Shriram Chennakesavalu

Researcher, Genentech

Joined

May 2024

Names

Shriram Chennakesavalu (Preferred)

Emails

****@stanford.edu (Confirmed)

,

****@gmail.com (Confirmed)

,

****@gene.com (Confirmed)

Personal Links

Career & Education History

Researcher

Genentech (gene.com)

2024 – Present

PhD student

Chemistry, Stanford University (stanford.edu)

2020 – 2024

Advisors, Relations & Conflicts

PhD Advisor

Grant M. Rotskoff

2020 – 2025

Expertise

Generative Models

,

Biophysics

,

Statistical Mechanics

Present

Publications

Evaluating the Progression of Large Language Model Capabilities for Small-Molecule Drug Design
Shriram Chennakesavalu, Kirill Shmilovich, Hayley Weir, Colin A Grambow, John Bradshaw, Patricia Suriana, Chen Cheng, Kangway V. Chuang
- GenBio 2026 Poster
- Readers: Everyone
Evaluating the Progression of Large Language Model Capabilities for Small-Molecule Drug Design
Shriram Chennakesavalu, Kirill Shmilovich, Hayley Weir, Colin A Grambow, John Bradshaw, Patricia Suriana, Chen Cheng, Kangway V. Chuang
- ICML2026-AI4Science Poster
- Readers: Everyone
Efficient, Few-shot Directed Evolution with Energy Rank Alignment
Sebastian Ibarraran, Shriram Chennakesavalu, Frank Hu, Grant M. Rotskoff
- GEM 2026
- Readers: Everyone
Aligning Transformers with Continuous Feedback via Energy Rank Alignment
Shriram Chennakesavalu, Frank Hu, Sebastian Ibarraran, Grant M. Rotskoff
- NeurIPS 2025 poster
- Readers: Everyone
Aligning Chemical and Protein Language Models with Continuous Feedback using Energy Rank Alignment
Shriram Chennakesavalu, Frank Hu, Sebastian Ibarraran, Grant M. Rotskoff
- GEM
- Readers: Everyone
Energy Rank Alignment: Using Preference Optimization to Search Chemical Space at Scale
Shriram Chennakesavalu, Frank Hu, Sebastian Ibarraran, Grant M. Rotskoff
- Submitted to NeurIPS 2024
- Readers: Everyone

Co-Authors