Evolutionary-Progressive Method for Multiple Sequence Alignment

Pawel Kupis, Jacek Mandziuk

Abstract: In this paper a new evolutionary-progressive method for multiple sequence alignment (MSA) is proposed. The method efficiently combines flexibility of evolutionary approach with speed and accuracy of progressive technique. Both stages of introduced hybrid method are described in detail. The results of comparison with several well-known methods show that proposed evolutionary-progressive method is an interesting alternative for purely genetic and purely progressive approaches