Real-time functional brain mapping using electrocorticography

Kai J. Miller, Marcel den Nijs, Pradeep Shenoy, John W. Miller, Rajesh P. N. Rao, Jeffrey G. Ojemann

Abstract: We demonstrate the feasibility of real-time cortical mapping from arrays of subdural electrodes using the electrocorticographic signal power in the higher spectral frequencies (76–200 Hz, or “χ-index”). Hand area was mapped offline in eight individuals using brief baseline and hand-movement measurements. In one patient, hand sensorimotor cortex was identified online during a handshake. We propose that this high-frequency component of the electrocorticogram provides a generic, reliable, clinically useful correlate of local cortical function.