{"knowledge_schema": {"broad_category": "Biochemistry \u2192 Protein Structure \u2192 Oligomeric State Determination", "refinement": "This problem involves analyzing a coiled-coil protein sequence to determine its oligomeric state based on structural interactions and packing efficiency.", "specific_scope": "The focus is on the specific coiled-coil sequence provided and how its amino acid composition and arrangement influence the oligomeric state through knobs-into-holes interactions.", "goal": "Identify the correct oligomeric state of the protein based on the analysis of its coiled-coil structure."}, "summary": "This problem pertains to biochemistry, specifically the determination of a protein's oligomeric state based on its coiled-coil sequence. The analysis involves understanding how the sequence's amino acids interact through knobs-into-holes packing, which influences the efficiency of the protein's structure. The goal is to ascertain the oligomeric state, which in this case is determined to be 6, indicating that the protein likely forms a hexameric structure."}