From Model to Molecule: Rapid Discovery of Potent CDK2 Inhibitors Using Boltz-2

Sven M. Papidocha, Stuart R. Green, Varinia Bernales, Alan Aspuru-Guzik

Submission Type: I want my submission to be considered for both oral and poster presentation.

Keywords: Drug Discovery, Structure-Based Drug Design, Cyclin-Dependent Kinase, Artificial Intelligence

TL;DR: Boltz-2 enables a closed-loop computational–experimental workflow that translates large-scale virtual screening into experimentally validated CDK2 inhibitors.

Confirmation Of Submission Requirements: I submit an abstract. It uses the template provided on the submission page and is no longer than 2 pages.

Submission Number: 382