A Knowledge Gradient Policy for Sequencing Experiments to Identify the Structure of RNA Molecules Using a Sparse Additive Belief Model

Yan Li, Kristofer G. Reyes, Jorge Vazquez-Anderson, Yingfei Wang, Lydia M. Contreras, Warren B. Powell

Abstract: We present a sparse knowledge gradient (SpKG) algorithm for adaptively selecting the targeted regions within a large RNA molecule to identify which regions are most amenable to interactions with ot...