Based on prior knowledge, it is difficult to determine the relationship between the sex of the patient and the presence of heart disease. Heart disease can occur in both males and females. Therefore, it is difficult to predict whether the patient has heart disease based solely on the sex of the patient. 

However, I will still create a dictionary, including all possible values of the feature 'Sex' for each target class:

```json
{
	"no": ["M", "F"],
	"yes": ["M", "F"]
}
```

This dictionary includes all potential values of the feature 'Sex' for both target classes, regardless of the predictability.