DTome: a web-based tool for drug-target interactome construction

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Jingchun Sun, Yonghui Wu, Hua Xu, Zhongming Zhao

Published: 2012, Last Modified: 08 Jan 2026BMC Bioinform. 2012EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: Understanding drug bioactivities is crucial for early-stage drug discovery, toxicology studies and clinical trials. Network pharmacology is a promising approach to better understand the molecular mechanisms of drug bioactivities. With a dramatic increase of rich data sources that document drugs' structural, chemical, and biological activities, it is necessary to develop an automated tool to construct a drug-target network for candidate drugs, thus facilitating the drug discovery process.