A Data-Adaptive Approach to cDNA Microarray Image Enhancement

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Rastislav Lukac, Konstantinos N. Plataniotis, Bogdan Smolka, Anastasios N. Venetsanopoulos

Published: 2005, Last Modified: 27 Sept 2024International Conference on Computational Science (2) 2005EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: A data-adaptive approach for cDNA microarray image enhancement is presented. Through the weighting coefficients adaptively determined from local microarray image statistics, the proposed technique tunes the overall filter’s detail-preserving and noise-attenuating characteristics and uses both the spatial and spectral correlation of the cDNA image during processing. Noise removal is performed by tuning a membership function which utilizes the aggregated absolute differences between the cDNA microarray inputs localized within a processing window sliding over the image.