LensePro: label noise-tolerant prototype-based network for improving cancer detection in prostate ultrasound with limited annotations

Minh Nguyen Nhat To, Fahimeh Fooladgar, Paul Wilson, Mohamed Harmanani, Mahdi Gilany, Samira Sojoudi, Amoon Jamzad, Silvia Chang, Peter Black, Parvin Mousavi, Purang Abolmaesumi

Published: 10 Apr 2024, Last Modified: 26 Feb 2026International Journal of Computer Assisted Radiology and SurgeryEveryoneRevisionsCC BY-SA 4.0
Abstract: The standard of care for prostate cancer (PCa) diagnosis is the histopathological analysis of tissue samples obtained via transrectal ultrasound (TRUS) guided biopsy. Models built with deep neural networks (DNNs) hold the potential for direct PCa detection from TRUS, which allows targeted biopsy and subsequently enhances outcomes. Yet, there are ongoing challenges with training robust models, stemming from issues such as noisy labels, out-of-distribution (OOD) data, and limited labeled data.
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