{"knowledge_schema": {"broad_category": "Biology \u2192 Developmental Biology \u2192 Insect Physiology", "refinement": "This problem focuses on the nutritional requirements of Drosophila for proper development and survival, particularly concerning the synthesis of the molting hormone Ecdysone from sterol precursors.", "specific_scope": "The task involves predicting the developmental outcomes of Drosophila larvae based on their diet and the diet of their mothers, specifically in relation to cholesterol and cholestanol availability.", "goal": "Determine the developmental outcomes of Drosophila based on maternal diet and larval diet in terms of survival and eclosion to adulthood."}, "summary": "This problem examines the impact of dietary sterols on the development of Drosophila, particularly focusing on the effects of cholesterol and cholestanol. The task is to predict the outcomes for Drosophila larvae based on their diet and the diet of their mothers. The first scenario involves larvae fed 250mg/L cholestanol from mothers reared on cholesterol, while the second scenario involves larvae fed a combination of cholestanol and cholesterol from mothers reared on cholestanol. The goal is to assess whether the larvae will survive, develop normally, or fail to eclose to adulthood based on the nutritional context provided."}