The structure contains a saturated six-membered piperidine ring (Ring A) with nitrogen at position 1 and two chiral carbons at positions 4 and 6:
- At Ring A position 4 (chiral center, R configuration), a trifluoromethyl group (-CF3) is attached.
- At Ring A position 6 (also a chiral, S configuration), a pyridine ring (an aromatic ring with five carbons and one nitrogen) substituent is attached with the ring nitrogen at the meta position of the attachment.
The nitrogen at position 1 of Ring A connects to a methylene (-CH2-) linker, extending to another chiral carbon (R configuration). This carbon is part of a six-membered heterocyclic ring (Ring B) containing one oxygen and five carbons, with the oxygen located opposite the chiral carbon. Additionally, two carbon atoms (C-alpha and C-beta) between the oxygen and the chiral carbon are shared with a benzene ring (Ring C). Here, the oxygen can be considered a C-alpha substituent, and the carbon in Ring C opposite C-alpha is further substituted with a fluorine atom. Another carbon in Ring C opposite C-beta is bonded to a sulfonamide group (-SO2NH-), which extends into a five-membered aromatic heterocycle (a thiazole ring) containing one nitrogen and one sulfur. In this heterocycle, the nitrogen and sulfur are separated by a carbon atom that is connected to the NH group of the sulfonamide.