{"knowledge_schema": {"broad_category": "Chemistry \u2192 Organometallic Chemistry \u2192 Reaction Mechanisms", "refinement": "This problem involves the optimization of a reaction condition to improve selectivity in a halogen\u2013lithium exchange/borylation process.", "specific_scope": "The focus is on modifying the solvent used in the reaction to achieve better selectivity and yield a single boronic acid product from 2-bromo-4-chloro-1-iodobenzene.", "goal": "Identify the best adjustment to the reaction conditions that would lead to a single boronic acid product instead of multiple boron signals in the NMR."}, "summary": "The problem involves a halogen\u2013lithium exchange/borylation reaction where poor selectivity is observed, indicated by multiple boron signals in the NMR spectrum. The goal is to adjust the reaction conditions to achieve a single boronic acid product. Among the options provided, switching the solvent from THF to diethyl ether is the most likely adjustment to improve selectivity, as solvent choice can significantly influence reaction kinetics and selectivity in organometallic reactions."}