Semantic search for 100M+ galaxy images using AI-generated captions

Published: 24 Sept 2025, Last Modified: 26 Dec 2025NeurIPS2025-AI4Science SpotlightEveryoneRevisionsBibTeXCC BY 4.0
Additional Submission Instructions: For the camera-ready version, please include the author names and affiliations, funding disclosures, and acknowledgements.
Track: Track 1: Original Research/Position/Education/Attention Track
Keywords: vision-language models, scientific image retrieval, semantic search, contrastive learning, automated discovery, astrophysics
TL;DR: We show that Vision-Language Models can generate synthetic annotations for scientific images, enabling semantic search over 140 million astronomical images and demonstrating a scalable framework for making large scientific image archives searchable.
Abstract: Finding scientifically interesting phenomena through slow, manual labeling campaigns severely limits our ability to explore the billions of galaxy images produced by telescopes. In this work, we develop a pipeline to create a semantic search engine from completely unlabeled image data. Our method leverages Vision-Language Models (VLMs) to generate descriptions for galaxy images, then contrastively aligns a pre-trained multimodal astronomy foundation model with these embedded descriptions to produce searchable embeddings at scale. We find that current VLMs provide descriptions that are sufficiently informative to train a semantic search model that outperforms direct image similarity search. Our model, AION-Search, achieves state-of-the-art zero-shot performance on finding rare phenomena despite training on randomly selected images with no deliberate curation for rare cases. Furthermore, we introduce a VLM-based re-ranking method that nearly doubles the recall for our most challenging targets in the top-100 results. For the first time, AION-Search enables flexible semantic search across 140 million galaxy images, enabling discovery from previously infeasible searches. More broadly, our work provides an approach for making large, unlabeled scientific image archives semantically searchable, expanding data exploration capabilities in fields from Earth observation to microscopy. The code, data, and app are publicly available at https://github.com/NolanKoblischke/AION-Search
Submission Number: 299
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