNKLKFFYNFKIFNIFYFLLLNYFNNIKLKIFL"
    },
    {
        "reference": "MSTTAHTEPSWADLPFLDFTDPNFSWDSPEVAEAREKSWIARTPLALLVLRYAEADQLARDKRLISGFRGLVDMVGTPEGPVRDFMVDFLQSLDGADHRRLRGLATHPFTPRRITAVQPFVRSTVEQLIDKLPQGDFDFVQHFPHPLPALVMCQLLGFPLEDYDTVGRLSIETNLGLALSNDQDILVKVEQGLGRMFDYLVAAIEKRKVEPGDDLTSDIVRAFHDGVLDDYELRTLVATVLVAGYETTNHQLALAMYDFAQHPDQWMKIKENPELAPQAVEEVLRWSPTLPVTATRVAAEDFEVNGVRIPTGTPVFMCAHVAHRDPRVFADADRFDITVKREAPSIAFGGGPHFCLGTALARLELTEAVAALATRLDPPQIAGEITWRHELGVAGPDALPLRFGAA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 406
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 43,
                "End": 403
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 194,
                "End": 371
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 243,
                "End": 260
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 355
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 278,
                "End": 289
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 366
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 348,
                "End": 357
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 406
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 43,
                "End": 403
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 198,
                "End": 220
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 324,
                "End": 339
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 355
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 366
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 93,
                "End": 104
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 278,
                "End": 289
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 296,
                "End": 323
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 138,
                "End": 154
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 155,
                "End": 170
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 194,
                "End": 371
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 243,
                "End": 260
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 355
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 278,
                "End": 289
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 366
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 348,
                "End": 357
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21
        ],
        "response#1": "MPEFVRRKTRPAIKEARAIIDRVFEERRAERERCKAEGKPYNDTIEWFEEVAKGREYDPVIAQLSLSVAAIHTTSDLLSQVMFDLCANPELIQPLREEIIRVIAEYGGWKKTALYNLKLMDSVLKESQRLKPVSLATMTRKATEDVKLSDGTFIPKGTKVMVDAYGMWDASKYPDAEKFDGYRFYRMRQTPGQENSAQLVSTSPEHLGFGHGKHACPGRFFAANEVKIALCHILLKYDWKLEEGAKPVLTGLGIFMNADPAAKLMVRRRKEEISLDT",
        "response#2": "MALDSPLLLVLALLLPFLLLLWSKPFNRTSNSSNLRKLPPGPWKLPVIGNLHQLGALPHRSLRNLAEKYGPIMHLQLGEVSTVVVSSPEMAKEVLKTHDLVFANRKIPEALDVSYHCSDIAFSPYGDYWRQMRKICTLELLSNKRVQSFQHIREEKVSDLVGYISKSSQGKPIDVGKAAFLTTLNLLSCSIFSRDLASYTEDSETGKEFKEVVWEVMELAGTPNASDYFPVLKGFDLQGIRRRLGIQFEKALKIVEDR",
        "response#3": "MLQVVARLSSRVFVGLPLCRNETWLKITVDYTVDAFVAAEELRLWPEALRPVVHWFLPSCRKLRAQLAEAREIINPVIEERRRMKAEAIASQKASVSKSSETKSSSAYSDTIQWFDENAKGREYDPAVAQLSLSLAAIHTTSDLLTQTLFDLCARPELIQPLREEIISVIRTEGWKKTALYNLKLMDSVLKESQRLKPVGLVGMMRKVVKDGVKLSDGTFLPKGTKVNVAAYAMWHDEANYPDAETFDGYRFVKMREVPGQENSAQLVSTSPDHLGFGHGKHACPGRFFAANEIKIALCHILLKYDFKLEEGKKPEAVNFGIKLLADPSAKIMVRRRKEEIDLSAL"
    },
    {
        "reference": "MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Beta-lactam/transpept-like, Beta-lactam/transpept-like sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity,organic acid binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043177",
                "GO-Name": "organic acid binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008800",
                "GO-Name": "beta-lactamase activity "
            },
            {
                "GO-ID": "GO:0008658",
                "GO-Name": " penicillin binding "
            }
        ],
        "go_f_mapped": [
            19,
            203
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 265
            },
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 259
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 265
            },
            {
                "InterPro-ID": "IPR012338",
                "InterPro-Name": "Beta-lactam/transpept-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 259
            },
            {
                "InterPro-ID": "IPR001460",
                "InterPro-Name": "PCN-bd_Tpept",
                "InterPro-Type": "DOMAIN",
                "Beg": 48,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002137",
                "InterPro-Name": "Beta-lactam_class-D_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 68,
                "End": 78
            },
            {
                "InterPro-ID": "IPR050515",
                "InterPro-Name": "Bact_Transpept/Beta-Lactamase",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 147
            }
        ],
        "ipr_mapped": [
            492
        ],
        "response#1": "AAAPAPPPPPPAPPPPAEPPPPPPPPPPPPPPPPPEPPPPPPPPPRRPPQEEAEERERERREAEAREREARRRAEEARERAEAAEEARRRAEEAEEARREAEAEERRRREEAEAAAARRRAEAEAAEAAREERDREEERREREEEEARAAEADEAAERAAEERRRREEEERAEEARDREEARQEAERRREAEEEAARRAEAEEARRAAAEAEAARRAEAEARRRREEEERRRAEEARRPPPAPPPPPPAAPPAPPLPPPPPPPAAPAAPPPPADAAAAAPAPEEEE",
        "response#2": "MNDIKNKEIEEDIEVDKDIKNEENIDDNIIEEEYIEINENIEKNDEYIKEKENLKEDKEIDNNLENEENMINNNEIKEKNIKKNKENINKKDENNNIKEDNENNEKIENVNNEYININENKNILSEEKIDENKEGNENNNIDIEKKDKKKEENIKDNIENEENINKEEDKKDENKEKINKNIKEKEKINENNEKIKEKEENIENKEEENKNINKNIEKEEEKEINENKDKIDKKIKENIKNKENINENIEEEIIGIDKENKNNNINNKEDIKENKIKIQKEKNEGIKIEEIIENNIEEINENINKNEDEKNNIININNDNNIVNKSINKKKKNKKKNNKNEDINIKEEIIINKEDKNIIIEN",
        "response#3": "MLVVLLVVVAPAAAVVADVDVVVAEVVEVVAAAEVDMVEDDVAVVEVEDVEAEEFEEVDAAADVDVAVEVVVAAAGEAAEPVEEAEDEADVVDVAEAEADEDEDEAEAEAAREADDEEDEDVDEAEDADDAAADEDADEGEEDEDEAEAEAEAEAEAEADEDEADADEDEEADADEAEEDEDEAEEAEAEEDEEDEDEDDDAAVEAAAAVEEDEVVAVVNAAEVVEDDVVAVVAEVVAVAAEVPEVAPADVADVAVADVADVEEDDDVEDVVDALVVVAGVEDADDD"
    },
    {
        "reference": "MMSRYEELRKELPAQPKVWLITGVAGFIGSNLLETLLKLDQKVVGLDNFATGHQRNLDEVRSLVSEKQWSNFKFIQGDIRNLDDCNNACAGVDYVLHQAALGSVPRSINDPITSNATNIDGFLNMLIAARDAKVQSFTYAASSSTYGDHPGLPKVEDTIGKPLSPYAVTKYVNELYADVFSRCYGFSTIGLRYFNVFGRRQDPNGAYAAVIPKWTSSMIQGDDVYINGDGETSRDFCYIENTVQANLLAATAGLDARNQVYNIAVGGRTSLNQLFFALRDGLAENGVSYHREPVYRDFREGDVRHSLADISKAAKLLGYAPKYDVSAGVALAMPWYIMFLK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Epimerase_deHydtase that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the nucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016853",
                "GO-Name": "isomerase activity "
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": " nucleotide binding "
            }
        ],
        "go_f_mapped": [
            61
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 337
            },
            {
                "InterPro-ID": "IPR001509",
                "InterPro-Name": "Epimerase_deHydtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 264
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 337
            },
            {
                "InterPro-ID": "IPR001509",
                "InterPro-Name": "Epimerase_deHydtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 264
            }
        ],
        "ipr_mapped": [
            208,
            7
        ],
        "response#1": "MKIEEITVDVEKKKLEEIKYRIEKELRKRNLEGILELSRKKIIIKDKDKRKAKEVRKILRKELYKGKKGVEEERIKPEEKIELEIVKKKSRELVIRVFSEDRKKIEEFLKILKEELKKRTEIKNLKIEDSERRGNKVSIILKRGIEENEMKKLKNLIEKELKKEVKVEIKENKLKIVTKSFKDFRRVKEIIREKELKFPLRILER",
        "response#2": "MTVVVTGGAGFIGSNIIKALNERGVTDILVVDNLTDGTKLVNLVDADITDYRDKTDFLADIKAGGDFGKVRAIFHEGACSDTTETDARYMMDNNYQYSRDVLHLCLDRSIPFLYASSAATYGGRTDNFVETREVDAPLNVYGYSKFLFDQYVRRILPDAKSQIGGFRYFNVYGPREGHGKVASVAFNFMTQFARGERPIIFGDGNFKRDFIYVGDVAKVNLWFLDNPEKFSGIFNLGTGQAQSFNDVAKAVIEVSGSSAEIEHLSDEEFKAKGLQSMYSDSYRATYDLTREHYYKTASTYAQEGENWLSKPEDTFGDTLNKRKIPEAEAKKA",
        "response#3": "MILVTGGTGFVGSEIVEELKKRGEEVKALKREDLKEEEKIKEFLEKEEVEAIIHNAALFNLKERENKEKMEKVNVEMTEKIAKSCLEKEIPIIFASSAAVYGETKEFKEEEKEEKPLNEYGKSKLKGEKILKKILKENSKGKISVLRYFNVYGPRQKREKTASVAENFLEKVKKGEKPKIINPEQKRDFIYVKDVAKANLDLLEKGEEGIYNIATGKAQKIEEVAEVFLKEQKKELEVEKKEEKREVPKEREEKYKKFLEEKEKD"
    },
    {
        "reference": "MKDLKVAVVGLGYVGLPLAVEFGKKRTVVGFDINQGRIAELRQGIDSTLEVDAAELKEASELSFTFNLQDLQKCNVFIVTVPTPIDEHKQPDLTPLVKASESIGKVLKKGDIVIYESTVYPGATEEDCVPVLEKFSGLRFNEDFFAGYSPERINPGDKEHRVSSIKKVTSGSTPEIAELVDSLYREIITAGTHKASSIKVAEAAKVIENTQRDLNIALINELAIIFNRMGIDTEAVLKAAGTKWNFMPFRPGLVGGHCIGVDPYYLTHKAQSIGYHPEIILAGRRLNDGMGAYVVSQLVKAMLKRRIHVDGARVLLMGLTFKENCPDLRNTKVVDIVRELAEYNIQVDVFDPWVSAEDAMHEYGITPVGTPSHGAYDGIILAVAHSEFKNMGAENIRKLGKAEHVLYDLKYLLDEDKSDLRL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf, 6-PGluconate_DH-like_C_sf sharing conserved structural features; 2. The protein must be able to perform the NAD binding,oxidoreductase activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding "
            },
            {
                "GO-ID": "GO:0016628",
                "GO-Name": " oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor "
            },
            {
                "GO-ID": "GO:0003979",
                "GO-Name": " UDP-glucose 6-dehydrogenase activity "
            }
        ],
        "go_f_mapped": [
            22,
            4,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 189
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 199,
                "End": 289
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014026",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_dimer",
                "InterPro-Type": "DOMAIN",
                "Beg": 200,
                "End": 288
            },
            {
                "InterPro-ID": "IPR028359",
                "InterPro-Name": "UDP_ManNAc/GlcNAc_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 422
            },
            {
                "InterPro-ID": "IPR028359",
                "InterPro-Name": "UDP_ManNAc/GlcNAc_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 416
            },
            {
                "InterPro-ID": "IPR014027",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 316,
                "End": 414
            },
            {
                "InterPro-ID": "IPR017476",
                "InterPro-Name": "UDP-Glc/GDP-Man",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 408
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 189
            },
            {
                "InterPro-ID": "IPR036220",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 298,
                "End": 415
            },
            {
                "InterPro-ID": "IPR014027",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 315,
                "End": 415
            },
            {
                "InterPro-ID": "IPR001732",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 178
            },
            {
                "InterPro-ID": "IPR017476",
                "InterPro-Name": "UDP-Glc/GDP-Man",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 420
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 199,
                "End": 289
            }
        ],
        "ipr_mapped": [
            503,
            7
        ],
        "response#1": "MASRLQDKVAIITGASSGIGEATARLFAKEGAKVCLAARREDRLKVVAAEIKALGGDVTVVPCDVAASSELTNEDFDKVIDVNLKGTFLMMREALKGMLAQGSGSIVNIASIMGLIGSTVSAHYTASKHGVIGLTKTAALEYASQGIRVNAVAPGYIDTPLTAETLTEEQKKAMLDAIPLKRMGTPEEVAKAVLFLASDESSYVTGEVLFVDGGYTAS",
        "response#2": "MTTALRGTTALVTGASSGIGAATARALADAGAELVLAGRRADRLAALAAELPRARAVPLDVTDDAQVAAAVAAVPRLDVVVNCAGYGLFAPVETTTDEELDRMFDVNVKGPVRLTRAALPALRATRGTVVNLGSVAGRRTYPGGSAYGATKAALHAFSEGLRQELAGTGVRVTSVSPGQVDTEFTAVARAHEGDAPYRPGDKLTADDVAAAVVYAVTQPPHVNVDDVVVRPTAQPWPR",
        "response#3": "MTTPPTTTPDLTGRTAVVTGATSGLGAATARALAARGARVVLAGRDPARLDAAAAAITTTTTTTTTTTTTTTTTTTTTTTTTTTTVRTAALDLADLASVRAFARTHAADGPVHVLVNNAGVMALPGRRTVDGFEAQLGTNHLGPFLLTRLLLPALLAAPDARVVTVSSTAHHTARLDLDDLDRRPYRPWAAYGRSKLADVLFTLELARRVPGRVTAVAVHPGTAATALTTDPAVERVLHRLLRPVLRRPEQAAAALVHAATAPELTGVTGRFLGPRGAAEPMGRPARPSRPSRAARDPDTARRLWDASERLTAPPEPPEPVPPAAAPPPTE"
    },
    {
        "reference": "MSAELASRGRKVYFVGLNEYPFLPLVAGLLRTYAEQDERIAAAYDFQEPVFLVAPVQEMADGIVEPDVLALSCYVWNFRRQMKVAKLVKERYPNVLVVAGGPHVPDRPGNFFEKHPYVDVLAHGEGEVAFRELLATRLSDHPDYTAVPGVSVRRGTEAVVGPKAKRLPRLIDTPSPYLLGVMDGAVATCRERGLRFYALWETNRGCPYSCSFCDWGSATMSTLRKFEDERLQDEIEWFARHDVEDLFICDANFGIMPRDLEIAHALAEARGELGAPRQVRVNFAKNSNDRVFDISKTWHDADLLMGTTLSMQSTDMDVLEAIDRKNIGLDNYRKLQQRYAAENIHTYTELILGLPMETARSFRDGIGSLLEAGNHEDLRVYELGILPNAPLNTPEKIEQYGLRTVPKRMYVERPGTPDDEAETFEMVMETNAMPRDAWVESFSFIQAVQFLHNGCYTRYLSIFLRQEHGIGYTRFYEGLQDYFTGRPDTVLGALYLRMRSLYHDYIDMPALPLANLVASQPDMAADLAPYGRRRGWTIDNWGWLRIATDFDRFHTELREYLATLGLDPAGDARLEDVLRFQQDVMLRPDYSPELGKSAEYAHDWPGYFAGGLLRPRRVRVAYGDQSFGANGRYRPVPGDLKAFTMAAIGTSYPVSRMGHFCHRFESAEVTSLAEPVVSEQW",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Elp3/MiaA/NifB-like_rSAM, rSAM that are essential for its biological function; 2. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding,methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0031419",
                "GO-Name": " cobalamin binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            79,
            183,
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 196,
                "End": 414
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 192,
                "End": 417
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006158",
                "InterPro-Name": "Cobalamin-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 65,
                "End": 134
            },
            {
                "InterPro-ID": "IPR006158",
                "InterPro-Name": "Cobalamin-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1,
                "End": 144
            },
            {
                "InterPro-ID": "IPR034514",
                "InterPro-Name": "ThnK-like",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 680
            },
            {
                "InterPro-ID": "IPR023404",
                "InterPro-Name": "rSAM_horseshoe",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 195,
                "End": 388
            },
            {
                "InterPro-ID": "IPR036724",
                "InterPro-Name": "Cobalamin-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 65,
                "End": 139
            },
            {
                "InterPro-ID": "IPR006638",
                "InterPro-Name": "Elp3/MiaA/NifB-like_rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 196,
                "End": 414
            },
            {
                "InterPro-ID": "IPR051198",
                "InterPro-Name": "Tetrapyrrole_Bchl_Biosynth_MTs",
                "InterPro-Type": "FAMILY",
                "Beg": 62,
                "End": 434
            },
            {
                "InterPro-ID": "IPR007197",
                "InterPro-Name": "rSAM",
                "InterPro-Type": "DOMAIN",
                "Beg": 192,
                "End": 417
            }
        ],
        "ipr_mapped": [
            195,
            196
        ],
        "response#1": "AGHGHRGGGHAQRGQQQHRGRRQHVPQHGPQRQRHHGQQHGRGGHHHRRDRQRQHGRQQGGGRRQHRGHQGHTRQHRRPQHGLGGQHHRHRRRQHRGCHGHGGGHGGQQQRGHQQRARDRQHPADQRGQAHPPRQRHLRRGQGHHDHGQRAAQPHGGPEGERRGRPYQAGHQDRGHQHQHDHRDRPEQQHQLRQQRHPHHGRGGGQQHHQRRGHRGQRGHDPQHQPGRQQQRRHDQQRDPYRHHGRHHGGGHDRQHQRDHDQRDGQHQQCVGRHGQHQQQQQHRDRHRQQHHQQQHHHRQQQQQRHDHQHRHRGHCRTRHHPG",
        "response#2": "RHRHHRRHRQRRQRHRRHGPRRGQRHRQRHQRHPQHQHQHQPQRRHHHPQHRHRHRQHRHRQHQHHHHHPHHQRHRQHHRRRQPPHRQPQRHRHHQHPHPQRPRQRQPHGHPPPPHPQRQPPPHRQPPRRHHRQRHPPQPPPNPRPQPHPHPQGHPQPHGRHQPQGHHQRQHQRHQPQQRRQQPRQQQHRRQQPRQHHRHRHQRQRRRQPPPQHPPRPQRQPPQHRHPHPQQHRHQPQPQPQPQQHQPPPQPQPPQQQRQPQPQPQPQPQRQPQPHHHHRHRHRHPQQRQPHPHHHPRHPHPQRQRQRQRQRQPQGHQRRHRHRHPQRQRRRQRQRRGPHHPHPPPGPP",
        "response#3": "MDGPQPPHHPRPPRPQPRRRRQQQEPPHPRRRRHHHRRQRHHRPPRHPPQHHHRQPPQQQQASPHHHHPRRRPHHQQQPPPQQRQQQQPPRQPRHRHHPQQPRPPRRQQQQQHPRRHLQQPPPHHPRRRQQQQPPHQRRPPPHHRQQHPPLHPRRHHPPPQQQPPPPQQQQQQPRPQRHHQHHRHHPHHHRRHQQHQQQPPRPPPQQQHHRRHRHHHHRPPPPRQQPHQQPRQHRHHHHRPPPHRRHRQHRRHRRRRRRRPPRRQQPQHHHHQRQHQPQHRRGRHAPPHRHRHLRAPP"
    },
    {
        "reference": "MSTPSKKRCGVLGATGAVGTRFILLLEQSPLLELVAVGASERSAGKKYRDAVRWKQASPMPASVADLTVRRCAPSEFSDCDIIFSGLDPVAAGDIEMAFLKANFAVFSNAKNYRLDPIVPLVVPLVNAGHIDVIPAQRKHYGLDKGLIVCNSNCAVVGLVIPAKALIQKFGPIESVSMVTMQAVSGAGYPGVSSMDIFDNIVPFIPGEEGKIATESRKILGNLNPDLAGFSDQQPLQVSVACNRVPVLDGHTVCASLRFVNRPAPTASQVRDALREYKSEVQLLGCPSAPRQAIHVLDDVDRPQPRLDRDTEAGYACSVGRIREDDSGVFDIQFVALSHNTVLGASGSSILNAESAILKGYI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Semialdehyde_DH_NAD-bd, Semialdehyde_DH_NAD-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,NAD binding,NADP binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": "NADP binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004073",
                "GO-Name": "aspartate-semialdehyde dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": " NAD binding "
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": " NADP binding "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            4,
            22,
            23
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 171
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 132
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR012280",
                "InterPro-Name": "Semialdhyde_DH_dimer_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 164,
                "End": 342
            },
            {
                "InterPro-ID": "IPR000319",
                "InterPro-Name": "Asp-semialdehyde_DH_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 238,
                "End": 252
            },
            {
                "InterPro-ID": "IPR051823",
                "InterPro-Name": "ASADH-related",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 362
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 171
            },
            {
                "InterPro-ID": "IPR005676",
                "InterPro-Name": "Asp_semi-ald_DH_pep-lack",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 356
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 132
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            }
        ],
        "ipr_mapped": [
            42,
            7
        ],
        "response#1": "MTTRIAVAGATGRTGAELVRLVLDHPDLELVAATASSRAGERLADLVPHLAGLDVPVGPVDEVLAEADVVFLATPPAVSAEYAARARAAGARVVDLSPAYRLDGPVYVPGAEEAVRARCIAGRRRRRGRDGRRVGARAVRRAGRPAVCRHHRPGGPRRRALELRAGRRRGVRRPRPRERRAGPGLPGVDRPGHRRRAGRRRA",
        "response#2": "MTTVAVVGARGRIGTELVRLVDGHPELRLGALVARSGAGRPLAEVAPHLAALTGVPVHADPDLDAVAAAADVVFLALPAGVAVDAAPRLRAAGTRVVDLSAAARFGPYYVRGLEERVRDEPDVNLVSCGGQATIPLVAAVSRVLPVDRAVIDVVAALESTGPAVDGNIADLRAGTANIVPTSPGAARAAGEVLGRPVRGVLHAVPVPFNVQTDTLTVTADPDADVDADADADADVDADVDADVDVDVDVDVDVDVDVDADVDVDVDVDVDVDADADVDVDAGVDVDAGVDVDVDADVDVDVDADTTTARDPLPDDFAAVALVARFVGQTSSSHHPRK",
        "response#3": "MKVAIVGARGIVGAELVRLIEADPDLELVAVTSRSRAGEPLATVVPHLAHLTDITVQETDVDAVAAAADVAFLAAPAHIAADAAPRIRAAGCKVIDLTSAARAPYYVPVVGLEQHLADLTDQDIVNVVSCTANCMAIPVAAVSRVAPVEYGEIVASIAVSTTRRGPGTAANVAELTESTTTAIEKVGGAVRGKAIINLVPADHPIMRDTLHIRTAEPDRAAITAAVRDAVAATPGVRLVDEPQIGTDATDSTFHTVYLEVEGAGDYLPSYAGNLDIMTATALATARRIAATTTPTTESTR"
    },
    {
        "reference": "MSWPLIGAYALLAFVAIIALNVTYQFLFRLLNKTRPPLVFHWIPFIGSTIHYGMDPYGFFFSCREKYGDIFTFILLGRPTTVYLGTQGNEFILNGKLKDVNAEEVYSPLTTPVFGSDVVYDCPNSKLIEQKKFIKFGLSQTALEAHVPLIEKEVEDYLAMSPNFHGTSGEVDITAAMAEITIFTAGSALQGEEVRSKLTTEFAVLYHDLDKGFTPINFMLPWAPLPHNKKRDAAHARMRAIYIDIINKRRNAGDNVPEKLDMIGNLMQCTYKNGQPLPDKEIAHIMITLLMAGQHSSSSISSWIMLRLASQPAVVEELYQEQLANLERTGPNNSLAPLQYKDFDNLPLHQNVIRETLRLNSSIHSLMRKVKNPLPVPGTPYVIPTSHVLLSAPGVTALSDEYFPNAMAWDPHRWETQAPKENDKDDIVDYGYGAISKGTSSPYLPFGAGRHRCIGEKFAYLNLAVIVATMVRHLRFSNLDGQTGVPATDYSSLFSGPMKPARIRWERRAAKSG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 39,
                "End": 488
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 351,
                "End": 362
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 444,
                "End": 453
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 453,
                "End": 464
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 53
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 58,
                "End": 81
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 381,
                "End": 395
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 453,
                "End": 471
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 283,
                "End": 309
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 362
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 397,
                "End": 415
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 437,
                "End": 453
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 446,
                "End": 455
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 512
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 508
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 39,
                "End": 488
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 351,
                "End": 362
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 444,
                "End": 453
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 453,
                "End": 464
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 53
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 58,
                "End": 81
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 381,
                "End": 395
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 453,
                "End": 471
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 283,
                "End": 309
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 362
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 397,
                "End": 415
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 437,
                "End": 453
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 446,
                "End": 455
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 512
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 508
            },
            {
                "InterPro-ID": "IPR050529",
                "InterPro-Name": "CYP450_sterol_14alpha_dmase",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 501
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "PYENNPYSLAHRQLVLSAAAIHTTSDLLSQVIYDLCARPELVQPLREEIIGVIKEHGWKKSALYNLKLMDSVLKESQRLKPVGQVGMRRFVVKDGVKLSDGTFLPKGTRICVSAYAMHRDPAIYPDPDNFDGYRFYRMREAGQENSAQFVSTSPEHMGFGLGKHACPGRFFAANEVKIALCHILLKYDFKFPEGTERPKLIGAGFTVSADPSAKIMVRRREEEIDLGLA",
        "response#2": "MAAAAIHTTSDLLTHALFDLLARPEYIQPIREEQISVLTSTQGKWNKTALYNMKLMDSFMKESQRLKPVVIVGMQRIVTEDIKLSDGTVLPKGTKISVSAHVMWDAEVYEDPEKFDGYRFVRNEKSAQFVSTSPNHLGFGHGKHACPGRFFAANELKIALCHILLKYDFKLEDGKRPKNTNAGMFIMADVSAKVMVKRRKEEIDLSAS",
        "response#3": "MLSEETSHVLRTQWTDNKEWHSVSLKETMLRMVAQLSSRVFLGEELCRNEKWLNITINYTVDAFTAAEELRGWPEFLRPVVHWFMPSCKKLRAQLAEAREIINPVLEARKREQAADPDAKKYNDTIQWFEDVAKGSNYDPAVAQLSLSVAAIHTTSDLLTQVLFDLCARPELIQPLREEIIRVLNSHGWKKTALYNLKLMDSVLKESQRVKPVNVVGMMRKVVKDGVKLSDGTFLPKGTKVSVSAHKMWDARIYEDPEKFDGYRFVKMREDPGQENSAQFVSTSPDHMGFGLGKHACPGRFFAANEVKIALCHILLKYDIKLEEGTKPKSVHSGIFLLADPSARILVRRRKEEISLD"
    },
    {
        "reference": "MHYLDNLLLNTDSYKASHWLQYPPGTDASFFYVESRGGVYDQTAFFGLQSILKEAINRPVTHADIDDAKALLAAHGEPFNEAGWRDIVDRLGGQLPIRIRAVPEGCVVPTHNVLMTIESTDAKAFWVPSYLETLLLRVWYPVTVATVSWQVKQIVRDFLQRTSDDPEGQLPFKLHDFGARGVSSLGSAALGGAAHLVNFLGTDTLSALLLARAHYHTPVAGYSIPAAEHSTITSWGREREVDAYRNMLTQFARPGAIVAVVSDSYDIYRAIREHWGTTLREEIIASGATVVIRPDSGDPVDVVEQCLLLLDEAFGHQVNGKGYKVLNHVRVIQGDGINPQSLRAILERITAAGYAADNVAFGMGGALLQKVDRDTQKFALKCSAVRVDGAWIDVYKDPITDQGKQSKRGRLTLLRDRATGQYRSALLDEVATHAGDSDDALVTVWENGQMLREWTLEQVRAHADAARL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more N/Namide_PRibTrfase that are essential for its biological function; 2. The protein should be classified within Aldolase_TIM, Nicotinate_pribotase-like_C sharing conserved structural features; 3. The protein must be able to perform the pentosyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016763",
                "GO-Name": "pentosyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0047280",
                "GO-Name": "nicotinamide phosphoribosyltransferase activity "
            }
        ],
        "go_f_mapped": [
            84
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR041525",
                "InterPro-Name": "N/Namide_PRibTrfase",
                "InterPro-Type": "DOMAIN",
                "Beg": 172,
                "End": 417
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 137,
                "End": 399
            },
            {
                "InterPro-ID": "IPR036068",
                "InterPro-Name": "Nicotinate_pribotase-like_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 171,
                "End": 464
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR041529",
                "InterPro-Name": "DUF5598",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 99
            },
            {
                "InterPro-ID": "IPR016471",
                "InterPro-Name": "Nicotinamide_PRibTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 409
            },
            {
                "InterPro-ID": "IPR041525",
                "InterPro-Name": "N/Namide_PRibTrfase",
                "InterPro-Type": "DOMAIN",
                "Beg": 172,
                "End": 417
            },
            {
                "InterPro-ID": "IPR016471",
                "InterPro-Name": "Nicotinamide_PRibTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 465
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 137,
                "End": 399
            },
            {
                "InterPro-ID": "IPR036068",
                "InterPro-Name": "Nicotinate_pribotase-like_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 171,
                "End": 464
            },
            {
                "InterPro-ID": "IPR016471",
                "InterPro-Name": "Nicotinamide_PRibTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 468
            }
        ],
        "ipr_mapped": [
            883,
            101,
            879
        ],
        "response#1": "MRTELPADGTDVPAPAGLGAPAARERADGDRRGRGAGRPAAGESRAAVPGQGPDGAGPGGDGVAAAGRAVPGDQRAAAGGPVAGPPGAVRVPDRRGVPADAAVPVAAGARRLPAVVPVLAARDRRCHGPRRGRGRTAPGALRPDPDPAGPDRPGPGAPGGADRADPDEAGRDDPADPALPDRADPDRAALAGPDRADHRAPDHLPHRPRPPALPLPPPRPQAPPGGPPRPAVPPPPRPWPPPLPRQARLRRLRRAGRPAGRARRRRRPAAAD",
        "response#2": "MPAPAARPAGDPAGPARHPAHPRPQPGPRRRPRRRPHRPGHQAAPVVLAAGPAAVDAAGPGPGRLHRRPAQHHAGAAHPAGGRPGPAPRPVSARRPAAVLGVGAGHRVAPAVHAAHHAGGAGPRPAAGAASHRAAGRLLRGRCGGAGRAGQGRPAAAQRAGRARAGGQPPGHQPVPRAGRVPGPRHQARPQGPAAGRRGPGAVRLPR",
        "response#3": "MAVRAAWAPTAATAAASTSSASSGPRRARPAAASSGAARAAAGRPREGPAGAGRRTAAGATGAARAAGCGRPVRSPGRPHSARPSRSGGQDRPGPARRPEDPRGSTRRSPAPRPAPRRPRPPHRQPDPDRTGPGAPGPRPRAGRPAPRRGPAPGRTTPSTGPGRPDGGPRTGCRDRRAGAAPSAPAAVRRIPAPPPPTPSRTRWPARWPD"
    },
    {
        "reference": "MGRVTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAARTFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNMPDPIPVIILARLAVDLSFHGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIHHGFKSSQTQQRTLFLRLPQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016747",
                "GO-Name": "acyltransferase activity, transferring groups other than amino-acyl groups "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 147
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 146
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 147
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MPPRRMTTTPPPGRRPEAGLAAVAAVPGRAVVTVAAPGPAAVLAAALGRPPGAVEELRYWRDGATLRAVLPDGRTVEVAVAPPPPTVRGRRILRAEPLAALLGRVALAHGVPVRLETPPPPPPPLDEVEAHVAGLVRRLTARPPGTVVEPVVEPPPPAAPLPDPAALARWADRFLARVRADLARGALGPARPPTWPPPLPAEVREGLRDVAEAARALEPPGPADPEGPSP",
        "response#2": "MPPPPPEDPREELARLAEEVEAFEAELAEAEARLEALRERLREAEARLAEAPAEETRGLREAYEGELEALGEELAAALEAYEDALRERARELLAETPPEPSEEALREKVAELEARLAALSERVRAELPALRREVDELEARLAEARERLRRAEAELARLREERRRLEAALDEARARDAAAEARRREVREALARAAEALREARRRLEELRARWRELGAA",
        "response#3": "MADETDDEEPAPADEDEAAAAAAAEDEAAARAAAEAEAERARREREERERAEAERAAREAEAEAEQRRREAEQRAREAEQARREREQAQREREQAEREAARERERARAEAEAAEREARRREEEREQRERREREERRRREREARERERKREAAERERERERRERERAERERARERELAEREEAQRAAEQARERAEHERREAEQAQREAERAQREAEEARAQAEAERERARAARAAAAPPPPPPPLPPPPPPPPPPPPPPPPPPPPPPPPPPVPPPPPLPPPPPPPPPPPPPPPVPPPPPPPPPMPPLL"
    },
    {
        "reference": "MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTTKTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISKGLGRYDVPVFRLGRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLLSFKTLYAALSASGRL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016747",
                "GO-Name": "acyltransferase activity, transferring groups other than amino-acyl groups "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 152
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 152
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 69,
                "End": 147
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MRTHTHTTHRNTRPAAHPTARRTAHRAAPTAHPAAPRTAPRTAPRPRTPPAAPRTRTVRSGTRPAGPTARPAARRTAHTTAPRPPARAARTAPRPPAGAARTRTPPRPGPRRPTAPRPPADTRPTARTAPDPAPPAPRRRRRTRHTRTRTRRTPTRAGPAGRRIRRATPRTRTAATRTRTTTPRPPAAAADTTAADTRTTAADTTRPGGDAPRTPAAAADTAAAAPTTAGTPADTRRPATRTAPRPPARRTPPTPTRRTRRPHGARPAPAAAAPGRAGR",
        "response#2": "MTPPRPPARPAPGPRTDPARDRARDRARDRARDRARDRDRIRDRDRDRSPDRDRSRSRDRSRDRSRDRDPRPDADRRPRADAPPRRTAAPRPRAPRPPRPAAEPPRTVADALPALTVLSTDPVTNRPLLRIVVDDGPATEPRPAPSRPAAPRPAAPRPAGRRPTAPRPAAPRAAAPRPAAPRPAPDRPPTADRPEPPPAADRPDRPRRTDRPGRPPRTDRPDRPPTADRPEPAPRADRPAAAPPRTAAPPRLAPARAAVVTLTRLPLPEPARRELAAHGAALAAAAARGWTVTALDLGPRLPGPAAGTVRVADRTAALTAAGRVLTAAEHPARAETPRRRRSAAAARPPAAPRPARPHRRRTGAAAPRPGAAPRPDRADARRTPGPDRTDGPDRPATPHR",
        "response#3": "MTATPPAPARPAPDPDRTPARRRWARLVRRTAARGLTGPVLVDADTGRVADLGPWTPDNGLRAALAALPPDPEPEPGPDPVRRAAVRLTLEALPDLRPAERLTPAERTALRTALAAAGADRLAALRTDGRTLARTADRLYPAPPPGRRVRSARPESEPAEPEPAEPEHAESEPGPAESEPAESGSAESGSAESEPAESEPAEPEHAESEPGPAESEPAESGSAEPEPAEPAEPEPEPADPAADLTRLADLAAQVHLARLRHAPHPALPDRLATAERRLRAAAADLTAAVTPAAAALALAPDPAAADRVLADLAAPATARPDPRPRATRRVPLRRRPPARPDRPTPAPPTPTSPTPASPDPAPPEKESR"
    },
    {
        "reference": "MATPSKKRCGVLGATGAVGTRFILLLSQHPLLELVAVGASDRSSGKKYRDAVRWKQSAPMPAKVADLTVRCCDPAEFSDCDIIFSGLDPDAAGEIEMAFLKANFAVFSNAKNYRLDPMVPLVVPLVNAGHIDVIPAQRKHFGLDKGMLVCNSNCAVVGLVVPAKALIQKFGPIESVSMVTMQAVSGAGYPGVSSMDIFDNIVPYIPGEEGKISSEARKILGDLNSDLAGFSDQKPLQISVACNRVPVLDGHTVCASLRFVNRPPPTASQVREALREYKPEVQTLGCPSAPKMSIHVMDEVDRPQPRLDRETEGGYACTVGRIREDDSDVFDIQFVALSHNTVLGASGSSILNAESAILKGFV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Semialdehyde_DH_NAD-bd, Semialdehyde_DH_NAD-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,NAD binding,NADP binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": "NADP binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004073",
                "GO-Name": "aspartate-semialdehyde dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": " NAD binding "
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": " NADP binding "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            4,
            22,
            23
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 182
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 132
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 182
            },
            {
                "InterPro-ID": "IPR000319",
                "InterPro-Name": "Asp-semialdehyde_DH_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 238,
                "End": 252
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 132
            },
            {
                "InterPro-ID": "IPR005676",
                "InterPro-Name": "Asp_semi-ald_DH_pep-lack",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 356
            },
            {
                "InterPro-ID": "IPR051823",
                "InterPro-Name": "ASADH-related",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 361
            },
            {
                "InterPro-ID": "IPR012280",
                "InterPro-Name": "Semialdhyde_DH_dimer_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 164,
                "End": 342
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 134
            }
        ],
        "ipr_mapped": [
            42,
            7
        ],
        "response#1": "MVPDGVVPDGVVPPPPPPPPPAPPPPAPPPPPPPAPPAPPPPPPPAPPAPPPAPPAPPPAPPAPPAPPAPTTVVGVGPVGAAVVARLGRAGRPRVRVVADRPAAAATVPEVPVDGPTAPATPAAVGRPAGPARTVVVGTPDPDRVRACPRLPVPAADRPVVVDATVAPAPLGGGLPPGVTVVDGVDAAGVDRLVARLTDRTATDRTTDRTATDRTATDRTTPDRTAPDRTATAPDRTAPNRAAPDHVALVGAGPAAAAAARRLAAAGVDRLTVVDPRPDRLPPLVAAALAPTGGDVPVRVTTDPAPLAGAAVVVLAGPDDAATVVAAAAADGVVVVDVATRDRTGRAVRLVAGPADPAAVAGVARTVVDAPTDRTDPDRPPTPDRTDPDR",
        "response#2": "MLKVAIVGATGRVGTELVKLVENHPDLELKLLVASRNAGENVSTLTNLKTNLVVETFDEEKAKDIDVAFFATGAKVAKEAAPKFNAAGVKVIDLSSAFRIPYYVPVVNLEAEKKNIDQNIISNASCTTNCLVPMVAAISKVAKVEYGEIVASIASKSAGPGPRGNIDEFTELTAGAIENINLAEDKVRGIDIDTKDKEITWEKKFEVVEDLTGADVGRADKEFVELHTIGGLEDPTSAIDERVEDAGLKMKEGSASKVIAEISSPLNYVIPRRNRLRYFPK",
        "response#3": "MIKVAIVGASGRVGTELVKLVEAHPELELAALVSRSSAGKKVSEVVPHLKGKTDLVVKSAEEVDFSEFDVAFFATAPGAHKEFAPKAVAAGVKQIIDLSAAARFGEPVVVPEVAEKYRNGMHVQPEIGALEFPAGGSPRHRCRFVISGAAWITHQPRPKVTDSPHTPPMCVVGGSLSRKSAPSPSSRSSLSISSFEHADHVYVGDH"
    },
    {
        "reference": "MRIRPSPPKKPTPGLLHEYADRLVAFEYSASKGLKPHTLLFISGLGDGLGTVAYLEDIVAALEGSQWSVFSPVISSSYGGWGTSGLGRDTDEMARCIEYIQKYKEGSGVHETERKIVIMGHSTGSQDVLTYISSPNPRHPQPGLDPGHGHRHKRMPPLRPQVDGAIMQAPVSDRQAIQTVLEEGNERHSAKYMRKVVNDAIAYAKKHTYEDYDSLDTIIPLPITAAIGYPASTAVSSRRFLSLTSPDSPDSPGEDDLFSSDLTDERLRKTFGMVRHRGVLKDQKGLLVLYSGNDPSVPAFVDKEGLLRRWRWATDADEKRAYWHGESGIIPGATHTLEGPGQVEQRKELVRRVWMFLADVEGDPRTSCHSARPLS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 361
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 356
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 361
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 356
            },
            {
                "InterPro-ID": "IPR013744",
                "InterPro-Name": "SidJ",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 362
            },
            {
                "InterPro-ID": "IPR013744",
                "InterPro-Name": "SidJ",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 357
            }
        ],
        "ipr_mapped": [
            35
        ],
        "response#1": "MAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPPPPPPPPPPFRERWVEVEPGVRLWVRELGNPAGTPVVVLHGGPGASSDSFARYTVRPLAERFRLILYDQRGCGRSPLPPWPPEALTVEDHVADLEKLRRALGLERLVLLGHSWGGMLALWYALRYPERVAALVLVSTTAGRPEEGASYYEDLRRRLERALSPEERAAYEAALAGGGTPEEAEAALRRAAERAWRAAGRAAAPPTEEGRRALEAALEYLRRAYLEEWRRQPPPPSPPPPPPPWNYHNRVVWPALRGFDLVGRLGEVRVPTLVVHGTRDWVTPVEDGRRTAELIPGARFVEIEGAGHMPWLDEPEAFARAVEGFLEEVEEG",
        "response#2": "MPPPPPPAVPPPLPEPPPPPPPPPRPRPGPPWSPPPPPPRPPPPSSPRPPPPPRPRRARRRVRRAGRGAVRALLAAALALALAACAAPRPAPPRPAPPPRPREGWVEVNGVRLFYQVYGPERGPAVVLLHGYSDTAITWRRVAPLLAREGYRVVVPDLRGHGRSEKPGPYTIEAYAEDLAALLDALGIERAVVVGHSMGGFVALELALRHPERVRALVLVDTRPPRGVPQPPEQRRELARLVRERGVEAFARELVPRLLVERPELVEEVVRRIRRTDPEGAAAAHEALAEVDLTERLGEVRVPTLVLVGTRDLIPPEEARRMAELIPGARLVTLEGAGHAVHLERPEEFAREVLAFLRSLE",
        "response#3": "MRTVVLVHGAGLDRSSWELVRPHLEARGYRVLAPPLPLRPEATIEAMAEAVWRLVPEGPVAVVGHSMGGAVALHLALRRPERVAKLVLIGTSARLRVNPRLLEMARREPRRALEEVLRYSYAPGFLEEHPELVEENRRRFEAVAPEVLVGDFEACDTFDVMDRLGEVRVPTLVVVGERGRMTPPRFARLLAEKIPGARLEVVEGAGHMVQVERPEEVARLIEEFLA"
    },
    {
        "reference": "MTDTTLVEAGDPAEDAPEWPMKRDTGCPFDPPPGVRKLLAEKPLSRARIWDGSTPWVVTRHADQRALLSDPRVSHDGLRDGYPHISADFKFLSMAQPSFAGQDDPEHGRIRRMVTLPFTARRIEAMRPAIQKITDELIDGMLAGPKPVDLVEALALPVPVRVICEMLGVPYEDREFLQQNNNAMIYRDTAQGDAQKAAIAQAMYLKELVGTKLGDRGDDILSDLAVQVEAGEITQDDAAGIGMMLLGAGHETTANMIALGTLALLENPEQLAEVRDSDDPKVIVNTVEELLRYLTIAQDTVRRIAAEDIEIGGVVIKAGEGIVFPLNAANWDPDLYPEAPDRLDIHRANARRHLAFGYGVHQCLGATLARVELQIVYSTLLRRIPTLALAGTLDEIPFKHDQIAHGVYELPVTW",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 231,
                "End": 383
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 414
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 356,
                "End": 365
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 285,
                "End": 296
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 248,
                "End": 265
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 414
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 231,
                "End": 383
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 414
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 356,
                "End": 365
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 285,
                "End": 296
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 248,
                "End": 265
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 102,
                "End": 113
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 363
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 166,
                "End": 181
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 285,
                "End": 296
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 149,
                "End": 165
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 303,
                "End": 330
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 203,
                "End": 225
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 414
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21
        ],
        "response#1": "MSVAAIHTTSDLLTQTMFDLCARPELIQPLREEIISVVKEDGGWKKSALYKMKLMDSVLKESQRLKPIQMVSMYRKAMEDVTLSDGTFIPKGTQIAVAAHRMWDPALYEDSEKFDGYRFVRMREVPGKEENAAQLVATSPEHLAFGHGRHACPGRFFAANEVKVALCHILLKYDWKFPEGSPRPKNSYGFFNMSADMGAKVLVKRREVE",
        "response#2": "MDSIKAVILDMFVAGTDTSSSTLEWAMTELLKNPRVMKKAQEEVDSVVGKERLVEESDIISLPYLQAVVKETLRLHPPAPLLLPRETSEDVKVSGYVIPKGTKVLVNVWAIGRDPSCWEDAMEFKPERFLDSKVDVKGRNFELIPFGAGRRICPGLPLALATVELALAQLLYHFDWKLPNGLKPEDLDMEEKSGLTVQKKEPLVAVPVPRLKP",
        "response#3": "MSRRITAATPATGGRGRRRRKGRGRRGRRRRHHHHHHHHHRHHHHPRPRRHLLLPARPLRPRRRPPLPLPPLRPPPLAPPHRRRPLRPPPPPPVPPARRAPPRRRGPPPPPPPPPPSSSSSSSSRASSSSSPSSSSSSSSTAASSTASSSTASSSSSTSSSSSTSSTSSSTTTRPRPPPPRPCHPRRRCGSLAAARRRRR"
    },
    {
        "reference": "MNHIPVNRGVCLMGRSQNSEFETASDEPIAVIGLSCRLPKASGPQELWQLLDDGASAVTRVPADRETPPSTEEESADGEAAGARWGGFLDRVDTFDAGFFGISPREAAAMDPQQRLVLELSWEALEGAGLVPATLRDTGLGVFVGAARDDYATLYRRREGRAVDHHAMTGLHRSLIANRISYALGAHGPSMVVDTGQSSSLVAVHLACESLRRGESDIALAGGVNLNIAAESARETAAFGGLSPDGQCFTFDARANGFVRGEGGGLVVLKTLRRALADGDLVHGVILASAVNNDGPSDTLTTPSRRAQESLLTRVYRRAGVTPTEVGYVELHGTGTKVGDPIEAAALGAVLGTGRDTPLPVGSIKTNIGHLEGAAGIAGLIKALLQLRRRRLVPSLNFSTPNPDIPLDALNLRVQQESAPWATPSGGGRTLVAGVSSFGMGGTNCHVVVSAAPVPEDGETTSEAGATGPDSGPALLPWVVSARSPQALRDQAGRLAAWADSPAGREASPVDIGWSLATSRTHFEYRAVVSGSDRDELVASLRALASGSPVTAAGAVDGGGRLGLVFSGQGSQRAGMGRELYVAFPVFAEAFDEVCGVLDEVMGALPPSEGWAGSLREVMFEVSSDLLDETGFTQPALFAFEVALYRLLESWGVAGEVVAGHSVGEIAAVHVAGVLSLADACALVAARGRLMQGLPSGGAMVAVEASEEEVTALLAGREGEVGIGAVNGPRSVVVSGGVAVVEEVAAHFAGLGRRARRLKVSHAFHSPLMDPMLEDFGRVVAGLSFAVPELTVVSGLTGAVVSADELCSVGYWVRHAREAVRFADAVGAMAGVGVGRFVEVGPGGVLSALVRECLAEGGAGSVVAAVRGNRAEPVALLSAVGELFADGYPVDWTAYFAGWPAARVELPTYAFQRSRHWLENVPELAVSTTPPAVPREPVTPDSDHPDPVETVRQLTAHVLGLTAAADVEMTRSFKDLGFDSLMSVELRDRLCAATGLSLATTLLYDHPSPAETAEFVRARLTGDEAAAVEVVAARAVEDEPIAVVAMSCRFPGGVRTPEDLWELVRDRVDAVSVFPSDRGWNADAGLFPPAGGFLYDGHHFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPVSLRGSRTGVFVGATAQDYTPKLGEPADGLEGHLLTGGTVSVASGRISYFLGLEGPAVTVDTACSSSLVSLHLACRSLRQGETTLALAGGVTLMATPGMFAEFSRQGGLAADGRCKAFAEAADGTGWAEGVGLVLLERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLAPADVDLMEAHGTGTRLGDPIEAQALLATYGQGRSGDRPLWLGSVKSNIGHTQAAAGVAGLIKTVMAMRHGTMPATLHVDRPSSHVDWSTGAVELLTEAQPWPDTERPRRAAVSSFGVSGTNAHVILEQATEPAALDAAPDAIVSDAVVAWPLSARDVGALREQAVRLVARVTGDPYVRPADVGHSLAATRSSFEHRAVVVGRERAELLAGLEALASGETAANLATGRASADGAGKVVFVFPGQGSQWPGMGLELAAHSPVFAAVLEDCGRALAAYVDWDGHTLHEVLAQEDGAPSLERVDVVQPALWAVMVALAALWRSHGVQPDAVVGHSQGEIAAACVAGALTLDEAAQVVSLRSRAITALAGAGQMVSVPLPEADTAEWIRPWADAGQIGIAAVNGPGSTVVSGDSAAMDELMEALAAQDVRARRIPVDYASHSPQVARIRDELLHALDGLTPRPATVPVFSTVTGEWLDDTTPMDAEYWYRNLRQTVRFEEAVRALADSGCGVFIEASPHPVLTIGVQETLDVLDRTGVVTGSLRRQKGGPDRFLSSLAQVHTHGGRVDWDTVFAGTGATRTDLPTYPFQRHRYWLERPQAPAVAPAASPAASVSETDSTRYRVVFKPLPEPTAARLSGTWLLVVPDTDEPDARVDAVTGALVTAGATVERIVVEAGADRADLAELLAALATDVGGVRGVVSLLALSEDADAMRPSVPSGLASTLTLVQALGDADVSAPLWCLTRGAVSVGASDRLDSPVQALVWGLGRAAAVEHPERWGGLLDLPATLTGRVLDRLVGVLAADGDEDQVAVRAAGVFGRRLVRGNSAPTRIDHSWQAGGTVLVTGGTGALGARVARWLVDSGAEHVVVASRQGADAPGADRLRDELTGLGARVTPVACDVSDRSAVAELVDRCAEQGDPIRAVVHTAGVGVTKPLADTTPDDLAVSFDAKVAGATHLADALGADLDAFVLFSSAAGVWGSGGQGAYGAANAYLDALAAQRAADGLAATAVAWGPWDGGGMSADAAVIDMDALRRSGLTAMDPDRAIDALDRALTDGETALTVVDVDWTRFAEVFTTARRSPLLADLPEAARLVGPAPTARENSSPVAARLAKASSAAEGRRVLLDLVRGRVADVLGHATPDTIRADRPFKDLGFNSLMTLELRSGLNEATGLRLSATTLFDHPTPSALAEHLAGELLGTPRAEAGPEMPATAPEVTEDPIAIVAMSCRFPGGVGSPEALWRLVADRRDVISGMPADRGWDIDGIYDPVPGVPGRTYTRQGGFLDGVGEFDAEFFGISPREATAMDPQQRLLLETSWEAFERAGIDPTQLRGDSVGVFVGCTGQDYVPRLHETSDELGGYALTGAAGSVASGRVAYTFGLEGPAVTVDTGCSASLVALHLAVQSLSRGECSLALAGGVTVMSNPGTFIEFSRQRGLAADGRCKAFSDSADGTGWAEGVGMLLVERLSDARRNGHEVLAVVRGSAINQDGASNGLTAPNGRSQQRVIRQALASASLTPAEVDVVEAHGTGTKLGDPIEAQALLATYGQDRPAERPLLLGALKSNIGHTQAAAGVAGVIKMVLAMRHGVAPQTLHVEQPTAEVDWSAGAVELLTEARPWPDADRPRRAGVSAFGVGGTNAHVIIEEAQSAPAQERTAPEPPAALPWLVSGATPDALRAQAERLLTHLADQPETHAADVAYSLSLTRSSLDHRAAVVAADRDELLAGLAALAEGRSAPGLVRGAPHSGDRVAFVFPGQGSQWPGMAQELAAAFPAFAARLRACEDALAEFVDWSLTDVLSEAPDAPPLDRVDVVQPVLWAVMVSLAELWRSYGVEPDAVLGHSQGEIAAACVAGALTLQDAARVVALRSKAIVAIAGQGGMLSVPLSREGLRPHLARWQDRLSVAAVNGPETVVLSGDVQAVDGLCAELQGEQIRAKKIQVDYASHSAHVEAIEAELFDALAPITPRAGSVPFFSTVTGDWYDTTGLDAGYWYRNLRQTVELHRATEALVEQGFGVFVESSPHPVLAVGMQDTVEAAGGDAVILGSLRRDDGGPDRFLRSLAEAHTHAVGVDWHALFTDGAGHRVELPTYAFQRKRYWLQDTAPEHRADAPAVDPVDAAFWEAVEREDLDALAGVLDLGTPDDTASLDTVLPALPVLSSWRRKRLDRSTVDAWRYRVEWRRIDDAPAPATLTGTWLVVIPEGYEADERVTASARALAERGADVVEVRVDEAGEDRTALAERLSDTGADTGPVAGVLSFLALAEQGFPQHPEVPTGLALTLHLVQALGDAGIDAPLWSVTSGAVSTGDDEAPSHPVQAHIWGMGRVAALEHSERWGGLVDLPEAPDEQAARRLGAVLADTRGEDQVAIRPSGLYGRRLARAAATEAGERQRWTPRGTVLITGGTGALGAHVARRLAAQGAEHLVLVSRSGEAAPGADDLRTKLGVPVTVAACDIADRDQVAALLARLEADGTPVRTVVHTAGVARLTPLAQTDLAELADVLSGKAAGARHLLELLDLDNLDTFVLFSSIAAAWGVADHGAYAAANAYLDAMALQYRAQGLPVSSVGWGPWDGDGMVSLNKLLARRGIPVIAPDLAITALQQALDERDTYVAVADVDWDRFTQVFTSARPSPLLADFTETAADDRETASATAHGTDSELVRRLNALPEDERAQALQDLVLTEAAAVLGHTTTDALGAVRPYRDLGFDSLTSVEFRNRLRDATGLALPATLVFDHPTPQATTEYLLQRIAGDKPIVDRASSSAVAAVEADDPIAIVAMGCRYPGGVASPEELWELMAAEGDAISGFPTDRGWDLDALYDPDPDRAGHTYVREGGFLHDAAEFDAEFFGISPREASAMDPQQRLLLETSWEAFERAGIDPAALRGSATGVFVGSNYQDYGLGSGSGSQQSSGVSEGHELIGSAPSVLSGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQSLRQGESDLALAGGVAYMANPRAFVGFSRQRGLARDARCKAFADRADGMTLAEGVGLVLLERLSDARRLGHPVLAVVRGSAINQDGASNGLTAPNGPAQQRVIRQALANARLTPSEVDVVEAHGTGTALGDPIEAQALLATYGQERVEGQPLWLGSVKSNIGHTQAAAGVASVIKTVLAMGRGTVPATLHVDRPSSHVDWSAGAVELLTEARAWPENGHPRRAGVSSFGISGTNAHVILEQAPAESGEPPQQDLPVDGESAASVVPWVVSARSVRALQAQAGQLAAWAASPAGEQASPADVAQALATTRTFFEYRTVVVGGDRAELVETLRSLSTDPSAAGTVRRADTDGGGRLGLVFSGQGSQRAGMGRELYVAFPVFAEAFDEVCGVLDEVMGALPPSEGWAGSLREVMFDVAGGSLDETGFTQPALFAFEVALYRLLESWGVAGEVVAGHSVGEIAAVHVAGVLSLADACALVAARGRLMQGLPSGGAMVAVEASEEEVTALLAGREGEVGIGAVNGPRSVVVSGGVAVVEEVAAHFAGLGRRARRLKVSHAFHSPLMDPMLEDFGRVVAGLSFAVPELTVVSGLTGAVVSADELCSVGYWVRHAREAVRFADAVGAMAGVGVGRFVEVGPGGVLSALVRECLAEGGAGSVVAAVRGNRAEPVALVSAVGELFADGYPVDWTAYFAGWPAARVELPTYAFQRSRYWLEELAGTAVRRTEAGGQDEVDAAFWEAVEQGDLSSLGTGEGVDGEARLADVLPVLSSWRRQAGQVSLADSWRYRVTWNALPEPGVASFGGTWLLLAPAGSEAAGSLVRSLAEAMAEHGAEVVTVDLGHPDSDRARDALAEQITGRLDGLAPGQVGGVVSLLALAEGTDPHHPTVSRGLALTLSAVQALGDAGVTAPLWCLTRGAVSAGATSGPDEPVQAQVWGLGRVAALEHPDRWGGLLDLPEQVDSRTVRRLVRALAAGHRPGGEDQIALRTAGVLARRLVQDAAPAGDSVAWTPSGTVLVTGGTGAVGGHVARWLAARGAERVVLVSRRGPEAPGAQALHDELTEAGVRVRLVACDLRDQEAVTALVAGLADEGDLTAVVHAAGVLDDGVLASLSVERCAEVLAAKAQAAHHLDLATREVDLDAFVLFSSASGVLGSAGQANYAAANAYLDALAELRHALGLPAVSLAWGRWADGGMADQDVVAGRLDRDGWPAMAAEAALNAMARAVTAGRPAVMVADVDWQRFAPAFTAARPSPLLSALPQAQLPTAAAHGPAEGEQSSWASRLAELPAAEQQTALLDLIRGQVASVLGHASVQTIDPARAFKEIGFDSLTAVELRNRLNAATGLALPTTLVFDYPTPEALAEYVGSEVLGTSSSAAVGGPLVVAAVDEPVAIIGMSCRFPGGVQSPEELWDLVAGGRDTISSFPADRGWDIDTLFDPDGERSGTSSTRYGAFLDGAADFDPAFFDIGPREATAMDPQQRLLLETAWEAFERAGIDPAALRGSATGVFTGTNGQDYATLASGAAAEFEGYLGIGNAGSVISGRLAYTFGLEGPAMTVDTACSASLVALHLAAQALRQGECSLALAGGATVMATPGAFVEFSRQRGLAPDGRCKAFSASADGTGWGEGAGMLLLERLSDAERNGHPILAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALANARLSASEVDVVEAHGTGTKLGDPIEAQALLATYGQDRAEDRPLWLGSVKSNLGHTQAAAGVAGIIKSVMAMRHGTLPATLHVDEPTPEVNWSTGAVELLTESRPWPATDHVRRAAVSSFGVSGTNAHVILEQAADPVAEAESGAALVPDAVPVPWVVSARSADAVREQARRLHTHLMTGREWRPADVGYSLATARSRFEHRAVVLGEDQGELLEALEALAEGRGDSRVRVGAGLAGGRTGFVFAGQGSQRLGMGGRLREMFPVFGEAWDEVVAELDGRLGRPLGEVVFAEEGSEQASLVDRTEFTQPALFAFEVALFRLLESWGVVPDVVAGHSIGELAAAYVAGVLSLSDACALVVARGRLMQALPAGGAMVAVQVTEAEARRLVEGEPSGAVDIAAVNGPESVVIAGDEDVVLRVQEIVRGRGRKTKRLTVSHAFHSPRMEPMLDEFRRVAETVTYHEPRIAVVSAVSGEVAGAELRSAEYWTRHVREAVRFYDAVRCLRSEGVSTFVEVGPDGALSALGQDCLVGEEARGTEFVSTVRAGRDEAESVVAAVGAAHVRGVPVDWAAYYAPYGPRRADLPTYAFEHQRYWLDTSARPGRDATGLGLGSAEHPLLGAAVALADGDGVLLTGRLSLATHPWLADHQVQGAVLFPGTAFVELALRAGEQVGADCVEELTLEVPLVLPERGGVQVQVVVGAADEQGGRPVTVHSRPETGVDEPWTRHATGVLASGAATVPAETGELAVWPPQGATAVDIDGLYDRLVDGGFGYGPVFQGLRAVWRRGSEVFAEVALDDTHRDGAGEFGLHPALLDAALHAIGFGEFVSDGGAGVLPFSWNGVHLYASGADALRVRVSGVGVGANEVALVVADGSGRPVAAVESLVLRPVSADTIAAGAGARQSLFRVGWRQVAVPDQAGAGEWVALDRGAGWAQGEGCEVLPDLAALGSAVSAGRSVPRLVVAHFAADREVPVTAGVRGVTAEGLELIQSWLADERFADSRLVIMTRQAVAVDAGEGVFDLGAAALWGLVRTAQSEQPGRVVLVDVDDLDAVSRVVGIGDEPQLAVRDGRVFVPRLMRAEAIDGVPVWDPEGTLLITGASGALGGVVARHVVREWGVRHLVLASRRGAEAPGMTELVAELGELGASAAPVACDVADRDALAAVLAGIPAVHRLAGVVHAAGVLDDGVVGSLTPERLETVLAPKADAAWHLHELAAELDLSVFVLFSSAASVFGGAGQGNYAAANAFLDALAARRRADGLVATSLSWGLWDQAGGMTGQLGEADVARMSRSGVLPISVGEALPLLDAGVTGGDAWLAPVRLDLAALRQQAIATGGVPALLRDLVRVPNRRKAETGGSSTGGSRSTLLDKLAGLTDAEREQELLDFVCEHTAAVLGHSGAGMVDPGRGFLEAGVDSLAAVELRNRIGGVLGIRLSATLVFDYPSPVLLAGHIGEQLALDEPAPEPMMAAELERLEAAVTAGRFDDASRDEVAVRLRKLLTYFDTVADTARGETDDGDVASASVDELFALLDEELDDR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, Thiolase-like, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, NAD(P)-bd_dom_sf, Thiolase-like, Thiolase-like, ACP-like_sf, ACP-like_sf, ACP-like_sf, NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, Thiolase-like, Thiolase-like, Thiolase-like, Thiolase-like, Thiolase-like, Thiolase-like, NAD(P)-bd_dom_sf, ACP-like_sf, Thiolase-like, ACP-like_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site, Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,lyase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": " lyase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            32,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 945,
                "End": 1020
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5277,
                "End": 5519
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3708,
                "End": 3956
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5561,
                "End": 5636
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5050,
                "End": 5266
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1036,
                "End": 1402
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3969,
                "End": 4066
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 937,
                "End": 1023
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5542,
                "End": 5640
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7305,
                "End": 7402
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2422,
                "End": 2521
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6847,
                "End": 7025
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 7355,
                "End": 7370
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2442,
                "End": 2517
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 449
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2537,
                "End": 2962
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2441,
                "End": 2554
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3986,
                "End": 4100
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 945,
                "End": 1054
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3486,
                "End": 3698
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 5591,
                "End": 5606
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1936,
                "End": 2144
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3993,
                "End": 4059
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2447,
                "End": 2513
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 949,
                "End": 1016
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5566,
                "End": 5632
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7330,
                "End": 7396
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4082,
                "End": 4453
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1030,
                "End": 1475
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5650,
                "End": 6099
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 468
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2532,
                "End": 2981
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4076,
                "End": 4538
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2472,
                "End": 2487
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7037,
                "End": 7243
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7321,
                "End": 7404
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5564,
                "End": 5636
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3991,
                "End": 4063
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2445,
                "End": 2517
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 948,
                "End": 1020
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 7328,
                "End": 7400
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7325,
                "End": 7400
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3988,
                "End": 4063
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5654,
                "End": 6029
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5558,
                "End": 5671
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2156,
                "End": 2398
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 975,
                "End": 990
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4084,
                "End": 4514
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 4252,
                "End": 4268
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 945,
                "End": 1020
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4630,
                "End": 4921
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 565,
                "End": 856
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 6190,
                "End": 6511
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3070,
                "End": 3385
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1563,
                "End": 1886
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5277,
                "End": 5519
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3194,
                "End": 3259
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3708,
                "End": 3956
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5561,
                "End": 5636
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1038,
                "End": 1454
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 5655,
                "End": 6081
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5050,
                "End": 5266
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 6561,
                "End": 6726
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1036,
                "End": 1402
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3067,
                "End": 3355
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3969,
                "End": 4066
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 937,
                "End": 1023
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5542,
                "End": 5640
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7305,
                "End": 7402
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2422,
                "End": 2521
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4627,
                "End": 4923
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6847,
                "End": 7025
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 7355,
                "End": 7370
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2442,
                "End": 2517
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 697,
                "End": 761
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 449
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2537,
                "End": 2962
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1561,
                "End": 1852
            },
            {
                "InterPro-ID": "IPR041618",
                "InterPro-Name": "PKS_DE",
                "InterPro-Type": "DOMAIN",
                "Beg": 5003,
                "End": 5044
            },
            {
                "InterPro-ID": "IPR041618",
                "InterPro-Name": "PKS_DE",
                "InterPro-Type": "DOMAIN",
                "Beg": 3434,
                "End": 3484
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 3712,
                "End": 3887
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 7038,
                "End": 7216
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 5281,
                "End": 5459
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 2160,
                "End": 2337
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2441,
                "End": 2554
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 26,
                "End": 451
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3986,
                "End": 4100
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 401,
                "End": 503
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 1407,
                "End": 1526
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 2917,
                "End": 3034
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 6034,
                "End": 6153
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 4467,
                "End": 4592
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 6561,
                "End": 6841
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 2539,
                "End": 2789
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 5656,
                "End": 5906
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 275
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1039,
                "End": 1279
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 4085,
                "End": 4339
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 945,
                "End": 1054
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3486,
                "End": 3698
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 5591,
                "End": 5606
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 5819,
                "End": 5835
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1936,
                "End": 2144
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 6689,
                "End": 6838
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4762,
                "End": 4826
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3993,
                "End": 4059
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2447,
                "End": 2513
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 949,
                "End": 1016
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5566,
                "End": 5632
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7330,
                "End": 7396
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 283,
                "End": 398
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 5914,
                "End": 6031
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 4347,
                "End": 4464
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2797,
                "End": 2915
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1287,
                "End": 1404
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4082,
                "End": 4453
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 1192,
                "End": 1208
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 562,
                "End": 858
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1030,
                "End": 1475
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5650,
                "End": 6099
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 468
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2532,
                "End": 2981
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4076,
                "End": 4538
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2472,
                "End": 2487
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 6191,
                "End": 6493
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4630,
                "End": 4935
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3071,
                "End": 3368
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 565,
                "End": 870
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1565,
                "End": 1868
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1563,
                "End": 1871
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3069,
                "End": 3371
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6189,
                "End": 6496
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 563,
                "End": 873
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4628,
                "End": 4938
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2538,
                "End": 2964
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7037,
                "End": 7243
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 6561,
                "End": 6661
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6318,
                "End": 6383
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7321,
                "End": 7404
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5564,
                "End": 5636
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3991,
                "End": 4063
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2445,
                "End": 2517
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 948,
                "End": 1020
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 7328,
                "End": 7400
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7325,
                "End": 7400
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3988,
                "End": 4063
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5654,
                "End": 6029
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4087,
                "End": 4517
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 5658,
                "End": 6084
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1041,
                "End": 1457
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2541,
                "End": 2967
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 29,
                "End": 454
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6189,
                "End": 6482
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5558,
                "End": 5671
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 2702,
                "End": 2718
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6550,
                "End": 6844
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 936,
                "End": 1018
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1692,
                "End": 1758
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2156,
                "End": 2398
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 975,
                "End": 990
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "SENLKNFEKNSKNFENFENSKDLKNFENSENLEDSKNSENFSENLKNSENFDFENFENLKNFKNLEKFENLKNFENFKNLENFENFEFSEDSKNSSEFKNSKNSSENFENFEDFKNFENFSENLKNFEDSKDFENFENSENSENFDSKNFKNFENYSEKNSEKNTEDLENFENFENFENFSENFEFKNSENFENFSENFEDSKSFEDSNFSDQSFENFEDLENFSDSSDFSKNSENFENFENSENSENSENFSKNLENFENFKNFKNSENDSENSENLKNFENFENFEKNFKDFKNFENSKDFENFEDFKNFENFKNFDFENFEDFKDFKNLKNFDFENFENFSDFSENSSEFSEDSEN",
        "response#2": "MKKIKFINNNNFFFLWKNNIFLNINKNNIFNINNFKLFNFNLKKIKNNNIFIINIFNFIFFIIFKNFIINKNFYNFFYIKKKNKFNILNFMFNFIINKKKIIFQIKKINNLIFKKLFFFFFNNIFKKIINLNNKIKFIKKINYFFIYKKIFNFIFNNNFIIFIFFKIFLIKKNIKFIKKIYLKKFIIFNFIKKKIKLNKHIKKKKKF",
        "response#3": "MKINDFNKEILFLKKINFNINNFSKIKKLIDKNFLNKKIFIINNKNFKIKNYKKIFNFFKKNINNIKIKKIFKNNLKIFIFFKNFIFYNIYNIINLIKNFFCNSFKKNNFNIFKNLNFNKIIFKIKFNYFFIKNFFLIYKIFKIFEIFNINIKIKNKKFFKNFNNFKKSIFFYNNFKKNYFKIKNFIFKNKILNKIFINLSIKNINNLIFLKIIQIFIISKINNIKNKNNNKFTNNFKIKNIFNIFFFFLNNNQKILIKNKKYLKII"
    },
    {
        "reference": "MAGYLPEPLRMMVTNPAISDFTSDGPLPYALRQKFTGWPPPPAAADISLASQTVLVTGATSGVGLEAARQLAQLGPRLLILGARNLSKADGVKRQLEQDTPHVAVQVAKLDLEDLSSVDRFVDGLHASAIHLDLALLNAGFFANDDRMTPDGYSSLFQVNFLSTAYLAFRLLPLLQTTTTAPEASPQGPRLVLVTSEAHAWTTFPVPPEPAENSLPILSSFRQKESLGSADDQYYRAKLLLALIGKELSRRLTTMQMATSVVITTPGFCASNFFPDSVMTRLIQLISARSIQQGGALHVFAATAQGPQMHGAYLRDGKPTGLSKFAEGPQGQILQQRLWVEMEQFLAGRGYLLSSILKPSSPLQIDGPV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 48,
                "End": 321
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 176
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 48,
                "End": 321
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 176
            }
        ],
        "ipr_mapped": [
            9,
            7
        ],
        "response#1": "MAKVALVTGSSRGIGKAIAVKLAKEGVSVVVNYNSSEAAAKEVVEQINKEGSGKALAVKADVSKSSDVKSLVDTTVSTFGGLDIAVNNAGVELRAPLEETTEEDFDRTMAINLKGTMLCMKHELPHLFKTKGNIINTASVLGFVGSTGMTVYTAAKHGVVGATKAAAVEYASKGIRVNAVAPGVVETDMHKSVPEEMKQEVIDSTPLKRVAKPEEVA",
        "response#2": "MGRLEGKVALVTGASRGIGRAIAFALAEEGARVVVNYHRSEEAAREVVEEIRRRGGEAVAVRADVSREEEVRRLVEAAVEAFGRLDIAVNNAGVGIVKPVEEMSVEEWDRVLAINLRGVFLCTKHELRVMLPQGRGSIVNLASIAGLVGSPLMAPYVASKHGVVGLTKALALEYAARGIRVNAVAPGWVRTEMTEKVRRVAEPEEVARAVVFLASDEASYVTGVVIPVDGGLTA",
        "response#3": "MTAPLPNTTSQSIRTYMSTESTSGPSSTPPAAAAAAAGKGRLKDKVAIITGAASGIGAASARLFAAEGAAVVLADVREAEGRALEREITAAGGRAVFVRTDVSREDDVERLVAAAVATFGRLDVAFNNAGIGGRPFAPTADTSLEEWQRVIDVNLTGVFLCMKHELRQMLKQGHGSIINTSSISGVIGSKMVAAYTASKHGVVGLTKSVAVLYAKMVAAYTASKHGVVGLTKSVAVLYAKQGIRCNAICPGGIETPMTYARAATDEEKEAVAAMRERFIGATALRRMGEPEEIAYAALYLASDEASYVTGQSLVVDGGMTAAG"
    },
    {
        "reference": "MLNDYLQWEKFILRGVEFPTRYRVDGDEVEITPSSRLYVSGMGGSGVVGDLIRDFSIVWNWDVEVTVVKDYFLRARDGLLIAVSYSGNTVETLYSVEYAKKRRIPTVAITTGGKLAQMGVPTIIIPKASAPRAALPQMLTAALHVVRKVYGIPIEIPEALEPPNDPLIHKLMEDFQKRPTIVAPETMRGVAYRVKNEFNENAKIEPSVEILPEAHHNWIEGSERPIVALTSPHIPREHQERVKATLEILGGTLYVVEMSTRGVLTFLREVGVASIKLAESRGVNPLATPRIEALKRRLQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more SIS_dom that are essential for its biological function; 2. The protein should be classified within SIS_dom_sf sharing conserved structural features; 3. The protein must be able to perform the carbohydrate derivative binding,glucose-6-phosphate isomerase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0097367",
                "GO-Name": "carbohydrate derivative binding"
            },
            {
                "GO-ID": "GO:0004347",
                "GO-Name": "glucose-6-phosphate isomerase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0097367",
                "GO-Name": "carbohydrate derivative binding "
            },
            {
                "GO-ID": "GO:0004347",
                "GO-Name": " glucose-6-phosphate isomerase activity "
            },
            {
                "GO-ID": "GO:0004476",
                "GO-Name": " mannose-6-phosphate isomerase activity "
            }
        ],
        "go_f_mapped": [
            168,
            170
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR046348",
                "InterPro-Name": "SIS_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 24,
                "End": 296
            },
            {
                "InterPro-ID": "IPR001347",
                "InterPro-Name": "SIS_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 177
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR019490",
                "InterPro-Name": "Glu6P/Mann6P_isomerase_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 177,
                "End": 298
            },
            {
                "InterPro-ID": "IPR019490",
                "InterPro-Name": "Glu6P/Mann6P_isomerase_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 177,
                "End": 285
            },
            {
                "InterPro-ID": "IPR046348",
                "InterPro-Name": "SIS_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 24,
                "End": 296
            },
            {
                "InterPro-ID": "IPR001347",
                "InterPro-Name": "SIS_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 177
            }
        ],
        "ipr_mapped": [
            434,
            435
        ],
        "response#1": "MTDDRPDWADPATRARTADAVDALVDRHGRPVTAADVRAAADPDADSPDPAADAPAAADAAARGALAAAVAAADGGPDPDADPPDPDGRPAGDPVHPADLARRAADLHAAADAADAAAAPRDRGPRYRPPALTDPVARRVRAAAGDDPARPAGVADPRPDRRDPDGDRPRRDRRPPPPRRRPPDRRRVRPPNRPRRPRRPRPPRRRPTGTPPRPRRRPPPRPGRHRRPPGLRRR",
        "response#2": "MGDDGADRDERDERPDRRERLAERPDVGDDPPTDPDEPDRADRAAAVRRDARDVVETVADAHPDRPDPDRDAGDRAAGRAATAADRSRPERRRTRRYGETVALLAVARYERRRPDDPVRDRVDAVADGVDRLADGDRDRVAERLAGDDPPDGEEARRAADRLRDAVPDRLATGDSDDDPDGDPDRPAETERRRELRAVDRIVDAVLDETDPDAVREDARDAGLDADDATRDRLRDRLAAAGVDPAVPYDPDDDDGTTDETVRDRVRAALDADPDGDPAPRRAVAVEDARGRRTDADDAERAADALRRLGARDRAARAALEWDDGPPPPGDPDERRDDDDR",
        "response#3": "PPLPPPPPPPPPPPPPPPPPPPRLPPDPPLAHLALLAALEALERGLPPPPREALEALSLPPPPPAEARALARALLEALRALLEAEALARALEEEAGLPLPLEEVPALEAAAALLEAEGPEALARALARALPPPGRGGPEALARALEALEEATRALPPPPEALEALARALEALEALEALREALEEALEEVRRALEAEGVREVLEEALRALAEAEEALRALLEALGLPPPPPPVPPPPSPPPPPLEALEEALARALALLRVLGLEAPPPPPLPPPALPPPPALEELRRRLAALEPALEALRRERLAALLEALEALEARGLPPEAEALAALLLPPPGEGEAEALRAALRALEEALRERGAPEAEREALREALEALARAFGLPPPPPRP"
    },
    {
        "reference": "MSVKKAGVLGATGSVGQRFILLLSKHPEFEIHALGASSRSAGKKYKDAASWKQTETLPETEQDIVVQECKPEGNFLECDVVFSGLDADVAGDIEKSFVEAGLAVVSNAKNYRREKDVPLVVPIVNPEHIDVVENKVKQAVSKGGKKPGFIICISNCSTAGLVAPLKPLVEKFGPIDALTTTTLQAISGAGFSPGVSGMDILDNIVPYISGEEDKLEWETKKILGGVNAEGTEFVPIPESEMKVSAQCNRVPVIDGHTECISLRFANRPAPSVEDVKQCLREYECAASKLGCHSAPKQTIHVLDQPDRPQPRLDRDRDSGYGVSVGRIREDSLLDFKMVVLSHNTIIGAAGAGILIAEILKAKNII",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Semialdehyde_DH_NAD-bd, Semialdehyde_DH_NAD-bd that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,NAD binding,NADP binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": "NADP binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004073",
                "GO-Name": "aspartate-semialdehyde dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0051287",
                "GO-Name": " NAD binding "
            },
            {
                "GO-ID": "GO:0050661",
                "GO-Name": " NADP binding "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            4,
            22,
            23
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 132
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 174
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 130
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 132
            },
            {
                "InterPro-ID": "IPR051823",
                "InterPro-Name": "ASADH-related",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 365
            },
            {
                "InterPro-ID": "IPR000319",
                "InterPro-Name": "Asp-semialdehyde_DH_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 243,
                "End": 257
            },
            {
                "InterPro-ID": "IPR005676",
                "InterPro-Name": "Asp_semi-ald_DH_pep-lack",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 360
            },
            {
                "InterPro-ID": "IPR012280",
                "InterPro-Name": "Semialdhyde_DH_dimer_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 165,
                "End": 345
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 174
            },
            {
                "InterPro-ID": "IPR000534",
                "InterPro-Name": "Semialdehyde_DH_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 130
            }
        ],
        "ipr_mapped": [
            42,
            7
        ],
        "response#1": "MTAPGPPRVAVLGAAGRTGAELVRLLDGHPRLRLVAAASRSRAGRPLAEVVPHLAGTGVPVTDDFDAVLAEADVVFSATPAAVAAEAAPRVRAAGARLVDLSAAYRTAPYVPVVVPEVLDPRRPWRPPRPSPAAGPPGRLPGAPALRAPPRRRRRPPRRPGPGPPPGRRRRRRAPARAPAVRRAPAVERAPAVRRPPAVRRPPARPRPADRAAPRPSARPAPAPRAARPARGPGTVRRRRPGRRRSPPRGRSAPPRRRPPARRRSPPRR",
        "response#2": "MDVAIVGATGAIGTRLAELVAERDDLELAALTARAGSETAGRPLGEVHPDLAALDVPVTDADRDRVAAAADAVFFATSADVAADDAARLRDAGARVLDLSGAFRTDCYVPIVDGRAAVAEYDGDVVVNPNCTTNALVPLAAVAADHVSVEYADIVSTVAASATQRTIDEVDDPVRVRSARESVVPSSGGATRMIGGLLGDDAERLRGTAFRVPTANVQRDTLYVATAADVDREAVRDAVRTTAERTAALGYDTPGVDPPPEPPERPARGRTVETA",
        "response#3": "MIKVGVVGARGRIGTELVRLVDAHPDLELVFASSRSTAGRRLSEVAPHLRHLRTDVEVVDAPDADAVDVVFDATGAFVAADAAARYRAAGRTVVDLSSAARAPGVPFVVGVENLADDVAADDNIVSVASCTANCLVPLVAAVDRVAPVERAVMSAVQAVTSAGPTTRANIAEFTENTRAVLSGRRDLAPQLLGENAFAGAIGASTNYVPSYDLEVPEKLKAVLPDLADKLTFTSVRVPVFNGSIVDVTLRLARPATADEVRAAVERAAADAPGVQLVDEEPVSTLDVNGTRGSSVLRAGTTVLNDHFVRVVSWYDNEFGYANRALDLALHVARTTTTTR"
    },
    {
        "reference": "MASSALTPVAIVGYACKLPGDVSSPDDLWELCSRGRTGWGPTPSTRYSKDAYYHPAPGKHGCINTEGGYFLKEDPARFDAPFFNMTIQEATALDPQQRLLLECTFEAFENSGMTKEGIAGKDIGVFVGGSFADYEVNNTRDIDTAPTYQATGCAPAMQSNRLSYYFDLRGPSMTVDTACSSSLVALHSAMQSLRNGESSSAVVAAAHLNLTPDFFVTMSNTQLLNDAGKTFAFDHRAISGFARGEGAGSMILKPLDAAIRDGDVIRAVIHNSGVNQDGKTNGITVPNGRAQSDLIKQVYSKAGLDPAECGFSECHGTGTKVGDPIEVAGIHEALGAGRSPRNPLFIGSVKSNVGHLEGASGIVSVIKAAMMLEKGMVLPNANFETANPNIPLEQYNMKVPTSTRPWPRGKKYVSVSNYGFGGANAHVVLGAAPKGLKTTMTTIRSLEDAPEEPLCKLFVLSAHDSQALQKEITDLGVFLEQRPEVFEKLLAGNVAYTLGERRSHLPCRLAIAAVSSDELGQSLATTKVPTFRARNEPTLGFVFTGQGAQWATMGAELARDYPIFAAALDTADDTLKALGADFSLKEEMLKPADISLINAAHISQPACTALQIALTMLLSSWGIHPAAVVGHSSGEIGCAFAAGIIGLEDAMKIAYYRGQCMLSLKKKAVGKPQGTMMAVGTSAENVRPLLDAVSKGYITVACINSPASVTLSGDVEAVEELQPILTEKSIFNRQLKVGVAYHSAHLEPVVDEYLDLIKNIQPASTATATFYSSLLGRVAEASELTPEYWVQNLTSPVRFSGGLSAMARETGSKTIDHLVELGPHSALQGPIRDTLATIDAAKGKMHYVSVLARGQNASECALRMAGALYMKGLSLTFGEINFPRTKSVNQKLITDLPRYPFNHETRYWHESRLAQKHCFKEGGRNDLLGSLADWSNDLEPTWRNIVKLDDLPFLRSHKMQDMPVFPMAGYMGMALEAAARRAIARGVQFDRFEIREFVVSSALVFNEDTDVEMTITLKPYSEGLRGAASDLWDDYKICSWDAKRGWLQHCHGLVGVRNSPAANAVDAHRIQSASKAFEACKASIISASTETVDVQAMYNTLTTIGAGYGPVFTGLEPCQASDTTAHAQLVVPDTKSLMPKGYETELIVHPALLDQIIQIVWPIFGAGRQGLDTLYMPTFVKNFSISRNFASMLGNGLEVFGAGAPNNEAPEPTKFGFFVVGSSDASEPLVQFDGLTMTPLRESSGSSGPQARELCYKIDWQTVSDEDIGLEKSSSDASDTPIKADSLVSTPFTRDEAVCVVYNKATEKDLAAEVADNVWKTSGVQAELVTLSKVIPADKRVIFVSTGNNVLSGIDATMFGTLRQMLLSARKVLWIYKEGPDVDDVDGSMVVGFTRAIRSETSANIVTLGLQQATGKTLVENIFTVLTKTSADSPSTFKDDKEFILKGDDLLVPKVVDDEELNVRLHQESQDSVIYQQPFAQSDRRLKMVIATLGSLDSFYFVDDEPKPLNDNEVEIEVKATGMNFKDVVVSMGQLNQPYIGVECAGVIAAVGKKVTDVKVGQSVMAMTEGAYSTYARCLSTSVAPLPEKMDFTAASTIPVVFCTAYYGLFDLGRLTEGESVLIHAAAGGVGQAAIMLAQTCGAEIFATVGSLDKKQHIVKEYGIPEDHIFYSRDTAFGPAIRQVTGGKGVDVVLNSLGGDFLRESWDCLAPFGRFIEIGKADITKNSRLEMAQFEYNVSFASVDLTKVAAYKPKLMKRLLNDVEKLMSSGSIRPVGPITSYGINDVEAAFRSLQSGKSMGKLVIAPQSGDSVQAIAPKKTATLFKEDASYLIVGGTGGLGCSIARWMASRGAKHICLSSRRANITPRLEALITDLSILGTKVSVRACDVADAGSVETLVKDLKKESPIRGVIQGAMVLKDVLYEQMTLDDFSAVVNPKVAGTLNLHNSLGTSELDFFIALSSVAGVVGNRGQAAYAAANVFLDTFMAHRKAQGLPGTSLDLTAVSDVGYLADNSERAADVLRNLGGETIEESEILGLLTAAVTGKITASNNHVITGLKINPGSEPFWCHDAKFSNLLAAAASQSSAEGGNANIPLPQALKSAANGEKALEVLYGALVTKLAAVLMLSVEEMEPSAAVASYSLDSLAAIEVRNWIAREADANVQVLELLTSPSLMELAKLISKKSKLVSFE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, NAD(P)-bd_dom_sf, Thiolase-like, ACP-like_sf, Thiolase-like, ACP-like_sf sharing conserved structural features; 3. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,oxidoreductase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            4,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1827,
                "End": 2041
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1590,
                "End": 1750
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 429
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2110,
                "End": 2181
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2107,
                "End": 2184
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2113,
                "End": 2184
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 454
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2111,
                "End": 2185
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2114,
                "End": 2188
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1488,
                "End": 1623
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 541,
                "End": 857
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 9,
                "End": 434
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 1828,
                "End": 2005
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1084,
                "End": 1243
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1827,
                "End": 2041
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 542,
                "End": 855
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 925,
                "End": 1115
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 2183
            },
            {
                "InterPro-ID": "IPR032821",
                "InterPro-Name": "PKS_assoc",
                "InterPro-Type": "DOMAIN",
                "Beg": 387,
                "End": 480
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 431
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1590,
                "End": 1750
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 429
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2110,
                "End": 2181
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 925,
                "End": 1246
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2107,
                "End": 2184
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2113,
                "End": 2184
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 267,
                "End": 384
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 921,
                "End": 1246
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 454
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 540,
                "End": 839
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 673,
                "End": 737
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 1511,
                "End": 1582
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 1494,
                "End": 1804
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 540,
                "End": 858
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2111,
                "End": 2185
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 927,
                "End": 1021
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 257
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 170,
                "End": 186
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2114,
                "End": 2188
            }
        ],
        "ipr_mapped": [
            7,
            233,
            45,
            29,
            30
        ],
        "response#1": "NFEKSNFEKSNFEKSEKSNFEKSNFEKSNFEKSNFEKNSEKNSEKSEKNSEKNSEKNSEKSEKNSEKSEKSEKSEKSEKSNFEKSEKSNFEKNSDFEKSNFEKSEKNSDFEKSNFEKNSDFEKSNSDFEKSNSDFEKSEKNSNFEKSEKSNFEKSNFEKSNFEKSEKSNFEKSNFDFDSNFDFDFNFDFDSNFDFDSNFDSNFDFDSNFEKNSNFEKSEKNSNFEKSEKNSNFEKSEKNSNFEKSNFEKSEKSEKSEKSNFEKNSDFEKSNSDFEKSNFEKNSNSDFEKSNSDFEKSNSDFENSNSDFENSNSDFENSNSDFENSNSDFENSNSDFENSNSDFDSNFDFDSNFDSNFDFDSNFDFDSNFDFDSNFDFDSNFDSNFDFD",
        "response#2": "MRRPRRRHRRPRTSAERRRLPRRPARLRRPARRRARRRRTARPHLASHAAPARHRPAHARRPTRRRGRPRRPRRPLRCRHTRSRFLNRPLRARPSLTARSSSPPFRKPAARAIRAATSPNSPSSSSVATSATSSSPATSATSATSATSATVAPTSRTSPTATVPPTSATPTSTPTPTPPAPARARPAPRPPRHRPARRHRPRPARRHHRRMRLLFQRLPRPVTPAPRRWRFPPRPPRPSPSSPSSHSSPSPSSSSPSSSSSSSSSSSSPSSPSSTSARLRESPLATAGVSVSSMPSGSRSPSLSSSSSPSRPSSSPSSSLPPSSPPSSPPTSSSA",
        "response#3": "RGYGEQEHGPHQPTPSSTPPSAPTPTSSSSSTTTTTTTTTTTTTTPSTPSTHPTTPPTPSTPPSTPSTLSTPSTPSTPSTPTTPTTTPTTPTTTNTTRTRPRPRDPQLHRRFHTTPHPRPRHTHHHRRPPPPAEARHLRTTPPRPPWRPDTRRRRLRRPSTSKAGRRARRRRRLDLTQRREKERRRRERLVPRRRRRALRRR"
    },
    {
        "reference": "MISTPEPLHAGHILTPFCCGVDSIDNWLEQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDPIPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLVESV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016747",
                "GO-Name": "acyltransferase activity, transferring groups other than amino-acyl groups "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 151
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 151
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 85,
                "End": 143
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MTQGTGRRATAGRRAHPVTRRAHPRGPAPTPPPVDRARPPVPVPAPAPAPAPRPAGPVAVVRHRSGRAVVALTGGTTARCLADGTVTRLPLAASTDPERAAAARRAAAAAPARPEHRPGRGPGGPAPTGHDRTGPGAADRAGPAGRDRPGPGRTAPGRTGPAGHARPPRSGPAAPRRDRARPPRSGPAAPRRDRARPPRSGPGRTGPGAAPRPPDAELAARLDRLRAAAAALTPGVRRP",
        "response#2": "MSSSSSSPSPSSSPPPPSPSPSSSPPPPSSPSPSPSSSPSPSPSSSPPPPSSPSPSPSSSPSPPPPPSSPSPSSSPPPPSSPSSSPPPPSSPSPSSSPPPSPSSSPPPPSPSEREREERERERIRRREREREREREREREREKEREREKERERERIRERIRIRRRRREEEEEEEEEEEEIEEREREREERERERRIRERIRIRRREREREGERRRRIEEREREGERERRRRRRREERERERERERLRQEIEELEQQIRSFIQEQIRCENEKIEKLVAATFSFTL",
        "response#3": "MTPTHTPRPPRPRHAPTHTPPPHTPRDAHAAHHALHDAARAHAALPPLTDPRLLTDPRTLARLAAALATALHTHTPHTDPHLLTAAQHRALHDALHHLTATTHTALHTAHALHTAPHTTPHTALDALTRTLPHTAPHTPPPTRLHATLHTALHVARHTTPHHTPTHPRHTPPTHTHHTRPDSPTSTPHLTHTLHPHTPSHPHTHTHTHPHAPRTPHPPHPHPHTPTTPRPTHPHPHPPRTPRTHTPPRPARPHPPPATTPRPTHSHPHAPRTPRPSTHTR"
    },
    {
        "reference": "MAIKLIVGLANPGAEYAATRHNAGAWYVDLLAERLRAPLREEPKFFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMASFYRIQPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Pept_tRNA_hydro, Pept_tRNA_hydro, Pept_tRNA_hydro, Pept_tRNA_hydro, Pept_tRNA_hydro that shares evolutionary origin and functional similarity; 2. The protein should be classified within Pept_tRNA_hydro_sf, Pept_tRNA_hydro_sf sharing conserved structural features; 3. The protein should contain Pept_tRNA_hydro_CS, Pept_tRNA_hydro_CS that is preserved across related proteins; 4. The protein must be able to perform the peptidyl-tRNA hydrolase activity,tRNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004045",
                "GO-Name": "peptidyl-tRNA hydrolase activity"
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": "tRNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004045",
                "GO-Name": "peptidyl-tRNA hydrolase activity "
            },
            {
                "GO-ID": "GO:0000049",
                "GO-Name": " tRNA binding "
            }
        ],
        "go_f_mapped": [
            109,
            138
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR018171",
                "InterPro-Name": "Pept_tRNA_hydro_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 110,
                "End": 120
            },
            {
                "InterPro-ID": "IPR036416",
                "InterPro-Name": "Pept_tRNA_hydro_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 192
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 182
            },
            {
                "InterPro-ID": "IPR036416",
                "InterPro-Name": "Pept_tRNA_hydro_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 194
            },
            {
                "InterPro-ID": "IPR018171",
                "InterPro-Name": "Pept_tRNA_hydro_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 16,
                "End": 29
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 189
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 176
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 186
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 176
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018171",
                "InterPro-Name": "Pept_tRNA_hydro_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 110,
                "End": 120
            },
            {
                "InterPro-ID": "IPR036416",
                "InterPro-Name": "Pept_tRNA_hydro_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 192
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 182
            },
            {
                "InterPro-ID": "IPR036416",
                "InterPro-Name": "Pept_tRNA_hydro_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 194
            },
            {
                "InterPro-ID": "IPR018171",
                "InterPro-Name": "Pept_tRNA_hydro_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 16,
                "End": 29
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 189
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 176
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 186
            },
            {
                "InterPro-ID": "IPR001328",
                "InterPro-Name": "Pept_tRNA_hydro",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 176
            }
        ],
        "ipr_mapped": [
            265,
            266,
            267
        ],
        "response#1": "MLLFVGLGNPGAKYAGNRHNIGFMAVDEIHRRHNFSPWKKKFQGETSEGFLAGEKVLLLKPQTFMNLSGQSVGEAARFYKLAPADITVFHDELDLAPGKARLKFGGGHAGHNGLKSIDAHLGTRDYRRVRIGIGHPGDKALVSNYVLGDFAKSEQEWLGPVLDAVADAAPMLVARDDNKFMNQVALALAGQERPDKGKKPKPGTEKPAPAPPPAPAKPRAQQAHRAQTRNKPKPAIPETGPMAEMLKRMFGKKD",
        "response#2": "MPEAPRLPERLALALERLRRAAPPLPPEELRRALEALAALPRLRGEDAAAWAAGPPPARARLRYEGPGRWVLEVEAAPGGRALARFELERPLPGEAEEWAEVLRAVAPHLRGRAAPPEAARRLREALARALRAERLREEAERALREEAARLAPEAAERVRELLRAAPGPEALPAAAPAPPPPPAPAPEAPPPAPAPPPAPAPSEELPGLLLALAAALGLRPEPGPPPPAPPPRAAPPSPAPAPAAPPPAPAPPWEEAERVREAAEALRRAAEAVRRWREGPLARELRRLCRGLRPEAVEERLRRAAEAPPLPARARPPPPPPPAPLSPEEREALARALLERVPGPSGPEERRAVRRAVEEVEAALEARAAGPPLPPPPWVVA",
        "response#3": "MRLIVGLGNPGPRYAGNRHNIGFMAADEIHRRHRFGPWRKRFQAETSEGEIAGERVLLLKPQTFMNLSGQSVGEAARFWKLAPADITVIYDELDLAPGKARLRLKGSAGGHNGMKSIIAHLGTQDFRRIRIGIHHPGDKSRVAGYVLGDFAKAEQEWLDRLIDHCADNAEALVRREDSRFMNEVALSQPPPAKPEKPAPAAKPAPAPAPAPAPAPAPPAPAPPAPAPAPAPPAPAPAPAPAPAPAPAPAPAPAPPAPAAAPPPPATAPAPAPAPAPAGLLSRLRAKKPAAKPPAAPPAAPPAAPPAPPPPPPATPPPPAPAPAKPAPKRTLPETGPLRDLMDRFK"
    },
    {
        "reference": "MISETFCKSSADEGYTSFPIRPTSIDRPVLDKTSQCEFALFPHFCNIHTLSTLSNASWALIAGQLTNSTKIILGVPSSGESTPVHDIESRTALQPAAVPLLIDWRPEQSVADYLNHVQSRIADATALDGASSQLLAGGFPGDNYARHIQTLIVVETIETSPGSINGTQKLQRLEYDHKKNSACATLVIEMRLQKTGIMADASFDTRALGPWLVYNLLKRLEYVMKQLCCVSSGHVLADIDMITPEDLEQIWQCNDPIPAPVERCMHDVVQERCRLQPNALAVDAWDGRLTYRELDQLSDRLAGRLVNQGIEPDMLVPLCFHKSMWMPVTMMGVLKAGGGFVLLEPSFPEQRLRAMVEEIKPSIILASSTTRALSLRLLDNVIQVDSELFNYPNPSANGFPQLQPSSTAMFGVFTSGSTGKPKGAILTHANYCSAFTYQLDLLGFKKDSRVFDFASYAFDVSVHNVFASLASGACLCIASEEERRQDICKSISDMRATIVHLTPSVTRLIQPEKVPLLQTVIFTGEPLSVEDVKPWWGKVNIVNEYGPAECTINTINSNPSSPEEATMIGKGVGVAVWIVDPNDHDLLAPIGSVGELLIEGALVGRGYINETERNAAAFIENPKWLLHGRPGRPGRQGRLYKTGDLVKYGEDGNLIFVGRKDTQVKIYGQRVDLREVEHWIQSCGHGAGQVVAEMIAPRADDPAPALVAFLQIGHTGLGGPLCPNSTEATLRPVPDEVEAKLAKHLPSYMVPKMFIAMSQFPMTATGKTDRRQLRKIGSSFSLEQLAEVRAKARGRLERQPLTGMERLLCDVWSKVLRLERRTIGPESNFFHLGGDSIAAMKSVGEARKSGIKVAVADVFRHPSLQDLSRQSRYIEDNSLDHIEPFDLLGEVFNRVSFLKDASHQYGIDPSAIYDAYPCTPLQEGLMSLTAKRPGDYIEQMILELGGDVEVDNLWVAWDHVARVTPILRTRLVHHNDLGLVQLVLEENTSRTDATGLDEYLDADRRRSMSLGEPLSRYGLVRNETGEPKWFVWSIHHAIYDGWSVQLILDAAYRAYRGEKIQQGPQFQVFIKYVQQQRHHNQGRVVEYWQKTLAGFKGTQFPSVVPSVQQPVADTSLCCCIPNPQNSRVGVTTSMLIRAAWALVVGTMANSEDVVFGSTLYGRNASVAGLEELAAPTIATVPVRVRFSRNQTVSEYLEAIQQEATAMIPFEQTGLQEIAQISDSCQMACQFQTHLVIQPEEHAQGKGPLGTWQIRSQEQWFSTYSLTLELWLGTDHITASAMFDSRIIESWVVRSMLQRLEGVMYQLNYATSSQLLGDITILTTEDLEQIWEWNKTIPTPVNRCVHEIIHDKVQARPNAPAICAWDGELTYNELNRLADQLSGRLTELGVGPHLLVPLCFEKSLWTAVAILGVIKSGGGFVLLDASLPEQRLRSIMQQVKGDLVITCPSQQALCSRLGAQTITLSWGFFSTLRGYEAGLRIQEYSPSSILYAVFTSGSTGTPKGVLITHGNMASALHYQSEAMGLSEDSRLYDFASYSFDVAISNIFTVLAAGGCLCVPSEEHRKNNLEGSIISLRANALDLTPSIAQLLSSARLLNVRSLTLGGESVLATAAEPWFGKLQMRNAYGPSECTPTCIINHNPSSPEQATEIGNGVGVVTWVVDPSNHEVLLPPGCTGELLLEGPLVGPGYLGDGEKTAAAFIHDPVWLTKGTHNRTGRHGRLYKTGDLVKYNKNGTLSFVRRKDTQIKLRGQRVELGEVEHVLRSHSCVVDAVAVSQRDDKLGAWIAGFVTIRADGQKKHQGDGEYEQQQIQSWEDQFDGETYTSIEAMPREAIGRDFIGWTSMYDGSDIDKGDMNEWLDDTINTILDGGPVGHVLEIGCGSGMMLFNLANKGLQSYIGIEPSRRAVDATTRIANSIPNLKERIRIVKGTGEDLQRLGTRLGTPISPDLVVINSVIQYFPSQEYLVKLIQDIFKLGSVKTIFFGDVRSHALHKEFLALRALQILGETASREEIGQVLSNLHRAEPELLLDPEFFTSLPARLPGHIAHVEILPKKMEATNELSSFRYGAVVHLDLEHRQTPDIDPKSWVSYTSRGLDCKSLLALLKNRPEAADTIAICDIPHSKTVFATELIDDLENGASEARHSRHWAQFICQKAKQRSSLSAIDLVKLAEEAGYRVEISWARQYSQRGGLDAVFHRCIADNDARRVLFRFPTDHTDRPYHFLSSKPLRRQAEIKIQKELEAKLRCQLPSHMIPQTITILDRMPANHNGKVDRQILADSVQRQWTGRGRRRSPTTDMEKELQRIWSHVLNISPDSIGLDDGFVHLGGNSLNAMKIVHMARQAGIDLTVADMFRYSETTIERLLLDCCCDDTCGKGTSADAVNWTYLMAAIDERDAYLAAIQAGEKSHLVNGDMQADSDNLLTVLLTGANGFIGTQILRQLLEHGRVDRVICIVRGESPSVARQRTIEAAKKALWWTEFHQEMLEVWPGDLSLPRLGLDEVKWRLLAEGKAANIIIHNGASVNFVKSYAALEAANVDSTVEMVSVVTRNPSMRLIYVSSARSQDPMEEEEEDMAQALTKNPNGYNQTKFIAEALVRRAALRTSPRQDQFMVVSPGLVVGTPTEGVANADDWLWRMAAACIRVGVYNVDNSDKWVPLCDVSTTATVIIEAALGHPSTSRTVTQVRGGLTMGEFWETLAAAGYPLVGTRVAECTAAIQEDILANGENHPLGALADMLQDLEDTTNVQWADSWRKNGLCSPARLKAALCKSAEFLSRVEFLPSPNLVHGRVVQETNMRAFTRSGF",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PKS_PP-bd, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf, ACP-like_sf, SAM-dependent_MTases_sf, ACP-like_sf, SAM-dependent_MTases_sf, NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the methyltransferase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016874",
                "GO-Name": "ligase activity "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            20,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 799,
                "End": 869
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 798,
                "End": 870
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2288,
                "End": 2362
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1842,
                "End": 2025
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2290,
                "End": 2353
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1827,
                "End": 1977
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2322,
                "End": 2337
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 831,
                "End": 846
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2296,
                "End": 2356
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 805,
                "End": 871
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2290,
                "End": 2368
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 799,
                "End": 875
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 807,
                "End": 869
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2298,
                "End": 2353
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2420,
                "End": 2696
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1744,
                "End": 1820
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 799,
                "End": 869
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 798,
                "End": 870
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2288,
                "End": 2362
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1842,
                "End": 2025
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2290,
                "End": 2353
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1874,
                "End": 1971
            },
            {
                "InterPro-ID": "IPR013120",
                "InterPro-Name": "Far_NAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2423,
                "End": 2656
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1827,
                "End": 1977
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1369,
                "End": 1771
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 290,
                "End": 683
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2322,
                "End": 2337
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2172,
                "End": 2284
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 661,
                "End": 780
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1336,
                "End": 1742
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 831,
                "End": 846
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2296,
                "End": 2356
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 805,
                "End": 871
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2290,
                "End": 2368
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 799,
                "End": 875
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 807,
                "End": 869
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2298,
                "End": 2353
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1350,
                "End": 1689
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 270,
                "End": 607
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2420,
                "End": 2696
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 263,
                "End": 660
            },
            {
                "InterPro-ID": "IPR010080",
                "InterPro-Name": "Thioester_reductase-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2420,
                "End": 2738
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 914,
                "End": 1328
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 906,
                "End": 1088
            }
        ],
        "ipr_mapped": [
            70,
            7,
            45,
            46,
            29,
            30
        ],
        "response#1": "RGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVRGDAVDARRVDARRVDARRVDARRVDARRVDARRVDARRVDARDARRVDARRVDARRVDARRVDARRVDARRVDAPPPPPPPPPPPPPPPPPPPPPPPREAAREAAREAAREAAREAAREAAREAAREAAREAPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPEGVRPDLPRPE",
        "response#2": "MKLTTTNTTTTITATTTTTTTTTTTTTPTNPNTTTTNTNTNTNTTTNTNTNTNTTTTTTTTTTTPTAPTTPTTPTAPTATTTTTTASTAPTAPAAPPPHPPRRHNAPRARALPPPPAHPAAPPRPPGPGPVGASPAQAARAGGGGGGRRGGRPERRGPGAARGRRGRGRGGGGERARARARAEPARARGRAHARRALRAPRPPRAPGRGRRPAPRRGPPPPRPPRPPRPRRPPPGPPPRPPPPARARADARARARARAGAPRRPPAVRPRPRPRRRRRPRRRPELPAPPRPNPPAWPRPRPRRGRPRPAPPGRARRRPARRAPPGAGARGLRCPRAQGPRAAAAGRVQGARGPRGPRGPAARARAACPQARASAAAVRGGPADPGGAGAEAELSA",
        "response#3": "STAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTARDVSTAREDVSTAREDVSTAREDVSTDVSTAREDVSTAREDVSTAREDVSTTAREDVSTAREDVSTAREDVSTDVSTAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTARDVSTAREDVSTAREDVSTTAREDVSTAREDVSTAREDVSTDVSTAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTAREDVSTDVSTAREDVSTAREDVSTAREDVSTAREDVSTDVSTAREDVSTAREDVST"
    },
    {
        "reference": "MVNLDFEVEPCLFPSLSTRSVNQSHGKAMAYQHGFEWEVTISEDSVFQGIVLSWNILLAKYTDSTTITFGVISGSEGNKCHDDTTVDEYCTSFHPESCLPTVLPLASRRQYRFHEWKYDARINTCIANGSHKVWLDHWINSPNHGIKLILVVEQGRWPCMSLYGKPSFIDEGSVRLLCTAFQHILDCVLENQMGLLKNIEVTPSHHYQRILDWNSHIPKEPLAECIHDLIQRRCMETPDAEAICAWDGTMSYAALEQESARTMEWLQHHGVGPETIVPLLFEKSKWTVVAVLGVLKAGAAFVLLETSHPIERLKSICHDIGACIILTSALCKEIGSNLADITMSVPCDVERKLPCGDGKMKPCIRAQPRNAAYVAYTSGSTGKPKGVIIEHASFCTNAMVSSEAQNLNGCSRVLQFASYAFDVSIHETLVPLMLGGCVCIPSASQRVNSLQEAIVQLRVNWMELTPSVTRLLSPHKIPNVKTLVVGGESISPAELARWAGHIRLNVAYGPAECTVVSMVQSNVTKHGDPLSIGRGCGGSVWIVEPQNHNVLVPIGAPGELLIGGPIVGRGYLNRPEQTAAVFIQNPPWQAENNSRFYKTGDVVRQNSDGSVVFLGRKDTQVKLRGQRIELGEIEYQASGFFPGAAVAVEVGKLYHGHPALVLFVEWKSLENRKRCSGTNCCRTVQNDKTHFMSNAQWAKAGLSQILPSYMVPDIIVPLCTIPLSHSAKVDRKALRAMITRWSKDEVKLYQVTANSTSCGRYPHHAGQKYDEMVRMVARVLSLDPSEVREHDNFFQLGGDSLSAIMLSREIDTIPLLSLTVADIFQSASIAELFHRSQKTPLPESMEPGIPTKVLPFSLLDPMKIDNYRERAAEHCGVSPSQIEDIYPCSPLQARLMARTSRQPGAFQGHFNFRLSLDTDWDRLHWAWNKAADFLPILRTRIINTWQLAEGNPLQVVVRDKDIEWVEVAASESEPKSRMSFGSPLIYCVAVRAKHSPVLILNIHHALFDLVVFEQILEAVKAAYQGKPLVWRPFSPFIKYVQDLNRSQANEFWKREFTGLRAVPFPADITPGRSNLDAIRWTRKSFCLGHQNQAGITLSSLIRLAWAMVLSQYTGSLDVVFGTTVMGRNMPGTADVGGPTIATYPLRITLRGEESIKEALQRIQNHGIAIAPFEQSGIQHIRHSSPESAIACSFRNMLVIQPSSDNSLLAKRDLSPLLVLEERGSWKQKSYVNFSTQALNVVCEPGAGHLDVSAYFDQSILSSQEVEEMLSCMDRLLQLVLQHPDASMGTILSQSQSPDGDLDRYEERTSLARLEQEACQYLGNGVRVAAVWIIPMASHVPKLALFVGAMSLNTVSDGRWILAGVKEPLRTRLVQMMHEFQNNPLGRAVPFCCIPVPLQYRPSMPGLFLDRARAQEAASKFTLKTLTSWQNTGDSGFEEPLLPLEATLRRALAKVLSLEPEAIGVNDDLVSLGCDSLVAMQFAAQCDRQSLRLTISEIFQATSLRCLASTLNSRPSGDPTPALEAFALLKPMYGDRESFEQDIQRSVDGWNIKESIDAFPCTTAHLGLLSGLGTCQSHTIWEIGSPEEQIDLVSFAKAWLNLVNRHAALRTLLLPSRSNPSEWLHVVLKSSPVGVKVVTKLKNASLLKIARKPLLSRDGLGGLPYRFAVYQSTTGRTLCKLEARYAFLDAFSVLVLMKELRRILDCLPTSDPLLPSYSSWVAYLRRWSEDPLHLQFWDRYLAGLKPCILRASRNHHHHQHEGRQHHGASETNGNRPRLIKSHRQIVVQDAVALRKYCDQRELTITNILQVAWALTLKEQTGIEDICFGALVSGRDVPVDHVGNIVGSLFNVLACRIQMPATDSISSVLLENQQMMRERASHQFCSLQEVTRLVLKARPEASSLFNTCLSVEQPLSDEAETGKGFRALETVEETEYDLIVAATVFPDRIQASIMYWSYFCDPARAATIAETFAQSIERIILCA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016874",
                "GO-Name": "ligase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1438,
                "End": 1514
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1446,
                "End": 1508
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 772,
                "End": 832
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1442,
                "End": 1524
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 768,
                "End": 833
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 769,
                "End": 834
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1438,
                "End": 1509
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 763,
                "End": 840
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 795,
                "End": 810
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1444,
                "End": 1514
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 769,
                "End": 840
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 224,
                "End": 617
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1438,
                "End": 1514
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 251,
                "End": 638
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 618,
                "End": 747
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 883,
                "End": 1293
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 1586,
                "End": 1978
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1446,
                "End": 1508
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 772,
                "End": 832
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1442,
                "End": 1524
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 768,
                "End": 833
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 231,
                "End": 572
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 769,
                "End": 834
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1438,
                "End": 1509
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 763,
                "End": 840
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 875,
                "End": 1060
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1556,
                "End": 1733
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 374,
                "End": 385
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 795,
                "End": 810
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1444,
                "End": 1514
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 769,
                "End": 840
            }
        ],
        "ipr_mapped": [
            46,
            45,
            29,
            30
        ],
        "response#1": "MSFGAESDTAARVKKIVAEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGTEIPDDAAETILTVGDATKFLDKAEKAARPGRRRAGGAPGRARGRGRGRRRPGRRRRRPRPRPRRPRRSPHRPRRLPRRRPPRGPRAPAPRARRRPPPPHPRRAPPGRGPPPAPRGRPPGRRGRAPRGRGPPPRRRRPPAPRPRRRPPPARRRPPRRRRPPRRRRRRRPRRRPRRRPRPAPRRRRRRPPRRRPRPRPRPPPRTPRRRPPPPPPRRPPPPPAAPPPPPPPPPPPPPPPPGPPAMSFGAESDTAARVKKIVAEHLGVDADKVVESASFIDDLGADSLDTVELVMAFEEEFGTEIPDDAAETILTVGDATKFLDKAEKA",
        "response#2": "MSAAEIAERVKKIVVEHLGVDADKVVPEASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLADAADKLKPDEKRRRESRPARRRGGPRPPPAPGSARPGRPAGRARPGRRAPGDGPERGRTMSAAEIAERVKKIVVEHLGVDADKVVPEASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTFGDATKFLADAADKLKPDEKA",
        "response#3": "MSTSDDIGARVKKIIVEHLGVEADKVVESASFIDDLGADSLDTVELVMAFEEEFGIEIPDDAAETILTVGDAVKFIEKAQGGEPPPGEPGTSRPPGPEQPSTGEDFTPSTPSQPSQPSTGEDFTTGTPSQPSQPSTPSQPFTQPFSTPSQPSTPSTPSQPSTPSTTRIGTGRTKEVSTMSTSDDIGARVKKIIVEHLGVEADKVVESASFIDDLGADSLDTVELVMAFEEEFGIEIPDDAAETILTVGDAVKFIEKAQ"
    },
    {
        "reference": "MASEIYRRLPMELPAQHLLASLALVGALLSVGYLLLRPAKYQLPLPPGPRGLPIIGNLHQAPKEKAWEVYKQWSDRYGPIMSVNNGGMITIIVSSHEVVKNFLEKNNAVFSSRPQLLVLERALYGFTTPALPYGEKWLKHRALRGAVLKPAMAVRYRGLQDLESKQLLRDLLYSEDFTQCMRRQAASLFLGIAYGNRFPEETPEIIDIDQAVAQLGGISESMFQGTGMLREFFPVLKYFPGYDKFLKQLDDVGERLANIYVRRFRDGLSTPAWNWAKEYSKRPEAQGMGELELSFCIGSTYQASLTPYEILRIILLAAICHPEEKARLQKEIDLVVGKDNLPGWEHKDRIQFVQAFIYEALRWHAFSPLGAPRAVSRDIEYKGYFIPKGATLVLNQWAMDHDENVYDNPFTFRPQRWIDNPDLPHVIFGFGLRGCPGQHLARDHLFINTARLFWAFNFGNAYENGKKVELDLDELMQPRGGGSAFNQVPSFKASVIIRSSERRQIVENEWDAVEKDEQKILAEAMPLPE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 446
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 333
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 435
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 366
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 37,
                "End": 479
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 46,
                "End": 467
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 46,
                "End": 468
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 395,
                "End": 419
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 98,
                "End": 119
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 337
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 372
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 74,
                "End": 93
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 184,
                "End": 202
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 458
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 425,
                "End": 435
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 428,
                "End": 437
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 446
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 333
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 435
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 366
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 37,
                "End": 479
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 46,
                "End": 467
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 46,
                "End": 468
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 395,
                "End": 419
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 98,
                "End": 119
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 337
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 372
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 74,
                "End": 93
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 184,
                "End": 202
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 458
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 425,
                "End": 435
            },
            {
                "InterPro-ID": "IPR050364",
                "InterPro-Name": "Cytochrome_P450_fung",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 517
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 428,
                "End": 437
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MRLSSRIFLGEPLCRNEEWLDITATYSGNAFLAAMELRYWPEFLKPKAYRARARVRELLVPIIEERRAAKAARAAEGLESYNDTIEWFEEVAKGRNYDPALAQLSLSLAAIHTTSDLLTQVLFDLCAHPELIQPLREEIIRVINEHGWKKTALYNLKLMDSVLKESQRLKPIAKVGMRRKAIEDVTLSDGTFIPKGTKVAVAAYAMWRDESNYPDADKFDGYRFYKMREVPGQENSAQLVSTSPEHLGFGHGKHACPGRFFAANEVKIALCHILLKYDFKLEEGAKPKNVGMGIFISADPAAKVLVKKR",
        "response#2": "MTWIAKQFAADSIAAAEELRIYPAFLRPVVAWFLPACRKLRRELAVAREMIAPVIEERRAARARGEKVNDMLQWFMDVAEKTRPSETYVDRLVHRQLTLALAAIHTSSMSLVHVVFDLCARPELIQPLREEVVRVIKEHGGWKKTALYKMKLMDSVMKESQRMNPVAVVSMHRVATQDVTISGHHIPKGTKIGVAAYPMGRDPSIFPDPEKYDPYRFVNPDNPNSQFVSTSPEHMPFGHGRHACPGRFFAANEIKIALCHLLLKYDWKLAEGSPRPKNMKSGGFILVDMNAKVMLRRREEV",
        "response#3": "MEERRKKRAAGETPNDFMQWVMDTAKTPAEATDETIVHRILVLNFAAIHTSSMSMTHTLFDLCARPEYIQPLRDEIVSAIDQHGGWKKTALYNMKLMDSVLKESQRLNPPVVLSMHRVAMEDVTLSDGTFIPKGTRIAIAAGPMHRDERIYPDADKFDGFRFARMRENGNNGSKDEMSSDAASPGASAQLVATSPDHLGFGHGKHACPGRFFAANELKIALCHILLKYDFKLREGEKPKNTSYGFFIMADPDAKVLVKKR"
    },
    {
        "reference": "MSLISPLAAVLSAMAIVLGLLFFPNMTPQPTLHPRVGWRKEKASTLRAALRSCYKLNDWALEGYNAYAKLNIPYVLPSFDRGPITIIPARLMRRLYTLPDTDLDIRMTQQETNQTRWVAWDKKPAEDTFVWDVLRKQITRNLRQLTPIVASEIELSFNRWWGTDKEWKSIDIWDSCWKIVTGGINTTLCGSPLCRDAEFLQSCQNHSLVLVAGAMAINGAPRLLQPIIGGLVWFVCAILFNTTMKRSKAVVQERLEKTAMLRAEPAYDWKPPQDAIQWIIDDLYASDNLTQLNVKTICFRLLLLNDVSIPSTSFSVQTLLLNLFAADPALGFLEALREECQTVYTESGGVWTYDALKKLKITESAIRESLRLSPVGGIGLHRTVVNPKGISLPDYRLNLPHGTVIASPIESIHYDDDIYPHANDYNAFRFADPEAVRAILDKLSSEPNSNISTGGPRDRESKSAASTANIDEAFLAFGIGKHICPGRFFVMVEMKLILAIILVHYDVKPVKFKPKLVDCLWLKVPWNSGTLVVRRRSN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 468,
                "End": 484
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 484,
                "End": 502
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 359,
                "End": 375
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 131,
                "End": 513
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 477,
                "End": 486
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 127,
                "End": 536
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 87,
                "End": 528
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 468,
                "End": 484
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 484,
                "End": 502
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 359,
                "End": 375
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 131,
                "End": 513
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 477,
                "End": 486
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 127,
                "End": 536
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 87,
                "End": 528
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "MAHAQLVLSVAAIHTTSDLLTQTIFDLCARPELVQPLREEIISVLKEEGGWKKTALYKMKLMDSVLKESQRLKPVNRVTMFRMVTEDIKLSDGTVLPKGTKVGIAAHKMWDASKYPDPEKFDGYRFVRMREQPGKEENAAQLVSTSPDHMGFGLGKYACPGRFFAANEVKIALCHILLKYDWKLDDGSKPRNGNCGIFLSSDPNARIMVRRREEEISFE",
        "response#2": "MAVLVESLIPLLLNSTILLVVFALSTLVYLSTASSKKSSKRLPPGPWKLPIIGNLHQLGALPHHSLRALADKYGPIMHLKLGEVSTVVISSAEMAKEVLKTHDLSFANRTKVEAMRIMGYDRKGLVFSDGEYWKRQRKICTSHLKSNGKDGSEDMVMKLVDNEKISHDNIKAVVLDMFIAGTDTSSSTMEWAMSELIRNPRVMEKAQEEVRRVIGEKGSVEESDIPNLPYLQAVVKETLRLHPPAPLLIPRESREDVKVMGYDIPKGTKVLVNAWAIGRDPRIWENPEEFMPERFENSVDVKGKNFELIPFGAGRRICPGLPLALATVHLALANLLYSFDWKLPNGMKPEDIDMSEKFGITVHKKTPLMASPVKRLYSFR",
        "response#3": "MPAKDTVLRLVAQLSSRVFVGEELCRNEDWLKITVDYTVNVFKAAEELRIWPEILRPIVHWFLPSCKKLRTQIEEARALINPVLEERRAAQKANPDKKYNDAIQWFEDTAKGKSYDPAIAQLRLALVAIHTTTDLLSQTILDICARPENQELIQPLREEIIRVLNEHGGWKKTAIYNLKLMDSVLKESQRLKPVKLISMRRIATKDVTLSDGTFIPKGTKISVAAHAMWDPDIYEDPEKFDGYRFVRMREVPGQENSAQLVSTSPNHLGFGHGKHACPGRFFAANEVKIALCHILLKYDVKFEEGAEPKKLNSGIFNLADPSAKILVKRREEV"
    },
    {
        "reference": "MTLQPTAADVGAMYDQYTSLLTDVMAGFIHVGYWEDPSSEETMEVATERMTREVGARLSSSAGQHILDVGCGTGKSAVQIANTHGVQITGITVSKSQIEEAQALYGSAVQAGQVSYQFANAMDLPFADASFDGAYAIESLVHMDDRRTALQNIARVLRPGSRLAIADLCLDAHCPNPEALARFHELFQVPPMSSGEELQELLRETGFRVLEFTDIRDNVRPVCKFLEKKALSLEGEVGEKLLEIATSMATLKELGYAFITAERI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 221
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 264
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020803",
                "InterPro-Name": "MeTfrase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 21,
                "End": 264
            },
            {
                "InterPro-ID": "IPR013216",
                "InterPro-Name": "Methyltransf_11",
                "InterPro-Type": "DOMAIN",
                "Beg": 67,
                "End": 165
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 221
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 264
            },
            {
                "InterPro-ID": "IPR050447",
                "InterPro-Name": "Erg6_SMT_methyltransf",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 219
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPEDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSYSNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLLDDTGQVTWLREDGFRFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGVNAQIQARQLYHDREEVTVHVRRIWP",
        "response#2": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYELYQPGDGEKLIRELPFSFAGRFLVVGELLQKELPENCRKLTVPLRAALREAGVLAENETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRFRPTRSNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAPVR",
        "response#3": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYELYQPDDGDKLIRELPFSSLIFARQWLVVGELLEKELPKNCRDLTVPLRAALRDAGVLTEYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
    },
    {
        "reference": "MSIVKEAHNVKVLGSGEKTIVLGHGFGTDQSVWKHLVPYLIDEYRVVLYDNMGAGPTNPDYFDFHRYSSLEGYAYDLLSILEELEIKCCIYLGHSSSAMTGVVASIFRPDLFSKLILVSASPRFLNTDDYYGGFELEEIDQLCQAMESNYKAWIAGFAPLVVGGDMDSVAVQEFSRTLFNMRPDIALSVFRTVFTFDLRHFLSQVTVPCHIIQSSLDVAVPVAVSQYLHQNLGGMSIVEIISTEGADCFGSYRRGSEMETKRGSDDAVTIALR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AB_hydrolase_1 that are essential for its biological function; 2. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 10,
                "End": 240
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 249
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 227
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 10,
                "End": 240
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 249
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 20,
                "End": 227
            }
        ],
        "ipr_mapped": [
            35,
            36
        ],
        "response#1": "MTTRTLTAPDGTPLHVTAHGTGPAVVLVHGLGVDHTVWDPLIPHLARHHTVLAPDLRGHGRSGRPDPARTTVADHVADLDCLLDATGIRRAVVVGHSLGGMIALGHAAHRPDRVAGLLLLATTARPTPAATPAATPAATPAAAPAPAAAAPSTPAPAAAPAPAPLPPAAPRARRAAGLAALRATVTGDTGAYARTLIDRILAAPATPAAVRAAVETTIAATDPAGYLACCTALLDHDLHAALAATTVPTALLHGTTDQLIPAAATADLPPTVTRRDVPGAGHLLPLERPAETAAAIRTLTEETR",
        "response#2": "MTTTTTTTTTTTTTTTTTTTTTRLNVRTVGTGPDLVLLHGVGTDQTSWSAVAPLLARTHRVTLIDLPGFGRSPPLPAGTTGIDEFADAVATALTAAGVTRAHLAGHSLGGMIGLLTAVRHPGLFAGLTLIAASPRFLADADDYGYGHPEGYTEEEIDATFAAVETDFTAWSAGFATVAIGPTARTGDPEAVRWCTDKLFGLRPDIALAAARTVFTADTRALLPCVTVPTTVLQVGRDIAAPPAASRYLARHIPGARLVELDGIDHLPQLSAPAAVAAAITTTTTTTTTTTTT",
        "response#3": "MTTTTPTTPTPTTPTPTTPTTPTTTRTTVPTPTGRLNVRVLGDGPRTVVLGHGFGTDQSAWSRTAPLLAERHRVVLYDLVGFGDSDPDPAGRHTLDDHVDDLVGVLDALGLTRCAYVGHSVSAMIGVLASIRRPELFSRLVLIGASPRYLNDTDDYHGGFEQEEIDEVFAAMEANYQAWSASFAPVAVGTAEDSPAVREFNRSFLRMRPDIALSVCRTVFLSDLRAVLPTITVPTTIVQVTRDLAVPLAVSRYLHRHIPGSRLVEIATADHLPHLSAPQETADAITEALTA"
    },
    {
        "reference": "MENQHQKFISRRNFIKTSALLGGTAFLGTGLPNIKKTYSKELDYVGNFEYPLAKPENILYSACLQCTVACSIKVKINNGVCMKIDGNPYSAMNLGENLPYDLSPKEAVSIDGKLCPKGQAGIQHAYDPYRLRKVIKRDGPRGSGKWKTIPYDQAIDEIVNGGNIFKDIGENQNVEGLKDIFVLKDPKVAKAMADDVTKIRKKEMTVDEFKAKHKDNLDVLIDPNHPDLGPKNNQFLFQVGRIHNGRIEFTKRFVNDSFGSVNWIEKTTLCGQTSNKAWVHSTREYLEGKWTGGIKSPRPDHRNTEFLLVFGSIVFEANYGPVQETEPITEGLESGRLKIAVVDPRLTKVASKAWKWVPIKPGNDAAFALGMIRWIIENERYDTKFLQNATRLAATNSDEPSYSNATYLVKVEKDGRAAKHLRANEIGIGTEKEFVVISNGKPAAVDPENSNLAIQGELFVDTNLEGIKVKSPLQLIKEEAYSKELAEWAELSGAKQKDIEDISKEFTSHGKKAAVEFYRGAIKHTNGWYNGQALIVLNHLIGNMNWQGGISNTGGGWSYIGDKEGQPYPMANLHPNKLSKFGVPITKEGWKYEESTLFEGYPAKRPWYPFSGNVAQETWPSISDGYPYKIKAALISSHSPMYSLPGGHVQLKTLLDTEKVPLLIASDIVIGDSSQYVDYIFPDLTYLERWATPGQSHHIRVKVNQVRQPVIAPLTENATVFGEEVPISLEALMMSISEKVGLSGFGKDAFGPGKDLNRMEDFYLKLVANIASGNKQGELVKAADSEEMELFKSSHRHLPKTVYDIEKWQQTLTSDEWKRVVYVLNRGGRFASSDDAYEGSFIKKKIPGLARLYLEEIADSRNSISGNYFTGYPKYLPIMDMAENLINDEGEFHLITNKEVFGTQSRTITNYWAQLALQPENFVVLNSVDAKKLKVDNGDKVLVTSTSNPKGEHLIAADESRPTIGKVKIVEGIRPGVVAISTHYGHWGYGARDIQIDGEVVKGEEVRGLGIHPNPLFRLDDNLRGTTLSDPIGGSASYYDTRVNIQRV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Mopterin_OxRdtase, Mopterin_OxRdtase_4Fe-4S_dom, MoPterin_dinucl-bd_dom, Mopterin_OxRdtase_4Fe-4S_dom, Mopterin_OxRdtase_4Fe-4S_dom that are essential for its biological function; 2. The protein should be classified within Asp_de-COase-like_dom_sf sharing conserved structural features; 3. The protein should contain TAT_signal_bac_arc, TAT_signal that is preserved across related proteins; 4. The protein must be able to perform the 4 iron, 4 sulfur cluster binding,cation binding,molybdopterin cofactor binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0043546",
                "GO-Name": "molybdopterin cofactor binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0043546",
                "GO-Name": " molybdopterin cofactor binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            79,
            183,
            157,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006656",
                "InterPro-Name": "Mopterin_OxRdtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 333,
                "End": 709
            },
            {
                "InterPro-ID": "IPR006963",
                "InterPro-Name": "Mopterin_OxRdtase_4Fe-4S_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 61,
                "End": 127
            },
            {
                "InterPro-ID": "IPR006657",
                "InterPro-Name": "MoPterin_dinucl-bd_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 892,
                "End": 986
            },
            {
                "InterPro-ID": "IPR006963",
                "InterPro-Name": "Mopterin_OxRdtase_4Fe-4S_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 56,
                "End": 129
            },
            {
                "InterPro-ID": "IPR006963",
                "InterPro-Name": "Mopterin_OxRdtase_4Fe-4S_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 56,
                "End": 127
            },
            {
                "InterPro-ID": "IPR009010",
                "InterPro-Name": "Asp_de-COase-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 886,
                "End": 1047
            },
            {
                "InterPro-ID": "IPR019546",
                "InterPro-Name": "TAT_signal_bac_arc",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 9,
                "End": 33
            },
            {
                "InterPro-ID": "IPR006311",
                "InterPro-Name": "TAT_signal",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1,
                "End": 39
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006656",
                "InterPro-Name": "Mopterin_OxRdtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 333,
                "End": 709
            },
            {
                "InterPro-ID": "IPR006963",
                "InterPro-Name": "Mopterin_OxRdtase_4Fe-4S_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 61,
                "End": 127
            },
            {
                "InterPro-ID": "IPR050612",
                "InterPro-Name": "Prok_Mopterin_Oxidored",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 1048
            },
            {
                "InterPro-ID": "IPR006657",
                "InterPro-Name": "MoPterin_dinucl-bd_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 892,
                "End": 986
            },
            {
                "InterPro-ID": "IPR006963",
                "InterPro-Name": "Mopterin_OxRdtase_4Fe-4S_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 56,
                "End": 129
            },
            {
                "InterPro-ID": "IPR006963",
                "InterPro-Name": "Mopterin_OxRdtase_4Fe-4S_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 56,
                "End": 127
            },
            {
                "InterPro-ID": "IPR009010",
                "InterPro-Name": "Asp_de-COase-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 886,
                "End": 1047
            },
            {
                "InterPro-ID": "IPR019546",
                "InterPro-Name": "TAT_signal_bac_arc",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 9,
                "End": 33
            },
            {
                "InterPro-ID": "IPR006311",
                "InterPro-Name": "TAT_signal",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1,
                "End": 39
            }
        ],
        "ipr_mapped": [
            746,
            755,
            757,
            758,
            759,
            763
        ],
        "response#1": "MPRRPDRRAAGRAAGPVPAVPEDRAAEGVRPAPVPAAAGDAPRAGTPAAEHPVVPVHAGAARPGGPGGPRGRPAVPVPALPAGPGAPDPRGPGRAGRHGGRGRGRGAVRGPARPARPVPGAAGPAGDRPAPAGRRASGRRRSPAPAAGRPVDGAPVGPDGARRAGAVPVRAPVPVRARGRRPAGVPGRGSAGPGGARRPAPGRAGDAGPAAGARAPGEPDGAGRAAAAGRRRPAPG",
        "response#2": "MGPAGTRGAEGRADPAQAGGPGPLPGGSAARGPQRVEGRPGADRRRPEAARRPGRAEGGRVRAAGGGPGAGAGAGSAGPAVGRAAQRRTRPGPGRAQGGPRTAVRAREPALAEEPGRGRPERERAAGRAEDRLPPDPGPHRAPEARGPPAGARALHPGAGPAGPRRRAGPRPGPGPGPGPGAGPAAGRRAPAAAARGPAGREPAPGRPAGHAGPATGRKPGPGAGRRPRPPGPARPAGR",
        "response#3": "MTKGKDGGKRGEREREKKKEKEEKKWKKKKMKKKRKKEGRERKKRERKERKEKEKRRKEEEKRKKRGGEAREEGGREGERRTRRRGKRGERGGGGEGGGGRGGGKERAKGREEESDKGREEGGRGEGKRKEGGGKKGKRRKKKRRKKHGKRKEGKNGKEEREGTGRKGGRERRRRKGRKGDRGKGKKKKRKKRKKKKRRRKKKGEKKGGREGERRKGERRRKEERREEGGEKKRERAKKGEGGEERERGEREGKREGKENGGEEEGAEKGEKRERKEKGDESKGGAGIRGVARGGGQRRKGGENGERDGGAGD"
    },
    {
        "reference": "MTGFLPEPLRMLVTSPALLDFTSDGPLPYALRQKFTGKPPPVTSNLSLASQTVLVTGATSGVGLEAARQLAQLGPRLLILGVRNASKAEQIKSELERDTPNLTVQVAELDLESLLSVDRFVDELSANSIRLDLALLNAGFFAHDDRITDDGYSPLFQVNFLSTAYLTLKLLPLLHTTAPPHPPGTTTPPGPRLVLVTSEAHAWTTFPDVPRPTENRTQPILSVFQDKNTLGSADDQYARAKLLLALFGKELSRRLTAAENDTTVVITTPGFCASNFFPDGMMTRLIQLTSARSVQQGGALHVFAATAPGPEIHGAYLRDGKPTGLSKFAQGPQGQILQERLWGEMEEFFMQRGGSPLGM",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 237,
                "End": 256
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 69
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 129,
                "End": 140
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 175
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 237,
                "End": 256
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 69
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 129,
                "End": 140
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 175
            }
        ],
        "ipr_mapped": [
            9,
            7
        ],
        "response#1": "MATAAPLVTVPLGHVPVTSSSSVRVNPQGKGGRRLTDKVAIITGAASGIGEAAAKLFIREGAKVVLADVQEDAGKALEKSLQEEAGSSGRAVFMKTDVSKETEVEALVAKAVEHFGRLDCAFNNAGIHGGSIVDSPEEDWDRVINVNLKGVALCMKYEIQQMLKQGVKGGSIINTSSVAGLVGVSSLPAYTASKHGVAGITKAAALEYAKQGIRVNSISPGFIETPMTSQYLKDEELNQWLISKCPLKRMGKPEEIAKAALFLASDLSSFVTGANLVVDGGYTAKHGVAGITKAAALEYAKQGIRVNSISPGFIETPMTSQYLKDEKDEELNQWLISKCPLKRMGKPEEIAKAALFLASDLSSFVTGANLVVDGGYTAK",
        "response#2": "MAAARLAGKVAIVTGAGSGIGRASALLFAREGAKVVVADVNEAAGEAVVEEIRQAGGEALFVRADVSREADVERMVAGAVERFGRLDVAFNNAGIEGATAPLHEMSVEEFDRVLAVNLRGVWLCMKHEIRQMLKQGHGAIINASSISGLVGVPEIGPYAASKLGVIGLTRSAAVEYAKQGIRINAIAPGFIDTPMQREILAKLPEEQQKKLVPEIGPYAASKLGVIGLTRSAAVEYAKQGIRINAIAPGFIDTPMQREILAKLPEAQQEKLLASTPLGRLGRPEEVASAVLFLASDESSYVTGVVLPVDGGMTAQVPGVE",
        "response#3": "MGRLQDKVALITGASRGIGRAAAVLFAREGADVVVNYNSNEEAAQEVVKQIESSGRKAIAVQADVSKESEVEAMVKKTVETFGRLDVAFNNAGIEGKRAPIHETTVEEWDRVIAVNLRGVFLCMKYEILQMLKQGGGSIVNASSMMGLVGMQSVSAYVASKHGVIGLTKAAALDYAKDNIRINSVCPGGIDTPMLEEVFKRSGRDDITIEDIRKQYESNTPLGRLGKPEEIAYAALYLASDESSYVTGANLVVDGGFTANV"
    },
    {
        "reference": "MSKIAQPTATDVGAMYDNHTDLMTDIMAGFIHVGYWEDPENPTETIELATERMTLEVLNRLRPSPGQHILDVGCGTGKTAASIATTHDVSITGITVSNHQIEVARKTYEALVETGKLNFQYADAMQLPLANASFDGAYAIESIVHMNDRRAALSNIARVLRPGSRLSIADLVLDDGCPDPDAIANWHELFQVPALISADKLKELLTETGFRVLECVDIRQHIRPICGVMDKKGLQVGGEVGKTLRGVAASLHGLEELGYILLVAERV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 226
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 267
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013216",
                "InterPro-Name": "Methyltransf_11",
                "InterPro-Type": "DOMAIN",
                "Beg": 70,
                "End": 167
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 226
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 267
            },
            {
                "InterPro-ID": "IPR050447",
                "InterPro-Name": "Erg6_SMT_methyltransf",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 221
            },
            {
                "InterPro-ID": "IPR020803",
                "InterPro-Name": "MeTfrase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 23,
                "End": 266
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MTTTTTSTTSSSSSSNSSNSSSSSSSSSNSNSNSSNSSTTTTSTSTSTTTTTTTTTTSTTTTTQQQQQKSNSNSSSNSNSSSSSSSSSSSSSSSSKKEEEKEKEKEKEEEEEKEEEEEEEEEEEEEEKEEKEKEEKKKQQKQQQQQEKQQQQEEEKQQKQQEEEKQKKQQQQQEKQQQQQQQKQQQEQEKEKQQQEQEKEKQQKQQQKQQEKKEEKQQK",
        "response#2": "MTTRRRPPALPRPAAPGSRRPGGPTGPGQAGRPGTADRAGPAGRAAGPGAGPAAPRPARRGAAGPAGTRRPRTRPRAGRAGPGPGPRAGPGRPTGPRTRAGPGRRAGTGPGRPGPGPGAAGPGPGPTTGPGRPTGPGTRTGPGRRGAGRPGPGRTRAAGRRPGPAAAAGPAGRAAGPGGRTAARPGPGPGPAGPGAAGTGRRARAAAAPDRPARPAAGPAGRRAAGPAAAARPARPAPGPAARPRPGTPAGPAAARRATGTAAARTARRGARRAPGPDRGARRRVPRRTV",
        "response#3": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQELPESDRISPVGGLWVEVADTNESKELLKFCRKFTVPLRAALRDAGVLTENPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKYRPTSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEYGKAQIQAKQLYHDREEVTVHVRRI"
    },
    {
        "reference": "MQAIISTAPGQAALVHDRPLPTIRDGYLLVKTKAVALNPTDWKHIEVTQKPGILFGCDYAGIVEQVGPGVQSGFQPGDRVAGFVHGGNSKEPQDGAFAEYIVAKADLQIHIPEHMSFEEAATLGVGITAVGQGLYQTLSLPFPSPSSIHEDGAEKPANPATQPILIYGASTASGVLGIQFAKLSGFAPLAVCSPDHFDLAERLGAVAVFDYADGEDAVEEIQDYVRGMGQPLLKAWDTISIPSSARFCGDALSSGNGPQYASLLSMTCPRPDVTSTTTMAYTVFGEDWGMGTAHFPASGVDAELGRRWWALVQQLLNEGRIQTHRIIAGEGGLDGVLGGLQQLRDSQVRGGKLVFRV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the nucleotide binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding "
            },
            {
                "GO-ID": "GO:0016651",
                "GO-Name": " oxidoreductase activity, acting on NAD(P)H "
            }
        ],
        "go_f_mapped": [
            61,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 115,
                "End": 322
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 355
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 25,
                "End": 113
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 115,
                "End": 322
            },
            {
                "InterPro-ID": "IPR047122",
                "InterPro-Name": "Trans-enoyl_RdTase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 357
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 135
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MKKVLITGGLGFIGSHTAEKLLEKGYEVTILDNFSKTRSKEEKEKILEKFKKNEKLKIVEGDIRDKKSLEEAVKDNDYVLHLAAYVGGEDIEDVNVKGTENVLEACRKNDKVKRIILSSSSAVYGENKKMPYKEEDETNPLNVYGESKLKGEEQVKKYAKEYDLNAIILRYFNVYGPRQRKGVIFDFTKTALEGKKLTIFGDGEQTRDFIYVDDVVNANILALEKGEKNEAYNIGTGKEVSIKELAEKIKEISEKDIEIEFKEPRKYDDKRYYANTEKIKKLGWEPKTDLEEGLKKTFESIK",
        "response#2": "MDISLKDKVAIITGASSGIGEACAKLFAEEGAKGIVLAARRADRLEAVKQECEAKGAKVLVVPADVSKPEDVKAMVDKTIETFGRIDVLVNNAGIGLVGTVETMSEEDWDKVIDVNLKGVFLCTKAVLPHMRERSDGSIVNIASIAGKVGVKRGAPYNASKHGVVGFTDSLRHEMAEYGYGIRCNALCPGYIDTEMFQVGRANMPEEDRKDVVDPV",
        "response#3": "MDRLKDKVAIITGASSGIGKATAILFAKNGAKVVLTARREDKLKEVAEEIKKLEVKVTVVKEKLAESLKSKGELVAREVEKEGAEVLSVPADVSKREDVKNMVKKTMEKFGKIDILVNNAGIALSKPVLEMSEEDWDKVIDINLKGVFLCSQEVAKHMVKQGSGSIVNIASIAGLVGVAGQANYAASKHGVIGLTKSLAAEMAPKIRVNAVAPGYIETEMTAIAKEKMSEEQYKRVVDRIPLKRWGKPEEVANAILFLASDESSYVTGVVLPVDGGYTAR"
    },
    {
        "reference": "MNSKFVLIVVFLAVVSICFANEVWDPEKCGCPPFDKVENAVCTKDRATYDNRCQFDCHAKFLSKSGKTLEESPCIESADPK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Kazal_dom that are essential for its biological function; 2. The protein should be classified within Kazal_dom_sf sharing conserved structural features; 3. The protein must be able to perform the toxin activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0090729",
                "GO-Name": "toxin activity "
            }
        ],
        "go_f_mapped": [
            7
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 74
            },
            {
                "InterPro-ID": "IPR036058",
                "InterPro-Name": "Kazal_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 76
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002350",
                "InterPro-Name": "Kazal_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 74
            },
            {
                "InterPro-ID": "IPR036058",
                "InterPro-Name": "Kazal_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 76
            }
        ],
        "ipr_mapped": [
            376,
            377
        ],
        "response#1": "MKLLLLTGLLLGFYSLSKAECGKKGTCTSGSKCTYCRCPKTGYCSCSRVCSKGSCTCTKGKCGKGETCCDCSNGACDDPSCGKAECGKKGTCTSGSKCTYCRCPKTGYCSCSRVCSKGSCTCTKGKGETCCDCSNGACDDPSCGKAECGKKGTCTSGSKCTYCRCPKTGYCSCSRVCSKGSCTCTKGKCGKGETCCDCSNGACDDPSCGK",
        "response#2": "MKLLPLFFLVLIIARSECDNDTCTCKCEDDTCTCTCSDEEDKCTCNKKDKDCTCTCTDGEEKCTCNKKDKDCTCTCTDGDKETCTCEDDTCTCTCEDDTCTCTCSDEEDKCTCNKKDKDCTCSCTDGDKETCSCGEEDYENKCREINECGCPDDCTCDCENNNCTCKENCKDCSCTAKEGEEKCTCTDNNNCECTCTDKETCTCGEEDYENKCREINECGCPDDCTCDCENNNCTCKENCKDCSCTAKEGEEETCTCTCEDNNCECTCKYGKRLKKAAKRLGKRLKKSGKNLGKRMKKAGKNLKKKYSNL",
        "response#3": "MKSLILLLPVCAILISVSEINVCCADVDDDSCNYKCDGRNCPCCGFARKCCSKSCECTEKDANGNKKIVRRCTREKCPRKHECAGKNMCCADVCCADVDGDSCNYKCDGRNCPCCGGFARKCCSKSCECTEKDANGNKKIVRRCTREKCPRKHECAGKNMCCADVDGDSCNYKCDGRNCPCCGGFARKCCSKSCECTEKDANGNKKKIVRRCTREKCPRKHECAGKNMCCADV"
    },
    {
        "reference": "MKADVFDPRALREAFGAFPTAVTVITASDPAGRPVGFTANSFTSVSLDPPLLLVCVAKTARDYSTMTAAEHFAINILSEAQKDVSIKFARPLEDRFAAVDWARAPNGCPIFAQVAAWFECSMHDVIEAGDHVMMVGRVTAFKSSGLNGLGYARGGYFAPSVAAKANSSAAGGEIGAVAVLERHAALFPLGDQNLSLPRYSAAGGDPAKTLASQLERSGLSVHDWLSLLDL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Split_barrel_FMN-bd sharing conserved structural features; 2. The protein must be able to perform the FMN binding,oxidoreductase activity, acting on the CH-NH group of donors required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0010181",
                "GO-Name": "FMN binding"
            },
            {
                "GO-ID": "GO:0016645",
                "GO-Name": "oxidoreductase activity, acting on the CH-NH group of donors"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0010181",
                "GO-Name": "FMN binding "
            },
            {
                "GO-ID": "GO:0042602",
                "GO-Name": " riboflavin reductase (NADPH) activity "
            }
        ],
        "go_f_mapped": [
            59,
            253
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR012349",
                "InterPro-Name": "Split_barrel_FMN-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 161
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050268",
                "InterPro-Name": "NADH-dep_flavin_reductase",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 161
            },
            {
                "InterPro-ID": "IPR012349",
                "InterPro-Name": "Split_barrel_FMN-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 161
            },
            {
                "InterPro-ID": "IPR002563",
                "InterPro-Name": "Flavin_Rdtase-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 158
            },
            {
                "InterPro-ID": "IPR002563",
                "InterPro-Name": "Flavin_Rdtase-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 16,
                "End": 157
            }
        ],
        "ipr_mapped": [
            858
        ],
        "response#1": "MTEPHRAVPPAVTAALAAAVADGAGARRLTALLADRPPPPPGATAVTTDPRAADALAAAGLPVRPLTADRDAAGADAAADLLRDGLPAALAVVTAADGPRGWRDRRGAAVLRASWDHPPPPDHPDPAPADPVWDALDRWLADATAAGEPEPYAIALATTDRHGRPATRTVRVLRRDGDRLYFATDLDSRKARDIRTDPRAAACVWRPGWRQATLTGTVTPAPAPPTPPPPPPPPEPPTGPHRHPPHRHRHLPQHRRRRRRRRRRRPPRPRHRRPPPPAAAAATAPTRPAATATAPPPAARPAHPAAIPPPAARPTHPTAPPPPRHRRPRHPRPPPRPAPRARRPPRRPRP",
        "response#2": "MARPRRSGARPAAGRASEGARARAHARAARPAAAVPRCRAAPLARAPPRRAARRAAPAAAAAPARACRRSARARASGRTAPAGRRAAPRARRAAPPRRAARRARRAAARRAAARRAAAAAAAAHRAARRAARRAPRRAVARRARSCASTCSSTSKMSDDPLAQFKRWFDEAVAANVKDPNAMALATVDEHGRPSVRMVLLKGYDERGFVFYTNYESRKGRELAANPNAALLFYWLPLERQVRVEGRVERVSEEESDAYYASRPLGSRIGAWASKQSAVIESRAVLEAKFAELKAKYPVGEVPRPPHWGGYRVVPDVIEFWQGREHRLHDRLVYRRADSGQG",
        "response#3": "MAHARRRPPRAARRAARHPARPVPRRRRHARHRRRGAPRARPRRHARPRHRTRARRPARPARRATRRPARRATRRPPGAAPPAPAARRPARRAPPGRPATAPPRRPAAPTAPPPRRRTATAPRPRAPAPPPAARARRTTPPAAPRTTPPRSTPRSAPRAAPRARPAARARRRRGARAAPRRTAPRRAPRLAPARARRTRTAPRPAPRPAPAGRTAPGTTSSTSTTSTTSTTSATSATTAGTSTGTSTSSTSTTTTATSATTSATSATTTTATTSSSAPPAPSSVPPAPSSSAPPAPSAPPAPSSAPARAAAVAGTARRRTAGAAPAPAPAPAPGPAPGALPA"
    },
    {
        "reference": "MWPPVDVRSLTAESLGRASLILAVDLLLFVTSILNITVIAFTPDLSDVIGCYLISLSVADLLTAIFVIPLSIYSTLEGNWRIGGDNSIICKSAAYLQIALFCSTVYTFAWICIDRYSAMMKPSRYSEQSLTRCKCWIVFSWLTSMLLCCPIIVARMQVVFYPDAQLCVLDWSATSAYSVTLLLLVFVPTLVTVFNTGWKIWSAMRNPAALDDSQRMLVETDPNFVLTGFLFVTFFLSWLPLITLKVCELIWGPFDMDLSMLTFFFVWLAVSGPCCKFLIYMFTNHQFRRSFLSYISCSMCCSSRSRYEYHDIGNNSFL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            }
        ],
        "go_f_mapped": [
            0
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 223,
                "End": 247
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 262,
                "End": 288
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 49,
                "End": 70
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 132,
                "End": 153
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 97,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 275
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 31,
                "End": 280
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 223,
                "End": 247
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 262,
                "End": 288
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 49,
                "End": 70
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 132,
                "End": 153
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 97,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 275
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 31,
                "End": 280
            }
        ],
        "ipr_mapped": [
            0,
            1
        ],
        "response#1": "MWLFLFLPKEHLILIIVKFLLHCFFFILFTLLIFSINTMHLMEGNHTSVTEFILLGLTDDPELQKILYGLFLSMYIVTMLGNLLIILATRSDSHLHTPMYFFLSNLSFVDACYSSTTVPKMLVNFNSENKTISYLGCATQMFFFLALASTECFLLAVMAYDRYVAICNPLLYTVKMSPQVCVLLVAASWVGGSFNALIHTLMTFRLSFCGSNVINHFFCDVPPLLKLACSDTHVNELLLFSGVNLIVTTLIILISYVYIISTILKIRSTEGRHKAFSTCASHLTAVSLFYGTIIFMYVRPKSNYSTDKDKVVSVFYTVVTPMLNPLIYSLRNKDVKGALKKLLGRKIFSS",
        "response#2": "MSGGNHTAVTEFILLGLSDRPELQVILFGLFLSMYTVTVLGNLLIILATRVDSHLHTPMYFFLSNLSFLDICYSSVTVPKMLVNFLSEKKTISYLGCATQLFFFLAFGGTECFMLAVMAYDRYVAICNPLLYTVSMSKQVCVLLVAGSWVGGSINAMIHTIMTFSLTFCGSNVVNHFFCDIPPLLKLSCSDTYVNELVLFVMCGSVTMSSFLIILISYVFIVSTILKIHSTEGRHKAFSTCASHLTAVTLFYGTITFMYVLPKSYRTPDQDKVVSVFYTVVTPMLNPFIYSLRNQDVKGALKRLLGRKVFSANLRQ",
        "response#3": "MEEEEDMNQWLLSMENRTEENNTTETEEEFTLGEKIVVAVVIIVMIVVTVLGNLLTILAIRISSKLRMTVSNMFITSLALADFLLSVVVMPFSAVSEVMGNNWIFGNVGCKMYMFLDVLFATASILNLTSISIDRYYAITHPLSYPVKMTSKLAVGLVVYSWIHSASVSLPPLFGWGSYDYQKGKFSCLPIWSDEEDKTTSSLSYIISSSLASFYIPCIVMVICYLNIFLTARRKAKEIHEAAIAMSSNQNNSNASSSSNSSSTTVSTSSQSSSTNSTNKQQDTSSRSQSTGKRRFVHSSSSSSERKAAKTIGAILGAFIVCWAPFFTVNTVEALCQGCVSETMMSFVMWLGYVNSMLNPFIYTLMNRDFKNAFKKLLTCRC"
    },
    {
        "reference": "MKDLFEHIYANKGSIGRWSDHAEGYYVFPKLEGELGPHMKFQGKEILNWSINDYLGLANHPEVRKVDAEAAAEYGAAYPMGARMMSGHTTMHEELEKRLAKFVHKEASYLLNFGYQGMVSIIDALVTKNDVIVYDVDAHACIIDGVRLHFGKRYTYQHNDMESFEKNLERAAKLAETTGGGILVISEGVFGMRGEQGKLKEIVALKKKYPFRLLVDDAHGFGTLGPRGEGTGVHQGVQDEIDVYFSTFAKSMAGIGAFVAGNAKVVDYLKYNLRSQMFAKSLPMIYVKGALKRLEMMETMPELQQKLWDNVNRLQNGLKERGFNIGNTNTCVTPVFLHGSIPEAMAMVNDLREHYGIFLSIVVYPVIPKGMILLRIIPTASHSKEDIDRTLEAFSAIREKLETGVYRAINAELTKEMGDM",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Aminotransferase_I/II_large that are essential for its biological function; 2. The protein should belong to AON_synthase_class-II that shares evolutionary origin and functional similarity; 3. The protein should be classified within PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_small, PyrdxlP-dep_Trfase_major sharing conserved structural features; 4. The protein should include a Aminotrans_II_pyridoxalP_BS that enables ligand binding under diverse conditions; 5. The protein must be able to perform the pyridoxal phosphate binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008890",
                "GO-Name": "glycine C-acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": " pyridoxal phosphate binding "
            }
        ],
        "go_f_mapped": [
            33
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR004839",
                "InterPro-Name": "Aminotransferase_I/II_large",
                "InterPro-Type": "DOMAIN",
                "Beg": 45,
                "End": 394
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 401
            },
            {
                "InterPro-ID": "IPR050087",
                "InterPro-Name": "AON_synthase_class-II",
                "InterPro-Type": "FAMILY",
                "Beg": 44,
                "End": 396
            },
            {
                "InterPro-ID": "IPR001917",
                "InterPro-Name": "Aminotrans_II_pyridoxalP_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 247,
                "End": 256
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 396
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 60,
                "End": 300
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR004839",
                "InterPro-Name": "Aminotransferase_I/II_large",
                "InterPro-Type": "DOMAIN",
                "Beg": 45,
                "End": 394
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 21,
                "End": 401
            },
            {
                "InterPro-ID": "IPR050087",
                "InterPro-Name": "AON_synthase_class-II",
                "InterPro-Type": "FAMILY",
                "Beg": 44,
                "End": 396
            },
            {
                "InterPro-ID": "IPR001917",
                "InterPro-Name": "Aminotrans_II_pyridoxalP_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 247,
                "End": 256
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 41,
                "End": 396
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 60,
                "End": 300
            }
        ],
        "ipr_mapped": [
            197,
            198,
            199,
            73,
            74,
            75
        ],
        "response#1": "MRRRPRRRRSARLRDAPRDARDAARRPPDAPRGAPDAARRPARRPPDALPDARDVAVGLPDALPEARDVAEGLRGALPDARDAAEGLRGALPEARDAAGGLPGALPEARDAARRPPDAPPEARDAARRPARRPDDVPRRAERPERPPDVARRAPEVPDAARRPDDVPRRAPRSERPPDVARRAREAPEDAPPDAVPDAADDPPDVARRAPEAPEDAPPDAAPDAADDAPPDAPPEARDAPPDVPRRLPRAPRRRVEPY",
        "response#2": "GAWIERDGRRLLNLASNDYLALSQHPGVIDAGIEALRRYGAGATGSRLVTGNTPLHAELEAELAALKGAEAALVFSSGYTANLGAVVGLSGPGDVIVSDALNHASIVDACRLSRATVVVTPHRDVDAVDAALRARRPEARRALVVTDTVFSADGDLADLAALHDVCRRHDALLLVDEAHGTGVRGPRGAGLLEELGLAGAPDVVMTGTLSKALGSQGGYVAGSAPVREHLINAARPFIFDTGLPPAAVGAARAALARLPAVAAACDLAGRSSSAVVSVIVGPPEVAVAVAARCLDRGIAVACFRPPTVPAGTSRLRLTLTAAHTPADVDLAVEVLTEVLAEPPARR",
        "response#3": "MINFSSNDYLGLSNNKEIIEEIKKYANYGIGGTGSRLLTGNFKIYEELEEEIAKFKGTESALIVSSGYTANLGAITSLSDKNTLILSDKFSHASIIDGIRLSKAKFLRFKHNDYEHLEKLLKENKDKKNKLIVTESVFMGDITYLKKLVEIKKKYNCMLMVDEAHATGILGENGKGLVEYYNLEKEIDIHTGTFSKALGSFGGYVCCKKEYKEYLINNMRSFIFTTALPPADVAAAKKSIEIIKKEKNKVENLLENSNYIKEKTNLKILDSKSCIICIKLENEEKALEINKKLKEKNIFVSVIRPPTCKNALRITITSEMKKEEIDEFINVLKEFL"
    },
    {
        "reference": "MSDTLASPSPETASGIPDYPMSRSAGCPFAPPPGVMALAAAKPLTRVRIWDGSTPWLITGYEQVRELFSDSRVSVDDRLPGFPHWNAGMLSTVHKRPRSVFTADGEEHTRFRRMLSKPFTFKRVEALRPTIQQITDEHIDAMLAGPQPADLVAKLALPVPSLVISQLLGVPYEDAEMFQHHANVGLARYATGADTVKGAMSLHKYLAELVEAKMANPAEDAVSDLAERVKAGELSVKEAAQLGTGLLIAGHETTANMIGLGVLALLVNPDQAGILRDAQDPKIVANAVEELLRYLSIIQNGQRRVAHEDIHIGGETIRAGEGIIIDLAPANWDAHAFTEPDRLYLHRAGAERNVAFGYGRHQCVGQQLARAELQIVYRTLLQRIPTLTLATALEDVPFKDDRLAYGVYELPVTW",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 414
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 203,
                "End": 383
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 356,
                "End": 365
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 414
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 297
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 249,
                "End": 266
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 103,
                "End": 114
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 297
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 150,
                "End": 166
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 304,
                "End": 331
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 167,
                "End": 182
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 363
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 332,
                "End": 347
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 204,
                "End": 226
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 414
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 203,
                "End": 383
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 356,
                "End": 365
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 414
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 297
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 354,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 249,
                "End": 266
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21
        ],
        "response#1": "MAVNRLTRPLSEETSHALTKEWTDNPEWHEITAKETVLRLVAQLSSRVFLGEELCRNEDWLKITTNYTVDSFKAAEELRLWPEFLRPIVHWFLPSCRNLRAQLAEARKIINPVLEERKREQAAAKENNTKKYNDTIEWFEEVADGRKYDPALAQLSLALAAIHTTTDLLTQTLLDLCSQPEYQELIQPLREEIIRVLNAHGGWKKTALYNLKLMDSALKESQRLKPVNLVSMHRVAMEDVKLSDGTVIPKGTKISVAAHAMWHDEKYYEDADKFDGYRFVRMREDPNSAQLVSTSPEHLGFGHGKHACPGRFFAANEVKIALCHILLKYDIKLVEGAKPKNVNVGFFLLADPTAKLMVRRRV",
        "response#2": "MAASPNISDYVPFLKSLDLQGIRKKMKASFEKLHGIFDNVITERIKSTKDSNNNYYEEKKSKDLLDVLLSYLDNNNDSALTTDNIKALIFDMFVAGTDTSSSTMEWAMAELIRNPRVMEKVQAEVRNVVGKGKVEESDIDNLKYLQMVVKETLRLHPPAPLLLLREAKEDVEVAGGYKVPKGTRVIVNAWAIGRDPKAWEDPECFKPERFENSIDVKGQNFELIPFGAGRRICPGMPLAIRVVHLALASLLHSFDWKTKHEKIDMEEKFGITMQMKYPLTAIPIPRV",
        "response#3": "VRLDLKKARAMIEPVIRERRKTKAEAMANKSDPDYEKPNDMLQWMMDNATPEEQDPEELAHRQLLLSVAAIHTTSDLLTQVMFDLCARPELIQPLREEVIQVIREHGPDGWNKTALYKMKLMDSVIKESQRLKPIAVLGMHRMAVKEGVTLSDGTFIPKGTKISVPAYPMHHDPSIYEDAETFDGYRFVRMREANPEKENAFQFVSTSPEHLGFGHGKHACPGRFFAANEAKIALCHILLKYDFKLAEGQKPKNINNGLFLTADPSAKIMVKRREEI"
    },
    {
        "reference": "MSEKIVVVDDEKEIADLVTTFLQNEGFSVQPFYDGTSAIAYIEKEAIDLAVLDVMLPDIDGFQLLQQIRKTHFFPVLMLTAKGEDLDKITGLSLGADDYVTKPFNPLEVVARVKTQLRRYQRYNHSTASPTVEEYEKDGLILKINSHQCILYGKEVFLTPIEFKILLYLFEHQGSVVSSETLFEAVWKEKYLDNNNTVMAHIARLREKLHEEPRKPKLIKTVWGVGYIIEK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Sig_transdc_resp-reg_receiver, Sig_transdc_resp-reg_receiver, Sig_transdc_resp-reg_receiver that are essential for its biological function; 2. The protein should be classified within CheY-like_superfamily sharing conserved structural features; 3. The protein must be able to perform the phosphorelay response regulator activity,transcription cis-regulatory region binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000156",
                "GO-Name": "phosphorelay response regulator activity"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000156",
                "GO-Name": "phosphorelay response regulator activity "
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": " transcription cis-regulatory region binding "
            }
        ],
        "go_f_mapped": [
            88,
            91
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 117
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 3,
                "End": 113
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 113
            },
            {
                "InterPro-ID": "IPR011006",
                "InterPro-Name": "CheY-like_superfamily",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 126
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 117
            },
            {
                "InterPro-ID": "IPR001867",
                "InterPro-Name": "OmpR/PhoB-type_DNA-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 132,
                "End": 231
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 3,
                "End": 113
            },
            {
                "InterPro-ID": "IPR016032",
                "InterPro-Name": "Sig_transdc_resp-reg_C-effctor",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 134,
                "End": 229
            },
            {
                "InterPro-ID": "IPR001867",
                "InterPro-Name": "OmpR/PhoB-type_DNA-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 153,
                "End": 228
            },
            {
                "InterPro-ID": "IPR001867",
                "InterPro-Name": "OmpR/PhoB-type_DNA-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 140,
                "End": 229
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 113
            },
            {
                "InterPro-ID": "IPR011006",
                "InterPro-Name": "CheY-like_superfamily",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 126
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 125,
                "End": 231
            },
            {
                "InterPro-ID": "IPR039420",
                "InterPro-Name": "WalR-like",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 227
            },
            {
                "InterPro-ID": "IPR001867",
                "InterPro-Name": "OmpR/PhoB-type_DNA-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 153,
                "End": 229
            }
        ],
        "ipr_mapped": [
            225,
            223
        ],
        "response#1": "MNAARTPTPARVLVVDDSAVVREVLVRALEADPALRVVGTARDALEARDLIKALNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVLIVSSHTQGRNAELTFRALELGAVDVVTKPAVGDAATFGALLAEKVRAAARARLAPAPSPRPRAAPPRLTAIGASAGGPAALVELLRALPAAFPAPLVIVQHVDQAFAAGIAAWLDAATALPVRIAAEGDAPLPGRAVLAPTGHHLELRGGALRYTAAPPRSPYRPSVDVFFASVARAYGAGAVGVLLTGMGRDGREGLRAMRDAGARTVAQDEASSAVYGMPRAAAEAGLADRTLPLPRIAEELAR",
        "response#2": "MTAPAAAAAAAAARRRRRRRRRRRRRRRRRRRPPPPPPPRRRRRPPPPPPPPPRRRRRPPPPPPPPPPRRRRRRRRRRRPPPPPPPPPPSSSSSSSSSSSSSSAAAAAAARRRRRRRPPPPPPRRRRRRPPPPPPPPSSSSSSSSSSSSSSSSSSSSSSSSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAAAAAADDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD",
        "response#3": "MSKIRVLCVDDSALMRQIMTEIINSQSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLSIKDSIIILAEKIRAASRAKLNHSPLLSSEKLIIIGASTGGTEAIREVLQPLPLSSPALLITQHMPPGFTRSFAERLNKLCQISVKEAEDGERVLPGHAYIAPGDFHMELARAGNYIIKLNQGPPVNRHRPSVDVLFRSAAKHAGRNAVGVILTGMGNDGAAGLLEMRQAGAWTLAQDEASCVVFGMPREAINMGGASEVVPLSQISQRILTHIAAGRA"
    },
    {
        "reference": "MASRGVNKVILVGNLGQDPEVRYMPSGGAVANFTLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDQSGQDKYTTEVVVNVGGTMQMLGGRQGGGAPAGGGQQQGGWGQPQQPQGGNQFSGGAQSRPQQQAPAAPSNEPPMDFDDDIPF",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Primosome_PriB/ssb, ssDNA-bd, ssDNA-bd, Primosome_PriB/ssb, ssDNA-bd, ssDNA-bd, Primosome_PriB/ssb that shares evolutionary origin and functional similarity; 2. The protein should be classified within NA-bd_OB-fold, NA-bd_OB-fold sharing conserved structural features; 3. The protein must be able to perform the single-stranded DNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003697",
                "GO-Name": "single-stranded DNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003697",
                "GO-Name": "single-stranded DNA binding "
            }
        ],
        "go_f_mapped": [
            83
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 111
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 117
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 146
            },
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 105
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 174
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 143
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 174
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 157
            },
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 112
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 111
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 117
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 146
            },
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 105
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 174
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 143
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 174
            },
            {
                "InterPro-ID": "IPR011344",
                "InterPro-Name": "ssDNA-bd",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 157
            },
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 112
            }
        ],
        "ipr_mapped": [
            204,
            732,
            733
        ],
        "response#1": "MARGINNVVLVGRLTKDPELRYTPNQVAVATFTLAVNRTFKNQQTGEREADFINCVIWRQQAENVANFLKKGALAGVTGRIQTRNYENQQGQRVYVTEVVADSVQFLESRATREGGSYGGNNGGFGGNNSGGFGNNSGGGFNNNSNNFGNNGGNNNGGFGNNGGNNGGFGNNGGGFDNNSGGFGNNGGGFDNDSGGFGNNGGNNGFGGFGGSGNSAPKNDSPFGSGNPMDISDDDLPF",
        "response#2": "MARGVNTVTVVGNLTADPELRYTPSGAAVANFTLASTPRFFDRQSNEWKDGEALFLRCNIWREAAENVAESLTRGARVIVSGRLKQRNFEAQSGERRTVIEVEVEEVGPSLRYATAKVNKASRGGGGGGGGQSGGGGQSGGGGGQSGGGGGGQSGGGGPSGGGGGGGGGGGGGRGVNTVTVVGNLTADPELRYTPSGAAVANFTVASTPRFKDRSGEWKDGEALFLRCNIWREAAENVAESLTRGARVIVSGRLKQRNFEAQSGERRTVIEVEVEEVGPSLRYATAKVNKASRGGGGGGGGQSSSGGSSGGGGGGGGGGGPMDISDDEPPF",
        "response#3": "MASVNKVILVGNLGQDPEVRYMPNGGAVANISLATSETWKDGNGQTQEKTEWHRIVLFGKLAEVAGEYLRKGSQVYIEGSLQTRKWQDQSGVDRYTTEIVVNVGGTMQMLGGRQQGGQQPAMNQNQGNQGNQNQNQNQNQGNQGNQNQGNQGNQNQNQGNQGNQNQNQGNQNQNQNQGNQNQGNQGNQNQNQGNQNQNQNQNQNQGNQNQGNQGNQNQNQGHNQGGGFGDDSPFGNSNPMDISDDDLPF"
    },
    {
        "reference": "MLKFLSTKCKQFNSLNHIIKHKIYFPSKSNKSYFSSSVKDVEKKNKEPIIQLTNDAINKMKEINLKYKNSKALKVCVEAGGCSGFQYSFSLIDKNKIKDKEQIVYDKDCIVVIDKQVIDILKNSKIHYINNLISKKFTIENIQNISSKCSCGNSFDIDFV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FeS_biogenesis that are essential for its biological function; 2. The protein should belong to FeS_cluster_insertion that shares evolutionary origin and functional similarity; 3. The protein should be classified within HesB-like_dom_sf, HesB-like_dom_sf sharing conserved structural features; 4. The protein must be able to perform the 2 iron, 2 sulfur cluster binding,4 iron, 4 sulfur cluster binding,iron ion binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051537",
                "GO-Name": "2 iron, 2 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0051539",
                "GO-Name": "4 iron, 4 sulfur cluster binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051537",
                "GO-Name": "2 iron, 2 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0051539",
                "GO-Name": " 4 iron, 4 sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            }
        ],
        "go_f_mapped": [
            78,
            79,
            13
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 141
            },
            {
                "InterPro-ID": "IPR000361",
                "InterPro-Name": "FeS_biogenesis",
                "InterPro-Type": "DOMAIN",
                "Beg": 50,
                "End": 153
            },
            {
                "InterPro-ID": "IPR016092",
                "InterPro-Name": "FeS_cluster_insertion",
                "InterPro-Type": "FAMILY",
                "Beg": 50,
                "End": 156
            },
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 49,
                "End": 160
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 141
            },
            {
                "InterPro-ID": "IPR000361",
                "InterPro-Name": "FeS_biogenesis",
                "InterPro-Type": "DOMAIN",
                "Beg": 50,
                "End": 153
            },
            {
                "InterPro-ID": "IPR016092",
                "InterPro-Name": "FeS_cluster_insertion",
                "InterPro-Type": "FAMILY",
                "Beg": 50,
                "End": 156
            },
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 49,
                "End": 160
            }
        ],
        "ipr_mapped": [
            368,
            369,
            372
        ],
        "response#1": "MAPIEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFLSSEQVSLPRLMPPSDPLRFLLLLPASPSPSHPPHHERLQEPPTPPPPPPQEPHRIPPPPAPHQVERPHLLRRRPLPPLATAASRLLSPAPRLLAPPPPRQLPPTSSLLASRSSLLSRSLPRSLPSEPTYDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI",
        "response#2": "MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSITVLYTGEDLLIPKSIDTLDEYLSIDLADLKVPGFCVAGDVILKKGFVLGKGDHVSVSCPYRLTISEDTIITCTYDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI",
        "response#3": "PPPPPSPPSPSPSPSPSPPPSPSPSPPPLLPPPHAPPPSPAAAAPAPHPDVALPLEFSDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSFSCVGGGGPGGGGGRGARVRGGAAAAAPPPPPPSPAAAAGGGRGGGGGGAGSPAPRRVHPPPLRRSPAAPIPPPPHPPPGAPPPPPPRTRRPPPPPHPPPPPPPPPRRPTPASMALPLEFSDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI"
    },
    {
        "reference": "MTAATLFESTDGTVVLLDLPRSIEDAQQHPAAVTLPEAPSLVTNSCRDGTSWTRRLISSPPPETPFVTPEPKNGPSPLPAAAQVAQLMIQASVTGALEELRTNYSGPYLLPRQLSPQRMIADGGKAVDDYKSPHACDLESCSTTAEDATKGRYYFPPESHHVLGTIQETKTLLLQSAPNFNVIVLDPPWPNRSAKRKKGGYKVATTTDDIRALLSDVPIPSLLARDGLVAIWVTNKPAFLDMLTSPRDGILSEWGLELVGEWSWLKITTSAEPILPIDSAHRKPWEPLLIAQRKGSKRVFPPFWRRRVIVSVPDTHSRKPNIRDLVNPMLPPRSRGLEIFARNLTAGWWAWGDDVLHFQERSNWVMAESKSPATGC",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein should contain DNA_methylase_N6_adenine_CS that is preserved across related proteins; 3. The protein must be able to perform the methyltransferase activity,nucleic acid binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0003676",
                "GO-Name": "nucleic acid binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity "
            },
            {
                "GO-ID": "GO:0003676",
                "GO-Name": " nucleic acid binding "
            }
        ],
        "go_f_mapped": [
            20,
            116
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002052",
                "InterPro-Name": "DNA_methylase_N6_adenine_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 183,
                "End": 189
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 179,
                "End": 306
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002052",
                "InterPro-Name": "DNA_methylase_N6_adenine_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 183,
                "End": 189
            },
            {
                "InterPro-ID": "IPR007757",
                "InterPro-Name": "MT-A70-like",
                "InterPro-Type": "FAMILY",
                "Beg": 180,
                "End": 353
            },
            {
                "InterPro-ID": "IPR007757",
                "InterPro-Name": "MT-A70-like",
                "InterPro-Type": "FAMILY",
                "Beg": 139,
                "End": 374
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 179,
                "End": 306
            }
        ],
        "ipr_mapped": [
            964,
            70
        ],
        "response#1": "MAFSPASEVLLRNTDEFAGKRVLVINDTDDLTRALRRVAEHVTSVQQYYPHSLQLEREGFTVVLSEPEGPFDVALYRVPKAKPELTEQLLRVSQLLVPGARVIAVGENRSGVNSAEKVLAQYGLPTTTTLAWKRARLIHAVRAEQPAPNPYETTYKLPDSPWTVTSLPGVFSRTGLDVGSRVLLDALPTDVRGRILDLGCGAGVLSAVVAQRSPQARLTLVDVSAPAVEAARATLAANGLTGEVYASSVLSDVKGRFDTIISNPPFHQGFETSLHAAQQLLVDARRCLVIGGELRVVANRHLPYPDVLDETFGNHTVVAANPKFVVYSSVKTAPPRR",
        "response#2": "MTQPYTYTVAGRTLTVEALPGVFCADGLDVGTRVLLDALPRDVRGRVADLGCGAGVVATTVALSNPQVRVTLVDVSPVAVECARRTLAANDLADRAEVVEGDGLAAVTGVFDTVLSNPPFHSGVRADAYRLLTDARRCLVPGGRLIIVTRRDAGYRRRLADVFGPVDLIADNGRFVVLAAQQPQQQPQQQPQQQPPQQPPQQPPQQPPQQPPQQPPQQPPQQPPQQQPPQQPPQQPPPQPQAQPQPQQPQPQPQQPQPQPQPQQPQPQPQPQPQPQPPQPQPQPQPQPQHQPQQGPRRRR",
        "response#3": "MSSAAPAAPQAAARTYEVELAGHTLRVTSLPGVFSAARLDVGTEVLLRSLPDVRGRRVLDLGCGSGVLAVAAALRGAASVTAVDVSAPAVAAARESARRNGLADRVTVRLNGVSEVRGRFDMVLSNPPFAARLLPELLEHAPELLVPGGELVAVGLRREGVRSTDELLDRYCGPTTTVAAAKKHRVISAVPGEPGAHQPAGPYQTTYRLPDSDWTITTTAGVFSRSGLDVGARVLIDALPANVRGRVLDLGCGNGVLGVVAAQRGAASVVFVDESAPAVASARETLRANGLDDRGEFRVSSVLSGVRGRFDLVLSNPPFHDGIATSTYAAQELLVDARRCLVIGGELRVVANRHLAYPHVLDEVFGNCETVAANGKFVVYSAVKTARAPRNGDDD"
    },
    {
        "reference": "MFNNFLNMYMCTLAEKLCKFKKNNFNNIHRNNNFYRDNNFYRDNNFYRDNNFYRDNNFYRDNNLYTNNNLYRDNNFYRDNNFYRDNNFYRDNNLYTNNNLYRDNNLYTNNNLYRDNNFYNITLRKFHFIQTISNNNFNFEIIKKYGDVINKIMFIHTQKKNKQERFMFNNKKYIKRKEYILNDLNEFISIIPHPEINNEITNNSNQKKNKDNKQNVLSTNQQIITNYNLNHKENVTSNLNFNNKEEDEKKLDKLLKKRNIKKRDIVTITEEAKEELKKIISINKKENNNNYNNMNTICSDNHNDMNTICNDKNILKLFFITKGCNGLTHSFNFISKKDIHKEDEIIYDDQNNILLVIDKNCILYVINTTLDYYKDDLTEKFIFKNPNITSICPCGTSFHFSKKK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FeS_biogenesis that are essential for its biological function; 2. The protein should belong to FeS_cluster_insertion that shares evolutionary origin and functional similarity; 3. The protein should be classified within HesB-like_dom_sf, HesB-like_dom_sf sharing conserved structural features; 4. The protein should contain FeS_cluster_insertion_CS that is preserved across related proteins; 5. The protein must be able to perform the 2 iron, 2 sulfur cluster binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051537",
                "GO-Name": "2 iron, 2 sulfur cluster binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051537",
                "GO-Name": "2 iron, 2 sulfur cluster binding "
            }
        ],
        "go_f_mapped": [
            78
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 265,
                "End": 400
            },
            {
                "InterPro-ID": "IPR000361",
                "InterPro-Name": "FeS_biogenesis",
                "InterPro-Type": "DOMAIN",
                "Beg": 310,
                "End": 395
            },
            {
                "InterPro-ID": "IPR017870",
                "InterPro-Name": "FeS_cluster_insertion_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 381,
                "End": 398
            },
            {
                "InterPro-ID": "IPR016092",
                "InterPro-Name": "FeS_cluster_insertion",
                "InterPro-Type": "FAMILY",
                "Beg": 310,
                "End": 399
            },
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 263,
                "End": 386
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 265,
                "End": 400
            },
            {
                "InterPro-ID": "IPR000361",
                "InterPro-Name": "FeS_biogenesis",
                "InterPro-Type": "DOMAIN",
                "Beg": 310,
                "End": 395
            },
            {
                "InterPro-ID": "IPR050322",
                "InterPro-Name": "Fe-S_cluster_asmbl/transfer",
                "InterPro-Type": "FAMILY",
                "Beg": 256,
                "End": 399
            },
            {
                "InterPro-ID": "IPR017870",
                "InterPro-Name": "FeS_cluster_insertion_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 381,
                "End": 398
            },
            {
                "InterPro-ID": "IPR016092",
                "InterPro-Name": "FeS_cluster_insertion",
                "InterPro-Type": "FAMILY",
                "Beg": 310,
                "End": 399
            },
            {
                "InterPro-ID": "IPR035903",
                "InterPro-Name": "HesB-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 263,
                "End": 386
            }
        ],
        "ipr_mapped": [
            368,
            369,
            370,
            372
        ],
        "response#1": "MAALRLLLRPRLRLGARGRLPANPARLRRLHSVPRPPPPPPPPPPPPPPPPRPPPPPPPPRLLLPPLRPRPLLLLPLPLPLPLLPPPRRRAESDDYDDVGLPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI",
        "response#2": "MDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSVSQAAPAPRPPPSPGPRPRPPLPRPRLPRPRSRPRLPRPPPRPPPPPRARLRPPRPLRARARALRARAPRARARARLRPPPPPPPRALARPPPPRARPPRLRPPAPPPPPPPPAPPAPPASLRPPLPPRPRDAYDDVALPIEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI",
        "response#3": "MSDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSITVSEAAAGLPLSALVERGALALGGWRGRRCPPPPLEDGLRAPPLPSPLPPRPPRPPPLSGGREGRKPGPEPPPLPPPPPWGRGRAMSDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI"
    },
    {
        "reference": "MLFQDLSFPAAIGAVFGAVAISVAARCIYDLFFHPLRNFPGPKRAAIWSFYEFYYDVIRDGTYLWEIEKMHQKYGPIVRINSRSLHIHDPEYFNTIYAGSGRKVNKELSAVSGYTFPHSTISTLDHDLHRKRRAIVSPYFSKRAIAEIEPVIHERLNVLISRLAEAKGSIVDLTSAFSAYTADVVTYHFYGTHANYIGSKDFKYGLKDALTVLLNLYNLTRFLPVPANTLKNLPLPILGLINPNFPLVVSAREANKKMVLGYLNKPDEDKKAMKDARSKSVIVSALTDPNVPDAEKTLDRLLDEGETIIFAGIDTTARTLGVALFHLLNNKDVLMKLRKELQAVAKPDGQQWTTTELEAVPYMRGVVQEAIRLAYGLVVRIPRISPHEALRYNGFVIPPGTPVSQSTYLVNNDPSVFPNPQVFDPERWVKAAQDGVSLDKYMVSFSKGSRGCLGINLAYAKLYLGIARVATSLDMELFETTAKAISVYHTRGFAFPKEGDGAVKARVMGLCK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cytochrome_P450_monoxygenase, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 499
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 382
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 452
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 300,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 406,
                "End": 430
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 475
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 476
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 489
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 328
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 463
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 443,
                "End": 452
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 365,
                "End": 376
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 445,
                "End": 454
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 495
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 499
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 382
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 452
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 300,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 406,
                "End": 430
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 475
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 476
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 489
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 328
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 463
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 443,
                "End": 452
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 365,
                "End": 376
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 445,
                "End": 454
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 495
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21,
            31
        ],
        "response#1": "MAANASTLIVAGSETTATLLSGTTYYLLRNPRVLEKVQAEVRSTFRSEDEIRHGQKLNELRYLHAVIEEGLRMYPPVPGNLPRVVPRGGATIDGQWVPEGTVVSVPQYAAYHSEKNFTDPYSFKPERWLGEGAKDRREAFQPFSLGPRNCIGKNLAYHEMRLILARLLWNFDLELCDESGNWLEHQKAYVLWDKPPLMVRLKRVTRD",
        "response#2": "TFEDLQANASVLIIAGSETTATALSGTTYYLLTNPDKLQKARDEVRNAITTAGCRDQRITFTEVQKLRYLHAVLEEAMRLYPPVPMGLPRVVPRGAMIAGKWLPEGTTVSVNQFAAYHSDRNFKDAFSFRPERWVDELPSEFEDDRRDALQPFSLGPRNCIGKNLAYHEMRLTLARMLWNFDLELVEGAKWEEQKHYVLWDKMPLMVRLV",
        "response#3": "MSPNSGPRGRGSKSRGDFLDAMLSSNDEETGMTFEEIHANANLLIIAGSETTATLLSGATYFLLKNPRVFEKVRDEVRSTFNSEDEIDIGSKISSLRYLHAVLEEALRLYPPVPIGLPRATPEGATIDGQYIPGGTVVSVHQYAAYHSARNFKEPDKFLPERWLDDHPEFKNDKRDALQPFSYGPRNCIGKNLAYHEMRLTLAKLLWHFDLELCPESKDWTNQKAYLLWDKLPLMVRLTPVR"
    },
    {
        "reference": "MGASTFSQSFAEGYAAWALMLPALVGCALLIYRAFFAIRYPANLPLAGEPDGKRTFSWRTRWRYYIDCEALYKETYDNYTKHGKTVLLPGLGFRHDIVLPQSAMRDIMARPEKELSHADAVLELVQLKYSLGHEKYKADPWPCMLVKSDINSKLEAVCDGMNEELKYAFDKYVGCDTESWKEVDLLETIRMIIMAAASRFTVGFPLCRSEAYLRACWKVNDGIMMNGGLTGATPRLLRPIVGPLVTMKLRQSIEQVKKHVEPIYRQRVQALSQQNSAEKPASDETQDLFQQMLRYAQRERPGELHDLPSMCRRLCFANFAAVHQTTLLVTNMVLNIVSSDPQHNTISVLRDEVKDVIGPDSNAKWTKYKVAQMIKSDSVARETMRLYSNTNRGVFRKVLVEGIKTEDGIELPKGAYVSFLGRPLQCDPETFEDPFEYNPFRFSRIREQAPRDTKGRSSASHLSFVSTSPEHLPFGHGGHSCPGRFLVDFEVKMIVAYLLMNYDVEFPAEYKGQRPANRWMAEALMPPSGARIRIKRRS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 474,
                "End": 483
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 63,
                "End": 538
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 66,
                "End": 537
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 373,
                "End": 389
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 465,
                "End": 481
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 481,
                "End": 499
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 425,
                "End": 443
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 153,
                "End": 531
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 474,
                "End": 483
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 63,
                "End": 538
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 66,
                "End": 537
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 373,
                "End": 389
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 465,
                "End": 481
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 481,
                "End": 499
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 425,
                "End": 443
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 153,
                "End": 531
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "MIPPAHSQLVLSAAAIHTTSDLLSQVMYDLCARPELIEPLREEIVGVIKEHDGWKKTALYNMKLMDSVMKESQRLKPPVQGTFRLAREDITLSDGTFIPKGTKISVSAHNMWDPEIYPDPDKFDGYRFVRMREEPGKENSAQLVSTSPEHLGFGHGKHACPGRFFAANEVKIALCHILLKYDFKLKEGEKPRNVNSGFMLSADPSAKILVRRREEEI",
        "response#2": "MRVRILEIAIQTWTTIVTLTAEALRVYPEFLRPIVHWFLPGCRTSRKLLAEARAIIEPVLEERRKVQAEKKAAGTEKYNDTIEWFEETANGRSYDPALAQLSLSVAAIHTTSDLLSQVLLDLCARPELIQPLREEQIQVLRDNNGGLKKTALYNLKLMDSVLKESQRLKPVALVSMHRVAKKDVTLSDGTFIPKGTKISVAAYAMWRDKDIYGDDADEFKPYRFVDIPGSAQLVSTSPEHLGFGLGKHACPGRFFAANEVKIALCHILLKYDFKLVDGAPRPKNVSMGFWLNADPKAKILVKRREVE",
        "response#3": "MISWFEETAKGRQYDPAIAQMALSIAAIHTTSDLLSQVLFDLCERPELIQPLREEIVSVIKEHGWKKTALYNLKLMDSVLKESQRLKPGALVAMARMATEDVTLSDGTFIPKGTRVAVAAYKMGIDPEIYDDPEKFDGYRFYKMRQVPGQENSAQLVSTSPDHLGFGLGKHACPGRFFAANEVKIALCHILLKYDIRFADGTKPVFMNHGFILNADPSARIMVRRRKEEIDLSNVQAWK"
    },
    {
        "reference": "MTRKSILVTGASSGLGYAAVQKLAENGFYVFAAVREIRGMFSNIKNIKELKLDLANEQSIEELFIYIEATQKDYPLWGLVNNAGICVPSPLELLREFDLRQQLDTNVIGQLLVTQFALPFIRKSKGRIINITSGLGSIAVPYLGAYSIAQFAKMAFTDVLRRELKHSGVTVSVVQPGAIYTPIWDKFLVTGQEILDNSLDEKRKIYERSFIEFLKASQIGVNSVKTTRNDFAKVILDIFKAEIPETHYYVGDDAKNFSNKSKILTVTEIDEWFDLQSPTESEFKKI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 126,
                "End": 134
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 146,
                "End": 165
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 74,
                "End": 85
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 22
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 120,
                "End": 136
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 167,
                "End": 184
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 194
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 186
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 126,
                "End": 134
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 146,
                "End": 165
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 74,
                "End": 85
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 22
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 120,
                "End": 136
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 167,
                "End": 184
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 194
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 186
            }
        ],
        "ipr_mapped": [
            9,
            7
        ],
        "response#1": "CRVSAQRAATQWRSVLPREAATRRVQPVGSLTGVSRLALLPAPPLLQDTRREMGGRRLDGKVAIVTGGASGIGEATVRLFAAEGAKVVIADIQEDRGKELAASLGSGNARFVRCDVTSEADVKAAVETAVETFGRLDIMFNNAGICAESPTSELTEEDWDRVMAVNLKGVFLGMKHAIRVMEKRNSGSIITASSVETAVETFGRLDIMFNNAGICAESESPTSELTEEDWDRVMAVNLKGVFLGMKHAIRVMEKRNSGSIITASSVAGLVGIVRSPAYTASKHGVVGLTKNAAVDYGHKGIRVNAIAPGTIDTPLLRRVTSNGDEKAKEKMLERTPLKRLGQPEEIAYAALFLASDESSYVTGVVLPVDGGYTASQPALLFRTSKPPSDTSEEAKVKSKL",
        "response#2": "MASSTPSSSSSSSSSSSSSSSSSSSSSSSSYSAGPPPPPRQTKGMGRLGNKVAIVTGGASGIGEAIARLYAKEGAKVVIGDINAEAGQRVADSINQEVGSGRAVFVQTDVSKEEDVEKLVQTAVDTFGRLDVACNNAGIAGHVGVRASDVTTADTDTEVFDRVMAVNLRGVFLCMKHELRQMLKQKSGSIINTASVAGLVGICAGPAYTASKHGVVGLTKNAALTYAKQGIRVNSICPGGIETPLLANYTPPEFLEEMKKGMKDVHPLGRIGKPEEVAYAALFLASDESSYVTGANLVVDGGFTANAAFPPPPPSSSSSSSSPPAPPPPPPPPPAPPPPPAPSLPPPPPPPPPPPPPPPPSPPPPPLS",
        "response#3": "MAATNGQENGHSNGLSNGTNGHANGHSKLGRRLDGKVAIVTGGASGIGEATVRLFHSNGAKVVIADILEDSGKRVAEELGKDRCIFVKCDVTKEKEVENAVQSAVSHFGRLDVMFNNAGICLRKAVEETTEEDWDKVMAVNVKGVLLGCKYAVAQMLKQEPVDGSRGSIINTASTAGLVSSPVLQAYSASKHGVVGLTKNLALDMAKRGIRVNAVAPGFIETPMTSETLEEPGGRKVNKRLASISPVLQAYSASKHGVVGLTKNLALDMAKRGIRVNAVAPGFIETPMTSETLEEPGGRKVNKRLASIPLQRVGKPEEVAYAVLFLASDESSYVTGSVLTVDGGFTASLPYPELKQERFTPQTNGGTK"
    },
    {
        "reference": "MVCVPSSSSVMELANLISQSIPKLQDESPQRANDARGNVIEACSKMLALVTSPAEMLKEMVLINLASLQVINHYQIASVVPLNGHIPISELANKCGLPVDILRRILRQAMTYGAFSEPEPDCIAQTDVSREIPRLSPLLTYQLDVCLPSMVRLLDWLKDVDGEHACAYQIAHDTKDTWWSYASKRPELIENYGKYMALITSGGAHDVSYVLKGFAWEKLGNAVVVDVGGADGFVGISLAKEYPNLAVIVEDNLGLKDSADDNIPQHLKSRVVFLPHSFFKPQSALSRDADVFLLRHILHDWNDNDCRAILQALAASMKPGASILVAEQILQRPGAASWQRERVMRALDMQMMIQFGSKERAYEDWDALFKSVDPPLEIVDCVQPVGSADSFMELKRRA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 135,
                "End": 395
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 138,
                "End": 373
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 153,
                "End": 371
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 63,
                "End": 130
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 56,
                "End": 396
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 49,
                "End": 131
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 135,
                "End": 395
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 138,
                "End": 373
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MRPGRPPARRPRRPLPRARGATPPPPRDRAATGGTAVTETTERTTERTATTAEFFDRLYAEDRTPWDIGKPQPELVAALDGLDLRGKRVLDLGCGPGTHALYAAQRGAAHVTGVDLSDVALAKARERAAEQGLADRVDFVRADVRDVAADERLAGRFDVVVDSATFHFLLTDEDRARYARNVHGLLAPGGRFVLVAFSRERFGERMEDGPVYAADADTTRALLTDAGFTDVRVEEAVVRMTAEQVRERARRLGRDPDAPEHAGDDDDEPPVRLVVTATRPD",
        "response#2": "MSAEQLGIHLSERQQQQLERYVELLTQWNRAINLTAVREPQEMITRHILDSLSLLPHFKPEQHNRWLDVGSGAGVPGIPLAIAFPEQQFTLLDSLGKRVRFLRQVITELELTNVSAIQARVEELPAAERESYDGVIARAFASLAQLASYCQPLVVEGGRFYALKGQHPQEEIDALPQHWQAQCTPLTVPMLEAERHLVVITRKPSA",
        "response#3": "MLLAPIGSGVQRALDVGTGSGIWAIDMGKNESCEVIGTDLSPIQPSVPPNVRFEVDDVEEDWLWPNNHFDLIHIRMLTGSIRADWPRLYRQILRHLKPGGYFEQVEIDFAPRCDDDTLPEDCALRKWSNLFIEASEKFGRTFRVATPISKKLIVDAGFVDVHETVIKCPIGPWAGKGGGVFEMALLPLSRALGWTENEIRVYLVDVRKEIKAYKSYSNFYVVHGRKP"
    },
    {
        "reference": "MEELTRSLVNDVEVLNNHFVSTGHPLPSFDRHTPTVVLPNDASPDAHAARERILDNALRLFQLAAGPSAYLLNLQTGYQYASCVRWLCHFQIFHLVPLEGSIAYADLAVLAKAPEPQLISVVRMAMTNGLFLESPPQHLAHSATSALLRNDADFHDWAVTMSDLSFPTAFAMVEAHERWPNSVEGNQTAYNIAVGSELPFFSHLAEQSDRKRQFAGFMRSMARSQGTDVEKLAEGWDWAALGQACVVDVGGSTGHTSVALARKYPDLNFVVEDLPEVVAEGPGYLSYLDDAQDLKSRIGYRAHSFFDPQPVQDADVYMLRMILHNWSFDDCVRILSRLVQTLKPGARIIIVDIVLPDPGVVSASKERLLRVQDLIMQQVFNSMERYLENWMDIFRKVDERLEVKRIVEPPGSLMSLIELSMAA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 156,
                "End": 415
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 420
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 184,
                "End": 395
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 156,
                "End": 415
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 72,
                "End": 421
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 420
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 68,
                "End": 156
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 62,
                "End": 152
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MATATTSPMTLATLSRLAGASLHEVEEAEAEASAPAPISPPPHPPSIEANAVDHDADADSDYAPSTDTRSSTTSLASSILQYRQENGRTYHRYKEGKYFLPNDETEQDRLDLQHHIFTLTLDGKLYLAPLENPQRILDVGTGTGIWAIDMADKFPSAQVIGTDLSPIQPSPPAWVPPNCRFEIDDVEEDWTYPNNHFDLIHIRMLTGSIADWPRLYRQVLDHLKPGGYFEQVEIDFDPRHDPGPNTQKWCDLFVEASEKFGRTLRVARHSKQMMTEAGFVNVTEVVKVWPLNPWPADKRLKELGAWNQLALTEALSALSLRPFTALGWSPSEIQVLLADVRKEIKAYQSYANNYFVYGQKP",
        "response#2": "MPRDEKEQDRLDLQHHLFTLTLDGKLYLAPISDNPQRILDVGTGTGIWAIDMADKYPSAQVIGTDLSPIQPSWVPPNCTFQVDDVLEGLPFPDNHFDFVHIRLLIGSVSPEDWPKLYSEILRVLKPGAYFEQVEIDFGIRDPGPDTQRLCDWDIEAQAKFGRPLNVAVRAKGWMEEAGFVDVVETRFQLPINPWPQDPKLKELGRWYNLALTAGLEAFSMALVHAT",
        "response#3": "MASAEQHPHPPPPPPAEAEDTDSALGPSDTASSTTSLASSILQYRFENGRTYHRYKEGKYPLPNDEREQDRLDLQHHLFTLTLDGKLYLAPIGQNPQRILDVGTGTGIWAIDVADKYPSAQVIGTDLSPIQPSALVPPNVRFEVDDVEDPWTYSQPFDLIHIRMLTGSIADWPRLYRQTLNHLKPGGYFEQVEIDFAPRSDDDTLPPDSALAKWCNLLVEASDKFGRTLRVAPLSKELMVEAGFVDVVETVYKWPLNPWPKDPHYKELGAWNYLNLTEALEALSMAPLTRALGWTPSEIQVLLVDVRKELKDRRIHAYYPIYCVYA"
    },
    {
        "reference": "MVNIYIFGDQTVRVDDAVHKLLHVKNNPILKSFLDGSFAAIRKQIFLLPANERTSLPDAHTLPLLLEAVRRGRRHVALESALVCLCEIGQYIALLQTTDLCHPPTGSILVGFCTGSLAAAAVSCVRTSIDLLTLGIEAVVVAFRVGMHVARRANALGGDGGSQWKPWSLAVTDGSESETEKILEEFTRDEVSGVHVANRHDAYILAKGLPAIMKPYVSAAGSNTLTISGTPRVLEALKASPHLRGTKSLPVSIYAPYHAAHLYNEADVESIFACKPVESALFHRELRTPLISCATGTVLKEKTFGDLLRALVMEILTCQIRFDKVEESIVQHTPGATAQLIPIHTNIAPRMKTSLTQVGLQVECFKAIANQEPAAEALSESPSNDSSKIAIIGFSGRFPEADGLNEFWELLQQGLDVHKPIPADRFDLEAHYDATLREKNTSRIKHGCWIRSPGSFDARFFQMSPREACQTDPAQRLALLTAYEAMEMAGFVPDRTPSSQRDRVGVYYGMTSDDWREVNSSQDIDTYFIPGGIRAFVPGRINYFFKFSGPSITVDTACSSSLAAIHTACNALLNSDCDTALAGGTNILTNPDNFAGLDRGHFLSSTGNCKTFDDDADGYCRADGVGTVILKRLQDAIADNDPIFGVIVGARTSHSAEAVSITRPLADAQAHLFRKLLAESGIHPHEISYIEMHGTGTQAGDAVEMKSVLDSFARDDSRAPDRPLHLGSVKANVGHGESASGVTALIKVLLMMQKNRIPPHCGIKGRINRHFPTDMEYRNVHIPFMETDWTRPQEGKRRSFINNFSAAGGNTAVLVEDAPLLEQSRAISSPDPQRYHVITLSARSVRSLSKNMRALGEFIGSETSPGLLARIAYTTTARRMHHSYRVAFVGNDLQEVKRRFLDTDVTEAIKPCPTKSPGVGFLFTGQGAQQTAMARELYDRFTSFRADILEFEAVGRGHGFPSILPLITGAVDVEELSPMIVQLGTVVIQIAMARLWQTWGLTPEYALGHSLGEYAALQIAGVLSISDTIYLAGSRAALLEKRCTAGSHGMLAVKASVAHLEEALKGMQVEVSCINGFDDTVLSGTNDEIDRASKELSELKVTFKRLILPFAFHSSQVDPILEELEHIASQLSFQPPRIPIVSPTVGHIITDEGTIGAQYIRRHCREPVNFLGAIQAAQGSGICNSGALAVEIGAHPILTRMMKAAVGSSVTVCSTLSHREDMFKTLTESLSVLHLAGVRLNWDEYHRDFNNQVVMLPAYSWDYQDYWIQYQNNFCLTKGSPERSESVDAIQPMSTRLSPSVQKILEEEMTAAQASIIIESDITDPELLPVALDHKVNGVTLCPSSLYADIGHTLGTYLLGKKEDVTDYKIDVSNMAVEKALVVKGTGPQLFRASLDMDWNMLRGMMKVYSVNNMGTLTTHHAQCTIELQRPHQWQEGWNRQLYLIQRSIEQLKKGVEEGWTHKMRRGVAYRLFSSMMQYGPSYQAMEEVIFDSSGLEATAQVRLQSTTGRYSFNPVWSDSLGHITGFVTNCNDSIDLTENLFVNHGWGFMRCVEPFSPDTVYQTHVKMQPVDGNNGFYVGDVYVLNDHRIIAQYGAVTFQKVARRVLEMLLPATTSKGRSSNIRPRNVGTAQSAKIVQSKRRTQTPHVEDAWQQVLEMIARELGVDPGQLTEDVNFTDMGVDSLMSLTIIGNFREFLSLDVPWSLFEDCPSVQSLRIYLNMSSLSESDSIETSSYPTPDESTTTTITSPSGSDRNVGRNSGIDGVGTTVGLVLSILAEEIGVNVRDLSNADGLSELGLDSLLSITALGRVRDETDLDLPSDFFLEHSSVAAITAALHAIFGSTEQGPEQSLITSHPPAMSINLQGDEGCPQTLFLFPDGSGSSTSYSALPTISKDVRVYAMDCPYLKRPNELAKCQLQDLTPVYVAEIRRRQLRGPYSLGGWSAGGIAAYEAAQYLVDQGERVERLILIDSPNPMGLGKCPPHFYRFLEEAGVFGVHGGRKPPAWLLQHFQAFNDVLSQYTLEPFRPADATPNTTLIYAQDGVCKSPRDPRPERHPGDPEVFSWLLENRVDMSCNGWDQLLGEDNIHLGTVFDANHFTIVRTPAVVRLSEIVRMAMSRKFQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within Thiolase-like, ACP-like_sf, ACP-like_sf, Thiolase-like, ACP-like_sf, AB_hydrolase_fold, AB_hydrolase_fold, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1795,
                "End": 1810
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1646,
                "End": 1723
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 384,
                "End": 760
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1772,
                "End": 1836
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1653,
                "End": 1715
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1649,
                "End": 1720
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1768,
                "End": 1837
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1678,
                "End": 1693
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 383,
                "End": 826
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1648,
                "End": 1722
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1861,
                "End": 2113
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1855,
                "End": 2116
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1652,
                "End": 1723
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1769,
                "End": 1840
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1763,
                "End": 1840
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1768,
                "End": 1844
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1795,
                "End": 1810
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 1302,
                "End": 1608
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 387,
                "End": 636
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1646,
                "End": 1723
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 384,
                "End": 760
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1772,
                "End": 1836
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1653,
                "End": 1715
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1649,
                "End": 1720
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1768,
                "End": 1837
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 549,
                "End": 565
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1678,
                "End": 1693
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 645,
                "End": 763
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 921,
                "End": 1239
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 383,
                "End": 826
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1295,
                "End": 1612
            },
            {
                "InterPro-ID": "IPR030918",
                "InterPro-Name": "PT_fungal_PKS",
                "InterPro-Type": "DOMAIN",
                "Beg": 1299,
                "End": 1612
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 920,
                "End": 1223
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1648,
                "End": 1722
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1047,
                "End": 1105
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1861,
                "End": 2113
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1855,
                "End": 2116
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 385,
                "End": 1642
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1463,
                "End": 1604
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 389,
                "End": 820
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1652,
                "End": 1723
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1769,
                "End": 1840
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 919,
                "End": 1208
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 922,
                "End": 1220
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1763,
                "End": 1840
            },
            {
                "InterPro-ID": "IPR001031",
                "InterPro-Name": "Thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 1872,
                "End": 1976
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 155
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 386,
                "End": 817
            },
            {
                "InterPro-ID": "IPR032088",
                "InterPro-Name": "SAT",
                "InterPro-Type": "DOMAIN",
                "Beg": 5,
                "End": 258
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1768,
                "End": 1844
            }
        ],
        "ipr_mapped": [
            35,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MTFPRSSPYTSSTPSSSPTRLSSPPSSSPSPPPHHSPSSVSISAFCCLPTERRGASSPLPPSTSSSPSSSSPIPSPSSSPPLPNPPRLLSSSSSTNSPPQTHPPSTPPPPTPQPRPARLLSRELRGRWERVRRRRSISPSVPMAIRYEGHGMPRGRRSVEEDGEEGEGGEGQEEAEGGRGGRGGGRGRRGEKIVAREERRGEGGRKEEGVRRH",
        "response#2": "MVKLLWYVCCFLRYSLSERTMLLKTSCLKLLLNSYPSPIKFCFLPLIRHSLSSFHSRVLSSVKLISSLLSKPSRPFSPFLLPPLSLLPLPHHLTTPSSSPSSSTPRPSSSTSLLSPSSLPSSSPSISTRTSSVASWSSPVVLPLPFPIFFLFLHLLFPLVPPFPSPLLLLRSLLPIPHPHKPPSPLLLSLLSSPASGGSR",
        "response#3": "MNLLFKKNLKNFYDFKKKIKIFKNKINFLKKNFNFKNKLFLILLNKKINFFYFLLKNLSLNNDIFSKNFKKNNFKIKKIFFKKNKFFINNNNNFFYINYLNNFNNFFKNFFYKLINNKNIFNLSNFKLINFDFLKIFIKNKLIIFFKNLIIIKNKNKNLIFSIKNIINFIKFNLIIFKNNFNKNFLFLLKIKNNNKKKIKIINKKNFFNQNLFLNKNFKKINSIKNNNLIKYNFFNFKNNLFFYNIINNIFYNYFNIKNFFKIIIFKNKKIIILKNNYIKKNNLIINNFLKIINNKNNNKIIIFKNIIKFNNFKLIKILKIFNIKNILLNNIKTFLKIKLINKKKIIIIIKNFKNKKIIFIKKILF"
    },
    {
        "reference": "MQRNILWISVVAAFGVFHFGECTYQDSGEDSSSMTEESRCDGPPHASRGLMNIPGWFYDGSRDQCRRYHFPDQQFDMAKNKFKTVTECRKSCRSTVPLQCFKKPPQTIRTMGLPVSTYNSTQGECVTIAVRPGQTGPNIFRREVECNETCRDPEYGKCAPLHIVDCGGSTGNHYNLDKQTCEKTTKNKCGPFATLEDCFKRCARYIQRKCNIPLLKSEYCDIVDLRYWYNSESKQCEEIMGCADDVYNFPTAKECWETCSSKEESRCLQPPDLGKLGIGRTRYYYNITSNRCLTTTHVAFWQNTEKKNNFKRRSDCENTCRPKHKDVKKL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Kunitz_BPTI, Kunitz_BPTI, Kunitz_BPTI, Kunitz_BPTI, Kunitz_BPTI, Kunitz_BPTI, Kunitz_BPTI, Kunitz_BPTI that are essential for its biological function; 2. The protein should belong to TFPI/VKTCI-like that shares evolutionary origin and functional similarity; 3. The protein should be classified within Kunitz_BPTI_sf, Kunitz_BPTI_sf, Kunitz_BPTI_sf, Kunitz_BPTI_sf, Kunitz_BPTI_sf, Kunitz_BPTI_sf, Kunitz_BPTI_sf sharing conserved structural features; 4. The protein must be able to perform the serine-type endopeptidase inhibitor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004867",
                "GO-Name": "serine-type endopeptidase inhibitor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004867",
                "GO-Name": "serine-type endopeptidase inhibitor activity "
            }
        ],
        "go_f_mapped": [
            3
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 40,
                "End": 92
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 97,
                "End": 153
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 202,
                "End": 260
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 210,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 40,
                "End": 93
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 266,
                "End": 321
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 40,
                "End": 165
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 96
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 267,
                "End": 320
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 38,
                "End": 93
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 208,
                "End": 260
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 265,
                "End": 321
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 259,
                "End": 323
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 205,
                "End": 263
            },
            {
                "InterPro-ID": "IPR050098",
                "InterPro-Name": "TFPI/VKTCI-like",
                "InterPro-Type": "FAMILY",
                "Beg": 241,
                "End": 321
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 264,
                "End": 329
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 40,
                "End": 92
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 97,
                "End": 153
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 202,
                "End": 260
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 210,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 40,
                "End": 93
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 266,
                "End": 321
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 40,
                "End": 165
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 96
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 267,
                "End": 320
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 38,
                "End": 93
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 208,
                "End": 260
            },
            {
                "InterPro-ID": "IPR002223",
                "InterPro-Name": "Kunitz_BPTI",
                "InterPro-Type": "DOMAIN",
                "Beg": 265,
                "End": 321
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 259,
                "End": 323
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 205,
                "End": 263
            },
            {
                "InterPro-ID": "IPR050098",
                "InterPro-Name": "TFPI/VKTCI-like",
                "InterPro-Type": "FAMILY",
                "Beg": 241,
                "End": 321
            },
            {
                "InterPro-ID": "IPR036880",
                "InterPro-Name": "Kunitz_BPTI_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 264,
                "End": 329
            }
        ],
        "ipr_mapped": [
            3,
            4,
            5
        ],
        "response#1": "MSISKIVFCFLVCSILLSLNNGQEIKSDLHPDFCLLPSDHGRCRASMPRWYYNSDSKKCERFIYGGCEGNSNNFETLEECTATCQADLATLLMSDLHPDFCLLPSDHGRCRASMPRWYYNSDSKKCERFIYGGCEGNSNNFETLEECTATCQGFCLLPSDHGRCRASMPRWYYNSDSKKCERFIYGGCEGNSNNFETLEECTATCQG",
        "response#2": "VVAGSSVASKQGSVNELFTTKQIIRGERPAFCNLPKDTGKCRANFRRFYYNTESGKCETFIYGGCRGNANNFKTIAECNQTCVPLEAEYGEAEYVEAGSSVASKQGSVNELFTTKQIIRGERPAFCNLPKDTGKCRANFRRFYYNTESGKCETFIYGGCRGNANNFKTIAECNQTCVPLEAEYGEAGSSVASKQGSVNELFTTKQIIRGERPAFCNLPKDTGKCRANFRRFYYNTESGKCETFIYGGCRGNANNFKTIAECNQTCVP",
        "response#3": "MVATVLLAAANEVATVVYSSGSFDVPTDAATGRPGFCGLPADSGPCRAKIPRFYYNSSSGKCEEFIYGGCEGNRNNFATIEECEKACGNEVATVLLAAANEVATVVYSSGSFDVPTDAATGRPGFCGLPADSGPCRAKIPRFYYNSSSGKCEEFIYGGCEGNRNNFATIEECEKACGNEVATVVYSSGSFDVPTDAATGRPGFCGLPADSGPCRAKIPRFYYNSSSGKCEEFIYGGCEGNRNNFATIEECEKACGN"
    },
    {
        "reference": "MKATILLFLVLAVVQLSTAAEQLKFVFVTVRGADYEVCDIPGGPKITNKDGKDSKLTEEGKNTVYQLGVKVSELYKSKLGVSKWDSSKNYWPIATNSRRSQISTLITGAGLEGDQSKRDKSWTDEELKKTSFPAMLQFWKFIDPAKCPKFFKEVSQQPEIATTLQDCASQMQEVKKHYDTVDPTKPQHVWLTYETLKKMKKQQPSKVEWASDDMMKKLRECSAKLNWLATTKTDTLRKLSGGLILSDILNDMKEITQGKAQPHATGGTSNKLSLFTTPQGLLIAKLAVFMPPGATLDGKVPTSSEVYPESGATMNTEMYEDNGTWKVKLIYYEGKDYPGKTIKLPGCEEKCPFQQFQQILTKYAVNEQEHETLCKSAQWP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within His_PPase_superfam, His_PPase_superfam sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016791",
                "GO-Name": "phosphatase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 378
            },
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 375
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 378
            },
            {
                "InterPro-ID": "IPR000560",
                "InterPro-Name": "His_Pase_clade-2",
                "InterPro-Type": "FAMILY",
                "Beg": 54,
                "End": 330
            },
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 375
            }
        ],
        "ipr_mapped": [
            509
        ],
        "response#1": "MKVTWLGHAAFKVEVNGKVILIDPFITGNPKVDVKLEDITEKVDYIVLTHGHGDHVGDTVELAKKNGATVIAPFELATYLSSQDVAGVDPSKIHGGNIGGSHTFDFGSVKFVQAFHSSSFTENGVPIYLGMPAGIVFSFAEGKTVYHAGDTGLFSDMALIGELYPIDVAFLPIGGNFTMGPEDAALAVNKFIKPKIVVPMHYNTFPLIEQDPQKFVDLVKAEGKVLQAGESVEF",
        "response#2": "MTTLVLMRHGESAWNAENRFTGWTDRPLTERGREQAEAAGRALAGERFDAVYSSPLRRAWETAKLAAEPLGAPVTREEPLYEQKRELVVARTHHFLTRTGRRGGAAGAPPGPPTRRTPAPGRPAPVPPAPLRTAPTDRPRPEGPLTVPTTTMTTLVLMRHGESAWNAENRFTGWTDRPLTERGREQAEAAGRALAGERFDAVYSSPLRRAWETAKLAAEPLGAPVTREEPLYEQKRELVVARTHHFLTRTGRRGGAAGAPPGPPTRRTRPRGRPRRVALRTAALRTGAARRAAVRKRPRRRRPPAPARRRPAGTDPERGRPGR",
        "response#3": "MKVQWLGHATVKIETGEKVFLIDPFLSGNPKFPDIEGIEKKNPVLIKDGLEAIKGEKVDYILLSHGHGDHLGDTVEIAKNNKATVIATFELANYLSSWDGVENVHPMNIGGSHDFGFGKVKFTQAFHSSSFTDEEGNPIYLGMPAGIVFETKDLKIYHAGDTALFSDMKLIGELYDLDVAFLPIGDNFTMGPKDAALAVKWIKPKMVIPIHYNTFPLIEQDPEKFKELVEKEGVKTEVVIPKPGEPVEFKGKGKK"
    },
    {
        "reference": "MKTTILLLVVLTIVQLSKAKDNLQFVFVTAKGQDHQACNYPQGPKITNIEEPDSELTEDGKKEAYEFGQKLSSEYKSRLGVTKWDSAQNYWAIAAIEKRTKKATLITAGVIAKRQSVTSKTWSDEELQKTSFPALNDFFRFINPQHCPKYIKSILSKQNDINTILGKCEAALKTVKEHYPAVNKPQHTWLVYETFKRMKQQKASNLEWLTDDIMKQLQACSAEITWFAATNSDEWRKISGGLLLTDIFTDLDQITQGKPQPYAPGGANNKMSLFTVPQVLVISHLAVITPPGTKIGSKDVTAQNIYPEDGAYVNLELFKGDKEDWKVKIVYVKGKGEPQQTIALPGCPEKCPYNKFKQILQQYAISDDDHKKACGFPA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within His_PPase_superfam, His_PPase_superfam sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016791",
                "GO-Name": "phosphatase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 377
            },
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 45,
                "End": 374
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 377
            },
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 45,
                "End": 374
            }
        ],
        "ipr_mapped": [
            509
        ],
        "response#1": "MADKTLVLLRHAKSDYPEGVDFTTSDHERPLAKRGRREAKLAGEYLADESFDLVLCSTATRARETVQPTADALDLKVRYDRRLYDSAPSDVLDVVHETEDDVGTLLVVGHEPTMSAVAVLLASEADDDEAAEKIAKKFPTSALAVLSFDGDWADLDEGDASVERLVRPKDLADAEEADEDDADEDEDEAEDEADEAEDEADEAEDEAEDEDEDEAEDEAEDEAEDDADEEADEDEAEDEAEDDEADDDADEDEDEADEADEADEAEDEADEAEDEADEADEDEADDEDEAEDEADEAEDEAEDEDEEADEADEADEADEADEADEADEADEADEADEADE",
        "response#2": "MPAVGGGGGGGGGGGGGGGAAAAAAAAAAARRAAAELEAELERAARELERELEAAAARELERELERELERELGAAAARAARRAAAELERELRRAARELRLDAAAAARELRLDVAAAARRAAARRLAAARRAAAAARAAAAGGRAAAARAGAAAAAAARAAAAAAARRRRRAAAALARALRPPAPPPRRRGGRRGGGGGRRRSASGGGGGGARPAARRRPRRPPPRASASAPRAAARTRRGGRRPTHGGGGGGGGGGGGGGRRPPPRPPPPPPPPPPRRPPGPPPPAGRRRQGGGGARRPPPRPRRRPPPPPPPRRPPPRPRRPPPPPPPPPPPPPPRAGAAPGGGGGGGGRPPRRRRPPPPPPPPPPPPPPPPPPRRGGRGGRRP",
        "response#3": "MADIKKAAAKPAAKPAAKKPAAAAKPAGKPAAAPAAKPAAKPAGKPAAAKPAAKPAAAAKPAAKAPAAAKPAAAAKPAAAAKPAAKPAAKPAAKPAAKPKPAAAPAAKPAAKPAAAAPAAKPAAKPASAGKFVEVEGVKLYVEDKGSGPTIVFIHGFGMDSTMWDYQVEHFSKKNRVVVIDLPGFGKSGPPTSLDAFPDVIKGVLDGLKVGKCVLVGHSLGGMLSTITAIKHPELVSKLILVSASPRFLKDDDYDYAGGFEEEVVDEIIEGLEENHAGFADYFATSLVADSKKNDKAAVEKVKAMVLASRPDVAVSAAKAVFLSDVREDLKKVNVPTLICHGKDDVVVPLEVSKFVNKNLKNTKLEVFAKSGHAPFYEEPEKFNKVLEGFLPKAK"
    },
    {
        "reference": "MRYAVVTGVSSGIGKAICEKFLAKGLYVFGSVRKKEDAKYFEEKYPNTFHTLVFDTTDYPAVDKAVEEIHKVVGKKGLSVLVNNAGVAKYGPIQHVPIEELRQQYEVNVFASVYLTQKLLWLLGASKEAKWQGKVIQISSTAGVMTRPMLGPYSSSKHAVEAIYDALRRELMIYGVEVVLIEPGPIKTEIWGKAKSGGNPYKDTDYGEIFAQLDKAVDEIEKIGLPVEAVAGKAWEAFVAKKPKARYVVAPKKLMFKAAMYLIPDRMLDKIFYKDLKKLTQES",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Sc_DH/Rdtase_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 248
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 133,
                "End": 141
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 76,
                "End": 87
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 153,
                "End": 172
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 127,
                "End": 143
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 20
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 191
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 194
            },
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 140,
                "End": 168
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 248
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 133,
                "End": 141
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 76,
                "End": 87
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 153,
                "End": 172
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 127,
                "End": 143
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 20
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 191
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 194
            },
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 140,
                "End": 168
            }
        ],
        "ipr_mapped": [
            8,
            9,
            7
        ],
        "response#1": "MAAAAAAAAAAAAAARRRLDGKVAVITGGASGIGKAAALLFAAEGAKVVVADIQEDPGKAVEAEIRAKGGEAVFQRCDVTKEAEVEAVVAAAVAKFGRLDVMFNNAGIELVSRVEETTVEDFDRVMAVNLRGVFLGMKHAAAGGSIINTSSVAGLVGSVRKPAYSASKHGVVGLTKAAACDYGPRGIRVNAVCPGGIVTPMLQNSAWYLKDENGQPVPGITKEQVEKFFGSATLLNRLGQPEEIARACLFLASDESSYTTGVALPVDGGLTAKVF",
        "response#2": "MTPHPAQQRPQAPAPQPAPQPAPAPQPAPQPAPAPQPAPQPAPQPAPQPAPQPAPQPAPAPQPAPQPAPQPAPQPAPAPQPAPQPAPLAGRVAVVTGAASGIGEATARLFAQAGARLVLADLDEARGRAIAAELAGAPGAPARFVRADVSREDEVAAMVDAAVAAFGRLDVAFNNAGVERRAPVAEVEAGDFDRVLAVNLRGVFLCMKHEIRQMLRQGRGSIVNAASVHGYAGVAGRAAYTASKHGVVGLTKSAALDYAASGIRVNAIAPGYIDTPLTAAVLTPEQLRARLADIPLRRFGRPEEIARAALFLASDDSSYVTGHVLAVDGGWTAANVQTA",
        "response#3": "MTETTETTAEAPRAEAPAAPAEAPAPAPAAAAAPAEAPSPAAPPETPAAAAPAEAPAAAAAPARRLADKVALVTGAGRGIGRAIAETLAREGAAVVVNYSSSEQPARDVVAAITAAGGRAVAVRADVSREDEVEAMVAQAVAAFGRLDIACNNAGVALEPMADIADLPVEDFDRVIAVNLRGVFLCMKHEIRAMRPAAEAGGRGCIVNMSSVSGLVGSVAGAAYTASKHGVVGLTKNAALHHAKDGIRVNAVCPGGVWTDMTANARYYVPGVDAPGQTREEVEARMRAGTPLGRVAQPEEIARAVLFLVSDEASYVTGVVLPVDGGSTAR"
    },
    {
        "reference": "MDVAMRVEWLATPRVILGIGAGWVAYALCLDPLRHIPGPRLNAVSMIPYARHLLAGTTVQNSVSLHQQYGEVVRIAPNEVSLICGETAFPDIYGRLFITSQTMGQIRANSAVCRVSDGKDERASKYVQGRRVLAHAFSDKALMGQEPLVQRYVDQLIDRLKEVTSANDEPVDMVKWYNWTTFDVIADLLFGEPFGCLQDLSTHQYVALLFQSLKSLRMIYILAYYPWLRFLGNLIVDKGLIQKRKEYATWVSTQVTKRINTATPRPDFMSHILANNNNRGVKLTRAEIDSNATLMTTAGSETTATLLSGATYLLLTHPRVLRTLQDEIHSEFPTYESITLEAVAKRTPYLNAVISEALRFFPPIPVGFIRRVPKGGETVSGYWIPEGTILSVSHYAAYHSERNFRDPDSWVPERWLGDERYVNDKRAAFQPFSFGPRSCLGRNLAYAEMRLILAKMVWSFEMELDEGLSRDWLQRCRVMRLWQKPELEVRVRPRVVA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cytochrome_P450_monoxygenase, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 429,
                "End": 439
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 351,
                "End": 369
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 180,
                "End": 198
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 307,
                "End": 333
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 287,
                "End": 304
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 439,
                "End": 462
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 393,
                "End": 417
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 494
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 432,
                "End": 441
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 467
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 496
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 61,
                "End": 467
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 352,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 439,
                "End": 450
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 430,
                "End": 439
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 298,
                "End": 315
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 429,
                "End": 439
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 351,
                "End": 369
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 180,
                "End": 198
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 307,
                "End": 333
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 287,
                "End": 304
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 439,
                "End": 462
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 393,
                "End": 417
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 33,
                "End": 494
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 432,
                "End": 441
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 467
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 496
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 61,
                "End": 467
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 352,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 439,
                "End": 450
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 430,
                "End": 439
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 298,
                "End": 315
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21,
            31
        ],
        "response#1": "MPKDMVAWFNFTTFDIIGDLAFGEPFGCLENSAYHPWVAVIFQAVKNAPVLLALKVYPWLDTLLDAIAKWIPPLKKARAARAEHMRKTREKVRARRAAKAEGKLDALEERPDFLDYILRHNDEAKGMTDEELEANASLLIVAGSETTATLLSGVTYFLLKNPRVMQKVTDEIRSTFKPDEITMDSVQNLKYLNAVLEEGLRLYPPIPAGMPRYVPASGGAYVDGRWVGEGTIVSIHQYAAYRSEENFGPDADEFKPERWMGPEFIDKRDAVQPFSLGPRNCIGKNLAYHEMRLILAKTLWNFDLELCPESKNWMDQKTYLLWDKTPLMVKLTPVR",
        "response#2": "MLFAGTETTASALTVTTYYILKNARVRKKLQEELDGLPADVFDDAKVRQLPYLTAVIKEGLRLSYPAPGHLPRVVPPGSKGAVIAGRFIPEGTPVGMSQYFIHRNPAVFPEPEEFRPERWLGEDVGRLERYFVPFSKGSRQCIGMNLAYSEMYLTLATLFRRFDMELYETTEKDVELKQDYVVSAPQPKSQGLRVVFKKTKH",
        "response#3": "MQHPVNVVDWFNFTTFDIIGDLAFGEPFGCLQNSSYHEWVAIIFDAVKAMIFVQAVGRYVPGLEKLARYLFPKSLIKKRDDHLALTREKVDRRLALEPKDRPDFMDLMIRHKDDKTGMTNEELHANASLLIIAGSETTATALSGTTYLLLKNPRAMQKVVQEVRAAIDSGKLSEQITSAEVAGLPYLQAVLEEGMRLYPPVPLGLPRVVPKGGATICGQFVPEGTCVSVHQYAAYHSAANFKDPFAFHPERWLPDAAHPHYDARFANDRRDALQPFSYGPRNCIGKNLAYHEMRLILAKLLWNFDLELCPESADWLTDQKSYLLWDKKPLMVRLKPVERRVV"
    },
    {
        "reference": "MPSATPVIPSQQTAIVAEGAGQLSIYHDAPVPALQPDVALVKTAAVAINPVDAKMLDYSPVPGAIHGYDFAGTIVALGSDTPPHLKVGDRVAGFVHGMNPLLPDVGAFAEYVAASADLVLKLPDTMSFEEGASLGLGLFTAGLGLFQHLQIPLSLTREPSPEASSPTKADFVLVAGGSTATGTRALQLLKLAGLRPVATCSPAHFDLARRFGAEAVFDYHDPDCAAAIRAYTKNTLAYALDCLALAETTQLCYGALGRAGGRYVTLEPFREAIAAQRPHTVTPSWLLALTIFGRKVALDGEYGREANPEDREFGARLTEQVQGLLDEGKVDVHPVRVMGGGWQGVLEGVDLVRRQTVSGHKLVYAV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity,nucleotide binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0141148",
                "GO-Name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity "
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": " nucleotide binding "
            },
            {
                "GO-ID": "GO:0016651",
                "GO-Name": " oxidoreductase activity, acting on NAD(P)H "
            }
        ],
        "go_f_mapped": [
            4,
            61,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 126,
                "End": 323
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 181,
                "End": 265
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 363
            },
            {
                "InterPro-ID": "IPR047122",
                "InterPro-Name": "Trans-enoyl_RdTase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 364
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 124
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 182
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 126,
                "End": 323
            },
            {
                "InterPro-ID": "IPR047122",
                "InterPro-Name": "Trans-enoyl_RdTase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 366
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MAETVDFRVPVIIESSKSTEKMGRLKDKVALITGGASGIGEATARLFVKEGAKVVITDINEETGQKVVEELGSDKAIFVRLDVTKTEEWEKAVETAVQKFGRIDVLVNNAGIDISKPVHEMSEEDWDKVINVNLKGVFLGTKTVWKHMVKQNYGSIVNMSSVAGLVGSVRGPAYTASKHGVVGLTKSTALYGAKHNVRCNAVCPYGVNTPMIQNAAWYTVDGKDPKKAEESRKILEERTPLKRTIEPEDIARVVLFLASDESSNVTGVTIPVDCGYTAYVGTPQ",
        "response#2": "MRLKDKVAIVTGASSGIGEATARLFAEKGAALVLTARREDRLRKVAEEIGGKAKVLVVPADITKEEEVKRVVEKAMETFGRIDVLFNNAGIELSKPIEEMAEEDFDRVMAVNLRGVFLMMKHVARHMRERKSGSIINTASMAGLVGKRGQANYVASKHGVVGLTKTAAYELAKYNVRVNALAPGFIRTEMTRKATEKDPRVRQVLMARTPMRRWGEPEEIARAALFLASDEASYVNGVVLPVDGGYTALGWDPEAWTQPWETEEEVDEAVRALLERMEKK",
        "response#3": "MSSGKYALVTGGAGFIGSHQVEYLLEKGYKVAVIDNLSTTPSKETIEKLEKNKNFKFFQGDIRDYKFVEKVLTEHFKEKNDEMPKIDVIYNQAAQTHVERSVEDPRTYYDTNVTGTLNLLEAIRKHTPNTKFVQASSSSVYGKQKSAPFKETDELEPLNPYGASKKAADLICHSYQHFYPNTKIAVLRYFNVYGPRDNSVIPNFTKNILKDKPLPVYGDGKNTRDYIYVDDVCRANLLAAEKVESGEVFNVGTGVEVSNLDLAKQIAKIVGKDPEKFITFVDDKRPGHDERYYADTTKLEKLGWKPKEDLEKGLEKFVKWYKENNLDDQK"
    },
    {
        "reference": "MTAAGFNSILCLRQLVRLNRRQYSAPAKSVLSGSQTNDQATPPPTSKSADKMRGWQLHNYGDIDELQLSEMLKIPQIRCSNECLVRIRATAVNPIDLAMLRGYGATVLNKMRCQPGDGIEFPLILGREFCGELVQTGMGVSLPLGSRVWGVVPLQATIGSHAEYVAVPSYCLAPAPKELDDYEAASVLYAGLTAWSGLYITGGLGGPCGATTASGGGAHKRVLVLGGSGGVGTLAIQILKSQKVQVLATCSENAIEMVRNLGADLVVDYNNPQAMEELCKYAPYDIVLDCAGQGGQKAAESKYDFRQYITFSSPLLANIDKQGLGVGALKNVFDLFQTNVRSVTQRGGLVKWGFFSPAPQGIQFLQKLVEQRKLMPLIDSSYGFSELPKAFEKMKSGHLRGKIVVKLREETGD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the NADPH dehydrogenase (quinone) activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008753",
                "GO-Name": "NADPH dehydrogenase (quinone) activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008753",
                "GO-Name": "NADPH dehydrogenase (quinone) activity "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            167,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 179,
                "End": 404
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 61,
                "End": 405
            },
            {
                "InterPro-ID": "IPR037397",
                "InterPro-Name": "RTN4I1",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 406
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 51,
                "End": 203
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 81,
                "End": 176
            },
            {
                "InterPro-ID": "IPR050700",
                "InterPro-Name": "YIM1/Zinc_Alcohol_DH_Fams",
                "InterPro-Type": "FAMILY",
                "Beg": 33,
                "End": 407
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 179,
                "End": 404
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MSWTVDDIPNQTGRVAIVTGANTGIGFETARTLARHGAKVVMACRSVSKGEAAAAKIREETGGEVIVLQLDLASLQSVRSFAAQFLQKEERLDVLINNAGVMFTPYSKTEDGFEMQFGTNHLGHFLLTQLLLPLLKASAPSGEVIVLQLDLASLQSVRSFAAQFLQKEERLDVLINNAGVMFTPYSKTEDGFEMQFGTNHLGHFLLTQLLLPLLKASAPSRVVTVSSMAHRFATFPEDGIRFDRVNDEECYSTVEAYGRSKTANVLFAYELARRLGAAGGVTANSLHPGTVVTDLYRHHVPLLVKAILLAPLAALVLKTTQQGAQTTLYCALSPEVEGVGGKYFSDCEEASSSSLSYDPDAQRRLWELSERLTGVKTQAASM",
        "response#2": "MPSSSSSSASSSSSSSSSSSSSSSSSSSSSSSSSSSGCSSSSSSGSRHRRGRRRGRRGRRRGRRRRRRRSRRSGRRRSRSRWKQRQQKQRKEQKMGRLDGKVAIITGGASGIGKAAAELFAKEGAKVVIADINLSNAEATAKSINDAVAANGKGSAIAVKTDVTKEEDVKAIVDKAVETFGRLDVMFNNAGITLDKSLLRMTTEDWDKVIAVNLKGTFLGTKYGARAMVDGGSGKGGSIINTSSVSGIIGNVGQANYAASKWGVRGLTKSTALHLGEHGIRVNSIHPGVIATPMTASAIPADKTPLKRIGKPEEVAYAALFLASDESSYVTGAELLVDGGFTAGK",
        "response#3": "MRLDGKVAIITGGASGIGAATAKLFAKEGAKVVIADINEDAGKKLAAEIGADKAAFVKTDVTKEDDVKAMVDFTVAKFGKLDVALNNAGISETNFDKTIAINLKGVFLCMKYELQQMLKTGGGSIVNTASQRGLVGAPGAAAYCASKHGVIGLTKAAAIDYGKYGIRLNAICPGTIQTPLIKAAIEKGVIDENEILKKTPLGRMGKPEEIAYAALYLASDESSFVTGHALVVDGGYTAQ"
    },
    {
        "reference": "MASGARYAGKVVVVTGAARGIGAGIARAFVDSGAQVVICDKDERGGRALEQELRGAVFIRCDVTREEDVRALLSDTVHRFGRLDCVVNNAGSHPPLQPLEETTAQGFRELLELNLLGTYTLCKLAFPHLRRSRGNIINISTLVGAVGQLQGVPYAATKGAVTALTKALALDESQYGVRVNCISPGNIWTPLWQELAALAPDPRAAIREGAMAQPLGRMGQPAEVGAAAVFLASEASFCTGLELFVTGGAELGSGPENFFRSLGLCVVPEDVPPPTSRPRICSYK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein must be able to perform the oxidoreductase activity,oxidoreductase activity,identical protein binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": "identical protein binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0047834",
                "GO-Name": "D-threo-aldose 1-dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0004303",
                "GO-Name": " estradiol 17-beta-dehydrogenase [NAD(P)+] activity "
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": " identical protein binding "
            }
        ],
        "go_f_mapped": [
            4,
            4,
            27
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 16,
                "End": 249
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 249
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 134,
                "End": 142
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 173
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 81,
                "End": 92
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 214,
                "End": 234
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 192
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 128,
                "End": 144
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 16,
                "End": 249
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 249
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 134,
                "End": 142
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 173
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 81,
                "End": 92
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 214,
                "End": 234
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 192
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 128,
                "End": 144
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            }
        ],
        "ipr_mapped": [
            9,
            7
        ],
        "response#1": "MLKDKVALVTGGGSGIGKAIAVAYAKAGASVVLAGRRVSVLEEVKAEAEKAASSTARVLVVSTDVTDEAQVKSLVDKALEFGRLDIAVNSAGVAMPSAVTPVTEADVDTWEKVIAVNLKGQAMCAKHEARAMLAQGLKVHTARKLKDKVALITGGASGIGEATAKLFASEGAKVVIADIQEDLGKKVAQELSSSNSAVFVHVDVSTESQVKSMVDTAVTTFGRLDVAFNNAGISTSDDLTETTTETWDKVIAVNLRGVLLCMKYEIQAMLQQEAGGRGSIINASSIAGLVGGTQVPAYTASKHGVVGLTKAAAVQYASKGIRVNALAPGEIDTPLLREAAGGDVEAFYKAVTDQTPLGRIGKPEEIAYAALFLASDESSFVTGVVLPVDGGWTAQ",
        "response#2": "MAAAAAAQRRLDGKVAVITGAASGIGEATAKLFAAHGAKVVLADIQDTRGQEVADSIRKTGSEAVYVHTDVSKESEVKTLVSTAVSHFGRLDVMVNNAGITLRASVAEFTEEDWDKVMAVNLKGPLLGMKHAVPHMLKQGLITLRASVADMTEEDFDKVMAVNLKGPFLCMKHVLPHMLRRRRGSIVNIASAAGLVGVVRSSAYTASKHGLVGLTKNVACDYAKDGIRCNSVSPYSIETPMTITALGKDRYDEINARGSASTPLGRYGKPEEVAQAVLYLASDESSFTTGANLVVDGGFTAVSPTPQIL",
        "response#3": "MAAALSARGAAACLRRAPPAPRAGTPHIRGLPTTGAQMEREMGRLSDKVAIITGAASGIGEATAQLYAEHGAKLVLADIQEEPLQRVAAAAKAKGSSVVAVRTDVSKEAEVEHLVQTAVSHFGRLDCAFNNAGVQIVEPLESTSVEDWDRVLAVNLRGVLLCMKHELRQMLHQGRGSIVNTASIGGIVGQDQSIYDVAKKKIVTSPPYTASKHGVVGLTKNVATYYGSKGIRCNTVCPGGVYTPLVQNTATYQMGADADKPAKTKEEVDATVKKFYESQTLLKRIAEPEEIARVVLFLASDESSYVTGAVIPVDGGYTAW"
    },
    {
        "reference": "MATTLTPTQRYAAGALLALALRQAQIHQSVLLGAHHHHDDDDEEQGRTSTSSGGGGGSSSSSSNSGAGADADLWTHDSHGLLRPVFRFLEIDPKAWSGLEETAASSEAKHHIGAFLRIIFEEDGESSSDRSVQELALAKGVDVMVMSLGNDSEVGNTIKGGDQDALPSSSGTDKSPGESSHDDQLGINKLTLDDIPANNHRKMALLFALLSACVADKPVSQEEEDRKSTRFRKGYDARHRVALRLLSTWLDVKWIKMEAIEVMVACSAMAAAKEQEQSQESASPKSKWEKWKRGGIIGAAALTGGALLAITGGLAAPAIAAGFGALAPTLGTLVPVIGASGFAAMATAAGSVAGSVAVAASFGAAGAGLTGSKMARRIGSVKEFEFKPIGENHNQGRLAVGILISGFAFDEDDFCRPWEGWQDNLERYILQWESKHIIAVSTAIQDWLTSRLAMELMKQGAMRTVLSGLLAAFAWPATLLAATDFIDSKWSVAIDRSDKAGKMLAEVLLKGLQGNRPVTLIGFSLGARVIFKCLQELALSSDNEGLVERVVLLGAPVSVKGERWEAARKMVAGRFVNVYSTDDWILGVTFRASLLTQGLAGIQAIDVPGVENVDVTELVDGHSSYLSAAQQILEHLELNTYYPVFVPLSAANEETDGTVAQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0052689",
                "GO-Name": "carboxylic ester hydrolase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 497,
                "End": 587
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 402,
                "End": 638
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR007941",
                "InterPro-Name": "DUF726",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 645
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 497,
                "End": 587
            },
            {
                "InterPro-ID": "IPR007941",
                "InterPro-Name": "DUF726",
                "InterPro-Type": "FAMILY",
                "Beg": 290,
                "End": 638
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 402,
                "End": 638
            }
        ],
        "ipr_mapped": [
            35
        ],
        "response#1": "RAYLDTRGTGRSDADPARYTSFDDLADDVAGVLDALGIGRCHLVGHSVSAMTGLLTAVRHPQRLASLTLIGASPRFLNDEDYHGGFEQDEIDELFAAMEADPASWQGYAALFAPVALGPGADPAAVEWLSGTFLAMRPDIALAACRTVFTSDLRAELPGVTVPTTVVQVTGDRLVPIAVSRYLADHIPGARLVELDTVDHLPHLSDPAAVAAAIAAGTREAGE",
        "response#2": "MTTGFVEVDGTRLYHEVRGEGPAVLLSNSLGTDHTMWEPQVEALAERHRVIRYDARGHGRSDGPAPFTVAGSAEDAAALLRALGIERAHVVGVSLGGMVAQQLALDHPDLVATLTLSDTTAHTPGGPEGWRARAAQAREGGTAALADGMLPRWFAPGTDPETQARCRELFAGLDPEGYAACCEALGGFDVRDRLGEVTAPTLVITGTADTATPPEAGREIAERIPGATYREIEGAHHLPQIERPEEFTAVLREHLAAA",
        "response#3": "MPRPRVRGRYVEVNGRRLHVVEAGEGEPVVLIHGLGVSAHLYWYRLLPLLARRYRVVAVDLPGFGFSDPPPEEPYTVEALAEAVAGVLEALGVERAHVVGHSMGSRVAAELAARRPDLVRSLTLVAPTVDPRRRVSAWRQLVRALRDLVREPRLAWVIVRDYLRAGPRTYFRTLRAMLTHRLEEALPRVRQPTLVVHGTRDRLVPLEWGRRAAELIPGARLVVIEGAGHAPMLERPEETARAIEEHLERAGEGRG"
    },
    {
        "reference": "MTHRRLLWALCVAALLGVVAAQAGDQQQMQPNEADALRKKWSAVEVVRDLGHIKKDLAKMIELEGAGALSQDELYFYYFRMHDFDNNNKLDGQEMMAAMFHTNHHEEDDEHDGKVPLIIPEQDIASYVDSVLRADKNQDGFISYPELRTSDLTNQI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding,hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            },
            {
                "GO-ID": "GO:0008236",
                "GO-Name": " serine-type peptidase activity "
            }
        ],
        "go_f_mapped": [
            31,
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 71,
                "End": 148
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 135,
                "End": 147
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 83,
                "End": 95
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 70,
                "End": 105
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 71,
                "End": 148
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 135,
                "End": 147
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 83,
                "End": 95
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 70,
                "End": 105
            },
            {
                "InterPro-ID": "IPR052110",
                "InterPro-Name": "ER-Golgi_Adhesion_Reg",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 150
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MDSRLLLTILALCVCSLLAKEKKDYNYDHDAFLGKEEAKKFYDLTPEESQERLGKIFEKIDLDHDGFVTVDELGDFIKKTVKDYEWVDYDVDGLFKQIDKNGDGKIDKEEFTAFLHPEDYEWVDYDVDGLFKQIDKNGDGKIDKEEFTAFLHPEDYEWVDYDVDGLFKQIDKNGDGKIDKEEFTAFLHPEDYEWVDYDDYDVDGLFKQIDKNGDGKIDKEEFTAFLHPEDYEWVDYDVDGLFKQIDKNGDGKIDKEEFTAFLHPEDYDVDYDVDRAFYEIDTNKDGKLSKDEIKDFYHDDF",
        "response#2": "MDRKTVLLLCVCVAVALSKPTDKKKDTKKVEEKKVLDRAKPVSDVPHDRDRAFHDAPLSDAKHDNDAANFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVDKIDKDHDGFVTVEELTDWIKYAQKKWVYEDVERQFKEHDLDGDGFVSWEEYKDATYGTYDNTPGDEPDWVKTDRERFVKFRDKNSDGKMDKEETKDWILPAGDYNHAEVEARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHHDEF",
        "response#3": "MADPEKLAKELFDKFDKDGDGKITLEELKDLAKKLAGGDPEKLAKELFDKFDKDGDGKITLEELKDLAKKLAGGGDPEKLAKELFDKFDKDGDGKITLEELKDLAKKLAGGGGGDPEKLAKELFDKFDKDGDGKITLEELKDLAKKLAGGGGGGGDPEKLAKELFDKFDKDGDGKITLEELKDLAKKLAGGGGDPEKLAKELFDKFF"
    },
    {
        "reference": "MKFLQIIKHLKLQNKKNALDNFVNCRTYEHISNINKLFLNNFSSTKEHSEHGQVKHENFLNSTLKYEENSQNGSTNNLKNGKYNMYVSEGNVNINEEKYKDNNISSNNTQYNNNSSNSGSLNDEGPLWKEHIDDVVNENKKKKMNRFYLDSQATTMIDPRVLDKMLPYMTYIYGNAHSRNHFFGWESEKAVEDARTNLLNLINGKNNKEIIFTSGATESNNLALIGICTYYNKLNKQKNHIITSQIEHKCILQTCRFLQTKGFEVTYLKPDTNGLVKLDDIKNSIKDNTIMASFIFVNNEIGVIQDIENIGNLCKEKNILFHTDASQAAGKVPIDVQKMNIDLMSMSGHKLYGPKGIGALYIKRKKPNIRLNALIHGGGQERGLRSGTLPTHLIVGFGEAAKVCSLEMNRDEKKVRYFFNYVKDYLTKHLDYIVFNGCQINRYYGNMNISFLFVEGESLLMSLNEIALSSGSACTSSTLEPSYVLRSIGISEDIAHTSIRIGFNRFTTFFEVQQLCINLVKSVERLRSISPLYEMELEKKNPSNDDIPKFIWT",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Aminotrans_V_dom that are essential for its biological function; 2. The protein should be classified within PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_major, PyrdxlP-dep_Trfase_small sharing conserved structural features; 3. The protein should include a Aminotrans_V_PyrdxlP_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the lyase activity,sulfurtransferase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0016783",
                "GO-Name": "sulfurtransferase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004123",
                "GO-Name": "cystathionine gamma-lyase activity "
            },
            {
                "GO-ID": "GO:0031071",
                "GO-Name": " cysteine desulfurase activity "
            },
            {
                "GO-ID": "GO:0051536",
                "GO-Name": " iron-sulfur cluster binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            32,
            156,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 146,
                "End": 524
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 158,
                "End": 408
            },
            {
                "InterPro-ID": "IPR020578",
                "InterPro-Name": "Aminotrans_V_PyrdxlP_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 341,
                "End": 360
            },
            {
                "InterPro-ID": "IPR000192",
                "InterPro-Name": "Aminotrans_V_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 148,
                "End": 515
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 148,
                "End": 514
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 146,
                "End": 524
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 158,
                "End": 408
            },
            {
                "InterPro-ID": "IPR020578",
                "InterPro-Name": "Aminotrans_V_PyrdxlP_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 341,
                "End": 360
            },
            {
                "InterPro-ID": "IPR000192",
                "InterPro-Name": "Aminotrans_V_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 148,
                "End": 515
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 148,
                "End": 514
            }
        ],
        "ipr_mapped": [
            73,
            74,
            75,
            243,
            1014
        ],
        "response#1": "MDRSRSSSHSSRPSSRSSSSRSSSSSSDRPSPSDPPSRSPSDRSPPSRSDRSPDRPDRPSSPPSPSSPSHRPDRPDPSPSPDPSDRPRSDRPDRPDRSDRSDRSPSDRSSRSDRPDPPDPSDRPDRPDRPDRPDRPDSPDSPDRSDRPDRSPSSDRPDRPDRSDRSDRSDRSDRSDRPDSPDPPDRSDRPDRPDNSDRPDRSSRPDRPDRPSRSPSSDHRSPSSRPDRPDRSPSPDSSDRPSSPSPSDRPSPRPDRPDPSDRPDRPDRSHRPDRSDPSPSSHRSDPPDPSSRSARSDRPDPPDRSDRPDRSSPSDRPDRDSSDSHHDSSDRPSPSDRASPPRPPDRPRPDSSDRSDRPDPSDPSDRSDRPDRPDRPDRPD",
        "response#2": "MDPDRPDRADRRDRPDRPDRPGGPDPRAPGAPSAGRPDRPAPRSGLSAPPPAPGPAAPGARAGGPADRPRPAPGRADPPGRPGRPDGADRPDGPDGPDRPDGTDRPDGAGRPAGRPAPGGRAPAAPAGRPADRPRGVETAAGRSDRAGRAGRRADAGDPGGRPGGSGDRPAGGPRPARPAGRSARPAGAAGPADRPGRPDRSGPRPADPPGGPDRASAARSRPPAADRAAAGDRRSGRRDRAAGRPAGPAGAAAAPASHPGTGAAGRPGGPAPDGPVARPSARPPAGPRAGRDAAGRPAAGRRAAPGNRPPDRAGRPDRAGDPDRAPGRGGRP",
        "response#3": "MTAGGRGPAGPGGPDGPGRGRRHRAGPGSGPRSGRGGAGRAGPGSAAGRRAGRRPAGRAAGPGPPGRPPAGPGAGGAGRPPAGAARGPAGARAPAVRAGLPRPPGLPGGRRVRRQPGAARSGAAPPGGRGGRGPAGRRAGAAPAPAAAPAPSAGPRPGRGRGARRPAPGLAAPGRPRPVPRAGPPLAGPAGGRRGPPGGPARRRRRPARGHPAGPRLR"
    },
    {
        "reference": "MKPHNSEKYFVKNGQPHFLISGEVHYFRINPKLWRNHLQLLKQTGADTVSTYIPWDWHEIEEDDFDFEGKTHPARNLIRFIKLCKEENLDLIVKPGPYILAEYENQGLPSWLLKKLSKNAFALDENGNVISPDLVSYLSDEFLEYTFKWYDKVMPIISKHQKEHYGPITMMQLCNEIGVFQWLSGKSDYNPKVINLYKEFIIQRYKTIEKLNSVYSTNYNSFDDLKAPSGKIKLRSDYCAYFDFHLFFREYYNKYISILKNKIRSFGINIKLTHNIPGWIYGNASELPMLISTYSEIMKNHPDIIFGLDHIPEFVSFRNAHSDLACNKILEAMQPEAPVWAAEFQAGTREHHVKAYAKDLETFYIASLAHGIKGFNYYMFSQGINPEGKGFYGKTFYFQTALDAASNKLALYDSIKKVNRFIRKEQKDLLRTNVNSEICVGFYKPYFFTELISSQLLKEKKLNVEELGLYIDPRFLREEILFNGLLRGLQTLNYNYDVVDLENCDLKSLTAYKQLWITSAEFMDAETQNLLSEFVLNGGNLILYPAVPTLDNYLNRCEILKNNFGIEFITKDSSHKVSAFGIEDVFTAFSKKQIYNDTNSKPIAFTQENEICGIRKKIGKGELTILGFAFGYTSDEHLELIDKLVKLNKIKRELFVSDKDIQFVVRENNKSRYIFFLNYHNERKTFNYRKSSELKKKKSEEISIAPFSYKVIKENK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Class_I_gatase-like, Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            184,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029062",
                "InterPro-Name": "Class_I_gatase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 475,
                "End": 657
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 388
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR054746",
                "InterPro-Name": "GLMA-like_second",
                "InterPro-Type": "DOMAIN",
                "Beg": 468,
                "End": 601
            },
            {
                "InterPro-ID": "IPR001944",
                "InterPro-Name": "Glycoside_Hdrlase_35",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 639
            },
            {
                "InterPro-ID": "IPR029062",
                "InterPro-Name": "Class_I_gatase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 475,
                "End": 657
            },
            {
                "InterPro-ID": "IPR031330",
                "InterPro-Name": "Gly_Hdrlase_35_cat",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 205
            },
            {
                "InterPro-ID": "IPR001944",
                "InterPro-Name": "Glycoside_Hdrlase_35",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 30
            },
            {
                "InterPro-ID": "IPR001944",
                "InterPro-Name": "Glycoside_Hdrlase_35",
                "InterPro-Type": "FAMILY",
                "Beg": 93,
                "End": 112
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 388
            }
        ],
        "ipr_mapped": [
            474,
            366
        ],
        "response#1": "MTAPPPPAPPPPRRPAAPPPPPPRPPPPPPGPPPPPPLPARGGPPLSLRDLLAADPGRLPAARRAVPPRLRALLARDADAARRLAAAPAGRRPADLAALADALDADLPPGDPADPDRTAARLRDAVLGHAARLLAELAAPGLLDPEPVRRALRDRPDGLDLLAEHAGPGALLPVDAVTAHLDLLLASGPDAARRRRLAADVTARLAQADPAGLLPPADPDRRAHARRLLAALDAAAGEAAARRPRRPPRPPRRAPRRRRPARARGAGAARQRRQATAAPAPARRPRRGRGGVRRRRRRPARRRRARREPRRPAPRRPGRRGR",
        "response#2": "MNPIDPSADTDPEIRRQGAEPLARAPPVEAEVVAEAARERERERARAREAEREAERERAEEAERERERERERAREAEREREAEREREREPAAAPAPAPPAPPAPVARAPAPPAPPAPPAPPAPPAPPAPPAPPAPPAPVARAPAPPAPPAPAPAPAPAPPAPAPAPAPAPAPAPAPAPPAPAPAPAPAPAPAPAPAPAPPAPAPAPAPPPAPAPAPAPAEEERRRREEEERRRAEEERRRREEEERRRAEEERRRREEEERRRREEEEARRRAEEERRRREEEARRREEEERRRREEEERRRREEEERRRREEEERRRREDDGELKDELGL",
        "response#3": "TPPPTPPPTPPPTPTPTPTPPPTPPPTPPPTPPPTPTPERERAERERAERERAERERAEREERERAEREERERAERERAEREERERAEREREERRRAEREREERERAERERAERERAEREREERERAERERAEREREEREREREERERAERERAERERAAREERERAERERAERERAEREERERAERERAERERAERERAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVPPVPPVPPVPPVPVPPVPPVPPVPPVPPVPPVPPVPPVPPVPPPVPPVPPVPPVPPVPPVPPV"
    },
    {
        "reference": "MMKINLYKLLCFICVIFLLHKNVVRSGDNMKYNDMKGLDDLSKLNDDQVKDILGLKIDGAKERIEKLFHLIDKNNDKEITEEELNTWSSFLKNEIFLKQVQAEMGQIDSDKDGFISLNELNDAFAQNLDAKEVEKHSEGLLKRFQIVDKDKDGKLSINEVGLLIDPMKDEELKELEINEILEHHDVNKDGKISLDEFKQTRSDESSGVKKDDEMALDDFNFFDANKDGFIDKEEIIKVYFDPAHESGAINVNEIKENIFEGKKITYDLWNEKALKIAVTSLTDYGDVIRYPEDFKLDIGKNVILPTARSRAFEDDDMDADNTEDDKDEADDASQQKSPAIDEL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair, EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            }
        ],
        "go_f_mapped": [
            31
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 210,
                "End": 245
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 59,
                "End": 94
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 214,
                "End": 242
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 176,
                "End": 204
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 139,
                "End": 167
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 63,
                "End": 91
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 99,
                "End": 127
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 185,
                "End": 197
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 172,
                "End": 258
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 108,
                "End": 120
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 223,
                "End": 235
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 72,
                "End": 84
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 95,
                "End": 130
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 60,
                "End": 199
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 135,
                "End": 170
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 140,
                "End": 199
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 61,
                "End": 123
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 148,
                "End": 160
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 172,
                "End": 207
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 216,
                "End": 238
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 210,
                "End": 245
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 59,
                "End": 94
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 214,
                "End": 242
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 176,
                "End": 204
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 139,
                "End": 167
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 63,
                "End": 91
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 99,
                "End": 127
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 185,
                "End": 197
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 172,
                "End": 258
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 108,
                "End": 120
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 223,
                "End": 235
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 72,
                "End": 84
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 95,
                "End": 130
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 60,
                "End": 199
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 135,
                "End": 170
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 140,
                "End": 199
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 61,
                "End": 123
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 148,
                "End": 160
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 172,
                "End": 207
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 216,
                "End": 238
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MAKKKKEEEEEEEEEEEETEADLKEAFDLYDKNGDGKISAEELHTVMKSLGEKCSVEDCKRMIAKVDADGDGFVDFNEFKEMMKKKPGFFKKKKKKKKKKEEEEEEEEEETEADLKEAFDLYDKNGDGKISAEELHTVMKSLGEKCSVEDCKRMIAKVDADGDGFVDFNEFKEMMKKKPGFFKKKKKKKKKKKEEEEEEEEEEEEEETEADLKEAFDLYDKNGDGKISAEELHTVMKSLGEKCSVEDCKRMIAKVDADGDGFVDFNEFKEMMKKKPGFFKKKKKKKKKKKAE",
        "response#2": "MGKKNKSSSQPSTSPSPSHGSPSPPRGYGYGYPPGPPPPPPYPRGYGYGYPPPPPPPCPRGYGYGYPPPPRGYGYGYPPRGYGYGYGYPPPPPPYRGYGYGYPPPPRGYGYGYPPPPPPYPRGYGYGYPPPPRGYGYGYPPPPADEEADMERVFRRFDANGDGKISAEELGATLASLGLSGESALEDAKRMVDEVDANGDGFIDINEFMGLYKEEEEAEEDMKEAFEVFDEDKDGCISAKELQKVLTKLGLKEGRTVEDCKRMIRRVDANGDGLVDFGEFKKMMKRSVFNS",
        "response#3": "MELRHAVLLCCLICCALGAPKKDEKRHDDRVLHDDADSKSFDYDHDAFLGADEAKTFDQLTPEESKERLGKIVEKIDSDHDGFVTVEELKAWIKHAQKRWVYEDVERQMKEHDKNGDGKVDLEEFKDAIHPAEYDWAYVEAERFVDFRDKNRDGFMDKEETTDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATNFGDDF"
    },
    {
        "reference": "MAPHPQPEPIAIVGSSCRFPGGSSSPSRLWQLLSNPQDVSKEIPEDRFELQGFYHPKGAHHGTTNVQRAYTLDEDVRIFDAGFFNISPNEADSMDPQQRLLMEVVYEALESGGHPLEGLRGSDTAVFVGTMSVDYNDILIRDLESTPTYFSTGTSRAILANRISYCFDWHGPSMTIDTACSSSMVALHQSVKALRAGEARVAVAGGTELLLGPEQFVGESKMNLLSPTGRSRMWDADADGYARGDGVAAVILKRLSDAIADGDHIESIIRDTGVNQDGKSTGLTVPSSEAQAALIRSTYARAGLDLSNPDDWPQFFEAHGTGTKVGDPREAAAISGCFGSQPIHGNPLYVGSIKTIIGHTEGTAGLAGVLKASLAIQHGVIPPNMLLNRLNPDVKQYYTNLQIPTSPIQWPVLPAGVPRRASVNSFGFGGTNGHAIIEGYEPKASNFDGEQQQPVAPVTSFVFSATTEESLVALLQSYSNYLKINPTIDLHSLAWTLQSRRSAFAYKTAVAASTIDGLVSRLESKVKQAKSTPPTPAGVRSTPATPHLLGVFTGQGAQWPTMGAHLIQISATVRAKLEQLDHSLATLPEADRPSWRIADQLLAPKGESRLSEAALSQPLCTAVQVVLVDLLRSAGITFDAVVGHSSGEIGAAYAAGFISAADAIRIAYYRGVHAKLAQGQKGQKGAMLAVGTSWEDAQELIDLPAFAGKIRIAAHNSAASLTLSGDADAIAHAKRVFDEEKKFARLLLVDTAYHSHHMLPCSGPYIESLRACQIQVNKDRDSSCTWFSSVRADGKPMVADEELQDVYWSDNMVNTVLFADAVKRAAANESLNLAIEVGPHPALKGPAQQNISDVRPSSPLPYTGLLNRGNSDVEAFSDALGSVWTYLGPGTVDFQSYTRLVTPAAPAPKLLTGLPSYQFSRDRVHWHESRRAKKMRRRGAAFHELLGVPSPDNTDQDLRWTNFLKSSEIPWLDGHKLQGQTVFPAAGYVAMALEAGKWLAGDRSVQVLEVRNLTIDRAITFDDGAGFAVETLVALTGISPMSAAKNNSSSSSQMADFAVYACPNTGSLGLELVSSGQVHIVYGAPSFSVLASTPLDDSNMTSIDCEQFYSTLSGLGYGYNGPFHTLAETKRRLGQASATVATYAYSDDERPLIVHPTMLDVAFQASFLAQTSPGDEQLWSLHVPTSIKCVRINPELSASLPTASVELPLSAVLHEPESISLHSSVDVFTENKRETLLQVEGLIMKPFSPATAADDRPMFSTMEYGVAVPNAGVATGHEHPTDKEVVLAGVCDRVAYYYLRAWEAKAGDEEERFRHLLSTFVGGQHSSMTEAWSSDEEKDIQALISQYPESTDLQLLATLGDSFSTETLAQPLLDECFSRGVGFARASAGLARTVQQISHRYPHAKIVEIGAGRGHTTETVLSAIGDAFSSYTFTDTSDDIFGTVAETFQAHGKKIDYKAFNPAKAPSAQGFTEHSYDVAILPNSIYTSSSLQTALGNIRRLLKPGGYLVASAITHEPVRVQALLAGVSLSSDDPRASVSTWHSALRNAGFSGIDTISAEADRRVWPVSVLTAQAINDRTQLLRKPLSSFKGGFRLHEVVILAGKSWESSRLAEEISDLAGRFCDKVTVLEELPTDDDEISPMATFISLLDLSEPVFEEMSEEKMEGLKCLFELSKNILWVTHNARAGSPYHYASIGFGRSIAYEMPHLMLQFLDLDEVEDVVASSRVITESVVRLAALVEWEDKEMLWSLEPELYVEKGQVLVPRIRPNDEQNARINSLRRPVSEVVDPRQGTVRVVPQAGDGASLVLRKEPWDSSPLAMQIRQSTLHALAVTGESMLFVGIGTKEATGETVIALSSTNASRSVPLVSLPTNIADLDQSAGLLASTANHLLAASILASIPANGHLLLHEPAPDGSLASALASQAAEKNVRVTFSTNSATTGDATWIKLNPWTPEHLLKQQLPAGLTHFMDLASPESQVRKYLPLGCRPISVHDLARAQATNHSPGDDRTALLESLKGAVSRAITATATTASGSTAQTAVFPSQIRDLELPSSPVSIIDWTVEATVPAEVRPLDATRYFSRDRTYLLVGLAGQLGQSICEWMARHGAGTVCLTSRSAKADPEWQAAMQKLGTTVRFDVLDVTKREQVEKLVSELGTTCSPIAGVINGAAVFNDMLFSEMSLEVMERVTQPKIIGTKNLNEVFGTTPLDFFVVLSSLTSVIGNSGQTNYTAANAYMTGLVGERRSRGLTGSSLEIGRVAGIGYMERAGDIAREQLIRFGFMAISETDLHQLLAEAIHAGAPSSALAPVVTTGCRTARDDEEVPVAWFHDPRFSHKVIEAREQGSASEGKKSALPVQEQLAQATSKDEAFKVLKDCFAAKLAMISRLSDDQVGHNIPLVELGIDSLVAVEVRGWFLKELKTDMPVLKVLGGGSVADLWGSVAASPATVSKPAAAPPAPKSEDSSASSAGPSSGSRSPLETPSTPPVGEEAKQVNLSEAAERAAKFQEGKQPDSPAYVKSELVSFAQSRFWFLRLLIEDQTTFNVCFYYRITGNLRVGDLERAVRLVTNRHESLRTCFVADEKEADLAHQKVLRQSVVRLERKKIDRLEELHAEYAAMKTIPFDIASGKTLRLILLTLSPTENYLLFNYHHILMDGVSLQNFLTDLEKAYQRQPLGPPPRQLPDFSRSQRAAFQQGKMNEEVTYWRQQFPDGHHPVLPLLPVAKVNTRAPMKAFNVNQVQYRLSKTLVNQVKERAKAHRSTTFHFYLAVFRAMLFRFTEAKDLTIGIADANRNDSDVMGTIGLLLNLLTLRFQNESTQSFGDCLAESRDKAYEALHHSRVPFDVLLKELNVPRSASYSPFFQAFFDYRQGHQEKQQFGNTELEMVELHPGRTAYDMTLDITDSSDSALILFRTQAGLYNPTATQLLLDTYVHLLETFAENTSLDLGNVSLFSDEQRKRAVDVGRGLDLKSAWPETLPLRIDQIAATNRDRIALKDGHGRILTYAVMINRIEAIAEELQKSGVQEGHRVLVFEDATADWPCSMLAIMRLGAVYVPLDLRNPLPRLADVAANCEPAAILVDNTTAKDIDQVNVTQAKVVNVSHASVKPNKRVPNVSRGDAVAAILYTSGSTGKPKGIVVKHSGLRNEIEGYTTQWGLRAERALQQSAFTFNHSSDQIYTGLTNGGTVYIVPWSKRGDPIEVSQIIQEEGITYTKATPAEYALWLDYGNANLRKATNWRFGFGGGESLTPALLHQLAALGLPHLRFFNSYGPTEISISSTKMEIAYREKQPEGRIPCGYSLPNYAAYILDEQQKPLPVGMPGELWIGGAGVSLGYLNNPELTDYHFYPDPYATTEYLAQGWTRMYRTGDIAHLQADGAMVFHSRVAGDAQVKIRGLRIELGDIESNIVKTSDGALREAVVTLRDGDPPLLVAHVVFAPNHNITDTEAFLDHLLQHLPVPQYMVPVMAIPLDRMPLSNHSKVDRKALKALPLPRRTVSSDAVDVLSETMLQLRRRMGRGPPHGGTRPADCPIDQLLHHRGKLPSRRPPTIPHPTPVQRDGAAGRPPRSQQSQRHGQTDRRKHYSQRNRLEARIRTSTRFDGTLSLHYLRPTSP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PKS_PP-bd, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within NAD(P)-bd_dom_sf, SAM-dependent_MTases_sf, Thiolase-like, SAM-dependent_MTases_sf, NAD(P)-bd_dom_sf, Thiolase-like, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the 3-oxoacyl-[acyl-carrier-protein] synthase activity,methyltransferase activity,phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004315",
                "GO-Name": "3-oxoacyl-[acyl-carrier-protein] synthase activity "
            },
            {
                "GO-ID": "GO:0004312",
                "GO-Name": " fatty acid synthase activity "
            },
            {
                "GO-ID": "GO:0016874",
                "GO-Name": " ligase activity "
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": " methyltransferase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            152,
            20,
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2371,
                "End": 2442
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2376,
                "End": 2434
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1674,
                "End": 1768
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2397,
                "End": 2412
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1390,
                "End": 1557
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 437
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2364,
                "End": 2442
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1287,
                "End": 1562
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2080,
                "End": 2312
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 520
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2367,
                "End": 2459
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2519,
                "End": 2885
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2371,
                "End": 2442
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 2519,
                "End": 2953
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2376,
                "End": 2434
            },
            {
                "InterPro-ID": "IPR016036",
                "InterPro-Name": "Malonyl_transacylase_ACP-bd",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 684,
                "End": 749
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 3118,
                "End": 3129
            },
            {
                "InterPro-ID": "IPR016035",
                "InterPro-Name": "Acyl_Trfase/lysoPLipase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 550,
                "End": 855
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1674,
                "End": 1768
            },
            {
                "InterPro-ID": "IPR042104",
                "InterPro-Name": "PKS_dehydratase_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 926,
                "End": 1251
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2397,
                "End": 2412
            },
            {
                "InterPro-ID": "IPR018201",
                "InterPro-Name": "Ketoacyl_synth_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 171,
                "End": 187
            },
            {
                "InterPro-ID": "IPR049551",
                "InterPro-Name": "PKS_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1100,
                "End": 1250
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 10,
                "End": 442
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 551,
                "End": 870
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3381,
                "End": 3484
            },
            {
                "InterPro-ID": "IPR049900",
                "InterPro-Name": "PKS_mFAS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1253
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1390,
                "End": 1557
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2970,
                "End": 3378
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2998,
                "End": 3404
            },
            {
                "InterPro-ID": "IPR014030",
                "InterPro-Name": "Ketoacyl_synth_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 258
            },
            {
                "InterPro-ID": "IPR020841",
                "InterPro-Name": "PKS_Beta-ketoAc_synthase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 7,
                "End": 439
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2978,
                "End": 3329
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 437
            },
            {
                "InterPro-ID": "IPR014031",
                "InterPro-Name": "Ketoacyl_synth_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 268,
                "End": 385
            },
            {
                "InterPro-ID": "IPR013968",
                "InterPro-Name": "PKS_KR",
                "InterPro-Type": "DOMAIN",
                "Beg": 2083,
                "End": 2257
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2364,
                "End": 2442
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1287,
                "End": 1562
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2080,
                "End": 2312
            },
            {
                "InterPro-ID": "IPR001227",
                "InterPro-Name": "Ac_transferase_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 548,
                "End": 859
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1407,
                "End": 1508
            },
            {
                "InterPro-ID": "IPR014043",
                "InterPro-Name": "Acyl_transferase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 551,
                "End": 879
            },
            {
                "InterPro-ID": "IPR050091",
                "InterPro-Name": "PKS_NRPS_Biosynth_Enz",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 2635
            },
            {
                "InterPro-ID": "IPR049552",
                "InterPro-Name": "PKS_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1033
            },
            {
                "InterPro-ID": "IPR020807",
                "InterPro-Name": "PKS_DH",
                "InterPro-Type": "DOMAIN",
                "Beg": 943,
                "End": 1126
            },
            {
                "InterPro-ID": "IPR016039",
                "InterPro-Name": "Thiolase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 520
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2367,
                "End": 2459
            }
        ],
        "ipr_mapped": [
            70,
            7,
            233,
            45,
            46,
            29,
            30
        ],
        "response#1": "MPTTTYTTPTTTTTTTTTTTTPTPATGRRRRRRRAPATTTRRALRRATTLGLAVPARQPLAGRRAARAGGGRGRRPAPRPSAAAPAAGPAPGPARPRTDLRAGAGAAGPRPPRRRRRRRRLPRPGPRPPPPAAGPAAPAPPLRAAGAPDRIRRPPPPPAAAAAAARRPPAAGAGPAAAARARRAAAPGPPGRRLAGAGARPAGGRAAPAGGRSGGGGGGGGGGPRAAAARPGPPPSPSP",
        "response#2": "MCATLRRRPSTAPTTTSPCPRTRSTHLHRSPALSSRVPSETAEVDRRITIRRCAPLRACAARTFYARTPPAPRSRPHGHPSPPAYCPTAAVSTPPQSFALLRAPAPRRRAPRPARPRSRRTPLRRRARRLPRTHPRPSSPPPSPRPSAPPAPLPPPTAAPRSGRRPRNSRPPLRARRSAFRSALRPTRTRPSRPERRAPTRTRRSPLPSLSRRPTAASACPRRAAPPASLRPPPTSDPAIARNPRSCSSSTTTTTTTTTSRTASRSPSSRSPPPCRARPAQPPLEAAERASPAVVRAAAPRLTSRPATRRRGP",
        "response#3": "MRPSSLTASLSETARRWIDLRRVTTSQRTSWRITLHITSAHPRTLAARMVHHRSSPPCQLTCQCLKALARPERRRPRPERSRLRRAPRPLSLTRRWPRSPRTRRRAEAPPRWTARSSTRATTTTTTRPRTAPATRTRTAPTRTRTATRAPPAPPPTRAPTRPPTTPPTRPRTPPPRPSSPPRRSFSRTALYIFNVAVQRPLPPSRPAPSSRATAAARPPHITPTPPPPFPHHP"
    },
    {
        "reference": "MNKVKVGDAQVSYCIDGKGPGLVLVHGTGGDSETNWGHLMPALTNDWTVVRPDYSGSGITSDEGKQLEVKEIAAQVVAAAEAARVVPFDLVGFSLGSAVVIAIAADYPHLVRRIVLLGAFLSSRDIRQKTQFELWRDLIRTDRAALSRLILLTGFSPDFISKQGHDGVSVIINSFVSEINWEGMARQVELDLSIDVSEAARRIEKPTLVIGCSHDHIVPSSQAKSVVRIIRGAQYTELHTGHLAHIENPEEFILLLRSFLLSEDVP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more AB_hydrolase_1, AB_hydrolase_1, AB_hydrolase_1, AB_hydrolase_1, AB_hydrolase_1 that are essential for its biological function; 2. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0106435",
                "GO-Name": "carboxylesterase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 261
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 22,
                "End": 252
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 46,
                "End": 61
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 207,
                "End": 221
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 90,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 104,
                "End": 117
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 260
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR052370",
                "InterPro-Name": "Meta-cleavage_hydrolase",
                "InterPro-Type": "FAMILY",
                "Beg": 18,
                "End": 262
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 261
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 22,
                "End": 252
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 46,
                "End": 61
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 207,
                "End": 221
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 90,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000073",
                "InterPro-Name": "AB_hydrolase_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 104,
                "End": 117
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 260
            }
        ],
        "ipr_mapped": [
            35,
            36
        ],
        "response#1": "MTTTTVPTSTGPLGVRTGGPATGTPALLLHGICTSSRIWERTLEPLAARHRVVAPDLPGFGDSAPLPPAERSVAGQADRVAELLDALDAPRVHVAGHSLGTIVALELARRHPERVASLTLLNPVTTRSATGYLRGGLRALTPRGVLALADALGRRPLRAQWALLRVLSGTRAGTELMCRLAVAPGADPALVREFCRQNALNDRETVLDCLRASLTHDAEDLLATVAVPTTVVAAGRDVLVPVAEQRRMAELIPGARLVEVPDTGHIAPLERPAEVAAVLERTWAEAEEPR",
        "response#2": "MPQPPRPATTTAAAAAAATAAATTAAATAAAATRPAPAPGRTVTAADGTPLTVREHGTGRPVLLLHGVATDSSTWERVVPHLAARHRVIAPDLRGHGRSGPLPDDRCTIEDFAADAAAVLDAVDAPRCVVVGHSLGGMVALELAAAHPERVAGVALLAAAAHPLAGAPAPPAPAPPAPAPPAPAPPAPAPATPAGPRRPRRRRPRPPVRLQRAALALLRRNRALAELFVRRRLLAPGATAETVDRFCEHSRRCRPDVTLRCLAAGAAHDLRPLLPRLTVPTLVLHPRHDELIPLDRGRELAALIPGARLFELDLDCGHLPQLERPAETAAALHTFLDETA",
        "response#3": "MAPHLAPRFRVVAYDLRGHGRSPRPPDAPYTIDDYVADLAGLLDALGLERVAVAGHSMGGAVAQAFALRHPERVARLVLVATTARLRVNPLIFEAVRRDYRGFVEAALAYAFGPEALRDPARVEEWRRRWSEVPPEVAYADWRACDRFDVMDRLPEIRVPTLVLHGARDLMTPVAYARELAERIAGARLVVLEGAGHMVMLERPEAVARAVEEFLGP"
    },
    {
        "reference": "MLEILADESVGGNSPTVIINRGAKKMQWPFIGCGGLGFSKTAHFTCFDSMTQLCEEDIPCIHLPPQHRSVYKMSTENKMRAVVFHSPYKVAVEERPIPKIQDSGDIVVKVTYTALCGSDLHTFRGIEPAGTGFVMGHEVTGEVVEVGSGVKSIQKGDMVVSAFTTSCGECFYCKQGFSSRCEKSVLFGCDHLDGAQAEYVRIPNADGTVMKAPEGVEEKYLVLMADIFPTGYFAASNAFKGYTPEQISEQTVVLIGCGPVGLCALINALEFKPKHLLAVDSIPSRLELARSLGAEPWNFQQDREGLDKRVKELTNGRGADAVIEVVGLSPALRTGFDLLRPWGTISSVGVHNGEIPWAGNDAYDKNLRIQMGRCPVRSVSPQALDVLKKNQHKLGFMADKIMPLSQAVEGYELFNAMKVQKVIFKAGE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 221,
                "End": 388
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 259,
                "End": 387
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 103,
                "End": 213
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 79,
                "End": 244
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 221,
                "End": 388
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 85,
                "End": 424
            },
            {
                "InterPro-ID": "IPR002328",
                "InterPro-Name": "ADH_Zn_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 136,
                "End": 150
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MVAIITGAASGMGKASALLYAKNNVKVVLADINEEEGNKVVEEIKKEGGEAIFVKVDVSNSEEVKNMVKKTIETFGKIDYLFNNAGITRDATFLRMKEEDWDKVISVNLKGTFLCTKEVLKEMIKQKSGSIVNTSSISGIVGNFGQANYSASKGGVIAFTKSIAVEVAKYGIRVNAVAPGYIYTPMTEKIKERDKEAMEKLKDKVPLREKGLTPEE",
        "response#2": "MRLDGKVAAVTGAGSGLGAAAARLFAREGARVVVADLDGAAAERVAAEIRAAGGEALAVRVDVADAASVRAFVETVVARYGRLDVAFNNAGVGAFAPLLDMTEEQWDRVLAVNLRGVFLCMKHEARVMKERGGGSIVNASSIAGLMGFPGGGAYAASKHGVRGLTKVAALELGRYGIRVNSIHPGLVDTPMLRALLADDYEGALAAMTAAIPLGRLARPEEIAAAALYLASDESSYVTGQELVVDGGLTAARPAAPPEPPPDPAPDPSLPPPGPPARPGR",
        "response#3": "MATSLFRLDGKVAIITGGASGLGRAAALAYARNGAKVVIADLLDETGKETVELIKKEGGEAIYVHTDVSKEADVEKMIETAVNTFGRLDVAFNNAGIAAWDVTPFNMTPEGKAPYTFAEMETDIWDRTIAVNLRGVWLCMKHELRQMLKQGNGGSIINTASVAGLEGMNRLSAYTASKHGVVGLTKTAALESGKHNIRVNAICPGGIITPMTYNPEFWLPMLIPGTPEGKPSTIEEAEKAFQENTPLLKRVGTPEEVANVALFLASDAASYITGTAIPVDGGFTASNA"
    },
    {
        "reference": "MAAVGRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAGGRAVEQELLGTVFIPGDVTQEGDLQTLISETVSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEENLLGAYTLIKLALPHLRKSKGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRYGVRVNCISPGNIWTPLWQELAAATSDPRATILEGTLAQPLGRMGQPAEVGAAAVFLASEATFCTGLELFMTGGAELGYGRKASSSTLVEVPILPP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Sc_DH/Rdtase_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity,oxidoreductase activity,identical protein binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": "identical protein binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0047834",
                "GO-Name": "D-threo-aldose 1-dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0004303",
                "GO-Name": " estradiol 17-beta-dehydrogenase [NAD(P)+] activity "
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": " identical protein binding "
            }
        ],
        "go_f_mapped": [
            4,
            4,
            27
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 141,
                "End": 169
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 173
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 134,
                "End": 142
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 81,
                "End": 92
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 249
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 192
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 214,
                "End": 234
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 128,
                "End": 144
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 249
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 141,
                "End": 169
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 173
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 134,
                "End": 142
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 81,
                "End": 92
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 249
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 192
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 214,
                "End": 234
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 128,
                "End": 144
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 249
            }
        ],
        "ipr_mapped": [
            8,
            9,
            7
        ],
        "response#1": "MAIDTTIIEKLRLLWKMPAPIAFPLGILFLIPFAVVLVPPLLLYHVVKGVISKLFPSKRRLDGKVAVVTGAASGIGEATALLYAKRGAKVVLADVNEAAGKRVEDEIKKLGSSAVFVKADVSKVSEVETFVNTAVSTFGRLDCAFNNAGIEQRKPVTDMTEEEWDRVMAVNLKGVFLCMKHEIRAMLPQGNGSIINAASVVGLVGVHAVSAYTASKHGVVGLTKTAALEYASKGIRINAICPGFIDTPMTQAALQTEEAKKNLLDNTPLKRMGKPEEVAYAALFLASDESSYVTGHVLVVDGGWTVSTGT",
        "response#2": "MSLSNKVAIITGSGGGLGRAHALLFAKHGASVVVNDLGGSADGSSSPALEVVEEIKKAGGKGVAVVADVTKEDEVKGMVETAVSTFGRLDIACNNAGIQIRKPVTEMTVEDWDKVIAVDLRGVFLCMKHELKVMLQQGHGRIVNTASIAGLTGNVSGSNYVAAKHGVVGLTKTVASEYKSKGITCNAVCPGGILTPLLAEPEDVAKLVLFLASDDSKYVTGQAIVVDGGYTVY",
        "response#3": "MATAPAQDAAPQVASTEAAAQQKGRRLDGKVAIITGGASGIGEATARLFHSHGAKVVIADIQDEKGKALAEELGDACVYVHADVTKEEDVERVVKTAVERFGRLDCAFNNAGIEGVTATVADCTVEDFDRVMAVNLRGVLLGMKHEVRHMLESGGSIVNAASIAGLVGVRVSPAYTASKHGVVGLTKTAALFYASKGIRINAYCPGFIDTPMVRCAVEQSGKDPWVREPGTLACVTLHAAAAVTESDEEAAKQWAEINAKILARTPMNRIAKPEEVARVALFLASDESSYVTGAVLPVDGGYTAQ"
    },
    {
        "reference": "MLFPKDTLTREIKDLSGIWRFKADPDNRGREEKWHHQPLQDTIPMPVPASYNDITQDAALRDHIGDVWYEQTFIVPRSWSGDRMMLWIGSACHHAVVWVNGVEVASHKGGFLPFEADITRVAVPGRENRVTIVVNNVLNWQTLPPGRIKTFDDEKHPEGYRVQEYFHDFFNYAGLHRPVKLYRTSGLFIQDITITTDVQGESGVVGYSIECSQPEGEVRVKLLDEDGKEAATGKGSSGTLQVENARLWKPLQAYLYTLHVELLDSYGQLADHYQLQVGIRTVKVEGTRFLINGERFYFKGFGKHEDSDIRGKGLDQAVNVKDFNLLKWINANSFRTSHYPYAEELLELADREGIVVIGEVPAVGFTFFNYNDKVYTPDQANEETLAHHHDVLSDLIARDKNHPSVVMWSLANEAATFQDEAVPYFRQLADTARRLDPQRPITIVQWPLPDKCKVAQFFDVICVNRYYSWYQDPGALELVEHQVEWELTNWYRNFGKPVIMTEYGADAIAGFHQDPPVMFTEEYQEELLTRYHNVFDRLDFVIGEHVWAFADFATKQGITRINGNKKGVFTRQRQPKAAARMLRSRWGEMGEYPEKL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF, Ig-like_fold sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds,hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            },
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004565",
                "GO-Name": "beta-galactosidase activity "
            },
            {
                "GO-ID": "GO:0004566",
                "GO-Name": " beta-glucuronidase activity "
            },
            {
                "GO-ID": "GO:0030246",
                "GO-Name": " carbohydrate binding "
            }
        ],
        "go_f_mapped": [
            184,
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 282,
                "End": 587
            },
            {
                "InterPro-ID": "IPR013783",
                "InterPro-Name": "Ig-like_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 187,
                "End": 281
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 282,
                "End": 587
            },
            {
                "InterPro-ID": "IPR006103",
                "InterPro-Name": "Glyco_hydro_2_cat",
                "InterPro-Type": "DOMAIN",
                "Beg": 282,
                "End": 589
            },
            {
                "InterPro-ID": "IPR006104",
                "InterPro-Name": "Glyco_hydro_2_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 12,
                "End": 184
            },
            {
                "InterPro-ID": "IPR006101",
                "InterPro-Name": "Glyco_hydro_2",
                "InterPro-Type": "FAMILY",
                "Beg": 496,
                "End": 511
            },
            {
                "InterPro-ID": "IPR006101",
                "InterPro-Name": "Glyco_hydro_2",
                "InterPro-Type": "FAMILY",
                "Beg": 91,
                "End": 106
            },
            {
                "InterPro-ID": "IPR006101",
                "InterPro-Name": "Glyco_hydro_2",
                "InterPro-Type": "FAMILY",
                "Beg": 399,
                "End": 414
            },
            {
                "InterPro-ID": "IPR006101",
                "InterPro-Name": "Glyco_hydro_2",
                "InterPro-Type": "FAMILY",
                "Beg": 291,
                "End": 305
            },
            {
                "InterPro-ID": "IPR006101",
                "InterPro-Name": "Glyco_hydro_2",
                "InterPro-Type": "FAMILY",
                "Beg": 322,
                "End": 340
            },
            {
                "InterPro-ID": "IPR008979",
                "InterPro-Name": "Galactose-bd-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 184
            },
            {
                "InterPro-ID": "IPR036156",
                "InterPro-Name": "Beta-gal/glucu_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 188,
                "End": 281
            },
            {
                "InterPro-ID": "IPR023232",
                "InterPro-Name": "Glyco_hydro_2_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 399,
                "End": 413
            },
            {
                "InterPro-ID": "IPR013783",
                "InterPro-Name": "Ig-like_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 187,
                "End": 281
            },
            {
                "InterPro-ID": "IPR023230",
                "InterPro-Name": "Glyco_hydro_2_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 332,
                "End": 357
            },
            {
                "InterPro-ID": "IPR006102",
                "InterPro-Name": "Glyco_hydro_2_Ig-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 188,
                "End": 280
            }
        ],
        "ipr_mapped": [
            474,
            475
        ],
        "response#1": "MLDVLAADVERDAVQRRRAAEAAVAQRRREEAAEAAAEAARRREEAAEQRRREEAAERRREEAAEQRRREEAAEAQRRRQEAEAEAERRRQEAEQRRREEEAEAERRRQEAAEQRRREEAAQRRREEEAEQRRREAEEAAAAERRRQEEAAQRRREAEAEQRRREEAEAEAAEAEKRAAAEAAARVNAEVKRRLDEAARANADMLRAMGEKLDASAQRVAELARQNTEVKRRLDEAARANAEMLRAMGTKLDASEQRVAELARQNTEVKQKLDASEQRVAELARVNTEVKQKLDASEQRVAELARVNTEVKRRLDEAARANAEVKQRLDEAARANAELRRR",
        "response#2": "MSDRLERALDRLDEAGPEERDDVLDRVDELADRLDRDDPDDAADGLRDAADELERRGDDEAAERLRDAADRLDRVAEAEDLLDRLDRDDRDELLDRVRDAADRLDRLDRDDRDDVLDRLDRLDDPERLDEEEREELRERLDRAREALDPDERAEALDRLDRVDDEREREALRERVRELDAELDPEEREELLDRVEELVERLERDEDRDEVRDRVRERAEELAERAEDEAERERLRERVERVREGLERADDEEERERLLERVREAREVLDRDDPERVRDRAREVADALDPDDPDEVADRARDLAERLERDDEDERAEFAREFADVLDDPERAREALRELRDGE",
        "response#3": "MTPMTPPSPTPPSPAPPAPPAPAPPAPPPAAPPPAPPAPAPPAAATPSPAAASTTDEVDRRVDAQHARREAERAADAAREAQFLAQQRERRAEHFAEQERAELEERRAEHLAEVEAEARAEAEEEARERARLEEEERVRREAKLLAREERTRRWREREEAEEEARQRAEAERREEEVTERQREARRAEARARSEAERRAAEARRARREEERREEARERRAEERRERER"
    },
    {
        "reference": "MNSMHPETLMVHGGMDGLTEAGVHVPAIDLSTTNPVNDVATGGDSYEWLATGHALKDGDSAVYQRLWQPGVARFETALAELEHADEAVAFATGMAAMTAALLAAVNAGTPHIVAVRPLYGGSDHLLETGLLGTTVTWAKEAEIASAIQDDTGLVIVETPANPSLDLVDLDSVVAAAGTVPVLVDNTFCTPVLQQPIRHGAALVLHSATKYLGGHGDAMGGIIATNSDWAMRLRQVRAITGALLHPMGAYLLHRGLRTLAVRMRAAQTTAGELAERLAAHPAITAVHYPGLNGQDPRGLLGRQMSGGGAMIALELAGGFDAARSFVEHCSLVVHAVSLGGADTLIQHPASLTHRPVAATAKPGDGLIRLSVGLEHVDDLEDDLIAALDASRAAA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within PyrdxlP-dep_Trfase_small, PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_major sharing conserved structural features; 2. The protein must be able to perform the lyase activity,pyridoxal phosphate binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004123",
                "GO-Name": "cystathionine gamma-lyase activity "
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": " pyridoxal phosphate binding "
            }
        ],
        "go_f_mapped": [
            32,
            33
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 257,
                "End": 388
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 48,
                "End": 387
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 256
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 389
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 257,
                "End": 388
            },
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 386
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 48,
                "End": 387
            },
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 390
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 256
            }
        ],
        "ipr_mapped": [
            73,
            74,
            75
        ],
        "response#1": "MRRALAGYAGVPAGRVVCGNGSDELIDLLVRALAGPGRTVLLPDPTFPMYAFSARAAGARPVPVPLRPDTWRPDAPALAAAVRAHRPAAVFAVTPNNPTGGAWPLADLATALAAAPGPAVLDEAYAEFSAEPSAAELTGRHPGALVLRTFSKAFGLAGLRVGYALAPDPVAARLAAAKPPYNVCTPAQAAALAALRGPAEELRARAALVRAGRDRFAAGLAALPGVAEVLPSETNFVLARFVEPGRAAAATAELRRRGVLAKPAGPDRVRLTTGLPGPADVDRTLDALAAVLASPPPPPPPPPPPPPPPPPLPPPP",
        "response#2": "MTAPAPLPAPPPPLPRPLNLVASENRPLPEVADAVRDALTDWGPGRYSGVNRYGDPVPEEPRAAVRELTGLPSDWALQFQPSGTAALHAAAAALLAPGDTVLAPDDAYGGAEASVTAAARRTGATVRRVPLRDDAVDTDAVRAAARGARLVYVEYPVPGVLRRADLAALAAATRDAGGALLADAAHGLAHPDGPADPARAGADVTTGSLHKALRGPHGGYVAARPELAERVRELLTGGGGGPPAAMVAAAAVALRRAADPAFTAYRDRVRENAALLAAAVAETPGARVTGPSDANLLLVDLTGAGPDAARAAQAALAAEGLTAADYPRPHPDPAPPPALRLGVGPDHTAEDVRRTADALRRALARLPPPPPPPPPPPPPSPR",
        "response#3": "PGDPVLFPEPSFPVYPALARLAGARPVPVPLRRTPDGWRLDAGALADAVRRHRPRLVFAADPHNPTGTLTDPAELRELADRTGALLVLDEAYQEFAGPDAGPPPSAPALAAEHPWTVVLRTFSKAYALAGLPVGYALAPPELTGALDRARLPFPVATPAQAAAAEALRRAGPELRERAAAVRAQRHRLTAALRAAGLPVLPSTANFVLVRCPSAERTAAVTAAARERGLLLRPCPGYPGCADTIRVTALPPEQTDRAADVIAAAAPPAAPPAPPPPPEEPRP"
    },
    {
        "reference": "MTGQSAAVEGSNSALPWYRMGFHTLAEFNTYVTFVLLGMSIMMVTSAVTSAPDFVTKYFIYATGDPDAVAETPLFWNNANTFYNAGTYAMQVVTEIASLTPFMRSIPLGIRLFLGLGIPFVELVVIIAVPAATIPTQNGAIAVIMVVAMMGGLSKALCDSCTNALVGPFPTKFMNGAQWGLTVIALFMSIIQIILQVSMGSTFQDVLTISRIYFGIGIGIQVMAIAALVLLRYNPFAQKYIAEFRAAALRRRGHVEPEESQDSKEPATGDVAEAPKAGEKEVTLDAMEEADEVRAVPSDAFVAKSGAVLQATGDADRMVDLDQTKNITSTEQMLRASVWSVFKRIYPMLLCAFTIFFTTLLVFPGVFFLVPARSGWYMTIIVTLFNAGDFVARVLLMIRVLRPSPKLVIVGTFGRLAVIPLIVLCVRGFIPGVALPYVLIFLFGLTNGYFGTMSCIHCPRTPTLHYAGERSVAAMLAGISLMLGLCFGSNMSLAITLTY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within MFS_trans_sf sharing conserved structural features; 2. The protein must be able to perform the transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0022857",
                "GO-Name": "transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005337",
                "GO-Name": "nucleoside transmembrane transporter activity "
            }
        ],
        "go_f_mapped": [
            18
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 87,
                "End": 487
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 149,
                "End": 495
            },
            {
                "InterPro-ID": "IPR002259",
                "InterPro-Name": "Eqnu_transpt",
                "InterPro-Type": "FAMILY",
                "Beg": 28,
                "End": 495
            },
            {
                "InterPro-ID": "IPR036259",
                "InterPro-Name": "MFS_trans_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 87,
                "End": 487
            }
        ],
        "ipr_mapped": [
            34
        ],
        "response#1": "MTTPPSRRPRPTAGVPLPVVFTTLGALAAVAALAAPWVTSSYSISSGSRTETTSVAWHAPAGSAPLPAVVGALVVLTLVVLLVPRRLAPAVVAVAVALGLVTAVGGAVDLGVVTQQWVDAGANETGTASVETSDPSVGPVLAVIGGAVVLAAFVGAWRSRPAEARPDAPAGGAGTGTGRPELAVAFALTLVAAALAAGSIFADWRHGTGSDGSTTSVVGFAAGAAPWVPVVLVAVAVVAAGVLLATRRTRWLAIALPVVAVVLAAVSVAVGSVVTGTYFSETVAGSYDLAADAVVTATVDAASIGYWLGLAAYGVALVSLVVAVVRGVRSRRSAPVAAPGPVRDAA",
        "response#2": "MGVASALGPVVGGLLVEAFSWRWVFLINVPVGVLALLLGGRLLPPMPPAERGATRRLDPRGVVLLAAALTALLYGVIEGGSRYAWDSTPVLGLLAAGAVLVAVFVAVELRAAEPVLDLRLFRNRTFTGATGAGTLAFAAMYGAIFFLSLYLQQVHGYTAFRAGLALLPMTAVVFALAPAAGRLTDRYGPRPLTLTGLALGTAGLLGFSRLTADTPYPLLALAFLVLGTGLALVVTPLTTTAVSGVPREKAGVASAAVNTSRQLGGAFGVALLGAVTATRTGELTAAHTPAEALTAGVHTALLTAAALAAAGFGVALFLIRPKEAAAPEEAVPAPAH",
        "response#3": "MPHEAGTPAYRRTNLGLFAAGLATFALLYCVQGLLPVLAAEFEVSAATASLTVSVTTGFLALGVLFYGPVSDRLGRKPVMLASMAVATAAAAGVALAPSFELLLALRALQGLALAGLPAVAMAYLGEEIHPRHLGAAMGLYISGNAVGGLSGRLVSGAVADLAGWRWGLAAVALIGAAATVVFARGLPRTRHFTPSGGSFLRLWRDPRLAGTFATGFLLFGHFSAFWTSLTFLITAPPYSYSPGVAGLFGLAGVAGAVAARPGGRLADRHPRATTLAGLLLLAGAWLLLVPAATSLTALLVGTVLLDLAVQGAHVTNQRTIYGLRADARSRLNTGYMTAYFVGGSAGSTLSAAAWAAGGWPAVCLLGALLGAAAAAVHLTLSPGRGREAATA"
    },
    {
        "reference": "MDSAFVLPHPASMGASCILGLLLLTILRALLIPKKALPLAINHHRWDIFNRRAIQDFTANPQDLIKAGLKKVIDPQIAPRFAKGTFLVLPERYSEEVKNDERFSAYEALSRSSPQIILLELPGFESVFEGLMHNDVVLPGVAAMNRQLASLTSPMSEEVSHYLQTNWTDDPDWHTQSVSASMSGLIGQAAARIIVGPELCRNKEYHAITLSYTMSRGRALAAIHAWPRALHPLIHWFLPSCRNVRTQIRRAEKLITPILERTRRHRARGDPPQAFSTLAWSDEYARAQGRSYNATLAQMRFTSSSIHNTSDLLGKVMLRICQRPDLIEPLRREIVAAFDGGSGAQHHSLGKLKLMESVMKETQRLEPAAERVSYPPPLTPERLTGYSIVNMFRVAKETVTLSDGTTIPKGTIFGFSYQNRFDPSMYPDPETFDPYRFMRMRQDPVQASLASFTKARSTHLSFGLGRHACPGRFMANDMIKLALSHILLKYDFKLVGEELPKLEMHGFVYAREPTAQILVRRRQEEVVL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 100,
                "End": 526
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 388,
                "End": 512
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 155,
                "End": 370
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 144,
                "End": 522
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 352,
                "End": 368
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 469,
                "End": 487
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 420,
                "End": 438
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 453,
                "End": 469
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 462,
                "End": 471
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 100,
                "End": 526
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 388,
                "End": 512
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 155,
                "End": 370
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 144,
                "End": 522
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 352,
                "End": 368
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 469,
                "End": 487
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 420,
                "End": 438
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 453,
                "End": 469
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 462,
                "End": 471
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "MRFYRTPGAILVRNLLPEWICRKSLPVRREAAELIRETIEERRKSGKTYNDTIQWFEETAKGRTYDPALAQLRLAIAAIHTTSDLLTQVLFDLCANPELIQPLRDEIIQVMREEGLSNGWKKTALYKLKLMDSVLKESQRLKPVVYVTMRRVAKEDIKLSDGTVIPKGTKISVAAHAMWDPSIYPDADKFDGYRFVRMREVPGQENSSAQFVSTSPDHMGFGLGKHACPGRFFAANEVKIALCHILLKYDVKLPEDCPRPKNISFGEEVLADPSAKILVRRREEEIS",
        "response#2": "MRPAVKEAREIINKILEERRKEKEARLARGEKYNDTIQWFEEVAKGSEYDPALAQLSLSVAAIHTTSDLLSQVMFDLCAHPELIQPLREEIIRVVKENGWKKTALYNLKLMDSVLKESQRLKPVAVVSMNRVCMKDVKLSDGTIIPKGTKVNVAAYKMNTDPDIYPDPEKFDPYRFVKMREDTVKAQEKDKEVTHTSAQLVSTSPDHLGFGHGKHACPGRFFAANEVKIALCHILLKYDFKFEEGSKPKSINSGFFLSADPTAKLMVRRRKEEISLD",
        "response#3": "LHLVAQMSSRVFLGPELCRNEEWLAITKDYTVNAFVAAEELRLWPEFLRPIVHWFLPSCRKLRKQLARAREIITPVLEERRLEKEKNNRDNENDNSNGRDEEETPSRKTKTYNDTIEWFEEVAKGRSYDPAVAQLSLSVAAIHTTSDLLTQVLLDLCAQPELIQPLREEIISVINEHGWKKTALYNLKLMDSVLKESQRLKPIGAVSMMRKVVKDGVTLSDGTFVPKGTMVSVAAHAMWHDPNIYPDPEKFDGYRFVRMRETPGNENSAQLVSTSPDHLGFGHGKHACPGRFFAANEVKVALCHILLKYDIKLEEGAKPRLIANGFIFSADPNAKILVKRR"
    },
    {
        "reference": "MSEVERALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIRKALNWPAIGKWTPKYLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVVRRLDDPTGAVHYIQKQNSNLSVDLPELAADLRVSDLDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHKDFVLIPPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEYARAKPLKVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWYDLDYDSRYCYYRMLEQMTSARSG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within RmlC-like_jellyroll sharing conserved structural features; 2. The protein must be able to perform the 2-oxoglutarate-dependent dioxygenase activity,hydrolase activity,ferrous iron binding,identical protein binding,2-oxoglutarate-dependent dioxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016706",
                "GO-Name": "2-oxoglutarate-dependent dioxygenase activity"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0008198",
                "GO-Name": "ferrous iron binding"
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": "identical protein binding"
            },
            {
                "GO-ID": "GO:0016706",
                "GO-Name": "2-oxoglutarate-dependent dioxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016706",
                "GO-Name": "2-oxoglutarate-dependent dioxygenase activity "
            },
            {
                "GO-ID": "GO:0004175",
                "GO-Name": " endopeptidase activity "
            },
            {
                "GO-ID": "GO:0008198",
                "GO-Name": " ferrous iron binding "
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": " identical protein binding "
            },
            {
                "GO-ID": "GO:0106155",
                "GO-Name": " peptidyl-lysine 3-dioxygenase activity "
            }
        ],
        "go_f_mapped": [
            303,
            19,
            112,
            27,
            303
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR014710",
                "InterPro-Name": "RmlC-like_jellyroll",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 315
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR041667",
                "InterPro-Name": "Cupin_8",
                "InterPro-Type": "DOMAIN",
                "Beg": 35,
                "End": 298
            },
            {
                "InterPro-ID": "IPR003347",
                "InterPro-Name": "JmjC_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 124,
                "End": 310
            },
            {
                "InterPro-ID": "IPR014710",
                "InterPro-Name": "RmlC-like_jellyroll",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 315
            },
            {
                "InterPro-ID": "IPR003347",
                "InterPro-Name": "JmjC_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 124,
                "End": 308
            }
        ],
        "ipr_mapped": [
            47
        ],
        "response#1": "MINQNFNFYYYTNKIKNLNFIMIFNKKKKIKSNINFILYNKNSNKNFFNIFKKKNFKIKKFNLNFNYLNLIKFNLKIYFLIIFNKIFNWKKNFKKIYYIKNLIFKKNLNKKFFLNLNLNFKNLKFNFKIIKNKFNLIFLNFNFKNLIKSFLKFNYKKYLIKKNIFNKIKIIKKIINLKNFLNFKIKIIFNLILNYFKKKNFFILNLNLYNFNLNLKNLKKKKNYINFFFLNFKKIFFNFLKNKLFKILNYLKIKIKLYYLNKKLI",
        "response#2": "RAVPAASRGGRAPPLAAPGPDRRGSGSGRRRRPGRGAALAAGGPGGAGSVRRPGRAGGRDRRATAPATGPGCPGRGRGLSPRPAARPRGGGPPAAGAGPARAAGGPAAGSRAPSAGAGGSAPAAGLPGTAQRATGGARLPPGTARPGRSHLPGRRAARGARPGAARRAGRPGAARPAGGRAAFVRGSDPPVPPGPPPHARAPRRLGPPSAPGRRSRSARRRCPRARLRPARLGVLPPLGARRRPLAAPGPGRRRRGPGPLPGAGPPGHRDRPPRPAPGRAGCAGRAPAAAAGRPSAPGGTPRPPGSARRGTRRRARSPPPSAPPEPPRA",
        "response#3": "MTTPRTPRPAAPPITRKPTRAPTAARARTRAATPRARTAAARPAAPHRAPAAARTGAHRTAAPRTRARQPPPRTTPTARTTPTTPTAPTTTPRTTRATAPRAPPTTRTRTARAPRTRARPTPRATTPRPPTAGPPRAHTRRAAPAAAPPHATPAAPRAAATPPPPAPTPSRAAAAPRAAPRPPHTVAPTTAAARTRTTRTRTAPRTRTTPRTTTPRTTRSTARTAHCPAPARRRTAAPAPGAPPRRRTPRAPRRTTAPRTAPAPPRTRPRTTAPRRPRTPRTSRTRATAAATAARTRATTRTPRRPTTTTPAPNTAPRTRTRTARTRAGR"
    },
    {
        "reference": "MLFQDLSFPAAVGAAFGAFAIYVVARCIYDLFFHPLRNFPGPKRAAIWSFYEFYYDVIKDGTYLWEIEKMHQRYGPIVRINSRSLHIHDPEYFSTIYAGSGRKVNKELSAVSGYTFPHSTISTLEHDLHRKRRAIVNPYFSKRAIADVEPVIHERLDTLISRLAEAKGNTVDLTCAFSAFTADVVTYHFYGSHANYIGSKDFKYGLKDALTVLLNLYNLTRFLPVPPTTIKNLPLPILGLINPNFPLVVSAREANKKMVLNYLDKPDEEKKAMKDARSKSVIVSALADSNVPDEEKTLDRLLDEGETIIFAGIDTTARTLAVALFHLLNNQDVLMKLRKELQTIAKSDGQQWTTTELEAVPYMRGVVQEAIRLAYGLVVRIPRISPHEALQYNGFVIPPGTPVSQSTYLVNNDASVFPNPQVFDPERWVKAAQDGTNLDKYMVSFSKGSRACLGINLAYAKLYLGIARVATSLDMELFETTRADIGVYHTRGFAFPKEGDGSVKARVRGLCK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450, Cytochrome_P450_monoxygenase, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 506
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 382
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 300,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 475
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 452
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 406,
                "End": 430
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 445,
                "End": 454
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 497
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 478
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 476
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 328
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 463
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 443,
                "End": 452
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 365,
                "End": 376
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 506
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 382
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 300,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 475
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 452
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 406,
                "End": 430
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 445,
                "End": 454
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 497
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 478
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 476
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 328
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 452,
                "End": 463
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 443,
                "End": 452
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 365,
                "End": 376
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21,
            31
        ],
        "response#1": "MKWFNFTTFDIMGDLAFGEPFGCLENSEYHEWVAIIFSSLKSAAFFDVVKRYPFLDTLARILMPKSLLEKRKKHLALTQEKVERRLAAGATDRPDFMTYMIRHNDEKTGMTNDELRANASLLIIAGSETTATLLSGATYLLTKHPDVMRKVTTEVRSAFKTEDEIVTGTKLASLTYLQATVEEGLRMYPPVPGGLPRVVPKEGATIDGHWVPGGTTVSVPQYAAYHSKANFGEDADEFRPERWLEATPEEKAKFANDKRDALQPFSAGPRNCIGKNLAYHEMRLILAKMLWHFDLELCPESKDWMNQKAYILWDKNPLMVKLTPVKRKEDW",
        "response#2": "MEHRTFTEAQVQKRLADKSKNADRKDLMDAFTNAKDEKGNSLTAEEISANASTLIVAGSETTATLLSGVTYFLLRNPECMKKLTEEVRSTFKSEEEIKLGSKLNSCKYLLAVLEEGLRMYPPVPIGLPRVTPEGAVVGGQWVPGGTEVSVSQWAAYHSEANFKDAEKFIPERWLGDERFKNDKREASQPFSIGPRNCIGKNLAYSEMRLILAKLVYNFDWELCPEADWTKQKSYVLWDKMPLMVKFTKR",
        "response#3": "MNDLMANASLLIVAGSETTATLLSGTTYYLLKHPETYQKVKDEIRTKFKDEDEIKTGATINSLPYLQAVIDESLRMYPPVPGGLPRLVPKGGATIAGEWVPEGTVVSVAQYAAARSKSAYFGEDADEFRPERWLGDERFKNDKRDASQPFSIGPRNCIGKNLAYHEMRLILAKMLWHFDLELTEESKDWLNQKNYMLWDKPPLMVRLKKVVR"
    },
    {
        "reference": "MGASTFSQSFAEKYEAWASVMLPALVGFAFLIYQAFFAIKYPANLPLAGEPDGKRTFSWRTRWRYYTDCEALYKETYENYTKRGKTVLLPGLGFRHDIILPQSSMRDIMAHPEKELSHADAVLELVQLKYSLGHEKYKADPWPCMLVKSDINSKLEAVCDGMNEELKYAFDKYIGCDTESWKEIDLLETIRMVIIAAASRFTVGFPLCRNEAYLRACWKVNDGIMMNGGLTGATPRLLRPIFGPLITMNLRRNIEKIKKQVEPVYCQRVQALSQQNSAEKPDSEEPKDLFQQMLRYAQKERPRELHDLPSMSRRLAFANFAAVHQTTILVTNMILNIVSSDSQYNTISVLRDEVNDIIGPDSNTKWTKYKVAQMIKSDSVARETMRLHSNTNRGVFRKVLVEGIKTEDGIELPKGAYVSFLGRPLQCNPETFEDPFKYDPFRFSRVREKAPRDAKATSNLSFVSTSPEHLPFGHGGHSCPGRFLVDFEVKMIVAYLLMNYDVEFPAEYNGQRPASRWMAEALMPPSGARIRIKRRS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 152,
                "End": 535
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 374,
                "End": 390
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 463,
                "End": 479
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 444
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 479,
                "End": 497
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 54,
                "End": 536
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 529
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 472,
                "End": 481
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 152,
                "End": 535
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 374,
                "End": 390
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 463,
                "End": 479
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 444
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 479,
                "End": 497
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 54,
                "End": 536
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 529
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 472,
                "End": 481
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21,
            22
        ],
        "response#1": "MHVASDAISAAEELRIYPEFLRPIVHWFLPSCKKLRKQLAEAREIINPVLEERRRQKEAAGDASLKRYNDTIEWFEETARGREYDPVLAQLSLSVAAIHTTSDLLSQVLFDLCARPELIQPLREEIIRVLRENGGLKKTAIYNLKLMDSVLKESQRLKPGIVAMKRMATKDITLSDGTFIPKGTKIAVSAHAMWDSSYPDPLTFDGYRFVKMREKPGQENSAQFVSTSPDHLGFGHGKHACPGRFFAANEAKVALCHILLKYDFKLVEGAKPEIANRGIFAVADPSAKIMVKRRKEEI",
        "response#2": "MFVGNDIHTDVVRTKLTRALGNITEPLSEETSYALKKNWTDNKEWHEINLHETVLRLVAQLSSRVFLGPELCRNDEWLNITKNYTVNAFLASTEALRLWPEFLRPIVHWFLPSCRKLREQLAKAREIINPVLEERRRIQEEAQAEGRTPTYNDTIEWFEEVAKGRKYDPAVAQLSLSVAAIHTTSDLLSQVLFDLCARPELIQPLREEIIGVLKENGWKKTALYNLKLMDSVLKESQRLKPVAIVGMRRMAMEDVTLSDGTFIPKGTQVTVSAHKMWDPDVYPDPETFDGYRFVRMREEPGKENSAQLVSTSPDHLGFGLGKHACPGRFFAANEAKIALCHILLKYDIKLVDGAKPKAVNTGFFLNADPSAKVMVKRREEEI",
        "response#3": "MKQLTKALSNITERLSEESSLALKKEWTDNKEWHEVNPQETILRLVARLSSRVFLGDELCRNEKWLKITTDYTVNAFTAAEELRLWPEFLRPIVHYFLPSCRKLRRQLAEAREIINPVLEKRRREKEAAAAEAKAEGQEPKERVYNDTIEWFEEVANGRSYDPAVAQLSLSVAAIHTTSDLLTQVLFDLCARPELIQPLREEIISVIREHGWKKTAIYHLKLMDSVLKESQRLKPVALVGMRRLAMEDVTLSDGTFIPKGTKVAVSAYPMWRDAENYPDPDTFDGYRFVRMREVPGQDSAQLVSTSPDHLGFGLGKHACPGRFFAANEVKIALCHILLKYDIKLADGAKPKMMNAGFFVNSDSSARIMVRRRKE"
    },
    {
        "reference": "MLQPSAQGSYSKAVLSTFRSLEDLTCDGSKIILDGQSLNVSSVVAAACHQVPASISKDPQLHARLRESVELLARKLAEGEIVYGVNTGFGGSADTRTDDYSTLQQALVQHQASGVLLPTDRSSSRPSSRYPHGLRSHSMPTAVVKAAMLVRCNSLLRGHSAVRPEVIEHILAFLRSGLIPVVPVRGSISASGDLSPLSYIANALEGNPDIAIQNEATGDVIRADEALQQLGLAPLRFGPKEGLGLLNGTAFSAGAASLVLFEANQLVLLSQVLTAMGTEALAGSTGNYHPFIAGVRPHRGQIEAAGNIFHFLRDSRMATSPGADGASHSSSLAQDRYALRTASQWIGPQIEDMSLASEQVHCELNSTTDNPLLDPGSGHMHHGGNFQATSITSAMEKTMSAMQMLGRMIFSQCTELINPALNNGLPPNLSFDDPSLSFTMKGIDINMSAYMAELSYLNHHVSNHVQSAEMHNQGLNSLALVASRYAAETVEVLSLMASAYLYALCQALDLRACHLEFLRNARSTVDSLTAELCLSFSPLLSESDQRQIQDSTWEQLLHHWNRSSTSDLHDRSRNAASHTMGALVELLPMQLNEATALPTRLAPQQQWLDEVSATLAGSYDATRAKFQSNPTTPFYLCSASRRMYEFVRKGLGVPLHRGIVDHPTYPSVTEEHAGQELIGSQVSKIYMALRGGVFRDVLQDCWYSSDSVRGFAGEELVLASKL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Aromatic_Lyase, Aromatic_Lyase, Aromatic_Lyase that shares evolutionary origin and functional similarity; 2. The protein should be classified within Fumarase/histidase_N, L-Aspartase-like sharing conserved structural features; 3. The protein must have Phe/His_NH3-lyase_AS that is conserved among related catalytic enzymes; 4. The protein must be able to perform the lyase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016841",
                "GO-Name": "ammonia-lyase activity "
            }
        ],
        "go_f_mapped": [
            32
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001106",
                "InterPro-Name": "Aromatic_Lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 511
            },
            {
                "InterPro-ID": "IPR024083",
                "InterPro-Name": "Fumarase/histidase_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 248
            },
            {
                "InterPro-ID": "IPR022313",
                "InterPro-Name": "Phe/His_NH3-lyase_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 186,
                "End": 201
            },
            {
                "InterPro-ID": "IPR008948",
                "InterPro-Name": "L-Aspartase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 704
            },
            {
                "InterPro-ID": "IPR001106",
                "InterPro-Name": "Aromatic_Lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 38,
                "End": 512
            },
            {
                "InterPro-ID": "IPR001106",
                "InterPro-Name": "Aromatic_Lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 30,
                "End": 704
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001106",
                "InterPro-Name": "Aromatic_Lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 511
            },
            {
                "InterPro-ID": "IPR024083",
                "InterPro-Name": "Fumarase/histidase_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 248
            },
            {
                "InterPro-ID": "IPR005922",
                "InterPro-Name": "Phe_NH3-lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 27,
                "End": 701
            },
            {
                "InterPro-ID": "IPR022313",
                "InterPro-Name": "Phe/His_NH3-lyase_AS",
                "InterPro-Type": "ACTIVE_SITE",
                "Beg": 186,
                "End": 201
            },
            {
                "InterPro-ID": "IPR008948",
                "InterPro-Name": "L-Aspartase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 704
            },
            {
                "InterPro-ID": "IPR001106",
                "InterPro-Name": "Aromatic_Lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 38,
                "End": 512
            },
            {
                "InterPro-ID": "IPR001106",
                "InterPro-Name": "Aromatic_Lyase",
                "InterPro-Type": "FAMILY",
                "Beg": 30,
                "End": 704
            },
            {
                "InterPro-ID": "IPR023144",
                "InterPro-Name": "Phe_NH3-lyase_shielding_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 514,
                "End": 634
            }
        ],
        "ipr_mapped": [
            577,
            129,
            133,
            575
        ],
        "response#1": "MENKEKPDKKEEENKKEKEKEENNNNKEKKEKEEIEKEIIKENEIEKEENNNKEKENKKKEENNIINNNDKNIKENSKEKNNENEIIESIIKDNNNIEKEKEKEEKKNINNENNKNDKKNNESIKIENTKIENIKNENIKNESINIEKDIKKEKISKEKILNEKIKIENKEIKENKEDINNKKNIDNIIKEEDIKKENINIENKEENIVEKDKILEKTNIKEKENNIKDNNIEKNENKEEINKEKEIEIEIKENIKKNKNIDIEKEIYNIEILKSSILYGLFSNDELCVNVYNIENESIY",
        "response#2": "AAAAAAPAAAAPAPAPAAAPAAAPAPAPAPAPAPAPAPAPAPPPPPAPAACAPPAPPAPPAAPAPAAPPPPAPAPPAAAPPPRRAPRRRRPPPRRRRPPGRRARPRRPPRPRRPPPPPRRRRGRRARGRRRRRRRRRRRRRRGRRGGGGGGGGGGRGGGGGDDGGGGGGGGAGGGGGGRGGGGGGGGGAGGAAGGGGGGGGGGGGGGGGGGGGGGAAAAAAAAAAPPPPAPAAPPPPAAAPAAAPAPAPAPAAAAGGGGGGDGGGGGGGAAAAAAAGGGGGGGGGHRRRARPRGPRPPPPPGRPPPPPRRGPHGGRGRGGQRRRPRARQQPRRQPRHQHQRRRRHQRHQHQRHQRRRHRRRRRRRRRHQQQQQQQQQQQQQRRQRRRRRRRHGGG",
        "response#3": "HHHHHHHHHHHHHHHHHHHHPPPPPPHHHHHHHHHHHHHHHRRRRRRRRRRRPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE"
    },
    {
        "reference": "MGLLLKMKMQNQHHPLASKLQEQTGNKRYTFIQAHRAWLLKLMFLWILLMALISRIIYSKMDVGTKVRRKEVLGSLCDQRARMLQDQFSVSVNHVHALAILVSTFHYYRNPSAIDQETFAEYTARTAFERPLLSGVAYAQRVVNSEREQFEKQHGVVIKTMEREASPVRDEYAPVIFAQETVSYLESIDMMSGEEDRENIMRARATGKAVLTSPFRLLGSHHLGVVLTFPVYKSKLPPNPTTEELIKATAGYVGGSFDVESLVENLLGQLAGHQAILVNVYDVTNSSDPLIMYGNQYEEGDVSLVHESKLDFGDPYRKHQMICRYHQKAPPNWTALSTAILFFVILLLIGYILYGAGNHIVKVEDDFHEMQELKVRAEAADVAKSQFLATVSHEIRTPMNGILGMLGLLLRTELNSTQRDYAQTAQACGKALIALINEVLDRAKIEAGKLELEAVPFDLRSILDDVLSLFSEKSRHKGLELAVFVSDKVPDIVMGDPGRFRQIVTNLVGNSVKFTERGHIFVKVHLSENRKPVTNGKHETYRNGGSEEVVHASGGYNLKTLSGYEAADERNNWDNFNHLIADEEFFCDASTKKVASNEFYEQVTLMVCVEDTGIGIPFSAQDRIFMPFVQADSSTSRNYGGTGIGLSISKCLVELMGGQINFISRPQVGSTFSFTADFGIFKKNPITEVKKVNYEDLPSSFRGLKAVVVDGKPVRAAVTRYHLKRLGIQVKVANAINKAVSLCGKNGASSTGLFQPDIIFVEKDSWVCGEDGIFSVRQLDWKQNGHIFKMPQMILLATNISNDEFDKAKSAGFSDTVIMKPLRASMVGACLQQVLGTGKKRQLGKEMPNGSTSVRSLLFGKKILVVDDNVVNRRVAAGALKNFGADVKCADSGKAALEMLQFPHKFDACFMDIQMPEMDGFEATRRIREMERTANEETNSECGERKSEFHLPILAMTADVIHATYEECLKCGMDGYVSKPFEEENLYQAVAKFFQTKPTSVDS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Sig_transdc_resp-reg_receiver, Sig_transdc_resp-reg_receiver, Sig_transdc_resp-reg_receiver, Sig_transdc_resp-reg_receiver that are essential for its biological function; 2. The protein should be classified within CheY-like_superfamily, CheY-like_superfamily sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0000155",
                "GO-Name": " phosphorelay sensor kinase activity "
            }
        ],
        "go_f_mapped": [
            19,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 861,
                "End": 990
            },
            {
                "InterPro-ID": "IPR011006",
                "InterPro-Name": "CheY-like_superfamily",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 860,
                "End": 995
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 862,
                "End": 994
            },
            {
                "InterPro-ID": "IPR011006",
                "InterPro-Name": "CheY-like_superfamily",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 701,
                "End": 836
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 705,
                "End": 835
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 863,
                "End": 990
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR042240",
                "InterPro-Name": "CHASE_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 114,
                "End": 329
            },
            {
                "InterPro-ID": "IPR036097",
                "InterPro-Name": "HisK_dim/P_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 369,
                "End": 449
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 861,
                "End": 990
            },
            {
                "InterPro-ID": "IPR006189",
                "InterPro-Name": "CHASE_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 110,
                "End": 322
            },
            {
                "InterPro-ID": "IPR036890",
                "InterPro-Name": "HATPase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 447,
                "End": 683
            },
            {
                "InterPro-ID": "IPR003661",
                "InterPro-Name": "HisK_dim/P_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 383,
                "End": 444
            },
            {
                "InterPro-ID": "IPR005467",
                "InterPro-Name": "His_kinase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 390,
                "End": 680
            },
            {
                "InterPro-ID": "IPR003594",
                "InterPro-Name": "HATPase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 495,
                "End": 680
            },
            {
                "InterPro-ID": "IPR036890",
                "InterPro-Name": "HATPase_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 437,
                "End": 675
            },
            {
                "InterPro-ID": "IPR003594",
                "InterPro-Name": "HATPase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 603,
                "End": 678
            },
            {
                "InterPro-ID": "IPR006189",
                "InterPro-Name": "CHASE_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 110,
                "End": 295
            },
            {
                "InterPro-ID": "IPR056839",
                "InterPro-Name": "Receiver_AHK4/CRE1_1st",
                "InterPro-Type": "DOMAIN",
                "Beg": 698,
                "End": 836
            },
            {
                "InterPro-ID": "IPR050956",
                "InterPro-Name": "2C_system_His_kinase",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 991
            },
            {
                "InterPro-ID": "IPR011006",
                "InterPro-Name": "CheY-like_superfamily",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 860,
                "End": 995
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 862,
                "End": 994
            },
            {
                "InterPro-ID": "IPR004358",
                "InterPro-Name": "Sig_transdc_His_kin-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 640,
                "End": 658
            },
            {
                "InterPro-ID": "IPR004358",
                "InterPro-Name": "Sig_transdc_His_kin-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 605,
                "End": 619
            },
            {
                "InterPro-ID": "IPR004358",
                "InterPro-Name": "Sig_transdc_His_kin-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 664,
                "End": 677
            },
            {
                "InterPro-ID": "IPR004358",
                "InterPro-Name": "Sig_transdc_His_kin-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 623,
                "End": 633
            },
            {
                "InterPro-ID": "IPR003661",
                "InterPro-Name": "HisK_dim/P_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 383,
                "End": 448
            },
            {
                "InterPro-ID": "IPR011006",
                "InterPro-Name": "CheY-like_superfamily",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 701,
                "End": 836
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 705,
                "End": 835
            },
            {
                "InterPro-ID": "IPR006189",
                "InterPro-Name": "CHASE_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 113,
                "End": 293
            },
            {
                "InterPro-ID": "IPR001789",
                "InterPro-Name": "Sig_transdc_resp-reg_receiver",
                "InterPro-Type": "DOMAIN",
                "Beg": 863,
                "End": 990
            }
        ],
        "ipr_mapped": [
            225,
            223
        ],
        "response#1": "MSHRLPEPHARQQQGQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPTTTTTTTTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNRYLR",
        "response#2": "HHHHHHHHHHHHHHHHHHHAAAAAAAAAAAAAAAAAAAAAAAAHHHHHHHHHHHHHHHHHHHHTHTHTHTHTHTHTHTHDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDEDEDEDEDEDEDEDDDDDDDDDDDDPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAPPPPPPPPPPVAAAAAAAAAAAAAGAAAAAAAAAAAAAAAAATTTTTTTTTTTTTTTTTTTTTTTTTTTITTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT",
        "response#3": "MKYFEQDKQFENKITVDNYKLSSEKIITNINIDSKDESIISNKDIEKYTDINIIQDNKKLEYSNVIIKEDKYIDNKLNKDIINKIEINKINNKDIENIDIDKDIIINIKNNKENKYIDIINYKDKDIDSNKINIIKSYNKSIDKIKNFNKANIKDKINKKSKINKINEDKKYILNKKNNKIIGNIKNKINESKDNNNIDIIDNNNSDIDNNNSKDIDNIDNKDSIDDIDTDIDNIDNKDDINKDIDDINKDIDSDNKIDNIDNIDDKDDIDNINKDNKSKIDNIDIIDDSIDKKDDIESNKSSKDDKDSDKYKSDIESKSDKDDNKSKIDNINKDIDIDNKINNIDKNKDDNIDINKDIESSKDINIDNNNKDSIDDNNKDIDINKNNIDNNKE"
    },
    {
        "reference": "MASENNKRKASEEALSPDSQLQSKKARTDSPEREPKSEGGPLGKPPLRIVPFPEKPAVLEERRGEIEFRVVNNDGSRDSFVVLTGLKCIFQKQLPKMPKDYIARLVYDRSHLSIAIVKHPLEVVGGITYRPFNSRRFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATSPIMHFLTYADNYAIGYFKKQGFTKEITLDKSIWMGYIKDYEGGTIMQCTMLPKIRYLEIGRMLLKQKEAVHAKIRAFSRSHIIHAPPKEWKNGACKIDPLSIPAIKQSGWSPDMDELARQPRHGPNYNQLLHLLNDMQNHSAAWPFTQPVNRDEVPDYYEVIKEPMDLSTMEEKHEKDMYPTPQDFIKDAMLIFDNCRRYNNENTPYAKSANKLEKFMWQQIRNIPEWSVST",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Acyl_CoA_acyltransferase sharing conserved structural features; 2. The protein must be able to perform the N-acyltransferase activity,N-acyltransferase activity,N-acyltransferase activity,N-acyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            },
            {
                "GO-ID": "GO:0016410",
                "GO-Name": "N-acyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0140068",
                "GO-Name": "histone crotonyltransferase activity "
            },
            {
                "GO-ID": "GO:0036408",
                "GO-Name": " histone H3K14 acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0043993",
                "GO-Name": " histone H3K18 acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0043992",
                "GO-Name": " histone H3K9 acetyltransferase activity "
            },
            {
                "GO-ID": "GO:0140566",
                "GO-Name": " histone reader activity "
            },
            {
                "GO-ID": "GO:0070577",
                "GO-Name": " lysine-acetylated histone binding "
            },
            {
                "GO-ID": "GO:0003712",
                "GO-Name": " transcription coregulator activity "
            }
        ],
        "go_f_mapped": [
            238,
            238,
            238,
            238
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 88,
                "End": 226
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018359",
                "InterPro-Name": "Bromodomain_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 313,
                "End": 370
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 308,
                "End": 378
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 105,
                "End": 192
            },
            {
                "InterPro-ID": "IPR037800",
                "InterPro-Name": "GCN5",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 397
            },
            {
                "InterPro-ID": "IPR000182",
                "InterPro-Name": "GNAT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 66,
                "End": 221
            },
            {
                "InterPro-ID": "IPR036427",
                "InterPro-Name": "Bromodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 284,
                "End": 401
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 301,
                "End": 383
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 289,
                "End": 397
            },
            {
                "InterPro-ID": "IPR016181",
                "InterPro-Name": "Acyl_CoA_acyltransferase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 88,
                "End": 226
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 311,
                "End": 324
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 359,
                "End": 378
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 341,
                "End": 359
            },
            {
                "InterPro-ID": "IPR001487",
                "InterPro-Name": "Bromodomain",
                "InterPro-Type": "DOMAIN",
                "Beg": 325,
                "End": 341
            },
            {
                "InterPro-ID": "IPR036427",
                "InterPro-Name": "Bromodomain-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 276,
                "End": 399
            }
        ],
        "ipr_mapped": [
            162
        ],
        "response#1": "MSVTLAELAARLGGEVAGDAQCAVTGLAPLAEAGPEQLAFLANPKYLAQLAQSRAGAVLIAPKDRAAAEASGIALIVTPDPYAYFARIAQLLDPAAARAGGIHPRATVDPDARVGPRCTLGPHVTVGARAEIGEDTVIGAHTGIGADTRIGRRCQIGARAGIAARLTLGDGVIIGAAAGVAADIPAGRIWSGSPARPIADWLREAARLRD",
        "response#2": "MASVTLAELVARLGGRLAGDAACEVGGLAPLGEAGPQDIAFLANPKYAAALAETRAGAVLIAPADAARFAGTAIVCRDPYLYFARVADLFDPKAARGDAVPHVGGVTVAAGAHIGANGAIAPGAIGDTVIEEGVKIDNLVQIGHNCRIGRRTAIAAQAGIAGHTTIGDDCAIGGQAGIAGHVTIGDRVQIAAQAGVSNDIPAGERWGGIPARPIADFFRDVAALRPAVRGGAPRRAPQSDAE",
        "response#3": "MATLTLDELVARFGGEIAGDGACRVGGLAPLDQAGPQQLAFLANPKYLSQVETSGAGAVLIAPKDAEKVAALLAAGPGGAPAPRPFIVTPNPYLAFARLAQFFIDLARAPRGAAPADGAGAAPGVHPSATIAPTAIVDPAAQIDAGVTVGPHATIGAGTRIGAGTHVAAGAVIGPHVEIGADGVIWAGATIYHGCKIGARAIIHSGAVIGSDGFGFAPDAKGDWVKIPQVGGVTIGDDVEIGANTAIDRGAMQDTVIEDGVKIDNLVQIGHNVRIGAHTVIAASAGIAGSTTIGRHCMIGGGAGIAGHVDIGDYVIVTAKSGVSKSLPKAGIYTSAFPAQPHADWNRSAALVRNLDKLRDRIKALETALAARGGADAAPSASGEPGAP"
    },
    {
        "reference": "MTVNLTELDAHEQPSDQMRAIWKSYSRADKEELLLNGAIDDLEKPEKAAEFVVAGTVPAATLTKGFAFLGSGFDAAASDAPIYYHPLLPGLLIFPSIVPLEVQKTLLSKLIHRDLSVPAHQTNMHLHYELPYVERKPTDGEGEPEDCRQSFFSHSPDSPVRFQPKDPDVHKPLSMKQVMDRRLHWVTLGGQYDWTNRVYPEEEPPKFPPDVAGFLETVFPDTIAQAAIVNFYTPGDTMMMHRDVSEETDKGLVSLSLGCDGLFMIAPSDIGKMSEEERPEDVKKQYLLLRLRSGDAIYMIKESRYAWHGVPKVLKGTCPEALEDWPAEDGRFEEWRGWMKNKRINLNVRQMRE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Oxoglu/Fe-dep_dioxygenase_dom that are essential for its biological function; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051213",
                "GO-Name": "dioxygenase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 222,
                "End": 352
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 222,
                "End": 352
            },
            {
                "InterPro-ID": "IPR004574",
                "InterPro-Name": "Alkb",
                "InterPro-Type": "FAMILY",
                "Beg": 78,
                "End": 351
            },
            {
                "InterPro-ID": "IPR027450",
                "InterPro-Name": "AlkB-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 159,
                "End": 349
            },
            {
                "InterPro-ID": "IPR037151",
                "InterPro-Name": "AlkB-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 149,
                "End": 352
            }
        ],
        "ipr_mapped": [
            871
        ],
        "response#1": "MGKKKKKNEEKENKDKNEEKENENKEENNEEEKEKNEKEEKEKEENKEGEENKEEKNKEEEEKIKEEKKEKNEEKKKNKKKSKKKKNQEENNNEEEKENKEEKIEEETNNNNNEIEDNINEEKNINNNNNNKNKNKKNNNSKEENVKEEEENIIEEENINKEEKNKKNKNKNNNNKKKKKNKENNKKKNQNKEEQNNLQQQQEQNIQQQEQEQQQQNQQEQQQQQQQQEQQQQQQQQQNNQQQQQQQCNNSQNNNEQQNNQEEIKSFPQKKKKNKTKKNNNDSNRFASRHSNRIRTAVLFTGSLIFK",
        "response#2": "MNNYFLFKKILNKNEINKCKNYILNNKNLWKNSLVGGKKNYNKNIRNNFQIKINKKNKFYLKLEKKILIKLNPKILKNKYISFIFPKKINNLLFTKSNKNGFYKKHIDNAYFFNNQRSDLSFTLFLNNIDKYKGGELILYENNDEKKVILNKGDLLIFPSYKFHEVNKVKKGERLSLVGWVQSIIKDNNKRNFLFNLDKEIKMLKKNLNKKNKNYLKIKNKYNKIMKNYFLLLNEIKKI",
        "response#3": "MRTRRASARGRAPRRRAFTLIELLVVVAILAILIGLLLFALRSARDAARRAQCLSNLKQVGTALLLYANDNDDRLPVAASGTPIRWADALVGPYLKDATVLRCPADRSSTLTNYGVNRNLIPPPPGAPGARLNRVSYGMNLDASAAGAPGWMGEPIPSALRLADVRQPSSTPLFADSNPTAVTWLACPGADPANPGNPDGANVLYLDGHAAFERGTPSASATSPPTPPPSPPPPPPSPSPPPPPPPPPVQPAPPPPAPPSPPPAPQPAPP"
    },
    {
        "reference": "MHLHYDLPYPKHDMTDEPVSFFTYPPDSDTKFIPKDPCVHKPLSIKQVMERKLHWITLGGQYDWTNRVYPGERPPEFPRDVAGLLETLFPETLAQAAIVNFYTPGDTMMMHRDVSEETDKGLVSLSMGCDALFMIAPNDVGKMSEEDRPGHGEKEHLLLRIRSGDAIYMTQEARYAWHGVPKVLKGTCPDYLEDWPAEDGKYEEWQGWMKNKRINLNVRQMRDC",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Oxoglu/Fe-dep_dioxygenase_dom that are essential for its biological function; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051213",
                "GO-Name": "dioxygenase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 93,
                "End": 222
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR004574",
                "InterPro-Name": "Alkb",
                "InterPro-Type": "FAMILY",
                "Beg": 47,
                "End": 221
            },
            {
                "InterPro-ID": "IPR037151",
                "InterPro-Name": "AlkB-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 223
            },
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 93,
                "End": 222
            },
            {
                "InterPro-ID": "IPR027450",
                "InterPro-Name": "AlkB-like",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 219
            }
        ],
        "ipr_mapped": [
            871
        ],
        "response#1": "MATPPTAAPAPPPSGPPAPRRAPTDRPGTPPGRAATPSPPPAAGRPSRPGTTRTGAAPSAARAHRTAHTAHRTAHPTAHRTAHPAAQPSHRAARPSSAPGSAPRPAGSAAPPPPCASPGPAAPGRRPAARRRTAAAAAPPGARTGRARPGRARPGRARPGDRDRRARPRTAALPSAHAAARTARPSGRARRPSRRTGSPGPPRRTRGVPRAARTGTAPGPGTARARPPGRARRAPARATRRDASSPGRRSPGAARHGWRAGSAGPGRRAPSSPPGARRGAAPRQDACGRVLRPARPPRRPAAPPRPARPATASAPGTAPRTARRRGRRPARPAPSSPSPPPPRSTAPPRSTAPARGAAPPAGPARTRP",
        "response#2": "MDTLPAAPAPPTPPTPAAPPTPAAPPTPATPPTPAAAPPTPAAAPAAPTPAAAPAATPAAAPAAAPTAAPTAAPTAALTPAPTPAPTPPPPAPPAPVPGYRLDRPLGRGSWSTVHRAHRPDGTPVAVKTALLPPGTPPGERRRRTERFARQARLLAGLRHPRLVRLLDHGTAPDGTPYLVTEYVPGPTLAHRLRAAHPERLPLPEVLRIAADLADALAFLHARGVVHGDVKPENVVLRTGPATGAVLIDLDTAHPAGTDLPATLTPSGTPAYLPPDRTEGAPTTPAADVYALGATLHHALTGRPPPHGDRRPAAPPPPAAPDAPPALRDLLAACLDPDPRRRPTAADLAARLRAAAAPPAPPAPPERH",
        "response#3": "MKKTVLVTGGSGFIGSHIVDYFLKENYHVYATSRQPKQNFKHPNLTYIQCDITNAEDVEKLIQKVSKIDTVVHTAGVMPFFGITKENIEQCYKVNVTGTLNLLKALEKTNINKFIYVSSAAVYGEPSTKPITEETDVQVLYQRYMDMSIEEKLKHIQEIIKEEYKGKFLTEEYKKTYEEKVTNLYEIMKNTKDVQFENNNHINSYKITGIKSFLEKLLKNFFKIIQQIFLQNVKKNVKK"
    },
    {
        "reference": "MAAVTRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAGGRALEQELSGTVFIPGDVTQERDLQTLVSETLSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEVNLLGTYTLIKLALPHLRKSRGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWEELAASTSDPRATILEGTLAQPLGRMGQPAEVAAAAVFLASEATFCTGLELLVTGGAELGYGRKASKSSLGEVPTLPPNVH",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Sc_DH/Rdtase_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity,identical protein binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": "identical protein binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0047834",
                "GO-Name": "D-threo-aldose 1-dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": " identical protein binding "
            }
        ],
        "go_f_mapped": [
            4,
            27
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 141,
                "End": 169
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 249
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 249
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 128,
                "End": 144
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 173
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 192
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 81,
                "End": 92
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 214,
                "End": 234
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 134,
                "End": 142
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 141,
                "End": 169
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 249
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 249
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 128,
                "End": 144
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 154,
                "End": 173
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 192
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 81,
                "End": 92
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 214,
                "End": 234
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 134,
                "End": 142
            }
        ],
        "ipr_mapped": [
            8,
            9,
            7
        ],
        "response#1": "MARRLENKVAIITGGASGIGEATARLFHSEGAKVVIADIQDELGEKLEKELPDSIYVHCDVTKEDEVKKVVDTAVQKFGRLDYAFNNAGISQSMSPITDSTVEDFDKVQAINQRGVFLCMKHEIKQMLKQGRGSIVNTSSICGITPNSAYLSMVPEENFQKMKEQTPLGRIGKPEEIAYAALYLASDESSYVTGQNLVVDGGYTAG",
        "response#2": "MAKRVEGKVALITGGASGIGEATARLFLSEGAKVVIADIQDDLGKKLAESLSSEFGVDKAIFVHCDVTKEEEVKAAIEKAVNTFGKLDVCFNNAGVMTKAALEVMEKTGGGSIINASSVAGMVGIVAGPVYTATKHGVVGLTKNAAVDYAKKNIRINAVAPGMIETPLLHKAWETVPEAKKQLLERTPLGRIGKPEEVAYACLFLASDESSFTTGVVLPVDGGYTAQ",
        "response#3": "MPLRAPGPRPPPPLLLLHLPPPLLLPLAALFLARRRAVFRFSSVSPPPDAMARRLDKKVAIITGGASGIGEATARLFAKENAKVVIADLLDEKGQKVANEIGGIFVHVDVSKEADVEKMVKTAVDTFGRLDCAFNNAGIVDVFTAVPDTDVEEWDKVISVNLRGVFLCMKHEIKQMLKQEPGPDGSRGSIINAASVAGMVGVTSGHAYAASKHGVVGLTKSAALFYASRGIRVNGIAPGWIDTPMLDASFKAAGDPEPNRKFCETVHPLGRMGKPEEVAYAALYLASDESSFTTAAVLPVDGGYSAVSSYCVPYFV"
    },
    {
        "reference": "MNGREHRRGDEAARREARSILFQNQDRSIVLIDVPTSIEEAQASPEEVGCDAGPLRKRRRLISSEPPHLPFKTPEPKAGSGGLTESVSDLMIAAAATEALRVLQESYAGPFCLPRVTRPNPLKSAFVPKGSFFLHGTVSSERDRFAAEAPVFDLIVLDPPWPNRSARRKQRNYRVADSLGSIRETLSLIPIAAHLAPDGLLAVWITNKAGVVELLTGPRGLFAQWGLEQVDEWTWLKITTSGEPIVDVGSTWRKPWERILIARRRGSSRKPACRGRVLVSVPDLHSRKPNLRGLFEDVLVPSNKGLEIFARNLTAGWWSWGDEVLKFQQPEYWVES",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein should contain DNA_methylase_N6_adenine_CS that is preserved across related proteins; 3. The protein must be able to perform the methyltransferase activity,nucleic acid binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0003676",
                "GO-Name": "nucleic acid binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity "
            },
            {
                "GO-ID": "GO:0003676",
                "GO-Name": " nucleic acid binding "
            }
        ],
        "go_f_mapped": [
            20,
            116
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002052",
                "InterPro-Name": "DNA_methylase_N6_adenine_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 155,
                "End": 161
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 152,
                "End": 268
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002052",
                "InterPro-Name": "DNA_methylase_N6_adenine_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 155,
                "End": 161
            },
            {
                "InterPro-ID": "IPR007757",
                "InterPro-Name": "MT-A70-like",
                "InterPro-Type": "FAMILY",
                "Beg": 152,
                "End": 323
            },
            {
                "InterPro-ID": "IPR007757",
                "InterPro-Name": "MT-A70-like",
                "InterPro-Type": "FAMILY",
                "Beg": 111,
                "End": 336
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 152,
                "End": 268
            }
        ],
        "ipr_mapped": [
            964,
            70
        ],
        "response#1": "MTATTPYRPQPRPYTTDYTVDGQRWTVTSAPGVFSARGLDVGTRVLLDSLPAGITGRVLDLGCNAGVLAVTLAARDPRVQVDAVDIHPAAVEAARANAAASPVGDRVRVWQADVRDVAAELPLASFDLVISNPPFHDGIVTSLGAAQALIEAAARCLVVGGELRIVANRFLRYPDVLAEHFGEVTTIASDGRFVVHSGVKTERRPAPTAEQAAARAARARERARRR",
        "response#2": "MHEPTESAPAYDVDVARGDLVVVDWVIGLIADAAGDATGTEVRFSLVTDEPTGPFDRVLIQIPKAKPLLTEQLLRLSRLVAPGTRIVAVGENRSGIKSAEKVLAEYGLPTGTTLAWKRARLISATAGEQPPFPDSWPRSYTVTVDGREWTVTTLPGVFSRDGLDIGTRLLLDNLPADVTGRVLDLGCGNGVLATVAADRGAASVVAVDESAPAVEATRATLAANGLGDRAEVRMSSVLSGVTGRFDMVLSNPPFHDGIATSTHAAHELLVDARRCLVIGGELRVVANRHLAYPAVLDEVFGPCTTVASNNRFVVYSAVKTRQPRRG",
        "response#3": "MSASPARSYEVEVAGRTLTVHSLPGVFSAERLDVGTEVLLRSLPTDVRGRILDLGCGAGVVGVALAARSPQVQVTMVDSSHVAVESARASARLNGLDESRVRFVLSTDGLRGRFDLVVCNPPYAARLLPDLLVRAAECLVPAGRLVAVGLARSGVNSAEKLLAEYCGPTRTVAAAKKHRVLVAEFDKNPPRAGYAPRSVTYAVEDSPWTITTTAGVFSRDGLDVGSRVLIAALPSDLRGEIIDLGCGSGVLGVALAQRSPQARVTFVDESPMAVASARANFAANGLADRAEFLVNGVLSGIEPERFDMVICNPPFHDGIATSTHAAEQLLVDARRCLRIGGELRVVANRHLAYPHVLDKVFGNCTQVASNSKFVVYSAVKTARAPRG"
    },
    {
        "reference": "MYTLLDILKGLPLLAVAAIASADYPTIPSDLTTPVQQRLAISGMNSVSVGWNTYEKLLKPCVQYGTSSTDLSQETCSLISTTYNTSRTWSNTVILTDLTPATTYYYQIVSTNSTVNSFFSPRTPGDKSPFTTSVVIDLGVYGADGFTVDADGDPTRKVLIPEVEPALNHTTIGRLADTWDDYEWVLHPGDFGYADDWYLTPTNVGDGVNAYEAILENFYDQLAPIAGGKVYMASPGNHEADCEELGTPAIELSCPEGQKNFTDFNVRFGKNMPTSFSSTSSNTKAKVNANKAAALANPPFWYSFEYGMVHVTMIDTETDFPNAPDAPFGTAGLDGGPFGYTGQQLDFFEADLASVDRTVTPWLLVAGHRPWYSTGGQSNICSACKTAFEPLMYQYGVDLGVFGHVHNSQRFAPVNNSVVDPAGMDNPTAPMYIIAGGAGNIEGLSSVGNNISSNRFAYAETFSYATLTFEDENNLSIQFIESATGDILDSSTLYKAHTEQFVNQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Calcineurin-like_PHP_ApaH that are essential for its biological function; 2. The protein should be classified within Metallo-depent_PP-like, Metallo-depent_PP-like sharing conserved structural features; 3. The protein must be able to perform the hydrolase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003993",
                "GO-Name": "acid phosphatase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            19,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 181,
                "End": 479
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 164,
                "End": 503
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 181,
                "End": 407
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 181,
                "End": 479
            },
            {
                "InterPro-ID": "IPR039331",
                "InterPro-Name": "PPA-like",
                "InterPro-Type": "FAMILY",
                "Beg": 32,
                "End": 491
            },
            {
                "InterPro-ID": "IPR008963",
                "InterPro-Name": "Purple_acid_Pase-like_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 121
            },
            {
                "InterPro-ID": "IPR029052",
                "InterPro-Name": "Metallo-depent_PP-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 164,
                "End": 503
            },
            {
                "InterPro-ID": "IPR025733",
                "InterPro-Name": "Purple_acid_PPase_C_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 429,
                "End": 490
            },
            {
                "InterPro-ID": "IPR041792",
                "InterPro-Name": "MPP_PAP",
                "InterPro-Type": "DOMAIN",
                "Beg": 168,
                "End": 495
            },
            {
                "InterPro-ID": "IPR015914",
                "InterPro-Name": "Purple_acid_Pase_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 118
            },
            {
                "InterPro-ID": "IPR004843",
                "InterPro-Name": "Calcineurin-like_PHP_ApaH",
                "InterPro-Type": "DOMAIN",
                "Beg": 181,
                "End": 407
            }
        ],
        "ipr_mapped": [
            641,
            643
        ],
        "response#1": "MHKKKNNKIKYNKKNVNNINKNDIYKYKNKKIKHKKNYLKKQIYIKKNNKKQIKHNYKNNIYNNNIYNNNILYNKQKINKHKINNKIKINNNKNIYKKNKKKNKYIYKKYKYIYKINNYIYNICIYNYHYNYNIYILIKKYLYNYNNIYIYNKYIIYITNININIHIYDIKINHYNIHIYKYIYIYYNNIYFYINIYINK",
        "response#2": "MLPPPPPPPPPPPPPPPPPPPPPPPPPPPRRRRRRRRRRRRRRRRRRRVVVVVVVVVVVEEEEEEEEEEEEEERRRRRRRRRRRRRRRRRRRRERRRRRRRRRRRRRRRRRRRRRRRRRRRRRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPPPPPPPPPPPPPSSSSSSSSSSSSRRRRRRRRRRRRRRRRRTTTTTTTTTTTTTTTTTTTTTTTAAAAAAAAAAAAAAAATTTTTTTTTTTTAAAAAAAA",
        "response#3": "PGAARRAGFRRRAGRRAAGAGGAGVRAGGAGGAGVRAGAAGRRAGAAAGAAGRRGRAGAGRRARAAARAAGRRAGARPAGRRAGGRAGARAAGRAAGRAGGAGGRAGAGGGAGGGRRRGAGGGGRVRAARAGRPAPAPPPPPPPPPRPPARGPPPPPPPPSPPPPRPPPPPPPPPAPARAPRPPARAPAPPPRPADTRWRSAGRTGRTPGR"
    },
    {
        "reference": "MQPFGDAWSQRHLAGVVLAGSVLSIVGSLYMILGFFFLRECRSFRHKLILGLAVSDLLLALNFFIPSLSMVTGREISSPWNEGFCSANGFLMQLFFAQIDVWQISIALITLLMLSGPSMVLKWIRENVWAVWLFPWLVSLIAAFFAFGFWDYANVGGFCWLGSRNIRLYFNYIPRWIIILVCLVIYIAVYRLILHARRRANIQKTYRGRASDRAPPQPVTTTAPATNPESEKVNPDEISSGNGSSSLDTSRSGSSTGFTQTVHDPAVAGQIQTAAERAQEEAEQQKQVRKIAIQMISYPLAYAVLWAIPTIVMIIQVARGGEGVSIHVEGLAKMLLVFNGFVDAHVYGFNERTAMGWRQRIRPAAQEDDEEAAGTSGGVHEVVSRPEPTLKNPNVWQQNMV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein must be able to perform the G protein-coupled receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            }
        ],
        "go_f_mapped": [
            0
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 347
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR022596",
                "InterPro-Name": "GPR1_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 283,
                "End": 352
            },
            {
                "InterPro-ID": "IPR022343",
                "InterPro-Name": "GCR1-cAMP_receptor",
                "InterPro-Type": "FAMILY",
                "Beg": 85,
                "End": 103
            },
            {
                "InterPro-ID": "IPR022343",
                "InterPro-Name": "GCR1-cAMP_receptor",
                "InterPro-Type": "FAMILY",
                "Beg": 43,
                "End": 58
            },
            {
                "InterPro-ID": "IPR022343",
                "InterPro-Name": "GCR1-cAMP_receptor",
                "InterPro-Type": "FAMILY",
                "Beg": 24,
                "End": 42
            },
            {
                "InterPro-ID": "IPR022340",
                "InterPro-Name": "GPCR_GCR1_put",
                "InterPro-Type": "FAMILY",
                "Beg": 46,
                "End": 68
            },
            {
                "InterPro-ID": "IPR022340",
                "InterPro-Name": "GPCR_GCR1_put",
                "InterPro-Type": "FAMILY",
                "Beg": 30,
                "End": 44
            },
            {
                "InterPro-ID": "IPR022340",
                "InterPro-Name": "GPCR_GCR1_put",
                "InterPro-Type": "FAMILY",
                "Beg": 176,
                "End": 199
            },
            {
                "InterPro-ID": "IPR022340",
                "InterPro-Name": "GPCR_GCR1_put",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 28
            },
            {
                "InterPro-ID": "IPR017981",
                "InterPro-Name": "GPCR_2-like_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 13,
                "End": 198
            },
            {
                "InterPro-ID": "IPR023041",
                "InterPro-Name": "Glucose_rcpt_Git3_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 194
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 27,
                "End": 347
            }
        ],
        "ipr_mapped": [
            1
        ],
        "response#1": "MDSRLHTPMYFFLSNLSFLDICYSSVTVPKMLVNFLSENKTISFLGCMTQLYFFLALGGTECFLLAVMAYDRYVAICNPLRYTVIMSPRVCSLLVAGSWVGGTVNALVQTLLTMRLSFCGPNVIDHFFCDIPPLLKLSCTDTSVNELVVFVNSGFVEMFTFLLILISYVYIISTILKIRSTEGRHKAFSTCASHLTAVTLFYGTIIFMYVRPKSNYTPDQDKVVSVFYTVVTPMLNPLIYSLRNKDVKGALKKLMGRKCFSSEKTTL",
        "response#2": "YFFLSNLSFLDICYSSTTVPKMLVNFLSENKTISYSGCLTQLYFFHAFGGTECFLLAVMAYDRYVAICNPLRYTVIMSKRVCVLLAVASWVGGSLNALIHTLLTFSLTFCGSNKINHFFCDIPPLLKLARSDTHVNELVLFVDCGFVTLTSFLVIVTSYTFILSTILKIHSTEGRHKAFSTCASHLTAVTLFYGTIIFMYLRPKSYYSPDKDKVVSVFYTVVTPMLNPLIYSLRNKDVKGALKKLLSRRICSSHSL",
        "response#3": "MDSNFSVIMNNIISTFDNDSSFSYSQTVIIILSSVFASVFILTVIGNLLVILAVVLEKHLQTVTNYFIASLAVADMLVGTVVMPFSLYYEIRGYHWPFSDFLCNIWVALDVMFSTSSIIHLCVISVDRYIAITKPLKYPCIMTKKRVIKMITCTWVLSTIISLPPLIGWKLKDTIIVNITNITINTTTTTTTTTTTTTKYCEEVWPSQQQQKYYSIYTFVLTFLVPFIIMVVTYSKIYQIARKHASKIRVHTMSDDSSNIESKKKAIKMVIVVVMVFAICWLPLHVVNMWASFDRETYNQVPDVTFTFALMMGYVNSCLNPLIYTIFNDNFRKAFKRVLHCKSKFIYSSSSSTNRSKDTSL"
    },
    {
        "reference": "MDTMKRKHQGLFPVLNDGGREPSVTVNEISSEARERAIAYTARRGYDIVHFLRTVWSIVLQQFLETDLVCFVFFDHSGVQVCEVPVSREESIPNLLERIAELRPLPSALCEETRMNTGLLIGDTSLDVNPTAVLDTFRRIQKDNQPCDCLLVLEGEPPHRLALVATTTLLSSDQATAVASTVSQVMVEMSAEDNSRTVGDLSLLSEHDQQCLVRWNNFQAPPTNTDGSILDTIRAKALSQPEATAIHSPDVIMTYHELDTISNKLAVHLRLLGVRPDILVPFLFQRCHWVIVVQLAVLKAGGAFVPLEPAHPNARLAEITKRTNCGFLLTSDANAGRAALLAEKVVCINHSLMSSLPTDFTTYRLVPLSSPSSPAYVLFTSGSTGQPKGCVVDCRAMAQIPNQAVVQSMGLSSSTRVLQFASYTFAISIFEIYYALGSGATICMPTDHDRINSLATVMDEMKITWACMTPSLLRTLDPERSPATLKRVFLGGEPVVKGEFEAWAAIVDLVYVYGASEVSGAIGFTDHQCDGNDIAYRAFPGMRFWISDALDYHKLAPVGVTGELILEGPALAQRYLDDVQSTLTAFIDPPLWRQSLGLPTVGAASRMYKTGDLFRYAHDGSVIHVGRKGTQVKIRGKRLDLGEVEFHVSKCCPNVARVIAETAAPLDANGVPALVLFLYYSADDAGERNEETTPQTLFAAASERFQSIVQSTQTKLEQTLPDHMLPSFYLPLASIPMTVTGKVDRRALRESVQKCTRRELEAYQPTGVVELVPPETVLEKALHAVFAQVLRIDGATFGVHHSFIRLGGDSLAAMRAVGLLTTKEYNVTVADILGQPTVSKLAQYLRNTERPQRASAAASAPPPFSLLAGGHDETVASAAQQCGMSISAIEDCYPCTALQQGLMISTMRVPGRYIARCVFDLARGLDLERLKAAWQQTVDANVILRTRIVRRASGDLIQAVLGRQVSAIQWQSYPTVGAYKMEDAVIPMQPGDALARFALIGDTFSGWSLGLTLHHAIFDAHSLGLLLEQTQQAYYGANLDPNLFSPFIETVQKQDGASEREFWTATFADIHAPVFPSLPHDRAVPRASTHLERTIPLLSRTGSGITLSNVARLAWAIVVSAHTDSEDVVFGVTVNGRATATAGAQDMTGPTIATVPFPVRCQKQKKVADVLEAVQSLAISMMAFEQTGLQKIRQMSPQAAAACDFQSQLIFQRPAALDPSHQHDAPPIMVGKTALHGLEDFSVFIDYVIGAYFDGDILPGYMAERMMGQFANVLQQLCAGQHDRVVGELELNAQKEPLMPAVSSWDRGLTYRELDVLSATIAQTIIMPAGVKERDRVALCFEKSVWPVLSMLAVLRAGATAVNIDPTLPPARMSAILETGLPVIEISQTSVPMTTTTTEEAAQIQWPTVQPNDVAFILFTSGSTGTPKGIVIEHRHFTTAFHHHRDALLQEIFFTWVHGGCLCIPSEEQRLSNLAGFIREHQVNWAIMTPSASTILRPQSVPGLETLVLAGEPIPVELMELWSSRLRLLNGYGPAEAFTCAFNRIEPGSHHPGLFGPMCGVVGWVTVPDNADRLAALGAVGELLIEGPTVTRGYLDLPELSGEAFIDAPEWLRKIRPGYLGRKDTQVKQVVAEVVQPQGSAAVMLVAFVYTAPVQGHEEKTQLLLREPDENFLQACAAAVARLEGVLPAHMIPTAMCPLYRVPYGATSKIDRRQLRQAAERLTPEQLQAYTTGVADNCKNVSKEPPVSAAEKKWQALWARVLGVPTQRIGRDDLFFRLGGDSLSVIRLLDLAGQEGLPHLTFQDVLQNPRLREIAALSETRDSSRGSDDNDDGPAPFALVKDADALLRVATNLIAATVHQRGAYQAWAVTAKCNPILRTRIFQTPDGSSYQAVLNSPLNWSRHETLDDVFASQPVMGLGTPLAHLMLSPGHLHLVIHHALYDGWSLSLLVAEVDKAYLGLPLPPAAKFNNFIAHVESSMQIIDLPDNPTQSNVTVASKIKLAWALVSRAYTNNSDTVTGFVSSGRTAPVAGIVKVPGPTIASVPLRIRLSATQRYEHLGLQNISQQSEGGAAACQFQTLIAVEAKEHEVQGAGERHTWFCGEKTRPGGGAIEVTATFDPEVLASEQMHRVLAQLDHFLVQIQAVSEASATTIADLDILSDEDLQQLLRWNALPLPPTPWGCNRCVHDLVHDACQRRPAAVAIEAWDGQFTYQQIDDHVADLAHRIQTLGVVRPDTFVGLYIEKSRWTVVAQLAPLQRLRELCAITKLPLILTTEDQQEAVAGLFSLPTGCTRVKPSNAMYTIATSGTTGKPKVAVIEHGCFIANIQPIIDAVGINANSRVLQFAGYGFDAMLIEHMITLLVITEMGANWAMLTASVIQLLTPTNVPTLTTLVQAGEPMQQGIVDRWASHNCIPPGAAPYDIGYATGGVTWVVDPDTLDPVPIGAEGELIIEGDIVGRGYLNDLERTAAAFIPCPHWLADLRRSSNANGTEPGPGTQLHRVYRTGDLIKLRGQRLELTEVEHHVQQTFPGALQVVAAVSTLGAATDTDRTDILLPASNPDFHKAVETTELALVERVPAYMVPSIFIPLSRVPRDNNGKVDRRLINARLSSLSRKEADGYSPSSSAASTIVAPQNRLQHDIRAIWAGVLGMADEDIGIHNSFFRIGGDSITSMQHRTISQLALHATRKDDGEKRALPSEEEADVGLDHASVFLHLEGPGVGGAESMARALAVIVETHPMLRARFEKSSDGTWRQRVTGNADQSNYRYYHHGVTSQEQITSICSASQQALDIRHGPLLIIDQFERDDATTWLFLVAHHLVIDLVSWRVVLADLEQLLTTGERPKVPPTSFLRWCQLQADYAARLSAPHQVEEDQETDISAYWGKGVTRNTHRDVDRYALILDKQTSELLLTKANIALNTQPVEIVQAALLHSFVHLFPDRPAPIIFSEGHGREPWDATIDITRTVGWFTTICPAQVSLDASEDFVTALRRTKDARRRSPANGWEHFTARYLHPQGPKTMKGMEILFNYQGRYQQLERPDAMLKIDMANQFTAGDVAPDMQRFAPIEDRLYQWGPVCERSLRQAAAQLTGMSGHIQTVSDFPLGSSHVTSDLLDETLRTMRTRLANGRQLIVQDVYPCTPIQQGMLMGYTRTPWHYEQVLTWRVVGASLRDVARLQAAWQHVVNAHPALRTVFLQTSDGHIEQLVLQDYTPVVRIHQDSSHQSHAPEPEPVSLDALKPLHELHVHTSSTSGDVVLRLHINHALVDGTSTKILRRDLVCAYEGQPLPTMMLESQSYRDYVEYMLTQAASLKSHQYWQSHLQGALPCLVPSLQGHDGSNDLPQSVSTIRSFTMELGPTEALDTFCEVHELALTVLFHVAWALVVKQYTASEDVCFGYIASARHAPVQGIDDMVGPLINMLVGRIDMPAGMTLLSVLQQYNRTYLHSLEHQHQPLAEALNAIGSTSGELFNTLLTVQYQQDPRKDAAGDPSGIVLLDEDMEDKSEYPVTLNVAVFPDRVELLFSHHTAHMSDWYAARMARCFRHALAEVLTHPSLPVGEIQVVDDSQRQQILQRNEPLADPVNTCVHHIIHQRCLDFPASAAVCSWDGEFTYEELDTVSSALAEELIDYSIGVDMTIPVLLEKSRWVPVAVLGILKTGASFVLMDASHPEARLRGLCEDVQAPLILASRGTFSKASNLAPHVVCLGERLLGEIACPHPARWSRVPVCASNAAYTVFTSGSTGKPKGAILDHSCLATAAKHLQSCMYMNSASRVLQFSSHAWDIAVADIVLTLLAGGCVCIPSEEERTGDIAAAANRMRVNWAILTPTVSRLVKPGALKHLQTLVLAGEPLSPSDLAIWHDKVRLISAYGPAECCPISTVSEPLTASSNPRDIGRPPANVAWIVDRDNHARLVPEGVVGELLLEGPTVGRGYVNNAQQTAAAFIDPPLWLRGLRHGQSSTRLYKTGDLARFTPDGRLIFVGRKDNQIKIRGQRLELGEVEAQAGIAFLNRDVTVELVGQADDAFLVAFVHPMADDHESPAAGTGSLLRQPHSQQFQESVRAAISTLREALPSYMVPTAFLPLAWVPKSPTGKTDRKRLIELAASLSQSELDVYSGTNATRRTPSTPLEAQLQDLVARVLKRSPGSIALDEDLFHIGLDSLRAMTLASLAAKEGLKLLALTIFQHPRLSQLAAVLEEGARAAAVSSTTSSSPQSTPNPLLDSVDDLCTKWKIDRSQVADVLPTTFYQRGSLDCQHLAHMVLTFSQPVDVARLQSVVVAAIRHYDILRTVFVPFENTTVQLILHKMSLPTVEIQTDKDLQSTVQSICQQDIQTPIPPGHPVTRLFFVISRKQDDNHLAMILRLHHAQYDGVSIRRIHNYITAAYEEPTHPPLTTAGYADFLNARRHHQHASTFQFWRDLLHGSTMTCLASGGGHISTTTHRHRMDLLVTSAREIPRPRLQPGLTMATYLKAAWALVLAAQTHTHDLVFAQLVSGRNLPVPDIDRIVGPCINYIPVRVTLQPTWTCSELLRNVQAQHIRTMAHDAVDFDELVARSTAWPAGTEIGTGVHFLHGDRFWDEVRTVAGVECRSQHVDFKLLQTYPMLTCTGSPDAEEATGRSVLGVALTSAVFGQEVADRVFEVFLGMLDYLTTTPEKLVAEVI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016874",
                "GO-Name": "ligase activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 4114,
                "End": 4190
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2635,
                "End": 2674
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 772,
                "End": 846
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 779,
                "End": 849
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2636,
                "End": 2700
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 4120,
                "End": 4190
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2623,
                "End": 2685
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 772,
                "End": 844
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1745,
                "End": 1818
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4112,
                "End": 4186
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 773,
                "End": 849
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 4146,
                "End": 4161
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1745,
                "End": 1822
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1777,
                "End": 1792
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 781,
                "End": 845
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1756,
                "End": 1817
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 4122,
                "End": 4185
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2638,
                "End": 2672
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 805,
                "End": 820
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1745,
                "End": 1816
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4114,
                "End": 4187
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1846,
                "End": 1977
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3126,
                "End": 3309
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 4114,
                "End": 4190
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2183,
                "End": 2511
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1288,
                "End": 1622
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 227,
                "End": 628
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2635,
                "End": 2674
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3604,
                "End": 3995
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 772,
                "End": 846
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3578,
                "End": 3980
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2512,
                "End": 2613
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 779,
                "End": 849
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2636,
                "End": 2700
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 4120,
                "End": 4190
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2623,
                "End": 2685
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 772,
                "End": 844
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1745,
                "End": 1818
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4112,
                "End": 4186
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 773,
                "End": 849
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 4146,
                "End": 4161
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1290,
                "End": 1595
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3589,
                "End": 3924
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2290,
                "End": 2361
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 235,
                "End": 576
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1745,
                "End": 1822
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 1777,
                "End": 1792
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3981,
                "End": 4103
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 630,
                "End": 761
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2692,
                "End": 2846
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 879,
                "End": 1043
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 890,
                "End": 1212
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 3128,
                "End": 3565
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 4249,
                "End": 4648
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 2722,
                "End": 2998
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 377,
                "End": 388
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 781,
                "End": 845
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1756,
                "End": 1817
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 4122,
                "End": 4185
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2638,
                "End": 2672
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 805,
                "End": 820
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1417,
                "End": 1428
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4226,
                "End": 4395
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1623,
                "End": 1717
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1745,
                "End": 1816
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4114,
                "End": 4187
            }
        ],
        "ipr_mapped": [
            46,
            45,
            29,
            30
        ],
        "response#1": "MSDTAERVKKIVVEHLGVDADKVTPEKSFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDAVKFIDANTPPKSDTADKVTPEKSFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDAVKFIDANTPPKSDTTITIPPMSDTAERVKKIVVEHLGVDADKVTPEKSFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDAVKFIDANTPPKSDTTTTITIPPMSDTAERVKKIVVEHLGVDADKVTPEKSFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDAVKFIDANTKS",
        "response#2": "MSDTAERVKKIVVEHLGVDADKVTESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFIDSAAKSSSSSSTSSSASSSSSSSPSSTNHSLSLPSSPSPHPTPHPPSPSHHLLLHHHPSHSITTSSSRRHPHLNRTTTTRTFTTTTPRRTLRTARTRTNPRTTMSDTAERVKKIVVEHLGVDADKVTESASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFIDSAAKS",
        "response#3": "MSSDDIAARVKKIVVDHLGVEADKVVDSASFIDDLGADSLDTVLLVMAFEEEFGIEIPDDAAETILTVGDAVKFIESAQKSGSVTALTLDDALFHGGRVKRDKVVDSASFVDDLGARSLDTVLLVMAFGDDAAETILTVGDAVKFIESAQKSTSVTALTLDDALFHGGRVKRDKVVDSASFGGRLVFCEGRGVLVLGARLTGEDGCGGPTEAALSWTWSASTTHCCLTVTHNTTPTVLRTGEIRTPITEVNEKPKTRTTMSSDDIAARVKKIVVDHLGVEADKVVDSASFIDDLGADSLDTVELVMAFEEEFGIEIPDDAAETILTVGDAVKFIESAQK"
    },
    {
        "reference": "MIAVNSRNSLNADMTSLHPETLMVHGGMKGLTEAGVHVPAIDLSTTNPVNDVATGGDSYEWLATGHTLKDGDSAVYQRLWQPGVARFETALAGLEHAEEAVAFATGMAAMTAALLAAVSAGTPHIVAVRPLYGGSDHLLETGLLGTTVTWAKEADIASAIQDDTGLVIVETPANPSLDLVDLDSVVSAAGNVPVLVDNTFCTPVLQQPISHGAALVLHSATKYLGGHGDAMGGIIATNADWAMRLRQVRAITGALLHPMGAYLLHRGLRTLAVRMRAAQTTAGELAERLDAHPAISVVHYPGLKGQDPRGLLGRQMSGGGAMIAMELAGGFDAARSFVEHCNLVVHAVSLGGADTLIQHPASLTHRPVAATAKPGDGLIRLSVGLEHVDDLADDLIAALDASRAAA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within PyrdxlP-dep_Trfase_small, PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_major sharing conserved structural features; 2. The protein must be able to perform the lyase activity,lyase activity,pyridoxal phosphate binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004123",
                "GO-Name": "cystathionine gamma-lyase activity "
            },
            {
                "GO-ID": "GO:0018826",
                "GO-Name": " methionine gamma-lyase activity "
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": " pyridoxal phosphate binding "
            }
        ],
        "go_f_mapped": [
            32,
            32,
            33
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 270,
                "End": 401
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 61,
                "End": 400
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 269
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 402
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 270,
                "End": 401
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 61,
                "End": 400
            },
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 399
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 269
            },
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 403
            }
        ],
        "ipr_mapped": [
            73,
            74,
            75
        ],
        "response#1": "MTRPPPPPPPPAPPPPAPRPVRLNGNGNAAPVLRAAVEAALAAPLTDPGPGAPGNRYGSAAYRALEDRVRARLADLYALPEGYRVALTPGGTAALHAVLAALARPGDTVLLPADGYGGHPATPAAAGLRLVPVPLGPDLRPDPDAVRRAVAEHRPRAVLVSAVDPRTGRRLPLAAVAALCREHDALLVADAAHSTGRAAHPPDPSPARLGADLIAGSLHKTLAGPRGGVLAARADHPLLDRVDAAVEGGTTSRTDAAAVAAALAVLDLAAREEPARRARVAANTARLRARLADLGIPLTGPAENLLLTLRLPDAATVRAGHRALLDRGLDVTLLPRPGRPAAPPALRVSASPVHTLDDVDRAADALAAVVRDLPAPPRPAPGGPR",
        "response#2": "MTTPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAPPPPAPPVDLTCCENAHGPPPAVRRALARAVRADRPTPYGPSAAYAELERRVRAVVARRTGLPAPDEVALTPGGTDAVHLAARALARPGDTVLLPRAGYPGHPAAARAAGLRVVDVPPGDPEDVRARLAAVRAAGERPAAVLVQPGPPERPTPADLAAWRRAAPDALLVADASQLAFGRPGAPAADAVAAGADVVTLSLSKALAGPRGGVLAARADLRDRVRAARARAGGTRAADALAVAAALAVLDDPAYLARVRARAARLRDRLLARVPRDVAVPPAGAHVLVRCPDPARVRALHAAAAARGLRLRLYTGPDGPAVRASPAPHVTDEQLDRFADVFTAAADEAPPPAPPATPPPPPPPPP",
        "response#3": "VSRERPATVTVVADAAAVGDADRTVADAVADGADAVRTATVDVAAADAAADAAAREAVDAAAAAVDATVVDVGRTVAWAVDAAAAGDADVAVVVDDAVDADADAVAAATADADATVVVGGAAAGADAVAGAVADAGGAVVVDGADPADAVAAVAALVDGAVVADGGALAGDGDGGTVVAAPAPDPPPRPGARRRRRRPRRPPRGPRPPPLRRPRAPPPRRRRPPRRPPPRPRPRPRPRARRPRPGPRPRRPRPPRPPLRRPVPGPGRPRPPRRPPLPRRRPRPRPPGRRRRRPRRPPPRRPRRRARPRPRPRGHRARPRPPARPPPPTP"
    },
    {
        "reference": "MTQLPYLLDRRGGALAAPATAWGDMMLNRALFSVALLSSVGSAWVVLSYACIKELRSYRHQLILGLAISDLLMSLNFMFSAGWNVAGGDLALEESRTACSVNGFLTQVFVVQTDWWILVIAIATYIILGNFKTQSQFIQTHVWIPWVGPWVLSIIIAAICHGVLGYGYIGGWCWLTSDLMRLLINFIPRWLIVIAIALIYIRLYMIVRKARKWDIEGVSPDPGDDMADTSVILMSVGKKDRERQGSGVLVSRDVSVSFGRKGSTAPTFVTMVTTSGAGDSREAISSCSAREEGSRARTVNVNSSRSLSLGMRQPLNAAQLKRIAKKMMVYPVAYAIIWACPTAIRIYQGTTGSRAPLWITIVDKSCIVIQGLVDAVVYGLNERAWQGWRDHIRRIIYKNEGGRIIG",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein must be able to perform the G protein-coupled receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            }
        ],
        "go_f_mapped": [
            0
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 378
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR022596",
                "InterPro-Name": "GPR1_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 318,
                "End": 386
            },
            {
                "InterPro-ID": "IPR017981",
                "InterPro-Name": "GPCR_2-like_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 212
            },
            {
                "InterPro-ID": "IPR023041",
                "InterPro-Name": "Glucose_rcpt_Git3_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 40,
                "End": 210
            },
            {
                "InterPro-ID": "IPR022343",
                "InterPro-Name": "GCR1-cAMP_receptor",
                "InterPro-Type": "FAMILY",
                "Beg": 99,
                "End": 117
            },
            {
                "InterPro-ID": "IPR022343",
                "InterPro-Name": "GCR1-cAMP_receptor",
                "InterPro-Type": "FAMILY",
                "Beg": 57,
                "End": 72
            },
            {
                "InterPro-ID": "IPR022343",
                "InterPro-Name": "GCR1-cAMP_receptor",
                "InterPro-Type": "FAMILY",
                "Beg": 38,
                "End": 56
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 378
            }
        ],
        "ipr_mapped": [
            1
        ],
        "response#1": "MVGRQDSQTREIPLLLIFSEIMHVDAGEGNHTAVTEFILLGLTDRPELQVILFGLFLSMYLVTVLGNLLIILAIKVDSRLHTPMYFFLSNLSFVDICYSSVTVPKMLVNFLSEKKTISYPGCATQLFFFHFLGGTECFLLAVMAYDRYVAICNPLRYTVTMSKQVCVLLVAGSWVGGSVNALVHTLLTFRLTFCGPNVINHFFCDIPPLLKLACSDTHINELVVFISSGFIILITFLLILTSYVYIVSTILKIRSTEGRHKAFSTCASHLTAVTLFYGTIIFMYVRPKSNHTPDKDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRVLGRKIFSSGS",
        "response#2": "MWNKLTQMKEGNHTAVTEFILLGLTDRPELQILLFGLFLSMYLVTVLGNLLIILATRSDSRLHTPMYFFLSNLSFVDICYSSVTVPKMLVNFQAERKTISFNGCATQLYFFLALGGTECFLLAVMAYDRYVAICNPLRYSVIMSPQICSLLAAGSWVGGFVNAMIHTVLTFQLTFCGPNEINHFFCDVPPLLKLACSDTTINELMVLFISCLLILVATFVIILISYILIVSTILKIRSTEGRHKAFSTCASHLTVVTLFYGTITFMYLRPKSYHSPDKDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRLMGRKRVFRKKEYLQQRTP",
        "response#3": "MGEENHTLVTEFILLGLTDRPELQVLLFVVFLSIYLVTVLGNLLIILATRIDSRLHTPMYFFLSNLSFVDICYSSVTVPKMLVNFLSEKKTISYSGCATQLFFFHLFGGTECFLLAVMAYDRYVAICNPLLYTVKMNRQVCVLLVAGSWVGGTVNALIHTSMTFILSYCGSNEINHFFCDIPPLLKLACTDTSVNELVMIISSSLFVTVTPFIFILISYMFIISAILKISTEGRRKAFSTCSSHLTVVSLFYGTVI"
    },
    {
        "reference": "TTIILLIAFAAIQLSKADDLKFVFVMARGGDFVAGDYAGGPKIINKEAKDSELTEQGKQEAFQLGTKLSELYKTKLGVSKWDSKTTYWPVALSQKRTQVSTLITGAGLEGDQSKRNKAWTNEELKATSFPAMESFSRFIKPNECPKYLEELMKQKQEISTILKECSSSVQQVKSKYSAVNVNLPQHIWLAYETLKKLKRQQPSSSTWMTDDLMKNLRECSAKITWLATTKTDTLRKLSGGLLLNDLFNDMDQITQGKAQPNAPGGKDSKLNVFTVSQFLVISQLAAFMPEGSKLNNKAVTASDIYPEDGSHVDIEMYQENNKWSVKLVYVSGKDKQPQTITLPGCQEKCPYEQFKSALQKYKITDEEHQKACKN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within His_PPase_superfam, His_PPase_superfam sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016791",
                "GO-Name": "phosphatase activity "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 374
            },
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 372
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 374
            },
            {
                "InterPro-ID": "IPR029033",
                "InterPro-Name": "His_PPase_superfam",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 372
            },
            {
                "InterPro-ID": "IPR050645",
                "InterPro-Name": "Histidine_acid_phosphatase",
                "InterPro-Type": "FAMILY",
                "Beg": 15,
                "End": 372
            },
            {
                "InterPro-ID": "IPR000560",
                "InterPro-Name": "His_Pase_clade-2",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 329
            }
        ],
        "ipr_mapped": [
            509
        ],
        "response#1": "MADTTVLVLLRHGEAELPAGRRYDTGLSERGREQARAAGRAAAAAGLRPDVLYCSPLTRARETAEAAAAELGLEPRTDERLREMDFGDWEGLTFAEIAERDPEALRAWMADPGHARPPGGESFADLTARVTPFLREAAAAHRGRTVLVAAHGGSIRAAVTLLRGLPPEALFQLEIPTGVPLVFELDERGAVTAEHRLDPGAA",
        "response#2": "MNWKEIRTLKGHTDWVTSLAFSPDGKILASGSYDRTIRIWDLETGKEIRTLKGHTDWVTSLAFSPDGKILASGSYDRTIRIWDLETGKEEIRTLKGHTDWVTSLAFSPDGKILASGSDRTIRIWDLETGKEIRTLKGHYWVTSLAFSPDDKTIRIWDLETGKEIRTLKGHTDWVTSLAFSPDGKILASGSYDRTIRIWDLETGKEIRTLKGHTDWVTSLAFSPDGKILASGSYDRTIRIWDLETGKGKEIRTLKGHTDWVTSLAFSPDGKILASGSSYDRTIRIWDLETGKEGKEIRTLKGHTDWVTSLAFSPDGKILASGSYDRTIRIWDLETGKEIRTLQ",
        "response#3": "MTTPATPATPATPATPATPATPTPATPATPATPATPATPATPTPATPTPATPTPATPATPATPATPATPATPATPATPATPATPATPATPATTLRYGTRTDRGHVRTRNEDSAYAGPHLLAVADGMGGEPAGDLASAAAITALGHADLTPHRPADAQPTPTERLHHAVLAAHDAVHTLATDHPECAGMGTTLTALLLTHTHLALAHIGDSRAYLLRDGTLTRLTTDHTLHEQLTRTGTAPPNALTRWLGTDPDEPPEPDYAFLPARPGDRLLLCTDGLWNYLTDTEIADTLTTTGPDALADLLARLADTDPQHAADALVDLALARGGHDNTTVLLADLADTDTTPDTPAPQGAP"
    },
    {
        "reference": "MTVTKIEIPTIDLRGYYEPTSPTSKEEVVAQVRAACLEHGFFQIEGHGVSLEVQRNMLAACKTFFDLPTDQKAELSLYKNTWRRGYEGYGEQTPHHAVLPDQKEAFFVGRDLPEDQIGFLKGPNVWPEQVPTNQFRGPVEEYFEALLKLGHRVMEVLVVGMGHPPSILDSFTGNAAMFLKLLRYPEHTFTDPRVFGSGAHTDYGGLTILLQDPGKHGLEVYHAATEQWIPVPAVEDRFVINLGDMVQRWTDGEYKSNLHRVLNKASGERFAVPAFWHGDLEATNPLNPNDTSGETVQDFIRKKFYRDYSLPLAEEKGTAVAV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Oxoglu/Fe-dep_dioxygenase_dom that are essential for its biological function; 2. The protein must be able to perform the cation binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            183,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 172,
                "End": 279
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR027443",
                "InterPro-Name": "IPNS-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 310
            },
            {
                "InterPro-ID": "IPR026992",
                "InterPro-Name": "DIOX_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 8,
                "End": 129
            },
            {
                "InterPro-ID": "IPR044861",
                "InterPro-Name": "IPNS-like_FE2OG_OXY",
                "InterPro-Type": "DOMAIN",
                "Beg": 182,
                "End": 277
            },
            {
                "InterPro-ID": "IPR005123",
                "InterPro-Name": "Oxoglu/Fe-dep_dioxygenase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 172,
                "End": 279
            },
            {
                "InterPro-ID": "IPR050231",
                "InterPro-Name": "Iron_ascorbate_oxido_reductase",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 287
            }
        ],
        "ipr_mapped": [
            871
        ],
        "response#1": "MPDRDRPTVVVVAAPAGTPDRERAERVAAWLRADGADVRVVDAADATRDADSVDVVAAADGADRDADSVDVVADASDDADAVDTDSADVDSAVVDSADAESADASADAAPVDVDSVDLVVVCGPDVRTACAAAARDAGVPLVLVDRRGAVVAPDGAVVVDAEGAAGLRPAADDVDATHGTDGDADAPERTDAAERTDAAERTTDGHAAPEDTDGDAALEDADEDADEDASDRVSDRVSDRVSDETTNRETGTDTERATERERDTERDTERATDTDEPVAR",
        "response#2": "SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSRRPRPRPPPPPPPPPPPPPPPPPPPPPPPPPPAAAAAAAAAAAAPRRPARRRRPAAPPPAPRTRRRTRRRRPAAAAAAAAPRRRRRRRRRPARRPAATRAAAAAAAGAAAGAGGGGGGGGGGGGGGGGGRRRRRRRRRGGGGGGGRGGGGGGAGGGGEGGRGGGGGEGGGGGGGGGAGGGGGGGGGGGGPPPPPRPRRARRPPPPPPRPRPPPPPRPRPPPPPRRPPPRRRPPPPRPRRPPAARRRAAAAAAAAAAAAAAAAAARAAAAAARPPPRRRRRRRAAAAAAAAGRGGGGGGG",
        "response#3": "MATRTPTRTAPTSRTTTPSRTAPPSRTATSRTATAATAATPSTATAPARPPATTPATPRRARPAPGPTAPGPTSRTATPTRPTRPAATATRATRTTRTARTAPARTAARTPTPTAATRTATARTTATRTPAPTATPAPRTPARTPTPTATPPTRTAPRTARTATPTPTPARTARTAPTARTATAPTAPTRTATAPTARAARAPAPARTAPAGRAARPARTRPAPPGRRRPAAARARPRCRRAPRRRRRRRCSRPSPSRSARRRRRRRRRCRRC"
    },
    {
        "reference": "MAVVPGGPSSRPAVGAQFFCTAGRGLEPFLMREVRERLAATQVEYISGKVFFTTCSDLNMLKQLKSAERLFLLIKKQLPFPVSSVSKGKILNELQRLINDDPESWLNAISIWKNLLELDAKKEKLSHKNANPLKRKVGEDDITAKKLKTEQIQELQETKECQLEKQIEEKILEQGNFITEGEKFQKLQDDVTEAVDTRNQTNLTFRVSCRCSGAVAKTLTAQEVGRVIGIALMKQFGWKADLRNPNLEIFIHLSDVYSVLGIPVFRVPLACRAYIKTAGLRSTIAWAMASLAEIKAGAVVLDPMCGLGTILLEAAKEWPHVYYVGADVSDSQLSGAYDNLRAAGLRDKIELLQVSVIELPLPSESVDIIISDIPFGKKFKLGKDIKRMLQEMERVLRVGGTIVLLLSEDHHRHLKGGEASSGPLNSQGGHTEEPGGEERLTPAEKAAVSEPVSSPFAASNQGRLDRMPPLGSLVPVDCYRVSLGKTDALISKYKKSHSPGR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more THUMP_dom, RlmKL-like_Mtase, THUMP_dom, THUMP_dom that are essential for its biological function; 2. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 3. The protein must be able to perform the RNA binding,methyltransferase activity,S-adenosylmethionine-dependent methyltransferase activity,methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding "
            },
            {
                "GO-ID": "GO:0106346",
                "GO-Name": " snRNA methyltransferase activity "
            },
            {
                "GO-ID": "GO:0016423",
                "GO-Name": " tRNA (guanine) methyltransferase activity "
            },
            {
                "GO-ID": "GO:0160230",
                "GO-Name": " U6 snRNA (guanine-N(2))-methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            96,
            20,
            302,
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR004114",
                "InterPro-Name": "THUMP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 149,
                "End": 264
            },
            {
                "InterPro-ID": "IPR000241",
                "InterPro-Name": "RlmKL-like_Mtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 272,
                "End": 410
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 270,
                "End": 421
            },
            {
                "InterPro-ID": "IPR004114",
                "InterPro-Name": "THUMP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 176,
                "End": 264
            },
            {
                "InterPro-ID": "IPR004114",
                "InterPro-Name": "THUMP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 186,
                "End": 254
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 284,
                "End": 406
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR004114",
                "InterPro-Name": "THUMP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 149,
                "End": 264
            },
            {
                "InterPro-ID": "IPR000241",
                "InterPro-Name": "RlmKL-like_Mtase",
                "InterPro-Type": "DOMAIN",
                "Beg": 272,
                "End": 410
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 270,
                "End": 421
            },
            {
                "InterPro-ID": "IPR004114",
                "InterPro-Name": "THUMP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 176,
                "End": 264
            },
            {
                "InterPro-ID": "IPR004114",
                "InterPro-Name": "THUMP_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 186,
                "End": 254
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 284,
                "End": 406
            }
        ],
        "ipr_mapped": [
            976,
            972,
            70
        ],
        "response#1": "MGPRAGPRARARARAGARAGARARAKAEARARPGARPRAGARARPRTGPGPPRARARPGAGPRAGPGARPRAAPRARPRTAPRAGARPGARAAAPGPAPGTGPGATPGAGAARAGPRPAPAPPGARPGARPRAPGARPGARGRSRPGARPGTGPRAGPGPGPAPRTPRTGPAPGPGPGPGPGPGPGPAPAGAPTGARPGAGAGPRAGPGPGPGPGPRAGAGAGPRAAPRPGPGAGAGARPGPGAGRRTGPGARPGTGPRTGARTGAGAGAAPRTGPRTGPRTGTRTGPRAARRRTAPRTVPGPGPRAGRRAATGPGTGRRTGRRPAPRAGTGRPRTPPRTGPGRP",
        "response#2": "MPRPRPPPRRPPPTRRRPPRPRRPRRPRPPPRPRRRRRPRPPPPRARPARPAPPPPAPRRPPRPARPRVLDLGAGWGALTWHLAREPAERVLAVDRDPAALERARANAAAARGEAGGRAPAVELREGDAARLSWPSPPGERFDLVVCDPPPGGDPETLAALARELAAALAPGGRLLVAGGRDRDARALAAALEEAGFTARVRERAAPGRGRRWLVEAERRPAARPAPAPPPPPATARRP",
        "response#3": "RTRTHTRTHTHTPTHATHTHAPTHAHTHTPTRTRTRTRTHARTHARTHTHTRAPTRAHARAPTHARTPTHARAHAHARTPTHAPTHPRTRTHAPTPAAHAHTLTPTHAQTRARTPARTPTHAPRHPRTHAHARTRARTAHAPTTTHTHAPARTHTHARTPTHTPTPRAHTRTHARAHAHTPTPRAHAHAPTPTHAPAPTPTPHTRTRARARARTHTRAHARAHAHARTHAHAHARTPTRAHAHARTHTHALARTPTPHARACTHTHAHTHTHAHAHTRTHARAPAHTHAHTRARARTRAPTPTARTPTCARAHAHTRAHTPTRARTPRRTRTRARTPTHAHTPART"
    },
    {
        "reference": "MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNESGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIVCDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSVSPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding,nucleotide binding,pyrophosphatase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016462",
                "GO-Name": "pyrophosphatase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            },
            {
                "GO-ID": "GO:0005525",
                "GO-Name": " GTP binding "
            },
            {
                "GO-ID": "GO:0003924",
                "GO-Name": " GTPase activity "
            }
        ],
        "go_f_mapped": [
            31,
            61,
            341
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 210,
                "End": 222
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 317,
                "End": 352
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 181,
                "End": 381
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 428,
                "End": 597
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 14,
                "End": 215
            },
            {
                "InterPro-ID": "IPR021181",
                "InterPro-Name": "Miro",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 631
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 210,
                "End": 222
            },
            {
                "InterPro-ID": "IPR020860",
                "InterPro-Name": "MIRO_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 429,
                "End": 592
            },
            {
                "InterPro-ID": "IPR001806",
                "InterPro-Name": "Small_GTPase",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 182
            },
            {
                "InterPro-ID": "IPR013566",
                "InterPro-Name": "EF_hand_assoc_1",
                "InterPro-Type": "DOMAIN",
                "Beg": 354,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 317,
                "End": 352
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 181,
                "End": 381
            },
            {
                "InterPro-ID": "IPR001806",
                "InterPro-Name": "Small_GTPase",
                "InterPro-Type": "FAMILY",
                "Beg": 436,
                "End": 561
            },
            {
                "InterPro-ID": "IPR001806",
                "InterPro-Name": "Small_GTPase",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 179
            },
            {
                "InterPro-ID": "IPR005225",
                "InterPro-Name": "Small_GTP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 16,
                "End": 175
            },
            {
                "InterPro-ID": "IPR052266",
                "InterPro-Name": "Miro-EF-hand_domain",
                "InterPro-Type": "FAMILY",
                "Beg": 149,
                "End": 455
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 191
            },
            {
                "InterPro-ID": "IPR027417",
                "InterPro-Name": "P-loop_NTPase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 490,
                "End": 591
            },
            {
                "InterPro-ID": "IPR020860",
                "InterPro-Name": "MIRO_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 181
            },
            {
                "InterPro-ID": "IPR013567",
                "InterPro-Name": "EF_hand_assoc_2",
                "InterPro-Type": "DOMAIN",
                "Beg": 232,
                "End": 317
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MNTKDKINLKNIYDEEEINKEIKELKEKISEEIENEINKNIENIENEIIKVENTIKNNFENIINKEKLEINENIKIEIEEINKNIENINKNIKNNIKNEIYIIKKENKEIEKEINKLKENLKNEIENEIKIEIENIKNKIENNIIKDIENEIEKEMEKNINNINEKIENKINKIENEINENLQNLIKKEKNIIDKKINDINNEINEIKENIKKEIKNEIINKINNIKIEYIKNEINLKEKLNKIKNFEEKIKILINEIKEILNNIKEKNINIEKKIENIINEEKNEKVKINKNENEIEETIKNIIKKLF",
        "response#2": "MNFIKFNFIIKYKFKYKNFYFKKYIILKYFKYNFHNFKKNNNYINNLNFEKNNFINNKFFIFNKKLFNKNIIFIKNKILIINKNNFGKIFKINKIKNFFNNYFLNKKIFIKNSKFINKKINYNINFKNFIFFYNKFFNIYNFIFLKIIKKNFFIKNFFIIKYKNFLNFYIFNKFYYFKLLVMNKNKIFFNKIKNNKLNFKINIFKFNFKIFFNFKIFKKKKKIINFYYIFYKNNKKIFINYNFNFIFKKNIKIFKNFNNIQNLFNIKNINFKKNNFFINNNYKNKKNYFININFFKKFLNIKKNFIKINNFFNNIFFNNS",
        "response#3": "MDLKKFNLKELNFENFDFENFEKFEKNFENFENFEFKKNFDFENFDFKNFIKDFEKSENLNIDFENFEIKNFKIENFENFDLKDFENFENFDFEKLNFENFKKNEIKNFDFENLKDFENLKNFENLNFENFENFEIKNFDFENFEKKNVDFENFKNLIKDFENFEIENLKKNEIKDFENLKKNEIKDFENFIKNFENFEFKNLKFENLNFEDFEKNGVKDFENFEKDFKNFNLKFNDFENLNLKFENFEKNFNFEKFNLNFENLNFENLNLNFENFEKNFKDLNFENFKFENLNF"
    },
    {
        "reference": "MELFFICGLVLFSTLSLISLFLLHNHSSARGYRLPPGRMGWPFIGESYEFLANGWKGYPEKFIFSRLAKYKPNQVFKTSILGEKVAVMCGATCNKFLFSNEGKLVNAWWPNSVNKIFPSSTQTSSKEEAKKMRKLLPTFFKPEALQRYIPIMDEIAIRHMEDEWEGKSKIEVFPLAKRYTFWLACRLFLSIDDPVHVAKFADPFNDIASGIISIPIDLPGTPFNRGIKASNVVRQELKTIIKQRKLDLSDNKASPTQDILSHMLLTPDEDGRYMNELDIADKILGLLIGGHDTASAACTFVVKFLAELPHIYDGVYKEQMEIAKSKKEGERLNWEDIQKMKYSWNVACEVMRLAPPLQGAFREALSDFMYAGFQIPKGWKLYWSANSTHRNPECFPEPEKFDPARFDGSGPAPYTYVPFGGGPRMCPGKEYARLEILVFMHNIVKRFKWEKLIPDETIVVNPMPTPAKGLPVRLRPHSKPVTVSA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen,heme binding,iron ion binding,monooxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            },
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0102373",
                "GO-Name": "beta-amyrin 28-monooxygenase activity "
            },
            {
                "GO-ID": "GO:0020037",
                "GO-Name": " heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            }
        ],
        "go_f_mapped": [
            15,
            12,
            13,
            14
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 345,
                "End": 356
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 289,
                "End": 306
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 417,
                "End": 426
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 437
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 416,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 278,
                "End": 295
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 449
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 384,
                "End": 408
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 451
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 476
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 419,
                "End": 428
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 477
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 345,
                "End": 356
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 289,
                "End": 306
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 417,
                "End": 426
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 437
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 416,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 278,
                "End": 295
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 426,
                "End": 449
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 384,
                "End": 408
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 451
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 30,
                "End": 476
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 419,
                "End": 428
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 477
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "HLHDFVSSKIQEHVSATNDNNTETNSESESKDFLDVLLNLQKNNPELTLDNIKAIILDMFVAGSDTSSSTLEWAMTELLRNPRVMKKAQEELDRVVGKERRVEESDIIQLPYLQAVVKETLRLHPPAPLLLAREAREDVKLPSGYDVKKGTKVLVNVWAIGRDPTVWDDPLSFKPERFLDSSIDFKGKHFELIPFGAGRRICPGMPLALSTVELALAQLLYHFDWRLPGESPGEIDMSEKLGLTVHKAVPLMAIPVKR",
        "response#2": "MDQLSLLSLFLPLLLLIIFFFISLKKKKSSCSNIKNLPPGPWKLPILGNLHQLAGALPHHSLRALAEKYGPIMHLHLGEVSTVVVSSPEMAKEVLKTHDLVFANRPVLEATRILSYNSVDIAFSPYGDYWRQMRKICTLELLSSKRIQSFRGVREEKVGELVAGVRRSAERGEAVDLGKAAFTTALNILSNSIFSVDLAAYDGSEEFREEVREMTALVGTPNVSDYFPVLKGLDPQGIRRRMAANFGRFLKIIEE",
        "response#3": "MSTFAANVVKARYVLDAFPEWLRPLVAPFLSKTRKDIAEARKIIEPVIEERRRLKAEAAAAGNEATPKKYNDTIEWFDENAKGRPYDPAVAQLSLSVAAIHTTSDLLTQVLFDLCAQPELIQPLREEIISVIQEHGWKKTALYKLKLMDSVLKESQRLKPIGIITMQRVAMEDVTLSDGTFIPKGTKVAVAANAMWDAEIYPDPLKFDGYRFVKMREASEESGKKSDSGAQLVSTSPNHLGFGHGKHACPGRFFAANEAKIALCHILLKYDWKLEEGKQPKNIWNGIYLTADPSAKLMVKRR"
    },
    {
        "reference": "MATPQFSCLLPAFFLLVVFLFLLIKELRRYKSPKTTQKLPPGPPMLPIIGNLHQMASSLPHQNLKKLADKYGPLMHLKLGEISAVAVSSPRLAKEVLQTRGLAFADRPQSVVAKLMLHNCLGVTFSRYGDYWRQLRQIFAMELLSSKSVQSFSTIMEDELFAMVKSIESEAGRPIILADKLISYLYATLSRATLGRVCKGKETLIEVTGETLALSGAQSLEDIFPSVKIFAYLNPLRPKVRKLFNRIDGVLEDIINQQEKKLLSARVDNDQLQPEENDMLSVLLKLRNGKDSKVQVTNNDIKAIIFELFLAGTVGSSTTVEWAMSEMMKNPKVMEKAQHEVREVLKGKKRICQSDIQKLSYLKLVVKETLRLHPPAPLLFPRECRGQCEVDGYTIPAKAMVMVNCWALGRDPEHWIEADKFEPERFKNSSIDFIGNHFEYIPFGAGRRICPGISFGATNVELLLAALLYHFDWELAGGMHPKDLDMLELFGPGCTRKNPLSVIPSICIPSHDDN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 40,
                "End": 487
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 441,
                "End": 450
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 328
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 375
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 443,
                "End": 452
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 500
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 38,
                "End": 503
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 68,
                "End": 87
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 440,
                "End": 450
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 113
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 404,
                "End": 428
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 300,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 381
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 450,
                "End": 473
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 40,
                "End": 487
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 441,
                "End": 450
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 328
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 375
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 443,
                "End": 452
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 32,
                "End": 500
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 38,
                "End": 503
            },
            {
                "InterPro-ID": "IPR052306",
                "InterPro-Name": "CYP450_71D",
                "InterPro-Type": "FAMILY",
                "Beg": 63,
                "End": 507
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 68,
                "End": 87
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 440,
                "End": 450
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 113
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 404,
                "End": 428
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 300,
                "End": 317
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 381
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 450,
                "End": 473
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MPRLRRARKQIRNIITATIERRLAHPEEKPNDMLQWLMDNAETPEERDSVRLVHRQLALSFAAIHTSSMSMTHALYDLCARPEYVQPLREEIVQVIKEHGGWKKTALYNMKLMDSFMKESQRLNPPVVVSMFRVAMEDVTLSDGTFIPKGTKIAVAAYPIHRDEKYYPDAEKFDGFRFAKMREVPGQENSAQLVSTSPDHLGFGHGRHACPGRFFAANEIKIALCHILLKYDMKLAPGRPKNVTSGFFIASDPTAKILVR",
        "response#2": "MKAIILDMFVAGTDTSSSTMEWAMTELMRNPRVMAKAQEEVRTVVGSKGLVEESDIVNLPYLQAVVKETLRLHPPAPLLIPRECREDCKVSGYDIPKGTKVLVNAWAIGRDPLYWKDPLEFKPERFLESSIDVKGQNFELIPFGAGRRICPGMPLALATVHLALAQLLYHFDWKLPEGVKAEDVDMDEKFGLTVMKKTPLMVIPIKV",
        "response#3": "MILDLFAAGTDTSASTMEWAMTELIKNPRVMKKVQEEIDSVIGDNRERIIEESDIGKLVYLQAVVKETLRLHPPAPLLIPREATEDVVVSGYVIPKGTKVFVNAWAIGRDPTYWEDPLSFKPERFLDSSIDFKGKHFELIPFGAGRRICPGMPLALATIELALAQLLYHFDWKLPEGMKAEDVDMDEKFGLTLHMKHPLMVIPVKRT"
    },
    {
        "reference": "MAGESTQVDLSVKAIGWGAKDASGILHPIKFSRRTPGERDVKIRVLYCGVCNFDMEMVRNKWGFTRYPYVFGHETAGEVVEVGSKVQKFKVGDKVAVGCMVGSCGKCYNCENGMENYCPEPNMADGSVYREQGERSYGGCSNVMVVDEKFVLRWPENLPQDTGVPLLCAGVVVYSPMKYMGLDKPGKHIGVFGLGGLGSVAVKFIKAFGGKATVISTSRRKEKEAIEEHGADAFVVNSDTEQLQALAGTMDGVVDTTPGGRTPMSLMLNLLKFDGSLILVGAPETLFELPVQPLILGRRKIIGSSTGGLKEYQEMLDFAAKHNILCDTEVIGIDYLSTAMERIKNLDVKYRFAIDIGNTLKYEE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008106",
                "GO-Name": "alcohol dehydrogenase (NADP+) activity "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 161,
                "End": 324
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 16,
                "End": 355
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 161,
                "End": 324
            },
            {
                "InterPro-ID": "IPR002328",
                "InterPro-Name": "ADH_Zn_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 72,
                "End": 86
            },
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 359
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 187
            },
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 196,
                "End": 320
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 343
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 38,
                "End": 156
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MRILVTGGAGFIGSHTCELLLARGHEVVALDNLSTGREENVRPLLDHPRFRFVRGDVRDPEAVRAALEGVDAVLHLAAEVHVLAPPPPGTAPGLPPGAPRPQPPPPRPAEEEPERYVDVNVKGTLHLLEAARAARRPPRRFVLASSSSVYGEGEPPKDEETPRRPLSPYGASKVAAERLALAYHRTYGLPVTVLRYFTVYGPRQRPDMALWRFLAQALRGEPLTVYGDGGQTRDFTYVADVARGTVLALERGRPGEVYNLGTGQEVSVLELARLVARLTGAEVRHRPGDVRRTRADVSKARRELGYAPQVPLEEGLRRTVEWARRQPAAGSPR",
        "response#2": "MTTVLVTGASRGIGRATAEALPGHRTVRLDVTDPASVAAAVAEAGEVDVLVNNAGILHSGPAHEVTDEQWQRAIDVSLTGPFRLARAVLPGMLARGRGAIVNIASVAGFEGLPWSAAYSAAKAGLVGLTRSLAVEYGPRGVRVNAVVPGFVDTEMTADLPDVPLGRAGRPEEIAAAVAFLASDAASYVTGIVLTVDGGLTARRHVRTAAAPAAEDTTR",
        "response#3": "MGRLDGKVAIITGAASGIGEASAILFAREGAKVVVADIQEDKGNAVVEKIKKEGGEAIFVKTDVSKEEDVKKMVEKTVETFGRLDIAFNNAGIAGHEVPPPPPVRIEDITEEVWDRVIGVNLKGVFLCMKYEIKQMLKQGKGSIVNASSVAGLVGFPMQSAYAASKHGVIGLTKTAALEYADKGIRVNAICPGWINTPMIEKALAMAPNPEEVRKRLESMHPLKRMGKPEEVAYAALFLASDESSYVTGQALVVDGGMTASAF"
    },
    {
        "reference": "MGNEEAFTFALAMATGSFANMVLRAVVELDVFEIMKRAGPGTHLSAAEIAAHLPTKNPDANAMLDRMLRVLAGYEVLSCSNRSLPNGQVERLYGLSPVSQFFTKSEDGASLAPLCLLNQDKVYWESWYHLKDAVLDGGIAFNRAHNLTLYEYAGIDDRFNKVFNDGMSGCSTTIMKKMVENYKGFEGVSTLVDVAGGIGKNLNMIISKYPTIKGINFDLPHVIKDAPRCRGVENIGGDMFISVPQGDAIFIKWICCDWNDEHCLKFLKNCYAALPDHGKVILYEFIFPKASETSYAARVILNIDAVTLATVVGGRIRTEAEFEALAKGAGFEGFKMAYSTSEVDAVMEFLKKK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 351
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 108,
                "End": 339
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 351
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 105
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 102
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 127,
                "End": 332
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 351
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 332
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 351
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 108,
                "End": 339
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 4,
                "End": 105
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MTTPAEGDTSTAYSGTMRTDGDSWDLASSVGATATMVAAARAVATRDPAKPLINDPFAEPLVRAVGVDFFTRLADGELTADELDTDAGPQRMIDGMAIRTRFFDDFFLDATDAGIRQAVILASGLDSRAYRLPWPAGTTVYEIDQPQVIDFKTATLAELGAAPATADRRTVPIDLRDDWPAALRGAGFDPARRTAWSAEGLLIYLPPEAQDRLFDNITALSAPGSRLATEAMPGINFDEEKAAKMRERMRAMAERWRAHGFDLDATDLVYFGERNDVVGYLAGHGWRATATSVNDLLAANGLPPVADDDDEPFGDVTYVSAELVASSPHHN",
        "response#2": "MRDDDTWDLASSVGATATMVAAARAVATRDPKGLINDPFAEPLVRAVGVDFFTRLASGELDLDEIGDDAPGMQRIADGMAIRTRFFDDFFLDATGAGIRQAVILASGLDSRAYRLPWPAGTVVYEIDQPQVIEFKTTTLAGLGATPTADRRAVAVDLRDDWPAALRGAGFDTARPTAWIAEGLLIYLPPEAQDRLFDQITALSAPGSRLATEYMPDINADKEQFAERMRKMAARWRRHGLDLDVAALVYHGERNDVAAYLTAHGWRATATTVRELFAANGLPPIADDDNAAFGEVRYVSAELTTEATR",
        "response#3": "MAASTPSPTAPPPHTPAPPPAPPPQRRSSSRRLASRRPPSSSASALGSFHSSPGSAPAPPIFIDDDRDSYAGSSIASSTTSLASSILQYRFENGRTYHAYKEGKYFLPNDETEQDRLDLLHHIFTLTLDGKLYLAPLENPQRILDVGTGTGIWAIDMADKFPSAQVIGTDLSPIQPPAALVPPNCRFEVDDVEEDWTWPDNHFDFIHVRMLTGSIADWPRLYRQALRHLKPGAYFEQVEISWAPRCDDDTLPENCALAKWGNLFIEAGQKLGRTFTLVDTDLTKNLLVEAGFVDVVETVFKWPLNPWPTDPRLKELGRYYREVGLYCYEAFSEALSALSMAPLTRALGWTPTEIEVFLVDVRKEIKNRSIHAYWNIHVIYARKPE"
    },
    {
        "reference": "MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 2. The protein must be able to perform the nucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding "
            }
        ],
        "go_f_mapped": [
            61
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 386
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 386
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR004792",
                "InterPro-Name": "BaiN-like",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 387
            },
            {
                "InterPro-ID": "IPR023166",
                "InterPro-Name": "BaiN-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 261,
                "End": 317
            },
            {
                "InterPro-ID": "IPR004792",
                "InterPro-Name": "BaiN-like",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 387
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 386
            },
            {
                "InterPro-ID": "IPR055178",
                "InterPro-Name": "BaiN-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 192,
                "End": 334
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 386
            }
        ],
        "ipr_mapped": [
            43
        ],
        "response#1": "MPSFDVVNEANLVEVKNAIEQSNKEISTRFDFKGSDARVEIKEREITLYGDDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKPEKIGGDKVKQVTTVKKGISGDLAKKIIGTLKESKVWVRVKNIQDLKKIMPSFDVVNEANLVEVKNAIEQSNKEISTRFDFKGSDARVEIKEREITLYGDDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKPEKIGGDKVKQVTTVKKGISGDLAKKIVRTVKDSKIKVQASIQGDAVRVTGTKRDDLQSTIAMLRKDVSEVPLDFNNFRD",
        "response#2": "MAKAERNAARAAGDGDRSIKGGSSKVPKAHLSEVLAIPSCAETVKGAAKTKIEEAKEPSFDIVSEANMVEVKNAVEQSNKEISTRFDFKGSDARVEQKERELTLYADDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKIEKIGGDKVKQVVTVKNGIDGDLAKKIVRIVKDSKIKVQASIQGDAVRVTGTKRDDLQSTIAMLRKDVTDTPLDFNNFR",
        "response#3": "MPSFDVVSEANMVEVKNAVEQSNKEISTRFDFKGSDARVELKEREITLYADDEFKLGQVKDVLRGKMAKRNVDVRSLDYDKAVVQVKKVNKGVVEEAVKGVVREIKDSKTKVEASIQGDELRLYGDDDFKLQGVIDLLRGKLAKRNVDVRFLDYGKVEKIGGDKVKQVVTVKKGIDGDLAKKIVRIVKDSKIKVQASIQGDAVRVTGTKRDDLQSTIAMLRKEVTDTPLDFNNYR"
    },
    {
        "reference": "MDSPTLLLFIFASIFYFITFQIVKLGFNVVMTSKKTKRRRLPLPPGPKPLPIIGNVLELGPKPHRSFANLAKVHGPLMSLRLGSVTTIIVSSSDVAKEMFLKNDQPLSSNRTIPNSVTAGDHHLLTMSWLPVSPKWRSFRKITTFHLLSPQRLDSCCSLRQAKVQQLFEYVLECSRTGQTVDIGKAAFTTSLNLLSKLFFSLELAHHRSSKSQEFKDLIWDIMEDIGKPNYADYFPCLKYFDPCGIRRRLANSFEKLIEVFQGIIRQRLSLSSGSDTHNDVLDVLLQLYKQKELSMDEINHLLVDIFDAGTDTTSSTFEWAMAELIKSPKTMEKAQAEIKLVLGKESHIQESDIPKLPYLRAIIKETLRLHPPTVFLLPRKAETDVELYGYTVPKNAQILVNLWALGRDPKVWENPDVFLPERFLTCDIDVKGRDFGLLPFGAGRRICPGMNLAYRMLTLMLATLLQSFDWKLPNELNPRNLDMDEKFGIALQKTKPLEIIPVCKD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 501
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 501
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 441,
                "End": 450
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 438,
                "End": 448
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 318,
                "End": 344
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 448,
                "End": 471
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 71,
                "End": 90
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 95,
                "End": 116
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 298,
                "End": 315
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 402,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 361,
                "End": 379
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 362,
                "End": 373
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 439,
                "End": 448
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 448,
                "End": 459
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 309,
                "End": 326
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 44,
                "End": 494
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 44,
                "End": 501
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 28,
                "End": 501
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 441,
                "End": 450
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 438,
                "End": 448
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 318,
                "End": 344
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 448,
                "End": 471
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 71,
                "End": 90
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 95,
                "End": 116
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 298,
                "End": 315
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 402,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 361,
                "End": 379
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 362,
                "End": 373
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 439,
                "End": 448
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 448,
                "End": 459
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 309,
                "End": 326
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 44,
                "End": 494
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MIARVAFSKDLAALDVNSEQSKEFRDAVWAMMEEAGKPNVSDYLPILKPLDFQGIKRMKEATGRIHGILDGYIDERLAEKKASGEGYEPKDFLDVLLEEQEKGNLSRDNIKALLFDMFLAGTDTTSSTMEWAMSELIRNPRVMEKAQAEVDAAVGDEKRVVEESDISKLPYLQAVVKETLRLHPPAPLLLPRESKEDVKVMGYDIPKGTKVLVNAWAIGRDPTIWDDPLSFKPERFLEDVKDVDFKLIPFGAGRRVCPGMQLGLATVNLALANLLYHFDWKLPEESKESVNMEEKFGLTLHKKTPLMVIPIAR",
        "response#2": "MIDAENPRDFVDVLLELKEDGVLTMDNIKAIVFDLFVAGTDTSSSTMEWAMTELLRNPRVMQKAQEEIDSAVGKERRVEESDIVNLVYLQAVVKETLRLHPPAPLLLPRETIKDEKLPSGYVVKKGTKVLVNAWAIGRDPKCWEDAESFKPERFMESVVDVRGQHFELIPFGAGRRICPGMPLALRTVELALAQLLYYFDWKLPDGQHPDMSENFGLTLAMKTPLMAIPVPRV",
        "response#3": "PYNDTIQWFEENAKGSTYDPAIAQLSLSVAAIHTTSDLLTQVLFDLCANPELIQPLREEIISVVKEEGWKKTALYKLKLMDSVLKESQRLKPVNVIGMGRTATEDVTLSDGTYIPKGTRVSVAAYAMHRDKAIWGEDADKFDGYRFVKSPNSAQLVSTSPEHLGFGHGRHACPGRFFAANEAKIALCHILLKYDFKLVDGRPEVVNSGFFLSADPAAKVMVKRR"
    },
    {
        "reference": "MGSTSAERTQMGEDEACSYAMTITSGSVPPMVLKAVIELDVLEIIKRAGPGAHLSPAEIAAQLPATNPDAATMLDRMLRLLASYSILSYSLRTLPDGRVERLYGLAPVCQFLTKNEDGVTLGALSLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKIFNNGMSNHSTITMKRILENYKGFEGLSTLVDVGGGTGATLNMIISKHPAIKGINFDLPHVIEDAPTYNGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLNFLKNCYAALPDHGKVIVCEYILPVAPETSHAARTVFHVDAIMLAHNPGGKERTEQEFEALAKGAGFEGFRVACSAYGTKVMEFLKKA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 113,
                "End": 360
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 118,
                "End": 357
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 112
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 342
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 13,
                "End": 114
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 13,
                "End": 116
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 113,
                "End": 360
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 360
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 137,
                "End": 342
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 360
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 118,
                "End": 357
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MVHLAATRLPRNSPTAHICRRRPVTTTTYGATARTDGDTWDLASSVGATATMVAAARAVASRDPNALINDPFAEPLVRAVGVDFFTRLASGELDLDEVDADAAGMQRIADGMAIRTKFFDDFFLDATAAGIRQAVILASGLDSRAYRLPWPAGTVVYEIDQPQVIDFKTTTLSGLGAPTADRRAVPIDLRDDWPAALRAAGFDATAPTAWIAEGLLIYLPPEAQDRLLDNITALSAPGSRLATEAMPGITDFDEEKAEQMRARMRDMAARWREHGFDLDATELVYFGERNEVGDWLAAHGWRVTATRVNDLLAGYGRPVPDDDDMAAAFGDVSYVSAELR",
        "response#2": "MARTRNDDPAALLARGAEALGLTLSAEQQARLLRYLDLLVKWNKAYNLTAIRDPTEMVTRHLLDSLSVLPHLPAQARLLDVGSGAGLPGIPLAIARPDLHLTLLDSLQKKVRFLQQVSRELELTNVDVHAVRAEDWAASQRGQYDVVTARALAALPKLLGYCAPLLADGGRFLALKGQYPADEIAAAEGLTLLEVVPLTVPGLDAERHLVIIGKPAA",
        "response#3": "MASARTDGDSWDLASSVGATATMVAAARAVATRDPKALINDPFAEPLVRAVGVDFFTRLASGELDLDELDDEGAARMQRIADGMAIRTKFFDDFFLDATGAGIRQAVILASGLDSRAYRLPWPAGTTVYEIDQPQVIEFKTATLSGLGASPTADRRAVAIDLRDDWPTALRAAGFDPARPTAWIAEGLLIYLPPEAQDRLLDNITALSAPGSRFATEAMPDITVFDEERARAMRERWRRHGLDLDMSELVYHGERNDVAAYLAERGWRSATSTVRELFAANGLPVPDDADDAVFGELVYVSAELAPPPAPPPAGQPAGRLARGGSAR"
    },
    {
        "reference": "MAEIPTSSNPSDDPETQKLNGNEEDYDHHHDEDPESDDENYEYALQIAEMLPFPMVMQTAIELDLLGIIATAGPDRQLSAAEIAAALPAAGNPDAPAMLDRMLYLLATYSVVTCTAVDGGASGGVVRKYGLAPVAKYFVSNEDGVSLGALISLNQGQAFLASWSKLKEAVLEGGIPFNKVHGMDVFHYQGTDPRFNKIFNKAMYGQSTYIIKKIVRRYKGFENIQRLVDVGGGLGHTLRVITSNYPSIKGINFDLPHVIQHAPTIPGVEHVGGDMFESIPNGDAIFMKCILHDWSDEHCLKTLKNCYKALPRKGKVIVVQMNMIEEPQTTPLAKAISQLDVCLMTQSPGGKERTRREFQTLAEAAGFAEFNPVCHVAGFWVMEFLK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 139,
                "End": 386
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 144,
                "End": 384
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 35,
                "End": 141
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 386
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 138
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 163,
                "End": 368
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 139,
                "End": 386
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 45,
                "End": 386
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 43,
                "End": 367
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 144,
                "End": 384
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 140
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MVGATATMVAAARAVATRDPKALIDDPFAEPLVRAVGVDFFTRLASGELDLAEIADDAPGMQRMVDGMAVRTKFFDDFFLDATAAGIRQAVILASGLDSRAYRLPWPAGTTVYEIDQPQVIEFKTATLAGHEPTADRRTVAIDLRDDWPTALQEAGFDPAAPTAWIAEGLLIYLPPEAQDLLFERITALSAPGSRLATEAMPDITHFNAERMKNLGLDFDMSALVYHGERNDPAAWLAEHGWDVTATTVRDLLAGYGRPVPDEDYGAMFGEVAYVSAVLR",
        "response#2": "MARTDGDTWDLASSVGATATMVAAARAVASRDPNALINDPFAEPLVRAVGVDFFARLASGELELDDPTAGAERMQRMADSMAIRTKFFDDFFLDATAAGIRQAVILASGLDSRAYRLRWPAGTVVYEIDQPQVIEFKTATLAGLGAPTADRRTVAIDLRDDWPAALRSAGFDATRPTAWIAEGLLGYLPPEAQDRLFDNITALSAPGSRFATEAMPDITDEETRKRWGFDMSALVYHGERNDAVAWLTGHGWTAEATSRRELFDRYGRPVPEEDDMPESVFISARLTA",
        "response#3": "MRDDTWDLASSVGATATMVAAARAVASRAPNALINDPFAEPLVRAVGVDLFDRLAADEEQADRIGRIADAMAIRTRFFDDYFLNATAAGIRQAVILASGLDARAYRLPWPAGTVVYEIDQPQVIEFKTATLAELGAEPTAVRRTVPIDLRDDWPTALRKAGFDPAEPTAWLAEGLLIYLPPEAQDRLLDNITALSAPGSQLATEALPGISFDDEQTREMAARMRRHGFDLDMADLVYVGERNDVAGYLRTHGWTATPTPVGDLISARL"
    },
    {
        "reference": "MRTTLTGTASVLDTTLTRLIDDVIENGSSFLADDENLQHYKQHLSHLETASKIALLRECLCVRPPLPLLPEDLLQNVDSILTRVRQHKILTPIFSLSPSRLIKHGDLGATRIHLWRGDITTLTGVTAITNAANSQGLGCFQPTHRCIDNIIHAEAGPRLREECFQRMQARGKELEPGEVLVTEGHALFASSVMHTVGPQLKRGASPTETERRQLAKCYESILEALELLPSDEDGSKSIALCCISTGLFAFPADEAAEIAVSTVTSWLQKHPSTTITDVIFNTFTQSDTEFYSKLLGPSHTKSISPVENTPQGSLSLAREWLSSADAVLVTAGAGLSAAEGLDYHSRDLFKRNFPGCLKFGLTSLYSVFGFNDWPSEEHRWGYFFTHLNMVANWSNTPTYQILIPWLRNFGQDAFVRTSNADGLFLANGWPKEQLSTPQGSYGYLQCLNNCRVDAVVPSAPLVADAMPHIDKATQKLMDPSKIPLCRFCGSKMSICVRAGSWFNQAPYQEGEAQWKAWKSRVLREKKNLVILELGVGMNTPGVLRWPNEDLVMRSDGRVKLIRVGMGPEAMVPWEQEDEGLSTCVQGDIGRAIPLLLE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Macro_dom-like, Macro_dom-like sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity,cation binding,hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016798",
                "GO-Name": "hydrolase activity, acting on glycosyl bonds "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0004721",
                "GO-Name": " phosphoprotein phosphatase activity "
            }
        ],
        "go_f_mapped": [
            19,
            183,
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 81,
                "End": 300
            },
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 75,
                "End": 296
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 81,
                "End": 300
            },
            {
                "InterPro-ID": "IPR002589",
                "InterPro-Name": "Macro_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 111,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002589",
                "InterPro-Name": "Macro_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 99,
                "End": 299
            },
            {
                "InterPro-ID": "IPR002589",
                "InterPro-Name": "Macro_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 130,
                "End": 259
            },
            {
                "InterPro-ID": "IPR026590",
                "InterPro-Name": "Ssirtuin_cat_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 307,
                "End": 597
            },
            {
                "InterPro-ID": "IPR029035",
                "InterPro-Name": "DHS-like_NAD/FAD-binding_dom",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 309,
                "End": 596
            },
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 75,
                "End": 296
            }
        ],
        "ipr_mapped": [
            96
        ],
        "response#1": "MKVSYHGHSVVKLETNGKVILVDPFITGNPKTDVDFKDITEKVDYIVLSHGHGDHVGDVVELAKKNGATVIAPFELATYLSSYHGVENVHGMNIGGSHEFDFGKVKFTQAFHGSSFIEEEDKTITYTGMPAGILFQVEEKTIYHSGDTALFSDMKLIGERNQIDVCFLPIGDNFTMGVEDAVLAVEWIQPKTVIPIHYNTFPLIEQDPYQFVEKLAEKGIEGKVLEAGESIQF",
        "response#2": "MTTAAAAAAAAAAAAAAAAAAATAVEERFVRTPDGAPLHCRVHGPAGGPTVLLVHGFGLDGGFWAPLAERLGARFRVIVPDLRGHGRSPAPADPARYRLEDYAADVAAIADAAGAERLWVAGHSMGGTIALLAAERLPRTAGLVLLGAFGVQRERPDGTPAGLTEAERRARCETKARRLATRAGREAAVREAVDFFVADAPEDTRRWLVERWLVCPPEVWAGVWRSWLEHDVADLAARVRVPTLVLHGTRDNLVPIEHGRRLVELLGGPAELVTIEGAGHFPMLERPGETAEALARWLERRAAGR",
        "response#3": "MASKVKITWLGHAAFKIETPSKKVILIDPFITGNPLAKAEDVKPHYILLTHGHGDHVGDAAEIARKTGATIVANYELATWLSSQGAKTIGMGIGGSVLIEDKVKIKMVPAFHSAEQPIGFTIEVEEESVKGEEKKHGEYKYAKKTKRRPGGGGVGKGKAKAKAKYGKQGKVRGPAKPATVLKTVYLGTPAGFVIEAEGKTIYHAGDTAIFSDMKLIGELNKVDVALLPIGDNFTMGIDDAVKAVEYINWFKPKIVVPMHYNTWDLIKQDPEEFKKRVNVGEVWVLKPGESKEW"
    },
    {
        "reference": "MAITDILSAKDIEAALSSCQAAESFNYKSFFSTVGLKGKSADQVKKVFGILDQDKSGFIEEDELQLFLKNFSSSARALTDAETKAFLAAGDTDGDGKIGVDEFQALVKA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            }
        ],
        "go_f_mapped": [
            31
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 78,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 74
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 107
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 91,
                "End": 103
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 52,
                "End": 64
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 71
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 82,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 107
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 78,
                "End": 109
            },
            {
                "InterPro-ID": "IPR008080",
                "InterPro-Name": "Parvalbumin",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 108
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 74
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 107
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 91,
                "End": 103
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 52,
                "End": 64
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 71
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 82,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 107
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MDLRPCLLLCALVSCCLAKPTEKKDKVHESRVHHDPSLDQPLDKLHHDVHDAPLHHDALKHDEDSQNFDYDHDAFLGADEAKTFDQLTPEESKERLGKIVEKIDKDHDGFVTVDELKDWIKYAQKRWIYEDVERQWKGHDLNEDGFVAWDEYKNATYNHDDPTDYKQTLVRDERRFKMADQDSDLIANKEEFTAFLHPEEYDYMKEIVVQEAMEEHDKNGDGFIDLEEYIGDMYSRDNDDYDPEAALGHDEALYDHDAASEEPDWVKTEREQFVEFRDKNKDGKMDKEETKDWILPSYDHAEAEAKHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATFDDF",
        "response#2": "MRIAALVHRLLAVPPTPPPPPPPPPPPPPRRRRRRRRREEEEEEEEEEERLRRVFARFDRDGDGCITAAELAATLAALGLGSEEEAAEEAAAMMAEVDRDGDGRVDFEEFKALYRSGGLLDDDDDDDDEEEEEEEERLRRVFERFDRDGDGCITAAELRATLTALGLGGGGGEEEEEEEAAEEAAAMMAEVDRDGDGRVDFEEFKALYRSGGLLDDDDDDDDEEEEEL",
        "response#3": "LKKALERERARLKKALERERARLKAQLAKAKAELARLKKALERERARLKAQLAKAKAELARLKKALERERARLKKALEEERKRLEAERARLKAQLERERARLKAQLKKALERERARLKKALEEERKRLEAERARLKAQLERERARLKKALEEERKRLEAERARLKAQLERERARLKKALERERARLKAQLERERARLKKALERERARLKAQLERERARLKKALEEERARLARLKKALEEERKRLEAERARLKAQLAKAKAELARLKAQLAKAKAELARLKKALEEERKRLEAERARLKAQLAKAKAELARLKAQLAKAKAELARLKKALEEERKRLEAERARLKAQLAKAKAELARLKKALER"
    },
    {
        "reference": "MSSVLPTPVLPTPGRNINRGHFPDDFIFGAGTSSYQIEGAAREGGRGPSIWDTFTHTHPELIQDGSNGDTAINSYNLYKEDIKIVKLMGLDAYRFSISWPRILPGGSINAGINQEGIKYYNNLIDELLANDIVPYVTLFHWDVPQALQDQYDGFLSDKIVDDFRDFAELCFWEFGDRVKNWITINEPQSYSDFFGVAYDTPPKAHALKASRLLVPTTVARPSKPVRVFASTADPGTTTADQVYKVGHNLLLAHAAAIQVYRDKFQNTQEGTFGMALVTQWMKPLNENNPADVEAASRAFDFKFGWFMQPLITGEYPKSMRQLLGPRLREFTPDQKKLLIGSYDYVGVNYYTATYVSSAQPPHDKKKAVFHTDGNFYTTDSKDGVLIGPLAGPAWLNIVPEGIYHVLHDIKENYEDPVIYITENGVYEVNDTAKTLSEARVDTTRLHYLQDHLSKVLEARHQGVRVQGYLVWSLMDNWELRAGYTSRFGLIHVDYYNNFARYPKDSAIWFRNAFHKRLRIHVNKARPQEDDGAFDTPRKRLRKY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008422",
                "GO-Name": "beta-glucosidase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 511
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 511
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 515
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 232,
                "End": 514
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 195
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 462,
                "End": 479
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 341,
                "End": 355
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 486,
                "End": 498
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 426
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 441,
                "End": 452
            },
            {
                "InterPro-ID": "IPR033132",
                "InterPro-Name": "Glyco_hydro_1_N_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 26,
                "End": 40
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "MARKVARKVARKVARKVARKVARKKVARKVARKVARKVARKVARKVARKVARKVARKEKQKQKEKQKQKEKQKQKEKQKQKEKQKQKEKQKQKEKQKQKEKQKQKEKQKQKEKQKQKEKQKEKQKQKEKQENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKKKKKKKKKKKKKKKKKKKKKKKKQEEEQQEEEEQQEEEEQQEEEEQQEEEQQEEEQQEEEQQEQEEQEEQEQEQEEQEEQEQEQEEQEEQEQEQEEQEEQEQEQEQEEQEEQEQEQEQEQEQEQEEQEEQEQEQEQEQEQEQEQEEQEEQEQEQEEQE",
        "response#2": "MTDAESADPERAAFGRRVAALRRAAGLTQEELAERLGVSGQAVSKWERGVSFPDLASLVALARALGTTTDALLGLDADADADADADADADAEGSGSGSGSGSGSASGSRSGSGSGSGSGGGSGSGSGGGGGSGSGSGSRPGSRPGSRPGSRPGSRPGSRPGSGPGSRPGSRPGPRPAPRPAPAPRPRPAPRPAPRPAPRPAAPRPAAPRPAAPPRRPRPRPRPPRPRPRPRPPPPRRRPRPRPPPRRRPPPRRRRPPRPRPPPRPRRRPPRPPPGPRRRLPP",
        "response#3": "SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSSSSSSSSSSSSSSSSPPSSSSSSSSSSSSSSSSDDDDDDDDDDDDDDDDDDDDDDDDDDDRHHHHHDDDDDDDDDDDHHHHHHHDDTTTSTTTDDDDDDDDDDDDDEEEEEEEEKEKEKEKEKEKEKKEKEKEKEKEKEKEKEKEKEEEKEKEKEKEKEKEKEKEKEKEKEKEKKEKKEKKEKKEKEKKEKEKKEEEKKEKKEKEKKEKEKKEKKEKEKKEKKEKEKKEEK"
    },
    {
        "reference": "MSSVLPTPVLPTPGRNINRGHFPDDFIFGAGTSSYQIEGAAREGGRGPSIWDTFTHTHPELIQDGSNGDTAINSYNLYKEDIKIVKLMGLDAYRFSISWPRILPGGSINAGINQEGIKYYNNLIDELLANDIVPYVTLFHWDVPQALQDQYDGFLSDKIVDDFRDFAELCFWEFGDRVKNWITINEPESYSNFFGVAYDTPPKAHALKASRLLVPTTVARPSKPVRVFASTADPGTTTADQVYKVGHNLLLAHAAAIQVYRDKFQNTQEGTFGMALVTQWMKPLNENNPADVEAASRAFDFKFGWFMQPLITGEYPKSMRQLLGPRLREFTPDQKKLLIGSYDYVGVNYYTATYVSSAQPPHDKKKAVFHTDGNFYTTDSKDGVLIGPLAGPAWLNIVPEGIYHVLHDIKENYEDPVIYITENGVYEVNDTAKTLSEARVDTTRLHYLQDHLSKVLEARHQGVRVQGYLVWSLMDNWELRAGYTSRFGLIHVDYYNNFARYPKDSAIWFRNAFHKRLRIHVNKARPQEDDGAFDTPRKRLRKY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008422",
                "GO-Name": "beta-glucosidase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 511
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 515
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 232,
                "End": 514
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 201
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 511
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 462,
                "End": 479
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 341,
                "End": 355
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 486,
                "End": 498
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 426
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 441,
                "End": 452
            },
            {
                "InterPro-ID": "IPR033132",
                "InterPro-Name": "Glyco_hydro_1_N_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 26,
                "End": 40
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "MKFGFVTAGMKGTYLEKFKKAKELGFDGVELMFWDPPTEGKEYPSKYLEDDAHRQEVLDAIKESGLEVVSLSVHAIVDQENFDKYIEELKKVADFAKENNIKLSVEVLNPHEDRKDYPRFGSTPEEMIKVVEAVGRDNVGLLYDIYHHQIIKGTNEDLEKLLPYVTHFHTANNKLGRDVDIEDGEINYKYIAKLFKKHNYEGYVSGEFIPKGEPEEGLEKFKANFETEEEKEAKKAAKKAEKEAKKAAKKAEKEAKKAEKEAKKAAKKAAKEEAAAEEAAAEEAVAEEAAAEEAAEEAAEEAAEEAAAEEAAAEEAAAEEAAAEEAAAEEAAEEAK",
        "response#2": "MKKELLKINYKKRIIHNKRINIPYGLRENGEIVHISEVERGKKCNCYCPGCKEKLVARKGDIKEHHFAHEANSECSPETYLHKLAKQIITEMKEIELTFPKYKEKIKKKCKDCKEKESEIILEPGKFIFDKAIQEYKIDDIIADVYCEKNNHKLIIEVAVTHFVDEIKREKLKENNISAIEIDLSNLRKEDWNIEKLKETILNKDYKKWIYNPYEEQEKLKLEQEKLKKIQLKLKEEQEKLKLEQEKLKEEQLKLKLYQEKLKEIQLKLKEEQEKLKLEQEKLKEEQLKLKLEQEKQEKLKLEQEKLKEEQEKEKEKLKEEQEKLKELQEKLKSEQEKQEKLKLELQLKLKLEQEKLKELQEKLKELQEKLKSEQEKLKEEQEKLKEEQEKL",
        "response#3": "MDLLVRGGTVLDGTGAAPRPRADVLLRDGRVAAVGPDLDVPPGAEVVDAAGGVVLPGFVDAHAHLTDPEQLRFAAAAGVTTVLDMGSRPDAVAAAREAARTTRLLAFLNVSEGARPGGRPVDREALRAAAARPEVLGVKVRLSAGVTDTGLAAVDEALALADETGRPLMVHLSDPPEGVAELLPRLRPGDLLTHCFTSKWPLLADGRVRPAVRAARERGVTFDVGHGRGSFSFDVARAALAEGFRPDVVSTDLHTGNVDGPAYDLPVTVSKLLALGVPLVDAVRAATLAPARAVGLADRVGSLAPGARADVAVLAVEEGDQVEFHDVHGTVVGAARRLRPVLTVLDGRVVARDGRVVPAPPPPAAPAPPPPSSPPSR"
    },
    {
        "reference": "MGSLDIKQESSPLMTNPLDSEEFRRQGYMVIDFLAEYYKNIQKFPVRSQVEPGYLRKRLPESAPYEPESIETILKDVHDDIVPGLTHWQSPNYYAYFPSSGSTAGLLGETLAAGFNVVGFNWISSPASTELESIVMDWLAEMLNLPKSFTFSGDGGGVMMGTTCEAILTTITAARDRILDRIGREHINKLVVYGSDQTHCSFFKSAKIAGISPNNFRQVKTSRVNAFSMRPDALRAAIQADVDAGLVPFFLCTTVGTTSTAAVDPVALLCEVAKDYGMWVHIDAAYAGNACICPEFRHMINGVENADSFSFNAHKWFLTTLDCCCLWVKDPSSLVRCLSTNPEYLKNKATDTQQVVDYKDWQITLSRRFRSLKMWLVLRSYGVDYLRNFLRSHVDMAAYFEQLVRMDGRFEVVVPRSFALVCFRLSASAVIQRLYDSCHRHGHGQKFLEEETLNDVNAELLESVNSAGQIYMTHSLVDGVYMLRFAVGATLTQTHHVTYAWKQVQDHASAVLARRINSICNC",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within PyrdxlP-dep_Trfase_small, PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_major sharing conserved structural features; 2. The protein must be able to perform the lyase activity,pyridoxal phosphate binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016831",
                "GO-Name": "carboxy-lyase activity "
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": " pyridoxal phosphate binding "
            }
        ],
        "go_f_mapped": [
            32,
            33
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 392,
                "End": 520
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 508
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 100,
                "End": 391
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002129",
                "InterPro-Name": "PyrdxlP-dep_de-COase",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 425
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 392,
                "End": 520
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 130,
                "End": 149
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 42
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 407,
                "End": 426
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 111,
                "End": 129
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 83
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 46,
                "End": 63
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 109
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 155,
                "End": 175
            },
            {
                "InterPro-ID": "IPR010977",
                "InterPro-Name": "Aromatic_deC",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 379
            },
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 508
            },
            {
                "InterPro-ID": "IPR021115",
                "InterPro-Name": "Pyridoxal-P_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 308,
                "End": 329
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 100,
                "End": 391
            }
        ],
        "ipr_mapped": [
            73,
            74,
            75
        ],
        "response#1": "MTPPPPPPPPPPPPPPPQPPVPSPRLVPCLDVRDGRVVKAGGLRDAGDPVALARAYADDGADELALLDVTASARDDRRPLVDLVAATVAASPVPVTAGGGVRTVDDADALLDAGADKVSVNSAAVADPAALAALAARATARGAAVVVAVDARPDPERGGRWRVVTGGGRTDTGLDAVTWARRAAALGAGELVLNSVDADGTRAGYDLPLLRAVRDASPVPVIASGGAGTPEHFAAALDAGADGVLAASVLHAGPVPLAELKAAIAAHRRPTPPPAPR",
        "response#2": "MTDLLRPAVRALRPYAPARSGDPGLPAGAVLLDANENPHGPGLNRYPDPQPAELREALAAYLGVPADRLLCGNGSDELIDLAVRALAGPGDEVLLPAPTFGMYRASAAAAGATVREVPLRDDLSWDVDALTAAVGPRTRIVFACTPNNPTGSRAPVPDLARVADAVPAVLVLDEAYQAFTEEPAPVPERPHVLRTRTFSKFGLAGLRVGALAGPAALVEAADALRPPYNVNALAAAAALAALREAPAELARRAEAVRAERARLTAGLAELGAEPLPSQANFALLRFPDPARAAEATAALARERILVRDFAEPGWVRVTTGRPEDNDAALAALARQLAPAPA",
        "response#3": "MESPYGNPGTNRYGGSEETRRLEEEAREALKEVFGAEEGEAIFTGSGSEANFLAVKALLEEGETVLVPRYSGHTLTAELAGAEPVEVREDLTPDLEALREALEERRPKALVLSYVNTYTGLKLPLEEARSLAEEADAFFHVDAAQMAGVVERDPLEEGADVLTFTAHKGLRGPRGGAVLARREVLERLREENPYRRGGPPLHNIAAAKRALELARENPEFEEKRRRVRERAEWLRERLEEEGFEVLPSETNMVTFRVGDEETARRAKRELEERGFLVNLFPSPFGVEEPALRATVTEAHEEEELEALAEALAEVRERGPSP"
    },
    {
        "reference": "MSKPAAAAPSDPSKPSKPLKEVPGSYGLPVLGAVKDRLDFYWFQGDTEFFRIRMEQHKSTVFRVNYSPGPPGYPDSRGIILLDQKSFSVLLDNSKVDKSDTLLGPYIPNLAFTGGYRVLPYLDTSEAKHTAYKDLIFELLHVNSSRIIPEYNKVFAETAGSWEERIAKSGKAEVFASSDSMITKFLLRTIVHKDPAEPGPASLGPKFRDTYQLWTGVNFAGIAHTPLPHFLEELLFHTFRLPPFLVKKQYKALANFYRTHATEVLDLAEKKYGLDREETVHQLILILGINARLGLHKMIPALIYYLGLLGEDFQAKIAAEVRSAVHKNRAQGEEGVNITTQALLEMPLLRSTVLETLRLTPSIFYIYGRAREDMVIESHDAAFQIKKGELLGGHQYFVMRDPEVFEEPHKFVADRFLGERGKAVLPYLVWSNGRETESPSSSNKQCPAKDVAELITMQFVAEMFLRYDSFEITKDSFINTTELNVHLKSLKKRSV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein must be able to perform the heme binding,lyase activity,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0016836",
                "GO-Name": " hydro-lyase activity "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            32,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 495
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 312,
                "End": 434
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 479
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 399,
                "End": 417
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 362
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 495
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 312,
                "End": 434
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 479
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 399,
                "End": 417
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 362
            }
        ],
        "ipr_mapped": [
            18,
            21,
            22
        ],
        "response#1": "HLVAQMSSRIFLGPELCRNESWLKITVDYTVNVFTAVAELRLWPEFLRPIVHWFLPSCRQLRAQIAEAREIINPVIERRRREKAQAKAEGREVPEKYNDTIEWFDEVAGGSEYDPALAQLQLSVAAIHTTSDLLTQVLFDLCANPELIQPLREEIVRVIRENGGWKKTALYNLKLMDSVLKESQRLKPVVRLSMFRKVVKDGMKLSDGTYLPKGTHISVSAHAMGRDESIYPDPEKFDGYRFVRLREVPGQENSAQLVSTSPDHLGFGHGKHACPGRFFASNEVKIALCHILLKYDVRFEDGAKPRIMNSGIIFAADPSAKVMIRRREV",
        "response#2": "MLHIVAQMSSRVFLGLPLCRNEEWLRITVNYTVNVVQAGIRIFPEILRPVVHWFLPSCRKLRAQVAEARRIINPILEERRRAKEAAKKEGREPYNDTIEWFDEVAKGSEYDPAVAQLSLSVAAIHTTSDLLTQVMFDLCTNPELIQPLREEVIQVLREEGLSGGKDGIKKTALYKLKLMDSVLKESQRLKPISVVTMNRMVKEDVKLSDGTFIPKGTRISVPAHAMHHDPAIYNDPEKFDGYRFVDQRDSAQFVSTSPDHLGFGHGKHACPGRFFAANEVKIALCHILLKYDFKFVDGQKRPENLTFGNEVMVDPSARIVVKRRKEEITL",
        "response#3": "MLPPPSSAFNSDLSIVLITRDVVRTQLTQAINRLTRPLSEETSHVLTTEWTDNPEWHEVNLHQTILRMVARLSSRVFLGLPLCRNEGWLKITTDYTVNVFTAARELNIFPDFLRPVVHWFLPSCRKLRAQIAEAREIINPVLEERRRVKEEARMRGEEVPQYNDTIEWFDEVAKGSEYDPALAQLRLSVAAIHTTSDLLTQVMFDLCAHPELIQPLREEVVRVVRENGWKKTALYNLKLMDSVLKESQRLKPVGVVTMRRYAMKDVKLSDGTVIPKGAPVAVSAHHMWNDPSIYPDPEKFDGYRFVRMREVPGQENSAQLVSTSPDHLGFGHGKHACPGRFFASNEVKIALCHILLKYDIKFCDGEKPRVINSGIFITADPAAKIMVRRRKEEISL"
    },
    {
        "reference": "MSSADVAATIVRLYESAVEAHPDKPVINDGHRVWSYRELNSAANRIAWWLIGRGVGPEQTVGVALDRGIDQIAALLGTLKAGAVYLPLDPVLPAERINYLLADATPSLILDGDAAASAGQPEDTPAVPLTSDSLAYVIYTSGSTGTPKGVGVTHGSMVNLARTVTGQYALGDTPRVLQLASLGFDVAIWELLTAVATGGTLVVSQADQLSGDDLLRVLREQRITHVTLPVPVLASLPPDAENQLPDLTTVHIGGETCPPELVRRWSAGRRLINGYGATETTVAATLTPPLTGPDAPIGKAIDGTRVYVLDDTLAQVVLGAAGELYVAGANVARGYLRRPGLTASRFLADPYGPPGSRMYRTGDVGLIRPDGQLEFLRRADDQVKIRGARVEPGELEAVLQRRTDVVHAAVTVRPDARGERQLVAYVVPAAAATGAAELRDDLRGTLPSYLVPSSVVLLDSLPLTPNGKVDRDALPDPEYAPAGLDRTARSPLEDMLRVVFAEILELPQVGFDDDFFDLGGHSLLAGRLIGRIRGTLGLEVHMKDFFEKSTPAALASYLQRQETGPARPELTRLPRPDRIPLSFAQQRLWFLHRLEGPSATYNMPLALHLTGKVDTGALAAALTDVIRRHEPLRTLIREVDGQPYQQILDPEEVRPALPVRQVGAAQLDEELRRSARHEFDLARQIPVRAELLTVSPDESVLMLVIHHIAGDGWSGAPLARDLVTAHSARLTGVAPQWPPLPVQYADYTLWQRAMLGGEEEPASPLNEQLRYWREQLADLPHEITVPGDRPRPAVATYRGGVVPITMDADLHAGITELARRNGATVYMVLQSTVTALLTRLGAGTDVAIGAGVAGRSEPALDDLVGLFVNMLVLRTDTAGSPRFTELLQQVRDTSLGAYGHQDIPFEQLVESLNPHRVAGRQSLFQVALVLQNNTSVPFDLPGLRVRAEQIPTGTARFDLSLSVTEHGDGISGTVEYAADLYDRATAEAVVERWIQLIRQVVADPARRVDTLDVTTPGDESRLAGWRRYERDVPPVTFGDLFARQVAATPDAIAVSDGGDVWTYREVNRYANHVADRLIDRGIGPEDFVAVAMPRSARLVASLLGVLKAGAAYVPVDLVFPARRNRHVIIDSNPRLVLTSRAGAENLPADLPCELVMIDAWGTGREDGPADADRVRPSNVDSPAYVIYTSGSTGQPKGVVVTHRGLAAFAETLRERCAAGPNDRVLQLSSPSVDASVLEMVWAFSSGARLVIASQYRLAGEELAQALAEQRITHAHIPPSALSTIPAEAAGRLPEFRRLSVGAESCPSELVRLWLPGRDFVNAYGPTECTVAASHTFPLAEARAPIGRPVIDAELYVLDETLRPAAPGVPGELYIGGAGLARGYLRRGGLTASRFVANPYGEPGSRVYRTGDVVRWNTDGELEYLGRSDEQVKVRGFRVEPGEVERVLASQPSVDRAVVVPRRDRSGAVSLAAYVVLAAASPAGFDDQLSEWNDIYDQVYAGFSGDAGNDFIGWTSSFTGGPIPIEEMREWQRSAVDAVRRFGRGRVLEIGSGSGLLMTPLADAVDEYWGTDLSEISIDRLRAFADARRWNHVRLSCQPAHDVSGLPRRYFDTVVINSVVQYFPSADYLRDVLAKVVDLLADGGRVIVGDVRHYGLLRVFHAAVHDFRGTEGLRAAVEHAMAVEKELLLAPEFFTSIDHPAVTGVEVTLKAGQASNELTGYRYEVVLHTAPARRLTTLPVLVWGRDTTDLDEVTGPARVTGIPNPRLAGGVAAVRLLDGMDAVPPAAGPELESEAVRRWAVQRGMRAVPTWSSNRWNTYDVVLIHAAEAEPLADVYRPADGVEPANVPEVARTAGKLVSELRSTVQGLLPDYMVPATITPIERIPVTPNGKIDRRALPDPEVVLSRGRHARTPLEQILCELYADILGLERVGVDDSFFDRGGHSLLATRLTSRIRSVLGVEALLQQVFAAPSPAELAVVLSEQQGRVQQALEPVARPEVLPLSFAQQRLWFLHKLEGPSATYNSPLALRLSGTLEVTALRAALGDVVGRHEALRTVFAETDGVPYQKVLDVADVDLSVREVAADELPGVLRDAARYEFDLAREIPVRAWLFAAGPGEWVLMLVLHHIAADGWSLGPLARDLATAYADRRMGRGPSWSPLPVQYADYTLWQRRLLGDEADPDSVFGRQLAYWRGQLAGLPQQVTLPTDRPRPQTASYAGDVTMFRLDAGLHADLLRLARTSGATLFMVLQAALVAVLTRLGAGDDVPLGSPIAGRSDDGLDDLVGFFVNTLVLRADTSGNPGFDELLERVRDTSLEAYAHQDVPFEFLVEKLNPHRSTAHSPLFQVLLAFQNNSDTSFHLPGLRAEREEIGTRVSRVDLTLNITEAFGVNGAPQGIRGAVEYATDLYDARTVESFAARFVRMLQAAVADPSRRINAVDLLSDEENATVLALSGRDAAVPESRVWPAVFEATAAAAPDATAVVEGQLSWTYAQLNANANRLARYLIDRGVGPEDVVGVLMPRSAMQIATVLAIGKAGAAFLPIDPAYPAERVEYLIADARPKMLLADTAHVGVAAGAIAIDEPAVATALREAPVTDPAGVAVRLEHPAYVIYTSGSTGRPKGTIVTHSGLAALAVSGCERAAVDRDSRVLQLTSPSFDVSVFEFLAAFHAGAVLVMPEPGRLAGEELAELLADAGVSHAFVPPSVLATLPDEAPGRLAGLRSLVVGGEACSADLVRRWSVGRRMTNLYGPTETTVAASISRPMSTGAHPIGAPLPGTRVYVLDANLRPVPPGARGELYISGIGVARGYLGRPVLTASRFVADPFGPAGARAYRTGDVVRWNADGELEYFGRSDHQLKIRGFRVEPGEIEAALVRRPSVAQAVVVARPDQHGFQALYAYVTAGAEPADAARLREELRAELPDYLVPAAIVVLDEFPLNANGKLDRNALPEPRFVTSAADIRSPGMPQEEILRSVFADVLGIERISADDNFFDLGGHSLLVTRLISRVRGTLGVDVSMQTFFNAPTPRQLAGQLLEGGPVPARLQPVPRPEALPLSFAQQRLWFLHKLEGPSATYNSPLAIKLSGELDVDALRLALADVVVRHEALRTVFAERAGNPYQRILDSAEVELPVREVPQSKLPDALREAARYEFDLAREIPLRAWLFTAGPGEWVLMLALHHVVADGWSLQVLVSNLTAAYTSRRAGHAPSWQPLPVQYADYTLWQRRHLGTEDDPDSVSSRQVSYWLEQLADLPDQVTLPTDRPRPAVASYRGETVTFDLDAEEHAELVRLARETGTTLFMILQAALAGLLTRLGAGTDIAIGSPIAGRTDDRLENLIGLFVNMLVLRTDTGGDPTLGELLTRVRETSLAAYAHQHMPFEYLVERLNPHRSAAHHPLVQILFGLQNTAEQNVSLPGVTASGMSVDTGVSRVDLSINIVEASAPDGSPAGLTGLVEFSTDLYDRATVEAFAARWVRVLRAMVVAPGSRLSGVQLLGADERVRLLQRWGAASGPVAAVTLAELFERRVAARPDAVAVVEGEVSWSYARLNAYANRVAWSLVERGVGVEDVVAVVLPRGAVQVATVLGVVKAGAAYLPVDPSYPRARVEYLLQDAGPALVIGESDVFDGQPEHDPVRPVPVDAAAYVIYTSGSTGQPKGVVVTHRGLASMAATQQRLGAGEGSRVLQFAALGFDATVWELVMALGAGAALVVPKTDQLAGEDLAAVLREQRITHLTLPPTVLATVPADRLPDLGTLVVAGEACPPELTARWSPGRRMFNAYGPTESTVCASISAELSPGLAPIGGPVLNTRLYVLDDALQPAASGVPGELYIAGEGLARGYRGRAGLTATRILADPYGPVGSRMYRTGDVVRWNADGDLEYLGRSDEQVKIRGFRVEPGEVASVLLRHPAVAQAAVIVRLEQLLAYAVPALGRAVRDGELRAYLQDELPEHTVPSAVVLLDEIPRTSHGKVDQRALPDPEQAGGRGRAPRTPQEELLCVLFAQVLDVQQVGPDDSFFDLGGHSLLATRLIIRIRRAFRCELPPRALFAAPSPAELAVVLSEQQGRVQQALEPVARPEVLPLSFAQQRLWFLHKLEGPSATYNSPLALRLSGTLEVTALRAALGDVVGRHEALRTVFAETDGVPYQKVLDVADVDLSVREVAADELPGVLRDAARYEFDLAREIPVRAWLFAAGPGEWVLMLVLHHIAADGWSLGPLARDLATAYADRRMGRGPSWSPLPVQYADYTLWQRRLLGDEADPDSVFGRQLAYWRGQLAGLPQQVTLPTDRPRPQTASYAGDVTMFRLDAGLHADLLRLARTSGATLFMVLQAALVAVLTRLGAGDDVPLGSPIAGRSDDGLDDLVGFFVNTLVLRADTSGNPGFDELLERVRDTSLEAYAHQDVPFEFLVEKLNPHRSTAHSPLFQVLLAFQNNSDTSFHLPGLRTRLEGVSTGLSRVDLFISLAEQPDAGGVIGAVEYATDLYDAATVEAFVGRWLRFLAAVAHDPEQRIGSVDLLLDGERERLTGWAYTEPEVEPATLSELFERRVAARPDAVAVVEGEVSWSYARLNAYANRVAWSLVERGVGVEDVVAVVLPRGAVQVATVLGVVKAGAAYLPVDPSYPRARVEYLLQDAGPALVIGESDVFDGQPEHDPVRPVPVDAAAYVIYTSGSTGQPKGVVVTHRGLAALATGTVGRNAVAGDSRVLLLASPSFDASVLELMIAIGAGAALVVSRESRLAGEELATLIAQARVTHAFVPPSVLATLPGAATGELPAFQGLVVGGEACSPDLVRRWSAGRRMTNLYGPTETTVATTVSRPLFGEAHPIGAPLPGWRVYVLDAGLHLVPPGSRGELYIGGVGLTRGYLRRAGLTASRFVADPFGPAGARMYRTGDVVRWNADGELEYLGRSDHQVQIRGIRVEPGEVQAALTAHPDVARAVVVVSDDRRGDPALVGYMVPERPGADPAAVREDLRRILPDHLVPVAIVVLPEIPLTPNGKLDRDALPDPEYETSRGREPRTPEEEILCGLFTEVLGLKQVGAEDDFFDLGGHSLLGTRLISGIRAKLGFEVRLLTLFEASTPAALARAMLEANAPARTALEPMPRPELLPLSFAQQRLWFLHKLEGPSPTYNMPLTLQLSGPLDVPALRAALTDVVGRHEALRTVFAEHDGQAYQRILDPVEIELPVHDAASDEALQAAARHRFDLAGEIPLRVSLYAAGPGEWVLMLVLHHIVADGWSLRPLARDLATAYAARTAGRAPDWAPPPVQYADYTLWHRELLGDDADPDSAFGRQLAFWRDRLADLPEQVTLPTDRPRPRVASYRGDVSTFQVDAELHAGLMALARQTGSTLFMVLQTALSALLTRSGAGTDVVVGAGVAGRTDERLDDLVGFFVNMVVLRTDTSDDPTFVELLQRVRASSLAAYAHQDIPFEYLVEKINPLRSASHQSLFQIAMVLQNNAEADFDLSGVRVWQEGRGTGTSRFDLSLSLTETTTADGRPTGVTGVVEFSTDLYDRATVEAFAARWVRVLRAMVVAPGSRLSGVQLLGADERVRLLQRWGAASGPVAAVTLAELFERRVAARPDAVAVVEGEVSWSYARLNAYANRVAWSLVERGVGVEDVVAVVLPRGAVQVATVLGVVKAGAAYLPVDPSYPRARVEYLLQDAGPALVIGESDVFDGQPEHDPVRPVPVDAAAYVIYTSGSTGQPKGVVVTHRGLSGLAATLRQRCAADVDSRILQASSPSFDAAVLELVWAWDSGAALVIASADRLAGDELARALADHRITHALIPPSVLSTLAADAPRTLTDFRTLIVGAEACPPELLRRWAPGRRMVNAYGPTEATVVASQTGELHEPPVSIGKPALGTRLYVLDERLGLAAPGVPGELYIAGAGVARGYRTRPSLTASRFLADPYGPAGTRMYRTGDLVRWNADGDLEYLGRSDEQVKIRGFRVEPGEVERVLAAQPSVARAVVVPRPDRSGAVSLAAYVVLADQGSATDFDDQLDEWRSIYHEVYSGLAREPGTDFAGWNSSFTGTPIPIEQMREWQRSAVEQVARFGPRRVLEIGAGSGLLMVPLIERTEEYWATDFSAAAVERLREYARERGWEHAHLRCQPAHDMWGLPRSHFDTIVLNSVVQYFPSTDYLRDVLGKALDLLADGGRLVVGDVRHHGLLRAMHTAVQEFRNPGSGSSAVDHAVAIEKELLLAPEFFTAFRHPRATGVEVLLKRGSADNELTAYRYEVVLHTGATRPVGDLPELVWGHDVTDLADVTAPARLTRIPNPRLVGINEPRLHPEQVRRWAAERSWRAVPTWSPRNWDGYDVVLLAADEDEALTDVYRPGTPEVVANVPAVARTAGEHVSELRGTIKSLLPDHMVPATITPIERIPLTPNGKIDRRALPEPEIVTTTTEERGPRDPYEEILCELYADLLGLPRVGVDESFFDLGGHSLLATRLTSRIRAVLGIEVPLQQVFAASTPAQLAAVLAQGSGRAGPALEPAPRPEVLPLSFAQQRLWFMQNLEGASATYNSPLAVRLSGALDVAAMRAALGDVLARHEVLRTVFGERRGEPYQRILDAVEIDLPVRAVAEGDLTQVLRDASRHEFDLSREIPVRASLFNTGRDEWVLLLVVHHVAVDGWSMRPLTRDLTTAYEQRAAGRVPDWAPLRVQYADFALWQHRMLGDEADPDSRLSRQLAYWRDQLAGLPRLVTLPADRPRPDEASHRGAMLTRNLDADLHQALRVLARRHGSTLFMALQAALGAQLSRSGAGTDIPVGAPIAGRADDALEDLVGFFINTLVLRIDTSGRPSFTRLLKQVRETSLAAYAHQDVPFDHLVEKLNPDRSPGQHPLFQVQLVLQNTPDAEFELAGLTARPQLDGVETGVSRVDLSVNAIETFDDHGLPAGLILVVEYATDLYDSATVDAFLDEFGQLLHEVADSPDQPIGGLELDNIAAPVPGTLPQLFETWAAATPSAIAVTDGAADMTYAELNSRANRMARALIDRGAGPEDLVAVLLPRSVRQVATILAIAKSGAAYLPIDPTYPADRVAYLCADALPKLIVTDAAGSARLGADQPVIDVDDPATVAQWESRPDTDPTDRDRTTALGLDHPAYVIYTSGSTGRPKGAVITQAGLAGAAEAWVQRWGFEPGSRVLQLSSPSFDASIMDFIVAFAAQGTLVLPEPGLIAGEALARVLTEKRITHLVTLPSVLASMPVDVAGRLTGLRGLLLGGEVLTPDLAARWSPGRRMINVYGQTETTVACTMTDPLAGERVTVGRPIPGTRVYVLDALLRVVPPGTDGELYVAGPAVGRGYLHRAGLTASRFVADPYGPPGSRMYRTGDLGRLNYAFELEYAGRTDEQVKIRGMRVEPGEVEAALAEHPAVARAAVAVRADRQGDLALFGYVIPVQAGADVSGIREDLRRSLPEHLVPAVMTAMTDFPLTPNGKVDRDALPAPQVTAPVGRGPRTPQEEILCGLFAELLGLGQIGVEDNFFDLGGHSLLANKLIARIAEVMGTEIPIRTFFAGPTVAQLAEQLGSDGTDRAFDVLLPLRTGGTLPPLFCIHPGAAICWSYADLLLHLSPDFPVYGLQSPALSHPDELPETLIQVADDCIEEMRQVQKTGPYYLLGQSFGGVVAHAMAARLEAAGEQVGLIVALDSEPSRSLSEHEQAQVIEATAKVYTGILEVLGVDPAALPSGNLTFAQFSELARTTNTLLGNVAEDEFHLLMAILHGNISIATRHRSERVDADMLIFGAAEERERVLDPEVWREFVGGEITYHPIPTSHSTIMAPEALQVIGPILEQHLRAVIAGNATTKEEN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PP-bd_ACP, PP-bd_ACP, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PKS_PP-bd, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP, PP-bd_ACP that are essential for its biological function; 2. The protein should be classified within ACP-like_sf, AB_hydrolase_fold, SAM-dependent_MTases_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, AB_hydrolase_fold, SAM-dependent_MTases_sf, SAM-dependent_MTases_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, ACP-like_sf, SAM-dependent_MTases_sf, ACP-like_sf sharing conserved structural features; 3. The protein should contain Ppantetheine_attach_site, Ppantetheine_attach_site, Ppantetheine_attach_site, Ppantetheine_attach_site that allow regulation through chemical modifications; 4. The protein must be able to perform the phosphopantetheine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0031177",
                "GO-Name": "phosphopantetheine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003824",
                "GO-Name": "catalytic activity "
            },
            {
                "GO-ID": "GO:0031177",
                "GO-Name": " phosphopantetheine binding "
            }
        ],
        "go_f_mapped": [
            24
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6390,
                "End": 6461
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7428,
                "End": 7773
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 5032,
                "End": 5047
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1908,
                "End": 1983
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6004,
                "End": 6173
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 6419,
                "End": 6434
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7432,
                "End": 7507
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6383,
                "End": 6465
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1905,
                "End": 1986
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 482,
                "End": 564
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4998,
                "End": 5078
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3984,
                "End": 4053
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1914,
                "End": 1983
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 493,
                "End": 562
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 7438,
                "End": 7507
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5008,
                "End": 5077
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 6395,
                "End": 6464
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2964,
                "End": 3033
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3986,
                "End": 4046
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2966,
                "End": 3027
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1916,
                "End": 1976
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5010,
                "End": 5072
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7440,
                "End": 7502
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 6397,
                "End": 6459
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 496,
                "End": 558
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7432,
                "End": 7503
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3977,
                "End": 4049
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 6389,
                "End": 6464
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7506,
                "End": 7771
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1524,
                "End": 1685
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6016,
                "End": 6168
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2958,
                "End": 3033
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 7462,
                "End": 7477
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1909,
                "End": 1979
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3978,
                "End": 4053
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 489,
                "End": 592
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5001,
                "End": 5073
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2988,
                "End": 3003
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5002,
                "End": 5077
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2951,
                "End": 3033
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3970,
                "End": 4059
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 487,
                "End": 562
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1490,
                "End": 1670
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2964,
                "End": 3061
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6390,
                "End": 6461
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7428,
                "End": 7773
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5094,
                "End": 5458
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 5032,
                "End": 5047
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 2607,
                "End": 2618
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1428,
                "End": 1501
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5922,
                "End": 5995
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1908,
                "End": 1983
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6004,
                "End": 6173
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 6419,
                "End": 6434
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2487,
                "End": 2880
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3536,
                "End": 3906
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1062,
                "End": 1458
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4552,
                "End": 4926
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 35,
                "End": 410
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 6956,
                "End": 7356
            },
            {
                "InterPro-ID": "IPR010071",
                "InterPro-Name": "AA_adenyl_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 5578,
                "End": 5952
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7432,
                "End": 7507
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6383,
                "End": 6465
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1905,
                "End": 1986
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 482,
                "End": 564
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4998,
                "End": 5078
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 380,
                "End": 481
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7326,
                "End": 7427
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4896,
                "End": 4997
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 3984,
                "End": 4053
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 1914,
                "End": 1983
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 493,
                "End": 562
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 7438,
                "End": 7507
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 5008,
                "End": 5077
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 6395,
                "End": 6464
            },
            {
                "InterPro-ID": "IPR020806",
                "InterPro-Name": "PKS_PP-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 2964,
                "End": 3033
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3876,
                "End": 3969
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 7083,
                "End": 7094
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 1185,
                "End": 1196
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 580,
                "End": 952
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 4653,
                "End": 4664
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3986,
                "End": 4046
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2966,
                "End": 3027
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 1916,
                "End": 1976
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5010,
                "End": 5072
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 7440,
                "End": 7502
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 6397,
                "End": 6459
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 496,
                "End": 558
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 4068,
                "End": 4512
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 3048,
                "End": 3495
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 5093,
                "End": 5537
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 578,
                "End": 1020
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 6479,
                "End": 6919
            },
            {
                "InterPro-ID": "IPR001242",
                "InterPro-Name": "Condensatn",
                "InterPro-Type": "DOMAIN",
                "Beg": 1998,
                "End": 2445
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7432,
                "End": 7503
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4070,
                "End": 4440
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3977,
                "End": 4049
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 5679,
                "End": 5690
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 6389,
                "End": 6464
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2000,
                "End": 2369
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7506,
                "End": 7771
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3049,
                "End": 3419
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1524,
                "End": 1685
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6016,
                "End": 6168
            },
            {
                "InterPro-ID": "IPR023213",
                "InterPro-Name": "CAT-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6481,
                "End": 6853
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 6935,
                "End": 7282
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 5557,
                "End": 5877
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 1041,
                "End": 1384
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 336
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 3515,
                "End": 3831
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2466,
                "End": 2806
            },
            {
                "InterPro-ID": "IPR000873",
                "InterPro-Name": "AMP-dep_synth/lig_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 4531,
                "End": 4852
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 2958,
                "End": 3033
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 7462,
                "End": 7477
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1800,
                "End": 1904
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6297,
                "End": 6382
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1909,
                "End": 1979
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6929,
                "End": 7325
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 379
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4524,
                "End": 4895
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3508,
                "End": 3875
            },
            {
                "InterPro-ID": "IPR042099",
                "InterPro-Name": "ANL_N_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5550,
                "End": 5921
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 3978,
                "End": 4053
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 3637,
                "End": 3648
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 489,
                "End": 592
            },
            {
                "InterPro-ID": "IPR001031",
                "InterPro-Name": "Thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 7525,
                "End": 7759
            },
            {
                "InterPro-ID": "IPR020845",
                "InterPro-Name": "AMP-binding_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 137,
                "End": 148
            },
            {
                "InterPro-ID": "IPR020802",
                "InterPro-Name": "PKS_thioesterase",
                "InterPro-Type": "DOMAIN",
                "Beg": 7528,
                "End": 7771
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5001,
                "End": 5073
            },
            {
                "InterPro-ID": "IPR006162",
                "InterPro-Name": "Ppantetheine_attach_site",
                "InterPro-Type": "PTM",
                "Beg": 2988,
                "End": 3003
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 5002,
                "End": 5077
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2951,
                "End": 3033
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3970,
                "End": 4059
            },
            {
                "InterPro-ID": "IPR009081",
                "InterPro-Name": "PP-bd_ACP",
                "InterPro-Type": "DOMAIN",
                "Beg": 487,
                "End": 562
            },
            {
                "InterPro-ID": "IPR025110",
                "InterPro-Name": "AMP-bd_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 3890,
                "End": 3960
            },
            {
                "InterPro-ID": "IPR025110",
                "InterPro-Name": "AMP-bd_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 7340,
                "End": 7414
            },
            {
                "InterPro-ID": "IPR025110",
                "InterPro-Name": "AMP-bd_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 2864,
                "End": 2938
            },
            {
                "InterPro-ID": "IPR025110",
                "InterPro-Name": "AMP-bd_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 394,
                "End": 468
            },
            {
                "InterPro-ID": "IPR025110",
                "InterPro-Name": "AMP-bd_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 4910,
                "End": 4984
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1490,
                "End": 1670
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 1547,
                "End": 1645
            },
            {
                "InterPro-ID": "IPR013217",
                "InterPro-Name": "Methyltransf_12",
                "InterPro-Type": "DOMAIN",
                "Beg": 6042,
                "End": 6140
            },
            {
                "InterPro-ID": "IPR045851",
                "InterPro-Name": "AMP-bd_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2849,
                "End": 2950
            },
            {
                "InterPro-ID": "IPR036736",
                "InterPro-Name": "ACP-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2964,
                "End": 3061
            }
        ],
        "ipr_mapped": [
            35,
            70,
            45,
            46,
            29,
            30
        ],
        "response#1": "MSTTGERVKKIIAEHLSVNADKVVESASFIEDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFIDNAAKSAKPSPNATHTHTHPPLTHSHTHTHTHTHTHPHPTPLSQTSPTTTPSPSTENHHPSPPPSPRTPPPPCPLPSGSEQPPRHSYEEKTGHVRTMSTTGERVKKIIAEHLSVNADKVVESASFIEDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDATKFIDNAAKSA",
        "response#2": "MAFSAVRTVARTAVRSVARPEPGGGGCRVCGEEGGGEHDGNRRSVRTPRVQTYPSSSYPASPPTPPTTTTTTPTPPDPPPPHPPPPPHHHHHPPPPPTTTTTTTTTPTPPPSHPPPRPPTPPPPPPPTTTTTLTMSDTAERVKKIVVEHLGVDADKVTESASFIDDLGADSLDTVELVMAFEEEFGTEIPDDAAETILTVGDATKFLDKASA",
        "response#3": "MPGPNPPVPACPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPRVKRIVAEHLGVDADRVTDGASFVDDLGADSLDTVELVMAFEEEFGTEIPDDAAETIATVGDAVRGDGGGGGPGGGGGGGGGGGGGGGGGGGGGGGGGGGGRGGGGGGGGGGGGGGGGRGRRGAAAAADVTRRRPRPRRPRRRRRRRRRRRRLPPTATTDTAAAAAAAAACAAAAAAAAAADVTRRRGPRRRRPRRGRRRRPRRRRPRRRRPRRRRRRRRRRRRRRRRR"
    },
    {
        "reference": "MSASGKEKPLKDVPGSYGVPVVGALKDRLDFYWFQGEVEFYKSRMEKNQSTVFRVNFPPGPPGFPEGHGIVLLDQVSYSVLLDNAKVDKRDTLIGSYMPDLAFTGGYRTLPYLDTAEEKHTTYKSLMFEILHESAQRFGPELSSAFDRTAQEWEAKIAKDGSVESLSTAGNMVIQFLYKTITHQDPMATMGDDPHSVYMAWTGVQFAGIAYTNLPHITEELLMHSFQLPFFPIKKKYEQIVEFFRSAGSGLLDLAVTKYGLDREEALHNLVFSFGINTRLGLLKMFPPILFFIARAGAEFQARLKQEIRGRMKKREDAASIQALGDLKLVKATVLEVFRLMPSIFVAFGRARQDLEVESHDARYKIKKGELLGTHQYFVMRDPVVFKDPHSFVPDRFMGSEGAALLPHIVWSNGRETDSPTPTNKQCPGKNQAELIAVQFIAEMFLRYDSWEVTQESSVSATKLDVHLCKLVKRS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein must be able to perform the heme binding,lyase activity,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0016836",
                "GO-Name": " hydro-lyase activity "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            32,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 471
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 427,
                "End": 445
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 327,
                "End": 343
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 378
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 380,
                "End": 398
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 299,
                "End": 456
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 456
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 471
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 427,
                "End": 445
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 327,
                "End": 343
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 364,
                "End": 378
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 380,
                "End": 398
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 299,
                "End": 456
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 456
            }
        ],
        "ipr_mapped": [
            18,
            21,
            22
        ],
        "response#1": "MTPDHQIHVDVVRTKLTQAINRLTRDISDETSHVLTTEWTDSKEWHEVSLKDTILRIVARLSSRVFLGLDLCRNERWLKITTDYTVNAFKAVEELRKVPYFLRPVVHWFLPSCRQLRAQIAEAREIINPVLEERRRIKEEALKRGEEVPQYNDAIEWFDEVAKGSEYDPALAQLRLSVAAIHTTSDLLTQVLFDLCANPELIQPLREEVIRVISENGWKKTALYNLKLMDSVLKESQRLKPVSVVTMRRMAMKDVTLSDGTFIPKGTKVAVSAHPMWDPEQYPDPEKFDGYRFERLREQGNNAQFVSTSPDHLGFGHGRHACPGRFFASNEVKIALCHILLKYDIKFVDGVKPELVNSGNFFSADSSAKIMVRRRKEEISLS",
        "response#2": "HDVVRDHLTKAINRLTEDLSEETSHVLRTEWTDNPEWHEVNLKETILRLVAQLSSRVFIGLPLCRNENWLKITTDYTVTVFTAAVELRVFPEFLRPIVHWFLPSCRKLRAQIAEAREIINPVIEERKRIQRTTKEQVKPYNDIIEWFDEVAKGSEYDPAVAQLQLSVAAIHTTSDLLTQVMFNLCSNPELIQPLREEVIRVLKENGGWKKTALYNLKLMDSVLKESQRLKPLGLLSMRRMAGKDVKLSDGTFIPKGTMVNVSTHRMWNDPSIYPDPEKFDGYRFYKLRQVPGQENSAQLVSTSPDHLGFGHGKHACPGRFFAANEVKIALCHILLKYDFKFVDGEKPKMVNAGFVVHADPSARIMVKRRKEEIL",
        "response#3": "SQYDLAHSQLVLSFAAIHTTSDLLTQVMFDLCAHPELIQPLREEIIAVVGKDGWKKTALYNLKLMDSVLKESQRLNPPVMATMVRRVVKDGFKLSDGTFLPKGTKITIPAHAMGHDPEIYPDPEKFDGYRFVKLREQPSGDSEVPKNASQFVSTSPDHLGFGHGRHACPGRFFASNEVKIALCHILLKYDFRFEDGSRPKNMSHGFSLSADPTARIMVKRR"
    },
    {
        "reference": "MVLSRLDFPSDFIFGSGTSASQVEGAALEDGKTSTAFEGFLTRMSGNDLSKGVEGYYKYKEDVQLMVQTGLDAYRFSISWSRLIPGGKGPVNPKGLQYYNNFIDELIKNGIQPHVTLLHFDIPDTLMTAYNGLKGQEFVEDFTAFADVCFKEFGDRVLYWTTVNEANNFASLTLDEGNFMPSTEPYIRGHNIILAHASAVKLYREKYKKTQNGFIGLNLYASWYFPETDDEQDSIAAQRAIDFTIGWIMQPLIYGEYPETLKKQVGERLPTFTKEESTFVKNSFDFIGVNCYVGTAVKDDPDSCNSKNKTIITDMSAKLSPKGELGGAYMKGLLEYFKRDYGNPPIYIQENGYWTPRELGVNDASRIEYHTASLASMHDAMKNGANVKGYFQWSFLDLLEVFKYSYGLYHVDLEDPTRERRPKASANWYAEFLKGCATSNGNAKVETPL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds,hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            },
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008422",
                "GO-Name": "beta-glucosidase activity "
            },
            {
                "GO-ID": "GO:0016798",
                "GO-Name": " hydrolase activity, acting on glycosyl bonds "
            }
        ],
        "go_f_mapped": [
            184,
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 434
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 434
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 283,
                "End": 297
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 346,
                "End": 354
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 384,
                "End": 401
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 435
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 434
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "ALPAAPAPAPPAAPAAPSAPPPPPPPTPPPPPPAAPPAPPPPAPPPAPAPPPPPAPAPAPAGPPPPPPPAAPAPPAAPPPPPPPPPPPAPPPPAAPPPPPPPRPPPPPAPRPPPPWPPRARRRRRSGRGGTRGGRRGGRGRGSRRGGRARRRRGGRGGRGGRRRGRGRRRRRRVGRGGRRGRRRGGQRRGGRRRGGGGGGGRRRGRQRRGGGGGRRRGGRRRPRPPAPPRRRPRARRGGARARRRSRGAAARGRGGAAAGAAAGAAAAAAAGGGGAAAGGGGGGAAAAAGRRGGRRGGGGGGARGGGARGGGGRGARRRRGRGGRRRGRRGGAGGGGGAGGGAEAAAAAAGVERGGERAAAAAAAAAAAAAAAAAAAGPAPPAAAPPAAPAAGQA",
        "response#2": "FFDLRSHGRSPRSDVATFADYVADLHQVVEHYQLTDFHLVGHSMSAMIAAHFAAAYPEKVRSLTLLAATAKYVNEDYDGGFEQEDIDEIFGFMEENFAGWAEGFAPMVVADEEARALCAEMISSVPAASYLALSESLRDTDLRDVLAGVSVPTHVIAGTDDVISPPEVSRYIADHIAGPAEVHLLDGCGHLVHLEKPDEVAKLLSDFISRV",
        "response#3": "MKILHISDTHLGWEKPPEKTPEERAEYVEKRVEKIVEIAKKEKPDLVIHTGDLVHKRPTEKEYEPAKKFFELLAEAGIPLYVIPGNHDNPEKFQEIVKETKGEIKWIHGEPIELDDWVFVGIGYSPEKLEEALKEAKGKKKIVATHYPPKAKQTGVRADWEETKELAEKYDVDYIICGHAHEYFKEEKVKKTTVINPGPLTEKGWELEPSYTIIEVEPKKKKEEKKEEEKKEEKKKEKPKEEKKEKKEEKEEEKKEEKEEKKEEKKEEKKEEKKEEKPAEKKEEKKEEKPAEAKVRKVKCPKCGYEFEVKEPKLPICRIGPKGTKVKCPKCGYTFEV"
    },
    {
        "reference": "MAEASSFLAQKRYAVVTGANKGLGLEICGQLASQGVTVLLTSRDEKRGLEAIEELKKSGINSENLEYHQLDVTKPASFASLADFIKAKFGKLDILVNNAGISGVIVDYAALMEAIRRRGAEINYDGVMKQTYELAEECLQTNYYGVKRTINALLPLLQFSDSPRIVNVSSDVGLLKKIPGERIREALGDVEKLTEESVDGILDEFLRDFKEGKIAEKGWPTFKSAYSISKAALNSYTRVLARKYPSIIINCVCPGVVKTDINLKMGHLTVEEGAASPVRLALMPLGSPSGLFYTRNEVTPFE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Sc_DH/Rdtase_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            },
            {
                "GO-ID": "GO:0016616",
                "GO-Name": " oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor "
            }
        ],
        "go_f_mapped": [
            4,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 283
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 226,
                "End": 245
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 101
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 163,
                "End": 171
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 175
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 30
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 245,
                "End": 262
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 157,
                "End": 173
            },
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 213,
                "End": 241
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 215,
                "End": 265
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 283
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 226,
                "End": 245
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 101
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 163,
                "End": 171
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 175
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 30
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 245,
                "End": 262
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 157,
                "End": 173
            },
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 213,
                "End": 241
            },
            {
                "InterPro-ID": "IPR045313",
                "InterPro-Name": "CBR1-like",
                "InterPro-Type": "FAMILY",
                "Beg": 12,
                "End": 301
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 215,
                "End": 265
            }
        ],
        "ipr_mapped": [
            8,
            9,
            7
        ],
        "response#1": "MAHWATIRGPPPPPPPPLPQRGATPRDVVPEWPRARPAAARVRHAFSGTRHSARAMARLEGKVALITGAASGIGEATARLFHEHGARVVLVDIQEERGQALAQSLGDRAVFVRADVTQEADVERMVATAVERFGRLDCAFNNAGISAGFVDRPVAEVDLEEWQRVLAVNLTGVLLCMKHEIRAMLPAGGGSIINASSIAGLVGVHYMPAYTASKHGVVGLTKNAALYYGPRGIRCNAICPGGIDTPMLREYVAARTGRPLDEVRQQYLASHPLARMGRPEEVARAALFLASDESSFVNGVVLPVDGGYTAQ",
        "response#2": "MTSSSASTSLKDKVVLITGGTSGLGFATALAFSRAGAKVVIAGRREDRGQEAVNKLAAVSSPNCPKPLFVKCDVSKPDEVQAFVDAAVSAFGRLDVAINNAGIMRDASLSETTVEDYDKVISVNLRGVFLGTKFQVPHMLKNGGGGSIVNMSSIAGLTGFPGRSVYCASKAGVDGLTKALAVELAPHIRVNSVAPGYIDTPMISSLPKPLFVKCDVSKPDEVQAFVDAAVSAFGRLDVAINNAGIMRDASLSETTVEDYDKVISVNLRGVFLGTKFQVPHMLKNGGGSIVNMSSIAGLTGFPGRSVYCASKAGVDGLTKALAVELAPHIRVNSVAPGYIDTPMISSLPEKEKMAAAIPLGRQGKPEEVADVVLFLASDKSSYVTGEVIRVNGGF",
        "response#3": "MSSTFPRLKDKVAIVTGGASGIGEATAKLFAAAGAKVVIADIQDEAGRRVEEAIKAETGNSAVFVHTDVSKEDEVAKLVETAVSTFGRLDCAFNNAGIEQRAPAMDTTVEDWDKVIAVNLRGVTLCMKHEIKQMQKQGGGSIINTASIMGVVIGKKGSIINASSIHGLVGLPLRSGYTASKHGVVGLTKSVALDYAKDNIRCNAICPGKVETPMLQAYFDRAPDPQAARDQFTAATMLKRLAAPEEIARAALFLASDESSYVTGIVLPVDGGFTAVTSWSW"
    },
    {
        "reference": "MCNVSQDSCNIDSRLDSLFPPTLYIFVMVIGFPTNCLSLWAAFVQVRQKNELGVYLLNLSISDLLYIATLPPWVNYFLHQDNWIHGPESCKLFGFILYTNIYISIGFLSCISVDRYLAVAHPLKFAKVRRVKTAAVVSAVVWAIEIGANSAPLFHNELFEDRFNHTFCFEKYPMEDWVAQMNLYRVFVGFLFPWVLMLFCYQGILRAVKTNVSTEREEKAKIKRLALSLIAILLFCFAPYHLILLSRSVVYLGQPCDCTFEENIFTAYHVSLALTSLNCVADPILYCLANEGARSEVTRGLAPLMKFFSASRPNMDSFARSVTLDTPWSSRRAAAPSPRSWSLCGQTGGRGRRSRVRRRRDCKC",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            }
        ],
        "go_f_mapped": [
            0
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 286
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 286
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 43
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 73
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 182,
                "End": 205
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 97,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 133,
                "End": 154
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 268,
                "End": 294
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 222,
                "End": 246
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 103,
                "End": 119
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 286
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 286
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 183
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 124,
                "End": 136
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 246,
                "End": 261
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 22
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 320,
                "End": 338
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 148,
                "End": 166
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 208,
                "End": 220
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 43
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 73
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 182,
                "End": 205
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 97,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 133,
                "End": 154
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 268,
                "End": 294
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 222,
                "End": 246
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 103,
                "End": 119
            }
        ],
        "ipr_mapped": [
            0,
            1
        ],
        "response#1": "MSFLDLCYSSVITPKMLVNFLSEKKTISYAGCATQLYFFLAFGSTECFLLAVMAYDRYVAICNPLLYTVKMSPRVCILLVAGSWVGGSVNSLIHTLLTFRLSFCGNRINHFFCDIPPLLKLSCSDTHVNELVVFAVCGFVIMSTFLFISVSYVFIVSTILKIRSTEGRHKAFSTCASHLTAVSIFYGTILFMYLQPKSSYSTDQNKVVSVFYTVVTPMLNPFIYSLRNKDMKGALKRLLGRK",
        "response#2": "MTNPTNHTNHTNHTNHTNHTNHSHTSHPLFYTIVYTLVFIVGLTGNTLTLYVFLRSSKMKKNVSTIYMINLSVSDLLFTLTLPFRVYYYVHPDWPLPGWLCPFTGFVFYVNMYASVIFLTCISVDRYLAIVHPLRYTRLRTPRLAWRVSAGVWVLVVSITLPVAVQTKINTDAGGKKVCFETWTGKQAVWYTGAVTFLFFLLPLLIISVCYSLICRSLSRSLRKVSGSDSSDSDSKRKAVRMVLVVVTVFIVCFTPFHVMLIMHYVTRHQKPLYAVYHFTVALSSLNSCLDPIIYYFVSDNFRREVARVLRRSSRSSSSTGSSFFTGSSSFTGSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSRSSRSSSSSSSSSSSSSSSS",
        "response#3": "YFFLSNLSFIDLCYSSVTTPNMLVNFLAEKKTISFLGCATQMYFFLSLGTTECFLLAVMAYDRYVAICNPLHYTVIMSPRVCLLLVMGSWVGGSLNSLLHTLLTFRLSFCGSNVINHFFCDIPPLLKLSCSDTHVNELMIFFSSGLIVLGSFVFIVISYVYILSTILKIHSTEGKRKAFSTCASHLMVVTLFYGTIIFMYVKPKSSYSTDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRVLRKKLLSGSTSS"
    },
    {
        "reference": "MEYLPYIATSIACIVILRWALNMMQWLWFEPRRLEKLLRKQGLQGNSYKFLFGDMKESSMLRNEALAKPMPMPFDNDYFPRINPFVDQLLNKYGMNCFLWMGPVPAIQIGEPELVREAFNRMHEFQKPKTNPLSALLATGLVSYEGDKWAKHRRLINPSFHVEKLKLMIPAFRESIVEVVNQWEKKVPENGSAEIDVWPSLTSLTGDVISRAAFGSVYGDGRRIFELLAVQKELVLSLLKFSYIPGYTYLPTEGNKKMKAVNNEIQRLLENVIQNRKKAMEAGEAAKDDLLGLLMDSNYKESMLEGGGKNKKLIMSFQDLIDECKLFFLAGHETTAVLLVWTLILLCKHQDWQTKAREEVLATFGMSEPTDYDALNRLKIVTMILNEVLRLYPPVVSTNRKLFKGETKLGNLVIPPGVGISLLTIQANRDPKVWGEDASEFRPDRFAEGLVKATKGNVAFFPFGWGPRICIGQNFALTESKMAVAMILQRFTFDLSPSYTHAPSGLITLNPQYGAPLMFRRR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 79,
                "End": 522
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 460,
                "End": 470
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 339,
                "End": 365
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 424,
                "End": 448
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 470,
                "End": 493
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 319,
                "End": 336
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 330,
                "End": 347
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 461,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 383,
                "End": 394
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 470,
                "End": 481
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 463,
                "End": 472
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 85,
                "End": 497
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 522
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 79,
                "End": 522
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 460,
                "End": 470
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 339,
                "End": 365
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 424,
                "End": 448
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 470,
                "End": 493
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 90,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 319,
                "End": 336
            },
            {
                "InterPro-ID": "IPR050665",
                "InterPro-Name": "Cytochrome_P450_Monooxygen",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 515
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 330,
                "End": 347
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 461,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 383,
                "End": 394
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 470,
                "End": 481
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 463,
                "End": 472
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 85,
                "End": 497
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 522
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MIRERRKTRTEKPNDMIQWMMDAAETPEEKTDDLIVHRVIVLAFAAIHTSSMTMTHAVFDLAARPEYIQPLREEQIAVHKECNGEWDKTALYKMKLMDSFLKESQRMNPIGLVAMRRLAKEDFTFSDGTRIPKGTRFSVPCYAMGRDPAIYPDPEKFDGYRFYERRHQLVSTSPEHLTFGHGKHACPGRFFAANEVKIALSHILLNYDIKLVDGERPKNVNYGNVILSDPSARVMLRKR",
        "response#2": "MALFTEFSTTQLLTLTSVFLLFLFLFSTIKKSNHHKSNLPPGPPKLPIIGNLHQLGSQPHRSLANLAKVYGPIMHLQLGEVSTVVVSSPEMAKEVLKNHDVVFANRPEIDALRVFSYNAMDIAWVPYGDYWRQMRKICTIELFSNKRIEATRHIREEKVSELVKYISQNVGKPIDVGKAAFTTALNLLSNIIFSKDLADYNSETSREFKEVIWVIMEEAGTPNISDYFPILKPLDLQGLRRRIKNNLDRAFGIFEGFIDERIEAKNKGET",
        "response#3": "MFFFLFFIVYNRFTTKKSKNLPPGPWKLPIIGNLHQLAGALPHRSLRDLANKYGPIMHLKLGEVSTIVVSSPEMAKEVLKTHDLVFANRPKLKSVDIFSYNAIDISFTPYGDYWRQTRKICTLELLSAKRIQSFRSIREEAVTKMVDDAKENPESLTMDRIKAAILDMFAAGTDTSSSTIEWAMTELIRNPRVMEKAQAEVRNVVAKRKDGFLVEESDILELVYLQMVVKETLRLHPPAPLLPRETTQDCKVSGYDIPKGTKVLVNAWAIGRDSYWENPLEFKPERFENSVDVKGRNFELIPFGAGRRICPGMPLGLATVELALAQLLFHFDWKLPTGMKPEDIDMDEKFGLTVHKAIPLHVIPVPLISMSQN"
    },
    {
        "reference": "MDGSHCKVIAPLLTERHQRMVTKDGHSTLQMDGAQTGLAYLRDAWGILMDMRWRWMMLVFSASFVIHWLVFAVLWYILAEMNGDLGLDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHIDGKPNLIFQVANTRPSPLTNVRVSAVLYQERENGKLYQTSVDFHLDGISSEECPFFIFPLTYYHSIIPSSPLATLLQHENPPHFELVVFLSAMQEGTGETCQRRTSYLPSEIMLHHCFASLLARGSKGEYQIKMENFDKTTPEFQTPLVSKSPNRTDLDIHINGQSIDNFQISETGLTE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Ig_E-set sharing conserved structural features; 2. The protein must be able to perform the potassium ion transmembrane transporter activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0015079",
                "GO-Name": "potassium ion transmembrane transporter activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005242",
                "GO-Name": "inward rectifier potassium channel activity "
            }
        ],
        "go_f_mapped": [
            200
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR014756",
                "InterPro-Name": "Ig_E-set",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 145,
                "End": 334
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014756",
                "InterPro-Name": "Ig_E-set",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 145,
                "End": 334
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 333
            },
            {
                "InterPro-ID": "IPR008062",
                "InterPro-Name": "KCNJ13",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 20
            },
            {
                "InterPro-ID": "IPR008062",
                "InterPro-Name": "KCNJ13",
                "InterPro-Type": "FAMILY",
                "Beg": 344,
                "End": 360
            },
            {
                "InterPro-ID": "IPR008062",
                "InterPro-Name": "KCNJ13",
                "InterPro-Type": "FAMILY",
                "Beg": 171,
                "End": 188
            },
            {
                "InterPro-ID": "IPR008062",
                "InterPro-Name": "KCNJ13",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 37
            },
            {
                "InterPro-ID": "IPR013518",
                "InterPro-Name": "K_chnl_inward-rec_Kir_cyto",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 331
            },
            {
                "InterPro-ID": "IPR041647",
                "InterPro-Name": "IRK_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 170,
                "End": 331
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 53,
                "End": 79
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 235,
                "End": 253
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 265,
                "End": 285
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 303
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 311,
                "End": 325
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 109,
                "End": 131
            },
            {
                "InterPro-ID": "IPR040445",
                "InterPro-Name": "Kir_TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 21,
                "End": 163
            },
            {
                "InterPro-ID": "IPR016449",
                "InterPro-Name": "K_chnl_inward-rec_Kir",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 359
            }
        ],
        "ipr_mapped": [
            476
        ],
        "response#1": "MTPSSSSSSSSSSSSSSSSSSSSSSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNKEMEEEEEEEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDDDDDDDDDDDDDDDDDDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEECSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSSSKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK",
        "response#2": "MLQYFRISPPPPPPPPPPPPPPPPPPPPPPPPPRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRPPPPPPPPPPPPPPPPPVLKEEEEEEEEEEEEEEEEESSSSSSSSSSSSSSSDDDDEEEEEEEEEEEEEAEEEEEEEEEEEEEEEEEEEEEEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQQ",
        "response#3": "MNKNKKNIISDDSSSSSSSSSSSSSSSSSSSSSSSSSSSKKNKKKNKKNKKNKKKSSSSSSSSSSSSSSSSSSSSSSSSSEEDEDEDEDSSSSSSEDDEDDDDEDEDEDDDDEDDDDEDEDEDDDDEDDDENDDDEDDDSSSSSSSSSSSSSSSEEEDEEEDEDEEEEGDEDEEDEDEEEEEDEDEDDEDEDDDEDDDEDEDKDEEEEDEDEEEEDEDDEDDEEEDEEKKNKKKKNDDDEDDEEDDDEEEEEDDEEEEDDDDEEEEDEEEEEKKKKKMKKMKKKKMKKKKKKNKKKKKKKKKMMKKKKKKKMKKKKNKNKKKNKNKKKKNKKKKNKNKKKRK"
    },
    {
        "reference": "MSSVLPTPVLPTPGKNINRGHFPDDFIFGAGTSSYQIEGAAREGGRGPSIWDTFTHTHPELIQDGSNGDTAVNSYNLYKEDIKIVKLMGLDAYRFSISWPRILPGGSINAGINQEGIKYYNNLIDELLANDIVPYVTLFHWDVPQALQDQYDGFLSDKIVDDFRDFAELCFWEFGDRVKNWITINEPQSYSDFFGVAYDTPPKAHALKASRLLVPTTVARPSKPARVFASTADPGTTTADQVYKVGHNLLLAHAAALKVYRDNFQDTQEGTFGMALVTQWMKPLNENNPADVEAASRAFDFKFGWFMQPLITGEYPKSMRQSLGPRLREFTRDQKKLLIGSYDYVGVNYYTATYVSSARPPNDNKAIFHTDGNFYTTDCKDGVLIGPLAGPAWLNIVPEGIYRCLQEIKAKYNNPVIYITENGVYEVNDTTKTLSEARVDTTRVDYLQDHLSYVLKARQQGVRVQGYFVWSLMDNWELRAGYTSRFGLIHVDYYNNFARYPKDSAIWFRNAFHKRLRIHVNKRPQEDDGAFDTPRKRLKK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008422",
                "GO-Name": "beta-glucosidase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 510
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 195
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 232,
                "End": 513
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 510
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 440,
                "End": 451
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 461,
                "End": 478
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 341,
                "End": 355
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 485,
                "End": 497
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 417,
                "End": 425
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 514
            },
            {
                "InterPro-ID": "IPR033132",
                "InterPro-Name": "Glyco_hydro_1_N_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 26,
                "End": 40
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "QQQQEQRRREEEQQERRRQQEEREREQQRREEERERRQEQRRAREQQEQQRAREQQEQQRAREQQRRAAAQQQQQQQQQQQQQQQQEAAAAAREREEAARRRAAEEAEAAAAEEAEAEAEAEAEAEEAEAEAAAGRERERAAAERAARARQEAAERAARARQREAARRAEERAREREMEEAARRARPEAAARERARAERRQARERQARQLSSMRPASTGAGGGGGGG",
        "response#2": "MKKEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEENNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEEEEEEEEEEEEEEEEEEEEEEEEEENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLHSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK",
        "response#3": "ERQRRKQEEERQQRQQQQQQQRQQQEAAARKRQEERRKREQDEEEKRKKEEARQKRQEQEEQRRRQQEQDAAAKRKKEEARQKRKEEEEQRQQQEQQQQEQEQQQEQQQQERQKQEEERRKQEQKRKKREEQEKAKAAAAKAEQERKAKAEAEANRKAKAAAAEEQKRQKEAAAKKEADAAAAAKKAAAKKKAQDEADAAAAKKKAAEAEGKGGRRRGRRR"
    },
    {
        "reference": "MSTYGTLLKVTSYGESHGKAIGCVIDGFLSNIEINFDLIQKQLDRRRPNQSKLTSNRNEKDKLVILSGFDENKTLGTPITFLIYNEDIKKEDYNSFINIPRPGHGDYTYFMKYHVKNKSGSSRFSGRETATRVAAGACIEQWLYKSYNCSIVSYVHSVGNIKIPEQVSKELENKNPPSRDLVDSYGTVRYNEKEKIFMDCFNRIYDMNASMLKTDEYNKNTLTIPSIDNTYINVKTNECNINQVDNNHNNYINDKDNTFNNSEKSDEWIYLQTRCPHPYTAVQICSYILKLKNKGDSVGGIATCIIQNPPIGIGEPIFDKLEAELAKMILSIPAVKGIEFGSGFNGTYMFGSMHNDIFIPVENMSTKKESDLLYDDKGECKNMSYHSTIQNNEDQILNSTKGFMPPKNDKNFNNIDDYNVTFNNNEEKLLITKTNNCGGILAGISTGNNIVFRSAIKPVSSIQIEKETSDFYGNMCNLKVQGRHDSCILPRLPPIIEASSSMVIGDLILRQISKYGDKKLPTLFRNM",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Chorismate_synth, Chorismate_synth, Chorismate_synth, Chorismate_synth, Chorismate_synth that shares evolutionary origin and functional similarity; 2. The protein should be classified within Chorismate_synth_AroC_sf, Chorismate_synth_AroC_sf, Chorismate_synth_AroC_sf, Chorismate_synth_AroC_sf, Chorismate_synth_AroC_sf sharing conserved structural features; 3. The protein must be able to perform the chorismate synthase activity,FMN binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004107",
                "GO-Name": "chorismate synthase activity"
            },
            {
                "GO-ID": "GO:0010181",
                "GO-Name": "FMN binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004107",
                "GO-Name": "chorismate synthase activity "
            },
            {
                "GO-ID": "GO:0010181",
                "GO-Name": " FMN binding "
            }
        ],
        "go_f_mapped": [
            58,
            59
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 526
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 360
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 424,
                "End": 509
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 507
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 230,
                "End": 520
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 172
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 516
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 226,
                "End": 374
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 412,
                "End": 523
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 196
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 526
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 360
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 424,
                "End": 509
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 507
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 230,
                "End": 520
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 172
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 516
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 226,
                "End": 374
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 412,
                "End": 523
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 196
            }
        ],
        "ipr_mapped": [
            142,
            143
        ],
        "response#1": "MFRVLTAGESHGPALVAVVDGCPPGLALTEADLQPDLDRRRPGTSRYTTQRREPDQVKILSGVFEGKTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGIRDYRGGGRSSARETAMRVAAGAIAKKVLAQQGIAVRAHVTQIPGIEIPFLERVDEIRKAGDSIGAVVEVTAENVPAGLGEPVFDRLDADIAHALMSLNAVKGVEIGDGFAVAELRGSENRDEMRIADGKPLFLSNHAGGILGGISTGQPVVARFAVKPTSSILVPGRTINRAGEEVEMVTKGRHDPCVGIRAVPIAEAMLALVLADHLLRQRGQCGL",
        "response#2": "MRYLTAGESHGPQLTAIIEGVPAGLTLTAEDINRDLQRRQGGYGRGRRMQIETDQVQITSGVRHGKTTGAPITLVVENKDHQKWLDIMSADEIEERLKSKRKITRPRPGHADLVGGMKYGHRDLRNVLERSSARETTMRVAVGAVAKKFLAEVGIEILNHVVEIGGVKAKEEAMSVAELKERADASPVRCLDEEAAKKMMEVIDAAKKEGDSIGGIVETVVGGVPAGLGSYVQWDRKLDAKLAQAVVSINAFKGAEFGVGFEAGRKPGSQVMDEILWSQEEGYTRRTNNAGGFEGGMTTGQPIVVRGVMKPIPTLYKALMSVDIETHEPFKASVERSDSCAVPAAGMVMESVVAWELATAFLEKFGGDSMEELKRNVAAHREYAKEY",
        "response#3": "RRRRRRRRRGRDRRRGRRRRRARGRRRRPRRRRAVSWAEIEANPFFCPDAAVVPLWEQYLDSLRKAGDSVGAVIEAVARGVPVGWGEPVYDRLDADLAKAMMSINAVKGVEIGDGFAAVELRGSENADEMRPGPDGRIGFLTNHAGGIEGGISTGQEIVVRVAVKPTSSIARPRVSIREGEATEVVTKGRHDPCVGIRATPIAEAMMALVLMDHALRHRAQCGDVASVTPRIAAAPPAR"
    },
    {
        "reference": "MSSVLPTPVLPTPGRNINRGHFPDDFIFGAGTSSYQIEGAAREGGRGPSIWDTFTHTHPELIQDGSNGDTAINSYNLYKEDIKIVKLMGLDAYRFSISWPRILPGGSINAGINQEGIKYYNNLIDELLANDIVPYVTLFHWDVPQALQDQYDGFLSDKIVDDFRDFAELCFWEFGDRVKNWITINEPESYSNFFGVAYDTPPKAHALKASRLLVPTTVARPSKPVRVFASTADPGTTTADQVYKVGHNLLLAHAAAIQVYRDKFQNTQEGTFGMALVTQWMKPLNENNPADVEAASRAFDFKFGWFMQPLITGEYPKSMRQLLGPRLREFTPDQKKLLIGSYDYVGVNYYTATYVSSAQPPHDKKKAVFHTDGNFYTTDSKDGVLIGPLAGPAWLNIVPEGIYHVLQDIKENYEDPVIYITENGVYEVNDTAKTLSEARVDTTRLHYLQDHLSKVLEARHQGVRVQGYLVWSLMDNWELRAGYTSRFGLIHIDYYNNFARYPKDSAIWFRNAFHKRLRIHVNKARPQEDDGAFDTPRKRLRKY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Glycoside_hydrolase_SF sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity, hydrolyzing O-glycosyl compounds required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004553",
                "GO-Name": "hydrolase activity, hydrolyzing O-glycosyl compounds"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008422",
                "GO-Name": "beta-glucosidase activity "
            }
        ],
        "go_f_mapped": [
            184
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 511
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 22,
                "End": 515
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 232,
                "End": 514
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 201
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 462,
                "End": 479
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 341,
                "End": 355
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 426
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 486,
                "End": 498
            },
            {
                "InterPro-ID": "IPR001360",
                "InterPro-Name": "Glyco_hydro_1",
                "InterPro-Type": "FAMILY",
                "Beg": 441,
                "End": 452
            },
            {
                "InterPro-ID": "IPR017853",
                "InterPro-Name": "Glycoside_hydrolase_SF",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 511
            },
            {
                "InterPro-ID": "IPR033132",
                "InterPro-Name": "Glyco_hydro_1_N_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 26,
                "End": 40
            }
        ],
        "ipr_mapped": [
            474
        ],
        "response#1": "MPPRRRRPPPPRPRRRPPPRPPPRPSPPPPPPPRPPPPRPPPPPPPPPPPRRPPPPPPRRRPPPAPPRRPPPARPPRRRPRRRPRPRPRPPRPRPRRPRRRRPRRRRRRPRRRRPPPPPRPRAGRRGRRAAAPRRRRRGRGRGRGGGGRRGGARGGGGGGAPRAGGGGVGTDVGRQAGGARACAAAVPDGVAAACGADGGAAAAAVAAVVAADDAPRRAARVERALAAYAAERRAARAGGGGGDGTAAAAAADVADPAAAADAYAARALALLGGGGGADAAAPPRAADAVAAAAAAVRPVTAEAVAGALATAPPATVAAVVEEVRACRRSGRGRQVKHVVGVGVGVVVVVVVGRAARAGSVERAAG",
        "response#2": "MKLKITWLGHASFKIEADGKVIITDPWFSPNPMCPKGVKPEDVKADVILLSHEHPDHLDKESVKKIKEKSKPKILAPESVEGAKVLKPNETLEIDGVKIHAVPATHHKVPAVGYVIETNGKKIYHAGDTRPFPEMEEIKEKYGEIDVALLPAGMLMTPEEAGKAVKILKPKIAIPMHYGEGMNADPEKFVEEVKKEGIEVRVLKPGETVEF",
        "response#3": "MKKKILLSFIPLTPILISSSYFIYNYNKKVININNNNKNNEIKELKDKLNELNNKLKELENELKNKEEEIKNLKNEENNKIKNKEEEIKNLKNELKEKKEEINNLIKEKEEEINNLIKEKENKENEIKNLENEIKELENKINELKNKDNKEEIEEKNNEIKKLEEEINNLKEENNKLNNEIKNLEEENNELKEEINKKEEEINKLNEKLNELKLKQEELENKLKEKENQINELNNKLKELENKLKEKENQINELNNKLKELENKLKELENKLKELENKKKEENNKLKE"
    },
    {
        "reference": "METVESSSSAELLRAQTHFSRQVFSFQNFAALKCALQLGIPDAIKQHGKPMNLSELTSALPINPSKAPCIHRLMRLLVNAGYFAQENECFALTSLGRLLLKDDPLHIRALVLSEFHTALVMPWFALSEWFKNDDVAPFATAHGKSFWDYTSCDPELRNVFDGAMACDSHLIAKALVTEFKYLFEGLKSLVDVGGGNGTLARSIAKAFTNLKCTVCDLPEAVANEQGDGNLDFVAGDMFDRVPSADAILLKSILHDWSDENCVKILKNCKRAISGKDKGGKVIVIDGVVELQKKAGNDDPGLDNMDMQMLVLFNSKERNEKEWAKLFSDAGFSDYGIVRTFGWWCIMELSP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 350
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 104,
                "End": 347
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 350
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 332
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 104,
                "End": 347
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 350
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 104
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 99
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 123,
                "End": 332
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 350
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 13,
                "End": 102
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MRRSSNRPAPRPPAAVDFADKSEGVPAEGTGGEDDPRMQRMVDAMAVRTKFFDDFFLDATAAGVRQAVILASGLDSRAYRLPWPAGTVVYEIDQPKVIEFKTATLAKLGAEPTAERRAVPVDLRDDWPAALRSAGFDPAQPTAWIAEGLLIYLPPEAQDLLFDRITALSAPGSRLATEAMPPGAFSEERARKYGLDFDMSALVYHGERNDAAAWLTAHGWEATATTMRELFARYGRPVPEDADEPPPGDLVSAVLR",
        "response#2": "MSAAAAPAPAAAAAAAAAPAPAQQQEPVQAASAIFPARANDDDDDDNDRASESSSIASSTASLSSSIMQYRFENGRTYHRYKEGKYLFPNDETEQDRLDLQHKIFTLTLGGRLGAPPINGRVLDVGTGTGIWAIDFADEHPEAQVIGTDLSPIQPSLVPPNCRFMVDDVEEPWTLSGPLWENNHFDYIHIRMLTGSIADWPRLYRQALDHLKPGGYFEQVEIDFAPRCDDDTLPPDCAFAKWSNLLIEASEKFGRTLTVVDDKTKKLLTDAGFVDVVETVFKWPLNPWAKDPHYKELGAWFQLNLTEAVEALSLAPLTRALGWTPSEIEVFLVDVRKEIKNRNIHAYWNIHVVYARKPFEN",
        "response#3": "MSRLSLYGNNTGEKRLAALLQRGSEQLGMTLSERQQQQLLLYLDLLVKWNKAYNLTAITDPDEMITRHLLDSLQVLPYLRQQSQGRLLDVGTGAGLPGIPLAIALPQRQFTLLDSLGKRTRFLQQVITELGLQNVSVVQARIEDYQPEQRFDTVTARALASLADLVGYCQPLLAENGRFLALKGQYPQAELDALPNDWQAEVVPLSVPGLDAERHLVVLTAKQSR"
    },
    {
        "reference": "METVESSSSAELLRAQTHFSTQLFSFQNYASLKCALHLGIPDAIKQHGKPMNLSELTSALPINPSKAPYIHRLMRMLVKAGYFAQENECFDLTPIGLLLLKDDPINIRALVLLELHPALLMPWIALSEWFQNDDATPFVTAHGKSFWDYTSRDPEFRKLFDEAMAGDSELISKVLVTEFKYVFEGLKSLVDVGGGNGTLARSIAKAFPNLKCTVFDLPEAVANEQGDGNLDFVAGDMFDRVPSADAILLKIILHDWSDENCVKILKNCKKSIPGKDKGGKVIIIEGVVELEKNAGNEYAGLENLDMEMMVLYNSKERTKKEWAKLFSDAGFSDYKFIPALDSWCIIELSP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 347
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 350
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 123,
                "End": 332
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 99
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 350
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 350
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 347
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 350
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 335
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 104
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 13,
                "End": 101
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MKVRELYNEIAEEYDKMREKPPKEVELILEELGDIKGKKILDAGCGTGRYTVKLALKGAEVVGVDISEEMLKKAREKLKEKKIKNVLFVKADIRNIPFKDESFDCVLCFRTLHHLPKEDQIKALKEFKRVLKKEGYLIISTRSKEELEFEEEEEWAKKWGLKWYYPTKEELKKMLEEVGFEIEKIKEIKEKEKYDSEKFKKRVEERLSKIIKKIGEEKFKEKLEELKKELEEKWKSENGEIYKESYWIIVKARKK",
        "response#2": "MAMIAAPIVEGEDDDSALGSDTASSTTSLSSSILQYRYENGRTYHSYKAGKYFLPNDETEQDRLDLQHHIFTLTLDGKLYLAPLDNPQRILDVGTGTGIWAIDVADKYPSAQVIGTDLSPIQPSLVPPNCRFEVDDVEEDWTLPPTNNLWQENNHFDLIHIRMLTGSIADWPRLYRQALDHLKPGGYFEQVEIDFAPRCDDDGTLPPDSALAKWCNLLVEASEKFGRTLRVAPLSKGLMTEAGFVDVVETVFKWPLNPWPKDPHLKELGRWFNLNLCEAIEALSMAPFTRALGWTPSEMQVFCADVRKDAKNRNIHAYNNIHVFYARKPLEAETSGAAE",
        "response#3": "MDSWDLASSVGATATMVAAARAVATRAPDALIDDPFAEPLVRAVGVDFFTRLASGELDLAELDEAGAARMQRIADGMAIRTRFFDDFFLDATAAGLRQAVILASGLDARAYRLDWPVGTVVYEIDQPKVIEFKTTTLADLGAAPTADRRTVPVDLRDDWPAALRKAGFDAAAPTAWSAEGLLIYLPPEAQDRLFDNITALSAPGSRLATEAMPGITDDEETKARMAKFDMSALVYHGERNDPAAWLAAHGWEVTATSRRDLFARYGRPVPDDMDDVFADVTFVSAVLR"
    },
    {
        "reference": "METVESSSSAELLRAQMHFSTQLFGFHYTAALKCAVKLGIPDAIKQHGKPMNLSELNSALSINPSKAPCIHRLMRILVTAGYFAQENECFSLTSAGRHFLKDDPLNIRALVLLELHPALVKPWIALGEWFQNDDVSPFATAHGKSFWDYVTSDPELRKLFDESMADDSQLIAKALVTEFRYVFEGLKSLVDVGGGSGTLARAIAKAFPNLKCTVCDLPDAVANEHGDGNLDFVAGDMFERVPSADSILLKHILHDWSDEKCVEILKKCREAIPKNGGKVIIVDKLLKNRGHGHAENEHDEATESPLSCDMEMLVLVNGKERDEKEWAKLFSGAGFNDYKYNITPVLGSTSLIEVNFYN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 104,
                "End": 342
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 355
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 99
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 104,
                "End": 342
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 357
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 355
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 104
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 356
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 15,
                "End": 338
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 123,
                "End": 336
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 13,
                "End": 102
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MSSTPQSSSSPRQSPPATAMAEPNNEQQENRPERPPYSPPNTDTGTGAVRMSRDPTVPGRRRYLPERRRPPPPPTAPVLEDNDSDSALGERASSITTSLASSIMQYRQENGRTYHRYKEGKYFLPNDETEQDRLDLQHHLFTLTLGGKLFLAPIGSGVQRILDVGTGTGIWAIDMGDKYPSAQVIGTDLSPIQPSLVPPNVRFEVDDVEEEWTWNPQFNQFDFIHVRMMTGSIADWPRLYRQVLDHLKPGGYFEQVEISFAPRCDDDTLSRENSALAKWYNLLIEASEKFGRPLTVDTAHTKKMLADVGFVDVVETVFKWPLNPWPKDPHYKELGRWFNLNLTEAIEALSLAPLTRALGWTPSELEVFLVDVRKEIKNRQIHAYWNIHVVYGRKP",
        "response#2": "MSAPAAVPAQPQPELVVNNDDSDDTDSALGASSVASSTTSLASSILQYRFENGRTYHRYKEGKYNFPNDETEQDRLDLQHHLFTLTLDGKLYLAPIGENVQRILDVGTGTGIWAIDMADKYPSAQVIGTDLSPIQPSFVPPNCRFEVDDVEEDWTFSRPFDFIHVRMMTGSIADWPRLYRQALQHLQPGGYFEQVEIDFIPRCDDDTLPPDCALAKWCSLLVEASDKFGRPLIVAPLSKKWMVDAGFVDVVEKVFKWPMNPWPADKHYKELGQWFNANLLEALSALSLRPFTALGWSTAEIQVLLADVRKEIKAYQAYSNIHVVYGRKP",
        "response#3": "MTSSVGATALMVAAARAVATRAPNALINDPFAEPFVRAVGVDLYELLPEDPEFDMQRITDGMAVRTKFFDDYFLDATAAGIRQAVILASGLDSRAYRLPWPAGTTVYEIDQPQVIEFKTTTLAGLGAEPTADRRTVAVDLRDDWPAALRAAGFDPAAPTAWIAEGLLIYLPPEAQDLLFDRITALSAPGSRLATEAMPDIFDDERMAEMAERWRSHGLDLDMASLVYHGERNDAAAWLAGHGWTATATTVRELLAANGRPIPETDDDAAFGDVRYVSATLT"
    },
    {
        "reference": "MASLRGSETMCNITTSCNVDSNIDQFFQPTLYIIVIVLGFPTNCMALWAAYMQVKQKNELGIYLMNLSIADLLYITTLPLWIDYFVHHDNWIHGQVSCKLFGFIFYTNIYVSIAFLCCISVDRYLAVAHPLKFAKVRRVKTALLVSAIVWLTEIVANSAPLFHDELFQDRFNHTFCFEKYPMEPWVAGMNLYRTFLGFLAPWGIMLAAYRGILRAVRGNVSTERQEKAKIKRLALSLILIVLLCFAPYHVLLLWRSVLFLINPCDCGGEENLFGAYHVTLALTSLNCVADPILYCFVNEGARHDVGRALATLLGLFQRGKSPETLMGASITVETPLAVKKPDFYSEVKTNAYKNDIEVLKDECLQMTILSVKK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            }
        ],
        "go_f_mapped": [
            0
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 230,
                "End": 254
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 141,
                "End": 162
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 190,
                "End": 213
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 27,
                "End": 51
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 276,
                "End": 302
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 60,
                "End": 81
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 105,
                "End": 127
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 43,
                "End": 294
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 111,
                "End": 127
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 294
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 230,
                "End": 254
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 141,
                "End": 162
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 190,
                "End": 213
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 27,
                "End": 51
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 276,
                "End": 302
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 60,
                "End": 81
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 105,
                "End": 127
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 43,
                "End": 294
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 111,
                "End": 127
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 30
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 182,
                "End": 191
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 216,
                "End": 228
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 156,
                "End": 174
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 328,
                "End": 346
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 132,
                "End": 144
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 254,
                "End": 269
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 42,
                "End": 294
            }
        ],
        "ipr_mapped": [
            0,
            1
        ],
        "response#1": "MAKGNHTAVTEFILLGLTDRPELQQILFGLFLSMYLVTVLGNLLIILATRVDSHLHTPMYFFLSNLSFVDICYSSVTVPKMLVNFQAERKTISYPGCATQLFFFLFLGDVECFLLAVMAYDRYVAICNPLLYTVKMSPQVCVLLVAGSWVAASLNALIHTLCTFRLSFCGSNEVNHFFCDIPPLLKLSCSDTHVNELVVFAVCGFIAMTTFLLILISYVYIISTILKIRSTEGRHKAFSTCASHLTVVSLFYGTIIFMYVRPKSYHTPDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRVLGRKLFSSEGSERIAEKGVRKKQEMP",
        "response#2": "SDSHLHTPMYFFLSNLSFLDICYSSVTVPKMLVNFLSERKTISYNGCMTQLYFFLALGTTECFLLAVMAYDRYVAICNPLLYTVKMSPQVCVLLVAGSWVGGSLNALLHTLFTMRLSFCGPNVINHFFCDILPLLKLSCSDTYVNELMILTDSGFVTMTCFLVILISYVYILSTILKISSEGRHKAFSTCASHLTVVSLFYGAIIFMYLRPSSSKMVSVMYTVVTPMLNPFIYSLRNKDMKGALKRLLGRKIFSSK",
        "response#3": "NPMYFFLSNLSFVDLCYSSTITPKMLVNFLVERKTISYPGCMTQLFFFLAFGTTECFLLAVMAYDRYVAICNPLLYTVKMSRQVCVLLAAGSYVGGSTHSLIHTLLTMRLTFCGPNEVNHFFCDIPPLLKLACTDTHVNELVMFLACGLITMTCFLLILISYVFIVSTILKIRSTEGKHKAFSTCASHLTVVTIFYGTIIFMYLRPKSSYTMDKMVSVFYTVVTPMLNPLIYSLRNKDVKGALKRLLGKKVFSHSS"
    },
    {
        "reference": "METVQSSSSAELLRAQTHFSTQLFSFQNYASLKCALHLGIPDAIKQHGKPMNLSELTSALPIKPSKAPYIHRLMRMLVKAGYFAQENECFDLTPIGLLLLKDDPINIRALVLLELHPALLLPWIALSEWFQNDDATPFVTAHGKSFWDYTSRDPEFRKLFDEAMAGDSELISKVLVTEFKYVFEGLKSLVDVGGGNGTLARSIAKAFPNLKCTVFDLPEAVANEQGDGNLDFVAGDMFDRVPSADAILLKIVLHDWSDENCVKILKNCRKSIPVKDKGGKVIIIEGVVELEKNAGNEYAGLENLDMEMLVLYNSKERTKKEWAKLFSDAGFSDYKFIPALDSWCIIELTP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 350
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 347
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 350
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 99
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 350
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 104
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 123,
                "End": 332
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 13,
                "End": 101
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 335
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 101,
                "End": 350
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 103,
                "End": 347
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MAATQPTVAQPKPPSPSPPPPSPSNPPQDTATLADDDDTDSAYEASSLASSTTSLASSILQYRFENGRTYHRYKEGKYFLPNDEREQDRLDMQHHIFTLTLDGKLYLAPLANPQRILDVGTGTGIWAIDMGDKFPSSAQIIGTDLSPIQPPSALVPRNVRFEVDDVEEEWTWNPQKNTFDLVHIRMLTGSIADWPRLYRQVLDHLKPGGYFEQVEIDFAPRSDDDSLDTARWCSLLIEASEKFGRTLRVCPKSKDWMVEAGFVDVVETVYKWPINPWPADPKLKELGAWFNLNLTEALEALSMAPLTRAHGWTQDEILVLLAGVRKELKDRRIHAYYHIYIL",
        "response#2": "MTAPQPPTAAPSSLPPKPDTLIVDDEPDDSAFDGRSIASSTTSLASSIMQYRFENGRTYHSKNGKYLLPNDETEQDRLDLQHKLFTLTLNNKLYLAPIDENSNVQRVLDVGTGTGIWAIDFGDEHPSAQVIGTDLSPIQPSAWVPPNVRFEVDDIEEPWTYPEAWKNSFDLVHVRMLTGSIADWPRLYRQILDSLKPGGYFEQVEIDFAIRCDDDSNALTRWHNLLIEASEKFGRPLRVAVQSKAWLTEAGFVDVVETVIKLPINPWPRDPNLKELGRYYVAPLQEDTRLREIGVWTNLALTEAIEALSMAPLTRALGWKPEEVTVLLAGVRKEINNRNIHAYWNIHFIHARKP",
        "response#3": "MSRNGQYVLPNDEREQDRLDLQHHIFTLTMDGKLYLAPIDTSSVQRILDVGTGTGIWAIDMGDKFPSAQVIGTDLSPIQPSLVPPNVRFEVDDVEDTEAWTWEKAYFDLIHIRMLTGSIADWPKLYRRVLDHLKPGGYFEQVEIDFAPRSDDDTLPPDCALAKWSNLLIEASDKFGRTLRVAPLSKGWMVDAGFVDVVETYYKWPINPWPKDPKLKELGRWYNLALTESLEALSMALFTRAHRWTPEE"
    },
    {
        "reference": "MLVSDRDKLEDKALIPLDNIFHNGKGTLVQASVTSVEKEKTGGFVVLDNGEKLPFYVLVVATGSKWSGPVDFPSKPEDVTKWISEQRKKFKDAKNIVIAGGGSVGLELSGEIKDIWPEKSVTIVHSQKKLLNSVYPDKFRDRAAQAYRPRTKLVLDDQIPGELTPGATSVTTRNGKTITADLIVPAWGNKPNTALLSSLKDVLSPNGCVKIRDTFQTQAYPDIFALGDIIDVNEQKQAGKAQAHAGMVAANVLSYVQGQPLKQKYKGSYELIVITNGKNDGVGYFGVWWGIVIGGWLASLLKAKDLMLPATRVATGASK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FAD/NAD-binding_dom that are essential for its biological function; 2. The protein should be classified within FAD/NAD-bd_sf sharing conserved structural features; 3. The protein must be able to perform the electron transfer activity,flavin adenine dinucleotide binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0009055",
                "GO-Name": "electron transfer activity"
            },
            {
                "GO-ID": "GO:0050660",
                "GO-Name": "flavin adenine dinucleotide binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004174",
                "GO-Name": "electron-transferring-flavoprotein dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0050660",
                "GO-Name": " flavin adenine dinucleotide binding "
            }
        ],
        "go_f_mapped": [
            71,
            77
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR023753",
                "InterPro-Name": "FAD/NAD-binding_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 244
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 84,
                "End": 258
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR023753",
                "InterPro-Name": "FAD/NAD-binding_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 28,
                "End": 244
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 84,
                "End": 258
            }
        ],
        "ipr_mapped": [
            402,
            43
        ],
        "response#1": "MRPVERAEVLVLGGGPAGLFAAFWAARLGARVRLLEALEALGGQLAAIYPEKPLYDVPGFPGLGAGELLERLRAQAEASGAEVRLGTRALALERLEGGGWRLEAEGPEGRVRHEAAAVLLATGAAPVPPPLPGLEALAPFAGRLLYALREPEALAGRRVVVAGGGEAAAETARRLARLGAEVTLVHRREAFRALPEVREALAEVEVRTLVELRALEGEGERLRAVVLADGTRLEADALLVALGWRPDPRLLEALGAACERTPRGLRVDAQGRTSLPGLYAAGDVLGEPALAVLAAAQGAAAALAALRHLRGEEPLLPPAPRAPAPTRAGA",
        "response#2": "MRTTTTTTNTTTTTNTTNTTNTTTTNTTNTTTTNTTNTTNNTTNTTNNTTNNTTNNNTTNNTTTNTTTNNTNNNTNNTTNNTTNNTTNNTTNNNTNNNTNNTTNKPTNNIIKEIEEIKEEKEKIKEKIKKEKEKTKKEIEKIKKKINEIKEKNKEINKELNEIKKESKEKIKEEIKEGKEKIKEEKEKIKEKINKLKEKIKEINKELNKQEKEIKEEINKIKNENKEEKEKIKEEKEEIKKEIEEIKKEIEKEIEETKKEKEKIKEEIKEIIK",
        "response#3": "MLIFFICISYININIILIKNKYKNIKNIIKNNIYNKRIILQKNNNKKIYKNNKNILYNKIIYKKIKIIKYKNKIYKRKKYKVIIYKYNKYNKYNNIKKYNNTIYNKIIYNKYNKYNKIKKYINNNIYKNKIYIYNKKYNNNNIYNYINKIYIFKKINKIYIYKYIYIYKNKNIIYNKYNKYYKNKNIFKYLYILYLYINNVIYNNKIKNIIYNNKFI"
    },
    {
        "reference": "MELITLLSALLVLAIVSLSTFFVLYYNTPTKDGKTLPPGRMGWPFIGESYDFFAAGWKGKPESFIFDRLKKFAKGNLNGQFRTSLFGNKSIVVAGAAANKLLFSNEKKLVTMWWPPSIDKAFPSTAQLSANEEALLMRKFFPSFLIRREALQRYIPIMDDCTRRHFATGAWGPSDKIEAFNVTQDYTFWVACRVFMSIDAQEDPETVDSLFRHFNVLKAGIYSMHIDLPWTNFHHAMKASHAIRSAVEQIAKKRRAELAEGKAFPTQDMLSYMLETPITSAEDSKDGKAKYLNDADIGTKILGLLVGGHDTSSTVIAFFFKFMAENPHVYEAIYKEQMEVAATKAPGELLNWDDLQKMKYSWCAICEVMRLTPPVQGAFRQAITDFTHNGYLIPKGWKIYWSTHSTHRNPEIFPQPEKFDPTRFEGNGPPAFSFVPFGGGPRMCPGKEYARLQVLTFVHHIVTKFKWEQILPNEKIIVSPMPYPEKNLPLRMIARSESATLA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen,heme binding,iron ion binding,monooxygenase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            },
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0102373",
                "GO-Name": "beta-amyrin 28-monooxygenase activity "
            },
            {
                "GO-ID": "GO:0020037",
                "GO-Name": " heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            }
        ],
        "go_f_mapped": [
            15,
            12,
            13,
            14
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 495
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 469
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 307,
                "End": 324
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 444
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 444,
                "End": 455
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 437,
                "End": 446
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 402,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 316,
                "End": 342
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 434,
                "End": 444
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 296,
                "End": 313
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 444,
                "End": 467
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 494
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 495
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 469
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 307,
                "End": 324
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 374
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 435,
                "End": 444
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 444,
                "End": 455
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 437,
                "End": 446
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 402,
                "End": 426
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 316,
                "End": 342
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 434,
                "End": 444
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 296,
                "End": 313
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 444,
                "End": 467
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 494
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MKEHMEIKGSGKDFVDVLLDLMNDEKFVLNNDNIKAVILDMFVAGTDTSSSTTEWAMSELIRNPRVMKKAQEEIDRVVGKNSLVEESDISNLPYLQAVVKETLRLHPPAPFLIRESTEDVEISGYNIPKGTKILVNAWAIGRDPSYWVDPLEFKPERFLESSIDVKGKHFELIPFGAGRRICPGLPLAYRTLHLALAQLLYYFDWKLPGGVKPEDIDMEEKFGMTVHKKTPLTVIPVKR",
        "response#2": "MRLVREHLESGKPFEPGKAAFLTALNLLSNIIFSRDLEDDSSESSEFKETVWEVMELVGIPNVSDYFPSLKYLDPLTGTRARLAKAFKKMDGIFQNIIDEHIAKKKLSQVKRKEEDLVDVLLELQEESPEHFNLDNIKAIIFDMFVAGTDTSSSTMEWAMTELIRHPRVMEKAQAEIRAVVGERRVEESDIGNLPYLQAVVKETMRLHPPAPLLLPREATEDVVLPSGELVKKGTKVMVNVWAIGRDKAIWGEDAEEFKPERFLESSSNSSVDFKGQHFELIPFGAGRRICPGIPLALRVVHLTLAQLLYHFDWKLPNGEEVDMSEDFGITAMKKVPLVAMPIPRV",
        "response#3": "MFIDLAGSPNVSDFIPILKFFDLQRTRKRLEIGFPKLMKIFDEVIDEHMKTKETGDVGKDLLDVLLELQKKDNLTRDDIKALILDMFIAGTDTTSSTMEWAMTELLKNPRVMEKAQAEVRSVVGDKNRVVEESDIPKLPYLQAVVKETMRLHPPAPLLIPREAREDVKLSGYDIPKGTKVFVNAWAIGRDPRYWKDPLEFKPERFLENSSVDVKGKDFELVPFGAGRRICPGMPMGLATVHLALAQLLYSFDWKLPNGEEVDMTETVGLTMRKATPLQAIPVPR"
    },
    {
        "reference": "MAGKSPEEQHPVKAYGWAATDSSGILSPFKFSRRATGDHDVRVKILYAGVCHSDLQSARNDMGCFTYPLVPGFETVGTATEVGSKVTKVKVGDKVAVGIMVGSCGKCDECVNDRECYCPEVITSYGRIDHDGTPTYGGFSSETVANEKFVFCFPEKLPMAAGAPLLNAGVSVYSAMRFYGLDKPGMHLGVVGLGGLGHLAVKFAKAFGVKVTVISTSTSKKGEAINDLGADAFLVSTDAEQMQAGSGTLDGILDTVPVVHPIEALLGLLKNHTKLVLVGATMGSFELPILPLGVGRKSVVSTIGGSTKETQEMLDFAAEHDITASVEIIPMDYVNTAMERIEKGDVRYRFVIDIGNTLTPPES",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016616",
                "GO-Name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 322
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 352
            },
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 195,
                "End": 318
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 154
            },
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 16,
                "End": 353
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 322
            },
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 357
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 11,
                "End": 200
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MGNTFSPPKPTWTVEDIPDLTGKVAIVTGGNTGLGKETVRALASHGAKVYLAARSEERGKAAIAELGSENVIFLQLDLSSLASVRKAAEEFLAKESRLDILINNAGVMATTTKDGFEIQFGTNHLGHFLFTNLLLPLLKKSAPSRVVNVSSSGHRLSPVRFSDYNFDAEAPPEDKGEPSLILAAKNWTEEGYDKWLAYGQSKTANVLFTYELARRLAGTGVTANSLHPGTILTDLQRHLPEDVRNNPEVTKTTKTVQQGAATTLYAALSKEVEGVTGKYFSDCNEASSSPHSYDVDAAKRLWELSEKLVGQEFGSDSFAT",
        "response#2": "MSSRLKGKVAIITGAASGIGEASALLFAREGASVVIADLLEDKGKAVADKITAAGGKAVFVKTDVSKEADVKSMVDTAVSTFGKLDVAFNNAGIATSTPMPKVPPSEFKFPAGSLPAHLATKSMSDMSEEDWDRVINVNLKGVWLCMKHEIPQMLKQGSGSIVNCSSVVGLVGNQGQANYAASKHGVVGLTKSAALEYGPQGIRVNAIAPGFIETPMTASASEEHRKAVVGLTPLGRAGKPEEIAYAALFLASDESSYVTGVVLPVDGGLTANAGFVQSMGAAGQALAESASSKL",
        "response#3": "MTDTHTAPATPAPPAPTAPAPAGGRLARRVAVVTGAASGIGRAVAALFAAEGARVVLADRDEEALRATAAALPGALAVRTDVTDPASVDALVAAALERYGRVDVCVNNAGIGGLTRRPTEDVPEEEWERVIAVNLTGTFRVARAVARVMRRQGRGRIINTASVSGLVGVHGQAAYAASKHGVVGLTRVLAVEWAPDGITVNAVAPGFTDTPMTARLFGAGPEPEPEPEPEPEPAPAAAPAAAAAPVGRPMSAYAVSKAGVAGLTRTVALEAGPHGIRANAVAPGYIDTPMTAALAAREPGAAEAQRAVSARVPLGRLGRPEEVAAAGLFLASDEASYVTGVVLPVDGGWTAAAP"
    },
    {
        "reference": "MTSHHSWYRYSINPFVLMGLVALFLAATANLTFFEKAMAVYPVSDNLGFIISMAVAVMGAMLLIVVLLSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTTMLQNAMQTDQAESKDLMNLAFFVRIIGLGVLPSVLVAVAKVNYPTWGKGLIQRAMTWGVSLVLLLVPIGLFSSQYASFFRVHKPVRFYINPITPIYSVGKLASIEYKKATAPTDTIYHAKDAVQTTKPSERKPRLVVFVVGETARADHVQFNGYGRETFPQLAKVDGLANFSQVTSCGTSTAYSVPCMFSYLGQDDYDVDTAKYQENVLDTLDRLGVGILWRDNNSDSKGVMDKLPATQYFDYKSATNNTICNTNPYNECRDVGMLVGLDDYVSANNGKDMLIMLHQMGNHGPAYFKRYDEQFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAKSIDWLKTHEANYDVAMLYVSDHGESLGENGVYLHGMPNAFAPKEQRAVPAFFWSNNTTFKPTASDTVLTHDAITPTLLKLFDVTAGKVKDRAAFIQ",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Alkaline_phosphatase_core_sf, Alkaline_phosphatase_core_sf sharing conserved structural features; 2. The protein must be able to perform the cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0046872",
                "GO-Name": "metal ion binding "
            },
            {
                "GO-ID": "GO:0016776",
                "GO-Name": " phosphotransferase activity, phosphate group as acceptor "
            }
        ],
        "go_f_mapped": [
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 234,
                "End": 527
            },
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 215,
                "End": 538
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000917",
                "InterPro-Name": "Sulfatase_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 237,
                "End": 525
            },
            {
                "InterPro-ID": "IPR012549",
                "InterPro-Name": "EptA-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 58,
                "End": 205
            },
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 234,
                "End": 527
            },
            {
                "InterPro-ID": "IPR040423",
                "InterPro-Name": "PEA_transferase",
                "InterPro-Type": "FAMILY",
                "Beg": 16,
                "End": 531
            },
            {
                "InterPro-ID": "IPR017850",
                "InterPro-Name": "Alkaline_phosphatase_core_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 215,
                "End": 538
            }
        ],
        "ipr_mapped": [
            512
        ],
        "response#1": "KEAKEKAEKEAKEAKEKAEKEAKEAKEKAEKEAKEAKEKAEKEAKEKAEKEAKEKAEEEAKKAEEEAKKAEEEAKKAEEEAKKAEEEAKKAEEEAKEAKEKAEKEAKEAKEKAEKEAKDSTDSTDTDSTDTDSTDTDSTDTDSTDTDSTDTDSTDTDSTDTDSTDSTDSTDSTDSTDSTDSTDTDSTDTDSTDTDSTDAKSTDAKSTDAKSTDAKSTDSTDAKSTDAKSTDAKSTDAKSTDAKSTDAKSTDAKST",
        "response#2": "MTDRETDREPDRESVRESDRESDRTDAAGSEGDSTADAVGGRVVDAAKDAVADAVADRVRRTAERVVGLERDRTPDRTADGPPDAAGEAVTDAVGEAADAAVTDDAGDAVGEAVDAGEAVAEAVAEAVAEAVTDAVGEAADAVADRVDEVAPEAAVTDAADRPVTDAVEETVDDALDRTVEEAVEETVDETVADRAPEPDVAAEPAVAAETAATDRTVATDRTVATDRAAADRAATAGVTDRAADRVADRVTDRTVATTDRAVATDRTATDRATDRTTTDRTTRDRTTGDRTVDRTTGDRTA",
        "response#3": "MRTRTRTRTRATTARTATRTRTTRTRTTRRTAPARTAPARTAPARTRTARTARTAPARTARTRTAPARTARTRTARTATRTAPARTRTRTARTGTARTRTAPARTRARTGTARTRTAPARTRTRAPARTARTRTRTRAPARTRTARTRTAPARTRTRTARTRTARTRTARTRTARTAPARTAPARTAPARTAPARTAPARTAPARTAPARTRPPPATPRTPRPPPATPRTPRPPPARTRTPPARTPRTRTPRPTRTPRTRTRTRTRTTRTDPDPDPDPDPDPDPDPDPDPDPDPDPDPDPDPDPDPDPDPDADADADADADADADADADADADPDPDPDPDPDPDPHPHPDPHTH"
    },
    {
        "reference": "MDLLQILLAIAGLLAILLLQKQWRTKTSPGAKAGRKLPPEPAGAWPVIGHLHKLGGPNPIYRNLAEWSDKYGPVMTLKLGMQNAVVVSDREAIKECFTTNDKALADRPPSSIGLHLGFNYAAIGAAPYGPYWRDMRKLVLLEVLSSRRLEMLRNVRISEIGTSIKELYSNIIRSSGGSGPAKVVISHWIEQLTLNYILRTIAGRRFSDDSSKDAQYVKGVINDFMYFAGQFVVSDVIPIPLLRWLDPQGHLKGMKRVAKEVDTMCEAWIQEHVQRRMREKPGPGQEQDFIDVLLNNRDVMRKAQEEIDNHVGKERWVDETDLKHLVYLQAIVKEGLRLYPPGPLGAPHRAIEDCQVGGYFIPKGTQLLVNVWKLHRDPRVWSEPEKFMPERFLTRQAEVDVFGHHFELLPFGSGRRACPGITFAVQVMHLTVARLLQGFDMTTPSNLPVDMTEGPGVTMPKAHPVEVLMMPRLPSALYEP",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0016853",
                "GO-Name": " isomerase activity "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0050596",
                "GO-Name": " vinorine hydroxylase activity "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 296,
                "End": 473
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 295
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 68,
                "End": 87
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 408,
                "End": 418
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 113
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 329,
                "End": 347
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 441
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 312
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 370,
                "End": 394
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 330,
                "End": 341
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 429
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 295,
                "End": 308
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 409,
                "End": 418
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 39,
                "End": 297
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 293,
                "End": 461
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 38,
                "End": 472
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 411,
                "End": 420
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR050651",
                "InterPro-Name": "Plant_Cytochrome_P450_Monoox",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 478
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 296,
                "End": 473
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 25,
                "End": 295
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 68,
                "End": 87
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 408,
                "End": 418
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 92,
                "End": 113
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 329,
                "End": 347
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 441
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 312
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 370,
                "End": 394
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 330,
                "End": 341
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 418,
                "End": 429
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 295,
                "End": 308
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 409,
                "End": 418
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 39,
                "End": 297
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 293,
                "End": 461
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 38,
                "End": 472
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 411,
                "End": 420
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MDTSSSTMEWAMSELLRNPRVMKKAQAEIDSVVGENRLVEESDISNLTYLQMVVKETLRLHPPAPLLVPREAREDVEVSGYNIPKGTKVFVNAWAIGRDPNIWGEDALEFKPERFESTDIKGQNFELIPFGAGRRICPGLPLGIATIELALAQLLYHFDWKLPEGTKPEDINMEEDKSGLTLHKAVPLMVVPIKRISSTSLRTSSVR",
        "response#2": "MLIAGSDTTASTASAALYHLLAHPRALRRLRAELDAAFPASAAALPPHAALQRLPYLQAVIEETLRLSPPAPGRLPRVVPPGGARVAGRWVPGGTEVGVAPYAAGRDPAVFGAAHGGGGAGGACWGGDAEAFRPERWLAGGEFAHDRREASQPFSLGPRACLGKNLAYMEMRLVLAVLVRRFDVALAPGVSEADVRMGKGFVRVQLR",
        "response#3": "MAKTAFGKELTDESKEFRDAIWEIMELAGTPNVSDYFPILKSLDLQGIRKKLAVNFGKALGIFEKFIDERIEERKAGTGERKDLVDVLLELQDEHPEYLNNDNIKAIILDMFVAGTDTSSSTMEWAMSELIKNPRVMEKAQEEVRKVTATQKENGPGVIVEESDISKLPYLQAVIKETLRLHPPAPLLIPRESTEDVKVSGFDIPKGTKVLVNAWAIGRDPSCWEDPLSFKPERFLKLDVKGRNFELIPFGAGRRICPGLPLGLRTVHLALANLLYHFDWKLPGEEVDMSESHGLTRMKKPLMAIPVKR"
    },
    {
        "reference": "MSINKILSAADITKALGEFKGADSFDHKKFFHMIGLKKKNAKDVEAVFYILDKDKSGFIEEDELKSVLKCFAPEGRDLSEKETKDLLTAGDEDGDGKIGVSEFIQLVANS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            }
        ],
        "go_f_mapped": [
            31
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 107
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 107
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 74
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 52,
                "End": 64
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 91,
                "End": 103
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 78,
                "End": 110
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 71
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 82,
                "End": 110
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 44,
                "End": 107
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 107
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 39,
                "End": 74
            },
            {
                "InterPro-ID": "IPR008080",
                "InterPro-Name": "Parvalbumin",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 108
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 52,
                "End": 64
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 91,
                "End": 103
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 78,
                "End": 110
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 43,
                "End": 71
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 82,
                "End": 110
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MASGGGEEEDMKEAFSLYDKNGDNKISAEELSTVMKSLGEKCTVEDCKKMISEVDADGDGFVDFEEFKTMMKKKKGGGEEEDMKEAFSLYDKNGDNKISAEELSTVMKSLGEKCTVEDCKKMISEVDADGDGFVDFEEFKTMMKKKKGGDNKISAEELSTVMKSLGLGEKCTVEDCKKMISEVDADGDGFVDFEEFKTMMKQGGNLVKDVAKALYPSP",
        "response#2": "MAEEDEELKRVFDRFDANGDGKISLEELGETMKSLGENVTEQELKEMIEEVDKDGDGFIDFEEFKAMMKASSVGGEEEEDMKEAFSVFDDKDGDGFISFEEFKVMMKKNKPHKTFMAEEDEELKRVFDRFDANGDGKISLEELGETMKSLGENVTEQELKEMIEEVDKDGDGFIDFEEFKAMMKASSVGGEEEEDMKEAFDVFDDNGDGKISAEELQSVLNKLGLKEGKTVEDCKRMISKVDKDGDGFVDFKEFKDMMKASFF",
        "response#3": "MELRSRCLLLLLVCCVCCLAKPTEKKDAGHKDTGHKDTKHHDDPKHHDTKLHHDDDSQNFNYDHEAFLGADEAKTFDQLTPEESKERLGKIVSKIDKDQDGFVTWDEMKDWMKDQVIKDYDEIVEDGRITDDKDFNADDGFSWKEMYARDERRWKMADKDGDLIATKEEFTAFLHPEEYDYMKEFVVKETMEDIDKNQDLIADEEEFTAFLHPEEYDYMKEIVVLETLEDHDKNGDGFIDLEEYIGDMYSRDGNYDPELTVGRDAYDDQKESDEPDWVKTEREQFVEFRDKNKDGKMDKEETKDWILPSYDQAEAEAKHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF"
    },
    {
        "reference": "MSNFTPDACNVDSGLDSVLPPSLYALVFTLGLPANLLALWAAWLQVRKGRELGVYLLNLSLSDLLLICALPPWTDYYLRRDVWGYGPGACRLFGFVFYTNLYVGAAFLSCVSADRYLAVAHPLRFPGARPIRSAAAVSALIWMLELAANAPPLLGEAIHRDRYNHTFCYESYPLSGRGAALANVGRVLAGFLLPWGVMMLCYAGLLRALRGSASCEQRERRRVRRLALGLPCVALLCYGPYHALLLLRSLVFLVGGGSVDAGGGCALEERLFPAYHASLALATLNCLADPALYCLACPGARGEVAKVVGGVVAWAMGKERRAWGERGGNGRGCGEGEEVGMVELRGNGREFVV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more GPCR_Rhodpsn_7TM that are essential for its biological function; 2. The protein should belong to GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn, GPCR_Rhodpsn that shares evolutionary origin and functional similarity; 3. The protein must be able to perform the G protein-coupled receptor activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004930",
                "GO-Name": "G protein-coupled receptor activity "
            }
        ],
        "go_f_mapped": [
            0
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 103,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 293
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 275,
                "End": 301
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 43
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 133,
                "End": 154
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 73
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 223,
                "End": 247
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 97,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 183,
                "End": 206
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 293
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 103,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 35,
                "End": 293
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 275,
                "End": 301
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 43
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 133,
                "End": 154
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 52,
                "End": 73
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 223,
                "End": 247
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 97,
                "End": 119
            },
            {
                "InterPro-ID": "IPR000276",
                "InterPro-Name": "GPCR_Rhodpsn",
                "InterPro-Type": "FAMILY",
                "Beg": 183,
                "End": 206
            },
            {
                "InterPro-ID": "IPR017452",
                "InterPro-Name": "GPCR_Rhodpsn_7TM",
                "InterPro-Type": "DOMAIN",
                "Beg": 34,
                "End": 293
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 209,
                "End": 221
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 148,
                "End": 166
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 124,
                "End": 136
            },
            {
                "InterPro-ID": "IPR002276",
                "InterPro-Name": "GPR4_orph",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 22
            }
        ],
        "ipr_mapped": [
            0,
            1
        ],
        "response#1": "MAEGNHTAVTEFILLGLTDRPELQRVLFGLFLSMYLVTVLGNLLIILATRVDSRLHTPMYFFLSNLSFVDICYSSVITPKMLVNFQVERKTISYLGCATQMYFFLAFGDTECFLLAVMAYDRFVAICNPLLYTVKMNPQVCVLLVAGSWVGGSVHAIIHTGLTFHLTFCGSNEVNHFFCDIPPLLKLSCSDTHINELVLFIFCGSVLMTTFSIILISYVFIVSTILKIRSTEGRHKAFSTCASHLTAVTLFYGTITFMYLQPKSNYSMDQDKMVSVFYTVVTPMLNPLIYSLRNKDVKGALGRVLGRK",
        "response#2": "MPHRHRHVLPPPPPPPRRLLPLPPLRPPAPIPPRRQPPPAAPRRPPPPRHLRPPPPPGMAEGNHTAVTEFILLGLTDRPELQVLLFGLFLSMYLVTVLGNLLIILATSSDSRLHTPMYFFLSNLSFVDICYSSVTTPKMLVNFLAERKTISYAGCATQLFFFLALGGTECFLLAVMAYDRYVAICNPLRYTVIMSPRVCVLLVAGSWVGGSVNSLIHTLLTFRLSYCGSNEINHFFCDIPPLLKLSCSDTSVNELVLFVSCGFIMMVTLLVILSSYVFILSTILKIRSTEGRHKAFSTCASHLTAVTLFYGTIIFMYVLPKSNYTLDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRLLGRKVFSGDSRKSTRSGNRFFPL",
        "response#3": "TISFLGCATQMYFFLAFGCTECFLLAVMAYDRYVAICNPLLYTVKMSPQVCVLLVAGSWVGGSLNAMVHTCMTFRLSFCGPNEVNHFFCDIPPLLKLSCSDTTVNELMMLFVVGGSVMTVTFLVILISYVYIVSTILKIQSTEGRHKAFSTCASHLTVVTLFYGTIIFMYVRPTSSYSMDQDKVVSVFYTVVTPMLNPFIYSLRNKDVKGALKRLLGRKIFS"
    },
    {
        "reference": "MEMMQLSFASAVVYSLIFFVFLLVKQLLKPKSHKKLPPGPWTLPIIGNLHQILGALPHRIFKDLSDKYGPLMRIMMGERTTIIVSSATMAKVVLHTHGLAVANRPINSVAKVICYNNLGVTFAEYGEYLKQLRQLYMLELLSPKRVQSFSAVFEDELQTFVKSIKSEVGQPMIIYEKSVTYLYSTICRVMLGNVCNEREKLIKICKKVSFYSAAPIRIEDLFPSMKFIISRIFSTNSILKDLLKDLDDVLDIVIAERENSQYAQEEEDMLGILLKHKRSDGNNSKLKITNKDIKAIIFELLLAATLSVADVVEWAMVEILRHPKVLKQVHDEVRQAFKGQKTITGSDLGKLEYLHMCFKESTRLHPAAPLLFPREAREEFEIDGYTIPKGSWVLTNYWAVGRDPRIWPKPDEFDPERFRNSDIEFYGNHFELIPFGTGRRGCPGILFGITEALYLLAALFYHFDWKLAGGITPEEIDMTEVFGAGCILKNPLNLIPRLAEN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 435,
                "End": 444
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 312,
                "End": 338
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 432,
                "End": 442
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 396,
                "End": 420
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 373
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 465
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 65,
                "End": 84
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 496
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 497
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 480
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 435,
                "End": 444
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 312,
                "End": 338
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 432,
                "End": 442
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 396,
                "End": 420
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 373
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 465
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 65,
                "End": 84
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 496
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 29,
                "End": 497
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 37,
                "End": 480
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "ETNITLDNIKALIMDMFVAGTETSSSTLEWAMAELIRNPRVMKKAQAEIDSVVGKRRVEESDISNLLYLQMVVKETLRLHPPAPLLIPRETMEDVKISGYDIPKGTKVLVNVWAIGRDPKIWGEDANEFRPERFENIKGQNFELIPFGAGRRICPGMPLGLATVNLALAQLLYHFDWKLPEGMKPEDVNMDEKFGITLQKKVPLWAIPVSRLSNRN",
        "response#2": "MEKPNDAIQWMIDHATEYEKDPYRLAHRMLALSFAAIHTSSDLLTHTMFDLCARPELIQPLREEIISVIKEHGGWKKTALYNMKLMDSVLKESQRLKPPVVVSMQRMATKDVTLSDGTFIPKGTKVSAAAYAMGRDESIYKDALTFDGYRFYRMRESGQENTAQFVATSPEHLGFGHGRHACPGRFFAANEVKIALCHILLKYDFKLVEGAKPKNVYQGFSIMPDPSAKVLVKKR",
        "response#3": "MLELQKRNEINENNIKAIILDMFVAGTDTSSSTMEWAMTELIRNPRVMEKAQAEIRSVIGERKVEESDINNLPYLQAVVKETLRLHPPAPLLAPRESREDLKFSDGSTIKKGTKVIVNVWAMGRDPKIWGSEDALEFKPERFLESVKGHNFELIPFGAGRRICPGMPLALPTVNLALANLLYHFDWKLPEGKVDMEEKFGLTLDMKNPLMAIPIPR"
    },
    {
        "reference": "MEFSFSSPLLYILYFLLFFIVRQLLKPKSNRKLPPGPRTLPIIGNLHQLRGSLPHRTLKKLSDKHGPLMHLKMGERSAIIVSDARMAKIVLHNHGLAVADRSVNTVASIMTYNSLGVTFAQYGDYLTKLRQIYTLELLSPKKVRSFYNCFEDELDVFVKSIRSQVGQPMVLYEKVSTYLYATICRTIFGSVCKEREKMIKIVKRTSLLSGTPLRMEDLFPSMRVFCRFSKTLNQLRGLLQEMDGILEDIIVEREKTTEILKEAKDDEDMLSVLLRHKWYNPSGARFRITNADIKAIIFELILAATLSVADVVEWAMVEILRHPAILKKVYDEGRGICKEKKRVTGYDVEKMEYMRLCVKESTRVHPAAPLLVPRECREDFEVDGYTVPKGAWVLTNCWAIQMDPEIWPEPEKFDPERYIRNPMDFYGSNFELIPFGTGRRGCPGILYGVTNAELLLAAMFYHFDWEIADGKKPEDIDLTENFGAGCIMKYPLTLVPHLANE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 435,
                "End": 444
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 495
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 495
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 396,
                "End": 420
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 432,
                "End": 442
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 312,
                "End": 338
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 373
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 62,
                "End": 81
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 465
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 480
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 435,
                "End": 444
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 495
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 31,
                "End": 495
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 396,
                "End": 420
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 432,
                "End": 442
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 312,
                "End": 338
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 355,
                "End": 373
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 62,
                "End": 81
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 442,
                "End": 465
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 292,
                "End": 309
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 480
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MEQPYDDAIQWFEENAKGSEYDPAIAQLSLSLAAIHTTSDLLTQVMFDLCARPELIEPLREEIIRVIQEHGWKKTALYNLKLMDSVLKESQRLKPVAVVSMNRMATEDVTLSDGTFIPKGTKVSVPAFAMGWDEKIYPDPEKFDGYRFVRMREEQKAAPGKENAAQLVSTSPEHLGFGHGKHACPGRFFAANEAKIALCHILLKYDWKLVDGPKAINEGFFLMADPAAKILVR",
        "response#2": "MAIVFIEWMSSSSFTLSTLLYSIILSFIFYLFTSRNKNSSKSAKNLPPGPPKLPIIGNLHQLGALPHRSLQALAKKYGPIMHLQLGEVSTVVVSSAEMAKEVLKTHDHIFANRPTLDAAKILSYNYTDMAFSPYGDYWRQMRKICTLELLSTKRIQSFRSIREEEVSNLIKYISSNKGQPVNLSEKFLSLTSSIICRVAFGVKYEDEVRKKFQAEVKEAVTLVV",
        "response#3": "HVVRANLTKAISRLTDDLSEETSFALTKEWTDNKEWHEVNLKETILRLVAQLSSRVFVGLPLCRNEKWLKITRDYTVDAFVAAEELRLWPEFLRPIVHRFLPSCKKLRAQLAEAREIINPVLEERRRAKEKAISEGREVETYNDAIEWFEENAVGSEYDPALAQLSLAVAAIHTTSDLLTQTMFDLCAHPELIQPLREEIISVMREAGLSKDGGIKKTALYKLKLMDSVLKESQRIKPIIVMDRMATKDVTLSDGTLIPKGTKISVAAHAMWRDPENYDDPEKFDGYRFVRMREAGDKNAHLVSTSPEHLGFGHGKHACPGRFFAANEAKIALCHILLKYDWKLPEGAERPKNIWSGFFITADPTAKVLVRRREVEL"
    },
    {
        "reference": "MGSYHDEKNVMGGSDQGELCSLAMTIASGSVPAMVLKALIELDVLELIKRAGPGAQLSPAQIVAQLPTKNPDAGTMLDRMLRLLASYEILSCSTQTLPDGRVERLYGLAPVCQFFTNNEDGATLGAIVQLSQEKLVVESWYHLKDAVLDGGIPFKKAQGMTIYEYPKTDPRFNQVFNSGMSNYSTIIMRDLLERYKGFEGISTLVDIAGGTGASINMVVSKYPTIKGINFDLPHVIKDAPSYDGVEHVGGDMFESVTKADAMLIKWTLCDWSDEHCLKLLKNCYNALPDNGKVIVCDYVLPMAPETSNAAKTVFLLDAIMLANFVGGKGRTKQEFEALARKVGFEGFEVPCSSYDFSVMELFKKKNN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 116,
                "End": 363
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 126,
                "End": 360
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 115
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 24,
                "End": 363
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 140,
                "End": 345
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 345
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 116,
                "End": 363
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 18,
                "End": 117
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 364
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 119
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 126,
                "End": 360
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MARTRNDDPAALLARGAEALGLTLSAEQQARLLRYLDLLVKWNKAYNLTAIRDPTEMVTRHLLDSLSVLPHLPAQARLLDVGSGAGLPGIPLAIARPDLHLTLLDSLQKKVRFLQQVSRELELTNVDVHAVRAEDWAASQRGQYDVVTARALAALPKLLGYCAPLLADGGRFLALKGQYPADEIAAAEGLTLLEVVPLTVPGLDAERHLVIIGKPAA",
        "response#2": "MASARTDGDSWDLASSVGATATMVAAARAVATRDPKALINDPFAEPLVRAVGVDFFTRLASGELDLDELDDEGAARMQRIADGMAIRTKFFDDFFLDATGAGIRQAVILASGLDSRAYRLPWPAGTTVYEIDQPQVIEFKTATLSGLGASPTADRRAVAIDLRDDWPTALRAAGFDPARPTAWIAEGLLIYLPPEAQDRLLDNITALSAPGSRFATEAMPDITVFDEERARAMRERWRRHGLDLDMSELVYHGERNDVAAYLAERGWRSATSTVRELFAANGLPVPDDADDAVFGELVYVSAELAPPPAPPPAGQPAGRLARGGSAR",
        "response#3": "PNDEREQDRLDLLHHIFTLTLDGRLYLAPLENPQRILDVGTGTGIWAIDVGDEVPSSAQVIGTDLSPIQPPSALVPPNVRFEVDDVEEDWTWKPDHFDLVHIRMLTGSIQADWPRLYRQIFQHLKPGGYFEQVEIDFAPRSDDDTLPQDCALRKWSELLIEASDKFGRTLRVAPLSKKMLVDAGFVDVVETVYKWPLNPWPADPKYKELGRWYNLALTEGLEALSMAPLTRALGWTPSEIQVLLVDVRKYAKDRRIHAYYPM"
    },
    {
        "reference": "MAVSSCARAFPSFECRSDAEFSGGIPRHDIPNSGKASILSHGSSVHGLSSLIYRFPPNFVRQLSIKARRNCSNIGVAQVVAASWSNNNSSPDFTPVAKAVDAAAAAAAAIAPVDTTVVNEDVALVENETCNDQNVQFDSLPSMKYASFLNSDGSVAIHAGERLGRGIVTDAITTPVVNTSAYFFNKTSELIDFKEKRRASFEYGRYGNPTTVVLEEKISALEGAESTLLMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFIETILPKMGITATVIDPADVGALELALNQKKVNLFFTESPTNPFLRCVDIELVSKLCHEKGALVCIDGTFATPLNQKALALGADLVLHSATKFLGGHNDVLAGCISGPLKLVSEIRNLHHILGGALNPNAAYLIIRGMKTLHLRVQQQNSTALRMAEILEAHPKVRHVYYPGLQSHPEHHIAKKQMTGFGGVVSFEVDGDLLTTAKFVDALKIPYIAPSFGGCESIVDQPAIMSYWDLSQSDRAKYGIMDNLVRFSFGVEDFDDLKADILQALDSI",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_major, PyrdxlP-dep_Trfase_small sharing conserved structural features; 2. The protein must be able to perform the transferase activity, transferring alkyl or aryl (other than methyl) groups,pyridoxal phosphate binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016765",
                "GO-Name": "transferase activity, transferring alkyl or aryl (other than methyl) groups"
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003962",
                "GO-Name": "cystathionine gamma-synthase activity "
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": " pyridoxal phosphate binding "
            }
        ],
        "go_f_mapped": [
            29,
            33
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 175,
                "End": 539
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 144,
                "End": 402
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 406,
                "End": 537
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 175,
                "End": 539
            },
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 155,
                "End": 537
            },
            {
                "InterPro-ID": "IPR054542",
                "InterPro-Name": "Cys_met_metab_PP",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 348,
                "End": 362
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 144,
                "End": 402
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 406,
                "End": 537
            },
            {
                "InterPro-ID": "IPR000277",
                "InterPro-Name": "Cys/Met-Metab_PyrdxlP-dep_enz",
                "InterPro-Type": "FAMILY",
                "Beg": 170,
                "End": 538
            },
            {
                "InterPro-ID": "IPR044639",
                "InterPro-Name": "CGS1/2",
                "InterPro-Type": "FAMILY",
                "Beg": 50,
                "End": 540
            }
        ],
        "ipr_mapped": [
            73,
            74,
            75
        ],
        "response#1": "MLWKQEREREREREREREERERERERERERERERERERERERESAASAASAASAASAASAASAASAASAARPPPPPPPPPPPPVPPAPPPPRRRRRRRRPPRPPPRRPPPPRQRPPPPRRPRPPPRRRRPPRPGRRPPRRPPGRRAPPHRRRALRAAAAAAAASSSSSSSSSSSSRSSSSSSSASAAAAAAAAAAAAAAAAAAAAAAAASSSSSSSSSSSSSSSAAAAAAAAAAPPPPRPPPPRRRRRRRRRRGGRRRSRSLSPSSSSSHSSSSSSSSSSSSSSRPPA",
        "response#2": "MHTTTSSSPSSPSPSPSPSSPSPSPSPSPSSPSPSPSSPSPSPSPSPSPLPSPSPSSSPSPSPSSPAATSSPSRPPSPSSPSPSAAAAAAAAAAAAAAAAAAPSTRRRARARRRRAAAAAAAAAARRTRPRRRRRPPSPAPAAPTSSPSASPSPSSPRRRRRAAAAARRRARRRRGARARRRRARRVGRRRRRRRRPSPSSSAAAAAAAAVAPAAASGRGSRRAASAARRRRRRRAKRRRAAPASPSPSPSPPSSPSSSTASAAAVGK",
        "response#3": "MKNFQNNKIFINSTQINSNIFEKNFSNNNFNQNLLNNNQIIFEKISKNQFLNFKRNEIDCKNKNFNFEKNFSKNFKFIDENKFNFFFNFQFQIKNLENVSKSLEIFKNFNQNQNFFLNFLKNFSFISIQINSLNEIFFLFNFRIFENKIKIKKNFNKKRKFFRKKENQKKFLFIKNKINLSKNNFLNFKENKNFKFNKTSNFQNQIENKENFLKKNQNLKKIKNIFKNKIFNQSENSFFFEKTFENFEKNFNLGIKFSFNFFENSNFSKNILKNFENNQNSFIFEIEISKIENFKTFFFEQKNKNFKFFFFNCRKNSENFKNFFLKSK"
    },
    {
        "reference": "MAENQEALAEFYDKGVGVWDNLSREHMHFGYYAPGATATIGGHRASLVRLIDEALCFAEFPDDPEKKPRNMLDVGCGIGGTCLHVAKKYDIQCKGINISPEQVKIAQGLAAAQGLESKVSFDVGDALDMPYPDGAFDLVLSIHCIEHLQDKEKFIREMVRVAASGATIIILSHVHRDLSPSEQSLKPQEERVLRKIGSSVQAWFCPLSNYVSLLAPLPVEVIKIADWSRNIDPSSRLMLKVAFSVKGIVSNLMKGVQGWTAIKNVLPMKLLHKALHDGLVKFVVLTCRKSN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 289
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 289
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013216",
                "InterPro-Name": "Methyltransf_11",
                "InterPro-Type": "DOMAIN",
                "Beg": 72,
                "End": 170
            },
            {
                "InterPro-ID": "IPR025774",
                "InterPro-Name": "MTs_g-TMT",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 196
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 289
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 289
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MNKVALYCRAGFEKECAAEITDKAGKLEIFGFARVKENSGYVIYELYQPEDGEKLIRELFFGGELLVEELPKEHSNFVRELTVPLRNALPMLEENPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQEQLAKKLQIQAKQLYHDREEVTVHVRRI",
        "response#2": "MDANTDKSCPTPLPQIRRKCRYELFHCTCFGWLVAARKKENSGEVLVEVADTNESKELLKFCRKFTVPLRAALRDAGVLSEENPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQEQLKENFQIQAKQLYHDREEVTVHVRRR",
        "response#3": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYELYQPDDGEKLIRELPFSSLIFARQWLVVLGQLPEPGNNRPIEVADTNESKELMKFCRKFTVPLRAALRDAGVLAEDPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGDR"
    },
    {
        "reference": "MAEKQQAVTEFYNNTSPRGAWEFLLGDHLHEGFYDPGTTATISGSQAAAARMIDEALRFANIYDDPSKKPKNMLDIGCGVGGTCVHVAKQYGIQCKGITLSPEEVKCAQGIAKAQGLEEKVSFDVGDALNLPYKDGTFDLVLTIECIEHVQDKEKFIREMIRVAAPGAPIVILSYAHRNLSPSAESLKPDEKKVLKKICDNLALSCLCSSADFVRWLTQLPAEDIKTADWTQNTSPFFPLLMKETFTWKGFTSLLMKGGWTAIKELLALRMMSKAADDGLLKFVAITCRKSK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 290
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 290
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013216",
                "InterPro-Name": "Methyltransf_11",
                "InterPro-Type": "DOMAIN",
                "Beg": 74,
                "End": 171
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 290
            },
            {
                "InterPro-ID": "IPR025774",
                "InterPro-Name": "MTs_g-TMT",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 292
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 5,
                "End": 290
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MAAGGGGGPAVGRRPAAGAARPAGCGGPAPGGPGGPAPPAGARAGRPVPPAHRGAHRRRGRAAGRRAHPPGGRPVRPRRPGGAPGPPGPGARPRPAPVRPGPVPTGAARAAAGTGPAGTDPGRAGPAGAHPGRRGPGAAGRGPGPGARRRHTGRRRGPRGDPAGRRRAGPAPPGAGRGRPGAPARHAGPRAGPAGRADAARRAPPPGRAGAGPGAAPAPAWCAAPPTR",
        "response#2": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGEKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVAEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSHNNSSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLLDDTGQVTWLREDGFRFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVR",
        "response#3": "ELLKFCRKFTVPLRAALRDAGVLANLETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQAKQLYHDREEVTVHVRRI"
    },
    {
        "reference": "MAGKSPEEQHPVKAYGWAARDSSGILSPFKFSRRATGDHDVRVKILYAGVCHSDLQSARNEMGCFTYPLVPGFETVGIATEVGSKVTKMKVGDKVAVGIMVGSCGKCDDCVNDRECYCPEVITSYGRIDHDGTPTYGGFSNETVANEKFVFRFPEKLPMAAGAPLLNAGVSVYSPMRFYGLDKPGMHLGVVGLGGLGHLAVKFAKAFGVKVTVISTSSIKKGEAINDLGADAFLVSTDAKQMQAGSGTLDGILDTVPVVHPIEPLLGLLKNHTKLVLVGATMGSFELPILPLGVGRKSVASTVGGSTTEAQEMLDFAAEHNITANVEIIPMDYINTAMERIEKNDVRYRFVIDVGNTLTPPES",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016616",
                "GO-Name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 322
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 9,
                "End": 357
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 24,
                "End": 352
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 157,
                "End": 322
            },
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 16,
                "End": 353
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 11,
                "End": 200
            },
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 195,
                "End": 318
            },
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 154
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MTTDTTRTDTTATDTTATATTATARRPARLAGKVALITGGASGIGEAAARLFAAEGARVVIADVAEEAGRRVAAEIPGAVFVRTDVTREDDVRALVAFAVERFGRLDVAFNNAGVAIAAPVHEITPEDWDRVMAVNLRGVFLCMKHEIRAMLAAGGGGSIVNASSVSGLIGAPGVAAYCASKHGVVGLTKAAALEYGPRGIRVNSLHPGTVETPMVERVAAARGRPVEEVRREMEAGHPLGRMARPEEVARAALYLASDEASFVTGAELVVDGGLTAHTAAG",
        "response#2": "MGRLDGKVAIITGAASGIGRAAALLFAREGAKVVVADLNEEGGKETEELIKKEGGEAVFVKTDVSKEEDVKRMVDTAVEKFGRLDIAFNNAGVEGKRKPVHETTEEDWDRVMAINLKGVWLCMKHEIKQMLKQGGGSIINASSIAGLVGNRMGYVPYVASKHGVVGLTKTAALEYASKGIRVNAIAPGIIETPLLKKAFEAAGEEAKKAVLASQPLNRIGKPEEVAYAALFLASDESSYITGVVLPVDGGQTAGRPFPVPYL",
        "response#3": "MRRLRLEGKVAVITGAASGLGEATARLFAAEGARVVLADLDEERGRRVAAELSVAGEAAFVRTDVSREEDVAALVRTAVERFGRLDVAFNNAGVVPAAPPAPPEGTPRPERIADLPLEVYDRVQAVNARGVFLCMKHEIRAMLEQGGGSIVNAASVAGLVGFPGVAAYVASKHAVVGLTRAAALEYADRGIRVNALAPGYVETPMTRAAMSDPAVRAALEQAIPLRRWGRPEEIAAAALWLASDESSYVTGVVLPIDGGYTA"
    },
    {
        "reference": "GSITTVLNATDIAKALAQCAGSFNHKTFFVTSGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGKIGVDEFKAMVKA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more EF_hand_dom, EF_hand_dom, EF_hand_dom, EF_hand_dom that are essential for its biological function; 2. The protein should be classified within EF-hand-dom_pair sharing conserved structural features; 3. The protein should include a EF_Hand_1_Ca_BS, EF_Hand_1_Ca_BS that enables ligand binding under diverse conditions; 4. The protein must be able to perform the calcium ion binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0005509",
                "GO-Name": "calcium ion binding "
            }
        ],
        "go_f_mapped": [
            31
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 50,
                "End": 62
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 106
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 89,
                "End": 101
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 72
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 80,
                "End": 107
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 69
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 105
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 50,
                "End": 62
            },
            {
                "InterPro-ID": "IPR011992",
                "InterPro-Name": "EF-hand-dom_pair",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 20,
                "End": 106
            },
            {
                "InterPro-ID": "IPR018247",
                "InterPro-Name": "EF_Hand_1_Ca_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 89,
                "End": 101
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 37,
                "End": 72
            },
            {
                "InterPro-ID": "IPR008080",
                "InterPro-Name": "Parvalbumin",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 106
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 80,
                "End": 107
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 69
            },
            {
                "InterPro-ID": "IPR002048",
                "InterPro-Name": "EF_hand_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 41,
                "End": 105
            }
        ],
        "ipr_mapped": [
            66,
            67,
            68
        ],
        "response#1": "MDLRPRQLLVLLCVVCFCLAKPTEKKDKKDKEHDHDHDHHHDHDHHHDHHKDHQHHKDHDHHKDHKPHHEPHHDHEKPKDHHHDHDHKHEKVHDAPLHSDAKLHDDSANFNYDHDAFLGAKDEAKTFDQLTPEESKERLGKIVEKIDGDHDGFVTVEELTDWIKYAQKRWIYENVERQWKGHDLNEDGLVSWEEYKNVTYGRYIDYDPAFDDPDDGFSYKQMLVRDERRFKMADKDGDLIANKEEFTAFLHPEEYDYMKEIVVLETMEDIDKNNDGFIDLEEYIGDMYSRDYDPNEDLGGVDDDANEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPADYDHMAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFARDEF",
        "response#2": "MDLRLLCVLLCLVACCLAKPKVKHDKVKHDKVKHDKVKHDKVKHDHDKVKHDKVKHDHDKVKHDKVKHDKVKQDEKHKDHHDKVHVDEHDVHYDHDAFLGAKKDAKTFDELTYEESLARDEKRFKMADKDSDLIATKEEFTAFLHPEEYDYMKDIVVLETFEDIDKNQDGLIDWEEYKNATYGSQYLDADAFELEGKDHNPADEFSYKQMVARDEKRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVLETMEDIDKNADGFIDLEEYIGDMYNHEGDEPEWVKTEREQFVEFRDKNKDGKMDKEETKDWILPSDYDHAEAEAKHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRDDAFVRHDEF",
        "response#3": "MDRRLVLLLCLVAVALAAPTKEKEKKDKCHEHHDKHHDDHHDDHHDNHEHHDDHHDDHHHDEHDHGKEEKTFHEGDSQNFAYDHEAFLGKEEAKTYDELTYEEMVARDEKRFKKADKDSDMFATKEEFTAFLHPEEYDYMKEIVALETMEDIDTNKDGFIDFEEYIAEHKIHTERDEKRFKKADKDGDMFATKEEFTAFLHPEEYDYMKEHVALETMEDIDTNKDGKLDKEEIVDKYDLFVGSQATNFGEALVRHHDEF"
    },
    {
        "reference": "MSTSNGSTENIQKPLRKIPDITGTPILTAIKDRLDFFYNQGQYEYFQSRVKKNNSTILRMNMIPGPFASNPKIVALCDAASFPTLFDPSKVSKVNSLTGNYMPALSFTGGYRVCAYLDPSEPTHTKIKQVFFNAQAAKKDTFIPTFVSTFNSMFDKMDAEVESKKKAEFTKFNEAAVFEFVGLALVGPKPAREVFDSAKKSVFFQFHPFITAGLPALVEELAFHMFPFPSFVAKSSYKILYEYFSTGGSWILDNAEEIGLSREEAIHHLIFTWAINAYLGIRTCLMRLFKWIVASGPDLQEKLAREVRSVVRSEEGKITFAGIEKMELVKSVAYESFRFDPPVQVQYGTAKSDLIIESHDGKYQVKKGEMLCGFQPMATRDPKVFDRADEFVPDRFMGDGKKLVKHVLWANGYGTDAPKADDKICAGKDLGVLVGRLLIAVMFLRYDKIGGVVGKTMEEVDVIVNELTKVAV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450_E_grp-IV, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein must be able to perform the heme binding,lyase activity,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0016836",
                "GO-Name": " hydro-lyase activity "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            32,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 377
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 326,
                "End": 342
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 425,
                "End": 443
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 379,
                "End": 397
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 294,
                "End": 402
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 450
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 447
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 363,
                "End": 377
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 326,
                "End": 342
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 425,
                "End": 443
            },
            {
                "InterPro-ID": "IPR002403",
                "InterPro-Name": "Cyt_P450_E_grp-IV",
                "InterPro-Type": "FAMILY",
                "Beg": 379,
                "End": 397
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 294,
                "End": 402
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 450
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 447
            }
        ],
        "ipr_mapped": [
            18,
            21,
            22
        ],
        "response#1": "MQQTILRLVAQMTSRVFVGLPLCRNEGWLKITVDYTTNVFMAAVEVNRVFPEFLRPIVHWFLPSCRTLRAQIAEAREIINPVLEERRRAKEEAMRRGEEVPQFNDTIEWFDEVAKGSEYDPAHVQLQLSVAAIHTTSDLLTQVMFDLCANPELIQPLREEVIRVINENGWKKTALYNLKLMDSVLKESQRLKPVLVLGMMRRVVQKDGTKLSDGTFIPKGTKINVSAHHMWKDESIYPDPDKFDGYRFYKLRQQPGKEENAHQFVSTSPDHLGFGHGKHACPGRFFASNEVKIALCHILLKYDFRFEDGEKPKIVNNGLFISADPSARIMVRRRKEEISLG",
        "response#2": "MSSRVFLGEELCRNEGWLKITTDYTVNSFTAAVELRVFPEILRPVVHWFLPSCRKLRAQIAEAREIINPVLEERRRMQEEARKKGEVPTYNDTIEWFEEVAKGSEYDPALAQLTLSVAAIHTTSDLLTQVMFDLCANPELIQPLREEIIRVINENGWKKTALYNLKLMDSVLKESQRLKPVALVTMRRMAMKDVTLSDGTFIPKGGHVMVSAHSMGHDPDIYPDPEKFDGYRFYKMRESGEENSAQLVSVSPDHLGFGLGKHACPGRFFASNEIKIALCHILLKYDFKFADGEKPKMLSSGFFLHADPSARIMVKRREVEI",
        "response#3": "MLHIVAQMSSRVFLGLPLCRNEAWLKITTDYTVNVFTAVEELRKWPEFLRPIVHWFLPSCKKLRAQVAEARELINPVIAERRREQAAYREDGKKVFNDAIQWFEDNAKGEESYDPALAQLTLSVAAIHTTSDLLTQVMFDLCANPELIQPLREEIIEVLGVLSATGAIPTIKKTSLYKLKLMDSVLKESQRLKPPVQVMNRMVTKDVTLSDGTVIPKGVRISIPAHAMSHDPSIYPDPEKFDGYRFVRLREQAVAAGTPGKENAHQLVSTSPDFLGFGHGKHACPGRFFASNEVKIALCHILLKYDFRFPEENEGRKPEIVLDGLFIAADPSARLMVKRRV"
    },
    {
        "reference": "MFPMQFTNSAYRQMEPMFAPGPRGQVQPYRPRTKRRQEPQVGNAAIAALANQMSALQLQVAGLAGQARVDRRGPRRVQKSKQKKKNPSNGEKPKEKKKKQKQQEKKGSGGVIKKPRNRPGKEVRISVKRARQSTFPVYHDGAISGYAVLIGSRVFKPAHVKGKIDHPELADIKFQVAEDMDLEAAAYPKSMRDQAAEPATMMDGVYNWEYGTIRVEDNVVIDASGRGKPGDSGRAITDNSGKVVGIVLGGGPDGRRTRLSVIGFDKKMKAREIAYSEAIPWTRAPALLLLPMVIACTYNSNTFDCSKPSCQDCCITAEPKKAMAMLKDNLNDPNYWDLLIAVTTCNSARKKRAVSTSPAAVYDTQILAAHAAASPYRAYCPDCDGTACISPIAIDEVVSSGSDHVLRIRVGSQSGVTAKGGAAGETSLRYLGRDGKVHAADNTRLVVRTTAKCDVLQATGHYILASCPEGQSITVAATLDGTRHQCTTVFEHQVTEKFTRERSKGHHLSDLTKKCTRFSTTPKKSAPYLVDVYDALPISVEISTVVTCNDNQCTVKVPPGTTVKFDKKCKSAAQATVTFTSDSQTFTCEEPVLTAASITQGKPHLRSSMLPSGGKEVKARIPFPFPPETATCRVSVAPLPSITYEESDVLLAGTAKYPVLLTTRNLGFHSNATSEWIQGKYLRRIPVTPQGIELTWGNNAPLHFWSSVRYASGDADAYPWELLVHHTKHHPEYAWAFVGVACGLLVIAVCMFACACNRVRYSLVANTFNPNPPPLTALTAALCCIPGARADQPYLDIIAYLWTNSKVAFGLQCAAPVACVLIVTYALRHCRLCCKSFLGVRGWSALLVILAYVQSCKSYEHTVVVPMDPRAPSYEAVINRNGYDPLKLTIAVNFTVISPTTALEYWTCASVPIVEPPHVGCCTSVSCPSDLSTLHAFTGKAVSDVHCDVHTNVYPLLWGAAHCFCSTENTQVSAVAATVSEFCAQDSERAEAFSVHSSSVTAEVLVTLGEVVTAVHVYVDGVTSARGTDLKIVAGPITTDYSPFDRKVVRIGEEVYNYDWPPYGAGRPGTFGDIQARSTNYVKPNDLYGDIGIEVLQPTNDHVHVAYTYTTSGLLRWLQDAPKPLSVTAPHGCKISANPLLALDCGVGAVPMSINIPDAKFTRKLKDPKPSALKCVVDSCEYGVDYGGAATITYEGHEAGKCGIHSLTPGVPLRTSVVEVVAGANTVKTTFSSPTPEVTLEVEICSAMVTCASECTPPKEHVVATRPRHGSDTGGYISGPAMRWAGGIVGTLAVLFLILAVTYCVVKKCRSKRIRIVKS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Peptidase_S1_PA_chymotrypsin, Peptidase_S1_PA, Peptidase_S1_PA_chymotrypsin, Ig_E-set sharing conserved structural features; 2. The protein must be able to perform the serine-type endopeptidase activity,structural molecule activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004252",
                "GO-Name": "serine-type endopeptidase activity"
            },
            {
                "GO-ID": "GO:0005198",
                "GO-Name": "structural molecule activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004252",
                "GO-Name": "serine-type endopeptidase activity "
            },
            {
                "GO-ID": "GO:0005198",
                "GO-Name": " structural molecule activity "
            }
        ],
        "go_f_mapped": [
            38,
            68
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR043504",
                "InterPro-Name": "Peptidase_S1_PA_chymotrypsin",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 126,
                "End": 196
            },
            {
                "InterPro-ID": "IPR009003",
                "InterPro-Name": "Peptidase_S1_PA",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 127,
                "End": 281
            },
            {
                "InterPro-ID": "IPR043504",
                "InterPro-Name": "Peptidase_S1_PA_chymotrypsin",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 199,
                "End": 281
            },
            {
                "InterPro-ID": "IPR014756",
                "InterPro-Name": "Ig_E-set",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1167,
                "End": 1264
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR038055",
                "InterPro-Name": "Glycoprot_E_dimer_dom",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1085,
                "End": 1165
            },
            {
                "InterPro-ID": "IPR038055",
                "InterPro-Name": "Glycoprot_E_dimer_dom",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 987,
                "End": 1054
            },
            {
                "InterPro-ID": "IPR042306",
                "InterPro-Name": "Alphavir_E2_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 635,
                "End": 707
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 133,
                "End": 281
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 133,
                "End": 271
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 145,
                "End": 169
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 170,
                "End": 194
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 244,
                "End": 270
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 219,
                "End": 243
            },
            {
                "InterPro-ID": "IPR000930",
                "InterPro-Name": "Peptidase_S3",
                "InterPro-Type": "DOMAIN",
                "Beg": 124,
                "End": 137
            },
            {
                "InterPro-ID": "IPR000936",
                "InterPro-Name": "Alpha_E2_glycop",
                "InterPro-Type": "FAMILY",
                "Beg": 375,
                "End": 784
            },
            {
                "InterPro-ID": "IPR036253",
                "InterPro-Name": "Glycoprot_cen/dimer_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 859,
                "End": 1165
            },
            {
                "InterPro-ID": "IPR043504",
                "InterPro-Name": "Peptidase_S1_PA_chymotrypsin",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 126,
                "End": 196
            },
            {
                "InterPro-ID": "IPR038055",
                "InterPro-Name": "Glycoprot_E_dimer_dom",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 859,
                "End": 952
            },
            {
                "InterPro-ID": "IPR009003",
                "InterPro-Name": "Peptidase_S1_PA",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 127,
                "End": 281
            },
            {
                "InterPro-ID": "IPR043504",
                "InterPro-Name": "Peptidase_S1_PA_chymotrypsin",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 199,
                "End": 281
            },
            {
                "InterPro-ID": "IPR042305",
                "InterPro-Name": "Alphavir_E2_B",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 540,
                "End": 597
            },
            {
                "InterPro-ID": "IPR042304",
                "InterPro-Name": "Alphavir_E2_A",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 370,
                "End": 634
            },
            {
                "InterPro-ID": "IPR002533",
                "InterPro-Name": "Alpha_E3_glycop",
                "InterPro-Type": "DOMAIN",
                "Beg": 296,
                "End": 352
            },
            {
                "InterPro-ID": "IPR002548",
                "InterPro-Name": "Alpha_E1_glycop",
                "InterPro-Type": "DOMAIN",
                "Beg": 794,
                "End": 1309
            },
            {
                "InterPro-ID": "IPR014756",
                "InterPro-Name": "Ig_E-set",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1167,
                "End": 1264
            },
            {
                "InterPro-ID": "IPR000336",
                "InterPro-Name": "Flavivir/Alphavir_Ig-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1166,
                "End": 1266
            }
        ],
        "ipr_mapped": [
            476,
            86,
            87
        ],
        "response#1": "MKYLIILAALTSALALLPIAATAATTSTSAGSNSNSSSSANSNANSASNANSNASNANSNTSATTGTSANANTSTSSTSANTNASASSNTSTSASSSANTNSSTSTSSTSNSSANSNSNASANNANSNASATTTNSANTNANTSTSTNANTSSNTSSSTSTSTTNTSANTSTTSTTNSSSSTNTSTSASASGSANSSTTTSTNANTNAATNSNSNTSTNTNSNANSNTSTNANTNTSTSVTTASAATTAANAATATTAAATSAANTAATASNTNASANSSANTNTATATNSNATNTHSSSTSSNNANATSNTNTSANTTNAILNANFCAS",
        "response#2": "MARRGGAGPRRPRPGDARAAGAGGDRAGPSPGRGRAPGAPAAAGRRPRGRVRGAAAGGAGGRPGRAAPRPGRAGRGPAGARRGRGPGPRRPGPARGPAPPRGRRPAAGPAGPRRGRPGRGRGAGRRAPAGRGPGRAPAGRRAGPGRPAARGGGPAAGDPRPDPFRRAAGRARRSTRAPGTPGAGRADAGRPGPAPARPRPGRPGPAAGRPATGLTGSGRPGAGPAGPGAPGRSPGRPRPGRTGRGRGGPGRARPAGPAAGPAGRGPAGPTARPGADARTGPGRAPATRPGRRAAGRVGGRRSGRAGAGARGRGRAAAGPGGRRVAGAARGPAAGPAPGRGPAAPPGAGAGPGVPVPGAPAGPGPPGRRPEPAAPPALFPDEAAPGPAGGPGRPGRE",
        "response#3": "MLPPPAPGAAPGARGRAGAPRGAGARGARGGVPPARGGGPAARRGPRGRGREGAGPPAPRPGPGRGPGRPGRGAGGARRAGAPRPPPLLGRPAAGARAPAPRRPPGPPPPAPRLPAARRGPARAGGGAGPGPPRSPPRAPPRGPAGARGAGARGGPAPGRGGARAARAPGGGVPARAARRGGLPLPAPRPRAPGGSPRRAAAPRGAPLPPGPGGGAGPGAGWRGLPAPAPARAAPGVGGAPRGAGPRGARAGRGRAGAPTRAGGP"
    },
    {
        "reference": "MDDLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTEPRPPPRRIAVPSRGPTSVPKPAPQPYAFSTSLSTINFDEFSPMVLPPGQISNQALALAPSSAPVLAQTMVPSSAMVPSLAQPPAPVPVLAPGPPQSLSAPVPKSTQAGEGTLSEALLHLQFDADEDLGALLGNNTDPGVFTDLASVDNSEFQQLLNQGVAMSHSTAEPMLMEYPEAITRLVTGSQRPPDPAPATLGTSGLPNGLSGDEDFSSIADMDFSALLSQISS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Ig-like_fold, Ig_E-set sharing conserved structural features; 2. The protein must be able to perform the nucleic acid binding,nucleic acid binding,DNA-binding transcription factor activity,DNA-binding transcription factor activity,DNA-binding transcription factor activity,DNA-binding transcription factor activity,nucleic acid binding,identical protein binding,phosphate ion binding,protein homodimerization activity,transcription cis-regulatory region binding,transcription cis-regulatory region binding,transcription cis-regulatory region binding,sequence-specific DNA binding,transcription cis-regulatory region binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003676",
                "GO-Name": "nucleic acid binding"
            },
            {
                "GO-ID": "GO:0003676",
                "GO-Name": "nucleic acid binding"
            },
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0003700",
                "GO-Name": "DNA-binding transcription factor activity"
            },
            {
                "GO-ID": "GO:0003676",
                "GO-Name": "nucleic acid binding"
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": "identical protein binding"
            },
            {
                "GO-ID": "GO:0042301",
                "GO-Name": "phosphate ion binding"
            },
            {
                "GO-ID": "GO:0042803",
                "GO-Name": "protein homodimerization activity"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            },
            {
                "GO-ID": "GO:0043565",
                "GO-Name": "sequence-specific DNA binding"
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": "transcription cis-regulatory region binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0042805",
                "GO-Name": "actinin binding "
            },
            {
                "GO-ID": "GO:0071532",
                "GO-Name": " ankyrin repeat binding "
            },
            {
                "GO-ID": "GO:0003682",
                "GO-Name": " chromatin binding "
            },
            {
                "GO-ID": "GO:0031490",
                "GO-Name": " chromatin DNA binding "
            },
            {
                "GO-ID": "GO:0003677",
                "GO-Name": " DNA binding "
            },
            {
                "GO-ID": "GO:0001228",
                "GO-Name": " DNA-binding transcription activator activity, RNA polymerase II-specific "
            },
            {
                "GO-ID": "GO:0003700",
                "GO-Name": " DNA-binding transcription factor activity "
            },
            {
                "GO-ID": "GO:0000981",
                "GO-Name": " DNA-binding transcription factor activity, RNA polymerase II-specific "
            },
            {
                "GO-ID": "GO:0140297",
                "GO-Name": " DNA-binding transcription factor binding "
            },
            {
                "GO-ID": "GO:0001227",
                "GO-Name": " DNA-binding transcription repressor activity, RNA polymerase II-specific "
            },
            {
                "GO-ID": "GO:0003690",
                "GO-Name": " double-stranded DNA binding "
            },
            {
                "GO-ID": "GO:0019899",
                "GO-Name": " enzyme binding "
            },
            {
                "GO-ID": "GO:0140296",
                "GO-Name": " general transcription initiation factor binding "
            },
            {
                "GO-ID": "GO:0042826",
                "GO-Name": " histone deacetylase binding "
            },
            {
                "GO-ID": "GO:0042802",
                "GO-Name": " identical protein binding "
            },
            {
                "GO-ID": "GO:0051059",
                "GO-Name": " NF-kappaB binding "
            },
            {
                "GO-ID": "GO:0042277",
                "GO-Name": " peptide binding "
            },
            {
                "GO-ID": "GO:0042301",
                "GO-Name": " phosphate ion binding "
            },
            {
                "GO-ID": "GO:0042803",
                "GO-Name": " protein homodimerization activity "
            },
            {
                "GO-ID": "GO:0019901",
                "GO-Name": " protein kinase binding "
            },
            {
                "GO-ID": "GO:0044877",
                "GO-Name": " protein-containing complex binding "
            },
            {
                "GO-ID": "GO:0000978",
                "GO-Name": " RNA polymerase II cis-regulatory region sequence-specific DNA binding "
            },
            {
                "GO-ID": "GO:0000979",
                "GO-Name": " RNA polymerase II core promoter sequence-specific DNA binding "
            },
            {
                "GO-ID": "GO:0000977",
                "GO-Name": " RNA polymerase II transcription regulatory region sequence-specific DNA binding "
            },
            {
                "GO-ID": "GO:0043565",
                "GO-Name": " sequence-specific DNA binding "
            },
            {
                "GO-ID": "GO:0000976",
                "GO-Name": " transcription cis-regulatory region binding "
            },
            {
                "GO-ID": "GO:0001223",
                "GO-Name": " transcription coactivator binding "
            },
            {
                "GO-ID": "GO:0031625",
                "GO-Name": " ubiquitin protein ligase binding "
            }
        ],
        "go_f_mapped": [
            116,
            116,
            160,
            160,
            160,
            160,
            116,
            27,
            290,
            37,
            91,
            91,
            91,
            159,
            91
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR013783",
                "InterPro-Name": "Ig-like_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 191,
                "End": 304
            },
            {
                "InterPro-ID": "IPR014756",
                "InterPro-Name": "Ig_E-set",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 191,
                "End": 322
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR030492",
                "InterPro-Name": "RHD_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 34,
                "End": 40
            },
            {
                "InterPro-ID": "IPR000451",
                "InterPro-Name": "NFkB/Dor",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 442
            },
            {
                "InterPro-ID": "IPR032397",
                "InterPro-Name": "RHD_dimer",
                "InterPro-Type": "DOMAIN",
                "Beg": 195,
                "End": 291
            },
            {
                "InterPro-ID": "IPR013783",
                "InterPro-Name": "Ig-like_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 191,
                "End": 304
            },
            {
                "InterPro-ID": "IPR002909",
                "InterPro-Name": "IPT_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 193,
                "End": 289
            },
            {
                "InterPro-ID": "IPR011539",
                "InterPro-Name": "RHD_DNA_bind_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 16,
                "End": 190
            },
            {
                "InterPro-ID": "IPR033926",
                "InterPro-Name": "IPT_NFkappaB",
                "InterPro-Type": "DOMAIN",
                "Beg": 194,
                "End": 290
            },
            {
                "InterPro-ID": "IPR011539",
                "InterPro-Name": "RHD_DNA_bind_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 21,
                "End": 186
            },
            {
                "InterPro-ID": "IPR030495",
                "InterPro-Name": "RelA_RHD_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 19,
                "End": 187
            },
            {
                "InterPro-ID": "IPR000451",
                "InterPro-Name": "NFkB/Dor",
                "InterPro-Type": "FAMILY",
                "Beg": 208,
                "End": 228
            },
            {
                "InterPro-ID": "IPR000451",
                "InterPro-Name": "NFkB/Dor",
                "InterPro-Type": "FAMILY",
                "Beg": 239,
                "End": 257
            },
            {
                "InterPro-ID": "IPR000451",
                "InterPro-Name": "NFkB/Dor",
                "InterPro-Type": "FAMILY",
                "Beg": 175,
                "End": 189
            },
            {
                "InterPro-ID": "IPR000451",
                "InterPro-Name": "NFkB/Dor",
                "InterPro-Type": "FAMILY",
                "Beg": 280,
                "End": 294
            },
            {
                "InterPro-ID": "IPR000451",
                "InterPro-Name": "NFkB/Dor",
                "InterPro-Type": "FAMILY",
                "Beg": 25,
                "End": 42
            },
            {
                "InterPro-ID": "IPR008967",
                "InterPro-Name": "p53-like_TF_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 18,
                "End": 196
            },
            {
                "InterPro-ID": "IPR014756",
                "InterPro-Name": "Ig_E-set",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 191,
                "End": 322
            },
            {
                "InterPro-ID": "IPR037059",
                "InterPro-Name": "RHD_DNA_bind_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 187
            }
        ],
        "ipr_mapped": [
            475,
            476
        ],
        "response#1": "MLSEERLEAALDEDAVDGGEPGDPDGGPGDGAAFEPWTAPPGGSGGGSDGDRGRGAPAGAGAGRGDGREPRYLGDGSEGGGVRGRALRAGAAGAGALGWRAPAGGAVRLDGTRFADPGPGGGGGAGGDAEGGPAGGAGAGERAEAEVVRLRQRLFDAEREELVGELERLARARADALARGASVRARPRGSGSAARARGRALAEDPGGAGLDD",
        "response#2": "MLEGERLDREAVEDPDGAERLEGAGDAPGPRTLPDRALDDADGGGVVEQGGSGTLDAAGSGAGALAAWGLDGASFDGALADGGDAAAAPLGAPGPVGAESRDDLEAREATGGGGGLEALDGASALREQDAGALDGPLGSLDGAGGGAGGGDRAEAGRRALLADGRRGQGEGRAVGLPRAADLASGRGAEGGRPAPPDDRADGARAEGGSDGPRGRAVEPRSRAGTAREADARAREAAEPRDEGLGELEPGPAGGGGAARERPGERDPGGATGVTLDAAPGPEGG",
        "response#3": "MLEETYRSPETEGASEPGGTGEGDAERDPVRDRALAGETRSAENDPAGSGDDLEADGGRGADGAEGAAGGGDEPSPAASLATETLEEIAADGGRVATLGGADVGEETEAGLASDAPAPGEPGRGGSVAAGPGEGGGPADAGAARVAPKSRGIDAPGAALAETLARELDGGERSARAPDGGAADDAATARGADPAGVRREAAGEGAGAPARGVDAAGGADGGDAREPPLAGEPVEEEVWAGDDGATAGGDGGGAEAAGGPRAGGGEAAPADGGGVRVLLGPPDAGERGDPRPGIALPETGGG"
    },
    {
        "reference": "MNQFNKVCVIGLGYIGLPTAAIFASRKIKVIGVDINQNIVDIINKGKIHIVEPGLDILVHMVVNDGYLKATTLPEEADAFIIAVPTPFKGDNHEPNLDYIEMASKAIAKVLKKGNLVILESTSPVGTTEQMAKWLAEERSDLSFPHQCGEVSDIKIAHCPERVLPGQVIRELVENDRIIGGMTQKCAEYAIRLYKIFVQGECIMTNARTAEMTKLTENSFRDLNIAFANELSILCDKLDINVWELIKLANRHPRVNILQPGCGVGGHCIAVDPWFIVYQNPNEAKIIKTAREVNDNKPNFVVQKIKKKIKDILGPKIACLGLAFKPDIDDLRESPALDIVIKLASENASQILVVEPNIKQLPLKLQNKRNIKLVCLSQALDEADVVAVLVRHKEFIEVQSDKVVSFC",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf, 6-PGluconate_DH-like_C_sf sharing conserved structural features; 2. The protein must be able to perform the NAD binding,oxidoreductase activity,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0051287",
                "GO-Name": "NAD binding "
            },
            {
                "GO-ID": "GO:0016628",
                "GO-Name": " oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor "
            },
            {
                "GO-ID": "GO:0003979",
                "GO-Name": " UDP-glucose 6-dehydrogenase activity "
            }
        ],
        "go_f_mapped": [
            22,
            4,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 200
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 208,
                "End": 300
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR028359",
                "InterPro-Name": "UDP_ManNAc/GlcNAc_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 406
            },
            {
                "InterPro-ID": "IPR014027",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 318,
                "End": 402
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 6,
                "End": 200
            },
            {
                "InterPro-ID": "IPR017476",
                "InterPro-Name": "UDP-Glc/GDP-Man",
                "InterPro-Type": "FAMILY",
                "Beg": 5,
                "End": 406
            },
            {
                "InterPro-ID": "IPR014026",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_dimer",
                "InterPro-Type": "DOMAIN",
                "Beg": 208,
                "End": 295
            },
            {
                "InterPro-ID": "IPR028359",
                "InterPro-Name": "UDP_ManNAc/GlcNAc_DH",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 397
            },
            {
                "InterPro-ID": "IPR008927",
                "InterPro-Name": "6-PGluconate_DH-like_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 208,
                "End": 300
            },
            {
                "InterPro-ID": "IPR036220",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_C_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 304,
                "End": 400
            },
            {
                "InterPro-ID": "IPR001732",
                "InterPro-Name": "UDP-Glc/GDP-Man_DH_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 6,
                "End": 189
            },
            {
                "InterPro-ID": "IPR017476",
                "InterPro-Name": "UDP-Glc/GDP-Man",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 402
            }
        ],
        "ipr_mapped": [
            503,
            7
        ],
        "response#1": "MADFLVSQPCSASSDGPPSSSDPPPSSSSSSSSSPSPPAAAASPAATAGAAAAAAAAAPARLRGKVAFITGAASGLGLATARLLLAAGAQVVLADVDAARGAAAAAALAGELGPEARVRFVPADVTRAEQVDVAVAAALAAFGRLDAAFNNAGIVRDKPVNTYTEADFDDVISVNLKGVFLGMRAVALAMRPHGAGSIVNTYTEADFDDVISVNLKGVFLGMRAVALAMRPHGAGSIVNTASIMGLVGNPGQANYCASKLGVVGLTKTAALELGPSGVRVNAIAPGFIETPMTAPVLADAARRAAVAAAVPLGRMGRPEEVARAALFLASDDSSFVTGAVLAVDGGYTASLAPPPAPPSGPPGPAAPQQEEQQQ",
        "response#2": "YPRSRRICIRDLSASRRRAVQWRGPLEKLAVRAGEVATSSLAEQKSMASLKDKVAIVTGASRGIGAAIARALAAAGAKVAVNYASNELAAKAVVAEIEAAGSGRALAIRADVSKEAEVAAMVEQTVAAFGGLDIMVNNAGILRDATVTNMTEEDWDRVIAVNLKGTILGMKHAGRQMLKQRSGSIVNISSMSGLVGNRGQANYSATKHGVVGLTEAAAWEM",
        "response#3": "MSLTDKVVAITGATSGLGEATARLFASHGAKVALAGRRQDRLDALASAIQSSSPTAKVLAVAIDVTKTSEVETWVAKTVEHFGRLDVAFNNAGVALDFSKPLHEVEEEDFDRLMAVNVKGVVLGMKYEIQQMLKQNGGEEKGSIVNTSSIAGFVGGFASPLYTATKHAVVGLTKSAALFHAKDRIRVNAIAPGFVNTPLTGPLLQTEEGKKMMDEMVPMKRALEPVEVAEAALFLASDKASYVTGQVLCVDGGFTAVSSVQSASTSYISTHGRSVVVLPEPPSPTHYAFMREKVAGKKEVDKRMTAAFLKSVFTSALTKEEIEKAQKEAEKDATGDDEDD"
    },
    {
        "reference": "MAKSPEVEHPVKAFGWAARDPSGVLSPFNFSRRATGEHDVQFKVLYCGICHSDLHMIKNEWGFTKYPIVPGHEIVGVVTEVGSKVEKFKVGDKVGVGCLVGSCRKCDMCSDDLENYCPGQILTYSAAYTDGTTTYGGYSNLMVSDEHFVICWPENLPMDIGAPLLCAGITTYSPLRYFGLDKPGTHVGVVGLGGLGHVAVKFAKAFGAKVTVISTSESKKQEAIEKLGADAFLVSRDPEQMQGAAGSMDGIIDTVSAVHPVLPLVNLLKSQGKLIMVGAPEKPLELPVFPLLAGRRIIAGSAIGGLKETQEMIDFAAKNNILPDVELVPMDYVNTAMERLLKADVKYRFVIDIGNTLKSA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 2. The protein must be able to perform the oxidoreductase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0045551",
                "GO-Name": "cinnamyl-alcohol dehydrogenase activity "
            },
            {
                "GO-ID": "GO:0008270",
                "GO-Name": " zinc ion binding "
            }
        ],
        "go_f_mapped": [
            4,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 156,
                "End": 321
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR013154",
                "InterPro-Name": "ADH-like_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 36,
                "End": 153
            },
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 14,
                "End": 352
            },
            {
                "InterPro-ID": "IPR020843",
                "InterPro-Name": "PKS_ER",
                "InterPro-Type": "DOMAIN",
                "Beg": 23,
                "End": 351
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 156,
                "End": 321
            },
            {
                "InterPro-ID": "IPR047109",
                "InterPro-Name": "CAD-like",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 356
            },
            {
                "InterPro-ID": "IPR002328",
                "InterPro-Name": "ADH_Zn_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 71,
                "End": 85
            },
            {
                "InterPro-ID": "IPR013149",
                "InterPro-Name": "ADH-like_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 194,
                "End": 317
            },
            {
                "InterPro-ID": "IPR011032",
                "InterPro-Name": "GroES-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 19,
                "End": 185
            }
        ],
        "ipr_mapped": [
            7
        ],
        "response#1": "MKTIVITGASSGIGLETAKKFLKEGFKVVGLDLQEPKEEIKNNENFLFVKVDVTKEEEVKNAIKTAVEKFGKIDALVNSAGIEIRKPIEEHTEEDWDKIMAINAKGTFLVTKHALPHLENGSIVNISSIAGVIGEYGLSAYVASKHGVIGFTKSLAVEYSKKGIRVNAVCPGWIDTPMTAKLLENPERKEYIKNTIPMGRLGTPEEVAEAI",
        "response#2": "MAPPRRRRPRRPRRPRPRPPRRRRRRPPRRRPRRRPRRPRRPRPRPPRRRPRRRPRRPRRPRPRPPRRHPRRPPRRRPRRPPRRRPRPPRREPPVGRLDGRVAVVTGSARGIGRAVAERFLREGAAVVGADLDDPGEGIADDRYLFLRTDVTDEDSVAAAVAAAVDRFGRLDVLVNNAGVAGPGAPVTDTDEAEWDRVLAVNLRGTFLCTKHAARAMIPAGAGSIVNTASIAGLVGFASRAAYTASKHGVVGLTRSAALELAAHGVRVNAVAPGPIDTPLLADHPERRARLVSRIPLGRLGRPEEVAAAYLFLASDEASYVTGAVLPVDGGVTAGGL",
        "response#3": "MARKVLVTGGAGFIGSHVVEALLERGYRVVNLDNLSTGDPRNVAHLMGREGYRFVRGDVADRELVERVFAEEGPFEGVIHLAALVGGIRYNVENPALFVRVNVEGTLNLLDAARRHGVRRFVFASSSSVYGEPSPEPQDEHHPYREDDPTRPLSPYGKSKLLAEKYVRESGLEYVILRYFNVYGPRDPHLYKFITQALRGEPLRVYGDGEQTRDFVYVEDVVEATLRALEAPRGHEVFNLGTGEETTMRRLAETVKELTGSRARIEFVPMPPERPRPGDVRRRRADISKARRVLGYAPRVSLEEGLRREVEWIRRHPG"
    },
    {
        "reference": "MNNDEQLEFLINYLLDERSESIDIPKTFSEKRNLLRSLMNMRHPSNISEEFLRIQDEFLSRETANKNLTSVEDISLSSGKIMLWQGDITTLSADAIVNAANSKLLGCFIPMHNCIDNIIHSASGLQLREECNRMIMLQGGDEDVGKAKITNAYNLPSKYVVHTVGPSIERGMRVSSDDVKKLERCYNSCLELASEYKLNSIAFCCISTGVFNFPQKKAAEIAIRTVKDFLNSNETSLNHIIFDVFTDKDYDIYKKLLFGN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Macro_dom-like, Macro_dom-like sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            19,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 79,
                "End": 257
            },
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 259
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002589",
                "InterPro-Name": "Macro_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 68,
                "End": 260
            },
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 79,
                "End": 257
            },
            {
                "InterPro-ID": "IPR002589",
                "InterPro-Name": "Macro_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 80,
                "End": 222
            },
            {
                "InterPro-ID": "IPR043472",
                "InterPro-Name": "Macro_dom-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 12,
                "End": 259
            },
            {
                "InterPro-ID": "IPR002589",
                "InterPro-Name": "Macro_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 97,
                "End": 222
            }
        ],
        "ipr_mapped": [
            96
        ],
        "response#1": "MTTATTSAAASAAASAAASAAASAAAADAADAADAPDAPDVPDAADAADAADAADAADAADAADAPDAPRPRTAARTAARTAPRTAARTAPRSAPRPPPRPTRPHRPPQRPHRPHRPPHPPHRTPDRPPTRPPDRPPTRPPPPPDRPATRPPHRPATRPPDRPPTRPPPPTRPPPHRPPPHRPTPRARPRPPRPTPHRPTPTRPTPTRRARTDRPARTARPARPAPTARPARPARTARTARTARTARTTPTARPTRTPTHRPPPPPTTPTPRTRTTPRPAPRPPRPRTTTATTATATTATATTATTAATTTATSTATATTTATTTTATTNTATSTGTGTATTGTGRTTRTARTGTPHRTRTTHRTTHRTRTTHRTTHRTAHHTAPRTAPTASAP",
        "response#2": "MYLAAAAAAAAAAAAAAAAAAAPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTTTTTTTTTTTTTTAAAAAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSGGGGGGGGGGGGGGGGGGGGGGGAAAAAAAAAAAAAAAYDR",
        "response#3": "IIYYNINNIYNIYIYKYIMLNKIIVKNIYNILIKNKLNKIIKYYTYYIYKYYKNKKIIYMNIIYIYNIKKIKPKNKIIKKNNKKYYNKIIIKNKILNKKYNKINYIKLYKLNKKKYLYIKKYKINNIYINNNLINNILNKIKNINKKLYKKKKKYKYKYNKYNNNIYLNNIINKYKLKKKYNKINIYNKYIINKLNNNINNIINIYNIINKNNKYIIYNRYNKYNYIYKKKNIYKYKYQYILYNNIYKIYYLLYKKYLNKYNLYINKFYNNNKYYILNNNLYNYKYKNINYKYYIKYNYINILKYNKINSIYNYIYYYNKIKIFSKKYILKKKIIIHLNKKLNLINSINLINLNNTIKYIYLTNYKNKTLYLNNININYIKLLKKKI"
    },
    {
        "reference": "MGSASGSAERTQMGEDEACSFAMTITSGSVPPMVLKAVIELDVLEIIKRAGPGAHLSPAEIAAQLPTTNPGAAAMLDRMLRLLASYDVLSYSLHTLPDGRVERLYGLAPVCQFLTNNEDGVTLSALSLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNNGMSNHSTITMKKLLENYKGFEGVSTLVDVGGGTGATLNMIISKHPTIKGINFDLPHVIEDAPTYPGVEHIGGDMFVSVPKGDAIFMKWICHDWSDEHCLRFLKNCYAALADHGKVIVCEYILPVAPETNHAARTVFHVDAIMLAHNPGGKERTEQEFESLAKGAGFEGFRVACSAYDTKVMEFLKNN",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 115,
                "End": 362
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 120,
                "End": 353
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 115,
                "End": 362
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 120,
                "End": 353
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 118
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 114
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 362
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 139,
                "End": 344
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 15,
                "End": 116
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 344
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 23,
                "End": 362
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MAQTTRPVQQPPLPQQQQQQQQQQQQPQQQQQQQQQQPQQQPQPPPPPQRAMDLTAATMPMALAPAAVEDPRGRDNDRDSAYAPSETASTTSLSSSIMQYRQENGRTYHAYRYKEGKYFLPNDETEQDRLDLQHHIFTLTLNGKLYLAPIGSGVQRALDVGTGTGIWAIDMGKNFGCQVTGIDLSPIQPSLIPPNCRFFVHDIEEPWTLPAGSMPWDNNFDLVHQRLMVGSIDPNNDWPKYLSQLFRVLKPGGWLELVEIDFAPDNPGPNLTKWCNLLIEASEKFGRPLRVDRHLKGMLVDAGFVDVVETRIVLPLNPWDPKYKELGRWFNLNLTEGLEALSMAPLTRALGWTPDEIRVFCVDVRKELKNRNIHAYSNIHVIYARKPY",
        "response#2": "MGTAVMVAAARAVATRRPDALINDPYAEPLVRAVGVDLVTRLDDEGFDMQRTADAMAIRTRYFDDFFLDATAAGIRQAVILASGLDSRAYRLPWPDTTVYEIDQPKVIEFKTATLAEPPTADRRTVAIDLRDDWPAALQKAGFDPTRPTAWSAEGLLIYLPPEAQDRLFDNITALSAPGSRLATEAMPDITTFDHERARAMAERWRKHGFDLDMAELVYHGERNDVAGYLRDHGWRVTSSPAGNDNPTTYVSAVLDR",
        "response#3": "MAAAPPPPPQPQPQPPQPQDRILVDADDAVFDSRSIASSTTSLASSILQYRFENGRTYHRYKEGKYNFPNDETEQDRLDLQHHLFTLTLDGKLYLAPIGCNPQRILDVGTGTGIWAIDMADQFPSAQVIGIDLSPIQPDDSEPKSASVPPNVRFEIDDVEEDWTYPKDHFDLIHIRMLTGSIADWPRLYRQALDHLKPGGYFEQVEIDFIPRSDDDTLPPDSALAKWSNLLIEASDKFGRTLRVAPLSKGWMVEAGFVDVVETVFKWPLNPWPKDPKLKELGRWFNLNLLEAIEALSMAPLTRAHGWTPSEIQVLLVDVRKDLKNRRIHAYTNIHVVYGRKPSSTSSGASLYATTTASDSVNATTCSTSGGVLVMEEN"
    },
    {
        "reference": "MAPNNVDNPQNCVVNNTINGGVGVDDEETYGYAAQVLNSCVLPMVLNATIELGVLHLVNQAGSGPDGLSPAQLAALIQARNPDASVMLDRMLRVLATYDVVSCTAVPTEDGGFERRYGPAPVTKCFVPDEDGVSLAPMLNLVIDKVFLQSWSKLKEAVMEGGIPFNKVHGMHAFEYPAVDPRFNEIFNKAMYDQSTHIIKNILAKYKGFSQIQQLVDVGGGLGHTLRVITSKYPSIKGINFDLPHVVEHAPQIPGVEHVGGDMFESVPKGDAIFMKWILHDWSDDKCLTLLKNCYKALPENGMVIAVETNITDQPETTAYARAISQLDVSMMTQNPGGKERTRREFESLAKSAGFARVDFVCCASSFWVMEFHK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            },
            {
                "GO-ID": "GO:0046983",
                "GO-Name": " protein dimerization activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 131,
                "End": 372
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 128,
                "End": 374
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 374
            },
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 17,
                "End": 125
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 374
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 151,
                "End": 356
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 34,
                "End": 355
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 131,
                "End": 372
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 128,
                "End": 374
            },
            {
                "InterPro-ID": "IPR012967",
                "InterPro-Name": "Plant_O-MeTrfase_dimerisation",
                "InterPro-Type": "DOMAIN",
                "Beg": 26,
                "End": 128
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 131
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MSATATMVAAARAVATRSENALINDPFAEPFVRAVGVDLFDRLADDPEGAERMGRIADGMAIRTRFFDDFFLDATAAGIRQAVILASGLDSRAYRLPWPAGTVVYEIDQPQVIEFKTTTLAGLGAQPTADRRTVAIDLRDDWPAALRKAGFDPARPTAWSAEGLLIYLPPEAQDRLFDNITALSAPGSRLATEAMPGITDAETMRKWGLDFDMSKLVYHGERNDAAAWLSGHGWDATATTVRELFARYGRPVPEDADDFGAVQLVSAVLR",
        "response#2": "MPRARARRAAPPPPPPPPPPPPPPPPPPPPQQQQQQQQQPPPPPPPPPPPPPPPPPPPPPPQQQQPPPPPPPPPPPSAHGEHDSDSALGTSTASSTTSLASSILQYRQENGRTYHAYYREGKYNFPNDEREQDRLDLLHHIFTLTLDGKLYLAPLENPQRILDVGTGTGIWAIDVADAHPSAQVIGTDLSPIQPSWVPPNCQFEVDDVEEDWTFYPFDFIHIRMMTGSIADWPRLYRQALEHLKPGGYFEQVEIDFAPRCDDGTLPEDSALAKWSNLLIEASDKFGRTLRVAPLSKGLMVEAGFVDVVETVYPIPCNWPADPRLKELGRWYNLALTEAIEALSMAPLTRAHQWTQTEIQVLLVDVRKYTKDPR",
        "response#3": "MATATNQPTAVTEEIPYGTIDPDTDSALGSSTAASSTTSLASSIMQYRFENGRTYHRYKEGKYFLPNDETEQDRLDLQHHIFTLTLDGKLYLAPIGCNPQRILDVGTGTGIWAIDVADKYPSAQVIGTDLSPIQPSIPSSVPPNCRFEVDDVEEPWTYSKPFDLIHIRMLTGSIADWPRLYRQALEHLQPGGYLEQVEIDFAPRCDDDTLPNDCALARWSNLFIEAGEKFGRTFTVVQDHSKKMLVDAGFVDVVETVFKWPLNPWPKDPHLKELGRWYNLNLTEALEALSLAPLTRAHGWTPSEIQVFLVDVRKDIKNRNIHAYNNIHVVYARKPEENEN"
    },
    {
        "reference": "MGTAPAYSLDGGRSLHRWLRDMREHHPVHRELLTRVWTLYRYRDITQATADPAVFSSELWRYLPGDRGDDALTAGNLTAMDPPRHRLVRDLVSRSFTARAVGALRPRIAAIAAELIGAVADRGEMDVVADLSDPLPVLVIGELLGLPMADRELLSDWARRLLSFDKGDLTDEVVRKRVADTQQELLDYLRVHCRRRRTNPQDDLISRLIRAEVDGQRLTEDEVVNFANLLLLAGHVTTTLLLANIVLTLDEHPAVAAEARADRGLIPGLIEETLRYRPVIVSNMRVTTRAVTVGTEQLPAGQLVSLSFISGNRDEQYFTDPDRFDIHRDARKHLGFGHGIHYCLGAPLARLELGIALDAMFDRFSRIEVTGVPVDYYDTPGVAGPRSLRIAFRHH",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 268,
                "End": 279
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 233,
                "End": 250
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 343,
                "End": 354
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 334,
                "End": 343
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 393
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 261
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 266,
                "End": 367
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 336,
                "End": 345
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 394
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 268,
                "End": 279
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 233,
                "End": 250
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 343,
                "End": 354
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 334,
                "End": 343
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 7,
                "End": 393
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 174,
                "End": 261
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 266,
                "End": 367
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 336,
                "End": 345
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 285,
                "End": 312
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 143,
                "End": 158
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 268,
                "End": 279
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 80,
                "End": 91
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 187,
                "End": 209
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 313,
                "End": 328
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 334,
                "End": 343
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 343,
                "End": 354
            },
            {
                "InterPro-ID": "IPR002397",
                "InterPro-Name": "Cyt_P450_B",
                "InterPro-Type": "FAMILY",
                "Beg": 126,
                "End": 142
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 8,
                "End": 394
            }
        ],
        "ipr_mapped": [
            18,
            19,
            21
        ],
        "response#1": "MRKKNYKDAIQWFEENAKGSETYDPALAQLSLSVAAIHTTSDLLSQTLFDLCAQPELIQPLREEIVSVIKEHGWKKTALYKLKLMDSVLKESQRLKPVAVVTMNRLVVKEGVTLSDGTFIPKGTKIAVSAYKMWDPEIYEDPLKFDGYRFVRNRNSAQLVSTSPDHLGFGHGRHACPGRFFAANEVKIAVCHILLKYDFKLPEGVERPKNINAGEFILADPSAKVMVRRRKEEIDLESE",
        "response#2": "MHQTVLRLVAQLSSRVFLGLPLCRNEKWLDITVNYTVNAFVAAEELRLWPEFLRPIVHWFLPSCRKLRTQLAEAREIITPVIEERRRQQQQQQQQQQQQQQQQPQQQQQQQQQPYNDTIQWFDENARGSTYDPAVAQLSLSVAAIHTTSDLLTQVLFDLCAQPELVQPLREEIIGVLGSGWKKTALYNLKLMDSVLKESQRLKPVNVVGMHRVATRDVTLSDGTFIPKGTKVAVAAHAMWDADIYEDPEKFDGYRFVRMREVPGQENSAQLVSTSPEHLGFGHGKHACPGRFFAANEVKIALCHILLKYDWKLAEGAKPRSINTGIFLSSDPSALVLVKRRE",
        "response#3": "MHETVLRLVAQLSSRVFVGLPLCRNEGWLKITVDYTVNVFTAAEELRIWPEILRPVVHWFLPSCRKLRKQLAEARKIINPVIEERRRAQEAAKAASKDEAGEKPEKYNDAIQWMMDNATEAERDPDLLAHRQLALSVAAIHTTSDLLTQVLFDLCARPELIQPLRDEIVSVIREHGGWKKTALYNMKLMDSVLKESQRLKPVNVVSMHRMVMKDVTLSDGTFIPKGTKVSVAAYPMGRDPDIYPDPDRFDGYRFCNPQAVSPSPEHLGFGHGRHACPGRFFAANEVKIALCHILLKYDWKLPEGTERPKNINVGDFVLADPTAKIMVKRREVEI"
    },
    {
        "reference": "MKTMLAAPTASSNGRPIGPHKSWKKVNEERKALKRQRKQDKLLKELQQAKEAESQAGKAANEVQAKDKPNPSTLSIAVPGSILENAQSNELRAYVAGQIARAACIFRVNEVIVFDDVGIATARETKRSYEADGEGSSTGTVRSSSLQLARILQYLECPQYLRKYFFPLHKDLKYSGLLNPLDTPHHLRQQSKFRYREGVICDKKAKEGHSYANVGLLNDVLVDKAIEPGVRVTVKMEPQSESCRKQRGTLVSPDEPRRETGVYWGYQVRIAHSMSEIFTKSPYATGYDVTVGTSDRGTNVHEVPNRSYNFNHMLIVFGGLQGLESALANDEKLTVDDPELLFDHYVNVLPRQGSRTIRTEEALLIALAALQEKLQPQVADVEIDLTDLLPKSEDSGIAVRRDVLVSKKQKKRKQVEDTPDETVVDEPSFSKPLPKVARLTANPFADSSEELAKNTPAQDDFEVVSSTTVSGTSHSCADDDLSRFD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within tRNA_m1G_MTases_N, NA-bd_OB-fold, Alpha/beta_knot_MTases, NA-bd_OB-fold sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity,methyltransferase activity,S-adenosyl-L-methionine binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            },
            {
                "GO-ID": "GO:1904047",
                "GO-Name": "S-adenosyl-L-methionine binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008173",
                "GO-Name": "RNA methyltransferase activity "
            },
            {
                "GO-ID": "GO:0070042",
                "GO-Name": " rRNA (uridine-N3-)-methyltransferase activity "
            },
            {
                "GO-ID": "GO:1904047",
                "GO-Name": " S-adenosyl-L-methionine binding "
            }
        ],
        "go_f_mapped": [
            20,
            20,
            99
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029026",
                "InterPro-Name": "tRNA_m1G_MTases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 74,
                "End": 368
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 186,
                "End": 254
            },
            {
                "InterPro-ID": "IPR029028",
                "InterPro-Name": "Alpha/beta_knot_MTases",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 70,
                "End": 372
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 184,
                "End": 265
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR003750",
                "InterPro-Name": "Put_MeTrfase-C9orf114-like",
                "InterPro-Type": "FAMILY",
                "Beg": 73,
                "End": 361
            },
            {
                "InterPro-ID": "IPR003750",
                "InterPro-Name": "Put_MeTrfase-C9orf114-like",
                "InterPro-Type": "FAMILY",
                "Beg": 73,
                "End": 370
            },
            {
                "InterPro-ID": "IPR029026",
                "InterPro-Name": "tRNA_m1G_MTases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 74,
                "End": 368
            },
            {
                "InterPro-ID": "IPR003750",
                "InterPro-Name": "Put_MeTrfase-C9orf114-like",
                "InterPro-Type": "FAMILY",
                "Beg": 21,
                "End": 375
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 186,
                "End": 254
            },
            {
                "InterPro-ID": "IPR029028",
                "InterPro-Name": "Alpha/beta_knot_MTases",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 70,
                "End": 372
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 184,
                "End": 265
            }
        ],
        "ipr_mapped": [
            968,
            970,
            204
        ],
        "response#1": "MTRTPTPTLLPPRRRLPARLRTQPARPPPAQPAARPPAQPRPRTQPARPAPAQPAAQPPAPPRTQPAARPPAQPAAQRPPRPPPRPPPRHRPRPQRPARRPQPRPPGRPLHRPAAQPRRRPPPRRPPPPQRPRRPRHRRPTRRRPPRRRRHRPPPRPRPHRPRHPRRPPPRMTADVRTVAVDLRQDWPDALRAAGFDPARPTAWSVEGLLVYLPPADAQTRLLDRITALSAPGSQLAVNDVNPAARTGSDTGWRHRPGGAWTWYADRRTDAAAWLRDRGWTVDTRPAEELLRAAGRTPEGAPTEPPATTLLTATRA",
        "response#2": "MTTAPRPYEQAVLDHLPPGSTVLDLGCGTGFLADHLRRHRPDLRLVGVDIDPDAVARTRERLADPRTEVRVADVRTADLPPADVVLASEVLYYLSPDDQDRLLTRLADALRPGGRLVLDDPDPDAAAPAPAPRTPRPPRPAAPGSRPDPRPAAPAPRPHRPRRPARRERRRPAELADRLTRHGFTVTPLTEADARRLGYPPDPGRPPRRTLLLAERREETR",
        "response#3": "SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSKSSSSSSSSSSSSSAAAAAAAAAAAAAAAAAAQPRQPQQQQVRPQQPRPPPQQQQQQPRRQQQQRQQQQPQRPPRPRQQPPPRQPQRQPQQQRQQQQPQQRPRPRRPPPTPQPQPPQRRQPRQPRPRPQQRQPQRQQRPHQRQRPRQQPRPQPRPQQQQPRQQPQHRQQPRRRPPPQQQPHRHRQPRPPPPQRQPQRQQPRPQPQRRPPRQPPRRPRPPPPPRPRQQRPPRPPRPPRPRQPPRPRRQQRPHPRRGPRPRPRQQQRPPPPRRQQQQPQPRPRQQQRPQQRQQRRQQQRPRRQRRQRQLLQPGRQQQHQQ"
    },
    {
        "reference": "MTNRLELSGIICRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGHENQAITHSITVGSAVTVRGFISCHKAKNGLSKMVLHAEQIELIDSGD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Primosome_PriB/ssb that shares evolutionary origin and functional similarity; 2. The protein should be classified within NA-bd_OB-fold, NA-bd_OB-fold sharing conserved structural features; 3. The protein must be able to perform the single-stranded DNA binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003697",
                "GO-Name": "single-stranded DNA binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003697",
                "GO-Name": "single-stranded DNA binding "
            }
        ],
        "go_f_mapped": [
            83
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 104
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 103
            },
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 101
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 104
            },
            {
                "InterPro-ID": "IPR023646",
                "InterPro-Name": "Prisomal_replication_PriB",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 99
            },
            {
                "InterPro-ID": "IPR023646",
                "InterPro-Name": "Prisomal_replication_PriB",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 101
            },
            {
                "InterPro-ID": "IPR023646",
                "InterPro-Name": "Prisomal_replication_PriB",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 95
            },
            {
                "InterPro-ID": "IPR012340",
                "InterPro-Name": "NA-bd_OB-fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 103
            },
            {
                "InterPro-ID": "IPR023646",
                "InterPro-Name": "Prisomal_replication_PriB",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 100
            },
            {
                "InterPro-ID": "IPR000424",
                "InterPro-Name": "Primosome_PriB/ssb",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 101
            }
        ],
        "ipr_mapped": [
            732,
            204
        ],
        "response#1": "MSINRVVLVGRLTKDPELRYTPSQVAVATFTLAVNRTFKNQQTGEREADFINCVIWRQQAENVANYLKKGSLAGVDGRIQTRNYDNQQGQRVYVTEVVAESVQFLESRATREGGNSQNNFNQNNQNQNQNFNQNNNFNQNQNNFQQNQNQNFNQNQNQNNFNQNQNFNQNNFNQNQNMNQNNQNQNFNQNQNFNQNQNQNNNFQQNQNNMNQNQNFNQNQNFNQNQNQNFNQNQNNFNQNNNQQGMARGINRVVLVGRLTRDPELRYTPSQVAVASFTLAVNRTFNQNGEREADFINCVIWRQQAENLANWAKKGALIGVDGRIQTRNYENQQGQRVYVTEVVADSFQMLESRATREGGSSNNSFNNNDNPFGNSNPMDISDDDLPF",
        "response#2": "MARGVNKVILVGNLGQDPEVRYMPSGGAVANLTLATSESWTGQQGQRQEKTEWHRVVLFGKLAEIAGEYLRKGSQVYIEGSLQTRKWQDQSGQDRYTTEVVVNVGGTMQMLGGRGGGGGGGGFGGGGGFDSGGGGQQGGGGGGGYQQAPQQQAPQQQPQQQQQAPQGGGGWGGAPQQQQPQQQQAPQQQPQRQAPQQQPQQQAPQQQQAAPAAAPKADDDPWGASNSAPMDISDDDIPF",
        "response#3": "MAGETTITVVGNLTADPELRFTPSGAAVANFTVASTPRIFDRQSGEWKDGEALFLRCNVWREAAENVAESLTRGARVIATGRLKQRSFETRDGERRTVVEVEVDEVGPSLRYATAKVNKASRSGGGGTYGGGGGFGAPQQQQQQQQQAPAADPWGAPQQQQQQAPAADPWGAPQQQQQQQQQQAPAADPWGAPQQQQAPAADPWGAPQQQQQQAPAADPWGAPQQQQQQQQAPAADPWGAPQQQQQQQQQAPAADPWGAPQQQQAPAADPWGAPQQQQPSFDDEPPF"
    },
    {
        "reference": "MSTYGTLLKVTSFGESHGKAIGCVIDGFLPNVEINFDLIQRQLNRRRPNQSKLTSNRNEPDKLIVLSGFDENKTLGTPITFLINNEDVIKKNYSSFIDIPRPGHGDYTYFKKYNVKNKSGSSRFSGRETATRVAAGACIEQWLHTFYNCTIVCYVHSVGNIKLPEQVSKDFERNPPSRDLVDAHGAVKYHQGRGTFTDFFGNVYNANGEFLRGGEAAPEGATPADGTPTDGNPTDDPLANARERLSDPGECTLLQTRCPHPLTAVKICSYILKLKKAGDSIGGVATCIAHNVPVGIGEPIFEKMEAELGKIILSIPAVKGIEFGSGFDGTYMLGSDHNDLFGTLDVPEEGPCQRGWTLTDALDSKRGEVTPGGSRAQEGTSFEKDACHRSGHLSNLSGYPSNGSGNPPNGSDHPSNRSGNPPNRSDPRVDESTRETSPPSGEKLLVTTSNNCGGILAGITTGNNIVFRSAIKPVSSIQIEKETCNFFGEKCKLKVTGMHDCCILPRLPPIIEASTSIVIGDMILRQVAKYGHSKLPSVGSLSRSTRE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Chorismate_synth, Chorismate_synth, Chorismate_synth, Chorismate_synth, Chorismate_synth that shares evolutionary origin and functional similarity; 2. The protein should be classified within Chorismate_synth_AroC_sf, Chorismate_synth_AroC_sf, Chorismate_synth_AroC_sf sharing conserved structural features; 3. The protein must be able to perform the chorismate synthase activity,FMN binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004107",
                "GO-Name": "chorismate synthase activity"
            },
            {
                "GO-ID": "GO:0010181",
                "GO-Name": "FMN binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004107",
                "GO-Name": "chorismate synthase activity "
            },
            {
                "GO-ID": "GO:0010181",
                "GO-Name": " FMN binding "
            }
        ],
        "go_f_mapped": [
            58,
            59
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 531
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 535
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 522
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 534
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 427,
                "End": 536
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 445,
                "End": 524
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 342
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 375
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 531
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 535
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 522
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 4,
                "End": 534
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 427,
                "End": 536
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 445,
                "End": 524
            },
            {
                "InterPro-ID": "IPR000453",
                "InterPro-Name": "Chorismate_synth",
                "InterPro-Type": "FAMILY",
                "Beg": 8,
                "End": 342
            },
            {
                "InterPro-ID": "IPR035904",
                "InterPro-Name": "Chorismate_synth_AroC_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 375
            }
        ],
        "ipr_mapped": [
            142,
            143
        ],
        "response#1": "MESNPFFCPDPAVVPLFEEYLDALRKDGDSIGAVVEVVARGVPPGLGEPVFDRLDADLAKALMSINAVKGVEIGAGFAAARLRGSENADEMRLGADGRPVFLSNHAGGILGGISTGQDVVVRFAVKPTSSILTPRRSIDRAGNAVEVVTKGRHDPCVGIRAVPIGEAMMALVLMDHFLRQRAQCGDVRVETPRVPAAAAPSEAETADEPVK",
        "response#2": "MSEGCRLDGARLKKKRKGPVIGRRARPLGGICKSQGRQCQGCHRHFAPRPFPSIRGNEAGRLKGIFEVSLILISPTAQLLKNVDSNPVRCLDEEAGKLMMEKIDAAKKDGDTIGGIVEVVVEGVPVGLGSYVQWDRKLDAKLAAAVVSINAFKGVEIGLGFEAARKKGSQVMDEILWNKEEKGYTRRTNNAGGFEGGMTTGQPLVVRGVMKPISTLYKPLMSVDIETKEPFKATVERSDSCALPAAGVIAEAMVAWVLADAFLEKFGGDSLEELKRNVEEHRRLTREY",
        "response#3": "MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQIGDIKLEIENASFFVDKDKAEALKELMDALRKEGDSIGAKVTVVASGVPVGLGEPVFDRLDADLAKALMSINAVKGVEIGDGFDVVALRGSENRDEIRMGTQGQPVFLSNHAGGILGGISSGQHVVAHFAVKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIGEAMLALVLMDHLLRQRAQCR"
    },
    {
        "reference": "MPPVSRILSYAPRVAIRPSSQLARPARAFAVGTVRYYSAEQPEEPLIRVTDLPAPNSGHIRVLELNRPKARNAISRALLASLREEVHSIARQYDAQTGEEIPTPSWNKRFGGIAGDSEKGPTRALVLASAVESSFCAGADLKERRGFTQEETNEFLANLRSTFAALDALPIPTISAISSRALGGGLELALCTHFRVLTSNAIVSLPETRLGIIPGAGGTHRLPRLIGLGRARDMIVTGRAVSGAEAYFLGLADRLVEVLPPDEQEAADTTDKDAALLSAAREAALTEAVRLASQICEGGPIGIRAALQAVQAPSQETENKMYERVIGTEDRNEALKAFAEKRKPVFKGR",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within ClpP/crotonase-like_dom_sf sharing conserved structural features; 2. The protein must be able to perform the lyase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016829",
                "GO-Name": "lyase activity "
            }
        ],
        "go_f_mapped": [
            32
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029045",
                "InterPro-Name": "ClpP/crotonase-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 57,
                "End": 349
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR014748",
                "InterPro-Name": "Enoyl-CoA_hydra_C",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 292,
                "End": 349
            },
            {
                "InterPro-ID": "IPR001753",
                "InterPro-Name": "Enoyl-CoA_hydra/iso",
                "InterPro-Type": "FAMILY",
                "Beg": 122,
                "End": 348
            },
            {
                "InterPro-ID": "IPR029045",
                "InterPro-Name": "ClpP/crotonase-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 57,
                "End": 349
            }
        ],
        "ipr_mapped": [
            235
        ],
        "response#1": "MPRDDAPRRDGAPRRDGAPRRDGTDRRDGAPRRDGAPRREDAPRRDGTPRREDAAPREGAPRREDARPPRDRDRRPDRERDRRPEDRRDRRDDRDLRPEAPRGRPDGRRDGPPDRRPEAPRGRPGPGPERPDGRPGDGRPRRDDGRPRRDDPRRDGPPAPRPERPPAPRPDRPPAPRPERRPAPPERVDAVVVAPGPDAAAAVAAAARAGLPVVLVPPWAAPAAAARLAGDAVSGGALRPVVVAVRPGAVAAAAAVAAAAAAAAAVAAVPREDEDEAVAPAAVRAARADVAVAVPAEEDGPPRPAPRAAAPPVPAPRGAAPPVPAVRTAAPPVPAVRTAAAPTPAARPPAPAPAPVPRAPR",
        "response#2": "MAVRVIPCLDVDGGRVVRGVKGVNLVALRDAGDPVEIAKRYDEQGADELTFLDITASADGRDTILDVVARTAEQVFIPLTVGGGVRTIDDVRRLLLAGADKVSLNTAAVARPELVAEAAARFGSQCIVVAVDARRGRSATGLDAVEWARRVEELGAGEILLTSMDADGTKSGYDLELTRRVCEAVSVPVIASGGVGTLQHLADGVAAGASAVLAASIFHFGEITP",
        "response#3": "MPPLDRPPRPDCRPGVRPTGQPVTRPPVTRPPVPDRVTDRPHPGRSRAARPPGARPVGNRPAAAVRPVDLPALVRPAGRPAPGRGAPLVADRPRDADRPADRGPAGPVPPAADRTVRLRPADAPRGAAPRAVARSPDAPAAAGARPVPDPAVDRAAHRAAPVPLADRDARPVPGRRPDGRVAAAGTAGVPPEARARADALAAPVRRAAALDGRALVDHRRPDRPGARRAAPDGQPPAPRAGGALGRRPDRPRAPRPAPARDVDGAHRGERPEGPRPAGRPAAAEPPVAGTDRTGRVAARHRRAAAVVPVHADRPDRRRAAVPDVPAAPDPRAGRRAIRAGAAGTGRRAVPDRRAEPDREPPPGRGAARP"
    },
    {
        "reference": "MDLLQRAGLVVGLWVTYHILLGTYNVFFHPLRRFPGPRLAAATQLVNVYYIIRGINCKYLYELHEKYGDVVRTGPNELSFRTASAIRTIYGGNPGPDDTFHKNMIANIQETGDSDNLFFATGQQHNRYRRLIMPVFAERTIQGQGPMMQEYCSQLIQGLRNRCGRGYFPTQDGVVDIVPWTHFIISDILSHMLFGSGMNCLLNGDYHPWVMAGYKALIESTYIEAAHRLRPYHRILEYLLIPTRLRDGFRVHSAVSREKLQARSKEAEPYQFSLPSFTSESLSEQELFDNINVIATAAGETTSSALSAIMYYLTANPAAYDKAVTEVRQAFSNEAEITAASSASLPYLKAVIREAFRIRPTIPVGLHRLTPKGGREIDGKWVPAGTWISVANLAACRTSSHWKEAGRFIPERWLGDPEFASDNRDTSVPYSIGVRNCIGMSHANTQLRLILSRLLWNFDFEACPGNADPYDYLEYGTWQVEPLKLRVVDIRGQPK",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cytochrome_P450_monoxygenase that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 492
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 53,
                "End": 469
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 488
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 303
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 349,
                "End": 367
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 306,
                "End": 332
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 437,
                "End": 460
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 391,
                "End": 415
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 427,
                "End": 437
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 350,
                "End": 361
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 428,
                "End": 437
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 437,
                "End": 448
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 297,
                "End": 314
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 461
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 26,
                "End": 492
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 53,
                "End": 469
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 34,
                "End": 488
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 286,
                "End": 303
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 349,
                "End": 367
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 306,
                "End": 332
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 437,
                "End": 460
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 391,
                "End": 415
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 427,
                "End": 437
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 350,
                "End": 361
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 428,
                "End": 437
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 437,
                "End": 448
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 297,
                "End": 314
            },
            {
                "InterPro-ID": "IPR050121",
                "InterPro-Name": "Cytochrome_P450_monoxygenase",
                "InterPro-Type": "FAMILY",
                "Beg": 10,
                "End": 461
            }
        ],
        "ipr_mapped": [
            18,
            20,
            21,
            31
        ],
        "response#1": "MVKWFNFTTFDIIGDLTFGEPFGCLDKSEYHPWVAAIFDSMKMGAAIHVANQYPWLEKAVLWFFPQSLKQKRAKHLSLSREKVDARIAAKKAAEAGGTSTKGEKDRPDFISAILRHNDSAKGLTLDEIHANASLLIIAGSETTATLLSGVTYLLLKNRRAMEKVTEEVRSTFREDEITMLSVNHLRYLQAVLEEGLRLYPPVPAGLPRVVPEGATIDGQWVPGNTVVSVSQWAAYHSEANFKDPESFIPERWLDDHPEFKNDKRDALQPFSIGPRNCIGKNLAYHEMRLILARMLWYFDLELCEESRDWLQNQKVYLLWDKPPLMVRLTPVKRSEACTV",
        "response#2": "MVDATVAAVVALRASPSFLRPLVHWFLPCTRLRKQHAEARKMIKPVIEERLRTKEAKGEAYEKPNDMLQWMMDHATPAERNPDLLAHRQLALAIAAIHTTSMSMTHAIFDLCARPEYVQPLREEIVGALRESKGELTKAALYKLKKMDSFMKESQRLNPPVVVSMHRYAMEDVTLSDGTFIPKGTRVSVPAYAMGRDEAIYKDPLSFDGFRFCGERAKHQYVSTSPNHLHFGHGKHACPGRFFAANEIKIALCHILLKYDFKLENERPKNVNMGSFILADPTARIMVR",
        "response#3": "MAQAFHAARKGESMLRHFPWLRPLLVRLIPERSIQLRQEHMALTKQKVDERLAFKTDRPDFMSAMLRNKDSEAGMTHEELHANASLLIIAGTETTATALSAVTYFLLRNPDAMQRATEEVRSTFKSEEEIKAGASINHLKYLQAVIEEGLRMYPPVPANLPRVTPEGAVIDGQFVPGGTVVSVSQYASYSPRNFHNPDSFHPERWLDPSHPHYDEKFANDKRDALQPFSLGPRNCIGKNLAYHEMRLILARLLWNFDLELCEESKDWVDQKTYLLWDKPPLMVRLTPVQRKA"
    },
    {
        "reference": "MAPSAEGASGAPTPEDLKLHQLSQKYTAEAAKRFRPEGLGQFIRLKEVGNERFRALAEDPWVDHAALNAKEPVKDGSRYKFIILGAGYGGLLYAVRLAEAGLASGPDDILMVDAAGGFGGTWWWNRYPGLHCDVESYSYMPLLEETGYIPKSKYAAGPELLEHAYRIATQWKLHDKALFRSNVKTIRWDDESRLWSLEVTEGRGPGQQSRELKLQARYVLLASGILTNPQVPKIPGLETFTGPVFHTARWNYDVTGGSPTDEALNRLEGKRVGIIGTGATAIQVVPKLAKYAKELYVFQRTPSGVWWRGQRPTDPVEWKTKIARKKGWQRERMLNLDSYLTDAAEEGQENMVADGWTEMPAFSAVIGSPRHGIVEPTPEKIAEHLGRLYKLDLPHAEQVRARTDSIVKDPKTAAKLKAWYPTWCKRPTFSDEYLQTFNLPNVHLVDTDGKGVDAANPSGLVVADKEYPLDILVLSTGYVTPSIGGGSPAVRTGVDIYGRGGKSLDDKWQTHGAATLHGVCSNGFPNLFFTPLSQSSQAANNAFTLDVGTEHIVQVIKTAEDRVDGDALVEVTSEAEEAWSFEIMKHAGWFASVTGCTPGYITSEGEALRKSEDPMEMAKRARSGNLSQGMASYMKLLQEYRADGSLKGFDISSRA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more FAD/NAD-binding_dom that are essential for its biological function; 2. The protein should be classified within FAD/NAD-bd_sf, FAD/NAD-bd_sf, FAD/NAD-bd_sf, FAD/NAD-bd_sf sharing conserved structural features; 3. The protein must be able to perform the nucleotide binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding "
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": " oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            61,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 229,
                "End": 478
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 76,
                "End": 361
            },
            {
                "InterPro-ID": "IPR023753",
                "InterPro-Name": "FAD/NAD-binding_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 79,
                "End": 302
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 78,
                "End": 319
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 446,
                "End": 652
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 229,
                "End": 478
            },
            {
                "InterPro-ID": "IPR050775",
                "InterPro-Name": "FAD-binding_Monooxygenases",
                "InterPro-Type": "FAMILY",
                "Beg": 56,
                "End": 653
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 76,
                "End": 361
            },
            {
                "InterPro-ID": "IPR023753",
                "InterPro-Name": "FAD/NAD-binding_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 79,
                "End": 302
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 78,
                "End": 319
            },
            {
                "InterPro-ID": "IPR036188",
                "InterPro-Name": "FAD/NAD-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 446,
                "End": 652
            }
        ],
        "ipr_mapped": [
            402,
            43
        ],
        "response#1": "MPSFDTVSEVDLQKVKEASERSSKELKTRFKIDARIEQKDKEITVFSEDEFKLKQVQDILRTQLAKFDLDARFLDFNYKSVKYKGDLDKVVKTVKETLKINSELDIKTEKGKGYQQVTKVKDGISKETVEKVKELLKKEKLKVQLEIKEDELHMYSKSEFELGQAQALLKKNLKDLKLDAKLEDNFQVVEGINIDVVKETVQRLSKDLKDKKIDARLEQKDKELTLYSKSEFDLQQAIGLIKSELIKLKLDAKFLDYKEVEKIGGDSYKQVVELKEGIDKELAKEIVKLVKDSKLKVQAQIQGDAVRITGDKFDDLQSTIALVNKLKNK",
        "response#2": "MPARLELRLEGPLPREALERALEAARRRLRRELRLPEGARARLEGEALVLEAEDEAALEALLEALRREARRLGLRWEDELEAALERAPDGRRRLRLRLPPPPPPPRPPRRELELRAELEGPLPPEALERLRRRLEREAPPGLEAELEGRALRLRAPSLEAARRLAARVRRLLEELGLRGALELEVEREEPPRWRLRLRLRAPLPPEALERLERALREALPEARLRREGEALLLEAPSLAALLEAQARARELARELGLPLELRAEPPRPPPPPPPPPRPRRP",
        "response#3": "PPRRRPPQAPAPPRPPRLEARLEAPEPERARRALEEAREALEEALREEGLEARLEWRLEEGRLEARAPSPEALERAREALLRALARLGLPPEALELEARREGEALRATLRAEGEEALEALEGALEEALAPLGLEAEVEVRREGEAFALRLRPRRPLEEALERAERRAREALAREGLEARLERRGEALLLRAPSPEALERARRALERELARAGVPAEALREERLEREGEGRVRRALRLERGLRGEEAERLREALRERLPPEAQVQLQGEALRVTAPSFEALQRAQALARELWPEAPLDFR"
    },
    {
        "reference": "MYYRETMLAFVPYLAVFVACYGLVYYRRKRQRLPLPPGPPQLPLVGNLYQIPEMNPWRTYREWHQKYGPIITVKSGLTNTIILGSHKAARDLLDKRNRNYGSRPHFILIGDFIYGGNQTSLLPTGQRWRIHRRILSAFGNVRTSQRYRILYDAESKRLLREILHGGDFFEPFHHYFVRILFALTYGKRVTGSHDPEARDVIEIVDVVLKEASRSSVPEAFPILNSLPGALAPWKRRAQLLFEQHSRLFDNHMNAALANKPWNFCKQALRLKASSEVDRVELNFILGSITEATHSGSMVLGVFIMANILHPDAVRWVQEEIDRVIGPDRLPSFDDMAKLPYLNAYLLEVMRWRPITPGGMPHASFQDDEYMGYHIPKGTTVVANHWSMDFDESVFTDPYEFRPQRWIEDPNLPSIAFGFGTRICPGRHIAESSIFIVAARLLWSFNFDYAYEDGKRQEIDSWNMTQGLDSGPMPFKASFKIRSPKHQEVMDRECGVSDLDIDAILDKIGADFL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450_E_grp-I, Cyt_P450 that shares evolutionary origin and functional similarity; 2. The protein should be classified within Cyt_P450_sf, Cyt_P450_sf sharing conserved structural features; 3. The protein should contain Cyt_P450_CS that is preserved across related proteins; 4. The protein must be able to perform the heme binding,iron ion binding,monooxygenase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding"
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": "iron ion binding"
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": "monooxygenase activity"
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0020037",
                "GO-Name": "heme binding "
            },
            {
                "GO-ID": "GO:0005506",
                "GO-Name": " iron ion binding "
            },
            {
                "GO-ID": "GO:0004497",
                "GO-Name": " monooxygenase activity "
            },
            {
                "GO-ID": "GO:0016705",
                "GO-Name": " oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen "
            }
        ],
        "go_f_mapped": [
            12,
            13,
            14,
            15
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 308,
                "End": 321
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 414,
                "End": 423
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 423,
                "End": 434
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 343,
                "End": 354
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 413,
                "End": 423
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 88,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 383,
                "End": 407
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 342,
                "End": 360
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 299,
                "End": 325
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 83
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 423,
                "End": 446
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 496
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 36,
                "End": 481
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 416,
                "End": 425
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 456
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 308,
                "End": 321
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 414,
                "End": 423
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 423,
                "End": 434
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 343,
                "End": 354
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 413,
                "End": 423
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 88,
                "End": 109
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 383,
                "End": 407
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 342,
                "End": 360
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 299,
                "End": 325
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 64,
                "End": 83
            },
            {
                "InterPro-ID": "IPR002401",
                "InterPro-Name": "Cyt_P450_E_grp-I",
                "InterPro-Type": "FAMILY",
                "Beg": 423,
                "End": 446
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 27,
                "End": 496
            },
            {
                "InterPro-ID": "IPR036396",
                "InterPro-Name": "Cyt_P450_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 36,
                "End": 481
            },
            {
                "InterPro-ID": "IPR050364",
                "InterPro-Name": "Cytochrome_P450_fung",
                "InterPro-Type": "FAMILY",
                "Beg": 13,
                "End": 494
            },
            {
                "InterPro-ID": "IPR017972",
                "InterPro-Name": "Cyt_P450_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 416,
                "End": 425
            },
            {
                "InterPro-ID": "IPR001128",
                "InterPro-Name": "Cyt_P450",
                "InterPro-Type": "FAMILY",
                "Beg": 36,
                "End": 456
            }
        ],
        "ipr_mapped": [
            18,
            19,
            20,
            21
        ],
        "response#1": "MGEELEKAGREVDAFFTEVIEEHKNLKLNNGKRKDLVDVLLELQEEEGQDFTLNMDNIKAIILDMFVAGTDTSASTMEWAMSELIRNPRVMEKAQAEVRNVVKAKKDEGKEEEEKGKVEESDLKEMVYLQAVVKETLRLHPPAPLLLPREANPDETIYKDPLEFKPERFLSNDGSVDVKGRDFELIPFGAGRRMCPGMPLAYRTLHLALAQLLYHFDWKLPNGMKPEDVDMDEKFGLTLQKANPLMAVPIPRLPRP",
        "response#2": "DIQGFKKKAAKARKEMDEIFERVIEEHKQLRVKGTPKDLVDVLLELQEDPNLKFQLNSDNIKAIILDMFVAGTDTSSSTVEWAMAELMRNPRVMEKAQAEVRNVIGDSKREVKESDISNLPYLQAVVKETLRLHPPVPLLIPRESREDVEVSGYLIPKGTKVLVNAWAIGRDPKYWENPLEFKPERFETSVDVKGKNFELIPFGAGRRICPGLPMALNVVNLALAQLLYHFDWKLPEGMKPEDLDMTEKPGLTILS",
        "response#3": "FPILKFLDLQGTRKRLAKAFGKFDKIFEERLEEHRTSFTAGSKRDLIDVLLSIMDSNSTLTMDNIKAMILDLFIAGTDTSSSTMEWAMTELLRNPRVMEKAREEVRSVVGKERGRVEEADINKLPYLQAVVKETLRLHPPAPLLIPRESREDCKVSGYDIPKGTKVLVNAWAIGRDPKYWTDAESFKPERFLNSSVDVKGKNFELIPFGAGRRICPGLPLGLATVELALAQLLYSFDWKLEGEKPEDVDMTEKFGLTVKKAVPLRVIPIKV"
    },
    {
        "reference": "MDNSSRLFSPLRLGKCQLRHRVAMSPLTRFRADDLSVQMPFAKEYYAQRASVPGTFLVSEATSISRESVGFSNVPGIWNAEQVRAWKEIADDVHCKGSFLFLQLWATGRSATPERLQSGDFDFASSSAVPMEPGGAVPRELTEEDIHDLIARFAEAARRAIDAGMDGIELHAANGYLIDQFTQASCNQRTDRWGGSIENRARFAIEVTRSVVAAVGADRVGVKLSPWGKIQGMGTMQDLVPQFQYLVSELRDMGLAYLRLSNSRWIDGVPQEEEDNSIYVHTWGASRPVLLEGGYDPISAQKEADIRFNGYDAVIAFGRFFISNPDLPFRIKAGVDLQKYNRDTFYTPISEKGYIDYPFSTAFLEEHSSKASLKL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Aldolase_TIM sharing conserved structural features; 2. The protein must be able to perform the FMN binding,oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0010181",
                "GO-Name": "FMN binding"
            },
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0010181",
                "GO-Name": "FMN binding "
            },
            {
                "GO-ID": "GO:0003959",
                "GO-Name": " NADPH dehydrogenase activity "
            }
        ],
        "go_f_mapped": [
            59,
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 370
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR001155",
                "InterPro-Name": "OxRdtase_FMN_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 7,
                "End": 337
            },
            {
                "InterPro-ID": "IPR045247",
                "InterPro-Name": "Oye-like",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 360
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1,
                "End": 370
            }
        ],
        "ipr_mapped": [
            101
        ],
        "response#1": "MTELTVPARALARAARAVSPRDTRPVLTGVHLTAADDRLTVTATDYERTATVTVPADSAQVRRTGDLVVPARFLADLCRAAGDADDTCTLTLTDDRLTVAVGRTRGTLRCLPADEFPAPPTAPTVTVPATALAAALARTRRAASTDDVRPVLTGIRITAADGTLTTTATDSYRLTTDTVPTDAQVPLTAIVPRRAVDDLERIVPADDTVTLRLDDTRHLLTATGDGWTLTSRLIDGDYPDTDRIVPTTPAPLTATADPAALRRALDRAAVLADRTPVRLRYADGTLTVSAHGDHGDVTEPLVDGPDGTTTVAFNARFLADALDDLGTVTLRTEPHRPLLAEGDGYRQVLMPVRL",
        "response#2": "MTDTTQLRDIADLRKDYTKGGLREKDLAQDPLAQFGRWLDEAVAAELPEPNAMTLATATADGRPSARMVLLKGYDERGFVFYTNYESRKGRELEANPHAALLFYWVPLERQVRVEGRVEKVSAEESDAYFASRPRGSQIGAWASRQSSVIESRAVLEAKVAELEEKYKDGEVPRPPHWGGYRLVPETMEFWQGRSSRLHDRLRYRRVTQAEAAGKAASASGDHWQLERVAVDEHRADAAAEAAEKAAR",
        "response#3": "MAAAPAPAHRSLLPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAAAAEGRRRRPRRRRRRRPPPRPPPPRRRRRRGRRRLRRRAPAAAAAAAAAAAAAAAAAAVAAAAGAAAGAPPPLPPEAAAAATAAAPSTRPPSGGGGGGGGERPPPRRRPRRPPPPPRRPPPPPARRRRRPPPRRRRGGGRGVGGRGGGGGGGAAAAGGRHRRRWGGGGGRRRRRRPPRRRRRGRRRGRGGGGGGGGGGGGGGGGGAAAAAAAAAAGGGGGGGGGGGAAAAGGGGGGAAAAVVVVAAAAAVVVVVV"
    },
    {
        "reference": "MNPPPSLLDKAAIVTGGSRGIGAAIAIELARRGAHVLITYNTASHKAQLVAEEIQKLGRKATVVQASSTDREGPNRIVQAAVSQYGRIDIIVNNAGMADDCLLQDLTHEFWDRIMDVNLRLPAFLVQAALQHLGPAPRIVNISSLAARAGYNATSVYAASKAALEGMTRAWATELGHRYNVTVNCVNPGPVDTDIMAVDENTDAEVVAYWNAKVKETPAAPRVGTPGDIAQIVAFLCEEGSRWCTGSVVNANGGLVTV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam, SDR_fam that shares evolutionary origin and functional similarity; 2. The protein should be classified within NAD(P)-bd_dom_sf sharing conserved structural features; 3. The protein should contain Sc_DH/Rdtase_CS that is preserved across related proteins; 4. The protein must be able to perform the oxidoreductase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016491",
                "GO-Name": "oxidoreductase activity "
            }
        ],
        "go_f_mapped": [
            4
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 131,
                "End": 147
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 179,
                "End": 196
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 219,
                "End": 239
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 86,
                "End": 97
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 157,
                "End": 176
            },
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 144,
                "End": 172
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 256
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 137,
                "End": 145
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 255
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 131,
                "End": 147
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 11,
                "End": 28
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 179,
                "End": 196
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 219,
                "End": 239
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 86,
                "End": 97
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 157,
                "End": 176
            },
            {
                "InterPro-ID": "IPR020904",
                "InterPro-Name": "Sc_DH/Rdtase_CS",
                "InterPro-Type": "CONSERVED_SITE",
                "Beg": 144,
                "End": 172
            },
            {
                "InterPro-ID": "IPR036291",
                "InterPro-Name": "NAD(P)-bd_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 256
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 137,
                "End": 145
            },
            {
                "InterPro-ID": "IPR002347",
                "InterPro-Name": "SDR_fam",
                "InterPro-Type": "FAMILY",
                "Beg": 19,
                "End": 255
            }
        ],
        "ipr_mapped": [
            8,
            9,
            7
        ],
        "response#1": "MSSTTQTQVLDKFRLDKKVAIVTGGASGIGRAAALLFAEAGAKVVIADVLEDQGKATVEEIKKSGGEAIFVRTDVSKESEVESMVNKAVEKFGRLDVAFNNAGINLRASVHETSVDDWDKVIAVNLRGVFLCMKHELKVMLKQKSGSIINASSVAGLIGGKNRPAYVASKHGVVGLTKSAALDYAKDNIRINAIAPGSIDTPMVAGILAAAEDKEAAQKLADSRHPIGRAGRPEEVAAAALFLASDASSFVTGVVLPVDGGMTASVYTPDPHT",
        "response#2": "MSKVALITGGASGIGKATAELFSKEGFKVAIADLNEEEGKKVAESINGIFVKVDVSNEKDVESFVEKTVEHFGKLDVAFNNAGVDMVKPVHETTVEDWDKVMNVNLRGVFLCMKHEIKQMLKNGKGSIINASSVAGLVGGAGMSAYTASKHGVIGLTKAAAEDYRKDGIRINSICPGGVDTPLVPGSLKPEDIAKVALFLASDESANINGQAINVDA",
        "response#3": "MASASRRLDGKVALITGSSSGIGAAAAKLFASQGAKVVVNYHSSEDAAKKVVDEIKSAGSGEAIAIKADVSQEDQVKEMMAKTVEKFGRLDFAFNNAGIGLDAKAPLHETTVEQWDKMLAVNLRGVALCMKHEIPHMLAQGRGSIVNASSIAGEIGQVGGNPAYTASKHGVVGLTKAAALDYASKGIRVNAIAPGPIDTPLNKDIYSPEFLERVASRVPLGLDAKAPLHETTVEQWDKMLAVNLRGVALCMKHEIPHMLAQGRGSIVNASSIAGEIGQVGNPAYTASKHGVVGLTKAAALDYASKGIRVNAIAPGPIDTPLNKDIYSPEFLERVASRVPLGRDGKPEEIAKAVLFLASDESSYVTGAVLPVDGGFTCY"
    },
    {
        "reference": "MCGVLALILANQSSSAANDLHEALYVLQHRGQDAAGIATSTSSGHIHIRKKNGMAADVFQSGARLANLFGSMGIAHLRYPTAGGSANTEAQPFYVNSPYGICFAHNGNLINTVELRRYLDFEIHRHINSDSDSELMLNIFADELSETKKARVNTEDIFNGLSKMYQRCEGAWACTAMLAGFGVIGFRDAYGIRPLVMGSRPSSDGDGLDYMIASESIALDRLGFTNVRDIQPGEAVIVAKGAEPVFCQVAPRKSYTPDLFEYVYFARPDSVIDGISVYQSRQRMGRYLAARLLEVLGPEGIKEIDVVIPVPETSSPAAASVAHALNKPYCAGYIRNPYVFRTFIMPGQATRQKGVRRKLSAVKEEFKNRTILLVDDSIARGTTSREAISMAREAGVKKIIAACCSPEITYPHIYGIDLPSPHEMVAYERDNNDIAQNLGADRIVYQTLEDLQASCAEIARENDFQEPHTFENGVFSGQYVTPVPEGYFALLEKIRGTGRKEALDKSSKRL",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more PRibTrfase_dom, PRibTrfase_dom, GATase_2_dom that are essential for its biological function; 2. The protein should be classified within PRTase-like, Ntn_hydrolases_N, PRTase-like, Ntn_hydrolases_N sharing conserved structural features; 3. The protein must be able to perform the pentosyltransferase activity,cation binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016763",
                "GO-Name": "pentosyltransferase activity"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004044",
                "GO-Name": "amidophosphoribosyltransferase activity "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            }
        ],
        "go_f_mapped": [
            84,
            183
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029057",
                "InterPro-Name": "PRTase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 259,
                "End": 488
            },
            {
                "InterPro-ID": "IPR000836",
                "InterPro-Name": "PRibTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 284,
                "End": 403
            },
            {
                "InterPro-ID": "IPR029055",
                "InterPro-Name": "Ntn_hydrolases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 264
            },
            {
                "InterPro-ID": "IPR000836",
                "InterPro-Name": "PRibTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 303,
                "End": 403
            },
            {
                "InterPro-ID": "IPR029057",
                "InterPro-Name": "PRTase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 286,
                "End": 451
            },
            {
                "InterPro-ID": "IPR029055",
                "InterPro-Name": "Ntn_hydrolases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 424
            },
            {
                "InterPro-ID": "IPR017932",
                "InterPro-Name": "GATase_2_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2,
                "End": 241
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR029057",
                "InterPro-Name": "PRTase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 259,
                "End": 488
            },
            {
                "InterPro-ID": "IPR000836",
                "InterPro-Name": "PRibTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 284,
                "End": 403
            },
            {
                "InterPro-ID": "IPR029055",
                "InterPro-Name": "Ntn_hydrolases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 264
            },
            {
                "InterPro-ID": "IPR005854",
                "InterPro-Name": "PurF",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 479
            },
            {
                "InterPro-ID": "IPR000836",
                "InterPro-Name": "PRibTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 303,
                "End": 403
            },
            {
                "InterPro-ID": "IPR029057",
                "InterPro-Name": "PRTase-like",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 286,
                "End": 451
            },
            {
                "InterPro-ID": "IPR029055",
                "InterPro-Name": "Ntn_hydrolases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 424
            },
            {
                "InterPro-ID": "IPR017932",
                "InterPro-Name": "GATase_2_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 2,
                "End": 241
            },
            {
                "InterPro-ID": "IPR035584",
                "InterPro-Name": "PurF_N",
                "InterPro-Type": "DOMAIN",
                "Beg": 2,
                "End": 273
            },
            {
                "InterPro-ID": "IPR005854",
                "InterPro-Name": "PurF",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 492
            },
            {
                "InterPro-ID": "IPR005854",
                "InterPro-Name": "PurF",
                "InterPro-Type": "FAMILY",
                "Beg": 2,
                "End": 479
            }
        ],
        "ipr_mapped": [
            464,
            114,
            115,
            461
        ],
        "response#1": "GRPRTGAETAAAGTARADADRADTADADGGSADRTGAGPAGTTPPAPAPPAPTRPTRPGPTRPDRAGTGRRAGPARRAGPAGPAPAAGPAGGAGPAGPAGRPAGPADRPRRAGPARPPARPADRPARPADRPADRAGPVGRAARPGRPGPGPAGRADRAGPARAGPDEAGPGEAGPGETGPGGPGQAGPADRPDPDQPDRAGRPDRPGRPDRAGGPPAGGRPAGGRPAGGRSAGAGSRDRRPGAAGARPPARRTGRPADSPAPAGRRRPGSGRRRAGRPAGRRAGPRPAGRRARPRSAGRRAGPRAGPRAAGRPGRRPARRPAAPRGAPDRTPGDRAPCRPGSRRP",
        "response#2": "AVAVAVAVAVAVAVAVVVAVAVAVVAVVVAVAVAVAVAAVVAVVVVAVVAVVAAVVAVVAVAVAVAVAVAVAVAVAVAAVVAAVVAVAVVAVVAAVAVAAVAAVAAVAAVAAVAAVAAVAVAAVAAVVAVADDDDDDDDDDDDDDDDDDDDDDDDDDDDDDGDDGDGDDDDDDDDDPPPPPRRRRPPRPPPRRRRRRRRPPPRRRPPPPPRRRRRRRRRRRRRRRRRRRRRRRRPPPPRPPPPPPAPPPPPPPPPPPPRPPRRRRDDDDDDGDDDDDDDPPPRR",
        "response#3": "MAAGATTRPATPTAPTPRTRARPTTTARRRRTCGTATCRPRRRSAPPYRRARRRRRRAATARRLPTARRRAPRRPSRPAPRRRPRTTRTARPPAPAPPRFAPPATPAPTATTAPTATAPATPPAAARRTTVAAGSPARPAATAVAAATAPHNCRRSARAAARTATHGSASSAPAPARAATRGPASQTPPPAVTSTTTTAAA"
    },
    {
        "reference": "MSTIRGTLSELSRAADAFAHEVDEAGYGDYTFLPDNSPFDLSFLTSKGLEARGSLIAAAEKILRLAKGPQGCLASFADTKGIEMGTIQALTQLEVPDKVPLQGSITYEELAGVIRVAPELLQRLVRLAALAGFLIEDESGAVRHTAMSAVFLRDTAAGDTARFLFDVDMRAYSFFADSLRLDPSGQNIGDGPTALAFQHDSDDQGNRPTIWDILERNPIQRARFHSTMQALGSFPSHLLKHILVAHDWHSIGSLVDVGGSLGHASLVIAENFPEIRITVQDLPDVVERGRSSLPTVPHAERVSFQAHDLFQEQAIIADAYFLRQILHDWPDGDAERIVRCLIPAMRPGAKLLIMDIVVPEPGAISPYMEKYLRTYDVSMFSMFSAKERTVQQLRDLVERCSARLQFQGISCPPGSATSLLSWVYSAE",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within SAM-dependent_MTases_sf, SAM-dependent_MTases_sf sharing conserved structural features; 2. The protein must be able to perform the methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008168",
                "GO-Name": "methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0008171",
                "GO-Name": "O-methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            20
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 208,
                "End": 400
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 165,
                "End": 418
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036388",
                "InterPro-Name": "WH-like_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 76,
                "End": 160
            },
            {
                "InterPro-ID": "IPR001077",
                "InterPro-Name": "O_MeTrfase_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 210,
                "End": 398
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 208,
                "End": 400
            },
            {
                "InterPro-ID": "IPR016461",
                "InterPro-Name": "COMT-like",
                "InterPro-Type": "FAMILY",
                "Beg": 75,
                "End": 421
            },
            {
                "InterPro-ID": "IPR029063",
                "InterPro-Name": "SAM-dependent_MTases_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 165,
                "End": 418
            },
            {
                "InterPro-ID": "IPR036390",
                "InterPro-Name": "WH_DNA-bd_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 84,
                "End": 154
            }
        ],
        "ipr_mapped": [
            70
        ],
        "response#1": "MARTEGDTWDLASSVGATATMVAAARAVATRSAKGLIDDPFAEPLVRAVGVDFFTRLASGELDLAEINTDSPGMQRMIDGMAIRTKFFDDFFLDATAAGIRQVVILASGLDSRAYRLPWPAGTVVYEIDQPQVIDFKTATLAELGATPAPTADRRTVAIDLRDDWPAALRAAGFDPAAPTAWIAEGLLIYLPPEAQDRLFDNITALSAPGSRLATEAMPDISTFDAERAKKYGLDMDMSALVYHGERNDARAWLAEHGWDAAATTVRELLARHGRPVPEDDDEFGAVRYVSALLR",
        "response#2": "MSSQPPPQPPPQQQQQQPPPPPPPPPPTPPAILIEADSDDARSVYAESITTSLASSILQYRFENGRTYHNYRYKEGKYFLPNDETEQDRLDLLHHIFTLTLDGKLYLAPLENPQRILDVGTGTGIMAIDVADKYPSAQVIGTDLSPIQPPTALVPPNLRFEVDDVEEPWTYPDNHFDLVHIRMLTGSIAADWPRLYSQVLRHLKPGGYFEQVEIDFIPRCDDDTLPPNPESEYPALAKWSNLLIEASDKFGRTLRIAKDTKKWMVDAGFVDVVETVYKWPLNPWPKDPHYKELGRWYNLALTEALEALSMAPFTRALGWTPTEIEVLLADVRKEIKARIHAYSNIHVIYGRKPE",
        "response#3": "MTDRPDTPPTPAPTPAAAAPDPATWDARYARGETPWDIGRPQPALVDLAESLPAGSRVLDVGCGTGTQSAFLAERGFTVTGIDISATAVERARERVPGARFEVADARALPFADGSFDAVVDSATFHAVPPADRPRYLGELRRVLAPGGRLHLLVFATEPDADAPDRAAARDVPVFRCTPAEITRLLTDAGLTDVATERVPLTVRPPRPDGADPTADEPDDAWRITATRP"
    },
    {
        "reference": "MERVLADALLTQSREPGELLGALCGGEASAERAETLRLVLQRLEERGAGAGALAKAAHEVARDHLVPLLHASQGGGPARPRVLRAASAALRSCARLAGPELAVTLAEEALRELPSAPAVELLAAVAPCLRAPEDAPLLRRLGRASVELALAGDAPPAVGARLLPALAQSAEPALRAAWDALSSAGPGAEGSTGPELLVLSALAEKLLTNHERHGDLDARLCGRFWRTVQAGLGRAQDGLTRKRARYLLQRAVQVSAELAVDCSCSPQDTKGPSLFWWSEKRKDELLKFWENYILIMEILEGNQIHVIKPALPKLNRLFECAVSEENGCWLFHPSWHTCIYKRMFESENKILAKEGVIHFLELYDVKSLPYSPELSEFITGPLMDALSESCLYSRSPGQPLGSDSPLGLKLQKFLVTYTSLLPEETKSCFLLKLIQRMADRHWCAVPVLFLSRALASIPSCKALGGEGLLALRDVLQRTMITHQVLLRGAAQCYLLQTAMRLVDVEKVSLSDISAFLLSLRQEESLGRGTVLWTELCDWLRVNERYFKQSSLGGSDGQEASLNAYVKNLVQEFVKSPGWEKESSFMPDWLDARLTALMVLLAVDVEGLKTKFREKQRTQNVLRIFLDPLLDALGKLGTNAYMPLLRTDRCLQLLVRLLHSCVPRRPGAQDDEVSTALQGSIMSASESVSQFVLRRLTMNELQDVADLDRCQLYLTVLSELMSLQVKLGWKAGNPISRVLSPLKNACVRHLQEAEDRQEPTLSHQVQRVVSMAALAALCEAVDQYPVLQPDSPNAEPVDRFLSALPLNHVLQKPRSEEQSIGVCPLENGSVFEESLSSKGWGKVVAQYLHDQWVCLSFLLRKHHHLIPSTESDVLEGFLPTAETPVQALQAALDVLTVLPAGRILPVFRCMEVLVPKLLTSEETLCIESFDVAWKIISSLSNTQLTFWPNLKAFVHFVFDHEILTIAAKLKGQVYFKIKEIMCKMIEMSSIKSGVFNILIRHCCQSWLVAASGVSQGSFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQGCAANVIIENAKREDYYVRICAIKFLCLLDGSDVSHKLFLEALAIKLLDKDESASRSRTRYHENSLQHRVKNRVWQTLLVLFPAFDQNFLHGIIDKVFHAGFTNNQASIKYFIEWLIILILHKFPEFLPKFWACFSYGEEKIKASICTFLSVLSHLDIIVQNIPEKKLVLKQALTVALQWCLSHNFSVRLYALVALKKAWHLCKTLQFEECGAWTAVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLETIFYTLPRLSGVTGEEWIALDKFANFTDIPSNAGSQWYLSGTALGELSPGDWSQQDQGSTLGEADSQSEWADVQKKIIPWGQSALESDLELEFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPSQLMNYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAEPPS",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within tRNA_m1G_MTases_N, Alpha/beta_knot_MTases sharing conserved structural features; 2. The protein must be able to perform the RNA binding,S-adenosylmethionine-dependent methyltransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding"
            },
            {
                "GO-ID": "GO:0008757",
                "GO-Name": "S-adenosylmethionine-dependent methyltransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003723",
                "GO-Name": "RNA binding "
            },
            {
                "GO-ID": "GO:0141100",
                "GO-Name": " tRNA (guanine(18)-2'-O)-methyltransferase activity "
            }
        ],
        "go_f_mapped": [
            96,
            302
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029026",
                "InterPro-Name": "tRNA_m1G_MTases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1422,
                "End": 1573
            },
            {
                "InterPro-ID": "IPR029028",
                "InterPro-Name": "Alpha/beta_knot_MTases",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1411,
                "End": 1571
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR016024",
                "InterPro-Name": "ARM-type_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 769,
                "End": 1257
            },
            {
                "InterPro-ID": "IPR045330",
                "InterPro-Name": "Trm3/TARBP1",
                "InterPro-Type": "FAMILY",
                "Beg": 4,
                "End": 1571
            },
            {
                "InterPro-ID": "IPR029026",
                "InterPro-Name": "tRNA_m1G_MTases_N",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1422,
                "End": 1573
            },
            {
                "InterPro-ID": "IPR056921",
                "InterPro-Name": "TARBP1_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 197,
                "End": 323
            },
            {
                "InterPro-ID": "IPR029028",
                "InterPro-Name": "Alpha/beta_knot_MTases",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 1411,
                "End": 1571
            },
            {
                "InterPro-ID": "IPR025806",
                "InterPro-Name": "Prob_MeTrfase_TARBP1",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 1579
            },
            {
                "InterPro-ID": "IPR001537",
                "InterPro-Name": "SpoU_MeTrfase",
                "InterPro-Type": "DOMAIN",
                "Beg": 1422,
                "End": 1563
            },
            {
                "InterPro-ID": "IPR044748",
                "InterPro-Name": "Trm3/TARBP1_C",
                "InterPro-Type": "DOMAIN",
                "Beg": 1422,
                "End": 1566
            }
        ],
        "ipr_mapped": [
            968,
            970
        ],
        "response#1": "MRAPSRRSRPASRSPRARSRPSAPASSAPPARARPRPRRSARRPSARSASSSAPRPASPPAPPAPAPPAPGPRSPRPRAARSSAASPPRSSAPRRASARPASAPARSAPRPARRPPARRSARSPASASRASRPAPASPSPRASRRPSRPARSPRSSARPRARRARARSAGGRAAAPSPAPARPSPRSRSRSPRAPAPAGRSPSARRAASARPRSRRPSPCAPSARSPPPAPARAPSRSARAAARSRSRRPARRSAAPSRRPAPAPAFSAPARPARAPRPAWPASRPAPSSASAPAAPRSARA",
        "response#2": "MTTPSTPTATAPGTPTTASAAASPSTPAASAPSTPSTPSATPSATPAAPSSPTSAPATATTASTAPGTPSATPSTPTTPSATPPTASSSPSATPAPSATPSTPTAPSATPSTASAASAAPSATPTTAPAASTPSSTPSATPSTASSTPSAPATPPATPSATPPSTPSTTPSTPAAATPSTPTASPTASATPSATTAPSSAPATATASSAPSAASATASAPSPTASATPTATPTTATAASATPSATPASASATPSATSATPSTPTAPSSTASAPSATPSSAPSTASPASPAPSAAATTAPATASSPSTPPATPPRTPAATPSPTASATPSAPSAAPPATPSPAATPTAATPRTRAR",
        "response#3": "MRPRRSAPAPDPRRDGRPRPARARARPRPAALAGPAAPAGRPGAGARRGPRGPADPARPRVRRAPDTAAAGAGRAPAGPGPGPGPGPGRAAGPGGRGARRAGGGRTRHPGRPAGAGAAGRAGGPGPGGPARGPPRTAPPAGGDAGPGRGAPGPGGPAGRGPGGRPAARRAPPPARPAAPGPAAPAPARRPRRARPGPAGPPAPGPGA"
    },
    {
        "reference": "MATYALSQAHREQMEKSLVDSDPEIAQIMEKEIQRQRESILLIASENVTSRAVFDALGSPMSNKYSEGYPGARYYGGNQHIDAIELTCQARALKAFNLDPEKWGVNVQCLSGSPANLEVYQALMRPHDRLMGLDLPHGGHLSHGYQTPSRKISAVSTYFETFPYRVNTETGIIDYDTLEANAELYRPKCLVAGTSAYCRLIDYGRMRKIADKVGAYLIVDMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVRSTDPKTGKEIMYDLEGPINFSVFPGHQGGPHNHTITALAVALKQAATPEFRQYQEQVLKNAKALEVEFKALGHKLVSDGTDSHMVLLDLRPKGLDGARVEAVLEQINIACNKNSIPGDKSALTPCGIRIGTPAMTSRGMSEEDFKRVARYIDQVINLCKSIQADLPKEANKLKDFKAKVASGSVPEILALRKEVAEWASTYPLPV",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more SHMT-like_dom that are essential for its biological function; 2. The protein should belong to Ser_HO-MeTrfase-like, Ser_HO-MeTrfase, Ser_HO-MeTrfase, Ser_HO-MeTrfase that shares evolutionary origin and functional similarity; 3. The protein should be classified within PyrdxlP-dep_Trfase, PyrdxlP-dep_Trfase_major, PyrdxlP-dep_Trfase_small sharing conserved structural features; 4. The protein should include a Ser_HO-MeTrfase_PLP_BS that enables ligand binding under diverse conditions; 5. The protein must be able to perform the glycine hydroxymethyltransferase activity,pyridoxal phosphate binding required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004372",
                "GO-Name": "glycine hydroxymethyltransferase activity"
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": "pyridoxal phosphate binding"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0004372",
                "GO-Name": "glycine hydroxymethyltransferase activity "
            },
            {
                "GO-ID": "GO:0030170",
                "GO-Name": " pyridoxal phosphate binding "
            }
        ],
        "go_f_mapped": [
            189,
            33
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 470
            },
            {
                "InterPro-ID": "IPR039429",
                "InterPro-Name": "SHMT-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 18,
                "End": 417
            },
            {
                "InterPro-ID": "IPR019798",
                "InterPro-Name": "Ser_HO-MeTrfase_PLP_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 241,
                "End": 257
            },
            {
                "InterPro-ID": "IPR049943",
                "InterPro-Name": "Ser_HO-MeTrfase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001085",
                "InterPro-Name": "Ser_HO-MeTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 463
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 47,
                "End": 321
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001085",
                "InterPro-Name": "Ser_HO-MeTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 471
            },
            {
                "InterPro-ID": "IPR001085",
                "InterPro-Name": "Ser_HO-MeTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 17,
                "End": 471
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR015424",
                "InterPro-Name": "PyrdxlP-dep_Trfase",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 9,
                "End": 470
            },
            {
                "InterPro-ID": "IPR039429",
                "InterPro-Name": "SHMT-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 18,
                "End": 417
            },
            {
                "InterPro-ID": "IPR019798",
                "InterPro-Name": "Ser_HO-MeTrfase_PLP_BS",
                "InterPro-Type": "BINDING_SITE",
                "Beg": 241,
                "End": 257
            },
            {
                "InterPro-ID": "IPR049943",
                "InterPro-Name": "Ser_HO-MeTrfase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001085",
                "InterPro-Name": "Ser_HO-MeTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 20,
                "End": 463
            },
            {
                "InterPro-ID": "IPR015421",
                "InterPro-Name": "PyrdxlP-dep_Trfase_major",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 47,
                "End": 321
            },
            {
                "InterPro-ID": "IPR015422",
                "InterPro-Name": "PyrdxlP-dep_Trfase_small",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 22,
                "End": 470
            },
            {
                "InterPro-ID": "IPR001085",
                "InterPro-Name": "Ser_HO-MeTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 3,
                "End": 471
            },
            {
                "InterPro-ID": "IPR001085",
                "InterPro-Name": "Ser_HO-MeTrfase",
                "InterPro-Type": "FAMILY",
                "Beg": 17,
                "End": 471
            }
        ],
        "ipr_mapped": [
            73,
            74,
            75,
            494,
            495,
            496,
            497
        ],
        "response#1": "VRLRGRGRATLSHITLSEKERKELEKKINSAVFPGIQGGPLMHIIAGKAVAFGEALKDEFKEYQEQVVKNAKALAETLQKKGYDIVSGGTDNHLMLVDLRPKDITGKRAEDALERAGITVNKNTIPFDKSPFVTGGIRLGTPAVTTRGMKEDEMEKIAEFIDRVLTNLRKPDGEENPEVDEEVEKEVREQVKELCDRFPLYPDVELE",
        "response#2": "DTVMGMNLSQGGHLTHGSPVNFSSKLYNFIPYGVNPETEMIDYAEVERLAKEHKPKMIVAGASAYPRIVDWAKMRAIADSIGAYLMVDMAHYAGLVAAGLYPNPVPHADFVTTTTHKTLRGPRGGVILMKAEYEKAINSAIFPGIQGGPLMHVIAAKAVAFKEALQPEFKVYQEQVAKNAKVMVEVFLERGYKVVSGGTDNHLMLIDLVDKDITGKEADAALGRANITVNKNSVPNDPRSPFVTSGVRIGTPAGTTRGFKEVEMKELAGWMCDVLDNINDEAVIERIKAKVLDICARFPVYDGLEYVAA",
        "response#3": "EVKELFGATYANVQPHSGSQANFAVYTALLEPGDTVLGMNLSHGGHLTHGSPVNFSGKLYNIVPYGVDKETELIDYDEVERLAKEHKPKMIVAGASAYSRVIDWAKFREIADSVGAYLMVDMAHIAGLVAAGVHPNPVPHAHVVTTTTHKTLRGPRGGLILTNDESLAKKINSAVFPGLQGGPLMHVIAGKAVAFKEALEPEFKVYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKDITGKEADAALGRANITVNKNSVPNDPKSPFVTSGVRLGTPAITTRGFKEAEAKELAGWMCDVLDNINDEAVIERIKAKVLDICARLPVYGA"
    },
    {
        "reference": "MRSPASTPSIRGGAFASSPILRHNHLPFLRLNPPSSSPTRSSPPSIQCSVQFRPCIDIHKGKVKQIVGSTLKDLKDDDGSDPITNFESDKSAAEYATLYKQDGLKGGHVIMLGADPFSKAASLEALHAYPGGLQVGGGINSDNCLSYIEEGASHVIVTSYVFNNGQMDLERLKDLVRIVGKERLVLDLSCRKKEGKYAIVTDRWQKFSDVSLDAKVMEFLANFADEFLVHGVDVEGKKLGIDEELVALLGKHSPIPVTYAGGVTVMDDLERIRTAGMDNVDVTVGSALDIFGGNLAYKDVVAWHNQQKVSVA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should belong to Isoase_HisA-like, His_biosynth that shares evolutionary origin and functional similarity; 2. The protein should be classified within RibuloseP-bd_barrel, Aldolase_TIM sharing conserved structural features; 3. The protein must be able to perform the 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003949",
                "GO-Name": "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0003949",
                "GO-Name": "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity "
            }
        ],
        "go_f_mapped": [
            209
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR011060",
                "InterPro-Name": "RibuloseP-bd_barrel",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 51,
                "End": 303
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 50,
                "End": 308
            },
            {
                "InterPro-ID": "IPR044524",
                "InterPro-Name": "Isoase_HisA-like",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 308
            },
            {
                "InterPro-ID": "IPR006062",
                "InterPro-Name": "His_biosynth",
                "InterPro-Type": "FAMILY",
                "Beg": 54,
                "End": 288
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR011060",
                "InterPro-Name": "RibuloseP-bd_barrel",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 51,
                "End": 303
            },
            {
                "InterPro-ID": "IPR013785",
                "InterPro-Name": "Aldolase_TIM",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 50,
                "End": 308
            },
            {
                "InterPro-ID": "IPR044524",
                "InterPro-Name": "Isoase_HisA-like",
                "InterPro-Type": "FAMILY",
                "Beg": 51,
                "End": 308
            },
            {
                "InterPro-ID": "IPR006062",
                "InterPro-Name": "His_biosynth",
                "InterPro-Type": "FAMILY",
                "Beg": 54,
                "End": 288
            },
            {
                "InterPro-ID": "IPR011858",
                "InterPro-Name": "His6-like_euk",
                "InterPro-Type": "FAMILY",
                "Beg": 50,
                "End": 304
            }
        ],
        "ipr_mapped": [
            552,
            554,
            101,
            550
        ],
        "response#1": "MIVIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPDVVKGWFERFGAQALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTGVRGVIVGRALLEGKFTVKEAIQCWQPGKRWDDLPDLPDGGDENA",
        "response#2": "MLLIPAIDLKDGQCVRLKQGDMDQATIFSEDPVAMARKWVDLGARRLHLVDLNGAFAGKPVNGEIVKLIAGEYPDLPIQIGGGIRSLETIEKYLDAGVSYVIIGTAAVKEPGFLRDACSAFSGHIIVGLDAKDGKVATDGWSKLTGHDVVDLAKKFEDYGCESIHYTDIGRDGLLKGINLSAVEKLLDAVNIPVQIGGGIRNLEDIEKYLDRGLSYVIIGTAAVKNPGFLKDACSAFSGHIIVGLDAKDGKVATDGWSKLTGHEVIDLAKKFEDYGVESIIYTDIGRDGMLQGINIEATVKLAQAVGIPVIASGGLSNIVDIEKLCEVEEEGVEGVICGRAIYEGTLDFAAAQKRADELNGA",
        "response#3": "MLLIPAIDLKDGQCVRLKQGDMDQATVFSEDPVAMARKWVDLGARRLHLVDLNGAFAGKPVNGEVVEAIAGRYPDLPIQIGGGIRSLETIEKYLDAGVSYVIIGTKAVKDPGFVQDACSAFSGSIIVGLDAKDGKVATDGWSKLTGHEVIDLARKFEDYGVESIVYTDIGRDGMLQGINIEATVKLAQAVGIPVIASGGLSNIVDIEKLCEVEEQGVEGVICGRAIYSGDLDFAAAQKRAGSNWWQELAEADLFQFTGDLEGDDNA"
    },
    {
        "reference": "MSLSLNEYLRYGRQLIVPEFGLQGQISLKNSRVLVVGAGGLGCPALQYLVGAGFGTVGIVDHDTVDISNLHRQILHTSETVEMLKCESAKLQLAKLNPLVQINTHPVALSPDNSFGIFEQYDIILDCTDTPATRYLINDTAVLLGLTVISGSGLKTEGQLSILNFNNTGPCYRCFYPTPPPPSSVTACSDGGVLGPVIGIMGVMMALEAIKVVSGYYLREDVEFQPFLSLYSGYGPLQSLRTFKMRRRSPKCRVCNAGTREITRHVIETELDYAVWCGKMDYNVLEKDERVSVEQLSAQRAPYLVDVRAKEQYSIVHLPNSINIPLNALKHMDTLDVPKETMIYVICRFGNDSQLAVKHLKSIGYENCVDVIGGLTQWSRQIDPNFPIY",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should contain one or more Rhodanese-like_dom, Rhodanese-like_dom, Rhodanese-like_dom that are essential for its biological function; 2. The protein should be classified within Rhodanese-like_dom_sf sharing conserved structural features; 3. The protein must be able to perform the nucleotidyltransferase activity,nucleotide binding,cation binding,thiosulfate-cyanide sulfurtransferase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016779",
                "GO-Name": "nucleotidyltransferase activity"
            },
            {
                "GO-ID": "GO:0000166",
                "GO-Name": "nucleotide binding"
            },
            {
                "GO-ID": "GO:0043169",
                "GO-Name": "cation binding"
            },
            {
                "GO-ID": "GO:0004792",
                "GO-Name": "thiosulfate-cyanide sulfurtransferase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0070566",
                "GO-Name": "adenylyltransferase activity "
            },
            {
                "GO-ID": "GO:0005524",
                "GO-Name": " ATP binding "
            },
            {
                "GO-ID": "GO:0046872",
                "GO-Name": " metal ion binding "
            },
            {
                "GO-ID": "GO:0004792",
                "GO-Name": " thiosulfate-cyanide sulfurtransferase activity "
            },
            {
                "GO-ID": "GO:0042292",
                "GO-Name": " URM1 activating enzyme activity "
            }
        ],
        "go_f_mapped": [
            122,
            61,
            183,
            187
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR001763",
                "InterPro-Name": "Rhodanese-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 288,
                "End": 384
            },
            {
                "InterPro-ID": "IPR036873",
                "InterPro-Name": "Rhodanese-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 290,
                "End": 389
            },
            {
                "InterPro-ID": "IPR001763",
                "InterPro-Name": "Rhodanese-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 297,
                "End": 380
            },
            {
                "InterPro-ID": "IPR001763",
                "InterPro-Name": "Rhodanese-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 298,
                "End": 387
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR035985",
                "InterPro-Name": "Ubiquitin-activating_enz",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 2,
                "End": 356
            },
            {
                "InterPro-ID": "IPR001763",
                "InterPro-Name": "Rhodanese-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 288,
                "End": 384
            },
            {
                "InterPro-ID": "IPR000594",
                "InterPro-Name": "ThiF_NAD_FAD-bd",
                "InterPro-Type": "DOMAIN",
                "Beg": 11,
                "End": 254
            },
            {
                "InterPro-ID": "IPR036873",
                "InterPro-Name": "Rhodanese-like_dom_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 290,
                "End": 389
            },
            {
                "InterPro-ID": "IPR001763",
                "InterPro-Name": "Rhodanese-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 297,
                "End": 380
            },
            {
                "InterPro-ID": "IPR045886",
                "InterPro-Name": "ThiF/MoeB/HesA",
                "InterPro-Type": "FAMILY",
                "Beg": 7,
                "End": 293
            },
            {
                "InterPro-ID": "IPR028885",
                "InterPro-Name": "MOCS3/Uba4",
                "InterPro-Type": "FAMILY",
                "Beg": 1,
                "End": 389
            },
            {
                "InterPro-ID": "IPR001763",
                "InterPro-Name": "Rhodanese-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 298,
                "End": 387
            }
        ],
        "ipr_mapped": [
            489,
            490
        ],
        "response#1": "MRREEAAEREAARARLRRRLAEALRRLPPESRLARERERLRRLDPELAGRLALDERLVEAYAGPGDPAEARRRLLELARRLPRAGGEPEAIRLAAEREAPRLHLEAPEAVALDAERERLRRAAEALLELDPEAALALYLEPEGEERLERRLAGELPAGAAREAAARRLARAWRREERERAGLALRLPGTRRLALALAEAARFAEARLEALGLPARPGPGPRALAEELAARRLAPAEREEAWRELEQRLGRAGALERELAERLRRGLEAPPEERLAERLRPEARPELQRLAEAEARVEALLERELRRRRPELARALREPLLDREVRRLRRRLLEALEAGDAGRRREEALRAAEELEAAEALLRRAEERLRREELERPEPERLLRGG",
        "response#2": "MKGIINNENLKKIKEEIYKLMIINKEKSLEILKKDENINLIYNLLNKNDEENLKERENNKVEAKINENIINNILINLNEKENKEKEINNNNQNKEENKKNDNINNKNENIKIKNNDINNDYKNDEEKIYLNKLYEKLSKNKIKEEELESNNKNEKTENPNKENKINNIKEKEKYDNIDNNNNYKEEIEENILNKIKINNLNNLNENKVKIDNEEEKIININK",
        "response#3": "MNKKIKKINNRINKEEESEEKIIKNNIEYENINIKNIKKEIKKEYLVFENEKNNNYSLIGNINLNKEILKKNNNERNKNKINIDLNKEYENENIYNIENEQYNNKKEEKNDIIVKNKKEINFEIDKIKNYIIENLIKNIEILNGKENIINELENKEKNNINLINIDENKEKINNEEENINNNIKIEENIENENKYLIDNIKKIKIEKE"
    },
    {
        "reference": "MANILENQLFTAAKTIEQQLDQQLDRLDNLDSDDLKVLREQRLREMKDLNNKKQEWLRNGHGTYTELADEKEFFEMSKKSPNIVCHFYRDSTERCKIVDMHLKILAAKHVEAKFCKVNAEKTPFLTQRLRIKVIPTIALVKDSKTKDFIVGFTDLGNCDDFATEMLEWRIAHSGAIDYKGDLMQPPDVKRKPFINRPQKTIRGGYDSDDSDIDLDD",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within Thioredoxin-like_sf sharing conserved structural features; 2. The protein must be able to perform the protein folding chaperone required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0044183",
                "GO-Name": "protein folding chaperone"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0044183",
                "GO-Name": "protein folding chaperone "
            }
        ],
        "go_f_mapped": [
            215
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR036249",
                "InterPro-Name": "Thioredoxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 177
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR036249",
                "InterPro-Name": "Thioredoxin-like_sf",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 3,
                "End": 177
            },
            {
                "InterPro-ID": "IPR024253",
                "InterPro-Name": "Phosducin_thioredoxin-like_dom",
                "InterPro-Type": "DOMAIN",
                "Beg": 29,
                "End": 163
            }
        ],
        "ipr_mapped": [
            185
        ],
        "response#1": "MADRSDDDDDRFDAIRERILEEARERAEEIREEARERAEDIREEARREAEERAEDIREEAEREAEARAEEIREEAEREAEERRRRERREAVLETKRRLLEERRRILDDVRERVEDRLEDSAEDARAAVRDSERYLDLVAELLRDALESLDEEEVTIRVHPNDRDLLEDRVDRLRADVGFDGSLSVEPADGDLAGGVEVVSDDGSVRYVNTLESRFERARDELRPRIVRALFEELE",
        "response#2": "MNLFSILLLASVSWLCLAEEAPAAAPPVPTQEEKQRQAEEIKRRQEEMQERLRQLREAGVPMPPELKEKLKQQQEEMKKQQEQAAEAAAAAPAAAAAEEEEPEETEEEEEELSPQAQEQLLQQMQQLKQLQAQKTRQQLQQQLQQLKQPPAQTPATPAAAQKPTQESVQQPPQQQSTPPQRQQDITPEKLQELIQEAKKDPEKRAELERELSSAMS",
        "response#3": "ENENKIKDLQKQIEDLKKEKQQLEDQLNQKNNENNNKIQELKNQIEELKKQKQELEQKLQQLEQQLKNKQKELEELKNNNNNNNQKIEELKKQIQEKEKQIEELKKQNEELQKQKQELEQKVKQLEEQLNQKNQENNENENKIKELQNKIEELQKEKQQLEEKLKNNEEIEKLKNQLNEKNNENNNKIQELQKQIEELKQQKQELEQKLEELKNENNKNNNNQEEINKLKQEIEQLKQQLQQNQSQLQEKQKQLEELQQQKKQLEEQLKQKQENNNNDQKIQELKQQIEQLKQQLQQKEEKLKQLEEKLKQLEEKLNELKAK"
    },
    {
        "reference": "MTHWAFSPIQPGAARNMAAWQIAGKKDGPYQIDVSWPLTWSESGDASGKSANAVYLVDGNALFLTATETLRRRESHRPSETGTVVIAIGYPITDSVFSPRRSYDLTPPCDHYIPPEGPDGSPKPEAHGGADEFLTFIAEIVRPFVELKVFPRVSFGRTALFGHSYGGLFALHALFTKPSSFDVYLAASPSIWWNNRSILTEARRFISGAALFSSAHPVLRLSFGSREQYPVRQRVESDEMFKRRQRAAEQRRMNDNCEELYSELLASGRLCKLEVKEYLDEDHGSVIGPALSGGIMFLSNLSA",
        "instruction": "Generate a protein sequence for a novel protein that integrates the following function keywords: 1. The protein should be classified within AB_hydrolase_fold, AB_hydrolase_fold sharing conserved structural features; 2. The protein must be able to perform the hydrolase activity required for its activity.. The designed protein sequence is ",
        "Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016787",
                "GO-Name": "hydrolase activity"
            }
        ],
        "[Previous]Gene Ontology (molecular function)": [
            {
                "GO-ID": "GO:0016788",
                "GO-Name": "hydrolase activity, acting on ester bonds "
            }
        ],
        "go_f_mapped": [
            19
        ],
        "InterPro": [
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 298
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 301
            }
        ],
        "[Previous]InterPro": [
            {
                "InterPro-ID": "IPR000801",
                "InterPro-Name": "Esterase-like",
                "InterPro-Type": "FAMILY",
                "Beg": 46,
                "End": 200
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 23,
                "End": 298
            },
            {
                "InterPro-ID": "IPR029058",
                "InterPro-Name": "AB_hydrolase_fold",
                "InterPro-Type": "HOMOLOGOUS_SUPERFAMILY",
                "Beg": 15,
                "End": 301
            },
            {
                "InterPro-ID": "IPR052558",
                "InterPro-Name": "Siderophore_Hydrolase_D",
                "InterPro-Type": "FAMILY",
                "Beg": 6,
                "End": 299
            }
        ],
        "ipr_mapped": [
            35
        ],
        "response#1": "MIKINNLKINYQIKGKGKPIIFIHGFGLSSKIWEKNIKFFSKYFKVYALDLPGFGKSPKKQNFSLKDYEKIIISFLKHKKIKKCTLVGHSFGGIISILTTLKHPQFIEKLILSGTSLKIKEKSLLKQVKLILLFPFISFFLSKKEIEIFKKEIKKIDLTKELKKIEAKTLILWCKKDKLIPLKNAKIINQNIKNSKLKILNCGHSPFMEKPKEFNKEVLKFLKN",
        "response#2": "MTTTSRTARPAPRRPRRPAPPRGATAAAGPAATATAAAGTAATAAAAAATTAASAARTRTRGRYVRTGHGRIFVRTAGRRGPTVLLVHGIGASSDVWRLLLPALARRHRVVALDLLGFGRSDKPRDPRRTYDLADQAARLREVLDALDVREPVHAVGHSLGAFVCAELAAREPERFASLTLLSGTTRLRPPRRAPAPAPDAPPPAPAPRPGPAARAAAAVRAAPLPVLGAAGAVAARVPGLLRLLTRFAVAPGADPAFVADFTRHATTCDPRTLAAAFRASAAHDLAPVAAAIGVPVLLLHGTADRLVPPAEGRELHRLLGPRARLHLLDGVGHLPMWERPEEVAALIDRHLPRRPAAPRRPAAPRRPAAPRRPAAP",
        "response#3": "MRRAALLAALLLAAACRRPPPPPPLPPPRPPAAPPPPPPPPPPPPPPPPPPPPPPPRALAPRPAPPPGWREGYVEANGVRLHYLAVGEGPAVVLHHGWGGDATLWWLQARALARAGYRVVLYDLRGHGRSDKPPGPYTLEDHVADLEALRRALGLERVVLVGHSMGGAVALLYTARHPERVAALVLVDTAPSLPFPPPRRPPPPPPPGPPPGPEGLSREELLRRLEEARRTPPDPRLRERILALWREVTADPEEAARRFARSNFAPDAPPELVEWWTRRVAESDPAARAAFFEAWSRVDLRPLLPRVRVPTLVVHGRRDPLVPLEYGEEMARLIPGARLVVLERSAHAPPVEEPEGFNRAVLEFLRELPPPRR"
    }
]