The issue focused on the problem of how to grow "man-made" biocatalysts. The author has been working on the problem for the last 10 years, and is not new to the field. The author's name is John F. Kress, and he is a professor of plant biochemistry and systems biology at the University of California, Davis. The author's main problem is to find a way to make it possible to grow all the various complex systems in the world. The author's main