Abstract: Highlights•2D and 3D models face accuracy and efficiency challenges in segmenting 2.5D images.•We proposed CSA-Net, a 2.5D model designed for the segmentation of 2.5D images.•CSA-Net uses cross-slice attention to effectively capture inter-slice correlations.•CSA-Net outperformed leading 2D, 2.5D, and 3D models across three 2.5D datasets.
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