\begin{table}[!htbp]
\scriptsize
\centering
\caption{Prompt--frame DSC (\%) for zero-shot segmentation across modalities and anatomical structures using single-click (1,0), multi-click (1,2), and bounding-box prompts. For each pair, the higher DSC is shown in \textbf{bold}. Color shading in the table denotes statistical significance for the better model: 
\sethlcolor{sigStrong}\hl{$p < 0.001$}, 
\sethlcolor{sigWeak}\hl{$0.001 < p < 0.05$}, 
and no shading for $p > 0.05$.}
\label{tab:prompt_frame_dsc}
\setlength{\tabcolsep}{2.5pt}
\begin{tabular}{c|c|cc|cc|cc}
\toprule
\multirow{2}{*}{\textbf{Modality}} &
\multirow{2}{*}{\textbf{Structure}} &
\multicolumn{2}{c|}{\textbf{Click (1,0)}} &
\multicolumn{2}{c|}{\textbf{Click (1,2)}} &
\multicolumn{2}{c}{\textbf{BBox}} \\
\cline{3-8}
& & \textbf{SAM 2} & \textbf{SAM 3} & \textbf{SAM 2} & \textbf{SAM 3} & \textbf{SAM 2} & \textbf{SAM 3} \\
\midrule

\multirow{19}{*}{CT}
 & Adrenal Gland (L) & 20.28 & \textbf{25.56} & 25.81 & \cellcolor{sigWeak}\textbf{37.11} & 77.04 & \textbf{78.38} \\
 & Adrenal Gland (R) & 9.60 & \textbf{10.65} & 15.56 & \textbf{20.14} & 77.45 & \textbf{79.91} \\
 & Aorta & 60.30 & \cellcolor{sigStrong}\textbf{68.14} & 65.54 & \textbf{69.59} & 84.05 & \cellcolor{sigWeak}\textbf{86.20} \\
 & Bladder & 10.33 & \cellcolor{sigStrong}\textbf{50.53} & 22.13 & \cellcolor{sigStrong}\textbf{59.97} & 84.49 & \cellcolor{sigStrong}\textbf{87.51} \\
 & Colon Tumor & 25.45 & \cellcolor{sigStrong}\textbf{44.05} & 35.21 & \cellcolor{sigStrong}\textbf{52.08} & 74.76 & \textbf{76.82} \\
 & Duodenum & 47.65 & \textbf{52.93} & 52.80 & \textbf{61.04} & 82.07 & \textbf{85.77} \\
 & Esophagus & 5.20 & \cellcolor{sigStrong}\textbf{33.93} & 20.68 & \cellcolor{sigStrong}\textbf{46.13} & 85.97 & \textbf{86.85} \\
 & Gallbladder & 24.38 & \cellcolor{sigStrong}\textbf{44.24} & 37.32 & \cellcolor{sigStrong}\textbf{52.06} & 82.68 & \cellcolor{sigWeak}\textbf{84.38} \\
 & Inferior Vena Cava & 86.25 & \cellcolor{sigWeak}\textbf{90.79} & 84.81 & \cellcolor{sigWeak}\textbf{91.24} & 91.25 & \textbf{93.63} \\
 & Kidney (L) & 51.79 & \cellcolor{sigStrong}\textbf{65.32} & 60.48 & \cellcolor{sigStrong}\textbf{67.76} & 84.48 & \cellcolor{sigStrong}\textbf{87.78} \\
 & Kidney (R) & 49.94 & \cellcolor{sigStrong}\textbf{65.13} & 61.59 & \cellcolor{sigWeak}\textbf{67.24} & 84.67 & \cellcolor{sigStrong}\textbf{88.17} \\
 & Liver & 30.62 & \cellcolor{sigStrong}\textbf{52.88} & 44.08 & \cellcolor{sigStrong}\textbf{57.99} & 78.42 & \cellcolor{sigWeak}\textbf{81.99} \\
 & Lung Tumor & 5.08 & \cellcolor{sigStrong}\textbf{19.21} & 20.12 & \cellcolor{sigWeak}\textbf{29.90} & 75.89 & \textbf{76.62} \\
 & Pancreas & 17.96 & \cellcolor{sigStrong}\textbf{36.65} & 28.60 & \cellcolor{sigStrong}\textbf{41.79} & 78.72 & \cellcolor{sigWeak}\textbf{81.22} \\
 & Pancreas Tumor & 22.01 & \cellcolor{sigStrong}\textbf{37.43} & 28.10 & \cellcolor{sigStrong}\textbf{42.81} & 85.55 & \cellcolor{sigStrong}\textbf{88.24} \\
 & Portal \& Splenic Veins & 60.85 & \cellcolor{sigWeak}\textbf{76.99} & 66.13 & \textbf{76.82} & 86.91 & \textbf{88.50} \\
 & Prostate & 9.06 & \cellcolor{sigStrong}\textbf{36.79} & 25.03 & \cellcolor{sigStrong}\textbf{47.22} & 86.01 & \textbf{87.25} \\
 & Spleen & 37.91 & \cellcolor{sigStrong}\textbf{60.77} & 54.95 & \cellcolor{sigStrong}\textbf{65.60} & 80.81 & \cellcolor{sigStrong}\textbf{85.09} \\
 & Stomach & 45.89 & \cellcolor{sigStrong}\textbf{62.82} & 56.87 & \cellcolor{sigStrong}\textbf{69.60} & 84.40 & \cellcolor{sigWeak}\textbf{87.21} \\
\midrule

\multirow{15}{*}{MR}
 & Aorta & 29.88 & \cellcolor{sigWeak}\textbf{38.59} & 37.97 & \textbf{40.79} & 83.66 & \textbf{84.97} \\
 & Bladder & 13.42 & \cellcolor{sigWeak}\textbf{86.99} & 84.28 & \textbf{87.97} & \textbf{92.42} & 90.53 \\
 & Gallbladder & 16.25 & \cellcolor{sigWeak}\textbf{26.63} & 28.62 & \textbf{33.63} & 82.00 & \textbf{83.32} \\
 & Hippocampus (Ant) & 6.89 & \cellcolor{sigStrong}\textbf{18.70} & \textbf{23.69} & 20.90 & 82.12 & \textbf{82.31} \\
 & Hippocampus (Post) & 3.16 & \cellcolor{sigStrong}\textbf{8.92} & 6.14 & \cellcolor{sigStrong}\textbf{13.37} & \textbf{82.82} & 79.41 \\
 & Kidney (L) & 41.18 & \textbf{44.71} & 48.50 & \textbf{49.75} & 81.88 & \textbf{82.86} \\
 & Kidney (R) & 40.84 & \cellcolor{sigWeak}\textbf{49.34} & 49.83 & \textbf{52.22} & 82.26 & \cellcolor{sigWeak}\textbf{84.88} \\
 & Left Atrium & 4.58 & \textbf{9.97} & 15.16 & \textbf{18.30} & 75.25 & \textbf{79.67} \\
 & Left Ventricle & 88.08 & \cellcolor{sigStrong}\textbf{95.64} & 89.10 & \cellcolor{sigStrong}\textbf{94.34} & 96.06 & \cellcolor{sigStrong}\textbf{96.75} \\
 & Liver & 19.82 & \cellcolor{sigStrong}\textbf{34.04} & 29.60 & \cellcolor{sigWeak}\textbf{39.75} & 76.87 & \textbf{78.63} \\
 & Myocardium & 36.61 & \cellcolor{sigStrong}\textbf{79.95} & 44.74 & \cellcolor{sigStrong}\textbf{72.40} & 53.80 & \cellcolor{sigStrong}\textbf{74.25} \\
 & Pancreas & 4.20 & \cellcolor{sigStrong}\textbf{17.38} & 16.13 & \cellcolor{sigWeak}\textbf{23.58} & 75.27 & \textbf{78.24} \\
 & Prostate & 13.82 & \cellcolor{sigWeak}\textbf{29.82} & 26.80 & \textbf{35.58} & 84.08 & \textbf{84.39} \\
 & Right Ventricle & 73.64 & \cellcolor{sigStrong}\textbf{86.55} & 74.90 & \cellcolor{sigStrong}\textbf{89.23} & 95.07 & \textbf{95.61} \\
 & Spleen & 20.78 & \cellcolor{sigStrong}\textbf{39.74} & 38.06 & \cellcolor{sigStrong}\textbf{49.25} & 77.78 & \textbf{79.50} \\
\midrule

\multirow{8}{*}{US}
 & Carotid Artery (L) & 0.38 & \textbf{0.68} & \textbf{3.62} & 1.61 & \textbf{64.05} & 57.98 \\
 & Carotid Artery (R) & 0.18 & \textbf{1.46} & \cellcolor{sigWeak}\textbf{14.53} & 3.30 & \textbf{61.06} & 60.97 \\
 & Jugular Vein (L) & 1.14 & \textbf{2.65} & \textbf{6.74} & 2.93 & \textbf{58.41} & 55.61 \\
 & Jugular Vein (R) & 0.40 & \textbf{1.63} & \textbf{6.99} & 2.50 & \textbf{58.32} & 54.97 \\
 & Left Atrium & 17.61 & \cellcolor{sigStrong}\textbf{25.31} & 47.37 & \cellcolor{sigStrong}\textbf{60.30} & 76.99 & \cellcolor{sigStrong}\textbf{82.61} \\
 & LV Endocardium & 31.73 & \cellcolor{sigStrong}\textbf{70.46} & 69.49 & \cellcolor{sigWeak}\textbf{73.01} & \textbf{86.77} & 86.16 \\
 & LV Epicardium & 23.98 & \cellcolor{sigStrong}\textbf{27.65} & \cellcolor{sigStrong}\textbf{30.73} & 26.04 & 34.15 & \textbf{34.93} \\
 & Thyroid & 0.99 & \textbf{3.89} & \textbf{5.88} & 3.70 & \textbf{67.19} & 65.14 \\
\midrule

\multirow{12}{*}{Endoscopy}
 & Abdominal Wall & 58.07 & \textbf{72.06} & 77.34 & \textbf{80.86} & \textbf{87.33} & 87.24 \\
 & Blood & 3.06 & \textbf{3.08} & 42.03 & \textbf{63.01} & \textbf{73.81} & 72.91 \\
 & Connective Tissue & \textbf{66.34} & 54.60 & \textbf{68.74} & 67.61 & 85.01 & \textbf{88.95} \\
 & Cystic Duct & 30.50 & \textbf{32.92} & \textbf{29.70} & 13.45 & 41.92 & \textbf{48.84} \\
 & Fat & 62.33 & \textbf{74.23} & \textbf{72.84} & 62.25 & \textbf{53.74} & 52.80 \\
 & Gallbladder & 73.32 & \textbf{83.38} & 82.24 & \textbf{83.48} & 88.38 & \textbf{88.44} \\
 & GI Tract & 53.26 & \textbf{79.72} & 80.53 & \textbf{86.75} & 92.02 & \textbf{93.13} \\
 & Grasper & 81.52 & \textbf{90.12} & \textbf{90.30} & 88.98 & \textbf{87.00} & 86.53 \\
 & Hepatic Vein & \textbf{87.78} & 85.87 & \textbf{88.03} & 86.91 & \textbf{88.74} & 87.64 \\
 & L-Hook Electrocautery & \textbf{73.67} & 72.20 & \textbf{74.06} & 71.93 & 89.42 & \textbf{90.96} \\
 & Liver & 55.80 & \textbf{66.08} & 63.87 & \textbf{67.55} & 72.76 & \textbf{73.40} \\
 & Liver Ligament & \textbf{98.38} & 98.25 & \textbf{98.29} & 95.66 & \textbf{98.55} & 98.52 \\
\bottomrule
\end{tabular}
\end{table}
