Efficient Computational Methods for Strongly Coupled Cardiac Electromechanics

Sander Land, Steven A. Niederer, Nicolas Smith

Abstract: Strongly coupled cardiac electromechanical models can further our understanding of the relative importance of feedback mechanisms in the heart, but computational challenges currently remain a major obstacle, which limit their widespread use. To address this issue, we present a set of efficient computational methods including an efficient adaptive cell model integration scheme and a solution method for the monodomain equations that maintains high conduction velocity for time steps greater than 0.1 ms. We also present a novel method for increasing the efficiency of simulating electromechanical coupling, which shows a significant reduction in computational cost of the mechanical component on a personalized left ventricular geometry with an active contraction cell model reparametrized for human cells.

External IDs:dblp:journals/tbe/LandNS12