SPRING: a kinetic interface for visualizing high dimensional single-cell expression data

Caleb Weinreb, Samuel L. Wolock, Allon M. Klein

Abstract: Single-cell gene expression profiling technologies can map the cell states in a tissue or organism. As these technologies become more common, there is a need for computational tools to explore the data they produce. In particular, visualizing continuous gene expression topologies can be improved, since current tools tend to fragment gene expression continua or capture only limited features of complex population topologies.