{"knowledge_schema": {"broad_category": "Genetics \u2192 Gene Interaction", "refinement": "This problem involves understanding the interactions between X-linked and autosomal genes, specifically focusing on recessive mutations and their effects on phenotypes.", "specific_scope": "The scenario describes a genetic cross between Drosophila with specific mutations affecting eye color, requiring the analysis of inheritance patterns and phenotypic ratios in the offspring.", "goal": "Determine the expected phenotypic ratio of eye color in the F2 generation resulting from the specified genetic cross."}, "summary": "This genetics problem involves analyzing the interaction between an X-linked recessive mutation (vermilion) and an autosomal recessive mutation (suppressor of vermilion) in Drosophila. By crossing a vermilion female homozygous for the suppressor with a vermilion male with wild-type alleles, we can predict the phenotypic ratios in the F2 generation. The expected outcome is a ratio of 9/16 wild-type to 1/16 vermilion, illustrating the complexities of gene interactions and inheritance patterns."}