HACA3: A unified approach for multi-site MR image harmonization

Lianrui Zuo, Yihao Liu, Yuan Xue, Blake E. Dewey, Samuel W. Remedios, Savannah Hays, Murat Bilgel, Ellen M. Mowry, Scott D. Newsome, Peter A. Calabresi, Susan M. Resnick, Jerry L. Prince, Aaron Carass

Abstract: Highlights•A unified harmonization approach that disentangles contrast and anatomy, while respecting inherent anatomical difference between MR contrasts.•A novel attention mechanism optimally processes anatomical information based on image contrast and artifacts.•Extensive evaluations on 21 imaging sites with diverse acquisition parameters and image quality.