Evolving pathway activation from cancer gene expression data using nature-inspired ensemble optimization

Xubin Wang, Yunhe Wang, Zhiqiang Ma, Ka-Chun Wong, Xiangtao Li

Abstract: Highlights•HSNOE can mitigate the effects of data skew when training the model.•A nature-inspired feature selection method is used to identify informative features.•HSNOE combines a nature-inspired optimization method to realize ensemble.•A case study was conducted to show the generalization capabilities of HSNOE.