Exploring biological challenges in building a thinking machine

Christ Devia, Camilo Jara Do Nascimento, Samuel Madariaga, Pedro Maldonado, Catalina Murúa, Rodrigo C. Vergara

Abstract: Highlights•Interdisciplinary advances between neuroscience and AI are bidirectional.•Canonical microcircuits offer insights into more biologically plausible ANNs.•ANNs and biological systems diverge in goal orientation, learning rules, and physical constraints.•Brain circuits need clearer input–output definitions, posing challenges for modeling.