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}

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	year = {2020},
	doi = {10.1212/WNL.0000000000009910},
	publisher = {Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology},
	issn = {0028-3878},
	URL = {https://n.neurology.org/content/95/5/e532},
	eprint = {https://n.neurology.org/content/95/5/e532.full.pdf},
	journal = {Neurology}
}

@article {Seeley,
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 }
 
 @article {Villemagne,
  author = {Victor L. Villemagne and Vincent Dor\'{e} and Samantha C. Burnham, Colin L. Masters, Christopher C. Rowe},
  title = {Imaging tau and amyloid-$\beta$ proteinopathies in Alzheimer disease and other conditions},
  volume = {14},
  number = {4},
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  doi = {10.1038/nrneurol.2018.9},
  year = {2018},
  journal = {Nature reviews. Neurology.}
 }
 
  @article {Villemagne_amy,
  author = {Villemagne, Victor L. and Burnham, Samantha and Bourgeat, Pierrick and Brown, Belinda and Ellis, Kathryn A. and Salvado, Olivier and Szoeke, Cassandra and Macaulay, S Lance and Martins, Ralph and Maruff, Paul and Ames, David and Rowe, Christopher C. and Masters, Colin L.},
  title = {Amyloid $\beta$ deposition, neurodegeneration, and cognitive decline in sporadic 
      Alzheimer's disease: a prospective cohort study},
  volume = {12},
  number = {4},
  pages = {357--67},
  doi = {10.1016/S1474-4422(13)70044-9},
  year = {2013},
  journal = {The Lancet. Neurology}
 }
 
 @article {Palop2010,
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 year = {2010},
 doi = {10.1038/nn.2583},
 URL = {https://doi.org/10.1038/nn.2583},
 journal = {Nature Neuroscience}
 }
 
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 }
 
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 journal = {Neuron}
 }
 
 @INPROCEEDINGS{diff_distance,
  author={Huang, Weiyu and Segarra, Santiago and Ribeiro, Alejandro},
  booktitle={2015 49th Asilomar Conference on Signals, Systems and Computers}, 
  title={Diffusion distance for signals supported on networks}, 
  year={2015},
  volume={},
  number={},
  pages={1219--1223},
  doi={10.1109/ACSSC.2015.7421335}
  }

@inproceedings{cho-etal-2014-learning,
    title = "Learning Phrase Representations using {RNN} Encoder{--}Decoder for Statistical Machine Translation",
    author = {Cho, Kyunghyun  and
      van Merri{\"e}nboer, Bart  and
      Gulcehre, Caglar  and
      Bahdanau, Dzmitry  and
      Bougares, Fethi  and
      Schwenk, Holger  and
      Bengio, Yoshua},
    booktitle = "Proceedings of the 2014 Conference on Empirical Methods in Natural Language Processing ({EMNLP})",
    month = oct,
    year = "2014",
    address = "Doha, Qatar",
    publisher = "Association for Computational Linguistics",
    url = "https://www.aclweb.org/anthology/D14-1179",
    doi = "10.3115/v1/D14-1179",
    pages = "1724--1734",
}

@inproceedings{Gao2019GraphU,
  title={Graph U-Nets},
  author={Gao, Hongyang and Ji, Shuiwang},
  booktitle={ICML},
  year={2019}
}

@article{rodrigue2012,
 author = {Rodrigue, K. M. and Kennedy, K. M. and Devous, M. D. and Sr, Rieck, J. R. and Hebrank, A. C. and Diaz-Arrastia, R. and Mathews, D. and Park, D. C.},
 title = {$\beta$-Amyloid burden in healthy aging: regional distribution and cognitive consequences},
 volume = {53},
 number = {1},
 pages = {1–-15},
 year = {2010},
 doi = {10.1016/j.neuroimage.2010.06.010},
 journal = {Neurology}
}

@article{Atasoy2016,
 author = {Atasoy, Selen and Donnelly, Isaac and Pearson, Joel},
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 year = {2016},
 doi = {10.1038/ncomms10340},
 url = {https://doi.org/10.1038/ncomms10340},
 journal = {Nature Communications}
}

@article{fs,
 author = {Destrieux, Christophe and Fischl, Bruce and Dale, Anders and Halgren, Eric},
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 pages = {387–-395},
 year = {2012},
 URL = {https://doi.org/10.1212/WNL.0b013e318245d295},
 journal = {Neuroimage}
}

@article{probtrackx,
 author = {Behrens, T.E. and Berg, H. Johansen and Jbabdi, S. and Rushworth, M.F. and Woolrich, M.W.},
 title = {Probabilistic diffusion tractography with multiple fibre orientations: What can we gain?},
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 pages = {144–-55},
 year = {2007},
 doi = {10.1016/j.neuroimage.2006.09.018},
 journal = {Neuroimage}
}

@ARTICLE{Wu2021,
AUTHOR={Wu, Zhanxiong and Peng, Yun and Hong, Ming and Zhang, Yingchun},
TITLE={Gray Matter Deterioration Pattern During Alzheimer's Disease Progression: A Regions-of-Interest Based Surface Morphometry Study},
JOURNAL={Frontiers in Aging Neuroscience},
VOLUME={13},
PAGES={23},
YEAR={2021},
URL={https://www.frontiersin.org/article/10.3389/fnagi.2021.593898},
DOI={10.3389/fnagi.2021.593898},
ISSN={1663-4365},   
}

@article{dickerson,
 author = {Dickerson, Bradford C. and Bakkour, Akram and Jbabdi, S. and Salat, David H. and Feczko, Eric and Pacheco, Jenni and Greve, Douglas N. and Grodstein, Fran and Wright, Christopher I. and Blacker, Deborah and Rosas, H. Diana and Sperling, Reisa A. and Atri, Alireza and Growdon, John H. and Hyman, Bradley T. and Morris, John C. and Fischl, Bruce and Buckner, Randy L.},
 title = {The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals},
 volume = {19},
 number = {3},
 pages = {497-–510},
 year = {2008},
 doi = {10.1093/cercor/bhn113},
 journal = {Cereb Cortex}
}

@ARTICLE{smith02,
AUTHOR={Smith, A. David and Peng, Yun and Hong, Ming and Zhang, Yingchun},
TITLE={Imaging the progression of Alzheimer pathology through the brain},
JOURNAL={Proc Natl Acad Sci U S A},
VOLUME={99},
NUMBER={7},
PAGES={4135--7},
YEAR={2002},
DOI={10.1073/pnas.082107399} 
}

@ARTICLE{Vogel2020,
AUTHOR={Vogel, Jacob W. and Iturria-Medina, Yasser and Strandberg, Olof T. and Smith, Ruben and Levitis, Elizabeth and Evans, Alan C. and Hansson, Oskar and Alzheimer’s Disease Neuroimaging Initiative and the Swedish BioFinder Study},
TITLE={Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease},
JOURNAL={Nature Communications},
VOLUME={11},
NUMBER={1},
PAGES={2612},
YEAR={2020},
DOI={10.1038/s41467-020-15701-2},
URL={https://doi.org/10.1038/s41467-020-15701-2}
}

@ARTICLE{fan2018,
AUTHOR={Fan, Ling-Yun and Tzen, Kai-Yuan and Chen, Ya-Fang and Chen, Ta-Fu and Lai, Ya-Mei and Yen, Ruoh-Fang and Huang, Ya-Yao and Shiue, Chyng-Yann and Chiu, Ming-Jang},
TITLE={The Relation Between Brain Amyloid Deposition, Cortical Atrophy, and Plasma Biomarkers in Amnesic Mild Cognitive Impairment and Alzheimer's Disease},
JOURNAL={Front Aging Neurosci},
VOLUME={10},
PAGES={175},
YEAR={2018},
DOI={10.3389/fnagi.2018.00175},
URL={https://pubmed.ncbi.nlm.nih.gov/29967578}
}

@article {Canter116244,
	author = {Canter, R.G. and Choi, H. and Wang, J. and Watson, L.A. and Yao, C.G. and Abdurrob, F. and Bousleiman, S.M. and Delalle, I. and Chung, K. and Tsai, L-H.},
	title = {3D Mapping Reveals Network-specific Amyloid Progression and Subcortical Susceptibility},
	elocation-id = {116244},
	year = {2017},
	doi = {10.1101/116244},
	publisher = {Cold Spring Harbor Laboratory},
	abstract = {Alzheimer{\textquoteright}s disease is a progressive, neurodegenerative condition for which there is no cure. Prominent hypotheses posit that accumulation of beta-amyloid (Aβ) peptides drives the neurodegeneration that underlies memory loss, however the spatial origins of the lesions remain elusive. Using SWITCH, we created a spatiotemporal map of Aβ deposition in a mouse model of amyloidosis. We report that structures connected by the fornix show primary susceptibility to Aβ accumulation and demonstrate that aggregates develop in increasingly complex networks with age. Notably, the densest early Aβ aggregates occur in the mammillary body coincident with electrophysiological alterations. In later stages, the fornix itself also develops overt Aβ burden. Finally, we confirm Aβ in the mammillary body of postmortem patient specimens. Together, our data suggest that subcortical memory structures are particularly vulnerable to Aβ deposition and that functional alterations within and physical propagation from these regions may underlie the affliction of increasingly complex networks.Author Contributions RGC, KC, L-HT, ID conceived of the work and planned the experiments.RGC, HC, JW, LAW, CGY, FA, SMB performed experiments and analyzed data.HC built the custom microscope.RGC, L-HT, KC, ID wrote the manuscript.},
	URL = {https://www.biorxiv.org/content/early/2017/03/19/116244},
	eprint = {https://www.biorxiv.org/content/early/2017/03/19/116244.full.pdf},
	journal = {bioRxiv}
}
@inproceedings{Kipf:2016tc,
  added-at = {2020-07-15T00:50:01.000+0200},
  author = {Kipf, Thomas N. and Welling, Max},
  biburl = {https://www.bibsonomy.org/bibtex/271ee5be8cafc25d7a3869bcb49fc5c3c/twagener},
  booktitle = {Proceedings of the 5th International Conference on Learning Representations},
  interhash = {54b65044b71f10c31476ed76422ab85d},
  intrahash = {71ee5be8cafc25d7a3869bcb49fc5c3c},
  keywords = {},
  location = {Palais des Congr{\`e}s Neptune, Toulon, France},
  series = {ICLR '17},
  timestamp = {2020-07-15T00:50:01.000+0200},
  title = {{Semi-Supervised Classification with Graph Convolutional Networks}},
  url = {https://openreview.net/forum?id=SJU4ayYgl},
  venue = {ICLR},
  year = 2017
}

@article {Solfrizzi433,
	author = {Solfrizzi, Vincenzo and Scafato, Emanuele and Capurso, Cristiano and D{\textquoteright}Introno, Alessia and Colacicco, Anna Maria and Frisardi, Vincenza and Vendemiale, Gianluigi and Baldereschi, Marzia and Crepaldi, Gaetano and Di Carlo, Antonio and Galluzzo, Lucia and Gandin, Claudia and Inzitari, Domenico and Maggi, Stefania and Capurso, Antonio and Panza, Francesco},
	title = {Metabolic syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Ageing},
	volume = {81},
	number = {4},
	pages = {433--440},
	year = {2010},
	doi = {10.1136/jnnp.2009.181743},
	publisher = {BMJ Publishing Group Ltd},
	issn = {0022-3050},
	URL = {https://jnnp.bmj.com/content/81/4/433},
	eprint = {https://jnnp.bmj.com/content/81/4/433.full.pdf},
	journal = {Journal of Neurology, Neurosurgery \& Psychiatry}
}

@article {Raffaitin2009,
    author = {Raffaitin, Christelle and Gin, Henri and Empana, Jean-Philippe and Helmer, Catherine and Berr, Claudine and Tzourio, Christophe and Portet, Florence and Dartigues, Jean-François and Alpérovitch, Annick and Barberger-Gateau, Pascale},
	title = {Metabolic syndrome and risk for incident Alzheimer's disease or vascular dementia: the Three-City Study.},
	volume = {32},
	number = {1},
	pages = {169--74},
	year = {2009},
	doi = {10.2337/dc08-0272},
	journal = {Diabetes care}
}

@article {Campbell2013,
    author = {Campbell, Noll L. and Unverzagt, Fred and LaMantia, Michael A. and Khan, Babar A. and Boustani, Malaz A.},
	title = {Risk factors for the progression of mild cognitive impairment to dementia},
	volume = {29},
	number = {4},
	pages = {873--93},
	year = {2013},
	doi = {10.1016/j.cger.2013.07.009},
	journal = {Clin Geriatr Med.}
}

@article {Ngandu2007,
    author = {Ngandu, T. and von Strauss, E. and Helkala, E-L. and Winblad, B. and Nissinen, A. and Tuomilehto, J. and Soininen, H. and Kivipelto, M. and },
	title = {Education and dementia: what lies behind the association?},
	volume = {71},
	number = {19},
	pages = {1442--50},
	year = {2007},
	doi = {10.1212/01.wnl.0000277456.29440.16},
	journal = {Neurology}
}

@article{jamaneurol,
    author = {Buckley, Rachel F. and Mormino, Elizabeth C. and Rabin, Jennifer S. and Hohman, Timothy J. and Landau, Susan and Hanseeuw, Bernard J. and Jacobs, Heidi I. L. and Papp, Kathryn V. and Amariglio, Rebecca E. and Properzi, Michael J. and Schultz, Aaron P. and Kirn, Dylan and Scott, Matthew R. and Hedden, Trey and Farrell, Michelle and Price, Julie and Chhatwal, Jasmeer and Rentz, Dorene M. and Villemagne, Victor L. and Johnson, Keith A. and Sperling, Reisa A.},
    title = "{Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults}",
    journal = {JAMA Neurology},
    volume = {76},
    number = {5},
    pages = {542-551},
    year = {2019},
    month = {05},
    issn = {2168-6149},
    doi = {10.1001/jamaneurol.2018.4693},
    url = {https://doi.org/10.1001/jamaneurol.2018.4693},
    eprint = {https://jamanetwork.com/journals/jamaneurology/articlepdf/2722842/jamaneurology\_buckley\_2019\_oi\_180107.pdf},
}

@article {Kanekiyo2014,
    author = {Kanekiyo, Takahisa and Xu, Huaxi and Bu, Guojun},
	title = {ApoE and A$\beta$ in Alzheimer's disease: accidental encounters or partners?},
	volume = {81},
	number = {4},
	pages = {740--54},
	year = {2014},
	doi = {10.1016/j.neuron.2014.01.045},
	journal = {Neuron}
}

@article{Jack2013BrainL,
  title={Brain $\beta$-amyloid load approaches a plateau},
  author={C. R. Jack and H. Wiste and T. G. Lesnick and S. D. Weigand and D. Knopman and P. Vemuri and V. S. Pankratz and M. L. Senjem and J. L. Gunter and M. Mielke and V. Lowe and B. Boeve and R. Petersen},
  journal={Neurology},
  year={2013},
  volume={80},
  pages={890 - 896}
}