Guideline-informed reinforcement learning for mechanical ventilation in critical care

Floris den Hengst, Martijn Otten, Paul W. G. Elbers, Frank van Harmelen, Vincent François-Lavet, Mark Hoogendoorn

Abstract: Highlights•Reinforcement learning based on observational data and existing knowledge.•Treatment advice and physiological knowledge in guidelines are injected into learner.•Ventilation case study indicates adherence to guidelines, clinician outperformance.