The issue focused on possible biological mechanisms by which variations in gene expression may influence illness outcome. From arXiv:0904.05758 [gr-qc] [expires: 2017-04-05] Full text available at: http://arxiv.org/abs/0904.05758 Some phenotypic variation is useful for identifying gene networks that control disease outcome. These networks may hold critical clues for improving clinical diagnosis and therapy. Here we identify specific genes that show genetic variations associated