Multiscale and global-local U-Net for protein-protein interaction site prediction

Dangguo Shao, Yuyang Zou, Lei Ma, Sanli Yi

Abstract: Highlights•Three pooling and Three unpooling layers capture multi-scale protein structural information.•Fused Transformer, GCN and GAT capture multi-scale global and local features.•U-Net processing followed by a second pass enables deeper feature extraction.•Used Laplacian positional encoding to capture global protein structural information.