{"knowledge_schema": {"broad_category": "Biochemistry \u2192 Protein Structure \u2192 Oligomeric State Determination", "refinement": "This problem involves analyzing a coiled-coil protein sequence to determine its oligomeric state based on structural interactions and packing efficiency.", "specific_scope": "The focus is on the specific coiled-coil sequence provided, examining its potential to form oligomers through knobs-into-holes interactions.", "goal": "Identify the most likely oligomeric state of the protein based on the sequence and principles of coiled-coil structure."}, "summary": "The problem requires determining the oligomeric state of a given coiled-coil protein sequence by analyzing its structural features and interactions. Coiled-coil proteins typically form oligomers through specific packing interactions, known as knobs-into-holes, which influence their stability and efficiency. By examining the sequence GEIAQSLKEIAKSLKEIAWSLKEIAQSLKG, we can infer the most likely oligomeric state based on these interactions. The goal is to select the correct number of subunits that would optimally pack together, considering the provided candidates."}