Engineering modular bacteriophage genomes for targeted bacterial elimination

Published: 06 Mar 2025, Last Modified: 26 Apr 2025GEMEveryoneRevisionsBibTeXCC BY 4.0
Track: Biology: datasets and/or experimental results
Nature Biotechnology: Yes
Keywords: bacteriophage, protein design, antimicrobial resistance
TL;DR: We introduce a new experimental method that is augmented by computation to generate phage genomic scaffolds that can be used as generalizable starting points for therapeutic bacteriophages.
Abstract: Please see attached pdf.
Anonymization: This submission has been anonymized for double-blind review via the removal of identifying information such as names, affiliations, and identifying URLs.
Presenter: ~Sriharshita_Musunuri1
Format: Maybe: the presenting author will attend in person, contingent on other factors that still need to be determined (e.g., visa, funding).
Funding: Yes, the presenting author of this submission falls under ICLR’s funding aims, and funding would significantly impact their ability to attend the workshop in person.
Submission Number: 111
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