Abstract: Highlights•Develop a Python-based, open-source toolbox (ACTION) for computer-aided fMRI analysis.•Enable fMRI data augmentation, brain network construction, network feature extraction.•Support deep learning model construction and offer federated learning strategies.•Provide pretrained deep learning foundation models using 3,800+ unlabeled fMRI scans.•Demonstrate ACTION’s effectiveness and user-friendliness based on real fMRI data.
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