øperatorname cIDIR: Conditioned Implicit Neural Representation for Regularized Deformable Image Registration

Sidaty El Hadramy, Oumeymah Cherkaoui, Philippe C. Cattin

Abstract: Regularization is essential in deformable image registration (DIR) to ensure that the estimated Deformation Vector Field (DVF) remains smooth, physically plausible, and anatomically consistent. However, fine-tuning regularization parameters in learning-based DIR frameworks is computationally expensive, often requiring multiple training iterations. To address this, we propose \(\operatorname {cIDIR}\), a novel DIR framework based on Implicit Neural Representations (INRs) that conditions the registration process on regularization hyperparameters. Unlike conventional methods that require retraining for each regularization hyperparameter setting, \(\operatorname {cIDIR}\) is trained over a prior distribution of these hyperparameters, then optimized over the regularization hyperparameters by using the segmentations masks as an observation. Additionally, \(\operatorname {cIDIR}\) models a continuous and differentiable DVF, enabling seamless integration of advanced regularization techniques via automatic differentiation. Evaluated on the DIR-LAB [5, 6] dataset, \(\operatorname {cIDIR}\) achieves high accuracy and robustness across the dataset.

External IDs:dblp:conf/miccai/HadramyCC25