{"knowledge_schema": {"broad_category": "Chemistry \u2192 Organic Chemistry \u2192 Stereochemistry and Reaction Mechanisms", "refinement": "This problem involves the stereochemical outcomes of reactions involving alkenes and the analysis of products using chromatographic techniques.", "specific_scope": "The focus is on the reactions of (E)-hex-3-ene and (Z)-hex-3-ene with mCPBA, leading to the formation of epoxides and their subsequent acid-catalyzed ring-opening, and how these products are resolved in standard and chiral HPLC.", "goal": "To determine the number of peaks observed in standard and chiral HPLC for the products of the reactions, indicating the presence of different stereoisomers."}, "summary": "In this problem, we analyze the reactions of (E)-hex-3-ene and (Z)-hex-3-ene with mCPBA, which leads to the formation of epoxides. Upon treatment with aqueous acid, these epoxides undergo ring-opening, resulting in different stereochemical products. In standard HPLC, the chemist observes 2 peaks due to the formation of two distinct products from each alkene. However, in chiral HPLC, the resolution of stereoisomers allows for the observation of 3 peaks, reflecting the presence of enantiomers and diastereomers. Thus, the correct observation is 2 peaks in standard HPLC and 3 peaks in chiral HPLC."}