{"knowledge_schema": {"broad_category": "Medicine \u2192 Pharmacology \u2192 Antibiotic Therapy", "refinement": "This problem involves selecting appropriate antibiotics based on susceptibility testing results for a patient with a severe skin infection.", "specific_scope": "The focus is on identifying which antibiotics from a list of candidates are effective against the patient's infection based on culture results indicating resistance and susceptibility.", "goal": "Narrow down the antibiotic regimen to include only those that are effective (susceptible) against the identified pathogens."}, "summary": "In this scenario, the goal is to select effective antibiotics for a patient with a severe skin infection based on culture results showing resistance and susceptibility. The antibiotics that are susceptible (S) for this patient include Clindamycin, Vancomycin, Linezolid, and Trimethoprim/Sulfamethoxazole, while Tetracycline is indicated as intermediate (I). The task is to identify which of the candidate options contain only those antibiotics that are effective against the infection. The reasonable treatment options based on the culture results are those that include Clindamycin, Vancomycin, and Linezolid."}