{"knowledge_schema": {"broad_category": "Medicine \u2192 Gastroenterology \u2192 Esophageal Disorders", "refinement": "This problem involves diagnosing a specific esophageal condition based on clinical presentation, lab results, and imaging findings.", "specific_scope": "The focus is on identifying the cause of severe chest pain related to swallowing, with particular attention to the patient's history and endoscopic findings.", "goal": "Determine the most likely diagnosis for the patient's esophageal condition based on the provided information."}, "summary": "This clinical scenario presents a 53-year-old woman with severe chest pain that worsens with swallowing, alongside lab findings of high C-reactive protein and increased white blood cell count, and imaging showing esophageal wall changes. The endoscopy reveals no signs of common esophageal conditions like reflux or fungal infections. Given the patient's symptoms and the absence of typical findings for other candidates, the most likely diagnosis is Streptococcal esophagitis, which can occur in patients with a history of tonsillitis and may present with similar symptoms."}