Abstract: Highlights•SynthRAD2023 is the first large multi-center CT synthesis challenge for radiotherapy.•SynthRAD offers benchmark datasets and methods to evaluate image synthesis.•The challenge focused on MRI- or CBCT-to-CT synthesis for pelvis and brain.•Large participation was obtained, with 22 (MRI-to-CT) and 17 (CBCT-to-CT) teams.•Top-performing teams achieved excellent image similarity and dose accuracy.
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