Multi-parametric MRI to FMISO PET Synthesis for Hypoxia Prediction in Brain Tumors

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Daniele Perlo, Georgia Kanli, Selma Boudissa, Olivier Keunen

Published: 2024, Last Modified: 03 Mar 2026DGM4MICCAI@MICCAI 2024EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: This research paper presents a novel approach to the prediction of hypoxia in brain tumors, using multi-parametric Magnetic Resonance Imaging (MRI). Hypoxia, a condition characterized by low oxygen levels, is a common feature of malignant brain tumors associated with poor prognosis. Fluoromisonidazole Positron Emission Tomography (FMISO PET) is a well-established method for detecting hypoxia in vivo, but it is expensive and not widely available.