The NCI Imaging Data Commons as a platform for reproducible research in computational pathology

Daniela P. Schacherer, Markus D. Herrmann, David A. Clunie, Henning Höfener, William Clifford, William J. R. Longabaugh, Steven D. Pieper, Ron Kikinis, Andrey Fedorov, André Homeyer

Abstract: Highlights•The Imaging Data Commons (IDC) is a new repository of FAIR cancer image collections.•Introduction to using the IDC for reproducible research in computational pathology.•The IDC and cloud-based machine learning services facilitate reproducibility in complementary ways.•Evaluation results indicate a practical reproducibility limit.•Categorization of key reproducibility challenges of computational pathology studies.