Computational Systems Biology Platforms (Computergestützte Systembiologieplattformen)

Ivayla Vacheva, Roland Eils

Abstract: Numerous software platforms in Computational Systems Biology have been developed in the past decade. Each program has its own strengths but their functionality often overlaps significantly. In this article, we review numerous aspects related to the functionality and infrastructure of existing platforms in the context of a selected set of tools. We discuss the biological problems that can be solved with these tools and point out directions for future research in the field.