Learning Registration Models with Differentiable Gauss-Newton Optimisation

Mattias P Heinrich

• Keywords: Learn to optimise, medical image registration, second order descent
• TL;DR: Learn to predict displacement Jacobian and residual vectors for improving second-order least-squares solution for image registration.
• Abstract: We propose to capture large deformations in few iterations by learning a registration model with differentiable Gauss-Newton and compact CNNs that predict displacement gradients and a suitable residual function. By incorporating a sparse Laplacian regulariser, structural / semantic representations and weak label-supervision we achieve state-of-the-art performance for abdominal CT registration.
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• Paper Type: novel methodological ideas without extensive validation
• Primary Subject Area: Image Registration
• Secondary Subject Area: Meta Learning
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