MERIDA: a novel Boolean logic-based integer linear program for personalized cancer therapy

Kerstin Lenhof, Nico Gerstner, Tim Kehl, Lea Eckhart, Lara Schneider, Hans-Peter Lenhof

Abstract: A major goal of personalized medicine in oncology is the optimization of treatment strategies given measurements of the genetic and molecular profiles of cancer cells. To further our knowledge on drug sensitivity, machine learning techniques are commonly applied to cancer cell line panels.