Wavelet-Based Feature Extraction for Microarray Data Classification

Shutao Li, Chen Liao, James T. Kwok

Abstract: Microarray data typically have thousands of genes, and thus feature extraction is a critical problem for accurate cancer classification. In this paper, a feature extraction method based on the discrete wavelet transform (DWT) is proposed. The approximation coefficients of DWT, together with some useful features from the high-frequency coefficients selected by the maximum modulus method, are used as features. The combined coefficients are then forwarded to a SVM classifier. Experiments are performed on two standard benchmark data sets: ALL/AML Leukemia and Colon tumor. Experimental results show that the proposed method can achieve state-of-the-art performance on cancer classification.