Hierarchical rhythmic propagation of corticothalamic interactions for consciousness: A computational study

Qian Zhang, Han Lu, Jihang Wang, Taoyi Yang, Weida Bi, Yi Zeng, Buwei Yu

Abstract: Highlights•A neural network is established to simulate propofol with millisecond resolution.•The structural basis of anteriorization is assessed in clinical anesthesia.•Heterogeneous brain connectivity explains hierarchical rhythm propagation.•This model enables brain simulation constrained by inter-areal directed connections.