Impact of detecting clinical trial elements in exploration of COVID-19 literature

Simon Suster, Karin M. Verspoor, Timothy Baldwin, Jey Han Lau, Antonio Jimeno-Yepes, David Martinez Iraola, Yulia Otmakhova

Abstract: The COVID-19 pandemic has driven ever-greater demand for tools which enable efficient exploration of biomedical literature. Although semi-structured information resulting from concept recognition and detection of the defining elements of clinical trials (e.g. PICO criteria) has been commonly used to support literature search, the contributions of this abstraction remain poorly understood. In this study, we compare the results retrieved by a standard search engine with those filtered using clinically-relevant concepts and their relations. Most importantly, with an analysis based on the TREC-COVID dataset, we find that the relational concept selection filters the original retrieved collection in a way that decreases the proportion of unjudged documents and increases the precision, which means that the user is likely to be exposed to a larger number of relevant documents.