The issue focused on healthy aging should not be weighed against clinical significance The consensus message from science appears to be that adequate nutrients do not alter aging processes at levels sufficient to reverse aging processes The consensus message from clinical science appears to be that prolonged calorie restriction appears to decrease longevity but weight loss appears to reverse aging processes However, weight loss appears to reverse aging processes through regulating mitochondria replacement rates through mitochondrial scaling Energy expenditure appears to remain unchanged following caloric restriction Consistent with published literature (including reviews), elevated lifespan following caloric restriction appears