Aperiodic brain activity and response to anesthesia vary in disorders of consciousness

Charlotte Maschke, Catherine Duclos, Adrian M. Owen, Karim Jerbi, Stefanie Blain-Moraes

Abstract: Highlights•Aperiodic EEG, but not oscillation, correlates with level of consciousness.•Anesthesia steepens the EEG spectral slope across disorders of consciousness.•Changes in EEG spectral slope reflect pre-anesthetic level of responsiveness.•Changes in the aperiodic EEG accompany loss of signal complexity and criticality.