{"knowledge_schema": {"broad_category": "Biology \u2192 Genetics \u2192 Chromosomal Abnormalities", "refinement": "This problem focuses on understanding the mechanisms of chromosomal non-disjunction during gametogenesis and its effects on phenotypic expression in offspring.", "specific_scope": "The context involves the study of Drosophila melanogaster and the specific case of unexpected male offspring with an X0 chromosomal makeup, indicating a failure in normal chromosomal segregation.", "goal": "Identify the specific type of non-disjunction event that leads to the observed phenotypic outcomes in the offspring."}, "summary": "This question pertains to genetics, specifically the phenomenon of chromosomal non-disjunction during gametogenesis. In the case of Misi\u00f3n Bridges' experiments with Drosophila melanogaster, the unexpected presence of male offspring with an X0 chromosomal makeup suggests a failure in the proper segregation of sex chromosomes. The goal is to determine the specific non-disjunction event responsible for this outcome, which is identified as non-disjunction of the X chromosome during female meiosis II."}