Preemptive optimization of a clinical antibody for broad neutralization of SARS-CoV-2 variants and robustness against viral escape

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Kevin M Tuffy, Vancheswaran Gopalakrishnan, Chang Liu, Juthathip Mongkolsapaya, Ka Yin Kwong, Pavlo Gilchuk, Christopher Morehouse, Amy Nguyen, Jagadish Beloor, Gustavo Hernan Kijak, Thomas Anthony Desautels, Svetlana Hopkins, Shivshankar Sundaram, Fangqiang Zhu, Gavin Robert Screaton, Joseph Richard Francica, Yi Zhang, Andrew Dippel, Christopher George Earnhart, Saravanan Rajan et al. (25 additional authors not shown)

Published: 28 Mar 2025, Last Modified: 03 Apr 2026Science AdvancesEveryoneRevisionsCC BY-SA 4.0