Machine learning model for predicting excessive muscle loss during neoadjuvant chemoradiotherapy in oesophageal cancer

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Han Gyul Yoon, Dongryul Oh, Jae Myoung Noh, Won Kyung Cho, Jong‐Mu Sun, Hong Kwan Kim, Jae Ill Zo, Young Mog Shim, Kyunga Kim

Published: 01 Oct 2021, Last Modified: 12 Dec 2025Journal of Cachexia, Sarcopenia and MuscleEveryoneRevisionsCC BY-SA 4.0
Abstract: Excessive skeletal muscle loss during neoadjuvant concurrent chemoradiotherapy (NACRT) is significantly related to survival outcomes of oesophageal cancer. However, the conventional method for measuring skeletal muscle mass requires computed tomography (CT) images, and the calculation process is labour-intensive. In this study, we built machine-learning models to predict excessive skeletal muscle loss, using only body mass index data and blood laboratory test results.