Acoustical features as knee health biomarkers: A critical analysis

Christodoulos Kechris, Jérôme Thevenot, Tomás Teijeiro, Vincent A. Stadelmann, Nicola A. Maffiuletti, David Atienza

Abstract: Highlights•Classification accuracy alone cannot robustly guarantee an association between acoustic features and health conditions.•Causal investigation on the audio features is imperative to claim them as biomarkers•Thorough manual audio–visual inspection helps in the causal attribution investigation.•The consistency of experimental conditions is critical to attribute audio components to physical processes.