First induction of anesthesia, transoral endotracheal intubation using a laser tube by the anesthesia colleagues. Positioning of the patient by the surgeon. Laryngoscopy performed using a Kleinsasser C-tube. Inconspicuous conditions there. Inspection of the supraglottis revealed an exophytic mass covered by rough mucosa, which subtotally occupied the laryngeal surface of the epiglottis and completely invaded the pharyngoepiglottic fold laterally. Clamping of the spreading laryngoscope and adjustment of the findings. Setting the CO2 laser to a power of 6 W in continuous mode and successive traversing of the findings, which were removed using the piecemeal technique. Subsequently, three marginal samples were taken (central tongue base, right lateral pharyngeal side wall, right posterior pharyngeal side wall). In the third marginal sample ( pharyngeal lateral wall right posterior ), focal CIS parts were detected by the pathology colleagues. Thus, generous resection in this region and removal of a second marginal sample at the same site. Both the resected specimen and the second marginal specimen were sent for final histology. Hemostasis there by means of bipolar coagulation. An arterial vessel was treated three times with a clip. Repeated inspection. Dry conditions. Completion of the procedure without complications. The patient was to be fed exclusively via PEG for the next 7 days.