Combining Multiple Deep Features for Glaucoma Classification

Annan Li, Yunhong Wang, Jun Cheng, Jiang Liu

Abstract: Glaucoma is one of the leading cause of blindness. Although there is still no cure, early detection can prevent serious vision loss. Therefore automated glaucoma detection/classification is an important issue. In the past decade, segmentation based approach such as those based on cup-to-disc-ratio are popular, but single indicator limit its performance. Recently, convolutional neural network based image classification approaches that can use more image cues achieve good performance. In this paper, we propose a new glaucoma classification by combining multiple features extracted by different convolutional neural networks. Its effectiveness is clearly demonstrated on the publicly available Origa [1] dataset. It achieves an area under the receiver operating characteristic curve of 0.8483, which better than the 0.838 given by on manual marked cup-to-disc-ratio. To our knowledge, it is the first approach surpass human in glaucoma classification.