Keywords: breast MRI, segmentation, 2D U-Net, BPE, BI-RADS, breast cancer
TL;DR: Automatic Background Parenchymal Enhancement segmentation from Breast MRI images for standarized classification according to BI-RADS.
Abstract: Contrast-enhanced breast MRI plays a crucial role in the care of women at high risk of developing breast cancer. Contrast agent uptake in the breast tissue, i.e., Background Parenchymal Enhancement (BPE), may be an indicator of a higher risk of developing breast cancer and may limit the detectability of lesions. Not only the degree, but also the area of enhancement are elements of importance in the decision-making process in each case. However, they rely on the visual assessment of the reader and thus suffer from poor reliability and reproducibility. In this study, we have developed and evaluated a deep learning (DL) multiclass algorithm for segmentation of both: the BPE area and the non-enhancing tissue. For training, validation, and testing 3441 slices were used. The mean Dice Similarity Coefficient (DSCmean) for the test set amounted to 0.76. Our results show that accurate BPE segmentation is feasible with DL for all classes of enhancement. Such an algorithm may be implemented as part of a pipeline for precise BPE classification or may find direct clinical application in the management of high-risk patients in breast MRI.
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Paper Type: novel methodological ideas without extensive validation
Primary Subject Area: Segmentation
Secondary Subject Area: Application: Radiology
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