FocusMR: An Attention-Based Single-Cell Mendelian Randomization Framework to Map Cellular Contexts at Candidate Genes

Martin Meinel, Jan P. Engelmann, Michael Patrick Menden, Theofanis Karaletsos, Francesco Paolo Casale

Published: 23 Sept 2025, Last Modified: 18 Oct 2025AI4D3 2025 OralEveryoneRevisionsBibTeXCC BY 4.0
Keywords: Mendelian Randomization, Multiple instance learning, Early-stage target discovery, Single-cell genetics
TL;DR: FocusMR provides a principled approach to map genetic risk to specific cellular contexts, supporting early-stage target discovery.
Submission Number: 45