Topographic organization of the cerebral cortex and brain cartography

Simon B. Eickhoff, R. Todd Constable, B. T. Thomas Yeo

Abstract: Highlights•The concept of cortical areas is fundamental to systems neuroscience.•Cortical areas should differentiate themselves through distinct structure, functionand connectivity.•This classical definitions are not trivially translated to human neuroimaging.•We here propose a reformulation of this concept based on increasing dissimilaritybetween neurobiological atoms along multi-dimensional features.•Each individual parcellation represents a specific view on this organization.